histidine has been researched along with glutamine in 446 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 161 (36.10) | 18.7374 |
1990's | 104 (23.32) | 18.2507 |
2000's | 121 (27.13) | 29.6817 |
2010's | 43 (9.64) | 24.3611 |
2020's | 17 (3.81) | 2.80 |
Authors | Studies |
---|---|
Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
Deleo, AB; Magasanik, B; Streicher, SL | 1 |
Carfi, J; Hoffmann, FM; Kenney, R; Wedler, FC | 1 |
Conti, SF; LaMarre, AG; Straley, SC | 1 |
Bender, RA; Magasanik, B | 1 |
Ruttkay-Nedecký, G; Veselá, V | 1 |
Ames, GF; Esmon, B; Hui, SP; Kustu, SG; McFarland, NC | 1 |
Kustu, SG; McKereghan, K | 1 |
Umbarger, HE | 1 |
Kamoun, P; Parvy, P | 1 |
Overbeek, GP; Twilt, JC; van Duin, J | 1 |
Roberts, J; Rosenfeld, HJ; Schmid, FA | 1 |
Dozy, AM; Kan, YW; Lie-Injo, LE; Lopes, M; Todd, D | 1 |
Cooper, AJ | 1 |
Beuzard, YG; Brizard, CP; Cacheleux, J; Gibaud, A; Godeau, JF; Rosa, J | 1 |
Kehoe, JS | 1 |
Muller, S; Olitzki, AL | 1 |
Chellemi, F | 1 |
Kamely, D; Rudland, P | 1 |
Kim, H; Patel, MS | 1 |
Bochet, P; Curutchet, P; Lambolez, B; Prado de Carvalho, L; Rossier, J; Stinnakre, J | 1 |
Schröder, G; Schröder, J | 1 |
Cantoni, O; Cattabeni, F; Giacomoni, PU; Sestili, P | 1 |
Cohen, GB; Oprian, DD; Robinson, PR | 1 |
Hirst, K; Piper, PW | 1 |
Coussons, PJ; Johnson, CM; Kelly, SM; Price, NC; Sawyer, L; Smith, B | 1 |
Brown, AJ; Cooper, A; Johnson, CM | 1 |
Salloum, RM; Souba, WW; Stevens, BR | 1 |
Chang, SH; Miran, SG; Raushel, FM | 1 |
Carney, JP; Grabowski, DT; Kelley, MR | 1 |
Bauman, MJ; Mawhinney, TD; Peterson, E; Rarey, KE; Raymer, SL; Schweitzer, VG; Woodson, BT | 1 |
Bosron, WF; Edenberg, HJ; Ehrig, T; Hurley, TD | 1 |
Kilberg, MS; Tamarappoo, BK | 1 |
Graham, HC; Littlechild, JA; Watson, HC; Williams, RJ | 1 |
La Mar, GN; Mizukami, H; Yu, LP | 1 |
Kilberg, MS; Mailliard, ME | 1 |
Jigami, Y; Morikawa, M; Muraki, M; Tanaka, H | 1 |
Meritt, J; Nagele, R; Norcross, ED; Stein, TP; Witkowski, TA | 1 |
Robinson, MA | 1 |
Harris, GW; Howlin, B; Moss, DS | 1 |
Ohta, S; Suzuki, T; Takagi, T | 1 |
Kubitschek, HE; Pai, SR | 1 |
Edmundson, AB; Geysen, HM; Mason, TJ; Tribbick, G | 1 |
Gerok, W; Häussinger, D; Meijer, AJ; Sies, H; Soboll, S; Tager, JM | 1 |
Fisher, SE; Karl, PI; Tkaczevski, H | 1 |
Arata, Y; Nishihara, S; Shimizu, A | 1 |
Bycroft, M; Fersht, AR | 1 |
Burley, SK; Petsko, GA | 1 |
Chauvat, F; Labarre, J; Thuriaux, P | 1 |
Braun, PJ; Dennis, S; Hofsteenge, J; Stone, SR | 1 |
Guest, JR; Laue, ED; Miles, JS; Perham, RN; Radford, SE; Texter, FL | 1 |
Gebhardt, R; Kleemann, E | 1 |
Comolli, R; Giordana, B; Leonardi, MG | 1 |
Amuro, N; Paluh, JL; Zalkin, H | 1 |
Christensen, HN; Vadgama, JV | 2 |
Bartnicki, DE; Kerr, EA; Mizukami, H; Yu, NT | 1 |
Carter, P; Fersht, AR; Lowe, DM; Wilkinson, AJ; Winter, G | 1 |
Birken, S; Bourne, PE; Corfield, PW; Low, BW; Rosen, LS; Sato, A | 1 |
Adams, JG; Heller, P; Tausk, K; Winter, WP | 1 |
Mozes, E; Sela, M; Shaltiel, S | 1 |
Brenchley, JE; Magasanik, B; Prival, MJ | 1 |
Deuel, TF; Prusiner, S | 1 |
Brenchley, JE; Magasanik, B | 1 |
Duffus, JH; Finbow, ME; Paterson, LJ; Slaughter, JC | 1 |
Bender, RA; Brenchley, JE; DeLeo, AB; Magasanik, B; Paris, CG; Prival, MJ; Streicher, SL; Tyler, BM | 1 |
Catanzaro, R; Coletti, A; Levi, G; Morisi, G | 1 |
Bundgaard, L; Winther, A | 1 |
Ellis, HK; Watkins, WB | 1 |
Carbonneau, R; Demers, JM | 1 |
Bray, DF; Kapoor, M; Ward, GW | 1 |
Jensen, RA; Kane, JF | 1 |
Gross, TS; Woods, RA | 1 |
Rudland, PS; Seifert, W | 1 |
Albrycht, D; Deuel, TF; Lerner, A | 1 |
Aktin, E; Bergisadi, N; Güven, KC; Koyuncuoglu, H | 1 |
Pogorelova, TN | 1 |
Asafov, GB; Ekisenina, NI; Ivanova, LM; Lumel'skiĭ, VIa; Smagin, VG | 1 |
Crossley, AC; Evans, PD | 1 |
Györy, AZ; Lingard, JM; Young, JA | 1 |
Perutz, MF | 1 |
Doctor, BP; Sodd, MA | 1 |
Halpern, YS | 1 |
Host, WR; Rush, BF; Serlin, O | 1 |
Mitnick, M; Reichlin, S | 1 |
Aksoy, M; Efremov, GD; Erdem, S; Huisman, TH; Müftüoğlu, A; Schroeder, WA; Shelton, JB; Shelton, JR; Ulitin, ON; Wilson, JB | 1 |
Gibson, K; Harris, P | 1 |
Coulson, RA; Herbert, JD | 1 |
Araya, A; Goodman, M; Maita, T; Matsuda, G; Ota, H; Prychodko, W; Watanabe, B | 1 |
Alimov, IIu; Iur'eva, EA; Marchenko, ZM | 1 |
Ionasescu, V; Mueller, S; Stegink, L; Weinstein, M | 1 |
Negishi, K; Sugawara, K | 1 |
Balasubramanian, M; Myers, RF | 1 |
Lingard, J; Rumrich, G; Young, JA | 1 |
Herbert, JD | 2 |
Arcce, CA; Barra, HS; Caputto, R; Rodriguez, JA | 1 |
Pedersen, RA; Spindle, AI | 1 |
Alben, JO; Bare, GH; Brinhall, B; Bromberg, PA; Jones, RT; Padilla, F | 1 |
Kay, LM; Krieger, M; Stroud, RM | 1 |
Bergström, J; Fürst, P; Norée, LO; Vinnars, E | 1 |
Litwin, J | 1 |
Carlisle, CH; Gorinsky, BA; Mazumdar, SK; Palmer, RA; Yeates, DG | 1 |
De Luca, F; Macaione, S; Ruggeri, P; Tucci, G | 1 |
Stadtman, ER; Woolfolk, CA | 1 |
Kingdon, HS; Stadtman, ER | 2 |
Borek, E; Hay, J; Pillinger, DJ | 1 |
Kishida, Y; Sakakibara, S | 1 |
Nishimura, S; Saneyoshi, M | 1 |
Conrad, ME; Polet, H | 1 |
Kinoshita, Y; Nemoto, G; Ujiie, A | 1 |
Kerr, GR | 1 |
Bowers, CY; Chang, JK; Currie, BL; Folkers, K; Schally, AV; Weil, A | 1 |
Deuel, TF; Stadtman, ER | 1 |
Nester, EW; Roth, CW | 1 |
Belly, RT; Claus, GW | 1 |
Gross, W; Ring, K | 1 |
Berlin, RD; Tsan, MF | 1 |
Brignon, G; Dumas, BR; Grosclaude, F; Mercier, JC | 1 |
Chen, R; Doolittle, RF | 1 |
Gibbons, RJ; Loesche, WJ | 1 |
Kotelchuck, D; Scheraga, HA | 1 |
Geisler, C; Höcker, P; Stacher, A; Wiser, M | 1 |
Gerron, GG; Howard, CH; Rudman, D; Vogler, WR | 1 |
Holland, JF; Onuma, T; Waligunda, J | 1 |
Jones, OW; Nirenberg, MW | 1 |
Barois, A; Caldera, R; Escourolle, R; Goulon, M; Grosbuis, S; Nouailhat, F | 1 |
Kapoor, IJ; Tandon, RN | 1 |
Brand, K; Hackenberg, K; Hess, B; Jekat, F; Kofrányi, E | 1 |
Nakamura, T; Okami, Y; Seki, Y | 1 |
McKean, CM; Peterson, NA | 1 |
Golovach, VM; Ratich, IB | 1 |
Delaunay, J; Maleknia, N; Schapira, G | 1 |
Hageman, EC; Larson, BL; Schingoethe, DJ | 1 |
Demeyer, DI; Henderickx, HK | 1 |
Jardetzky, O; Markley, JL; Putter, I | 1 |
Manahan, J; Mandl, I | 1 |
Steenbergen, ST; Weinberg, ED | 1 |
Schneider, G | 1 |
Dietel, K; Schmöger, R | 1 |
Coulson, RA; Hernandez, T | 1 |
Beisel, WR; Dangerfield, HG; Feigin, RD | 1 |
Menden, E; Vangala, RR | 1 |
Gross, E; Van Campen, D | 1 |
Gordon, WG; Greenberg, R; Kalan, EB; Walter, M | 1 |
Kaufman, N; Kinney, TD; Klavins, JV; Kroe, DJ | 1 |
Munier, RL; Sarrazin, G | 1 |
Neumann, PZ; Silverberg, M | 1 |
Andreeva, LA | 1 |
Neumann, PZ; Sass-Kortsak, A | 1 |
Hubbard, JS; Stadtman, ER | 2 |
Kruck, TP; Sarkar, B | 1 |
Lea, PJ; Miflin, BJ; Wallsgrove, RM | 1 |
Hynes, MJ; Polkinghorne, MA | 1 |
Cooper, WN; Farmilo, RK; Fleming, PJ; Hughes, WG; Wyatt, K | 1 |
Hong, J; Hunt, AG | 1 |
Demigné, C; Fafournoux, P; Le Cam, A; Rémésy, C | 1 |
Lapointe, J | 1 |
Wold, F | 1 |
Kilberg, MS | 1 |
Arimasa, N; Harano, K; Harano, T; Mori, H; Shibata, S; Ueda, S | 1 |
Prusiner, SB | 1 |
Braunitzer, G; Liljeqvist, G; Paléus, S | 1 |
Grinde, B; Seglen, PO | 1 |
Christensen, HN; Handlogten, ME; Kilberg, MS | 1 |
McDonald, IK; Thornton, JM | 1 |
Clogston, CL; Fausset, PR; Herman, AC; Lu, HS; Rohde, MF; Sotos, LS; Stoney, KS | 1 |
Häussinger, D; Lang, F; Schreiber, R; Stoll, B | 1 |
Furesz, TC; Moe, AJ; Smith, CH | 1 |
Clement, C; de Hon, FD; Ehlers, M; Herrman, J; Kishimoto, T; Ohsugi, Y; Rose-John, S; Taga, T; ten Boekel, E; Yasukawa, K | 1 |
Aasa, R; Adelroth, P; Brzezinski, P; Gennis, RB; Malmström, BG; Mitchell, DM | 1 |
Boudon, C; Garandeau, P; Lobaccaro, JM; Lumbroso, S; Montoya, P; Romer, TE; Sultan, C; Szarras-Czapnik, M | 1 |
Biron, KK; Chou, S; Erice, A; Hanson, MN; Preheim, LC; Talarico, CL | 1 |
Gasset, M; Gavilanes, JG; Lacadena, J; Mancheño, JM; Martínez del Pozo, A; Martinez-Ruiz, A; Oñaderra, M | 1 |
Cantoni, O; Cattabeni, F; Murray, D; Sestili, P | 1 |
Hilgenfeld, R | 1 |
Kivirikko, KI; Lamberg, A; Pihlajaniemi, T | 1 |
Bocchini, V; Krab, IM; Parmeggiani, A; Scarano, G | 1 |
Offer, G; Sessions, R | 1 |
Carper, DA; Hohman, TC; Old, SE | 1 |
Nath, U; Udgaonkar, JB | 1 |
Baykov, AA; Cooperman, BS; Goldman, A; Lahti, R; Magretova, NN; Velichko, IS; Velichko, IV; Volk, SE | 1 |
Granner, DK; Moller, DE; Printz, RL; Stratton, IM; Vidal-Puig, A | 1 |
Dean, DR; DeRose, VJ; Hoffman, BM; Kim, CH; Newton, WE | 1 |
Rennie, MJ; Tadros, LB; Taylor, PM; Willhoft, NM | 1 |
Gibbs, MR; Leslie, AG; Lewendon, A; Murray, IA; Shaw, WV | 1 |
Ahlman, B; Andersson, K; Hedenborg, L; Leijonmarck, CE; Ljungqvist, O; Wernerman, J | 1 |
Ohta, T; Taguchi, H | 1 |
Higaki, T; Kogo, K; Metzler, CM; Metzler, DE; Mollova, ET; Morino, Y; Scott, RD; Tanase, S | 1 |
Antonio, BJ; Vik, SB | 1 |
Kitamura, K; Shibata, D; Takano, T; Takeda, G; Wang, WH | 1 |
Assmann, G; Chen-Haudenschild, C; Chirazi, A; Funke, H; Köhler, E; Schönfeld, R; Schulte, H; Schwarz, S; Steinmetz, A; von Eckardstein, A | 1 |
Faure, H; Favier, A; Fussellier, M; Guiraud, P; Harraki, B; Richard, MJ; Rochat, MH | 1 |
Fujii, J; Ikeda, Y; Taniguchi, N | 2 |
Accornero, P; Carrera, G; Curti, B; Vanoni, MA | 1 |
deMel, VS; Doscher, MS; Edwards, BF; Glinn, MA; Martin, PD; Ram, ML | 1 |
Ahmed, A; Maxwell, DL; Rennie, MJ; Taylor, PM | 1 |
Assmann, G; Funke, H; Heinrich, J; Köhler, E; Schönfeld, R; Schulte, H; Steinmetz, A; von Eckardstein, A | 1 |
Steyaert, J; Wyns, L | 1 |
Bakker, A; Finkelstein, SD; Sayegh, R; Swalsky, P | 1 |
Davisson, VJ; Klem, TJ | 1 |
Baykov, AA; Cooperman, BS; Dudarenkov, VY; Goldman, A; Husgafvel, S; Hyytiä, T; Käpylä, J; Kasho, VN; Lahti, R; Salminen, T | 1 |
Chapman, SK; Gaume, B; Lederer, F; Manson, FD; Reid, GA; Sharp, RE | 1 |
Rao, VS; Seshadri, K; Vishveshwara, S | 1 |
Braden, BC; Dall'Acqua, W; Fields, BA; Goldbaum, FA; Mariuzza, RA; Poljak, RJ; Schwarz, FP; Ysern, X | 1 |
Ge, SJ; Zhang, LX | 1 |
Boucher, D; Griveau, JF; Grizard, G; Le Lannou, D; Renard, P; Sion, B | 1 |
Brew, K; Grobler, JA; Malinovskii, VA; Tian, J | 1 |
Dementieva, LA; Fedorchuk, VV; Lamzin, VS; Matorin, AD; Mezentzev, AV; Popov, VO; Rojkova, AM; Savitsky, PA; Tishkov, VI | 1 |
Fothergill-Gilmore, LA; Nairn, J; Price, NC; Price, RM | 1 |
Amons, R; Batelaan, D; Bemini, LF; Geenen, A; Giordano, PC; Harteveld, CL; Kok, PJ | 1 |
Giraldo, J; Gordon-Beresford, RM; Van Belle, D; Wodak, SJ | 1 |
Batelaan, DN; Bernini, LF; Brand, A; Giordano, PC; Harteveld, CL; Kluin-Nelemans, HC; Plug, RJ; Willems, LN | 1 |
Cody, LB; Sly, WS; Tamai, S; Waheed, A | 1 |
Petersen, BO; Shuman, S | 1 |
Ishimori, K; Kitagawa, T; Morishima, I; Mukai, M; Tanaka, M | 1 |
Guth, HJ; Kraatz, G; Rose, HJ; Wiersbitzky, M; Ziesche, M | 1 |
Crews, BC; Gierse, JK; Hauser, SD; Landino, LM; Marnett, LJ | 1 |
Bernard, A; Demuyter, P; Erbs, P; Jund, R | 1 |
He, MM; Kaback, HR | 1 |
Baykov, AA; Cooperman, BS; Dudarenkov, VY; Goldman, A; Hyytiä, T; Kasho, VN; Lahti, R; Mikalahti, K; Velichko, IS | 1 |
De Vos, S; Doumen, J; Langhorst, U; Steyaert, J | 1 |
Fowkes, RL; Keep, RF; Xiang, J | 1 |
Cook, JD; Fairbanks, VF; Hoyer, JD; Kechteiger, KS; Thibodeau, SN; Wick, MJ | 1 |
Earhart, CA; Matsumura, M; Mitchell, DT; Murray, DL; Ohlendorf, DH; Pinheiro, DM; Schlievert, PM | 1 |
Beck, M; Sakmar, TP; Siebert, F | 1 |
Fillingame, RH; Valiyaveetil, FI | 1 |
Holden, HM; Howard, AJ; Miran, SG; Phillips, JC; Raushel, FM; Thoden, JB | 1 |
Nakae, T; Ono, T; Yoneyama, H; Yoshihara, E | 1 |
Drysdale, GR; Hsu, F; Kurz, LC; Nakra, T; Plungkhen, W; Riley, M; Stein, R | 1 |
Bocian, DF; Brudvig, GW; Chisholm, DA; Cua, A; Diner, BA; Stewart, DH | 1 |
Loke, P; Sim, TS | 1 |
Afink, GB; Hamel, BC; Hol, FA; Joosten, PH; Mariman, EC; Peters, H; van Beersum, SE; van Zoelen, EJ | 1 |
Abdelkarim, GE; Ennis, SR; Kawai, N; Keep, RF; Ren, XD | 1 |
Christendat, D; Saridakis, VC; Turnbull, JL | 1 |
Dilworth, MJ; Fisher, K; Kim, CH; Newton, WE | 1 |
Gehring, MR; Holman, CM; Kan, CC; Van Wart, HE | 1 |
Kass, IJ; Sampson, NS | 1 |
Barry, PH; Jacques, P; Moorhouse, AJ; Schofield, PR | 1 |
Suzuki, K; Tanaka, T; Yamada, T | 1 |
Alberts, IL; Nadassy, K; Wodak, SJ | 1 |
Kass, IJ; Sampson, NS; Vrielink, A; Yue, QK | 1 |
Arninkhof, MJ; Kersten, MA; Op den Camp, HJ; van der Drift, C; Van Griensven, LJ | 1 |
LeBrun, LA; Plapp, BV | 1 |
Drohat, AC; Ferguson, E; Jagadeesh, J; Stivers, JT | 1 |
Drohat, AC; Gilliland, GL; Jagadeesh, J; Pankiewicz, KW; Stivers, JT; Tordova, M; Watanabe, KA; Xiao, G | 1 |
Aubry, M; Becchi, M; Couprie, N; Dementhon, L; Francina, A; Lacan, P; Souillet, G | 1 |
Buchanan, GR; Fairbanks, VF; Farah, RA; Hoyer, JD; Phillips, L; Snow, K; Timmons, CF | 1 |
Holden, HM; Huang, X; Raushel, FM; Thoden, JB | 1 |
Ibarra-Molero, B; Loladze, VV; Makhatadze, GI; Sanchez-Ruiz, JM | 1 |
Das, TK; Ferguson-Miller, S; Gennis, RB; Lee, HM; Mills, D; Rousseau, DL | 1 |
Esposito, L; Mazzarella, L; Sica, F; Sorrentino, G; Vitagliano, L; Zagari, A | 1 |
Magistrini, M; Palmer, E; Trimeche, A; Vidament, M; Yvon, JM | 1 |
Dove, JE; Klinman, JP; Schwartz, B; Williams, NK | 1 |
Granadino, B; Ortega, A; Penalva, LO; Ruiz, MF; Sánchez, L; Segarra, C; Valcárcel, J; Vicente, L | 1 |
Mandal, D; Rao, R; Woolf, TB | 1 |
Eswar, N; Ramakrishnan, C | 1 |
Aguiar, J | 1 |
Koo, LS; Li, H; Ortiz de Montellano, PR; Poulos, TL; Schuller, DJ; Yano, JK | 1 |
Miernyk, JA; Randall, DD; Thelen, JJ | 1 |
Atwood, CS; Bush, AI; Huang, X; Khatri, A; Kim, YS; Moir, RD; Roher, AE; Scarpa, RC; Tanzi, RE | 1 |
Evans, PR; Leadlay, PF; Thomä, NH | 1 |
Ferry, JG; Tripp, BC | 1 |
Canters, GW; Dennison, C; Diederix, RE | 1 |
Jez, JM; Noel, JP | 1 |
Brudvig, GW; Diner, BA; Nixon, PJ; Stewart, DH | 1 |
Antonio, L; Burchell, B; Fournel-Gigleux, S; Magdalou, J; Netter, P; Ouzzine, M | 1 |
Arndt, R; Dorn, S; Frers, CR; Kochhan, L; Schmidt, W; Simon-Schultz, J | 1 |
Hitomi, K; Ishikawa, T; Iwai, S; Kim, ST; Mizukoshi, T; Nakamura, H; Todo, T | 1 |
Baker, EN; Edwards, RA; Jameson, GB; Whittaker, JW; Whittaker, MM | 1 |
Popov, KM; Tuganova, A; Yoder, MD | 1 |
Camacho, P; Gu, S; Jiang, JX; Roderick, HL | 1 |
Christiansen, J; Dean, DR; Hales, BJ; Lemon, BJ; Peters, JW; Sørlie, M | 1 |
Christensen, T; DiTusa, CA; Fierke, CA; Mahapatro, M; McCall, KA; Toone, EJ | 1 |
Baticci, F; Biasi, S; Bozzetti, F; Cozzaglio, L; Facchetti, G | 1 |
Glavas, S; Tanner, ME | 1 |
Batra, R; Khayat, R; Lagacé, L; Massariol, MJ; Tong, L | 1 |
Furey, W; Guo, F; Hübner, G; Jordan, F; Liu, M; Sergienko, EA; Tittmann, K; Wang, J | 1 |
Banaszak, LJ; Barycki, JJ; O'Brien, LK; Strauss, AW | 1 |
Iwata, Y; Kasuya, A; Miyamoto, S | 1 |
Bangera, MG; McGuire, KA; Olsen, JG; Siggaard-Andersen, M; von Wettstein-Knowles, P | 1 |
Hong, M; Yao, XL | 1 |
Benning, MM; Dunaway-Mariano, D; Holden, HM; Luo, L; Taylor, KL; Wei, Y; Yang, G; Zhang, W | 1 |
Benton, PM; Dean, DR; Hoffman, BM; Mayer, SM; Seefeldt, LC; Shao, J | 1 |
Boukhvalova, M; Hirschman, A; Stewart, RC; VanBruggen, R; Wolfe, AJ | 1 |
Ajayi, WU; Chaudhuri, M; Hill, GC | 1 |
Hickman, HD; Hildebrand, WH; McIlhaney, MM; Schenk, EL; Solheim, JC; Turnquist, HR | 1 |
Brieba, LG; Padilla, R; Sousa, R | 1 |
Colman, RF; Huang, YC | 1 |
Chang, CK; Ho, C; Simplaceanu, V | 1 |
Abramczyk, BA; Gursky, SK; Postel, EH; Xu, Y | 1 |
Palecz, B | 1 |
Boffi, A; Draghi, F; Miele, AE; Vallone, B | 1 |
Chiou, SH; Huang, KF; Ko, TP; Wang, AH; Yuann, JM | 1 |
Legler, PM; Massiah, MA; Mildvan, AS | 1 |
Leland, PA; Raines, RT; Sevcik, J; Urbanikova, L | 1 |
Barry, BA; Pujols-Ayala, I | 1 |
Allen, JP; Kálmán, L; LoBrutto, R; Narváez, AJ; Williams, JC | 1 |
Baker, SF; Edwards, SH; Thompson, D; Wilton, DC; Wood, SP | 1 |
Howell, EE; Saxton, AM; Smiley, RD; Stinnett, LG | 1 |
Dang, BN; Fitch, CA; García-Moreno E, B; Schwehm, JM; Stites, WE | 1 |
Chopra, P; Drlica, K; Koul, A; Ramachandran, S; Singh, A; Singh, Y; Tyagi, AK | 1 |
Daubner, SC; Ellis, HR; Fitzpatrick, PF; Ralph, EC; Willmon, OJ | 1 |
D'Orso, I; De Gaudenzi, JG; Frasch, AC | 1 |
Balcar, VJ; Bröer, A; Bröer, S; Bubb, WA; Conigrave, AD; Hare, N; McEwan, SR; McQuillan, JA; Rae, C | 1 |
Blaskó, B; Fésüs, L; Mádi, A | 1 |
Behnken, LJ; Francina, A; Galactéros, F; Préhu, C; Promé, D; Wajcman, H | 1 |
Brooks, WS; Fisher, C; Fonte, J; Ghika, J; Gnjec, A; Martins, RN; Masters, CL; McLean, CA; Mehta, PD; Miklossy, J; Suard, F; Suva, D; Taddei, K; Verdile, G | 1 |
Bao, Y; Curthoys, NP; Hamm, B; Kenny, J; Taylor, L; Toth, A; Wagers, B | 1 |
FRIEDMAN, ME; ROESSLER, WG | 1 |
AGNIHOTRI, VP | 1 |
O'BARR, TP | 1 |
NOZAKI, Y; TANFORD, C | 1 |
AKIYA, S; NAKAI, T; TSUJIGADO, N | 1 |
FRIBERG, UA; GLIMCHER, MJ; MECHANIC, GL; TRAVIS, DF | 1 |
ZYGMUNT, WA | 1 |
GERIFFIN, G; KESNER, L; MUNTWYLER, E | 1 |
FELIX, WR; KOPIN, IJ; LABROSSE, EH; WESTLAKE, RJ | 1 |
GAEVSKAYA, MS; GERSHTEIN, LM; NOSOVA, EA; PORTUGALOV, VV | 1 |
Makarov, AA; Mitkevich, VA; Newsom, S; Pace, CN; Shaw, KL; Trevino, S; Yakovlev, GI | 1 |
Casali, M; Roberts, MF; Zambonelli, C | 1 |
Jahng, WJ; Rando, RR; Xue, L | 1 |
Bruix, M; García-Mayoral, MF; Gavilanes, JG; Ibarra-Molero, B; Lacadena, J; Martínez del Pozo, A; Pérez-Cañadillas, JM; Rico, M; Sanchez-Ruiz, JM; Santoro, J | 1 |
Cao, C; Huang, ZX; Wang, YF; Wang, YH; Wang, ZQ; Wu, H; Zhang, Q | 1 |
Birgander, PL; Kasrayan, A; Sjöberg, BM | 1 |
Berst, KB; Höög, JO; Plapp, BV; Strömberg, P; Svensson, S | 1 |
Adinolfi, BS; Cacciamani, T; De Vendittis, E; Gogliettino, MA; Sciré, A; Tanfani, F; Ursby, T | 1 |
LeBrun, LA; Park, DH; Plapp, BV; Ramaswamy, S | 1 |
Harrison, DH; Marks, GT; Susler, M | 1 |
Chan, AY; Ma, ES; Wong, WS; Yip, SF | 1 |
Aktories, K; Lang, S; Orth, JH | 1 |
Church, FC; Fortenberry, YM; Gentry, HR; Leung, LL; Myles, T; Whinna, HC | 1 |
Klingen, AR; Ullmann, GM | 1 |
Ginalski, K; Zemojtel, T | 1 |
Chou, KC; Du, QS; Guo, H; Sirois, S; Wang, SQ; Wei, DQ; Zhu, Y | 1 |
Buckingham, RH; Champ, S; Heurgué-Hamard, V; Kisselev, LL; Merkoulova-Rainon, T; Merkulova-Rainon, T; Mora, L | 1 |
Abonyi, M; Folhoffer, A; Lakatos, PL | 1 |
Drazen, JM; Glimcher, LH; Hwang, ES; Lake, SL; Peng, SL; Raby, BA; Richter, BG; Silverman, ES; Tantisira, KG; Weiss, ST | 1 |
Antonyuk, S; Barrett, ML; Eady, RR; Ellis, MJ; Harris, RL; Hasnain, SS; Hough, MA; Sawers, G | 1 |
Albrecht, J; Hertz, L; Hilgier, W; Schousboe, A; Sonnewald, U; Waagepetersen, HS; Ziemińska, E | 1 |
Cendoroglo, MS; Cupples, LA; Lahoz, C; Lamon-Fava, S; Martinez, TL; Ordovas, JM; Schaefer, EJ; Wilson, PW | 1 |
Grewer, C; Tao, Z | 1 |
Dalal, S; Starcevic, D; Sweasy, J | 1 |
Relyea, HA; Rimkus, S; van der Donk, WA; Wheatley, JL; Woodyer, R | 1 |
Boswell, EL; Pletnev, V; Scaccia, LA; Thomas, JL; Umland, TC | 1 |
Brenna, JT; Sacks, GL | 1 |
Holland, IB; Jenewein, S; Jumpertz, T; Schmitt, L; Zaitseva, J | 1 |
Albert, ED; McNicholas, A; Sala, M; Volgger, A; Witter, K; Zahn, R | 1 |
Mulkidjanian, AY | 1 |
Camilli, A; Tamayo, R; Tischler, AD | 1 |
Berg-Andersson, UA; Cohen, AS; Kristiansson, MH; Lindh, CH | 1 |
Haska, CL; Hou, Z; Matherly, LH; Stapels, SE | 1 |
Albrecht, J; Aschner, M; Mutkus, L; Sidoryk, M; Wu, Q; Zielińska, M | 1 |
Huang, Y; Lau, SK; Tsoi, HW; Woo, PC; Yuen, KY | 1 |
Choi, SJ; Firatli, E; Hart, PS; Hart, TC; Ozdemir, D; Ozdemir-Karatas, M; Piesco, N; Ryu, OH | 1 |
Butow, RA; Giannattasio, S; Liu, Z; Thornton, J | 1 |
Brijs, K; Campenhout, S; Courtin, CM; De Ranter, CJ; Declerck, PJ; Delcour, JA; Fierens, K; Gebruers, K; Gils, A; Rabijns, A; Robben, J; Sansen, S; Volckaert, G | 1 |
Brownie, ER; Fraser, ME; Hayakawa, K; Hume, MS; Ryan, DG | 1 |
Andersen, PM; Collinge, J; Fisher, EM; Hardiman, O; Highley, R; Ince, PG; Morrison, KE; Pall, HS; Parkinson, N; Shaw, PJ; Skibinski, G; Smith, MO | 1 |
Ernst, R; Horn, C; Koch, J; Schmitt, L; Tampé, R | 1 |
Fernández, M; Zúñiga, M | 1 |
Lapinski, PE; Perria, CL; Raghavan, M; Rajamanickam, V | 1 |
Böcker, U; Haas, SL; Ruether, A; Schreiber, S; Singer, MV | 1 |
Jayakumar, AR; Norenberg, MD; Pichili, VB; Rao, KV | 1 |
Antonozzi, I; Carducci, C; Criscuolo, C; De Michele, G; De Rosa, A; Filla, A; Giovanniello, T; Menchise, V; Striano, S; Xhoxhi, E | 1 |
Bendall, DS; Hirst, J; Howe, CJ; Luisi, BF; Marcaida, MJ; Moorlen, RJ; Reda, T; Schlarb-Ridley, BG; Wastl, J; Worrall, JA | 1 |
Borgstahl, GE; Bronshteyn, Y; Brunold, TC; Grove, LE; Miller, AF; Porta, J; Vahedi-Faridi, A; Yikilmaz, E | 1 |
Cherninkova, S; Jelev, H; Kremensky, I; Mihaylova, V; Raycheva, M; Savov, A; Todorov, T; Tournev, I | 1 |
Buchenau, B; Kahnt, J; Krüger, M; Mahlert, F; Shima, S; Thauer, RK | 1 |
Benson, DR; Cowley, AB; Wang, L | 1 |
Ilkovski, B; Koy, A; Laing, N; Mayatepek, E; Neuen-Jacob, E; North, K; Voit, T; Weis, J | 1 |
Li, H; Sun, H; Zeng, YB; Zhang, DM | 1 |
Alarcón, VB; Marikawa, Y; Tamashiro, DA | 1 |
Rodriguez-Granillo, A; Sedlak, E; Wittung-Stafshede, P | 1 |
Seah, SY; Wang, W | 1 |
Abiko, F; Fujita, Y; In, Y; Ishida, T; Kitamura, K; Miyagawa, H; Mizuno, A; Tomoo, K | 1 |
Inoue, N; Kasahara, M; Miyaishi, A; Osawa, K; Osawa, Y; Shimada, E; Tabuchi, Y; Takahashi, J; Tanaka, K; Tsutou, A; Yamamoto, M; Yoshida, K | 1 |
Betz, NA; Engel, L; Godat, B; Johnson, TM | 1 |
Borchelt, DR; Cao, X; Carroll, MC; Culotta, VC; Hart, PJ; Holloway, SP; Proescher, JB; Schuermann, JP; Winkler, DD | 1 |
Bertolacini, CD; Ribeiro-Bicudo, LA; Richieri-Costa, A | 1 |
Donglan, S; Na, W; Rongmiao, Z; Yan, L; Yanan, D; Zhifeng, C | 1 |
Fausto, R; Reva, I; Rozenberg, M; Shoham, G | 1 |
Diebold, AR; Egger, S; Nidetzky, B; Solomon, EI; Straganz, GD | 1 |
Norenberg, MD; Rama Rao, KV; Reddy, PV; Tong, X | 1 |
Babu, GN; Bala, L; Kalita, J; Khetrapal, CL; Kumar, A; Misra, UK; Singh, RL | 1 |
Barbiroli, A; Bernini, F; Bonomi, F; Calabresi, L; Favari, E; Franceschini, G; Gomaraschi, M; Iametti, S; Pozzi, S; Putt, WE; Talmud, PJ | 1 |
Gouvea, IE; James, MN; Juliano, L; Juliano, MA; Kondo, MY; Oda, K; Okamoto, DN; Pillai, B; Santos, JA | 1 |
Bishop, GM; Campbell, MS; Ralph, DM; Robinson, SR | 1 |
Behera, RK; Goyal, S; Mazumdar, S | 1 |
Dobritzsch, D; Lindqvist, Y; Lohkamp, B; Voevodskaya, N | 1 |
Ablett, GR; Luk-Labey, SY; Peter Pauls, K; Poysa, VW; Rajcan, I; Reinprecht, Y; Yu, K | 1 |
Anttila, S; Huuhka, M; Illi, A; Kampman, O; Lehtimäki, T; Leinonen, E; Mononen, N; Setälä-Soikkeli, E; Viikki, M | 1 |
Sun, H; Yang, N; Zeng, YB | 1 |
Bettati, S; Bosisio, C; Campanini, B; Chirico, G; Collini, M; D'Alfonso, L; Quercioli, V; Raboni, S | 1 |
Acosta, O; Alvarez, V; Avello, R; Bacon, JA; Cornejo-Olivas, M; Cosentino, C; Díaz-Grez, F; Dieguez, E; Farrer, MJ; Layson, L; Marca, V; Mata, IF; Mazzetti, P; Medina, AC; Micheli, F; Miranda, M; Ortega, O; Perandones, C; Perez-Pastene, C; Raggio, V; Ross, OA; Segura-Aguilar, J; Torres, L; Trujillo-Godoy, O; Venegas, P; Vilariño-Güell, C; Wilhoite, GJ; Yearout, D; Zabetian, CP | 1 |
Elliott, JL; Luther, C; Puttaparthi, K; Son, M; Srikanth, U | 1 |
Kaila, VR; Sharma, V; Wikström, M | 1 |
Balaram, P; Banerjee, M; Ramakrishnan, C; Vasudev, PG | 1 |
Breman, C; Delanghe, J; Gahutu, JB; Masaisa, F; Mukiibi, J; Philippé, J | 1 |
Di Nardo, G; Gilardi, G; Goyal, A; Sideri, A; Tsotsou, GE | 1 |
Ashida, H; Gohda, J; Inoue, J; Kim, M; Kobayashi, T; Koyama, T; Mimuro, H; Mizushima, T; Nagai, S; Ogawa, M; Oyama, A; Sanada, T; Sasakawa, C; Shibata, Y; Suzuki, M | 1 |
Busse, E; Deeg, N; Halimeh, S; Kappert, G; Sandrock, K; Sauer, K; Wiegering, V; Zieger, B | 1 |
Aasly, JO; Appel-Cresswell, S; Encarnacion, M; Farrer, MJ; Jon Stoessl, A; Rajput, A; Rajput, AH; Shah, B; Sherman, H; Szu-Tu, C; Thompson, C; Trinh, J; Vilarino-Guell, C; Weir, D; Yu, I | 1 |
Chenvidhya, D; Fujii, T; Honjo, S; Jedpiyawongse, A; Matharit, M; Miwa, M; Ohshima, K; Ohta, E; Sripa, B; Srivatanakul, P; Tanaka, H; Tanaka, M; Viwatthanasittiphong, C; You, G; Zeng, L | 1 |
Alnajjar, KS; Hosler, J; Prochaska, L | 1 |
CHANARIN, I; ROTHMAN, D; WATSON-WILLIAMS, EJ | 1 |
Bahl, M; Barnes, T; Bell, K; Califaretti, N; Campbell, C; DiSebastiano, KM; Dubin, JA; Hanning, R; Mourtzakis, M; Russell, C; Vance, V | 1 |
Almkvist, I; Bagchi, S; Fredriksson, R; Hägglund, MGA; Hellsten, SV; Karlsson, E; Löfqvist, E; Nilsson, VCO; Philippot, G; Sreedharan, S; Tafreshiha, A | 1 |
Hong, M; Schmidt-Rohr, K; Wang, T; Williams, JK | 1 |
Giblin, D; Gross, ML; Niu, B; Rempel, DL; Zhang, H | 1 |
Joshi, D; Korgaonkar, S; Shanmukhaiah, C; Vundinti, BR | 1 |
Braas, D; Christofk, HR; Graeber, TG; Krall, AS; Xu, S | 1 |
Buschiazzo, A; Drusin, SI; Larrieux, N; Lisa, MN; Morán-Barrio, J; Moreno, DM; Viale, AM; Vila, AJ | 1 |
Avrova, SV; Borovikov, YS; Borys, D; Chernev, AA; Karpicheva, OE; Moraczewska, J; Rysev, NA; Śliwińska, M | 1 |
Ghosh, B; Goyal, VD | 1 |
Hayashi, F; Kigawa, T; Konagaya, Y; Matsugami, A; Miyakawa, R; Nishimura, C; Sato, M; Watanabe, S | 1 |
Asano, Y; Kameya, M | 1 |
Ahn, J; Bang, YJ; Choi, SH; Ha, NC; Jo, I; Kim, D | 1 |
Bonetta, R; Borowski, T; Fadia, HBR; Garcia-Fandiño, R; Hunter, GJ; Hunter, T; Sacco, A; Stockner, T; Sultana, PM; Trinh, CH; Vella, M | 1 |
Born, DA; Drennan, CL; Ju, KS; Peck, SC; Ulrich, EC; van der Donk, WA | 1 |
Chatterji, T; Gupta, M; Nagesh Babu, G; Paliwal, VK; Roy, R; Singh, S | 1 |
Gang, K; He, J; Liu, X; Lu, H; Luo, L; Tang, X; Yang, Q; Zou, Q | 1 |
Garza-Lopez, E; Hagen, J; Lee, A; Lopez, JA; Meiner, V; Sheffer, R | 1 |
Batskinis, MA; Hamodrakas, SJ; Iconomidou, VA; Litou, ZI; Nastou, KC | 1 |
Fest, J; Goeman, JJ; Haller, T; Hveem, K; Ikram, A; Joensuu, A; Männistö, S; Metspalu, A; Mikkel, K; Ness-Jensen, E; Perola, M; Ruiter, R; Stricker, BH; Tonisson, N; van Duijn, CM; van Eijck, CHJ; van Ommen, GB; Veth, O; Vijfhuizen, LS; ʼt Hoen, PAC | 1 |
Badaoui, M; Ballandras-Colas, A; Berta, D; Cherepanov, P; Cook, NJ; Engelman, AN; Kotecha, A; Li, W; Nans, A; Rosta, E | 1 |
Holeček, M | 2 |
Aghababaie, AS; Arya, VB; Buchanan, CR; Colclough, K; Ford-Adams, M; Kapoor, RR | 1 |
Deng, L; Zhou, ZH | 1 |
Abdel-Hamid, MS; Al-Maraghi, A; Al-Owain, M; Alhashem, AM; Alkuraya, FS; Alsaif, HS; Beetz, C; Breilyn, MS; Coban Akdemir, Z; Danish, E; Du, H; Duberstein, S; El-Anany, E; Elsea, SH; Fakhro, KA; Fatih, JM; Ferla, MP; Gaba, C; Gibbs, RA; Gijavanekar, C; Gleeson, JG; Guliyeva, S; Guliyeva, U; Haseeb, A; Houlden, H; Hunter, JV; Jhangiani, SN; Kaiyrzhanov, R; Karageorgou, V; Liu, N; Lupski, JR; Marafi, D; Maroofian, R; Mitani, T; Mullegama, SV; Pehlivan, D; Posey, JE; Rosenfeld, JA; Sebastin, M; Sites, E; Subhi, AA; Sutton, VR; Taylor, JC; Torti, E; Zaki, MS; Zakkariah, M | 1 |
Braczkowski, M; Rowińska-Żyrek, M; Szebesczyk, A; Wątły, J; Witkowska, D | 1 |
Amadieu, C; Bindels, LB; Cani, PD; Cnop, M; Cserjesi, R; Delzenne, NM; Demeure, R; Hanhineva, K; Kärkkäinen, O; Klein, O; Leyrolle, Q; Luminet, O; Neyrinck, AM; Paquot, N; Rodriguez, J; Thissen, JP | 1 |
Anjum Zia, M; Jahan, N; Kiran, S; Mujtaba, N; Naqvi, SAR; Sultana, B | 1 |
Fan, W; McDougal, MB; Schoggins, JW | 1 |
Bröer, S; Das, A; Gauthier-Coles, G; Rae, CD | 1 |
Hu, D; Hu, L; Jiao, D; Li, G; Li, X; Li, Z; Liu, S; Qi, L; Wu, H; Zhao, C | 1 |
Bai, Y; Chen, Y; Cheng, B; Liu, Y; Xu, S; Yang, X | 1 |
Adamski, J; Ardanaz, E; Barranco, MR; Bonet, C; Breeur, M; Bueno-de-Mesquita, B; Chirlaque, MD; Dossus, L; Eichelmann, F; Ferrari, P; Grioni, S; Gunter, MJ; Heath, AK; His, M; Jenab, M; Johansson, M; Kaaks, R; Katzke, V; Keski-Rahkonen, P; Keun, H; Key, TJ; Kyrø, C; Laouali, N; Manjer, J; Muller, D; Nøst, TH; Olsen, KS; Overvad, K; Palli, D; Panico, S; Quirós, JR; Rentoft, M; Rinaldi, S; Rothwell, JA; Sacerdote, C; Sandanger, TM; Sandsveden, M; Scalbert, A; Schmidt, JA; Schulze, MB; Severi, G; Tjønneland, A; Travis, RC; Tsilidis, K; Tumino, R; Viallon, V; Vidman, L | 1 |
Achaintre, D; Adamski, J; Amiano, P; Ardanaz, E; Bešević, J; Boutron-Ruault, MC; Breeur, M; Bueno-de-Mesquita, B; Chadeau-Hyam, M; Colorado-Yohar, S; Cross, AJ; Dahm, CC; Derksen, JWG; Dimou, N; Eichelmann, F; Eriksen, AK; Ferrari, P; Gicquiau, A; Gunter, MJ; Huybrechts, I; Jenab, M; Kaaks, R; Katzke, V; Keun, H; Murphy, N; Nøst, TH; Overvad, K; Palli, D; Pasanisi, F; Prehn, C; Rinaldi, S; Rothwell, JA; Sánchez, MJ; Sandanger, TM; Scalbert, A; Schulze, MB; Severi, G; Skeie, G; Smith-Byrne, K; Tjønneland, A; Travis, R; Tsilidis, KK; Tumino, R; van Guelpen, B; Viallon, V; Vidman, L; Vineis, P; Wedekind, R; Zamora-Ros, R | 1 |
Brown, K; Huff-Lonergan, EJ; Johnson, LG; Lonergan, SM; N Nair, M; Prenni, JE; Zhai, C | 1 |
Duan, Y; Lai, J; Li, L; Shao, L; Wang, J; Wang, Y; Xing, X; Yang, Z | 1 |
12 review(s) available for histidine and glutamine
Article | Year |
---|---|
Amino acid biosynthesis and its regulation.
Topics: Amino Acids; Arginine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Histidine; Phenylalanine; Pyruvates; Serine; Tyrosine | 1978 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
[Synthesis of peptides by solid phase method. 1].
Topics: Arginine; Asparagine; Cysteine; Esters; Glutamine; Histidine; Lysine; Methionine; Methods; Peptides; Polystyrenes; Serine; Threonine | 1971 |
Glutamine metabolism in higher plants.
Topics: Ammonia; Anthranilate Synthase; Aspartate-Ammonia Ligase; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Chloroplasts; Glucosamine; Glutamate Synthase; Glutamate-Ammonia Ligase; Glutamine; Histidine; Isoenzymes; Nitrogen; Plants; Purines; Transaminases; Tryptophan | 1981 |
[Regulation of transcription by elements of the translation system in Escherichia coli].
Topics: Bacillus subtilis; Escherichia coli; Glutamate-tRNA Ligase; Glutamates; Glutamine; Histidine; Lac Operon; Operon; Phenylalanine; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Transcription, Genetic; Tryptophan | 1980 |
In vivo chemical modification of proteins (post-translational modification).
Topics: Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Glutamates; Glutamine; Histidine; Hydroxylysine; Lysine; Phenylalanine; Proline; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Serine; Threonine; Tryptophan; Tyrosine | 1981 |
Amino acid transport in isolated rat hepatocytes.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Catecholamines; Cell Membrane; Cells, Cultured; Cysteine; Glucagon; Glucocorticoids; Glutamine; Glycine; Histidine; In Vitro Techniques; Insulin; Kinetics; Liver; Lysine; Rats | 1982 |
Disorders of glutamate metabolism and neurological dysfunction.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glutathione; Histidine; Humans; Ketoglutaric Acids; Nervous System Diseases; Proline; Pyrrolidonecarboxylic Acid | 1981 |
[Wilson disease].
Topics: Adenosine Triphosphatases; Cation Transport Proteins; Copper; Copper-Transporting ATPases; Glutamine; Hepatolenticular Degeneration; Histidine; Humans; Mutation | 2004 |
Ubiquinol oxidation in the cytochrome bc1 complex: reaction mechanism and prevention of short-circuiting.
Topics: Catalytic Domain; Electron Transport; Electron Transport Complex III; Glutamine; Histidine; Models, Biological; Oxidation-Reduction; Ubiquinone | 2005 |
Amino acid catabolic pathways of lactic acid bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Aromatic; Amino Acids, Branched-Chain; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Biodegradation, Environmental; Fermentation; Food Microbiology; Glutamate Decarboxylase; Glutamic Acid; Glutamine; Histidine; Lactic Acid; Lactobacillus; Proline | 2006 |
Histidine in Health and Disease: Metabolism, Physiological Importance, and Use as a Supplement.
Topics: Amino Acids, Branched-Chain; Ammonia; Chelating Agents; Contraindications; Dermatitis, Atopic; Dietary Supplements; Filaggrin Proteins; Free Radical Scavengers; Glutamine; Histamine; Histidine; Humans; Hypertrophy; Liver; Liver Diseases; Metabolic Syndrome; Nervous System Diseases; Organ Preservation Solutions | 2020 |
3 trial(s) available for histidine and glutamine
Article | Year |
---|---|
Analysis of the hexokinase II gene in subjects with insulin resistance and NIDDM and detection of a Gln142-->His substitution.
Topics: Adult; Amino Acid Sequence; Base Sequence; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; DNA Primers; Exons; Female; Genetic Variation; Glutamine; Glycated Hemoglobin; Hexokinase; Histidine; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Isoenzymes; Male; Molecular Sequence Data; Obesity; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prospective Studies | 1995 |
Metabolic effects of intraportal nutrition in humans.
Topics: Amino Acids; Blood Urea Nitrogen; Female; Glutamine; Histidine; Humans; Male; Middle Aged; Muscle, Skeletal; Parenteral Nutrition; Portal Vein; Postoperative Care; Prealbumin; Proteins; Rectal Neoplasms; Rectum; Serum Albumin | 2001 |
TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Alleles; Asthma; Child; Child, Preschool; Clinical Trials as Topic; Cytokines; Dexamethasone; DNA, Complementary; Female; Genetic Variation; Genotype; Glutamine; Histidine; Humans; Male; Mutagenesis, Site-Directed; Phenotype; T-Box Domain Proteins; Th1 Cells; Th2 Cells; Time Factors | 2004 |
431 other study(ies) available for histidine and glutamine
Article | Year |
---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Regulation of enzyme formation in Klebsiella aerogenes by episomal glutamine synthetase of Escherichia coli.
Topics: Ammonia-Lyases; Ammonium Sulfate; Cell-Free System; Enterobacter; Enterobacteriaceae; Escherichia coli; Extrachromosomal Inheritance; Genes; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamine; Histidine; Histidine Ammonia-Lyase; Mutation; Plasmids | 1976 |
Maintainance of specificity, information, and thermostability in thermophilic Bacillus sp. glutamine synthetase.
Topics: Adenine Nucleotides; Amino Acids; Bacillus; Bacillus subtilis; Cations, Divalent; Geobacillus stearothermophilus; Glutamate-Ammonia Ligase; Glutamine; Glycine; Histidine; Hot Temperature; Kinetics; Ligands; Magnesium; Manganese; Molecular Weight; Protein Conformation | 1976 |
Chemotaxis toward amino acids by Bdellovibrio bacteriovorus.
Topics: Amino Acids; Asparagine; Bdellovibrio; Chemotaxis; Cysteine; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Lysine; Temperature; Threonine | 1977 |
Regulatory mutations in the Klebsiella aerogenes structural gene for glutamine synthetase.
Topics: Ammonia; Enzyme Repression; Genes; Glutamate-Ammonia Ligase; Glutamine; Histidine; Klebsiella pneumoniae; Mutation | 1977 |
Effect of amino acid replacement on the stability of the tobacco mosaic virus protein structure.
Topics: Glutamine; Histidine; Mutation; Peptides; Polarography; Protein Conformation; Protein Denaturation; Sodium Hydroxide; Tobacco Mosaic Virus; Viral Proteins | 1977 |
Nitrogen control of Salmonella typhimurium: co-regulation of synthesis of glutamine synthetase and amino acid transport systems.
Topics: Amino Acids; Bacterial Proteins; Biological Transport, Active; Carrier Proteins; Genes, Regulator; Glutamate-Ammonia Ligase; Glutamine; Histidine; Mutation; Salmonella typhimurium | 1979 |
Mutations affecting glutamine synthetase activity in Salmonella typhimurium.
Topics: Cell-Free System; Chromosome Mapping; Conjugation, Genetic; Genes; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamine; Histidine; Hot Temperature; Mutation; Recombination, Genetic; Salmonella typhimurium; Stereoisomerism; Transduction, Genetic | 1975 |
[Effect of n-dipropyl-acetate on the elimination of urinary amino acids].
Topics: Alanine; Amino Acids; Child; Glutamates; Glutamine; Glycine; Histidine; Humans; Male; Ornithine; Serine; Valproic Acid | 1978 |
Translational fidelity and specificity of ribosomes cleaved by cloacin DF13.
Topics: Bacteriocins; Escherichia coli; Glutamine; Histidine; Kinetics; Magnesium; Protein Biosynthesis; Ribosomes | 1979 |
Biologic and antineoplastic effects of enzyme-mediated in vivo depletion of L-glutamine, L-tryptophan, and L-histidine.
Topics: Animals; Asparaginase; Enzymes; Female; Glutaminase; Glutamine; Histidine; Histidine Ammonia-Lyase; Indoles; Mice; Mice, Inbred Strains; Mixed Function Oxygenases; Neoplasms, Experimental; Tryptophan | 1979 |
The alpha-globin gene adjacent to the gene for HbQ-alpha 74 Asp replaced by His is deleted, but not that adjacent to the gene for HbG-alpha 30 Glu replaced by Gln; three-fourths of the alpha-globin genes are deleted in HbQ-alpha-thalassemia.
Topics: Aspartic Acid; Chemical Phenomena; Chemistry; Chromosome Deletion; DNA; Genetic Carrier Screening; Globins; Glutamates; Glutamine; Hemoglobin H; Hemoglobins, Abnormal; Histidine; Humans; Hybridization, Genetic; Peptides; Thalassemia | 1979 |
Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between L-phenylalanine and alpha-keto-gamma-methiolbutyrate.
Topics: Animals; Cytosol; Female; Glutamine; Histidine; Kidney; Male; Methionine; Mitochondria; Molecular Weight; Phenylalanine; Pyruvates; Rats; Transaminases | 1978 |
Association of hemoglobin Saint Etienne (alpha2beta295F8 His replaced by G1n) with hemoglobins A and F. Synthesis and subunit exchange in vitro.
Topics: Adult; Amino Acids; Blood Group Antigens; Child; Erythrocytes; Female; Fetal Hemoglobin; France; Glutamine; Hemoglobins; Hemoglobins, Abnormal; Histidine; Humans; Kinetics; Macromolecular Substances; Male; Pedigree; Peptide Fragments; Protein Binding; Trypsin | 1976 |
Electrogenic effects of neutral amino acids on neurons of Aplysia californica.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cyanides; Dinitrophenols; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ganglia; Glutamates; Glutamine; Histidine; Kinetics; Leucine; Membrane Potentials; Mollusca; Neural Conduction; Ouabain; Potassium; Sodium; Stereoisomerism; Temperature | 1976 |
Further investigations on M. leprae. Growth promotion and inhibition by organic substances and observations on antagonistic and syntergistic effects.
Topics: Cysteine; Deferoxamine; Dimethyl Sulfoxide; Drug Antagonism; Drug Synergism; Glutamates; Glutamine; Histidine; Mycobacterium leprae; Purines; Pyrimidines; Tryptophan | 1975 |
Synthesis by conventional methods of human growth hormone peptide fragments. I.
Topics: Alanine; Asparagine; Aspartic Acid; Glutamine; Growth Hormone; Histidine; Humans; Leucine; Lysine; Optical Rotation; Peptides; Phenylalanine; Serine; Threonine; Tyrosine | 1975 |
Nutrient-dependent arrest of fibroblast growth is partially reversed by insulin but not fibroblast growth factor.
Topics: Biological Transport; Cell Division; Cell Line; DNA; Fibroblasts; Glutamine; Growth Substances; Histidine; Insulin; Leucine; Methionine; Phosphates | 1976 |
Characterization of two site-specifically mutated human dihydrolipoamide dehydrogenases (His-452----Gln and Glu-457----Gln).
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; Dihydrolipoamide Dehydrogenase; Escherichia coli; Flavin-Adenine Dinucleotide; Genetic Vectors; Glutamates; Glutamic Acid; Glutamine; Histidine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oligodeoxyribonucleotides; Protein Conformation; Recombinant Proteins | 1992 |
In the GluR1 glutamate receptor subunit a glutamine to histidine point mutation suppresses inward rectification but not calcium permeability.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Barium; Base Sequence; Calcium; Calcium Channels; Cloning, Molecular; Evoked Potentials; Glutamates; Glutamine; Histidine; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oocytes; Plasmids; Quinoxalines; Receptors, Glutamate; Receptors, Neurotransmitter; Transcription, Genetic; Xenopus laevis | 1992 |
A single change of histidine to glutamine alters the substrate preference of a stilbene synthase.
Topics: Acyltransferases; Amino Acid Sequence; Binding Sites; Glutamine; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Plants; Plasmids; Sequence Homology, Amino Acid; Substrate Specificity | 1992 |
L-glutamine prevents the L-histidine-mediated enhancement of hydrogen peroxide-induced cytotoxicity.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cytotoxins; DNA Damage; DNA, Single-Stranded; Drug Interactions; Glutamine; Histidine; Hydrogen Peroxide | 1992 |
Mechanism of activation and inactivation of opsin: role of Glu113 and Lys296.
Topics: Animals; Cattle; Cell Line; Darkness; Glutamine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Histidine; Hydrogen-Ion Concentration; Lysine; Mutagenesis; Retinaldehyde; Rhodopsin; Rod Opsins; Transducin | 1992 |
Starvation for His-tRNAHis in yeast causes translational arrest without a high level of misincorporation of glutamine at histidine codons.
Topics: Codon; Glutamine; Histidine; Histidine-tRNA Ligase; Mutation; Phosphoglycerate Kinase; Polyribosomes; Protein Biosynthesis; RNA, Transfer, Amino Acyl; RNA, Transfer, His; Saccharomyces cerevisiae; Temperature | 1992 |
Selective modification by transglutaminase of a glutamine side chain in the hinge region of the histidine-388----glutamine mutant of yeast phosphoglycerate kinase.
Topics: Amino Acid Sequence; Catalysis; Chromatography, High Pressure Liquid; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Glutamine; Histidine; Molecular Sequence Data; Mutation; Peptide Mapping; Phosphoglycerate Kinase; Putrescine; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Transglutaminases; Trypsin | 1991 |
A comparison of the reactivity and stability of wild type and His388----Gln mutant phosphoglycerate kinase from yeast.
Topics: Amino Acid Sequence; Ammonium Sulfate; Calorimetry; Circular Dichroism; Glutamine; Histidine; Kinetics; Mutagenesis, Site-Directed; Phosphoglycerate Kinase; Protein Conformation; Protein Denaturation; Saccharomyces cerevisiae; Sulfhydryl Compounds; Thermodynamics | 1991 |
Adaptive regulation of brush-border amino acid transport in a chronic excluded jejunal limb.
Topics: Alanine; Anastomosis, Roux-en-Y; Asparagine; Biological Transport, Active; Glucose; Glutaminase; Glutamine; Histidine; Jejunum; Kinetics; Microvilli; Sodium | 1991 |
Role of the four conserved histidine residues in the amidotransferase domain of carbamoyl phosphate synthetase.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Escherichia coli; Glutaminase; Glutamine; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Plasmids; Sequence Homology, Nucleic Acid | 1991 |
An adult male specific gene in Drosophila containing the repetitive element opa.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cloning, Molecular; Drosophila; Glutamine; Histidine; Male; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid | 1991 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
General base catalysis in a glutamine for histidine mutant at position 51 of human liver alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Binding, Competitive; Catalysis; Decanoic Acids; Ethanol; Glutamine; Histidine; Humans; Isoenzymes; Kinetics; Liver; Mutagenesis; NAD; Trifluoroethanol | 1991 |
Functional reconstitution of the hepatic system N amino acid transport activity.
Topics: Animals; Asparagine; Biological Transport, Active; Cell Membrane; Detergents; Glutamine; Histidine; Kinetics; Liposomes; Liver; Membrane Proteins; Polyethylene Glycols; Proteolipids; Rats; Substrate Specificity | 1991 |
A proton-NMR study of a site-directed mutation (His388----Glu) in the interdomain region of yeast phosphoglycerate kinase. Implications for domain movement.
Topics: Glutamine; Glyceric Acids; Histidine; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Phosphoglycerate Kinase; Protein Conformation; Saccharomyces cerevisiae | 1991 |
Rearrangement of the distal pocket accompanying E7 His----Gln substitution in elephant carbonmonoxy- and oxymyoglobin: 1H NMR identification of a new aromatic residue in the heme pocket.
Topics: Animals; Binding Sites; Elephants; Glutamine; Heme; Histidine; Kinetics; Magnetic Resonance Spectroscopy; Myoglobin; Phenylalanine; Protein Conformation; Structure-Activity Relationship | 1990 |
Sodium-dependent neutral amino acid transport by human liver plasma membrane vesicles.
Topics: Adult; Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Cell Membrane; Cysteine; Glutamine; Histidine; Humans; Kinetics; Liver; Sodium | 1990 |
A structural requirement in the subsite F of lysozyme. The role of arginine 115 in human lysozyme revealed by site-directed mutagenesis.
Topics: Arginine; Binding Sites; Catalysis; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Glutamine; Histidine; Humans; Hydrogen Bonding; Kinetics; Lysine; Muramidase; Mutation | 1989 |
Glutamine and smooth muscle morphology of the gut in rats on total parenteral nutrition.
Topics: Animals; Glutamine; Histidine; In Vitro Techniques; Intestinal Mucosa; Intestines; Male; Methylhistidines; Muscle, Smooth; Parenteral Nutrition, Total; Rats; Rats, Inbred Strains | 1989 |
Allelic sequence variations in the hypervariable region of a T-cell receptor beta chain: correlation with restriction fragment length polymorphism in human families and populations.
Topics: Alleles; Amino Acid Sequence; Base Sequence; Blotting, Southern; Cloning, Molecular; Genes; Genetic Variation; Genetics, Population; Glutamine; Histidine; Humans; Macromolecular Substances; Molecular Sequence Data; Oligonucleotide Probes; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Receptors, Antigen, T-Cell | 1989 |
Segmented anisotropic refinement of bovine ribonuclease A by the application of the rigid-body TLS model.
Topics: Animals; Arginine; Asparagine; Aspartic Acid; Cattle; Chemical Phenomena; Chemistry, Physical; Glutamates; Glutamine; Histidine; Mathematics; Models, Molecular; Phenylalanine; Ribonuclease, Pancreatic; Sulfates; Tyrosine; X-Ray Diffraction | 1989 |
Amino acid sequence of the dimeric hemoglobin (Hb I) from the deep-sea cold-seep clam Calyptogena soyoae and the phylogenetic relationship with other molluscan globins.
Topics: Amino Acid Sequence; Animals; Bivalvia; Glutamine; Hemoglobins; Histidine; Molecular Sequence Data; Mollusca; Peptide Hydrolases; Phylogeny | 1989 |
Activation of amino acid transport during steady-state growth of Escherichia coli.
Topics: Amino Acids; Biological Transport, Active; Escherichia coli; Glutamine; Glycine; Histidine; In Vitro Techniques | 1989 |
Similar binding properties of peptide ligands for a human immunoglobulin and its light chain dimer.
Topics: Bence Jones Protein; Chemical Phenomena; Chemistry, Physical; Dinitrobenzenes; Endorphins; Enkephalins; Glutamine; Histidine; Humans; Immunoglobulin G; Ligands; Myeloma Proteins; Peptides | 1989 |
Role of plasma membrane transport in hepatic glutamine metabolism.
Topics: Amino Acids; Animals; Biological Transport, Active; Cell Membrane; Cytosol; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutamine; Histidine; In Vitro Techniques; Liver; Male; Mitochondria, Liver; Rats; Rats, Inbred Strains; Sodium | 1985 |
Characteristics of histidine uptake by human placental microvillous membrane vesicles.
Topics: Aminoisobutyric Acids; Anions; Biological Transport, Active; Cations; Cysteine; Ethylmaleimide; Female; Gluconates; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Microvilli; Osmolar Concentration; Phenylalanine; Placenta; Pregnancy; Sodium; Temperature | 1989 |
Mn2+-probe ESR method for the analyses of the dissociation of charged residues on the surface of immunoglobulins.
Topics: Asparagine; Binding Sites, Antibody; Crystallography; Electron Spin Resonance Spectroscopy; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Immunoglobulin A; Immunoglobulin Fab Fragments; Immunoglobulin Fc Fragments; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Manganese; Myeloma Proteins | 1986 |
Assignment of histidine resonances in the 1H NMR (500 MHz) spectrum of subtilisin BPN' using site-directed mutagenesis.
Topics: Bacillus; Cloning, Molecular; Glutamine; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mutation; Subtilisins | 1988 |
Amino-aromatic interactions in proteins.
Topics: Arginine; Asparagine; Crystallography; Glutamine; Histidine; Lysine; Proteins | 1986 |
Genetic analysis of amino acid transport in the facultatively heterotrophic cyanobacterium Synechocystis sp. strain 6803.
Topics: Amino Acids; Arginine; Biological Transport, Active; Cyanobacteria; Glutamine; Histidine; Leucine; Lysine; Membrane Transport Proteins; Mutation | 1987 |
Use of site-directed mutagenesis to investigate the basis for the specificity of hirudin.
Topics: Amino Acid Sequence; Animals; Escherichia coli; Glutamine; Hirudins; Histidine; Kinetics; Lysine; Molecular Sequence Data; Mutation; Recombinant Proteins; Thrombin | 1988 |
Site-directed mutagenesis and 1H NMR spectroscopy of an interdomain segment in the pyruvate dehydrogenase multienzyme complex of Escherichia coli.
Topics: Amino Acid Sequence; Base Sequence; Chromosome Deletion; Escherichia coli; Genes; Genes, Bacterial; Glutamine; Histidine; Hydrogen; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Weight; Mutation; Pyruvate Dehydrogenase Complex | 1988 |
Hormonal regulation of amino acid transport system N in primary cultures of rat hepatocytes.
Topics: Amino Acids; Animals; Biological Transport; Cells, Cultured; Dexamethasone; Glucagon; Glutamine; Histidine; Insulin; Kinetics; Liver; Male; Rats; Rats, Inbred Strains | 1987 |
Histidine transport in plasma membrane vesicles from rat liver.
Topics: Alanine; Animals; Biological Transport; Cell Membrane; Glutamine; Histidine; Kinetics; Liver; Male; Membrane Potentials; Potassium; Rats; Rats, Inbred Strains; Sodium; Thiocyanates | 1988 |
Replacement by site-directed mutagenesis indicates a role for histidine 170 in the glutamine amide transfer function of anthranilate synthase.
Topics: Anthranilate Synthase; Escherichia coli; Genes; Genes, Bacterial; Genotype; Glutaminase; Glutamine; Histidine; Kinetics; Mutation; Oligodeoxyribonucleotides; Plasmids; Serratia marcescens | 1985 |
Discrimination of Na+-independent transport systems L, T, and asc in erythrocytes. Na+ independence of the latter a consequence of cell maturation?
Topics: Amino Acids; Biological Transport, Active; Erythrocyte Aging; Erythrocytes; Ethylmaleimide; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Leucine; Sodium; Threonine; Tryptophan; Tyrosine | 1985 |
Resonance Raman studies of CO and O2 binding to elephant myoglobin (distal His(E7)----Gln).
Topics: Animals; Carbon Monoxide; Elephants; Glutamine; Histidine; Myoglobin; Oxygen; Spectrum Analysis, Raman; Whales | 1985 |
Probing histidine-substrate interactions in tyrosyl-tRNA synthetase using asparagine and glutamine replacements.
Topics: Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Asparagine; Binding Sites; Genes; Geobacillus stearothermophilus; Glutamine; Histidine; Kinetics; Models, Molecular; Mutation; Protein Binding; Protein Conformation; Tyrosine-tRNA Ligase | 1985 |
Erabutoxin b. Initial protein refinement and sequence analysis at 0.140-nm resolution.
Topics: Amino Acid Sequence; Disulfides; Elapid Venoms; Erabutoxins; Glutamine; Histidine; Models, Molecular; Protein Conformation; Proteins; X-Ray Diffraction | 1985 |
Hemoglobin Rush (beta 101 (g3) glutamine): a new unstable hemoglobin causing mild hemolytic anemia.
Topics: Adult; Amino Acids; Anemia, Hemolytic; Arginine; Autoanalysis; Blood Protein Electrophoresis; Chicago; Densitometry; Female; Glutamates; Glutamine; Hemoglobins, Abnormal; Histidine; Hot Temperature; Humans; Oxygen; Pedigree; Peptides; Protein Denaturation; Staining and Labeling; Trypsin | 1974 |
The genetic control of the immune response to different antigenic determinants within the synthetic polypeptide poly(His, Glu)-polyPro-polyLys.
Topics: Animals; Antibody Formation; Cross Reactions; Crosses, Genetic; Epitopes; Erythrocytes; Freund's Adjuvant; Genes; Glutamine; Hemagglutination Tests; Histidine; Histocompatibility Testing; Immune Sera; Immunization; Immunogenetics; Lymphocytes; Lysine; Mice; Mice, Inbred A; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Molecular Weight; Peptides; Proline; Sheep; Spleen | 1974 |
Regulation of the synthesis of enzymes responsible for glutamate formation in Klebsiella aerogenes.
Topics: Amino Acid Oxidoreductases; Ammonia; Bacteriophages; Diazooxonorleucine; Enterobacter; Enzyme Repression; Galactosidases; Genotype; Glucose; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Histidine; Histidine Ammonia-Lyase; Ketoglutaric Acids; Mutation; Phenotype; Species Specificity; Transaminases | 1973 |
Regulation of glutamine synthetase from Bacillus subtilis by divalent cations, feedback inhibitors, and L-glutamine.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Ammonia; Bacillus subtilis; Feedback; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Glycine; Histidine; Kinetics; Magnesium; Manganese; Tryptophan | 1974 |
Mutants of Klebsiella aerogenes lacking glutamate dehydrogenase.
Topics: Alkanesulfonates; Ammonia; Cell-Free System; Citrate (si)-Synthase; Citrates; Culture Media; Genes; Glucose; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Histidine; Klebsiella; Mutagens; Mutation; Transaminases; Transduction, Genetic | 1974 |
Glutamine amido transferase in yeast: changes in activity during the cell cycle.
Topics: Adenosine Monophosphate; Cell Division; Enzyme Induction; Glutamate-Ammonia Ligase; Glutamine; Histidine; Magnesium; Manganese; Saccharomyces; Time Factors; Transferases; Tryptophan | 1974 |
Glutamine synthetase as a regulator of enzyme synthesis.
Topics: Ammonia; Chromosome Mapping; Enzyme Activation; Enzyme Repression; Galactosidases; Genes; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Histidine; Histidine Ammonia-Lyase; Klebsiella; Membrane Transport Proteins; Mutation; Tryptophan | 1974 |
Free amino acids in fish brain: normal levels and changes upon exposure to high ammonia concentrations in vivo, and upon incubation of brain slices.
Topics: Amino Acids; Ammonia; Animals; Brain; Brain Chemistry; Fishes; Glucose; Glutamates; Glutamine; Histidine; In Vitro Techniques; Kidney; Liver; Rats; Time Factors | 1974 |
Argininosuccinic aciduria in hereditary hair diseases.
Topics: Adolescent; Adult; Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Chromatography, Paper; Cystinuria; Female; Glutamates; Glutamine; Glycine; Hair; Histidine; Humans; Infant; Lysine; Male; Middle Aged; Serine; Skin Diseases; Threonine; Tyrosine; Valine | 1968 |
The designation of the major guinea-pig neural lobe protein as a neurophysin.
Topics: Animals; Antigens; Biological Assay; Cross Reactions; Cysteine; Cystine; Electrophoresis, Polyacrylamide Gel; Glutamine; Glycine; Guinea Pigs; Histidine; Immunodiffusion; Isoleucine; Lysine; Male; Methionine; Molecular Weight; Neurophysins; Pituitary Gland, Posterior; Sulfur Radioisotopes; Tyrosine | 1973 |
[Hepatic steatosis and cholesterolemia in the domestic duckling in the course of protein malnutrition on a rice diet].
Topics: Animals; Arginine; Deficiency Diseases; Fatty Liver; Glutamine; Glycine; Growth; Histidine; Hypercholesterolemia; Isoleucine; Leucine; Lysine; Methionine; Oryza; Phenylalanine; Poultry Diseases; Protein Deficiency; Threonine; Tryptophan; Valine | 1965 |
Glutamine synthetase of Neurospora crassa. Inactivation by urea and protection by some substrates and allosteric effectors.
Topics: Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Glutamates; Glutamine; Glycine; Histidine; Ligases; Magnesium; Molecular Weight; NAD; Neurospora; ortho-Aminobenzoates; Sulfhydryl Compounds; Urea | 1969 |
Metabolic interlock. The influence of histidine on tryptophan biosynthesis in Bacillus subtilis.
Topics: Bacillus subtilis; Binding Sites; Culture Media; Depression, Chemical; Enzyme Activation; Enzyme Repression; Feedback; Glutamine; Histidine; Kinetics; Ligases; Models, Biological; Models, Chemical; Mutation; ortho-Aminobenzoates; Pentosephosphates; Phosphoric Acids; Phosphotransferases; Species Specificity; Stimulation, Chemical; Transferases; Tryptophan | 1970 |
Identification of mutants defective in the first and second steps of de novo purine synthesis in Saccharomyces cerevisiae.
Topics: Adenosine Triphosphate; Amino Sugars; Animals; Chickens; Colorimetry; Culture Media; Diphosphates; Enzyme Repression; Genetics, Microbial; Glutamine; Glycine; Histidine; Inosine Nucleotides; Ligases; Liver; Mutation; Pentosephosphates; Pentosyltransferases; Purines; Ribose; Saccharomyces; Saccharomyces cerevisiae; Transferases | 1971 |
Cyclic nucleotides and growth control in cultured mouse cells: correlation of changes in intracellular 3':5' cGMP concentration with a specific phase of the cell cycle.
Topics: Animals; Blood; Cell Division; Cell Line; Cells, Cultured; Culture Media; Cyclic AMP; Cyclic GMP; DNA; Fibroblasts; Glutamine; Histidine; Kinetics; Leucine; Methionine; Mice; Phosphates; Thymidine; Tritium | 1974 |
Regulatory properties of rat liver glutamine synthetase.
Topics: Animals; Citrates; Electrophoresis, Polyacrylamide Gel; Glutamate-Ammonia Ligase; Glutamine; Histidine; Ketoglutaric Acids; Liver; Magnesium; Manganese; Rats; Sodium Dodecyl Sulfate; Urea | 1972 |
Lipolytic and hypoglycemic compounds obtained from cystoseira barbata J. Ag.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Blood Glucose; Chromatography, Gel; Chromatography, Paper; Eukaryota; Glutamine; Histidine; Leucine; Lipid Metabolism; Lysine; Methionine; Peptide Fragments; Rabbits; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
[Amino acid composition of proteins of the placenta and the fetal membranes in abortion].
Topics: Abortion, Spontaneous; Asparagine; Cystine; Extraembryonic Membranes; Female; Glutamine; Histidine; Humans; Lysine; Placenta; Pregnancy; Proteins; Valine | 1974 |
[Amino acid levels in the blood serum of patients with chronic colitis].
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea | 1974 |
Free amino acids in the haemocytes and plasma of the larva of Calliphora vicina.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Blood Cells; Blood Coagulation; Diptera; Glutamates; Glutamine; Glycine; Hemolymph; Histidine; Isoleucine; Larva; Leucine; Lysine; Methionine; Phenylalanine; Plasma; Proline; Serine; Taurine; Threonine; Tyrosine; Valine | 1974 |
Proceedings: Proximal tubular inhomogeneity for neutral amino acids in the rat kidney.
Topics: Absorption; Amino Acids; Animals; Cyclopentanes; Glutamine; Histidine; Kidney Tubules, Proximal; Leucine; Perfusion; Rats | 1974 |
Stereochemical interpretation of high oxygen affinity of haemoglobin Little Rock ( 2 2 143His leads to Gln).
Topics: Diphosphoglyceric Acids; Glutamine; Hemoglobins, Abnormal; Histidine; Humans; Models, Structural; Oxygen; Oxyhemoglobins; Protein Conformation | 1973 |
Nucleotide sequences of transfer ribonucleic acids.
Topics: Alanine; Arginine; Aspartic Acid; Base Sequence; Biological Evolution; Escherichia coli; Evaluation Studies as Topic; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Serine; Species Specificity; Tryptophan; Tyrosine; Valine | 1974 |
Hyperalimentation in cirrhotic patients.
Topics: Acid-Base Equilibrium; Acidosis; Alanine Transaminase; Alkaline Phosphatase; Amino Acids; Ammonia; Arginine; Carbon Dioxide; Caseins; Catheterization; Cysteine; Diet Therapy; Fibrin; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Liver Cirrhosis; Lysine; Methionine; Parenteral Nutrition; Phenylalanine; Potassium; Sodium; Threonine; Tryptophan | 1972 |
Enzymatic synthesis of thyrotropin releasing hormone (TRH) by hypothalamic "TRH synthetase".
Topics: Adenosine Triphosphate; Amides; Animals; Autoradiography; Carbon Isotopes; Chlorides; Chromatography, Thin Layer; Electrophoresis; Glutamates; Glutamine; Histidine; Hypothalamus; In Vitro Techniques; Iodoacetates; Male; Mercury; Proline; Puromycin; Rats; Ribonucleases; Swine; Thyrotropin-Releasing Hormone | 1972 |
Hemoglobin Istanbul: substitution of glutamine for histidine in a proximal histidine (F8(92) ).
Topics: Adult; Amino Acid Sequence; Amino Acids; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Electrophoresis, Starch Gel; Glutamine; Hemoglobinopathies; Hemoglobins, Abnormal; Histidine; Hot Temperature; Humans; Hydrogen-Ion Concentration; Male; Molecular Weight; Mutation; Peptides; Splenectomy; Tryptophan | 1972 |
Aminoacyl-transfer-ribonucleic acid synthetases in myocardial tissue.
Topics: Amino Acyl-tRNA Synthetases; Animals; Glutamine; Histidine; Humans; Myocardium; Rabbits; Rats; RNA, Transfer; Tyrosine | 1972 |
Amino acid metabolism in chameleon liver.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Citrulline; Female; Glutamates; Glutamine; Glycine; Histidine; Keto Acids; Liver; Lizards; Lysine; Male; Methionine; Ornithine; Phenylalanine; Pyruvates; Serine; Threonine; Tryptophan | 1972 |
Amino acid compositions of all the tryptic peptides from the and polypeptide chains of adult hemoglobin of the slow loris (Nycticebus coucang). Biochemical studies on hemoglobins and myoglobins. X.
Topics: Alanine; Amino Acids; Animals; Arginine; Chromatography; Chromatography, Paper; Glutamine; Hemoglobins; Histidine; Isoleucine; Leucine; Lysine; Methionine; Myoglobin; Peptides; Phenylalanine; Primates; Serine; Threonine; Trypsin; Tyrosine; Valine | 1972 |
[Amino acid metabolism pathology in the convulsive syndrome in young children].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Child, Preschool; Cystine; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Male; Methionine; Proline; Seizures; Serine; Tryptophan; Tyrosine; Valine | 1972 |
Amino acid abnormality in Sjögren-Larsson syndrome.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Dental Enamel Hypoplasia; Epilepsy; Ethylamines; Glutamine; Glycine; Histidine; Humans; Ichthyosis; Intellectual Disability; Isoleucine; Leucine; Lysine; Male; Muscle Spasticity; Retinal Degeneration; Serine; Syndrome; Valine | 1973 |
Effects of some amino acids on the horizontal cell membrane potential in the isolated carp retina.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cyprinidae; Dark Adaptation; Glutamates; Glutamine; Glycine; Histidine; In Vitro Techniques; Leucine; Membrane Potentials; Photic Stimulation; Retina | 1973 |
Nutrient media for plant parasitic nematodes. V. Amino acid nutrition of Aphelenchoides rutgersi.
Topics: Alanine; Amino Acids; Aminobutyrates; Culture Media; Cysteine; Cystine; Glutamine; Histidine; Isoleucine; Leucine; Methionine; Mitosporic Fungi; Nematoda; Phenylalanine; Reproduction; Tyrosine | 1973 |
Reabsorption of L-glutamine and L-histidine from various regions of the rat proximal convolution studied by stationary microperfusion: evidence that the proximal convolution is not homogeneous.
Topics: Animals; Biological Transport, Active; Carbon Isotopes; Fanconi Syndrome; Glutamine; Histidine; Kidney Glomerulus; Kidney Tubules; Kidney Tubules, Proximal; Male; Methods; Perfusion; Rats; Time Factors | 1973 |
Amino acid metabolism in chameleon tissues.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brain; Citrulline; Glutamates; Glutamine; Glycine; Histidine; Ketoglutaric Acids; Kidney; Liver; Lysine; Muscles; Myocardium; Ornithine; Oxaloacetates; Proline; Pyruvates; Reptiles; Serine; Tryptophan | 1973 |
Uncorporation of phenylalanine as a single unit into rat brain protein: reciprocal inhibition by phenylalanine and tyrosine of their respective incorporations.
Topics: Adenosine Triphosphate; Aging; Animals; Asparagine; Brain; Carbon Radioisotopes; Glutamates; Glutamine; Histidine; In Vitro Techniques; Kidney; Kinetics; Liver; Magnesium; Methionine; Nerve Tissue Proteins; Phenylalanine; Potassium; Rats; Thyroid Gland; Tritium; Tryptophan; Tyrosine | 1973 |
Hatching, attachment, and outgrowth of mouse blastocysts in vitro: fixed nitrogen requirements.
Topics: Amino Acids, Essential; Animals; Blastocyst; Chorionic Gonadotropin; Collagen; Culture Media; Cystine; Female; Glutamine; Gonadotropins, Equine; Histidine; Immune Sera; In Vitro Techniques; Methionine; Mice; Nitrogen; Ovulation; Threonine; Tryptophan; Tyrosine; Valine | 1973 |
Hemoglobin Little Rock (beta143 (H21) His leads to Gln). Effects of an amino acid substitution at the 2,3-diphosphoglycerate binding site.
Topics: Amino Acid Sequence; Amino Acids; Arkansas; Binding Sites; Chlorides; Chromatography, Ion Exchange; Diphosphoglyceric Acids; Electrophoresis, Disc; Glutamine; Hemoglobins, Abnormal; Histidine; Humans; Kinetics; Mathematics; Models, Chemical; Oxygen; Peptide Fragments; Phosphates; Protein Binding; Spectrophotometry; Trypsin | 1974 |
Structure and specific binding of trypsin: comparison of inhibited derivatives and a model for substrate binding.
Topics: Amidines; Animals; Arginine; Aspartic Acid; Cattle; Glutamine; Histidine; Isoflurophate; Lysine; Models, Structural; Protein Binding; Protein Conformation; Trypsin; Trypsin Inhibitors; X-Ray Diffraction | 1974 |
Intracellular free amino acid concentration in human muscle tissue.
Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine | 1974 |
Growth of human diploid fibroblasts in media with different amino acid composition.
Topics: Amino Acids; Cell Adhesion; Cell Division; Culture Media; Cystine; Fibroblasts; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lung; Methionine; Phenylalanine; Pyruvates; Stimulation, Chemical; Threonine; Tyrosine; Valine | 1974 |
The structure of ribonuclease at 2-5 Angström resolution.
Topics: Amino Acid Sequence; Chloromercuribenzoates; Glutamine; Histidine; Lactones; Lysine; Models, Structural; Platinum; Protein Conformation; Ribonucleases; Water; X-Ray Diffraction | 1974 |
Free amino acids in developing rat retina.
Topics: Aging; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Chromatography, Ion Exchange; Glutamates; Glutamine; Glycine; Histidine; Methionine; Ornithine; Proline; Rats; Retina; Taurine; Time Factors; Tyrosine | 1974 |
Regulation of glutamine synthetase. 3. Cumulative feedback inhibition of glutamine synthetase from Escherichia coli.
Topics: Adenine Nucleotides; Alanine; Carbamates; Cytosine Nucleotides; Escherichia coli; Feedback; Glucosamine; Glutamine; Glycine; Histidine; Kinetics; Ligases; Magnesium; Manganese; Phosphates; Tryptophan | 1967 |
Regulation of glutamine synthetase. X. Effect of growth conditions on the susceptibility of Escherichia coli glutamine synthetase to feedback inhibition.
Topics: Adenine Nucleotides; Alanine; Ammonium Chloride; Calcium; Cobalt; Culture Media; Cytosine Nucleotides; Escherichia coli; Feedback; Glucose; Glutamates; Glutamine; Glycerol; Glycine; Histidine; Leucine; Ligases; Magnesium; Manganese; Nitrites; Oxygen; Tryptophan | 1967 |
Two E. coli glutamine synthetases with different sensitivities to feedback effectors.
Topics: Adenine Nucleotides; Ammonium Chloride; Culture Media; Cytosine Nucleotides; Escherichia coli; Feedback; Glutamine; Glycine; Histidine; Ligases; Tryptophan | 1967 |
Effect of hypermethylation on the functional properties of transfer ribonucleic acid.
Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Cysteine; Escherichia coli; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Methylation; RNA, Bacterial; RNA, Transfer | 1969 |
Selective inactivation of amino acid acceptor and ribosome-binding activities of Escherichia coli tRNA by modification with cyanogen bromide.
Topics: Acylation; Amino Acyl-tRNA Synthetases; Arginine; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Cyanogen Bromide; Escherichia coli; Glutamates; Glutamine; Glycine; Guanine Nucleotides; Histidine; Isoleucine; Kinetics; Lysine; Methylamines; Nucleic Acid Conformation; Phenylalanine; Polynucleotides; Ribosomes; RNA, Transfer; Structure-Activity Relationship; Thiouracil; Tyrosine; Uracil Nucleotides; Uridine; Valine | 1971 |
Malaria: extracellular amino acid requirements for in vitro growth of erythrocytic forms of Plasmodium knowlesi.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Culture Techniques; Cystine; DNA; Erythrocytes; Glutamine; Haplorhini; Histidine; Isoleucine; Lysine; Methionine; Orotic Acid; Plasmodium; Tyrosine | 1968 |
"Dysgonic" strains of mycobacterium tuberculosis on Ogawa's egg medium isolated as pathogens from patients suffering from lung tuberculosis. II. Growth-inhibitory effects of D-asparagine, D-aspartic acid, Dl-serine, or L-serine against "dysgonic".
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Culture Media; Depression, Chemical; Glutamine; Histidine; Humans; Leucine; Mycobacterium tuberculosis; Proline; Serine; Tuberculosis, Pulmonary; Valine | 1967 |
The free amino acids of serum during development of Macaca mulatta. II. During pregnancy and fetal life.
Topics: Amino Acids; Animals; Arginine; Embryonic and Fetal Development; Female; Glutamine; Haplorhini; Histidine; Lysine; Methionine; Pregnancy; Pregnancy, Animal; Taurine; Umbilical Cord | 1968 |
Synthesis and relationship of L-glutaminyl-L-histidyl-L-prolinamide to the thyrotropin releasing hormone.
Topics: Amides; Animals; Biological Assay; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Glutamine; Histidine; Hypothalamus; Iodine; Iodine Isotopes; Methods; Mice; Neurosecretion; Peptides; Proline; Thyroid Gland; Thyrotropin-Releasing Hormone | 1970 |
Some kinetic properties of Bacillus subtilis glutamine synthetase.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Alanine; Ammonia; Bacillus subtilis; Cytosine Nucleotides; Drug Synergism; Enzyme Activation; Escherichia coli; Feedback; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Iron; Kinetics; Ligases; Magnesium; Manganese; Temperature; Tryptophan | 1970 |
Co-ordinate control of tryptophan, histidine and tyrosine enzyme synthesis in Bacillus subtilis.
Topics: Amino Acids; Bacillus subtilis; Chromosome Mapping; Cyclohexanes; Genes; Genetic Code; Genetics, Microbial; Glutamine; Histidine; Ligases; Mutation; Oxidoreductases; Pyruvates; Shikimic Acid; Transaminases; Tryptophan; Tyrosine | 1971 |
Effect of amino acids on the growth of Acetobacter suboxydans.
Topics: Acetobacter; Amino Acids; Culture Media; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Ketoglutaric Acids; Proline; Stimulation, Chemical; Time Factors | 1972 |
Active transport of glutamate in Streptomyces hydrogenans. I. Studies on uptake and pool size, and their interrelationship.
Topics: Aminoisobutyric Acids; Arginine; Asparagine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Cold Temperature; Culture Media; Dinitrophenols; Glutamate Dehydrogenase; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Mathematics; Methionine; Osmosis; Phenylalanine; Protein Biosynthesis; Stereoisomerism; Streptomyces; Temperature; Tyrosine | 1971 |
Membrane transport in the rabbit alveolar macrophage. The specificity and characteristics of amino acid transport systems.
Topics: Amino Acids; Aminocaproates; Animals; Arginine; Biological Transport; Calcium; Carbon Isotopes; Chlorides; Choline; Chromatography, Paper; Extracellular Space; Female; Glutamine; Histidine; Inulin; Kinetics; Lanthanum; Leucine; Lysine; Macrophages; Magnesium; Male; Mannitol; Mathematics; Methionine; Ornithine; Potassium Chloride; Pulmonary Alveoli; Rabbits; Sodium Chloride; Sucrose; Thallium; Tritium | 1971 |
[Primary structure of bovine casein. Partial sequence].
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Caseins; Cattle; Cyanogen Bromide; Glutamine; Histidine; Peptides; Phosphorus; Serine; Trypsin | 1971 |
- cross-linking sites in human and bovine fibrin.
Topics: Acetates; Amino Acid Sequence; Amino Acids; Animals; Calcium; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Dansyl Compounds; Factor XIII; Fibrin; Glutamine; Glycine; Histidine; Humans; Lysine; Macromolecular Substances; Models, Biological; Peptides; Sulfites; Thermolysin; Thioglycolates; Trypsin | 1971 |
Amino acid fermentation by Fusobacterium nucleatum.
Topics: Amino Acids; Aspartic Acid; Cysteine; Fermentation; Fusobacterium; Gingiva; Glutamates; Glutamine; Histidine; Humans; Lysine; Methionine; Mouth; Serine; Threonine | 1968 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Citrulline; Cystine; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Leukemia, Lymphoid; Lysine; Methionine; Ornithine; Phenylalanine; Prednisolone; Proline; Serine; Threonine; Triethylenemelamine; Tyrosine; Valine; Vincristine | 1971 |
Observations on the plasma amino acids of patients with acute leukemia.
Topics: Acute Disease; Alanine; Amino Acids; Asparaginase; Cytarabine; Glucocorticoids; Glutamine; Histidine; Humans; Indicators and Reagents; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methionine; Methotrexate; Nitrogen; Proline; Threonine; Vincristine | 1971 |
Amino acid requirements in vitro of human leukemic cells.
Topics: Amino Acids; Asparaginase; Asparagine; Cells, Cultured; Culture Media; Cysteine; Female; Glutamine; Histidine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Tritium; Tyrosine; Uridine | 1971 |
Degeneracy in the amino acid code.
Topics: Amino Acids; Asparagine; Bacterial Proteins; Escherichia coli; Genetic Code; Glutamine; Histidine; Leucine; Lysine; Polynucleotides; Proline; Serine; Threonine | 1966 |
[Endogenous pellagra without hyperaminoaciduria].
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Chromatography, Paper; Diagnosis, Differential; Electroencephalography; Glutamates; Glutamine; Hartnup Disease; Histidine; Humans; Lysine; Male; Pellagra; Serine; Skin Manifestations; Threonine | 1969 |
Changes in free amino acids of tomato fruit under pathogenesis.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Fruit; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Plant Diseases; Serine; Threonine; Tyrosine; Valine | 1969 |
[Determination of the biological value of dietary proteins. 13. Essential nature of arginine and histidine].
Topics: Alanine Transaminase; Arginine; Aspartate Aminotransferases; Citrates; Dietary Proteins; Eggs; Glutamates; Glutamine; Histidine; Humans; Nutritional Requirements; Quaternary Ammonium Compounds; Vegetables | 1969 |
Accumulation of 2-aminoimidazole by Streptomyces eurocidicus.
Topics: Amines; Ammonium Chloride; Anti-Bacterial Agents; Arginine; Asparagine; Chromatography, Paper; Creatine; Creatinine; Glucose; Glutamine; Glycine; Histidine; Imidazoles; Nucleosides; Spectrophotometry; Streptomyces | 1970 |
Glutamine in the phenylketonuric central nervous system.
Topics: Adolescent; Adult; Amino Acids; Biological Transport, Active; Brain; Brain Chemistry; Child; Female; Glutamine; Histidine; Humans; Intellectual Disability; Intelligence Tests; Male; Middle Aged; Phenylketonurias; Serine; Threonine; Tyrosine | 1970 |
[Amino acid composition of calf skin proteins and radiation effects].
Topics: Amino Acids; Animals; Arginine; Asparagine; Cattle; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Proteins; Radiation Effects; Serine; Skin | 1970 |
Rabbit hemoglobin. The heterogeneity of the beta-chain.
Topics: Acetates; Alleles; Amino Acids; Animals; Asparagine; Chromatography, Ion Exchange; Formates; Glutamine; Hemoglobins; Heterozygote; Histidine; Homozygote; Peptides; Pyridines; Rabbits; Serine | 1971 |
Essential amino acids for milk protein synthesis in the in vitro secretory cell and stimulation by elevated levels.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Caseins; Cattle; Culture Techniques; Cystine; Female; Glutamine; Histidine; Isoleucine; Lactation; Lactoglobulins; Leucine; Lysine; Mammary Glands, Animal; Methionine; Phenylalanine; Pregnancy; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Histidine catabolism in vitro.
Topics: Amino Acids; Animals; Autoanalysis; Brain; Carbon Isotopes; Citrulline; FIGLU Test; Glutamine; Histidine; Kidney; Liver; Muscles; Reptiles; Stimulation, Chemical; Turtles | 1968 |
High-resolution nuclear magnetic resonance spectra of selectively deuterated staphylococcal nuclease.
Topics: Amino Acids; Asparagine; Aspartic Acid; Calcium; Deoxyribonucleases; Deuterium; Glutamates; Glutamine; Histidine; Magnetic Resonance Spectroscopy; Methionine; Nucleotides; Ribonucleases; Staphylococcus; Tryptophan; Tyrosine | 1968 |
Primary structure of insoluble tendon collagen. 3. Analysis of products of tryptic digestion of native collagen.
Topics: Achilles Tendon; Alanine; Aldehydes; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Electrophoresis; Glutamine; Glycine; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Proline; Serine; Sulfur; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Trace metal requirements for malformin biosynthesis.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Aspergillus; Chromium; Cobalt; Copper; Cysteine; Glutamine; Glycine; Histidine; Iron; Isoleucine; Leucine; Lysine; Manganese; Metals; Molybdenum; Peptide Biosynthesis; Phenylalanine; Plant Growth Regulators; Proline; Serine; Trace Elements; Tryptophan; Tyrosine; Valine; Zinc | 1968 |
[On the influence of the starting position on migration of substances in paper electrophoresis].
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Asparagine; Cysteine; Electrophoresis; Glucose; Glutamates; Glutamine; Glycine; Histidine; Leucine; Lysine; Methionine; Serine; Serum Albumin; Taurine; Tryptophan | 1968 |
[The free amino acids in a water-soluble superficial film of the skin in exanthematous diseases in childhood].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chickenpox; Child; Chromatography, Paper; Female; Glutamine; Glycine; Histidine; Humans; Leucine; Male; Measles; Rubella; Scarlet Fever; Serine; Sweat; Valine | 1968 |
Amino acid metabolism in chameleons.
Topics: Alanine; Amino Acids; Animals; Arginine; Body Composition; Brain; Female; Glutamine; Glycine; Histidine; Kidney; Kinetics; Leucine; Liver; Lizards; Male; Muscles; Myocardium; Organ Specificity | 1968 |
Circadian periodicity of blood amino acids in normal and adrenalectomized mice.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Circadian Rhythm; Cystine; Densitometry; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Mice; Serine; Threonine; Tryptophan; Tryptophan Oxygenase; Tyrosine; Valine | 1969 |
[Studies on the amino acid composition of some African legumes].
Topics: Amino Acids; Arginine; Aspartic Acid; Canavanine; Chromatography; Cystine; Food Analysis; Glutamine; Glycine; Histidine; Hot Temperature; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants, Edible; Proline; Proteins; Serine; Threonine; Tryptophan; Tyrosine; Valine; Vegetables | 1969 |
Effect of histidine and certain other amino acids on the absorption of iron-59 by rats.
Topics: Amino Acids; Animals; Ascorbic Acid; Duodenum; Glutamates; Glutamine; Glycine; Histidine; Intestinal Absorption; Iron; Iron Isotopes; Lysine; Male; Methionine; Rats | 1969 |
Chemical properties of beta-lactoglobulins A, B and C.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Chromatography; Glutamates; Glutamine; Histidine; Lactoglobulins; Light; Molecular Biology; Mutation | 1964 |
Interrelation of amino acids and pH on intestinal iron absorption.
Topics: Animals; Glutamine; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Iron; Iron Isotopes; Perfusion; Rats | 1966 |
[Two dimension chromatography of ether soluble dinitrophenyl-amino acids and chromato-electrophoresis of hydracid-soluble DNP-amino acids on thin layers of powdered cellulose].
Topics: Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography, Thin Layer; Cysteine; Dinitrophenols; Electrophoresis; Glutamates; Glutamine; Histidine; Lysine | 1966 |
Active copper transport in mammalian tissues--a possible role in Wilson's disease.
Topics: Animals; Asparagine; Carcinoma, Ehrlich Tumor; Copper; Glutamine; Hepatolenticular Degeneration; Histidine; In Vitro Techniques; Kidney; Liver; Radioisotopes; Rats; Threonine | 1966 |
[Chromatographic investigation of free amino acids of the heart, kidneys and brain in experimental myocarditis].
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Brain; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Kidney; Lysine; Methionine; Myocarditis; Myocardium; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
The state of copper in human serum: evidence for an amino acid-bound fraction.
Topics: Amino Acids; Asparagine; Biological Transport; Ceruloplasmin; Copper; Glutamine; Histidine; Humans; Radioisotopes; Serum Albumin; Threonine | 1967 |
Regulation of glutamine synthetase. II. Patterns of feedback inhibition in microorganisms.
Topics: Adenine Nucleotides; Alanine; Bacteria; Cytosine Nucleotides; Eukaryota; Feedback; Fungi; Glucosamine; Glutamine; Glycine; Histidine; Ligases; Magnesium; Manganese; Tryptophan | 1967 |
Regulation of glutamine synthetase. VI. Interactions of inhibitors for Bacillus licheniformis glutamine synthetase.
Topics: Acyltransferases; Adenine Nucleotides; Alanine; Ammonium Chloride; Asparagine; Aspartic Acid; Bacillus; Carbamates; Drug Antagonism; Drug Synergism; Feedback; Glutamates; Glutamine; Glycine; Histidine; Hydroxamic Acids; Isoleucine; Kinetics; Ligases | 1967 |
Separation of Cu(II)-amino acid complexes and evidence for the existence of histidine-Cu(II)-glutamine and histidine-Cu(II)-serume complexes at physiological pH.
Topics: Amino Acids; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Copper; Glutamine; Histidine; Methods; Organometallic Compounds; Radioisotopes; Serine | 1967 |
L-histidine utilization in Aspergillus nidulans.
Topics: Ammonia-Lyases; Aspergillus nidulans; Biological Transport; Culture Media; Glutamates; Glutamic Acid; Glutamine; Histidine; Histidine Ammonia-Lyase; Nitrates; Quaternary Ammonium Compounds; Urocanic Acid | 1982 |
Hemoglobin Westmead alpha 2 122(H5)His replaced by Gln beta 2: a new hemoglobin variant with the substitution in the alpha 1 beta 1 contact area.
Topics: Adult; Amino Acids; Australia; Chromatography, Paper; Female; Fetal Hemoglobin; Genetic Variation; Globins; Glutamine; Hemoglobin A; Hemoglobins, Abnormal; Histidine; Humans; Peptides | 1980 |
Comparison of system N in fetal hepatocytes and in related cell lines.
Topics: Aging; Amino Acids; Aminoisobutyric Acids; Animals; Asparagine; Biological Transport; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Line; Ethylmaleimide; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Lithium; Liver; Liver Neoplasms; Sodium | 1983 |
Involvement of histidine and tryptophan residues of glutamine binding protein in the interaction with membrane-bound components of the glutamine transport system of Escherichia coli.
Topics: Biological Transport, Active; Cell Membrane; Diethyl Pyrocarbonate; Escherichia coli; Glutamine; Histidine; Kinetics; Tryptophan | 1983 |
Bidirectional transport of glutamine across the cell membrane in rat liver.
Topics: Amino Acids; Animals; Biological Transport; Cell Membrane; Cell Separation; Glutamine; Histidine; In Vitro Techniques; Kinetics; Liver; Rats; Sodium | 1983 |
Hemoglobin Okayama [beta 2 (NA 2) His replaced by Gln]: a new 'silent' hemoglobin variant with substituted amino acid residue at the 2,3-diphosphoglycerate binding site.
Topics: 2,3-Diphosphoglycerate; Amino Acid Sequence; Diabetes Mellitus; Diphosphoglyceric Acids; Female; Glutamine; Hemoglobins, Abnormal; Histidine; Humans; Isoelectric Focusing; Japan; Middle Aged; Oxygen | 1983 |
Hemoglobins, XLVIIII. The primary structure of a monomeric hemoglobin from the hagfish, Myxine glutinosa L.: evolutionary aspects and comparative studies of the function with special reference to the heme linkage.
Topics: Amino Acid Sequence; Animals; Biological Evolution; Fishes; Glutamine; Hagfishes; Heme; Hemoglobins; Histidine; Humans; Lampreys; Molecular Weight | 1982 |
Effects of amino acid analogues on protein degradation in isolated rat hepatocytes.
Topics: Amino Acids; Animals; Asparagine; Autophagy; Glutamine; Histidine; Leucine; Liver; Male; Phenylalanine; Proteins; Rats; Structure-Activity Relationship; Tryptophan | 1981 |
Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs.
Topics: Amino Acids; Animals; Asparagine; Biological Transport; Cells, Cultured; Choline; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lithium; Liver; Male; Rats; Sodium; Structure-Activity Relationship | 1980 |
The application of hydrogen bonding analysis in X-ray crystallography to help orientate asparagine, glutamine and histidine side chains.
Topics: Algorithms; Asparagine; Computer Simulation; Crystallography, X-Ray; Databases, Factual; Glutamine; Histidine; Hydrogen Bonding; Models, Molecular; Protein Conformation | 1995 |
Isolation and characterization of three recombinant human granulocyte colony stimulating factor His-->Gln isoforms produced in Escherichia coli.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Codon; Escherichia coli; Glutamine; Granulocyte Colony-Stimulating Factor; Histidine; Humans; Isoelectric Focusing; Mass Spectrometry; Molecular Sequence Data; Protein Engineering; Recombinant Fusion Proteins | 1993 |
Effects of aniso-osmolarity and hydroperoxides on intracellular pH in isolated rat hepatocytes as assessed by (2',7')-bis(carboxyethyl)-5(6)-carboxyfluorescein and fluorescein isothiocyanate-dextran fluorescence.
Topics: Ammonium Chloride; Animals; Barium Compounds; Cells, Cultured; Chlorides; Colchicine; Dextrans; Endocytosis; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescence Polarization; Fluorescent Dyes; Glutamine; Histidine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Liver; Lumicolchicines; Male; Osmolar Concentration; Peroxides; Raffinose; Rats; Rats, Wistar; Reactive Oxygen Species; Sodium Chloride; Spectrometry, Fluorescence; tert-Butylhydroperoxide | 1994 |
Lysine uptake by human placental microvillous membrane: comparison of system y+ with basal membrane.
Topics: Amino Acid Transport Systems; Arginine; Biological Transport; Carrier Proteins; Ethylmaleimide; Female; Glutamine; Histidine; Homoarginine; Humans; Kinetics; Leucine; Lysine; Microvilli; Placenta; Sodium | 1995 |
Functional distinction of two regions of human interleukin 6 important for signal transduction via gp130.
Topics: Alanine; Antibodies, Monoclonal; Antigens, CD; Gene Library; Genetic Testing; Glutamine; Histidine; Humans; Interleukin-6; Multiple Myeloma; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Receptors, Interleukin; Receptors, Interleukin-6; Signal Transduction; Threonine; Tumor Cells, Cultured | 1995 |
EPR studies of wild-type and several mutants of cytochrome c oxidase from Rhodobacter sphaeroides: Glu286 is not a bridging ligand in the cytochrome a3-CuB center.
Topics: Base Sequence; Copper; Cytochrome a Group; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Rhodobacter sphaeroides | 1995 |
Molecular study of the 5 alpha-reductase type 2 gene in three European families with 5 alpha-reductase deficiency.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adolescent; Amino Acid Sequence; Arginine; Asparagine; Base Sequence; Disorders of Sex Development; Exons; Female; France; Glutamine; Histidine; Humans; Introns; Male; Molecular Sequence Data; Open Reading Frames; Point Mutation; Poland; Serine | 1995 |
Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovir.
Topics: AIDS-Related Opportunistic Infections; Base Sequence; Cytomegalovirus; Drug Resistance, Microbial; Ganciclovir; Glutamine; Histidine; Humans; Molecular Sequence Data; Mutation; Phenotype; Polymerase Chain Reaction | 1995 |
Substitution of histidine-137 by glutamine abolishes the catalytic activity of the ribosome-inactivating protein alpha-sarcin.
Topics: Amino Acid Sequence; Aspergillus; Base Sequence; Catalysis; Chromatography, High Pressure Liquid; Circular Dichroism; DNA Primers; Endoribonucleases; Fungal Proteins; Glutamine; Histidine; Molecular Sequence Data; Phospholipids; Spectrophotometry, Ultraviolet | 1995 |
Evidence for separate mechanisms of cytotoxicity in mammalian cells treated with hydrogen peroxide in the absence or presence of L-histidine.
Topics: Animals; Cell Survival; CHO Cells; Colony-Forming Units Assay; Cricetinae; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Electrophoresis, Gel, Pulsed-Field; Fast Neutrons; Gamma Rays; Glutamine; Histidine; Hydrogen Peroxide | 1995 |
How do the GTPases really work?
Topics: Bacterial Proteins; Catalysis; Crystallography, X-Ray; Glutamine; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Triphosphate; Histidine; Hydrolysis; Models, Chemical; Peptide Elongation Factor Tu; Protein Conformation; Proto-Oncogene Proteins p21(ras); Protons; Structure-Activity Relationship; Thermus thermophilus; Water | 1995 |
Site-directed mutagenesis of the alpha subunit of human prolyl 4-hydroxylase. Identification of three histidine residues critical for catalytic activity.
Topics: Animals; Asparagine; Catalysis; Cell Line; Glutamine; Histidine; Humans; Mutagenesis, Site-Directed; Nucleopolyhedroviruses; Procollagen-Proline Dioxygenase; Serine; Spodoptera | 1995 |
Relevance of histidine-84 in the elongation factor Tu GTPase activity and in poly(Phe) synthesis: its substitution by glutamine and alanine.
Topics: Alanine; Amino Acid Sequence; Cloning, Molecular; Escherichia coli; Glutamine; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Histidine; Kinetics; Mutagenesis, Site-Directed; Peptide Biosynthesis; Peptide Elongation Factor Tu; Peptides; Point Mutation; Recombinant Proteins | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Residues affecting the catalysis and inhibition of rat lens aldose reductase.
Topics: Aldehyde Reductase; Animals; Binding Sites; Blotting, Western; Catalysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Lens, Crystalline; Mutagenesis, Site-Directed; NADP; Rats; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 1995 |
Perturbation of a tertiary hydrogen bond in barstar by mutagenesis of the sole His residue to Gln leads to accumulation of at least one equilibrium folding intermediate.
Topics: Bacterial Proteins; Base Sequence; DNA Primers; Glutamine; Histidine; Hydrogen Bonding; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Denaturation; Protein Folding; Protein Structure, Tertiary | 1995 |
Cold lability of the mutant forms of Escherichia coli inorganic pyrophosphatase.
Topics: Aspartic Acid; Binding Sites; Cold Temperature; Escherichia coli; Glutamic Acid; Glutamine; Histidine; Kinetics; Macromolecular Substances; Magnesium; Mutagenesis, Site-Directed; Pyrophosphatases; Structure-Activity Relationship | 1995 |
Electron spin echo envelope modulation spectroscopic analysis of altered nitrogenase MoFe proteins from Azotobacter vinelandii.
Topics: Azotobacter vinelandii; Binding Sites; Electron Spin Resonance Spectroscopy; Glutamine; Histidine; Models, Molecular; Molecular Structure; Molybdoferredoxin; Mutagenesis, Site-Directed; Nitrogenase; Protein Conformation | 1995 |
Effects of glutamine deprivation on glutamine transport and synthesis in primary culture of rat skeletal muscle.
Topics: Amino Acids; Animals; Animals, Newborn; Asparagine; Biological Transport; Cell Differentiation; Cell Division; Cells, Cultured; Cycloheximide; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Histidine; Insulin; Kinetics; Methionine Sulfoximine; Muscles; Rats; Time Factors; Tritium | 1993 |
Replacement of catalytic histidine-195 of chloramphenicol acetyltransferase: evidence for a general base role for glutamate.
Topics: Acetyl Coenzyme A; Alanine; Catalysis; Chloramphenicol; Chloramphenicol O-Acetyltransferase; Codon; Glutamates; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolysis; Molecular Structure; Mutagenesis, Site-Directed | 1994 |
Short-term starvation alters the free amino acid content of the human intestinal mucosa.
Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; Asparagine; Colon; Duodenum; Food; Glutamates; Glutamic Acid; Glutamine; Histidine; Humans; Intestinal Mucosa; Intestine, Large; Male; Starvation; Threonine; Time Factors | 1994 |
Essential role of arginine 235 in the substrate-binding of Lactobacillus plantarum D-lactate dehydrogenase.
Topics: Arginine; Base Sequence; Binding Sites; Binding, Competitive; Catalysis; Diacetyl; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lactobacillus; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Substrate Specificity | 1994 |
NMR studies of 1H resonances in the 10-18-ppm range for cytosolic aspartate aminotransferase.
Topics: Amino Acid Sequence; Animals; Aspartate Aminotransferases; Base Sequence; Cloning, Molecular; Cytosol; DNA Primers; Glutamine; Histidine; Hydrogen; Hydrogen Bonding; Lysine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Sensitivity and Specificity; Swine | 1994 |
A mechanism of proton translocation by F1F0 ATP synthases suggested by double mutants of the a subunit.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Cattle; Consensus Sequence; Escherichia coli; Glutamic Acid; Glutamine; Histidine; Kinetics; Macromolecular Substances; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Proton-Translocating ATPases; Recombinant Proteins; Restriction Mapping; Sequence Homology, Amino Acid | 1994 |
Molecular basis of a null mutation in soybean lipoxygenase 2: substitution of glutamine for an iron-ligand histidine.
Topics: Alleles; Amino Acid Sequence; Base Sequence; Blotting, Northern; DNA; Genes, Plant; Glutamine; Glycine max; Histidine; Iron; Kinetics; Lipoxygenase; Molecular Sequence Data; Oligonucleotide Probes; Point Mutation; Seeds; Sequence Homology, Amino Acid | 1994 |
Sex-specific effects of the glutamine/histidine polymorphism in apo A-IV on HDL metabolism.
Topics: Aged; Alleles; Apolipoproteins A; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Coronary Disease; Female; Gene Frequency; Glutamine; Glycoproteins; Histidine; Humans; Male; Middle Aged; Phenotype; Phosphatidylcholine-Sterol O-Acyltransferase; Polymorphism, Genetic; Sex Factors | 1994 |
Effect of taurine, L-glutamine and L-histidine addition in an amino acid glucose solution on the cellular bioavailability of zinc.
Topics: Biological Availability; Cells, Cultured; Fibroblasts; Glutamine; Histidine; Humans; Parenteral Nutrition, Total; Taurine; Zinc | 1994 |
Significance of Arg-107 and Glu-108 in the catalytic mechanism of human gamma-glutamyl transpeptidase. Identification by site-directed mutagenesis.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Blotting, Western; Catalysis; Cell Line; Chlorocebus aethiops; DNA; gamma-Glutamyltransferase; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Homology, Amino Acid; Transfection | 1993 |
The pH-dependent behavior of catalytic activities of Azospirillum brasilense glutamate synthase and iodoacetamide modification of the enzyme provide evidence for a catalytic Cys-His ion pair.
Topics: Amino Acid Sequence; Ammonia; Azospirillum brasilense; Catalysis; Cysteine; Glutamate Synthase; Glutamine; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Ketoglutaric Acids; Kinetics; Molecular Sequence Data; NADP; Sequence Analysis | 1994 |
Structural investigation of catalytically modified F120L and F120Y semisynthetic ribonucleases.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Crystallography, X-Ray; Glutamine; Histidine; Hydrogen Bonding; Lysine; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Protein Conformation; Ribonucleases; Software; Water | 1994 |
Glutamine transport in human skeletal muscle.
Topics: Asparagine; Biological Transport; Culture Media; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Ions; Kinetics; Membrane Potentials; Muscle Proteins; Muscles; Osmolar Concentration; Sarcolemma; Sodium; Substrate Specificity | 1993 |
Glutamine/histidine polymorphism in apo A-IV affects plasma concentrations of lipoprotein(a) and fibrin split products in coronary heart disease patients.
Topics: Apolipoproteins A; Coronary Disease; Fibrin Fibrinogen Degradation Products; Glutamine; Hemostasis; Histidine; Humans; Lipoprotein(a); Male; Polymorphism, Genetic; Receptors, LDL | 1993 |
Functional interactions among the His40, Glu58 and His92 catalysts of ribonuclease T1 as studied by double and triple mutants.
Topics: Catalysis; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Ribonuclease T1 | 1993 |
Determination of tumor aggressiveness in colorectal cancer by K-ras-2 analysis.
Topics: Adenocarcinoma; Aspartic Acid; Biomarkers, Tumor; Codon; Colonic Neoplasms; DNA, Neoplasm; Exons; Follow-Up Studies; Genes, ras; Glutamine; Histidine; Humans; Mutation; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Rectal Neoplasms; Retrospective Studies; Survival Rate; Valine | 1993 |
Imidazole glycerol phosphate synthase: the glutamine amidotransferase in histidine biosynthesis.
Topics: Anthranilate Synthase; Base Sequence; Catalysis; Chromatography, High Pressure Liquid; Cloning, Molecular; Escherichia coli; Gene Expression; Glutamine; Histidine; Imidazoles; Kinetics; Macromolecular Substances; Molecular Sequence Data; Nitrogenous Group Transferases; Polymerase Chain Reaction; Ribonucleotides; Transferases | 1993 |
Dissociation of hexameric Escherichia coli inorganic pyrophosphatase into trimers on His-136-->Gln or His-140-->Gln substitution and its effect on enzyme catalytic properties.
Topics: Amino Acid Sequence; Catalysis; Cloning, Molecular; Escherichia coli; Glutamine; Histidine; Inorganic Pyrophosphatase; Kinetics; Macromolecular Substances; Mathematics; Models, Structural; Models, Theoretical; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Pyrophosphatases; Recombinant Proteins | 1995 |
Mutation to glutamine of histidine 373, the catalytic base of flavocytochrome b2 (L-lactate dehydrogenase).
Topics: 2,6-Dichloroindophenol; Base Sequence; Catalysis; Electron Transport; Glutamine; Histidine; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Molecular Sequence Data; Mutagenesis, Site-Directed; Spectrometry, Fluorescence; Spectrophotometry; Titrimetry | 1995 |
Interaction of substrate uridyl 3',5'-adenosine with ribonuclease A: a molecular dynamics study.
Topics: Animals; Binding Sites; Cattle; Dinucleoside Phosphates; Glutamic Acid; Glutamine; Histidine; Kinetics; Lysine; Models, Molecular; Molecular Conformation; Protein Conformation; Ribonuclease, Pancreatic | 1995 |
Crystal structure of the complex of the variable domain of antibody D1.3 and turkey egg white lysozyme: a novel conformational change in antibody CDR-L3 selects for antigen.
Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Antigen-Antibody Complex; Binding Sites, Antibody; Chickens; Computer Graphics; Crystallography, X-Ray; Glutamine; Histidine; Hydrogen Bonding; Immunoglobulin Fragments; Immunoglobulin Variable Region; Kinetics; Mice; Models, Molecular; Muramidase; Protein Binding; Protein Conformation; Thermodynamics; Turkeys | 1996 |
The immobilized porcine pancreatic exopeptidases and its application in casein hydrolysates debittering.
Topics: Ammonium Sulfate; Animals; Arginine; Caseins; Chitin; Chromatography, High Pressure Liquid; Chymotrypsin; Decapoda; Enzymes, Immobilized; Exopeptidases; Glutamine; Glutaral; Histidine; Humans; Hydrolysis; Leucine; Lysine; Pancreas; Peptide Hydrolases; Phenylalanine; Swine; Taste; Trypsin; Tyrosine | 1996 |
Improvement of motility and fertilization potential of postthaw human sperm using glutamine.
Topics: Animals; Betaine; Cricetinae; Cryopreservation; Cryoprotective Agents; Evaluation Studies as Topic; Female; Fertilization in Vitro; Glutamine; Glycerol; Histidine; Humans; In Vitro Techniques; Male; Mesocricetus; Proline; Solutions; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa | 1996 |
Functional site in alpha-lactalbumin encompasses a region corresponding to a subsite in lysozyme and parts of two adjacent flexible substructures.
Topics: Amino Acid Sequence; Conserved Sequence; DNA Primers; Glutamic Acid; Glutamine; Histidine; Isoleucine; Kinetics; Lactalbumin; Leucine; Models, Molecular; Muramidase; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Protein Conformation; Protein Structure, Secondary; Valine | 1996 |
Site-directed mutagenesis of the formate dehydrogenase active centre: role of the His332-Gln313 pair in enzyme catalysis.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Conserved Sequence; DNA Primers; Formate Dehydrogenases; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Pseudomonas; Recombinant Proteins | 1996 |
The reaction of phosphoglycerate mutase from Schizosaccharomyces pombe with diethylpyrocarbonate.
Topics: Binding Sites; Circular Dichroism; Diethyl Pyrocarbonate; Glutamine; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Mutagenesis, Site-Directed; Phosphoglycerate Mutase; Protein Conformation; Recombinant Proteins; Schizosaccharomyces; Spectrometry, Fluorescence | 1996 |
HB Gouda [alpha 72(EF1)His-->Gln], a new silent alpha chain variant.
Topics: Amino Acid Sequence; Base Sequence; Diabetes Mellitus, Type 2; Female; Genetic Variation; Globins; Glutamine; Hemoglobins, Abnormal; Histidine; Humans; Middle Aged; Molecular Sequence Data; Mutation | 1996 |
Effect of nucleotide substrate binding on the pKa of catalytic residues in barnase.
Topics: Bacterial Proteins; Catalysis; Glutamine; Histidine; Hydrogen-Ion Concentration; Isoelectric Point; Models, Chemical; Models, Molecular; Molecular Structure; Nucleotides; Protein Conformation; Ribonucleases; Substrate Specificity; Thermodynamics | 1996 |
Effects of substitutions of the conserved histidine residues in human gamma-glutamyl transpeptidase.
Topics: Alanine; Animals; Baculoviridae; Cell Line; gamma-Glutamyltransferase; Glutamine; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Spodoptera; Structure-Activity Relationship | 1996 |
Hb Malmö [beta-97(FG-4)His-->Gln] leading to polycythemia in a Dutch family.
Topics: Adult; Female; Globins; Glutamine; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen Bonding; Male; Oxyhemoglobins; Pedigree; Point Mutation; Polycythemia; Protein Structure, Secondary | 1996 |
Gly-63-->Gln substitution adjacent to His-64 in rodent carbonic anhydrase IVs largely explains their reduced activity.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carbonic Anhydrases; Cattle; Cell Membrane; COS Cells; Gene Library; Glutamine; Glycine; Histidine; Humans; Isoenzymes; Kidney; Kinetics; Lung; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Rabbits; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Transfection | 1996 |
Histidine 265 is important for covalent catalysis by vaccinia topoisomerase and is conserved in all eukaryotic type I enzymes.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Catalysis; Conserved Sequence; DNA; DNA Topoisomerases, Type I; Glutamine; Histidine; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Vaccinia virus | 1997 |
Catalytic activities and structural properties of horseradish peroxidase distal His42 --> Glu or Gln mutant.
Topics: Catalysis; Glutamic Acid; Glutamine; Histidine; Horseradish Peroxidase; Mutagenesis, Site-Directed; Spectrum Analysis, Raman; Structure-Activity Relationship; Styrenes; Sulfides | 1997 |
Which amino-acids do serum and hemofiltrate of critically ill patients with acute renal failure contain?
Topics: Alanine; Amino Acids; Asparagine; Citrulline; Cystathionine; Ethanolamines; Extracorporeal Circulation; Glutamine; Glycine; Hemofiltration; Histidine; Humans; Kidney Failure, Chronic; Lactic Acid; Methionine; Proline | 1997 |
Mutational analysis of the role of the distal histidine and glutamine residues of prostaglandin-endoperoxide synthase-2 in peroxidase catalysis, hydroperoxide reduction, and cyclooxygenase activation.
Topics: Animals; Arachidonic Acid; Binding Sites; Catalysis; Cyclooxygenase 2; Enzyme Activation; Fatty Acids; Glutamine; Histidine; Hydrogen Peroxide; Imidazoles; Isoenzymes; Leukotrienes; Lipid Peroxides; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Peroxidases; Peroxides; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Spodoptera; Structure-Activity Relationship | 1997 |
In vivo mutational analysis of highly conserved amino acid residues of the small subunit Cpa1p of the carbamylphosphate synthetase of Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Ammonia; Ammonium Sulfate; Arginine; Aspartic Acid; Carbon-Nitrogen Ligases; Chromosome Mapping; Cysteine; Gene Expression; Glutaminase; Glutamine; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Proline; Saccharomyces cerevisiae; Sequence Analysis; Sequence Deletion; Transformation, Genetic | 1997 |
Interaction between residues Glu269 (helix VIII) and His322 (helix X) of the lactose permease of Escherichia coli is essential for substrate binding.
Topics: Anilino Naphthalenesulfonates; Biotinylation; Escherichia coli; Escherichia coli Proteins; Galactose; Glutamine; Histidine; Lactose; Membrane Transport Proteins; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Secondary; Substrate Specificity; Sulfhydryl Reagents; Symporters; Thiogalactosides | 1997 |
Trimeric inorganic pyrophosphatase of Escherichia coli obtained by directed mutagenesis.
Topics: Enzyme Stability; Escherichia coli; Glutamine; Histidine; Hydrolysis; Inorganic Pyrophosphatase; Kinetics; Magnesium Compounds; Models, Chemical; Mutagenesis, Site-Directed; Phosphates; Protein Binding; Protein Conformation; Pyrophosphatases | 1998 |
Dissecting histidine interactions of ribonuclease T1 with asparagine and glutamine replacements: analysis of double mutant cycles at one position.
Topics: Amino Acid Substitution; Asparagine; Crystallography, X-Ray; Esterification; Exoribonucleases; Glutamine; Histidine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation | 1998 |
Choroid plexus histidine transport.
Topics: Animals; Biological Transport; Choroid Plexus; Glutamine; Histidine; Hydrogen-Ion Concentration; Linear Models; Male; Rats; Rats, Sprague-Dawley | 1998 |
Hb Silver Springs [beta 131(H9)Gln-->His], a new hemoglobin variant found in six African-Americans.
Topics: Adult; Amino Acid Substitution; Black People; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Genetic Variation; Glutamine; Hemoglobins, Abnormal; Histidine; Humans; Male; Middle Aged | 1998 |
Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity.
Topics: Alanine; Animals; Bacterial Toxins; Crystallography, X-Ray; Enterotoxins; Glutamine; Histidine; Humans; Lysine; Mice; Models, Molecular; Mutation; Rabbits; Staphylococcus aureus; Superantigens; Threonine | 1998 |
Spectroscopic evidence for interaction between transmembrane helices 3 and 5 in rhodopsin.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; Cattle; Glutamic Acid; Glutamine; Histidine; Membrane Proteins; Mutagenesis, Site-Directed; Phenylalanine; Photochemistry; Protein Structure, Secondary; Rhodopsin; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Transducin | 1998 |
Transmembrane topography of subunit a in the Escherichia coli F1F0 ATP synthase.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Cell Membrane; Cysteine; Escherichia coli; Glutamine; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Proton-Translocating ATPases; Restriction Mapping; Serine; Spectrometry, Fluorescence; Sulfhydryl Reagents; Surface Properties | 1998 |
Carbamoyl phosphate synthetase: caught in the act of glutamine hydrolysis.
Topics: Asparagine; Binding Sites; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Crystallization; Crystallography, X-Ray; Dimerization; Escherichia coli; Glutamine; Histidine; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed | 1998 |
Identification of the catalytic triad of the protein D2 protease in Pseudomonas aeruginosa.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Carbapenems; Catalysis; Endopeptidases; Glutamine; Histidine; Imipenem; Ion Channels; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Porins; Pseudomonas aeruginosa; Serine | 1998 |
Effects of changes in three catalytic residues on the relative stabilities of some of the intermediates and transition states in the citrate synthase reaction.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Amino Acid Substitution; Animals; Arginine; Asparagine; Binding Sites; Catalysis; Circular Dichroism; Citrate (si)-Synthase; Citric Acid; Enzyme Stability; Glutamine; Glycine; Histidine; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Oxaloacetates; Protons; Solvents; Substrate Specificity; Swine | 1998 |
Identification of histidine 118 in the D1 polypeptide of photosystem II as the axial ligand to chlorophyll Z.
Topics: Cell Division; Chlorophyll; Cyanobacteria; Electron Spin Resonance Spectroscopy; Glutamine; Histidine; Ligands; Light-Harvesting Protein Complexes; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Spectrophotometry; Spectrum Analysis, Raman | 1998 |
Catalytic activity in Cephalosporium acremonium isopenicillin N synthase does not involve glutamine-234.
Topics: Acremonium; Amino Acid Substitution; Aspartic Acid; Binding Sites; Catalysis; Cloning, Molecular; DNA Primers; Glutamine; Histidine; Iron; Kinetics; Mutagenesis, Site-Directed; Oxidoreductases; Point Mutation; Recombinant Proteins | 1998 |
Altered regulation of platelet-derived growth factor receptor-alpha gene-transcription in vitro by spina bifida-associated mutant Pax1 proteins.
Topics: Amino Acid Substitution; Animals; Base Sequence; Carcinoma, Embryonal; DNA Primers; DNA-Binding Proteins; Gene Expression Regulation; Glutamine; Histidine; Humans; Mice; Mice, Mutant Strains; Molecular Sequence Data; Paired Box Transcription Factors; Point Mutation; Promoter Regions, Genetic; Protein Biosynthesis; Receptor, Platelet-Derived Growth Factor alpha; Receptors, Platelet-Derived Growth Factor; Recombinant Fusion Proteins; Spinal Dysraphism; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
Glutamine uptake at the blood-brain barrier is mediated by N-system transport.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Glutamine; Histidine; Hydrogen-Ion Concentration; Lithium; Male; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Sodium | 1998 |
Use of site-directed mutagenesis to identify residues specific for each reaction catalyzed by chorismate mutase-prephenate dehydrogenase from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Asparagine; Binding Sites; Catalysis; Chorismate Mutase; Circular Dichroism; Enzyme Activation; Escherichia coli; Glutamine; Histidine; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Prephenate Dehydrogenase; Recombinant Proteins | 1998 |
Effects on substrate reduction of substitution of histidine-195 by glutamine in the alpha-subunit of the MoFe protein of Azotobacter vinelandii nitrogenase.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Ammonia; Azides; Azotobacter vinelandii; Cyanides; Deuterium; Electron Transport; Glutamine; Histidine; Hydrogen; Hydrogen-Ion Concentration; Molybdoferredoxin; Nitrogen; Nitrogenase; Oxidation-Reduction; Oxidoreductases; Substrate Specificity; Temperature | 1998 |
Role of His-224 in the anomalous pH dependence of human stromelysin-1.
Topics: Glutamine; Hemopexin; Histidine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Matrix Metalloproteinase 3; Mutagenesis, Site-Directed; Peptide Fragments; Protein Conformation; Substrate Specificity | 1999 |
Evaluation of the role of His447 in the reaction catalyzed by cholesterol oxidase.
Topics: Asparagine; Binding Sites; Catalysis; Cholestenones; Cholesterol; Cholesterol Oxidase; Crystallography, X-Ray; Deuterium; Glutamine; Histidine; Hydrogen; Mutagenesis, Insertional; Oxidation-Reduction; Protein Isoforms; Solvents; Substrate Specificity | 1998 |
The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gating.
Topics: Anions; Binding, Competitive; Cations; Cell Line; Cell Membrane; Diethyl Pyrocarbonate; Electrophysiology; Glutamine; Glycine; Histidine; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Ion Channels; Membrane Potentials; Mutation, Missense; Patch-Clamp Techniques; Radioligand Assay; Receptors, Glycine; Recombinant Fusion Proteins; Reflex, Startle; Strychnine; Taurine; Tritium; Zinc | 1999 |
Role of the buried glutamate in the alpha-helical coiled coil domain of the macrophage scavenger receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Cattle; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Macrophages; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Conformation; Protein Structure, Secondary; Rabbits; Receptors, Immunologic; Receptors, Scavenger; Sequence Analysis; Valine | 1999 |
Analysis of zinc binding sites in protein crystal structures.
Topics: Aspartic Acid; Binding Sites; Catalysis; Chlorine; Crystallography, X-Ray; Cysteine; Databases, Factual; Glutamine; Histidine; Models, Molecular; Molecular Conformation; Nitrogen; Oxygen; Protein Binding; Sulfur; Zinc | 1998 |
Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
Topics: Asparagine; Binding Sites; Cholesterol Oxidase; Crystallography, X-Ray; Flavin-Adenine Dinucleotide; Glutamic Acid; Glutamine; Histidine; Models, Molecular; Mutagenesis, Site-Directed; Streptomyces; Structure-Activity Relationship; Substrate Specificity; Water | 1999 |
Transport of amino acids and ammonium in mycelium of Agaricus bisporus.
Topics: Agaricus; Amino Acids; Arginine; Biological Transport; Carbon Radioisotopes; Culture Media; Glutamic Acid; Glutamine; Histidine; Kinetics; Lysine; Methylamines; Quaternary Ammonium Compounds | 1999 |
Control of coenzyme binding to horse liver alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Animals; Arginine; Coenzymes; Computer Simulation; Glutamine; Histidine; Horses; Hydrogen-Ion Concentration; Kinetics; Liver; Lysine; Mutagenesis, Site-Directed; NAD; Protein Binding | 1999 |
Role of electrophilic and general base catalysis in the mechanism of Escherichia coli uracil DNA glycosylase.
Topics: Asparagine; Aspartic Acid; Binding Sites; Catalysis; Deuterium Oxide; DNA Glycosylases; Escherichia coli; Glutamine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Solvents; Substrate Specificity; Uracil; Uracil-DNA Glycosidase | 1999 |
Heteronuclear NMR and crystallographic studies of wild-type and H187Q Escherichia coli uracil DNA glycosylase: electrophilic catalysis of uracil expulsion by a neutral histidine 187.
Topics: Binding Sites; Carbon Isotopes; Catalysis; Crystallography, X-Ray; DNA Glycosylases; Enzyme Stability; Escherichia coli; Glutamine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protons; Substrate Specificity; Uracil; Uracil-DNA Glycosidase | 1999 |
Two new alpha chain variants: Hb Boghé [alpha58(E7)His-->Gln, alpha2], a variant on the distal histidine, and Hb CHarolles [alpha103(G10)His-Tyr, alpha1].
Topics: Amino Acid Substitution; Chromatography, High Pressure Liquid; Female; Genetic Variation; Globins; Glutamine; Hemoglobins, Abnormal; Histidine; Humans; Infant; Isoelectric Focusing; Tyrosine | 1999 |
Double heterozygosity for Hb G-San Jose [beta7(A4)Glu-->Gly] and Hb Fukuoka [beta2(NA2)His-->Tyr] in a 2 1/2-year-old girl.
Topics: Amino Acid Substitution; Child, Preschool; Female; Glutamine; Glycine; Hemoglobins, Abnormal; Heterozygote; Histidine; Humans; Point Mutation; Sequence Analysis, DNA; Tyrosine | 1999 |
The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Topics: Apoenzymes; Asparagine; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Crystallography, X-Ray; Cysteine; Escherichia coli; Glutamine; Histidine; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Peptide Fragments; Serine; Stereoisomerism | 1999 |
Engineering a thermostable protein via optimization of charge-charge interactions on the protein surface.
Topics: Amino Acid Substitution; Arginine; Asparagine; Circular Dichroism; Glutamic Acid; Glutamine; Histidine; Linear Models; Lysine; Mutagenesis, Site-Directed; Protein Engineering; Protein Folding; Static Electricity; Surface Properties; Thermodynamics; Ubiquitins | 1999 |
Mutations in the putative H-channel in the cytochrome c oxidase from Rhodobacter sphaeroides show that this channel is not important for proton conduction but reveal modulation of the properties of heme a.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Cattle; Electron Transport Complex IV; Enzyme Activation; Glutamine; Heme; Histidine; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Proton Pumps; Rhodobacter sphaeroides; Spectrum Analysis, Raman; Tyrosine | 2000 |
The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: hydration and sterochemical analysis.
Topics: Amides; Amino Acid Sequence; Animals; Anisotropy; Aspartic Acid; Binding Sites; Cattle; Crystallization; Crystallography, X-Ray; Glutamine; Histidine; Hydrogen; Hydrogen Bonding; Lysine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Ribonuclease, Pancreatic; Solvents; Sulfates; Water | 2000 |
Effects of glutamine, proline, histidine and betaine on post-thaw motility of stallion spermatozoa.
Topics: Animals; Betaine; Cryopreservation; Cryoprotective Agents; Egg Yolk; Glutamine; Glycerol; Histidine; Horses; Male; Proline; Semen Preservation; Sperm Motility | 1999 |
Investigation of spectroscopic intermediates during copper-binding and TPQ formation in wild-type and active-site mutants of a copper-containing amine oxidase from yeast.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Binding Sites; Coenzymes; Copper; Cysteine; Dihydroxyphenylalanine; Glutamic Acid; Glutamine; Histidine; Mutagenesis, Site-Directed; Oxygen Consumption; Pichia; Recombinant Proteins; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet | 2000 |
The Drosophila fl(2)d gene, required for female-specific splicing of Sxl and tra pre-mRNAs, encodes a novel nuclear protein with a HQ-rich domain.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; DNA, Complementary; Drosophila; Drosophila Proteins; Female; Genes, Insect; Glutamine; Histidine; Humans; Insect Proteins; Molecular Sequence Data; Nuclear Proteins; RNA Precursors; RNA-Binding Proteins; Transcription, Genetic | 2000 |
Manganese selectivity of pmr1, the yeast secretory pathway ion pump, is defined by residue gln783 in transmembrane segment 6. Residue Asp778 is essential for cation transport.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Aspartic Acid; ATP-Binding Cassette Transporters; Binding Sites; Calcium-Transporting ATPases; Cations, Divalent; Egtazic Acid; Fungal Proteins; Glutamine; Histidine; Ion Pumps; Manganese; Models, Molecular; Molecular Chaperones; Molecular Sequence Data; Mutation; Peptides; Phosphoproteins; Phosphorylation; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2000 |
Deterministic features of side-chain main-chain hydrogen bonds in globular protein structures.
Topics: Amino Acids; Asparagine; Aspartic Acid; Crystallization; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Protein Conformation; Protein Structure, Secondary; Proteins; Serine; Threonine | 2000 |
Identification of six CAG repeat domains into the human chromosomic region 12q24.1.
Topics: Anticipation, Genetic; Ataxins; Base Sequence; Chromosome Walking; Chromosomes, Artificial, Yeast; Chromosomes, Human, Pair 12; Cloning, Molecular; Codon; Cosmids; DNA Probes; Genetic Linkage; Glutamine; Histidine; Human Genome Project; Humans; Molecular Sequence Data; Nerve Tissue Proteins; Nervous System Diseases; Peptides; Proteins; Trinucleotide Repeat Expansion; Trinucleotide Repeats | 2000 |
Crystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricus.
Topics: Archaeal Proteins; Binding Sites; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Electrons; Escherichia coli; Glutamine; Histidine; Imidazoles; Ions; Ligands; Models, Chemical; Models, Molecular; Oxygenases; Protein Conformation; Protein Structure, Secondary; Salts; Stereoisomerism; Sulfolobus; Temperature; Threonine; Zinc | 2000 |
Pyruvate dehydrogenase kinase from Arabidopsis thaliana: a protein histidine kinase that phosphorylates serine residues.
Topics: Alanine; Amino Acid Sequence; Arabidopsis; Aspartic Acid; DNA, Complementary; Glutamine; Histidine; Histidine Kinase; Kinetics; Mitochondria; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphoamino Acids; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Trypsin; Zea mays | 2000 |
Copper catalyzed oxidation of Alzheimer Abeta.
Topics: Alzheimer Disease; Amino Acids; Amyloid beta-Peptides; Arginine; Catalysis; Chromatography, High Pressure Liquid; Copper; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen Peroxide; Iron; Oxidation-Reduction; Oxygen; Peptide Fragments; Protein Processing, Post-Translational; Time Factors; Tyrosine | 2000 |
Protection of radical intermediates at the active site of adenosylcobalamin-dependent methylmalonyl-CoA mutase.
Topics: Aerobiosis; Alanine; Binding Sites; Cobamides; Crystallization; Crystallography, X-Ray; Deuterium; Free Radicals; Glutamine; Histidine; Kinetics; Methylmalonyl-CoA Mutase; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Propionibacterium; Spectrophotometry, Ultraviolet; Spectrum Analysis; Tritium | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
The Met99Gln mutant of amicyanin from Paracoccus versutus.
Topics: Amino Acid Substitution; Bacterial Proteins; Cobalt; Disulfides; Electron Spin Resonance Spectroscopy; Electron Transport; Glutamine; Histidine; Hydrogen-Ion Concentration; Methionine; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Paracoccus; Pyridines; Recombinant Proteins; Reducing Agents; Spectrophotometry, Ultraviolet; Sulfhydryl Reagents | 2000 |
Mechanism of chalcone synthase. pKa of the catalytic cysteine and the role of the conserved histidine in a plant polyketide synthase.
Topics: Acyltransferases; Alkylating Agents; Anions; Binding Sites; Carboxy-Lyases; Catalysis; Conserved Sequence; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamine; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics; Models, Chemical; Models, Molecular; Protein Binding; Time Factors | 2000 |
Assignment of the Qy absorbance bands of photosystem II chromophores by low-temperature optical spectroscopy of wild-type and mutant reaction centers.
Topics: Bacteriochlorophylls; Benzoquinones; Cold Temperature; Cyanobacteria; Electron Spin Resonance Spectroscopy; Free Radicals; Freezing; Glutamine; Histidine; Light-Harvesting Protein Complexes; Mutagenesis, Site-Directed; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Spectrophotometry; Tyrosine | 2000 |
Importance of histidine residues for the function of the human liver UDP-glucuronosyltransferase UGT1A6: evidence for the catalytic role of histidine 370.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Catalysis; Gene Expression; Glucuronosyltransferase; Glutamine; Histidine; Humans; Kinetics; Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; Pichia; Sequence Homology, Amino Acid | 2000 |
Falsely increased HbA1c values by HPLC and falsely decreased values by immunoassay lead to identification of Hb Okayama and help in the management of a diabetic patient.
Topics: Amino Acid Substitution; Artifacts; Chromatography, High Pressure Liquid; Diabetes Mellitus; Genetic Carrier Screening; Genetic Variation; Germany; Glutamine; Glycated Hemoglobin; Hemoglobins, Abnormal; Histidine; Humans; Immunoassay; Male; Middle Aged; Polymerase Chain Reaction; Reproducibility of Results | 2000 |
Role of two histidines in the (6-4) photolyase reaction.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Deoxyribodipyrimidine Photo-Lyase; Deuterium Oxide; DNA Repair; Glutamine; Histidine; Hydrogen-Ion Concentration; Leucine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protons; Sequence Homology, Amino Acid; Substrate Specificity; Time Factors; Tryptophan; Xenopus | 2001 |
Outer sphere mutations perturb metal reactivity in manganese superoxide dismutase.
Topics: Binding Sites; Catalysis; Circular Dichroism; Computer Simulation; Conserved Sequence; Enzyme Activation; Escherichia coli; Glutamine; Histidine; Manganese; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Tyrosine | 2001 |
An essential role of Glu-243 and His-239 in the phosphotransfer reaction catalyzed by pyruvate dehydrogenase kinase.
Topics: Catalysis; Enzyme Activation; Escherichia coli; Glutamine; Histidine; Humans; Mutagenesis, Site-Directed; Point Mutation; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Recombinant Proteins; Structure-Activity Relationship | 2001 |
Characterization of an N-system amino acid transporter expressed in retina and its involvement in glutamine transport.
Topics: Acetyltransferases; Amino Acid Sequence; Amino Acid Transport System A; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Arylamine N-Acetyltransferase; Asparagine; beta-Alanine; Biological Transport; Brain; Carrier Proteins; Cell Cycle Proteins; Cloning, Molecular; Glutamine; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Mice; Molecular Sequence Data; Optic Nerve; Retina; Retinal Ganglion Cells; RNA, Messenger; Sequence Homology, Amino Acid; Sodium; Tissue Distribution; Transcription Factors | 2001 |
Mechanistic features and structure of the nitrogenase alpha-Gln195 MoFe protein.
Topics: Amino Acid Substitution; Azotobacter vinelandii; Binding Sites; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Ethylenes; Glutamine; Histidine; Hydrogen Bonding; Iron; Molybdenum; Molybdoferredoxin; Nitrogenase; Structure-Activity Relationship; Tricarboxylic Acids | 2001 |
Thermodynamics of metal ion binding. 2. Metal ion binding by carbonic anhydrase variants.
Topics: Asparagine; Binding Sites; Calorimetry; Carbonic Anhydrases; Cations, Divalent; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen Bonding; Ligands; Mutagenesis, Site-Directed; Protein Binding; Thermodynamics; Zinc | 2001 |
Active site residues of glutamate racemase.
Topics: Amino Acid Isomerases; Amino Acid Sequence; Asparagine; Aspartic Acid; Bacterial Proteins; Binding Sites; Deuterium; Glutamic Acid; Glutamine; Histidine; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Alignment | 2001 |
Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease.
Topics: Alanine; Binding Sites; Catalytic Domain; Conserved Sequence; Crystallization; Crystallography, X-Ray; Cytomegalovirus; Dimerization; Glutamic Acid; Glutamine; Histidine; Humans; Kinetics; Mutagenesis, Site-Directed; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Serine; Serine Endopeptidases; Solvents | 2001 |
Catalytic acid-base groups in yeast pyruvate decarboxylase. 1. Site-directed mutagenesis and steady-state kinetic studies on the enzyme with the D28A, H114F, H115F, and E477Q substitutions.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Carbon Dioxide; Catalysis; Catalytic Domain; Cloning, Molecular; DNA, Recombinant; Enzyme Activation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Pyruvate Decarboxylase; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity; Thiamine Pyrophosphate | 2001 |
Glutamate 170 of human l-3-hydroxyacyl-CoA dehydrogenase is required for proper orientation of the catalytic histidine and structural integrity of the enzyme.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Binding Sites; Catalysis; Crystallography, X-Ray; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Models, Molecular; Protein Binding; Time Factors | 2001 |
A method for assessing the side chain orientations of histidine, asparagine, and glutamine as well as the protonation forms of histidine in protein structures.
Topics: Aldehyde Reductase; Asparagine; beta-Lactamases; Glutamine; Histidine; Hydrogen Bonding; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Conformation; Trypsin | 2001 |
beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Chromatography; Cysteine; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myristic Acid; Plasmids; Protein Binding; Recombinant Proteins | 2001 |
Dipolar filtered 1H-13C heteronuclear correlation spectroscopy for resonance assignment of proteins.
Topics: Carbon Isotopes; Colicins; Escherichia coli Proteins; Glutamine; Glycerol; Histidine; Hydrogen; Nuclear Magnetic Resonance, Biomolecular; Proteins; Sensitivity and Specificity; Serine; Ubiquitin | 2001 |
Histidine 90 function in 4-chlorobenzoyl-coenzyme a dehalogenase catalysis.
Topics: Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Glutamine; Histidine; Hydrolases; Kinetics; Ligands; Models, Molecular; Mutation; Protein Conformation; Substrate Specificity; Time Factors | 2001 |
Interaction of acetylene and cyanide with the resting state of nitrogenase alpha-96-substituted MoFe proteins.
Topics: Acetylene; Amino Acid Substitution; Arginine; Azotobacter vinelandii; Binding Sites; Carbon Monoxide; Catalytic Domain; Cyanides; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Glutamine; Histidine; Leucine; Molybdoferredoxin; Nitrogenase; Substrate Specificity; Thermodynamics | 2001 |
Active site mutations in CheA, the signal-transducing protein kinase of the chemotaxis system in Escherichia coli.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Binding, Competitive; Chemotaxis; Escherichia coli; Escherichia coli Proteins; Genetic Complementation Test; Glutamine; Histidine; Histidine Kinase; Kinetics; Magnesium; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Mutagenesis, Site-Directed; Phosphorylation; Polymerase Chain Reaction; Protein Kinases; Signal Transduction | 2001 |
Site-directed mutagenesis reveals the essentiality of the conserved residues in the putative diiron active site of the trypanosome alternative oxidase.
Topics: Amino Acid Motifs; Animals; Binding Sites; Cell Division; Escherichia coli; Genetic Complementation Test; Glutamine; Heme; Histidine; Immunoblotting; Iron; Models, Genetic; Mutagenesis, Site-Directed; Mutation; Oxidoreductases; Plasmids; Protein Binding; Protein Structure, Tertiary; Trypanosoma brucei brucei | 2002 |
Disparate binding of chaperone proteins by HLA-A subtypes.
Topics: Antiporters; Aspartic Acid; Blotting, Western; Cell Line; Flow Cytometry; Glutamine; Histidine; HLA-A Antigens; Humans; Immunoglobulins; Membrane Transport Proteins; Models, Molecular; Molecular Chaperones; Protein Binding; Protein Conformation; Structure-Activity Relationship; Substrate Specificity; Transfection | 2002 |
Role of T7 RNA polymerase His784 in start site selection and initial transcription.
Topics: Alanine; Bacteriophage T7; Base Sequence; Binding Sites; DNA-Directed RNA Polymerases; Glutamine; Guanosine; Guanosine Triphosphate; Histidine; Hydrogen Bonding; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Stereoisomerism; Transcription Initiation Site; Viral Proteins | 2002 |
Evaluation by mutagenesis of the roles of His309, His315, and His319 in the coenzyme site of pig heart NADP-dependent isocitrate dehydrogenase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Circular Dichroism; Escherichia coli; Ferrous Compounds; Glutamine; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; NADP; Phenylalanine; Protein Structure, Secondary; Recombinant Proteins; Substrate Specificity; Swine | 2002 |
Effects of amino acid substitutions at beta 131 on the structure and properties of hemoglobin: evidence for communication between alpha 1 beta 1- and alpha 1 beta 2-subunit interfaces.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; Cysteine; Globins; Glutamine; Hemoglobin A; Histidine; Humans; Hydrogen Bonding; Mercuribenzoates; Nuclear Magnetic Resonance, Biomolecular; Oxygen; Protein Conformation; Protons; Recombinant Proteins; Structure-Activity Relationship; Sulfhydryl Reagents | 2002 |
Structure-based mutational and functional analysis identify human NM23-H2 as a multifunctional enzyme.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Binding Sites; Catalysis; DNA; DNA-Binding Proteins; Glutamine; Histidine; Humans; Hydrolysis; Monomeric GTP-Binding Proteins; Multienzyme Complexes; Mutagenesis, Site-Directed; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Structure-Activity Relationship; Transcription Factors | 2002 |
Enthalpic homogeneous pair interaction coefficients of L-alpha-amino acids as a hydrophobicity parameter of amino acid side chains.
Topics: Amino Acids; Arginine; Asparagine; Calorimetry; Cysteine; Glutamic Acid; Glutamine; Histidine; Solutions; Stereoisomerism; Thermodynamics; Tryptophan; Water | 2002 |
The carbon monoxide derivative of human hemoglobin carrying the double mutation LeuB10-->Tyr and HisE7-->Gln on alpha and beta chains probed by infrared spectroscopy.
Topics: Amino Acid Substitution; Carbon Monoxide; Carboxyhemoglobin; Glutamine; Heme; Hemoglobin A; Histidine; Humans; Hydrogen Bonding; Iron; Kinetics; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Tyrosine | 2002 |
The 1.35 A structure of cadmium-substituted TM-3, a snake-venom metalloproteinase from Taiwan habu: elucidation of a TNFalpha-converting enzyme-like active-site structure with a distorted octahedral geometry of cadmium.
Topics: ADAM Proteins; ADAM17 Protein; Amino Acid Sequence; Animals; Binding Sites; Cadmium; Collagenases; Crotalid Venoms; Crystallography, X-Ray; Disulfides; Electrons; Glutamine; Histidine; Ligands; Metalloendopeptidases; Models, Molecular; Models, Statistical; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Snake Venoms; Tumor Necrosis Factor-alpha; Viperidae | 2002 |
Mutational, kinetic, and NMR studies of the mechanism of E. coli GDP-mannose mannosyl hydrolase, an unusual Nudix enzyme.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Catalysis; DNA Mutational Analysis; Escherichia coli Proteins; Glutamic Acid; Glutamine; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Nudix Hydrolases; Osmolar Concentration; Protons; Pyrophosphatases; Temperature | 2002 |
X-ray structure of two crystalline forms of a streptomycete ribonuclease with cytotoxic activity.
Topics: Amino Acid Sequence; Arginine; Asparagine; Binding Sites; Dose-Response Relationship, Drug; Glutamine; Histidine; Humans; Isoenzymes; K562 Cells; Models, Molecular; Molecular Sequence Data; Protein Conformation; Ribonucleases; Sequence Homology, Amino Acid; Streptomyces aureofaciens; Temperature; Tumor Cells, Cultured; X-Ray Diffraction | 2002 |
Histidine 190-D1 and glutamate 189-D1 provide structural stabilization in photosystem II.
Topics: Amino Acid Substitution; Cyanobacteria; Electron Spin Resonance Spectroscopy; Glutamine; Histidine; Kinetics; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Recombinant Proteins; Spectrometry, Fluorescence | 2002 |
Influence of the protein environment on the properties of a tyrosyl radical in reaction centers from Rhodobacter sphaeroides.
Topics: Arginine; Dimerization; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Light-Harvesting Protein Complexes; Models, Molecular; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Rhodobacter sphaeroides; Spectrophotometry; Spectroscopy, Near-Infrared; Tyrosine | 2002 |
The crystal structure of the H48Q active site mutant of human group IIA secreted phospholipase A2 at 1.5 A resolution provides an insight into the catalytic mechanism.
Topics: Anions; Asparagine; Binding Sites; Catalysis; Cations, Divalent; Cell Membrane; Cobalt; Crystallization; Crystallography, X-Ray; Glutamine; Group II Phospholipases A2; Histidine; Humans; Hydrolysis; Micrococcus luteus; Mutagenesis, Site-Directed; Nickel; Phosphatidylglycerols; Phospholipases A; Phospholipases A2; Recombinant Proteins; Substrate Specificity | 2002 |
Breaking symmetry: mutations engineered into R67 dihydrofolate reductase, a D2 symmetric homotetramer possessing a single active site pore.
Topics: Amino Acid Substitution; Binding Sites; Circular Dichroism; Gene Dosage; Genes, Bacterial; Genes, Synthetic; Glutamine; Histidine; Kinetics; Molecular Mimicry; Mutagenesis, Site-Directed; NADP; R Factors; Tandem Repeat Sequences; Tetrahydrofolate Dehydrogenase | 2002 |
Changes in stability upon charge reversal and neutralization substitution in staphylococcal nuclease are dominated by favorable electrostatic effects.
Topics: Amino Acid Substitution; Aspartic Acid; Enzyme Stability; Glutamic Acid; Glutamine; Guanidine; Histidine; Hydrogen-Ion Concentration; Lysine; Micrococcal Nuclease; Models, Chemical; Normal Distribution; Poisson Distribution; Protein Denaturation; Protein Folding; Static Electricity; Surface Properties; Thermodynamics | 2003 |
Cytotoxic activity of nucleoside diphosphate kinase secreted from Mycobacterium tuberculosis.
Topics: Adenine; Adenosine Triphosphate; Blotting, Western; Cell Death; Cloning, Molecular; DNA Primers; DNA, Bacterial; Escherichia coli; Glutamine; GTP Phosphohydrolases; Histidine; Macrophages; Mutagenesis, Site-Directed; Mutation; Mycobacterium tuberculosis; Nucleoside-Diphosphate Kinase; Phosphorylation; Plasmids; Polymerase Chain Reaction; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2X7 | 2003 |
Characterization of metal ligand mutants of tyrosine hydroxylase: insights into the plasticity of a 2-histidine-1-carboxylate triad.
Topics: Amino Acid Motifs; Animals; Binding Sites; Carboxylic Acids; Catalysis; Dopamine; Glutamic Acid; Glutamine; Histidine; Iron; Kinetics; Ligands; Mutagenesis, Site-Directed; Protein Binding; Rats; Tyrosine 3-Monooxygenase | 2003 |
RNA recognition motif-type RNA-binding proteins in Trypanosoma cruzi form a family involved in the interaction with specific transcripts in vivo.
Topics: 3' Untranslated Regions; 5' Untranslated Regions; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Blotting, Southern; DNA; DNA Restriction Enzymes; Glutamine; Glycine; Histidine; Molecular Sequence Data; Phylogeny; Poly G; Poly U; Protein Structure, Secondary; Protozoan Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA-Binding Proteins; RNA, Messenger; Sequence Alignment; Trypanosoma cruzi | 2003 |
Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation.
Topics: Acetic Acid; Alanine; Animals; Astrocytes; beta-Alanine; Biological Transport; Carbon Isotopes; Cell Compartmentation; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Humans; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Neuroblastoma; Rats | 2003 |
Thioredoxin motif of Caenorhabditis elegans PDI-3 provides Cys and His catalytic residues for transglutaminase activity.
Topics: Amino Acid Motifs; Animals; Caenorhabditis elegans Proteins; Catalytic Domain; Cysteine; Glutamine; Histidine; Mutagenesis, Site-Directed; Protein Disulfide-Isomerases; Recombinant Proteins; Thioredoxins; Transglutaminases | 2003 |
An identical mutation carried by different genes: Hb Frankfurt [alpha50(CE8)His->Gln].
Topics: Aged; Amino Acid Substitution; Base Sequence; Female; Glutamine; Hemoglobins, Abnormal; Histidine; Humans; Mutation | 2003 |
Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-onset Alzheimer's disease.
Topics: Adult; Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Peptides; Blotting, Western; Brain; DNA Mutational Analysis; Enzyme-Linked Immunosorbent Assay; Family Health; Female; Glutamine; Histidine; Humans; Immunohistochemistry; Membrane Proteins; Mutation, Missense; Pedigree; Peptide Fragments; Plaque, Amyloid; Presenilin-1; Serine; Tyrosine | 2003 |
Bacterial expression, purification, and characterization of rat kidney-type mitochondrial glutaminase.
Topics: Animals; Blotting, Western; Chromatography, Affinity; Chromatography, Gel; Cloning, Molecular; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Escherichia coli; Exons; Gene Deletion; Gene Expression; Genetic Vectors; Glutamate Dehydrogenase; Glutaminase; Glutamine; Histidine; Isopropyl Thiogalactoside; Kinetics; Mitochondria; Oligopeptides; Phosphates; Polymerase Chain Reaction; Protein Binding; Protein Structure, Quaternary; Rats; Recombinant Proteins; Sonication | 2003 |
Growth of Listeria monocytogenes in defined media.
Topics: Alanine; Arginine; Asparagine; Culture Media; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Listeria monocytogenes; Methionine; Proteins; Valine | 1961 |
STUDIES ON COLLETOTRICHUM CAPSICI III. THE EFFECT OF INITIAL PH ON THE GROWTH AND AMINO ACID COMPOSITION.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Chromatography; Colletotrichum; Cysteine; Fungi; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Phenylalanine; Research; Serine; Tyrosine | 1963 |
EFFECT OF ALANINE AND THREONINE ON THE SYNTHESIS OF SERINE BY LEUCONOSTOC MESENTEROIDES.
Topics: Alanine; Amino Acids; Bacterial Proteins; Benzoates; Formates; Glutamine; Glycine; Histidine; Leuconostoc; Leucovorin; Proteins; Research; Serine; Threonine | 1963 |
THE SOLUBILITY OF AMINO ACIDS AND RELATED COMPOUNDS IN AQUEOUS UREA SOLUTIONS.
Topics: Alanine; Amino Acids; Asparagine; Chemical Phenomena; Chemistry; Glutamine; Glycine; Histidine; Leucine; Methionine; Peptides; Phenylalanine; Research; Solubility; Solvents; Spectrophotometry; Threonine; Tryptophan; Tyrosine; Urea | 1963 |
EXTRACTIVES FROM MUSCLE MEAT OF BALAENOPTERA PHYSALUS (LINNAEUS).
Topics: Alanine; Animals; Cetacea; Chromatography; Creatine; Creatinine; Dipeptides; Fin Whale; Glutamine; Glycine; Guanidines; Histidine; Infrared Rays; Inositol; Meat; Muscles; Picrates; Purines; Research; Taurine; Tissue Extracts | 1963 |
THE ELECTRON MICROSCOPIC LOCALIZATION OF THE NEUTRAL SOLUBLE PROTEINS OF DEVELOPING BOVINE ENAMEL.
Topics: Amino Acids; Animals; Cattle; Dental Calculus; Dental Enamel; Electrons; Embryology; Glutamine; Glycine; Histidine; Histocytochemistry; Microscopy; Microscopy, Electron; Proline; Proteins; Research; Serine | 1964 |
NUTRITIONAL FACTORS RELATING TO GROWTH AND OXYTETRACYCLINE FORMATION BY STREPTOMYCES RIMOSUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Cysteine; Cystine; Glutamine; Glycine; Histidine; Isoleucine; Lysine; Metabolism; Methionine; Oxytetracycline; Research; Serine; Streptomyces; Streptomyces rimosus | 1964 |
STUDIES ON THE HYDROLYTIC ACTION OF PRONASE ON DERIVATIZED AND NON-DERIVATIZED PROTEINS.
Topics: Alanine; Arginine; Asparagine; Cystine; Dinitrophenols; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptide Hydrolases; Phenylalanine; Proline; Pronase; Proteins; Research; Ribonucleases; Streptomyces; Threonine; Tyrosine; Valine | 1964 |
URINARY TRYPTAMINE AND INDOLE-3-ACETIC ACID EXCRETION BY SCHIZOPHRENIC PATIENTS: USE OF THE TRYPTAMINE/INDOLE ACETIC ACID RATIO AS AN INDEX OF MONOAMINE OXIDASE INHIBITION.
Topics: Amino Acids; Fluids and Secretions; Glutamine; Glycine; Histidine; Humans; Indoleacetic Acids; Indoles; Iproniazid; Metabolism; Methionine; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pharmacology; Phenylalanine; Schizophrenia; Tryptamines; Tryptophan; Urine | 1964 |
CHANGES IN THE NERVE CELL PROTEINS IN DOGS DURING RESUSCITATION FROM THE STATE OF CLINICAL DEATH.
Topics: Alanine; Aminobutyrates; Ammonia; Arginine; Asparagine; Brain Chemistry; Cerebral Cortex; Cystine; Death; Dogs; Glutamates; Glutamine; Glycine; Histidine; Histocytochemistry; Hypothermia; Hypothermia, Induced; Leucine; Lysine; Methionine; Nerve Tissue Proteins; Neurons; Pathology; Phenylalanine; Proteins; Research; Resuscitation; Serine | 1965 |
Contribution of active site residues to the activity and thermal stability of ribonuclease Sa.
Topics: Arginine; Calorimetry, Differential Scanning; Catalysis; Catalytic Domain; Dinucleoside Phosphates; Enzyme Stability; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Mutagenesis, Site-Directed; Poly I; Recombinant Proteins; Ribonucleases; Substrate Specificity; Thermodynamics | 2003 |
Mutagenesis of putative catalytic and regulatory residues of Streptomyces chromofuscus phospholipase D differentially modifies phosphatase and phosphodiesterase activities.
Topics: Acid Phosphatase; Amino Acid Sequence; Aspartic Acid; Binding Sites; Calcium; Calorimetry; Catalytic Domain; Circular Dichroism; Glutamine; Glycoproteins; Histidine; Hydrolysis; Ions; Iron; Kinetics; Magnesium; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Sequence Data; Mutation; Phospholipase D; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry; Streptomyces; Time Factors; Ultraviolet Rays | 2003 |
Lecithin retinol acyltransferase is a founder member of a novel family of enzymes.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalytic Domain; Conserved Sequence; Cysteine; Cysteine Endopeptidases; Glutamine; Histidine; Humans; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Phosphatidylcholine-Sterol O-Acyltransferase | 2003 |
Dissecting structural and electrostatic interactions of charged groups in alpha-sarcin. An NMR study of some mutants involving the catalytic residues.
Topics: Amino Acid Substitution; Aspergillus; Binding Sites; Catalytic Domain; Endoribonucleases; Fungal Proteins; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Models, Chemical; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Protons; Static Electricity | 2003 |
1H NMR studies of the effect of mutation at Valine45 on heme microenvironment of cytochrome b5.
Topics: Animals; Cattle; Cytochromes b5; Enzyme Stability; Glutamine; Heme; Histidine; Imidazoles; Ligands; Magnetic Resonance Spectroscopy; Microsomes; Molecular Structure; Mutation; Protein Conformation; Temperature; Tyrosine; Valine | 2003 |
Mutant R1 proteins from Escherichia coli class Ia ribonucleotide reductase with altered responses to dATP inhibition.
Topics: Adenosine Triphosphate; Allosteric Site; Asparagine; Binding Sites; Cell Division; Dose-Response Relationship, Drug; Escherichia coli; Glutamine; Histidine; Hydrogen Bonding; Kinetics; Magnesium; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Plasmids; Protein Binding; Ribonucleotide Reductases; Substrate Specificity; Surface Plasmon Resonance | 2004 |
Enzymatic mechanism of low-activity mouse alcohol dehydrogenase 2.
Topics: Alanine; Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Benzyl Alcohol; Catalysis; Deuterium Exchange Measurement; Enzyme Activation; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Mice; Mutagenesis, Site-Directed; Proline; Recombinant Proteins; Substrate Specificity | 2004 |
The role of Tyr41 and His155 in the functional properties of superoxide dismutase from the archaeon Sulfolobus solfataricus.
Topics: Amino Acid Substitution; Archaeal Proteins; Crystallization; Crystallography, X-Ray; Enzyme Activation; Enzyme Inhibitors; Enzyme Stability; Glutamine; Histidine; Hot Temperature; Phenylalanine; Protein Denaturation; Recombinant Proteins; Sodium Dodecyl Sulfate; Sulfolobus; Superoxide Dismutase; Tyrosine | 2004 |
Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Catalytic Domain; Crystallography, X-Ray; Deuterium Exchange Measurement; Glutamine; Histidine; Horses; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Liver; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; NAD | 2004 |
Mutagenic studies on histidine 98 of methylglyoxal synthase: effects on mechanism and conformational change.
Topics: Allosteric Regulation; Amino Acid Substitution; Asparagine; Carbon-Oxygen Lyases; Crystallography, X-Ray; Deuterium Exchange Measurement; Deuterium Oxide; Dihydroxyacetone Phosphate; Enzyme Inhibitors; Escherichia coli Proteins; Glutamine; Glycolates; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Insertional; Protein Conformation; Recombinant Proteins; Substrate Specificity; Thermodynamics | 2004 |
Thalassemia intermedia due to co-inheritance of beta0/beta(+)-thalassemia and (- -SEA) alpha-thalassemia/Hb Westmead [alpha122(H5)His > Gln (alpha2)] in a Chinese family.
Topics: Adult; alpha-Thalassemia; Asian People; beta-Thalassemia; China; Codon; DNA Mutational Analysis; Family; Genotype; Globins; Glutamine; Hemoglobins, Abnormal; Histidine; Humans; Inclusion Bodies; Male; Phenotype; Sequence Deletion | 2004 |
Action of Pasteurella multocida toxin depends on the helical domain of Galphaq.
Topics: Amino Acid Sequence; Animals; Asparagine; Bacterial Proteins; Bacterial Toxins; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Genetic Vectors; Glutamine; GTP-Binding Protein alpha Subunits, Gq-G11; Histidine; Inositol Phosphates; Isoenzymes; Mice; Mice, Knockout; Molecular Sequence Data; Mutation; Phospholipase C beta; Plasmids; Protein Structure, Tertiary; Recombinant Fusion Proteins; Retroviridae; Signal Transduction; Type C Phospholipases | 2004 |
Molecular mapping of the thrombin-heparin cofactor II complex.
Topics: Alanine; Allosteric Site; Binding Sites; Dermatan Sulfate; Dose-Response Relationship, Drug; Glutamine; Glycosaminoglycans; Heparin Cofactor II; Histidine; Humans; Kinetics; Lysine; Models, Molecular; Mutagenesis; Mutation; Protein Binding; Structure-Activity Relationship; Thrombin; Time Factors; Tyrosine | 2004 |
Negatively charged residues and hydrogen bonds tune the ligand histidine pKa values of Rieske iron-sulfur proteins.
Topics: Animals; Aspartic Acid; Burkholderia; Cattle; Computer Simulation; Electron Transport Complex III; Ferredoxins; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Iron-Sulfur Proteins; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Rhodobacter sphaeroides; Static Electricity; Thermodynamics; Titrimetry | 2004 |
ECEPE proteins: a novel family of eukaryotic cysteine proteinases.
Topics: Amino Acid Sequence; Aspartic Acid; Catalysis; Cysteine; Cysteine Endopeptidases; Eukaryotic Cells; Glutamine; Guanylate Cyclase; Histidine; Molecular Sequence Data; Papain; Sequence Homology, Amino Acid | 2004 |
Polyprotein cleavage mechanism of SARS CoV Mpro and chemical modification of the octapeptide.
Topics: Amino Acid Sequence; Binding Sites; Computer Simulation; Coronavirus 3C Proteases; Cysteine; Cysteine Endopeptidases; Drug Design; Glutamine; Histidine; Hydrogen Bonding; Models, Molecular; Molecular Biology; Molecular Structure; Peptides; Protein Conformation; Protein Structure, Tertiary; Quantum Theory; Serine; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Static Electricity | 2004 |
The glutamine residue of the conserved GGQ motif in Saccharomyces cerevisiae release factor eRF1 is methylated by the product of the YDR140w gene.
Topics: Amino Acid Motifs; Amino Acid Sequence; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamine; Guanosine Triphosphate; Histidine; Mass Spectrometry; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Peptide Termination Factors; Plasmids; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
Insights into redox partner interactions and substrate binding in nitrite reductase from Alcaligenes xylosoxidans: crystal structures of the Trp138His and His313Gln mutants.
Topics: Alcaligenes; Azurin; Binding Sites; Copper; Crystallography, X-Ray; Glutamine; Histidine; Mutagenesis, Site-Directed; Mutation; Nitrite Reductases; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Time Factors; Tryptophan; Water | 2004 |
Analysis of glutamine accumulation in rat brain mitochondria in the presence of a glutamine uptake inhibitor, histidine, reveals glutamine pools with a distinct access to deamidation.
Topics: Amides; Animals; Arginine; Brain Chemistry; Cerebral Cortex; Glutamic Acid; Glutamine; Hippocampus; Histidine; Lysine; Male; Mitochondria; Rats | 2004 |
Association of apo A-IV 360 (Gln --> His) polymorphism with plasma lipids and lipoproteins: the Framingham Offspring Study.
Topics: Adult; Apolipoproteins A; Arteriosclerosis; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Female; Glutamine; Histidine; Humans; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; Triglycerides | 2005 |
The conserved histidine 295 does not contribute to proton cotransport by the glutamate transporter EAAC1.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Animals; Biological Transport, Active; Cell Line; Conserved Sequence; Cysteine; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Chemical; Patch-Clamp Techniques; Protons; Rats; Symporters; Transfection | 2005 |
Hinge residue Ile260 of DNA polymerase beta is important for enzyme activity and fidelity.
Topics: Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; DNA Polymerase beta; Enzyme Activation; Enzyme Stability; Escherichia coli Proteins; Genetic Complementation Test; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Isoleucine; Lysine; Peptide Fragments; Phenotype; Protein Folding; Protein Structure, Tertiary; Rats; Substrate Specificity | 2005 |
Site-directed mutagenesis of active site residues of phosphite dehydrogenase.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Cysteine; Deuterium Exchange Measurement; Diethyl Pyrocarbonate; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; Phosphites; Sequence Alignment | 2005 |
Identification of key amino acids responsible for the substantially higher affinities of human type 1 3beta-hydroxysteroid dehydrogenase/isomerase (3beta-HSD1) for substrates, coenzymes, and inhibitors relative to human 3beta-HSD2.
Topics: 3-Hydroxysteroid Dehydrogenases; Allosteric Site; Amino Acid Sequence; Androstenols; Animals; Arginine; Baculoviridae; Blotting, Western; Catalysis; Catalytic Domain; Cell Line; Dihydrotestosterone; DNA Primers; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutamine; Histidine; Humans; Insecta; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NAD; Protein Binding; Protein Conformation; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity; Tissue Distribution | 2005 |
15N/14N position-specific isotopic analyses of polynitrogenous amino acids.
Topics: Amino Acids; Asparagine; Gas Chromatography-Mass Spectrometry; Glutamine; Histidine; Lysine; Nitrogen Isotopes; Reproducibility of Results | 2005 |
H662 is the linchpin of ATP hydrolysis in the nucleotide-binding domain of the ABC transporter HlyB.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Substitution; ATP-Binding Cassette Transporters; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Glutamine; Hemolysin Proteins; Histidine; Hydrogen Bonding; Hydrolysis; Models, Molecular; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Structure-Activity Relationship | 2005 |
A novel A*24 allele, A*2442, was detected through routine bone marrow donor screening.
Topics: Alleles; Asparagine; Base Sequence; Bone Marrow; DNA Primers; Exons; Female; Glutamine; Heterozygote; Histidine; HLA-A Antigens; HLA-A24 Antigen; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Homology, Nucleic Acid; Tissue Banks; Tissue Donors | 2005 |
The EAL domain protein VieA is a cyclic diguanylate phosphodiesterase.
Topics: Bacterial Proteins; Cations, Divalent; Escherichia coli Proteins; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Osmolar Concentration; Phosphoric Diester Hydrolases; Phosphorus-Oxygen Lyases; Protein Structure, Tertiary; Second Messenger Systems; Temperature; Vibrio cholerae | 2005 |
Characterization of adducts formed between human serum albumin and the butadiene metabolite epoxybutanediol.
Topics: Amino Acid Sequence; Butadienes; Chromatography, Liquid; Epoxy Compounds; Glutamine; Histidine; Humans; Lysine; Mass Spectrometry; Molecular Sequence Data; Serum Albumin; Trypsin | 2005 |
Localization of a substrate binding domain of the human reduced folate carrier to transmembrane domain 11 by radioaffinity labeling and cysteine-substituted accessibility methods.
Topics: Amino Acid Sequence; Anions; Aspartic Acid; Blotting, Western; Cell Line; Cell Membrane; Cysteine; Cytosol; Folic Acid; Glutamine; HeLa Cells; Histidine; Humans; K562 Cells; Leucovorin; Membrane Transport Proteins; Mesylates; Microscopy, Fluorescence; Molecular Sequence Data; Mutagenesis; Mutation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Reduced Folate Carrier Protein; Sulfhydryl Reagents; Temperature; Thiocyanates; Time Factors; Transfection; Tyrosine | 2005 |
Acrylamide stimulates glutamine uptake in Fischer 344 rat astrocytes by a mechanism involving upregulation of the amino acid transport system N.
Topics: Acrylamide; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Astrocytes; Cells, Cultured; Glutamine; Histidine; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2005 |
In silico analysis of ORF1ab in coronavirus HKU1 genome reveals a unique putative cleavage site of coronavirus HKU1 3C-like protease.
Topics: Amino Acid Sequence; Amino Acid Substitution; Computational Biology; Coronavirus; Coronavirus 3C Proteases; Cysteine Endopeptidases; Glutamine; Histidine; Models, Molecular; Molecular Sequence Data; Open Reading Frames; Point Mutation; Protein Structure, Tertiary; Sequence Alignment; Viral Proteins | 2005 |
MMP20 active-site mutation in hypomaturation amelogenesis imperfecta.
Topics: Adenine; Amelogenesis Imperfecta; Binding Sites; Conserved Sequence; Dental Enamel Proteins; Female; Gene Expression Regulation, Enzymologic; Gene Frequency; Genes, Recessive; Genetic Heterogeneity; Glutamine; Histidine; Humans; Kallikreins; Male; Matrix Metalloproteinase 20; Matrix Metalloproteinases; Mutation; Mutation, Missense; Pedigree; Thymine | 2005 |
Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression.
Topics: Alleles; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Blotting, Northern; Cell Cycle Proteins; Cell Nucleus; Dimerization; Gene Expression Regulation, Fungal; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Green Fluorescent Proteins; Histidine; Intracellular Signaling Peptides and Proteins; Membrane Transport Proteins; Microscopy, Fluorescence; Mitochondria; Models, Biological; Models, Genetic; Mutation; Nitrogen; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Protein Transport; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Transcription, Genetic | 2005 |
His374 of wheat endoxylanase inhibitor TAXI-I stabilizes complex formation with glycoside hydrolase family 11 endoxylanases.
Topics: Alanine; Amino Acid Substitution; Aspergillus niger; Bacillus subtilis; Circular Dichroism; Endo-1,4-beta Xylanases; Glutamine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Pichia; Plant Proteins; Protein Binding; Recombinant Proteins; Surface Plasmon Resonance; Trichoderma; Triticum | 2005 |
Interactions of GTP with the ATP-grasp domain of GTP-specific succinyl-CoA synthetase.
Topics: Adenosine Triphosphate; Animals; Arginine; Binding Sites; Crystallography, X-Ray; Glutamine; Guanine; Guanosine Triphosphate; Histidine; Hydrolysis; Models, Molecular; Nitrogen; Phosphates; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Conformation; Protein Isoforms; Ribose; Succinate-CoA Ligases; Swine | 2006 |
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B).
Topics: Adaptor Proteins, Signal Transducing; Aged; alpha-Synuclein; Amyotrophic Lateral Sclerosis; Brain; DNA Mutational Analysis; Endosomal Sorting Complexes Required for Transport; Glial Fibrillary Acidic Protein; Glutamine; Histidine; Humans; Immunohistochemistry; Isoleucine; Male; Mutation; Nerve Tissue Proteins; Neurofilament Proteins; Phenotype; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequestosome-1 Protein; Spinal Cord; tau Proteins; Ubiquitin; Valine | 2006 |
Engineering ATPase activity in the isolated ABC cassette of human TAP1.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP-Binding Cassette Transporters; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Engineering; Protein Structure, Tertiary; Sequence Homology, Amino Acid | 2006 |
Catalytic site modifications of TAP1 and TAP2 and their functional consequences.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP Binding Cassette Transporter, Subfamily B, Member 3; ATP-Binding Cassette Transporters; Baculoviridae; Binding Sites; Catalytic Domain; Cell Line, Tumor; Genetic Vectors; Glutamic Acid; Glutamine; Histidine; Humans; Nucleotides; Protein Transport | 2006 |
Functional P2X7 receptor polymorphisms (His155Tyr, Arg307Gln, Glu496Ala) in patients with Crohn's disease.
Topics: Alanine; Amino Acid Substitution; Arginine; Case-Control Studies; Crohn Disease; Female; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Histidine; Humans; Male; Polymorphism, Single Nucleotide; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Tyrosine | 2007 |
Inhibition of glutamine transport into mitochondria protects astrocytes from ammonia toxicity.
Topics: Adenosine Triphosphate; Ammonia; Animals; Astrocytes; Cells, Cultured; Glutamine; Histidine; Mitochondria; Permeability; Rats; Reactive Oxygen Species | 2007 |
A novel mutation in GCH-1 gene in a case of dopa-responsive dystonia.
Topics: Adolescent; Dihydroxyphenylalanine; DNA Mutational Analysis; Dopamine Agents; Dystonia; Family Health; Female; Glutamine; GTP Cyclohydrolase; Histidine; Humans; Mutation | 2007 |
Modulation of heme redox potential in the cytochrome c6 family.
Topics: Amino Acid Sequence; Crystallography, X-Ray; Cyanobacteria; Cytochromes c6; Electrochemistry; Electron Transport; Glutamine; Heme; Histidine; Hydrogen-Ion Concentration; Iron; Ligands; Methionine; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Valine | 2007 |
How can a single second sphere amino acid substitution cause reduction midpoint potential changes of hundreds of millivolts?
Topics: Amino Acid Substitution; Binding Sites; Circular Dichroism; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Ferric Compounds; Ferrous Compounds; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Structure-Activity Relationship; Superoxide Dismutase | 2007 |
Wilson's disease in two consecutive generations in a Bulgarian Roma family.
Topics: Adult; Aspartate Aminotransferases; Bulgaria; Child; Family Health; Female; Glutamine; Hepatolenticular Degeneration; Histidine; Humans; Male; Mutation | 2007 |
Post-translational modifications in the active site region of methyl-coenzyme M reductase from methanogenic and methanotrophic archaea.
Topics: Amino Acid Sequence; Archaea; Arginine; Binding Sites; Cysteine; Glutamine; Glycine; Histidine; Methane; Molecular Sequence Data; Oxidoreductases; Protein Processing, Post-Translational; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin | 2007 |
Enhancing the thermal stability of mitochondrial cytochrome b5 by introducing a structural motif characteristic of the less stable microsomal isoform.
Topics: Amino Acid Motifs; Apoenzymes; Arginine; Catalytic Domain; Cytochromes b5; Enzyme Stability; Glutamine; Histidine; Holoenzymes; Isoenzymes; Microsomes; Mitochondrial Membranes; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Denaturation; Serine; Spectrophotometry, Ultraviolet; Thermodynamics; Urea | 2007 |
Nemaline myopathy with exclusively intranuclear rods and a novel mutation in ACTA1 (Q139H).
Topics: Actins; DNA Mutational Analysis; Female; Glutamine; Histidine; Humans; Infant; Intranuclear Inclusion Bodies; Microscopy, Electron, Transmission; Models, Molecular; Muscle, Skeletal; Mutation; Myopathies, Nemaline | 2007 |
Binding of Ni2+ to a histidine- and glutamine-rich protein, Hpn-like.
Topics: Amino Acid Motifs; Amino Acid Sequence; Apoproteins; Bacterial Proteins; Blotting, Western; Cell Proliferation; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression; Glutamine; Helicobacter pylori; Histidine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nickel; Protein Binding; Protein Multimerization; Protein Structure, Quaternary; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2008 |
Ectopic expression of mouse Sry interferes with Wnt/beta-catenin signaling in mouse embryonal carcinoma cell lines.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; beta Catenin; Cell Line; Cell Line, Tumor; Glutamine; Histidine; Mice; Molecular Sequence Data; Sex Determination Processes; Signal Transduction; SOXB1 Transcription Factors; Wnt Proteins | 2008 |
Stability and ATP binding of the nucleotide-binding domain of the Wilson disease protein: effect of the common H1069Q mutation.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Substitution; Apoenzymes; Calorimetry, Differential Scanning; Cation Transport Proteins; Computational Biology; Computer Simulation; Copper-Transporting ATPases; Glutamine; Histidine; Holoenzymes; Humans; Kinetics; Models, Molecular; Mutant Proteins; Mutation; Nucleotides; Protein Folding; Protein Structure, Tertiary; Temperature; Thermodynamics; Tryptophan | 2008 |
The role of a conserved histidine residue in a pyruvate-specific Class II aldolase.
Topics: Alanine; Aldehyde-Lyases; Amino Acid Sequence; Amino Acid Substitution; Conserved Sequence; Escherichia coli Proteins; Evolution, Molecular; Glutamine; Histidine; Mutation; Protein Conformation; Pyruvic Acid | 2008 |
Importance of C-terminal flexible region of 4E-binding protein in binding with eukaryotic initiation factor 4E.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factors; Glutamine; Histidine; Humans; Molecular Sequence Data; Mutation; Protein Interaction Mapping; Protein Structure, Secondary | 2008 |
Association of MUTYH Gln324His and APEX1 Asp148Glu with colorectal cancer and smoking in a Japanese population.
Topics: Aged; Asian People; Aspartic Acid; Case-Control Studies; Colorectal Neoplasms; DNA Glycosylases; DNA-(Apurinic or Apyrimidinic Site) Lyase; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Glutamine; Histidine; Humans; Male; Middle Aged; Polymorphism, Genetic; Smoking | 2008 |
Methods for the purification of HQ-tagged proteins.
Topics: Animals; Cell Line; Cell-Free System; Chromatography, Affinity; Glutamine; Histidine; Mass Spectrometry; Recombinant Fusion Proteins | 2008 |
Structural and biophysical properties of the pathogenic SOD1 variant H46R/H48Q.
Topics: Amino Acid Substitution; Animals; Arginine; Cell Line; Copper; Crystallography, X-Ray; Enzyme Stability; Genetic Variation; Glutamine; Histidine; Humans; Mice; Mice, Transgenic; Molecular Chaperones; Mutation; Protein Processing, Post-Translational; Static Electricity; Superoxide Dismutase; Superoxide Dismutase-1 | 2009 |
Sonic hedgehog (SHH) mutation in patients within the spectrum of holoprosencephaly.
Topics: DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Glutamine; Hedgehog Proteins; Histidine; Holoprosencephaly; Humans; Magnetic Resonance Imaging; Male; Mutation | 2010 |
Polymorphisms of XRCC1 gene and risk of gastric cardiac adenocarcinoma.
Topics: Adenine; Adenocarcinoma; Adult; Aged; Arginine; Cardia; Case-Control Studies; Codon; Cytosine; DNA Repair; DNA-Binding Proteins; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamine; Haplotypes; Histidine; Humans; Linkage Disequilibrium; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Smoking; Stomach Neoplasms; Thymine; Tryptophan; X-ray Repair Cross Complementing Protein 1 | 2009 |
A correlation between the proton stretching vibration red shift and the hydrogen bond length in polycrystalline amino acids and peptides.
Topics: Amino Acids; Anions; Crystallization; Deuterium; Glutamine; Glycine; Histidine; Hydrogen Bonding; Imidazoles; Models, Chemical; Peptides; Protons; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Temperature | 2005 |
Kinetic and CD/MCD spectroscopic studies of the atypical, three-His-ligated, non-heme Fe2+ center in diketone dioxygenase: the role of hydrophilic outer shell residues in catalysis.
Topics: Acinetobacter; Catalysis; Circular Dichroism; Cysteine Dioxygenase; Dioxygenases; Enzyme Stability; Ferrous Compounds; Glutamic Acid; Glutamine; Hemeproteins; Histidine; Kinetics; Ligands; Mutagenesis, Site-Directed; Protein Binding; Water | 2010 |
Brain edema in acute liver failure: inhibition by L-histidine.
Topics: Ammonia; Animals; Brain; Brain Edema; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Heme Oxygenase-1; Histidine; Liver Failure, Acute; Male; Mitochondria; Permeability; Rats; Rats, Inbred F344 | 2010 |
Metabolomic analysis of serum by (1) H NMR spectroscopy in amyotrophic lateral sclerosis.
Topics: 3-Hydroxybutyric Acid; Acetates; Acetone; Adult; Amyotrophic Lateral Sclerosis; Female; Formates; Glutamic Acid; Glutamine; Histidine; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Sensitivity and Specificity | 2010 |
Structure and function of the apoA-IV T347S and Q360H common variants.
Topics: Amino Acid Substitution; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins A; Cell Line; Cholesterol; Endothelium, Vascular; Glutamine; Histidine; Homeostasis; Humans; Inflammation; Interleukin-6; Lipid Metabolism; Lipoproteins, HDL; Mice; Protein Structure, Secondary; Serine; Threonine; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2010 |
Studies on the catalytic mechanism of a glutamic peptidase.
Topics: Aspartic Acid; Carbon; Catalysis; Circular Dichroism; Fungi; Glutamine; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Peptide Hydrolases; Proline; Protein Conformation; Serine Endopeptidases; Tryptophan | 2010 |
Histidine, cystine, glutamine, and threonine collectively protect astrocytes from the toxicity of zinc.
Topics: Animals; Animals, Newborn; Antioxidants; Astrocytes; Cell Death; Cell Survival; Cells, Cultured; Cystine; Glutamine; Histidine; Mice; Mice, Inbred C57BL; Threonine; Zinc | 2010 |
Modification of the heme active site to increase the peroxidase activity of thermophilic cytochrome P450: a rational approach.
Topics: Amino Acid Substitution; Binding Sites; Catalysis; Chloride Peroxidase; Cytochrome b Group; Cytochrome P-450 Enzyme System; Enzyme Stability; Glutamine; Heme; Hemeproteins; Histidine; Horseradish Peroxidase; Hydrogen Bonding; Hydrogen-Ion Concentration; Oxidation-Reduction; Peroxidases; Structure-Activity Relationship; Thermus thermophilus | 2010 |
Insights into the mechanism of dihydropyrimidine dehydrogenase from site-directed mutagenesis targeting the active site loop and redox cofactor coordination.
Topics: Amino Acid Substitution; Animals; Arginine; Catalytic Domain; Cysteine; Dihydrouracil Dehydrogenase (NADP); Electron Spin Resonance Spectroscopy; Flavin-Adenine Dinucleotide; Flavins; Glutamine; Histidine; Hydrogen-Ion Concentration; Iron; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyrimidines; Serine; Spectrophotometry; Swine | 2010 |
Molecular basis of seed lipoxygenase null traits in soybean line OX948.
Topics: Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Breeding; Electrophoresis, Polyacrylamide Gel; Genes, Plant; Genetic Structures; Glutamine; Glycine max; Histidine; Lipoxygenase; Molecular Sequence Data; Mutation; Plant Proteins; Seeds; Sequence Analysis, DNA | 2011 |
P2RX7 polymorphisms Gln460Arg and His155Tyr are not associated with major depressive disorder or remission after SSRI or ECT.
Topics: Adult; Aged; Arginine; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Glutamine; Histidine; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptors, Purinergic P2X7; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Tyrosine | 2011 |
Metal-binding properties of an Hpn-like histidine-rich protein.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamine; Helicobacter pylori; Histidine; Humans; Magnetic Resonance Spectroscopy; Metals; Molecular Sequence Data; Nickel; Protein Binding; Proteins; Thermodynamics | 2011 |
Effect of the point mutation H148G on GFPmut2 unfolding kinetics by fluorescence spectroscopy.
Topics: Amino Acids; Glutamine; Green Fluorescent Proteins; Histidine; Kinetics; Point Mutation; Protein Conformation; Protein Denaturation; Protein Stability; Protein Unfolding; Spectrometry, Fluorescence | 2011 |
Lrrk2 p.Q1111H substitution and Parkinson's disease in Latin America.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Case-Control Studies; Female; Glutamine; Histidine; Humans; Indians, South American; Latin America; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Parkinson Disease; Protein Serine-Threonine Kinases; Young Adult | 2011 |
Biochemical properties and in vivo effects of the SOD1 zinc-binding site mutant (H80G).
Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Color Therapy; Disease Models, Animal; Endopeptidase K; Glutamine; Histidine; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Mice, Transgenic; Mutation; Oxidation-Reduction; Protein Binding; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Zinc | 2011 |
Dynamic water networks in cytochrome cbb3 oxidase.
Topics: Electron Transport Complex IV; Glutamine; Heme; Histidine; Hydrogen Bonding; Kinetics; Models, Molecular; Potassium Channels; Protons; Pseudomonas stutzeri; Water | 2012 |
Asparagine and glutamine differ in their propensities to form specific side chain-backbone hydrogen bonded motifs in proteins.
Topics: Amino Acid Motifs; Asparagine; Computational Biology; Glutamine; Histidine; Hydrogen Bonding; Protein Interaction Domains and Motifs; Protein Stability; Protein Structure, Secondary; Proteins | 2012 |
Ferroportin (SLC40A1) Q248H mutation is associated with lower circulating serum hepcidin levels in Rwandese HIV-positive women.
Topics: Adolescent; Adult; Amino Acid Substitution; Antimicrobial Cationic Peptides; Cation Transport Proteins; Cross-Sectional Studies; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Glutamine; Hepcidins; Histidine; HIV Infections; HIV Seropositivity; HIV-1; Humans; Middle Aged; Mutation, Missense; Osmolar Concentration; Rwanda; Young Adult | 2012 |
Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide.
Topics: Asparagine; Bacillus megaterium; Catalysis; Cytochrome P-450 Enzyme System; Diclofenac; Drug Discovery; Escherichia coli; Glutamine; Glycine; Histidine; Humans; Hydroxylation; Ibuprofen; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Tolbutamide | 2012 |
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response.
Topics: Adaptor Proteins, Signal Transducing; Amidohydrolases; Amino Acid Sequence; Animals; Aspartic Acid; B-Cell CLL-Lymphoma 10 Protein; Biocatalysis; Caspases; Catalytic Domain; Crystallography, X-Ray; Cysteine; Diglycerides; DNA Mutational Analysis; Dysentery, Bacillary; Glutamic Acid; Glutamine; HEK293 Cells; HeLa Cells; Histidine; Humans; Immunity, Innate; Inflammation; Mice; Models, Molecular; Molecular Sequence Data; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Neoplasm Proteins; NF-kappa B; Shigella flexneri; TNF Receptor-Associated Factor 6; Ubiquitin-Conjugating Enzymes; Virulence Factors | 2012 |
Homozygous point mutations in platelet glycoprotein ITGA2B gene as cause of Glanzmann thrombasthenia in 2 families.
Topics: Adolescent; Alleles; Amino Acid Substitution; Child; Child, Preschool; Chromosome Aberrations; Consanguinity; DNA Mutational Analysis; Exons; Female; Flow Cytometry; Genes, Recessive; Genetic Carrier Screening; Glutamine; Histidine; Homozygote; Humans; Integrin alpha2; Male; Mutation, Missense; Platelet Aggregation; Point Mutation; RNA Splicing; RNA, Messenger; Thrombasthenia | 2012 |
Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease.
Topics: alpha-Synuclein; Glutamine; Histidine; Humans; Male; Middle Aged; Mutation; Parkinson Disease; Pedigree | 2013 |
Combined effects of polymorphisms of DNA-repair protein genes and metabolic enzyme genes on the risk of cholangiocarcinoma.
Topics: Alanine; Arginine; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Cysteine; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; Genotype; Glutamine; Glutathione Transferase; Histidine; Humans; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors; Serine; Valine; X-ray Repair Cross Complementing Protein 1 | 2013 |
Role of the N-terminus of subunit III in proton uptake in cytochrome c oxidase of Rhodobacter sphaeroides.
Topics: Amino Acid Substitution; Catalytic Domain; Electron Transport Complex IV; Glutamine; Histidine; Hydrogen-Ion Concentration; Models, Molecular; Protein Subunits; Proton Pumps; Rhodobacter sphaeroides | 2014 |
Normal formiminoglutamic acid excreton in megaloblastic anaemia in pregnancy studies on histidine metabolism in pregnancy.
Topics: Anemia, Megaloblastic; Female; Formiminoglutamic Acid; Glutamine; Histidine; Humans; Pregnancy; Pregnancy Complications | 1963 |
Plasma amino acid profiles of breast cancer patients early in the trajectory of the disease differ from healthy comparison groups.
Topics: Adolescent; Adult; Amino Acids; Body Composition; Breast Neoplasms; Case-Control Studies; Energy Intake; Female; Glutamic Acid; Glutamine; Histidine; Humans; Leucine; Middle Aged; Threonine | 2014 |
Transport of L-glutamine, L-alanine, L-arginine and L-histidine by the neuron-specific Slc38a8 (SNAT8) in CNS.
Topics: Alanine; Amino Acid Transport Systems, Neutral; Animals; Arginine; Blotting, Western; Brain; Cells, Cultured; Electrophysiology; Female; Fluorescent Antibody Technique; Glutamine; Histidine; Immunoenzyme Techniques; In Situ Hybridization; Ion Transport; Male; Mice; Mice, Inbred C57BL; Neurons; Oocytes; Phylogeny; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Xenopus laevis | 2015 |
Relaxation-compensated difference spin diffusion NMR for detecting 13C-13C long-range correlations in proteins and polysaccharides.
Topics: Arabidopsis; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Cell Wall; Glucose; Glutamine; Histidine; N-Formylmethionine Leucyl-Phenylalanine; Nuclear Magnetic Resonance, Biomolecular; Plant Proteins; Polysaccharides | 2015 |
Dosimetry determines the initial OH radical concentration in fast photochemical oxidation of proteins (FPOP).
Topics: Deuterium; Free Radical Scavengers; Gas Chromatography-Mass Spectrometry; Glutamine; Histidine; Hydrogen Peroxide; Hydroxyl Radical; Indicator Dilution Techniques; Kinetics; Lasers; Methionine; Models, Molecular; Osmolar Concentration; Oxidants; Oxidation-Reduction; Phenylalanine; Photolysis; Proteins; Radiation Dosage | 2015 |
Association of XPD (Lys751Gln) and XRCC1 (Arg280His) gene polymorphisms in myelodysplastic syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Case-Control Studies; DNA-Binding Proteins; Female; Genetic Association Studies; Glutamine; Histidine; Humans; Lysine; Male; Middle Aged; Myelodysplastic Syndromes; Polymorphism, Single Nucleotide; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum Group D Protein; Young Adult | 2016 |
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor.
Topics: Arginine; Asparagine; Aspartate-Ammonia Ligase; Biological Transport; Cell Line, Tumor; Cell Proliferation; Culture Media; Gene Expression Regulation, Neoplastic; Glutamine; HeLa Cells; Histidine; Humans; Mechanistic Target of Rapamycin Complex 1; Metabolic Networks and Pathways; Multiprotein Complexes; Nucleotides; Serine; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
Crystal Structure of the Metallo-β-Lactamase GOB in the Periplasmic Dizinc Form Reveals an Unusual Metal Site.
Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Catalytic Domain; Cations, Divalent; Cephalosporins; Cloning, Molecular; Crystallography, X-Ray; Drug Resistance, Multiple, Bacterial; Escherichia coli; Flavobacteriaceae; Gene Expression; Glutamine; Histidine; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Penicillins; Periplasm; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Domains; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity; Zinc | 2016 |
Abnormal movement of tropomyosin and response of myosin heads and actin during the ATPase cycle caused by the Arg167His, Arg167Gly and Lys168Glu mutations in TPM1 gene.
Topics: Actins; Adenosine Triphosphatases; Animals; Arginine; Glutamine; Glycine; Histidine; Lysine; Male; Microscopy, Fluorescence; Mutation; Myosins; Nucleotides; Phalloidine; Rabbits; Recombinant Proteins; Temperature; Tropomyosin | 2016 |
Gating role of His 72 in TmPurL enzyme uncovered by structural analyses and molecular dynamics simulations.
Topics: Allosteric Regulation; Ammonia; Catalytic Domain; Glutamine; Histidine; Molecular Dynamics Simulation; Protein Conformation; Thermotoga maritima; Transaminases | 2016 |
Effect of Glu12-His89 Interaction on Dynamic Structures in HIV-1 p17 Matrix Protein Elucidated by NMR.
Topics: Amides; Codon; gag Gene Products, Human Immunodeficiency Virus; Glutamine; Histidine; HIV Antigens; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Mutation; Protein Binding; Protein Conformation; Protein Interaction Domains and Motifs; Protons; Structure-Activity Relationship; Thermodynamics | 2016 |
Translation-dependent bioassay for amino acid quantification using auxotrophic microbes as biocatalysts of protein synthesis.
Topics: beta-Galactosidase; Biological Assay; Calibration; Colorimetry; Genes, Reporter; Glutamic Acid; Glutamine; Green Fluorescent Proteins; Histidine; Lactococcus lactis; Luciferases; Protein Biosynthesis; Sensitivity and Specificity; Spectrometry, Fluorescence; Time Factors; Valine | 2017 |
The hydrogen peroxide hypersensitivity of OxyR2 in
Topics: Antioxidants; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Genetic Variation; Glutamine; Glycine; Histidine; Horseradish Peroxidase; Hydrogen Peroxide; Imidazoles; Kinetics; Lysine; Mutagenesis, Site-Directed; Mutation; Protein Multimerization; Repressor Proteins; RNA; Transcription Factors; Vibrio vulnificus | 2017 |
A Single Mutation is Sufficient to Modify the Metal Selectivity and Specificity of a Eukaryotic Manganese Superoxide Dismutase to Encompass Iron.
Topics: Catalytic Domain; DNA; Eukaryota; Gene Expression; Glutamine; Histidine; Iron; Metals; Molecular Dynamics Simulation; Mutation; Oxidation-Reduction; Protein Binding; Protein Conformation; Sensitivity and Specificity; Static Electricity; Superoxide Dismutase | 2018 |
Structural basis for methylphosphonate biosynthesis.
Topics: Alphaproteobacteria; Aquatic Organisms; Bacterial Proteins; Catalytic Domain; Glutamine; Histidine; Microbiota; Organophosphorus Compounds; Oxygenases; Phylogeny; Streptomyces | 2017 |
Serum metabolomics study in a group of Parkinson's disease patients from northern India.
Topics: Aged; Alanine; Female; Glutamine; Histidine; Humans; India; Isoleucine; Male; Metabolomics; Middle Aged; Multiple System Atrophy; Parkinson Disease; Proton Magnetic Resonance Spectroscopy; Supranuclear Palsy, Progressive; Valine | 2018 |
The CCCH-type zinc finger transcription factor Zc3h8 represses NF-κB-mediated inflammation in digestive organs in zebrafish.
Topics: Amino Acid Sequence; Animals; Apoptosis; Cell Proliferation; Cytokines; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Glutamine; Hepatocytes; Histidine; Inflammation; Intestines; Liver; Macrophages; Mutation; NF-kappa B; Pancreas, Exocrine; Phagocytosis; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Transcription Factors; Zebrafish; Zebrafish Proteins; Zinc Fingers | 2018 |
Role of a conserved glutamine in the function of voltage-gated Ca
Topics: Amino Acid Sequence; Calcium Channels, L-Type; Calcium Signaling; Conserved Sequence; Exome Sequencing; Glutamine; Glycine; Hearing Loss; Histidine; Humans; Intellectual Disability; Ion Channel Gating; Mutation; Sequence Homology, Amino Acid; Synaptic Transmission | 2018 |
Analysis of Single-Nucleotide Polymorphisms in Human Voltage-Gated Ion Channels.
Topics: Amino Acid Sequence; Arginine; Calcium Channels; Channelopathies; Cysteine; Databases, Protein; Gene Expression; Glutamine; Histidine; Humans; Ion Channel Gating; Models, Molecular; Polymorphism, Single Nucleotide; Potassium Channels, Voltage-Gated; Protein Conformation; Protein Domains; Proteomics; Voltage-Gated Sodium Channels | 2019 |
Search for Early Pancreatic Cancer Blood Biomarkers in Five European Prospective Population Biobanks Using Metabolomics.
Topics: Aged; Biological Specimen Banks; Biomarkers, Tumor; Case-Control Studies; Early Diagnosis; Europe; Female; Glutamine; Histidine; Humans; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Pancreatic Neoplasms | 2019 |
Structural basis of second-generation HIV integrase inhibitor action and viral resistance.
Topics: Amides; Amino Acid Substitution; Catalytic Domain; Cryoelectron Microscopy; Drug Resistance, Viral; Glutamine; Glycine; Heterocyclic Compounds, 3-Ring; Heterocyclic Compounds, 4 or More Rings; Histidine; HIV Integrase; HIV Integrase Inhibitors; Humans; Magnesium; Mutation; Oxazines; Piperazines; Pyridones; Serine; Single Molecule Imaging | 2020 |
A novel heterozygous mutation in the insulin receptor gene presenting with type A severe insulin resistance syndrome.
Topics: Acanthosis Nigricans; Amino Acid Substitution; Antigens, CD; Child; Delayed Diagnosis; Diabetes Mellitus, Type 1; Diagnostic Errors; Donohue Syndrome; Female; Glutamine; Heterozygote; Histidine; Humans; Insulin Resistance; Jamaica; Mutation, Missense; Polymorphism, Single Nucleotide; Receptor, Insulin | 2020 |
Spontaneous conversions of glutamine, histidine and arginine into α-hydroxycarboxylates with NH
Topics: Arginine; Carboxylic Acids; Glutamine; Histidine; Hydrogen Bonding; Stereoisomerism; Vanadates; Vanadium Compounds | 2020 |
Biallelic variants in SLC38A3 encoding a glutamine transporter cause epileptic encephalopathy.
Topics: Epilepsy, Generalized; Glutamine; Histidine; Humans; Metabolome; Nitrogen; Sodium-Calcium Exchanger | 2022 |
A Comparative Study on Nickel Binding to Hpn-like Polypeptides from Two
Topics: Amino Acid Sequence; Bacterial Proteins; Calorimetry; Glutamine; Helicobacter pylori; Histidine; Nickel; Peptides; Potentiometry; Protein Domains | 2021 |
Microbiota and Metabolite Profiling as Markers of Mood Disorders: A Cross-Sectional Study in Obese Patients.
Topics: Amino Acids; Biomarkers; Cross-Sectional Studies; Female; Gastrointestinal Microbiome; Glutamine; Histidine; Humans; Male; Mood Disorders; Obesity | 2021 |
Side effects of amino acid supplements.
Topics: Aged; Amino Acids; Arginine; Child; Dietary Supplements; Female; Glutamine; Histidine; Humans; Muscle, Skeletal; Pregnancy | 2022 |
Isolation and characterization of novel antihypertensive bioactive peptides from brassica napus and angiotensin-converting enzyme (ace) inhibition potential.
Topics: Alanine; Angiotensins; Antihypertensive Agents; Arginine; Brassica napus; Cysteine; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptides; Peptidyl-Dipeptidase A; Phenylalanine; Proline; Tandem Mass Spectrometry; Threonine; Tyrosine; Valine | 2022 |
Enterovirus 3C Protease Cleaves TRIM7 To Dampen Its Antiviral Activity.
Topics: 3C Viral Proteases; Animals; Enterovirus; Enterovirus Infections; Glutamine; Histidine; Host-Pathogen Interactions; Phascolarctidae; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2022 |
Impact of Inhibition of Glutamine and Alanine Transport on Cerebellar Glial and Neuronal Metabolism.
Topics: Acetates; Alanine; Ammonia; Animals; Carbon; Cerebellum; Glucose; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine | 2022 |
Changes in aging-induced kidney dysfunction in mice based on a metabolomics analysis.
Topics: Aging; Animals; Biomarkers; Citrates; Glutamic Acid; Glutamine; Glyoxylates; Histidine; Kidney; Male; Mice; Nucleotides; Purines; Pyruvates; Renal Insufficiency; Tricarboxylic Acids | 2022 |
Intestinal metabolomics of juvenile lenok (Brachymystax lenok) in response to heat stress.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Acetylcarnitine; Animals; Aspartic Acid; Erucic Acids; Glucose; Glutamine; Heat-Shock Response; Histidine; Intestines; Lactates; Leucine; Methionine; Oxylipins; Palmitoylcarnitine; Phenylalanine; Phosphatidylcholines; Phosphorylcholine; Proline; Salmonidae; Tandem Mass Spectrometry; Tryptophan; Tyrosine | 2022 |
Pan-cancer analysis of pre-diagnostic blood metabolite concentrations in the European Prospective Investigation into Cancer and Nutrition.
Topics: Carcinoma, Hepatocellular; Case-Control Studies; Glutamine; Histidine; Humans; Liver Neoplasms; Lysophosphatidylcholines; Male; Phosphatidylcholines; Proline; Prospective Studies; Risk Factors; Sphingomyelins | 2022 |
Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts.
Topics: Amino Acids; Biological Specimen Banks; Colorectal Neoplasms; Glutamine; Histidine; Humans; Prospective Studies; United Kingdom | 2023 |
Lipid Peroxidation Products Influence Calpain-1 Functionality In Vitro by Covalent Binding.
Topics: Aldehydes; Asparagine; Calpain; Chromatography, Liquid; Glutamine; Hexobarbital; Histidine; Lipid Peroxidation; Lysine; Tandem Mass Spectrometry | 2023 |
The Association between Macrosomia and Amino Acids' Levels in Maternal and Cord Sera: A Case-Control Study.
Topics: Alanine; Amino Acids; Arginine; Case-Control Studies; Chromatography, Liquid; Female; Fetal Macrosomia; Glutamic Acid; Glutamine; Histidine; Humans; Infant, Newborn; Leucine; Methionine; Tandem Mass Spectrometry; Threonine; Tryptophan; Valine | 2023 |