histidine has been researched along with cysteine in 1226 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 348 (28.38) | 18.7374 |
| 1990's | 254 (20.72) | 18.2507 |
| 2000's | 400 (32.63) | 29.6817 |
| 2010's | 184 (15.01) | 24.3611 |
| 2020's | 40 (3.26) | 2.80 |
| Authors | Studies |
|---|---|
| Parish, HA; Spatola, AF; Yankeelov, JA | 1 |
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Dean, KE; Klein, G; Renaudet, O; Reymond, JL | 1 |
| Cieszkowski, M; Konturek, SJ; Obtulowicz, W; Tasler, J | 1 |
| Gaudemer, Y; Latruffe, N | 1 |
| Brown, JP; Hartman, FC | 1 |
| Keil, B; Keil-Dlouha, V; Lecroisey, A; Perrin, D; Woods, DR | 1 |
| Hiwatashi, A; Ichikawa, Y; Maruya, N; Yamano, T | 1 |
| Petz, D; Schneider, F | 1 |
| Conti, SF; LaMarre, AG; Straley, SC | 1 |
| Brochlehurst, K; Shipton, M | 1 |
| Hiwatashi, A; Ichikawa, Y | 1 |
| Brocklehurst, K; Malthouse, JP; Shipton, M | 1 |
| Kowalski, M; Małek, W | 1 |
| Rosin, MP; Stich, HF | 1 |
| Mason, J; McGivern, J | 1 |
| Carrette, J; Chelis, C; Leger, DS; Tenu, JP | 1 |
| Beaton, JM; Bradley, RJ; Smythies, JR | 1 |
| Noda, L; Schulz, GE; Von Zabern, I | 1 |
| Leskovac, V; Pavkov-Pericin, D | 1 |
| Chin, CC; Daley, G; Warren, JC | 1 |
| Dickenson, CJ; Dickinson, FM | 1 |
| Schweri, MM; Wacker, WB; Yankeelov, JA | 1 |
| Johnsen, RH; Rezk, AM | 1 |
| Brocklehurst, K; Kierstan, MP; Malthouse, JP; Shipton, M; Stuchbury, T | 1 |
| Chen, SN; Hoffman, MZ | 1 |
| Gregory, EM | 1 |
| Bandurski, RS; Felker, P | 1 |
| Umbarger, HE | 1 |
| Borst, P; Bos, JL; Osinga, KA; Van der Horst, G | 1 |
| Beaune, P; Cresteil, T; Lange, M; Leroux, JP; Mansuy, D | 1 |
| Aldridge, WN; Bridges, JW; Elliott, BM | 1 |
| Joris, L; Sun, SC; Tsolas, O | 1 |
| Hill, HA; Smith, BE | 1 |
| Haygood, CC; King, RW; Kraikitpanitch, S; Lindeman, RD; Yunice, AA | 1 |
| Edmondson, DE; Singer, TP | 4 |
| Fournier, MJ; Kitchingman, GR; Webb, E | 1 |
| Felker, P | 1 |
| Hall, IH; Lee, KH; Mar, EC; Starnes, CO; Waddell, TG | 1 |
| Heller, MJ; Klotz, IM; Walder, JA | 1 |
| Cousineau, J; Meighen, E | 1 |
| Halász, P; Polgár, L | 2 |
| Ahlers, J; Günther, T | 1 |
| Bazile, J; Cordier, JP; Frourin, A; Jondeau, D; Thenot, M | 1 |
| Yamamoto, O | 1 |
| Sun, SC; Tsolas, O | 1 |
| Muller, S; Olitzki, AL | 1 |
| De Bersaques, J | 1 |
| Casey, R; Lang, A | 1 |
| Chin, CC; Wold, F | 1 |
| El-Bassoussy, M; El-Hawary, MF; El-Shobaki, FA; Kholeif, T; Sakr, R | 1 |
| Burroughs, W; Mertens, DR; Nelson, DK | 1 |
| Bayer, E; Hemmasi, B | 1 |
| Aldrich, JE; Hunt, JW; Lam, KY; Shragge, PC | 1 |
| Hewitt, JA; Kilmartin, JV; Wootton, JF | 1 |
| Kulbe, KD | 2 |
| Guadalix, FJ; Ruiz, MC | 1 |
| Elliott, SD; Kortt, AA; Liu, TY; Tai, JY | 1 |
| Mogil'naia, GM; Shubich, MG | 1 |
| Lloyd, RE; Yu, SF | 1 |
| Ikehara, M; Ishikawa, M; Kanaya, S; Katayanagi, K; Matsushima, M; Matsuzaki, T; Miyagawa, M; Morikawa, K; Nakamura, H | 1 |
| Atta-Asafo-Adjei, E; Daldal, F; Davidson, E; Ohnishi, T | 1 |
| Choe, HW; Grunert, HP; Hahn, U; Heinemann, U; Koellner, G; Saenger, W; Zouni, A | 1 |
| Andersson, L; Porath, J; Sulkowski, E | 1 |
| Croteau, R; Gershenzon, J; Miyazaki, J; Rajaonarivony, JI | 1 |
| De Groot, RJ; Levinson, R; Strauss, EG; Strauss, JH | 1 |
| Dalton, H; Smith, DD | 1 |
| Andersson, L; Hansen, P; Lindeberg, G | 1 |
| Asahara, H; Hasegawa, T; Himeno, H; Shimizu, M; Tamura, K | 1 |
| Lee, MS; Mortishire-Smith, RJ; Wright, PE | 1 |
| Naggert, J; Randhawa, ZI; Smith, S; Witkowska, HE; Witkowski, A | 1 |
| Engler, JA; Joung, I | 1 |
| Abramson, JJ; Favero, TG; Pessah, IN; Stuart, J | 1 |
| Deyashiki, Y; Hara, A; Nakayama, T; Sawada, H; Shinoda, M; Tanabe, H | 1 |
| Aoki, D; Dubois, C; Fukuda, MN; Lee, N; Yamaguchi, N | 1 |
| Chueh, LL; Hayakawa, H; Nakamura, T; Nakatsu, Y; Sakumi, K; Sekiguchi, M | 1 |
| Cheon, HG; Hanna, PE | 1 |
| Belsham, DD; Bordet, S; Greenberg, C; Kaufman, M; Mhatre, A; Pereira, F; Pinsky, L; Prior, L; Trifiro, MA; Wrogeman, K | 1 |
| Lu, AY; Newton, DJ; Pickett, CB; Wang, RW | 1 |
| Ahn, HS; Foster, C; Foster, M; Sybertz, E; Wells, JN | 1 |
| Harada, I; Takeuchi, H; Yoshida, H | 1 |
| Edlund, T; Karlsson, O; Norberg, T; Ohlsson, H; Thor, S | 1 |
| Hill, KA; Miller, WT; Schimmel, P | 1 |
| Bolinger, L; Lee, MS; Mortishire-Smith, RJ; Wright, PE | 1 |
| Davis, JP; Van Etten, RL; Zhang, ZY | 1 |
| Inoue, H; Kong, KH; Takahashi, K | 1 |
| Caine, JM; McLeish, MJ | 1 |
| Gachot, B; Morat, L; Poujeol, P; Tauc, M | 1 |
| Bennich, H; Engström, A; Lindeberg, G | 1 |
| Antoine, M; Benn, A; Beug, H; Niessing, J | 1 |
| Dulik, DM; Hayden, PJ; McCann, DJ; Stevens, JL; Ward, AJ; Yang, Y | 1 |
| Fahmy, AS; Ghazy, AH; Kamel, MY; Mohamed, MA | 1 |
| Adachi, S; Ishimori, K; Morishima, I; Nagano, S; Watanabe, Y | 1 |
| Etkin, LD; Reddy, BA | 1 |
| Canters, GW; Koningsberger, DC; Lommen, A; Pandya, KI | 1 |
| Pereira, B; Sivakami, S | 1 |
| Atkinson, T; Gore, MG; Scawen, MD; Spencer, P | 1 |
| Kanofsky, JR; Sima, P | 1 |
| Damay, P; Dupraz, P; Meric, C; Oertle, S; Spahr, PF | 1 |
| Aulak, KS; Harrison, RS | 1 |
| Clarke, ND; Regan, L | 1 |
| Brigle, KE; Dean, DR; Laird, NF; Newton, WE; Scott, DJ; Setterquist, RA | 1 |
| Kilberg, MS; Mailliard, ME | 1 |
| Bray, MR; Clarke, AJ | 1 |
| Bishop, LJ; Cohen, FS; Cramer, WA; Davidson, VL | 1 |
| Bhattacharyya, D; Foote, RS; Mitra, S; Mural, RJ; Tano, K | 1 |
| Ahmed, SA; Kawasaki, H; Miles, EW; Morita, H; Nagata, S | 1 |
| Zlotkin, SH | 1 |
| Case, DA; Gippert, GP; Lee, MS; Soman, KV; Wright, PE | 1 |
| Raffaniello, RD; Wapnir, RA | 1 |
| Liao, YD; Shang, Z; Wu, CW; Wu, FY | 1 |
| Mei, B; Zalkin, H | 1 |
| Jentoft, JE; Katz, RA | 1 |
| Andrews, JC; Bavister, BD | 1 |
| Feiters, MC; Jeffery, J | 1 |
| Fee, JA; Münck, E; Nitsche, CI; Rusnak, F; Zimmermann, BH | 1 |
| Fu, XD; Jentoft, JE; Johnson, M; Leis, J; Smith, LM | 1 |
| Kishi, F; Nakazawa, A; Sanders, CR; Tian, GC; Tsai, MD | 1 |
| Fisher, SE; Karl, PI; Tkaczevski, H | 1 |
| Behere, DV; Goff, HM; Gonzalez-Vergara, E | 1 |
| Kim, HS; Legoy, MD; Minard, P; Thomas, D | 1 |
| Cullis, PM; Kleanthous, C; Lewendon, A; Murray, IA; Shaw, WV | 1 |
| Igarashi, K; Ito, K | 1 |
| Gilles, P; Keudell, KC; Robertson, NL | 1 |
| Dolphin, PJ; Jauhiainen, M; Ridgway, ND | 1 |
| Pas, HH; Robillard, GT | 1 |
| Di Marzo, V; Erdjument, H; Lane, DA; Morris, HR; Panico, M | 1 |
| Rusconi, S; Schaffner, W; Severne, Y; Wieland, S | 1 |
| Baker, EN | 1 |
| Kustrzeba-Wójcicka, I; Pietkiewicz, J; Wolna, E; Wolny, M | 1 |
| Dugan, RE; Katiyar, SS | 1 |
| Gasser, KW; Kirschner, LB | 1 |
| Ballou, DP; Lewis, SD; Olson, ST; Roberts, DD; Shafer, JA | 1 |
| Stiel, L; Wapnir, RA | 1 |
| Berglin, EH; Carlsson, J | 1 |
| Dupressoir, T; Lanneau, M; Loir, M; Sautière, P | 1 |
| Colman, RF; Tomich, JM | 1 |
| Lin, FP; Sanny, CG; Weiner, H | 1 |
| Bishop, LJ; Bjes, ES; Cramer, WA; Davidson, VL | 1 |
| Karlsson, JO; Sjöstrand, J | 1 |
| Prento, P | 1 |
| Everett, MM; Miller, WA | 3 |
| Habeeb, AJ; Hiramoto, R | 1 |
| Marinetti, GV; Pettit, D | 1 |
| Ellis, HK; Watkins, WB | 1 |
| Delgado, NM; Huacuja, L; Rosado, A; Sosa, A | 1 |
| Dalen, AB | 1 |
| Maino, VC; Young, FE | 1 |
| Klee, CB | 2 |
| Hegyi, G; Horányi, M; Mühlrad, A | 1 |
| Oe, M; Seon, BK; Titani, K; Tonomura, Y | 1 |
| Braun, V; Rehn, K; Wolff, H | 1 |
| Bertolini, R; Gabler, W; Pabst, R | 1 |
| Olitzki, AL | 1 |
| Andrews, MJ; Turner, JM | 1 |
| Muench, KH; Safille, PA | 1 |
| Commoner, B; Tiezzi, E; Woolum, JC | 1 |
| Baumann, P; Wright, BE | 1 |
| Batke, J; Keleti, T | 1 |
| Horecker, BL; Nakashima, K; Pontremoli, S; Traniello, S | 1 |
| Mansour, TE; Setlow, B | 1 |
| Berry, SA; Campbell, JN | 1 |
| Calabrese, L; Rotilio, G | 1 |
| Gregory, EM; Harrison, JH; Rohrbach, MS | 1 |
| Karadźić, V; Micić, D; Rakić, L | 1 |
| Elek, G; Keleti, T | 1 |
| Fenselau, A; Moore, J | 1 |
| Francis, SH; Meriwether, BP; Park, JH | 1 |
| Danson, MJ; Weitzman, PD | 2 |
| Ward, S | 1 |
| Campbell, LL; Trousil, EB | 1 |
| Loock, B; Momenteau, M | 1 |
| Cozzani, I; Gennari, G; Jori, G; Santoni, C; Tamburro, AM | 1 |
| Huestis, WH; Raftery, MA | 1 |
| Amons, R; Groene, A; Möller, W; Terhorst, C | 1 |
| Robinson, JW | 1 |
| Horecker, BL; Lai, CY | 1 |
| Grouselle, M; Pudles, J; Thiam, AA | 1 |
| Bhattacharya, RK | 1 |
| Horecker, BL; Tsolas, O | 1 |
| Henkin, RI | 1 |
| Atherly, AG | 1 |
| Benson, CE; Gots, JS | 1 |
| Kenney, WC; Singer, TP | 1 |
| Host, WR; Rush, BF; Serlin, O | 1 |
| Lehmann, H; Romero Herrera, AE | 1 |
| Gladner, JA; Klee, CB | 1 |
| Bradbury, JH; Ley, KF | 1 |
| Ericsson, LH; Hermodson, MA; Neurath, H; Titani, K; Walsh, KA | 1 |
| Van Campen, D | 1 |
| Fasold, H; Meyer, C; Steinkopff, G | 1 |
| Good, RA; Jose, DG | 1 |
| Polgár, L | 1 |
| Morino, Y; Okamoto, M | 1 |
| Eyem, J; Sjöquist, J | 1 |
| Akimoto, H; Ho, R; Price, CC | 1 |
| Gebhart, E | 1 |
| Allen, GA; Burgess, RC; Eggert, FM | 1 |
| Balasubramanian, M; Myers, RF | 1 |
| Holton, JB; Tyfield, LA | 1 |
| Liao, TH; Moore, S; Salnikow, J; Stein, WH | 1 |
| Plapp, BV | 1 |
| Allen, G; Lowe, G | 1 |
| Van Heyningen, R | 1 |
| Niall, HD | 1 |
| Olomucki, A; Thomé-Beau, F | 1 |
| Harrison, PM; Hoy, TG; Macara, IG | 1 |
| Kirschenbaum, DM | 1 |
| Bahadur, K; Singh, YP; Verma, ML | 1 |
| Read, CP; Ruff, MD | 1 |
| Kanamarlapudi, NR; Sweet, F; Warren, JC | 1 |
| Malek, W | 1 |
| Chow, RB; Kassel, B | 1 |
| Serény, B | 1 |
| Horecker, BL; Morse, DE | 1 |
| Singer, SJ | 1 |
| Crawford, IP; Hatanaka, M; Ito, J | 1 |
| Anker, HS; Fenster, ED | 1 |
| Borek, E; Hay, J; Pillinger, DJ | 1 |
| Fackre, D; Jurasek, L; Smillie, LB | 1 |
| Biserte, G | 1 |
| Stark, GR | 1 |
| Jörnvall, H | 1 |
| Kishida, Y; Sakakibara, S | 1 |
| Turbakiewicz, L | 1 |
| DeLange, RJ; Smith, EL | 1 |
| Anderson, B; Kundig, W; Roseman, S; Weigel, N | 1 |
| Kotyk, A; Ponec, M; Ríhová, L | 1 |
| Fontana, A; Scoffone, E | 1 |
| Edman, P | 1 |
| Becker, WM; Hoekstra, WG | 1 |
| Novello, F; Stirpe, F | 1 |
| Pierpoint, WS | 1 |
| Beaman, TC; Gerhardt, P; Matz, LL | 1 |
| Allen, CF; Cohen, LW; Kniprath, WG | 1 |
| Jolley, CJ; Yankeelov, JA | 2 |
| Lacombe, G; Thiem, NV; Thoai, NV | 1 |
| Sweet, F; Warren, JC | 1 |
| Cornell, NW; Crivaro, KE | 1 |
| Nelson, N; Racker, E | 1 |
| Giroux, EL; Henkin, RI | 1 |
| Mackenzie, RE; Rabinowitz, JC; Straus, LD | 1 |
| Jacobsen, C | 1 |
| Ciegler, A; Leistner, L; Mintzlaff, HJ; Weisleder, D | 1 |
| Adams, GE; Aldrich, JE; Bisby, RH; Cundall, RB; Redpath, JL; Willson, RL | 1 |
| Holt, LA; Milligan, B | 1 |
| Diopoh, J; Olomucki, M | 1 |
| Ruckhäberle, KE; Viehweg, B; Wolff, C | 3 |
| Brocklehurst, K; Little, G | 2 |
| Davies, JV; Ebert, M; Musch, K; Siebert, G | 1 |
| Shepherd, SL; Wagner, FW | 1 |
| Arndt, DJ; Konigsberg, W; Maita, T; Simon, SR | 1 |
| Shall, S; Waheed, A | 1 |
| Hornig, D; Weber, F; Wiss, O | 1 |
| Markelova, SI; Zharikova, GG | 3 |
| Fishman, WH; Sie, HG | 1 |
| Kassab, R; Pradel, LA; Roustan, C; Van Thoai, N | 1 |
| Furka, A | 1 |
| Cooper, MR; DeChatelet, LR; McCall, CE | 1 |
| Gowenlock, AH; Redford-Ellis, M | 1 |
| Kabat, EA | 1 |
| Gibbons, RJ; Loesche, WJ | 1 |
| Bender, ML; Polgár, L | 1 |
| Adamson, J; Hayashi, A; Stamatoyannopoulos, G; Yoshida, A | 1 |
| Gennari, G; Jori, G; Scoffone, E; Toniolo, C | 1 |
| Holland, JF; Onuma, T; Waligunda, J | 1 |
| Butt, WR | 1 |
| Jones, DS; Khorana, HG; Nishimura, S | 1 |
| Khorana, HG; Morgan, AR; Wells, RD | 1 |
| Fedorchenko, EIa; Gulyi, MF; Orlov, LP; Petrun', LM; Pisarevich, EV | 1 |
| Galiazzo, G; Jori, G; Scoffone, E | 1 |
| Martinez-Carrion, M; Peterson, DL | 1 |
| Elzinga, M | 1 |
| Husain, SS; Lowe, G | 6 |
| Cook, ES; Nutini, LG; Tanaka, K; Tsuchiya, Y | 1 |
| Bolinder, AE | 1 |
| Chin, CC; Warren, JC | 1 |
| Lingens, F; Sprössler, B | 1 |
| Bucovaz, ET; Dais, CF; James, HL; Morrison, JC; Wood, JL | 1 |
| Neuhoff, V; Weise, M | 1 |
| A'zary, EP; Bigelow, CC | 1 |
| Baranova, IP; Egorov, NS | 1 |
| Hodges, RS; Smillie, LB | 1 |
| Basappa, SC; Rehácek, Z | 1 |
| Hammerstedt, RH; Robertson, DC; Wood, WA | 1 |
| Desnuelle, P; Dufour, C; Sémériva, M | 1 |
| Huc, C; Olomucki, A | 1 |
| Craigie, JS; Laycock, MV | 1 |
| Kloss, G; Schwarz, E | 1 |
| Kickuth, R; Scheffer, F; Schlimme, E | 1 |
| Saito, N | 1 |
| Curtius, HC; Tancredi, F | 1 |
| Ansorge, S; Bohley, P | 1 |
| Hopsu-Havu, VK; Mäkinen, KK | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Genghof, DS; Van Damme, O | 1 |
| Brown, JH; Mackey, HK | 1 |
| Akoyunoglou, G; Argyroudi-Akoyunoglou, J | 1 |
| Manahan, J; Mandl, I | 1 |
| Steenbergen, ST; Weinberg, ED | 1 |
| Cornell, NW; Villee, CA | 1 |
| Kolomiĭchenko, MA | 1 |
| Schneider, G | 1 |
| Pavlenko, LM; Sukhomlinov, BF | 1 |
| Carsten, ME; Gaspar-Godfroid, A; Gerday, C; Gosselin-Rey, C | 1 |
| Fondy, TP; Ross, CR; Sollohub, SJ | 1 |
| Anwar, RA; Narayanan, AS | 1 |
| Connell, GE; Szewczuk, A | 1 |
| Anglin, JH; Bever, AT; Everett, MA; Jones, DH | 1 |
| Handler, P; Hashimoto, T | 1 |
| Hoekstra, WG; Nielsen, FH; Sunde, ML | 1 |
| Munier, RL; Sarrazin, G | 1 |
| Stadler, DR | 1 |
| Menkès, G | 1 |
| Harper, E; Scharrer, B; Seifter, S | 1 |
| Agnihotri, VP; Vaartaja, O | 1 |
| Shaltiel, S | 1 |
| Lerch, K | 1 |
| Luzio, JP; Newby, AC; Worku, Y | 1 |
| Glatt, H; Oesch, F; Protić-SabljiC, M | 1 |
| Kenyon, GL; Reed, GH | 1 |
| Loehr, TM; Maret, W; Sanders-Loehr, J; Zeppezauer, M | 1 |
| Barnea, A; Cho, G | 1 |
| Gilles, AM; Keil, B | 1 |
| Ikemoto, N | 1 |
| Appaji Rao, N; Manohar, R | 1 |
| Layrisse, M; Leets, I; Martínez-Torres, C; Ramírez, J; Taylor, P | 1 |
| Barker, DG; Winter, G | 1 |
| Gracy, RW; Lu, HS | 1 |
| Kilberg, MS | 1 |
| Greger, JL; Snedeker, SM | 1 |
| Fan, CC; Huennekens, FM; Vitols, KS | 1 |
| Mildvan, AS; Smith, GM | 1 |
| Johnson, B; Vander, AJ | 1 |
| Lau, SS; Zannoni, VG | 1 |
| Bloxham, DP | 1 |
| Edwards, BF; Sykes, BD | 1 |
| Sharma, RP; Verma, MP | 1 |
| Johnson, FA; Lewis, SD; Shafer, JA | 1 |
| Belsham, GJ; Roberts, PJ | 1 |
| Gether, U; Kobilka, BK; Lin, S | 1 |
| Orlinsky, KJ; Sandmeyer, SB | 1 |
| Masters, BS; McMillan, K | 1 |
| Ferrer, JC; Hildebrand, DP; Mauk, AG; Smith, M; Tang, HL | 1 |
| Banci, L; Bertini, I; Borsari, M; Hallewell, RA; Viezzoli, MS | 1 |
| Brennan, TV; Clarke, S | 1 |
| Duckett, DR; Giraud-Panis, MJ; Lilley, DM | 1 |
| Coulter, KL; Périer, F; Radeke, CM; Vandenberg, CA | 1 |
| Gonnelli, M; Strambini, GB | 1 |
| Gerchman, Y; Olami, Y; Padan, E; Rimon, A; Schuldiner, S | 1 |
| Kim, YT; Muramatsu, T; Takahashi, K | 1 |
| Clarke, ND; Gardner, KH; Klemba, M; Marino, S; Regan, L | 1 |
| Bird, M; Britten, C; Hood, C | 1 |
| Arakawa, T; Fox, GM; Holst, PL; Horan, TP; Narhi, LO; Prestrelski, SJ; Rees, DC; Schiffer, SG; Tsai, LB | 1 |
| Fukuda, MN; Yamaguchi, N | 1 |
| Elling, L | 1 |
| Freedman, RB; Gane, PJ; Warwicker, J | 1 |
| Offer, G; Sessions, R | 1 |
| Pisoni, RL; Velilla, VQ | 1 |
| Erdmann, R; Kunau, WH; Mathieu, M; Pauptit, RA; Wierenga, RK; Zeelen, JP | 1 |
| Dodson, EJ; Dodson, G; Duggleby, HJ; Hill, CP; Moody, PC; Tolley, SP | 1 |
| Baumeister, W; Lupas, A; Seemüller, E; Zühl, F; Zwickl, P | 1 |
| Block, MA; Douce, R; Joyard, J; Maréchal, E; Miège, C | 1 |
| Beckman, JS; Crow, JP; McCord, JM | 1 |
| Darlix, JL; Déméné, H; Dong, CZ; Fournié-Zaluski, MC; Jullian, N; Mely, Y; Morellet, N; Ottmann, M; Rouyez, MC; Saragosti, S | 1 |
| Charlesworth, P; Dubbelman, TM; Lagerberg, JW; Truscott, TG; VanSteveninck, J | 1 |
| Altschuh, D; Tessier, DC; Vernet, T | 1 |
| Ohnishi, T; Sled, VD; Yagi, T; Yano, T | 1 |
| Brocklehurst, K; Patel, M; Pinitglang, S; Thomas, EW | 1 |
| Barroso, LA; Lyerly, DM; Moncrief, JS; Wilkins, TD | 1 |
| Aiach, M; Aillaud, MF; Alhenc-Gelas, M; Duchemin, J; Emmerich, J; Gandrille, S; Gaussem, P | 1 |
| Peseckis, SM; Resh, MD | 1 |
| Laskar, O; Schuldiner, S; Shirvan, A; Steiner-Mordoch, S | 1 |
| Bayley, H; Braha, O; Krishnasastry, M; Walker, B | 1 |
| Brocklehurst, K; Kowlessur, D; Mellor, GW; Thomas, EW; Thomas, MP; Topham, CM; Whitford, D | 1 |
| Bransom, KL; Dreher, TW | 1 |
| Bianchi, F; Hublau, P; Rousseaux, J; Rousseaux-Prevost, R | 1 |
| Bernstein, BE; Hoffman, RC; Klevit, RE | 1 |
| Coleman, CS; Pegg, AE; Stanley, BA; Viswanath, R | 1 |
| Kinuta, M; Shimizu, H; Ubuka, T; Yao, WB; Zhao, YQ | 1 |
| Margalit, H; Rosenfeld, R | 1 |
| Accornero, P; Carrera, G; Curti, B; Vanoni, MA | 1 |
| Hayward, GS; Kaushal, S; Kinchington, PR; Mosca, JD; Perera, LP; Straus, SE | 1 |
| Birnbaum, MJ; Clem, RJ; Miller, LK | 1 |
| Bernstein, BE; Herriott, JR; Hoffman, RC; Horvath, S; Klevit, RE | 1 |
| Anderson, PM; Cho, YG; Holcomb, TA; Korte, JJ; Son, CM; Sung, YC | 1 |
| Chueh, LL; Hayakawa, H; Ihara, K; Kawate, H; Sekiguchi, M | 1 |
| Beydon, D; Fabry, JP; Langonne, I; Payan, JP; Sabate, JP; Saillenfait, AM | 1 |
| Borden, KL; Etkin, LD; Freemont, PS; Lally, JM; Martin, SR; O'Reilly, NJ; Reddy, BA | 1 |
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| Berthomieu, C; Boussac, A; Brubach, JB; Díaz Quintana, AJ; Díaz-Moreno, I; Hienerwadel, R; Zuccarello, L | 1 |
| Chilton, AS; Ellis, HR; Forbes, DL; Lamb, AL; Meneely, KM | 1 |
| Echavarri-Erasun, C; Fajardo, AS; Legrand, P; Martin, L; Nicolet, Y; Payá-Tormo, LA; Pellicer Martı Nez, MT; Rubio, LM; Vernède, X | 1 |
| Guo, L; Lin, J; Lin, JF; Lin, S; Wang, Y; Yang, X | 1 |
| Boudker, O; Bracken, C; Eliezer, D; Huang, Y; Huysmans, GHM; Lv, G; Razavi, AM; Wang, X; Weinstein, H | 1 |
| Fathi-Roudsari, M; Maghsoudi, A; Maghsoudi, N; Niazi, S; Soleiman, M | 1 |
| Garza-López, RA; Gray, HB; Kozak, JJ | 1 |
| Annicchiarico-Petruzzelli, M; Candi, E; Cardillo, C; Di Daniele, N; Gentileschi, P; Lena, AM; Melino, G; Piro, MC; Rodia, G; Rovella, V; Sica, G; Tesauro, M | 1 |
| Demeler, B; Iranzo, O; Ivancich, A; Koebke, KJ; Kühl, T; Lojou, E; Pecoraro, VL; Schoepp-Cothenet, B | 1 |
| Harvey, JN; Roos, G | 1 |
| Kung, WM; Lin, MS | 1 |
| Pejić, J; Ramek, M; Sabolović, J | 1 |
| Choopanian, P; Jafari, M; Karimi, M; Kolahdooz, S; Marzabani, R; Mirzaie, M; Mozafari, N; Nieminen, AI; Rezadoost, H | 1 |
| Kashiwagi, T; Miyano, H; Mizukoshi, T; Nakata, K; Oda, Y; Yamaguchi, H | 1 |
| Chiaraluce, R; Consalvi, V; La Penna, G; Morante, S; Pasquo, A; Petrosino, M; Proux, O; Rossi, G; Stellato, F | 1 |
| Gu, Y; Hu, L; Liu, J; Liu, W; Qiao, Y; Sun, P; Wang, X; Zheng, C | 1 |
| Burnes, H; Eshleman, HD; Goldberg, MB; Lesser, CF; Levy, R; Slade, DJ; Westervelt, KA; Wood, TE; Yoon, JM | 1 |
| Anjum Zia, M; Jahan, N; Kiran, S; Mujtaba, N; Naqvi, SAR; Sultana, B | 1 |
| Cowan, JA; Guella, G; Hendricks, AL; Mansy, SS; Parkkila, T; Rossetto, D; Sang, L; Sebastianelli, L; Valer, L | 1 |
| Garner, DK; Lu, Y; Marshall, NM; Nilges, MJ; Yu, Y | 1 |
| Bochtler, M; Czapinska, H | 1 |
| Bulathge, AW; Gassensmith, JJ; Herbert, FC; Meloni, G; Villones, RLE | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Cutsail, G; DeBeer, S; Gohlke, H; Groth, G; Müller, L; Schott-Verdugo, S | 1 |
| Chen, SN; Laghari, ZA; Li, L; Nie, P; Zhang, S | 1 |
| Conlon, N; Cuskelly, DD; Dix, SH; Doyle, S; Fitzpatrick, DA; Gilmartin, CB; Jones, GW | 1 |
| Fiser, B; Olasz, B; Owen, MC; Szőri, M; Viskolcz, B | 1 |
| Bias, T; Geldenhuys, WJ; Konkle, ME; Kruger, J; Kunk, C; Mann, A; Markitan, J; Mendoza, G; Menze, MA; Nath, A | 1 |
| Chen, F; Guo, X; He, Y; Li, Y; Qin, P; Sun, A; Xiao, W; Yu, K; Zhang, M | 1 |
| Andoh, A; Fujimoto, N; Hira, D; Ikeda, Y; Inatomi, O; Isono, T; Kawahara, M; Morita, SY; Nishida, A; Noda, S; Terada, T | 1 |
| Cheng, C; Luo, D; Ma, Q; Qi, L; Qiao, J | 1 |
| Barceló-Oliver, M; Bellotti, D; Dzyhovskyi, V; Garstka, K; Kozłowski, H; Rowińska-Żyrek, M; Stokowa-Sołtys, K; Świątek-Kozłowska, J; Wątły, J | 1 |
| Ahmed, KT; Barrios, AM; Dudley, GB; Gaston, R; Wang, H | 1 |
48 review(s) available for histidine and cysteine
| Article | Year |
|---|---|
Amino acid biosynthesis and its regulation.
Topics: Amino Acids; Arginine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Histidine; Phenylalanine; Pyruvates; Serine; Tyrosine | 1978 |
8alpha-substituted flavins of biological importance: an updating.
Topics: Alcohol Oxidoreductases; Animals; Apoenzymes; Bacterial Proteins; Binding Sites; Brain; Cysteine; Cytochromes; Flavins; Flavoproteins; Histidine; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxidoreductases; Oxidoreductases, N-Demethylating; Pseudomonas; Spectrum Analysis | 1976 |
[Keratohyaline and epidermal keratihization].
Topics: Animals; Animals, Newborn; Autoradiography; Cysteine; Glucosephosphate Dehydrogenase; Guinea Pigs; Histidine; Horses; Keratins; Lipase; Lipid Metabolism; Mice; Proline; Protein Biosynthesis; Rats; RNA, Messenger; Skin; Sulfur | 1975 |
What is the role of the cys-his motif in retroviral nucleocapsid (NC) proteins?
Topics: Amino Acid Sequence; Capsid; Cysteine; Histidine; Molecular Sequence Data; Protein Conformation; Retroviridae; Sequence Homology, Nucleic Acid; Viral Core Proteins | 1989 |
8 alpha-substituted flavins of biological importance.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Chromatium; Cysteine; Cytochrome c Group; Electron Spin Resonance Spectroscopy; Flavins; Flavoproteins; Histidine; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Monoamine Oxidase; Oxidoreductases; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Zinc | 1974 |
Aldolase: a model for enzyme structure-function relationships.
Topics: Age Factors; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Crystallization; Cyanogen Bromide; Cysteine; Fructose-Bisphosphate Aldolase; Histidine; Isoenzymes; Lysine; Macromolecular Substances; Models, Chemical; Muscles; Plants; Rabbits; Saccharomyces cerevisiae; Schiff Bases; Species Specificity; Structure-Activity Relationship; Tyrosine | 1972 |
Transaldolase: a model for studies of isoenzymes and half-site enzymes.
Topics: Amino Acids; Binding Sites; Candida; Chromatography; Cysteine; Fructosephosphates; Glucose; Glycolysis; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Macromolecular Substances; Molecular Weight; Pentoses; Photochemistry; Protein Binding; Protein Conformation; Sulfhydryl Compounds; Transaldolase; Transferases | 1973 |
Metal-albumin-amino acid interactions: chemical and physiological interrelationships.
Topics: Albumins; Amino Acids; Animals; Cadmium; Chromatography, Gel; Copper; Cysteine; Dose-Response Relationship, Drug; Histidine; Humans; In Vitro Techniques; Kinetics; Male; Protein Binding; Radioisotopes; Rats; Scleroderma, Systemic; Zinc; Zinc Isotopes | 1974 |
Biochemical genetics of bacteria.
Topics: Arginine; Chromosomes, Bacterial; Cysteine; Escherichia coli; Genes; Genes, Regulator; Genetic Code; Genetics, Microbial; Histidine; Homeostasis; Isoleucine; Leucine; Methionine; Molecular Biology; Nucleosides; Operon; Purine Nucleotides; Pyrimidines; Salmonella typhimurium; Transcription, Genetic; Tryptophan; Valine | 1974 |
Biochemistry of covalently bound flavins.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Amino Acids; Animals; Bacteria; Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Cytochromes; Flavin-Adenine Dinucleotide; Flavins; Histidine; Indoles; Monoamine Oxidase; Mycotoxins; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Protein Binding; Pyrroles; Riboflavin; Succinate Dehydrogenase; Thiamine | 1974 |
The mechanism of action of aldolases.
Topics: Amino Acid Sequence; Animals; Bacteria; Binding Sites; Biological Evolution; Carbohydrate Metabolism, Inborn Errors; Cattle; Chelating Agents; Chemistry, Organic; Cysteine; Fructose; Fructose-Bisphosphate Aldolase; Genetics; Histidine; Liver; Lysine; Metals; Models, Chemical; Molecular Weight; Muscles; Organ Specificity; Organic Chemistry Phenomena; Phosphates; Rabbits; Rats; Saccharomyces; Tyrosine | 1968 |
Covalent labeling of active sites.
Topics: Amino Acid Sequence; Amino Acids; Antibodies; Binding Sites; Carbon Isotopes; Chymotrypsin; Cysteine; Haptens; Histidine; Isoflurophate; Lysine; Models, Chemical; Phosphoglucomutase; Proteins; Trypsin; Tryptophan; Tyrosine | 1967 |
[Structural data on lactate dehydrogenase isoenzymes].
Topics: Amino Acids; Animals; Binding Sites; Cattle; Coenzymes; Cysteine; Electrophoresis; Embryo, Mammalian; Histidine; Humans; Hybridization, Genetic; Hydrogen; Isoenzymes; L-Lactate Dehydrogenase; Male; Molecular Weight; Peptides; Rabbits; Rats; Spermatozoa; Testis; Tyrosine | 1970 |
Recent developments in chemical modification and sequential degradation of proteins.
Topics: Amines; Arginine; Chemical Phenomena; Chemistry; Cysteine; Histidine; Methionine; Proteins; Sulfhydryl Compounds; Sulfides; Tryptophan; Tyrosine | 1970 |
[Synthesis of peptides by solid phase method. 1].
Topics: Arginine; Asparagine; Cysteine; Esters; Glutamine; Histidine; Lysine; Methionine; Methods; Peptides; Polystyrenes; Serine; Threonine | 1971 |
[The role of zinc in the pathology of skin].
Topics: Age Factors; Animals; Colorimetry; Cysteine; Histidine; Humans; Sex Factors; Skin; Skin Diseases; Spectrophotometry; Swine; Zinc | 1971 |
Histones: structure and function.
Topics: Acetates; Acylation; Amino Acid Sequence; Animals; Arginine; Cattle; Chemical Phenomena; Chemistry; Chromatin; Cysteine; Cystine; DNA; Female; Histidine; Histones; Lysine; Male; Methylation; Molecular Weight; Oxidation-Reduction; Phosphoproteins; Phosphoric Acids; Protein Binding; Protein Conformation; RNA; Serine; Thymus Gland | 1971 |
Identification of specific amino acid residues.
Topics: Alkylating Agents; Amides; Amino Acid Sequence; Amino Acids; Arginine; Chromatography, Paper; Colorimetry; Cysteine; Cystine; Disulfides; Ethylmaleimide; Histidine; Hydroxymercuribenzoates; Indicators and Reagents; Mathematics; Mercury; Methionine; Methods; Oxidation-Reduction; Peptides; Proteins; Silver; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Tryptophan | 1970 |
Sequence determination.
Topics: Amino Acid Sequence; Amino Acids; Aminopeptidases; Apoproteins; Arginine; Autoanalysis; Carboxypeptidases; Chromatography, Paper; Chromatography, Thin Layer; Cysteine; Fluorides; Histidine; Hydantoins; Hydrolysis; Indicators and Reagents; Methods; Myoglobin; Nitrobenzenes; Proteins; Spectrophotometry, Ultraviolet; Temperature; Thiocyanates; Time Factors | 1970 |
Creatine kinase: structure-activity relationships.
Topics: Affinity Labels; Allosteric Regulation; Animals; Binding Sites; Creatine Kinase; Cysteine; Histidine; Kinetics; Magnetic Resonance Spectroscopy; Muscles; Protein Binding; Protein Conformation | 1983 |
Structure and function of the calcium pump protein of sarcoplasmic reticulum.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cysteine; Histidine; Humans; Lysine; Magnesium; Protein Conformation; Sarcoplasmic Reticulum | 1982 |
Current problems in mechanistic studies of serine and cysteine proteinases.
Topics: Aspartic Acid; Binding Sites; Catalysis; Cysteine; Cysteine Endopeptidases; Endopeptidases; Histidine; Models, Chemical; Papain; Protein Conformation; Serine Endopeptidases | 1982 |
Amino acid transport in isolated rat hepatocytes.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Catecholamines; Cell Membrane; Cells, Cultured; Cysteine; Glucagon; Glucocorticoids; Glutamine; Glycine; Histidine; In Vitro Techniques; Insulin; Kinetics; Liver; Lysine; Rats | 1982 |
Sequence-specific DNA recognition by Cys2, His2 zinc fingers.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cysteine; DNA; Histidine; Humans; Molecular Sequence Data; Zinc Fingers | 1994 |
Genetics of hemochromatosis.
Topics: Amino Acid Substitution; Aspartic Acid; Cloning, Molecular; Cysteine; Genes, MHC Class I; Genes, Recessive; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Iron; Membrane Proteins; Mutation, Missense; Tyrosine | 1999 |
Studying the structure and regulation of soluble guanylyl cyclase.
Topics: Animals; Biochemistry; Cysteine; DNA Mutational Analysis; Enzyme Activation; Guanylate Cyclase; Heme; Histidine; Isoenzymes; Solubility | 1999 |
Palladium(II) and platinum(II) complexes as synthetic peptidases.
Topics: Animals; Catalysis; Chromatography, High Pressure Liquid; Cysteine; Cytochrome c Group; Electrophoresis, Polyacrylamide Gel; Histidine; Horses; Hydrogen-Ion Concentration; Hydrolysis; Magnetic Resonance Spectroscopy; Methionine; Models, Chemical; Molecular Structure; Myoglobin; Palladium; Peptides; Platinum; Protein Conformation; Solvents; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship | 2001 |
Synthetic analogs of zinc enzymes.
Topics: Alcohol Dehydrogenase; Amidohydrolases; Amino Acid Motifs; Aminopeptidases; Animals; Aspartic Acid; Bacterial Proteins; Bicarbonates; Binding Sites; Carbonic Anhydrases; Carboxypeptidases; Catalysis; Cations, Divalent; Cysteine; Dihydroorotase; DNA Repair; Enzymes; Escherichia coli Proteins; Glutamic Acid; Histidine; Ligands; Liver; Matrix Metalloproteinases; Metalloproteins; Models, Chemical; Molecular Structure; N-Acetylmuramoyl-L-alanine Amidase; Nitrates; O(6)-Methylguanine-DNA Methyltransferase; Porphobilinogen Synthase; Spectrum Analysis; Thermolysin; Transcription Factors; Water; Zinc | 2001 |
Molecular anatomy of tyrosinase and its related proteins: beyond the histidine-bound metal catalytic center.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Catechol Oxidase; Cations; Copper; Cysteine; Glycosylation; Histidine; Melanins; Models, Biological; Models, Molecular; Molecular Sequence Data; Monophenol Monooxygenase; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Tyrosine | 2002 |
Zinc fingers--folds for many occasions.
Topics: Amino Acid Motifs; Animals; Cysteine; Histidine; Humans; Ligands; Models, Molecular; Protein Binding; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Zinc; Zinc Fingers | 2002 |
CFTR: what's it like inside the pore?
Topics: Anions; Biological Transport, Active; Cell Membrane Permeability; Cysteine; Cystic Fibrosis Transmembrane Conductance Regulator; Electrochemistry; Histidine; Ion Transport; Models, Biological | 2003 |
[Iron storage disease].
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Chromosomes, Human, Pair 6; Cysteine; Diabetes Mellitus; Diagnosis, Differential; Hemochromatosis; Histidine; Humans; Hyperpigmentation; Iron Overload; Liver Cirrhosis; Liver Neoplasms; Mass Screening; Phlebotomy; Point Mutation; Population Surveillance; Prevalence; Prognosis; Tyrosine | 2004 |
The serine acetyltransferase reaction: acetyl transfer from an acylpantothenyl donor to an alcohol.
Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Alcohols; Binding Sites; Catalysis; Cysteine; Enzyme Stability; Feedback, Physiological; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Models, Structural; Molecular Structure; Molecular Weight; Protein Binding; Protein Conformation; Protein Structure, Quaternary; Protein Structure, Secondary; Serine; Serine O-Acetyltransferase; Substrate Specificity | 2005 |
Peptidomics, current status.
Topics: Arginine; Chromatography, Affinity; Combinatorial Chemistry Techniques; Cysteine; Histidine; Humans; Lysine; Methionine; Peptides; Phosphotyrosine; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan; Tyrosine; Vascular Cell Adhesion Molecule-1 | 2005 |
Hydroxyl radical formation resulting from the interaction of nickel complexes of L-histidine, glutathione or L-cysteine and hydrogen peroxide.
Topics: Antioxidants; Benzoic Acid; Cysteine; Glutathione; Histidine; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Nickel | 2005 |
A design for life: prokaryotic metal-binding MerR family regulators.
Topics: Adenosine Triphosphatases; Bacterial Proteins; Base Sequence; Crystallography, X-Ray; Cysteine; Cytoplasm; DNA-Binding Proteins; Escherichia coli; Histidine; Hydrogen Bonding; Metals; Models, Biological; Models, Molecular; Molecular Sequence Data; Promoter Regions, Genetic; Sequence Homology, Nucleic Acid; Transcription Factors; Transcription, Genetic | 2005 |
Technologies and methods for sample pretreatment in efficient proteome and peptidome analysis.
Topics: Centrifugation; Chromatography, Affinity; Chromatography, Ion Exchange; Cysteine; Enzymes, Immobilized; Glycopeptides; Histidine; Lectins; Mass Spectrometry; Metals; Methionine; Microarray Analysis; Online Systems; Peptide Fragments; Phosphopeptides; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan; Ultrafiltration | 2008 |
In vitro assays for assessing the potential for copper complexes to function as radiopharmaceutical agents.
Topics: Blood Proteins; Copper; Crystallography, X-Ray; Cysteine; Glutathione; Histidine; In Vitro Techniques; Ions; Models, Chemical; Molecular Conformation; Oxidation-Reduction; Pharmaceutical Preparations; Potentiometry; Radiopharmaceuticals; Spectrophotometry; Sulfhydryl Compounds | 2008 |
PCSK9 as a therapeutic target of dyslipidemia.
Topics: Cysteine; Dyslipidemias; Histidine; Humans; Models, Molecular; Proprotein Convertase 9; Proprotein Convertases; Protein Conformation; Serine Endopeptidases | 2009 |
Particularly interesting cysteine- and histidine-rich protein in cardiac development and remodeling.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cysteine; DNA-Binding Proteins; Heart; Histidine; Humans; LIM Domain Proteins; Membrane Proteins; Signal Transduction; Ventricular Remodeling | 2009 |
The role of zinc in the S100 proteins: insights from the X-ray structures.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Cysteine; EF Hand Motifs; Histidine; Molecular Sequence Data; S100 Proteins; Zinc | 2011 |
Secondary interactions involving zinc-bound ligands: roles in structural stabilization and macromolecular interactions.
Topics: Carbonic Anhydrases; Cysteine; Early Growth Response Protein 1; Histidine; Humans; Hydrogen Bonding; Ligands; Metalloproteins; Models, Molecular; Nucleocapsid Proteins; Protein Binding; Protein Structure, Tertiary; TNF Receptor-Associated Factor 6; Tristetraprolin; Zinc | 2012 |
Peroxide-sensing transcriptional regulators in bacteria.
Topics: Bacteria; Cysteine; Gene Expression Regulation, Bacterial; Histidine; Oxidation-Reduction; Oxidative Stress; Peroxides; Reactive Oxygen Species; Sodium Hypochlorite; Stress, Physiological; Transcription Factors | 2012 |
Lysosomal metal, redox and proton cycles influencing the CysHis cathepsin reaction.
Topics: Autophagy; Biocatalysis; Cathepsins; Cysteine; Histidine; Lysosomes; Metals; Oxidation-Reduction; Protons | 2013 |
Designing hydrolytic zinc metalloenzymes.
Topics: Binding Sites; Carbonic Anhydrases; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; Glutamic Acid; Histidine; Hydrolysis; Metalloproteins; Models, Molecular; Protein Binding; Protein Engineering; Protein Structure, Secondary; Zinc; Zinc Fingers | 2014 |
Signaling by 4-hydroxy-2-nonenal: Exposure protocols, target selectivity and degradation.
Topics: Aldehydes; Animals; Autophagy; Cysteine; Histidine; Humans; Lipid Peroxidation; Lysine; Lysosomes; Oxidative Stress; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Signal Transduction | 2017 |
His-Cys and Trp-Cys cross-links generated by post-translational chemical modification.
Topics: Cross-Linking Reagents; Cysteine; Histidine; Protein Processing, Post-Translational; Tryptophan | 2020 |
The NFκB Antagonist CDGSH Iron-Sulfur Domain 2 Is a Promising Target for the Treatment of Neurodegenerative Diseases.
Topics: Cysteine; Histidine; Homeostasis; Humans; Iron; Iron-Sulfur Proteins; Membrane Proteins; Neurodegenerative Diseases; NF-kappa B; PPAR-beta; Protein Domains | 2021 |
1178 other study(ies) available for histidine and cysteine
| Article | Year |
|---|---|
Mercaptoimidazolylpropionic acid hydrobromide. Inhibition of tadpole collagenase and related properties.
Topics: Animals; Anura; Bacillus subtilis; Chemical Phenomena; Chemistry; Histidine; In Vitro Techniques; Larva; Magnetic Resonance Spectroscopy; Microbial Collagenase; Mutagens; Oxidation-Reduction; Rana catesbeiana; Sulfhydryl Compounds | 1978 |
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
A green fluorescent chemosensor for amino acids provides a versatile high-throughput screening (HTS) assay for proteases.
Topics: Amino Acids; Copper; Drug Evaluation, Preclinical; Endopeptidases; Fluoresceins; Fluorescence; Kinetics; Ligands; Molecular Probes | 2003 |
Comparison of amino acids bathing the oxyntic gland area in the stimulation of gastric secretion.
Topics: Amino Acids; Animals; Arginine; Atropine; Cysteine; Dogs; Fistula; Gastric Juice; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lidocaine; Metiamide; Pancreas; Pepsin A; Phenylalanine; Stimulation, Chemical; Stomach; Threonine | 1976 |
Possible occurrence for histidyl and cysteyl residues in the catalytic center of rat liver mitochondrial D (-)-beta-hydroxybutyrate dehydrogenase.
Topics: Acetoacetates; Animals; Binding Sites; Chloromercuribenzoates; Cysteine; Dicarboxylic Acids; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxybutyrate Dehydrogenase; Kinetics; Malonates; Mitochondria, Liver; Rats; Succinates | 1975 |
Affinity labeling of a previously undetected essential lysyl residue in class I fructose bisphosphate aldolase.
Topics: Affinity Labels; Amino Acids; Animals; Binding Sites; Cysteine; Dihydroxyacetone Phosphate; Ethanolamines; Fructose-Bisphosphate Aldolase; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Muscles; Organophosphorus Compounds; Protein Binding; Rabbits | 1976 |
Purification, stability and inhibition of the collagenase from Achromobacter iophagus.
Topics: Alcaligenes; Caseins; Cysteine; Edetic Acid; Ethylmaleimide; Histidine; Hydrogen-Ion Concentration; Microbial Collagenase; Temperature | 1975 |
Properties of crystalline reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase from bovine adrenocortical mitochondria. II. Essential histidyl and cysteinyl residues at the NADPH binding site of NADPH-adrenodoxin reductase.
Topics: Adrenal Cortex; Adrenal Glands; Adrenodoxin; Animals; Binding Sites; Cattle; Cysteine; Diethyl Pyrocarbonate; Ferredoxin-NADP Reductase; Glutathione; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; Light; Methylene Blue; Mitochondria; NAD; NADH, NADPH Oxidoreductases; NADP | 1976 |
Catalytic properties of peptides with hydrolytic activity.
Topics: Aspartic Acid; Binding Sites; Catalysis; Cysteine; Esterases; Histidine; Hydrogen-Ion Concentration; Isoelectric Point; Oligopeptides; Sulfhydryl Compounds; Temperature | 1976 |
Chemotaxis toward amino acids by Bdellovibrio bacteriovorus.
Topics: Amino Acids; Asparagine; Bdellovibrio; Chemotaxis; Cysteine; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Lysine; Temperature; Threonine | 1977 |
Characterization of the papain active centre by using two-protonic-state electrophiles as reactivity probes. Evidence for nucleophilic reactivity in the un-interrupted cysteine-25-histidine-159 interactive system.
Topics: 2,2'-Dipyridyl; Chemical Phenomena; Chemistry; Cysteine; Disulfides; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Papain; Spectrophotometry; Sulfhydryl Reagents | 1978 |
Crystalline reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase from pig adrenocortical mitochondria. Essential histidyl and cysteinyl residues of the NADPH-binding site and environment of the adrenodoxin-binding site.
Topics: Adrenal Cortex; Adrenodoxin; Animals; Binding Sites; Cattle; Cysteine; Diethyl Pyrocarbonate; Ferredoxin-NADP Reductase; Ferredoxins; Histidine; Mitochondria; NADH, NADPH Oxidoreductases; NADP; Sulfhydryl Reagents; Swine | 1978 |
Evidence that binding to the s2-subsite of papain may be coupled with catalytically relevant structural change involving the cysteine-25-histidine-159 diad. Kinetics of the reaction of papain with a two-protonic-state reactivity probe containing a hydroph
Topics: 2,2'-Dipyridyl; Acetonitriles; Benzoxazoles; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Cysteine; Disulfides; Enzyme Activation; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Papain; Protons; Pyridines; Sulfhydryl Compounds | 1979 |
Structure of nodules induced by auxotrophic and ineffective mutants of Rhizobium meliloti strain L5-30 requiring cysteine, arginine+uracil and histidine.
Topics: Amino Acids; Arginine; Cysteine; Histidine; Mutation; Plant Cells; Plants; Rhizobium; Symbiosis; Transduction, Genetic; Uracil | 1977 |
The inhibitory effect of cysteine on the mutagenic activities of several carcinogens.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Acrylamides; Aflatoxins; Carcinogens; Cysteine; Genetic Techniques; Histidine; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Microsomes, Liver; Mutagens; Salmonella typhimurium; Semicarbazones | 1978 |
The effect of chelation on the fate of intravenously administered cadmium in rats.
Topics: Animals; Cadmium; Chelating Agents; Cysteine; Digestive System; Dimercaprol; Edetic Acid; Female; Glutathione; Histidine; Injections, Intravenous; Kidney; Liver; Penicillamine; Rats | 1979 |
Mechanism of an active transport of calcium. Ethoxyformylation of sarcoplasmic reticulum vesicles.
Topics: Adenosine Triphosphatases; Anhydrides; Animals; Binding Sites; Biological Transport, Active; Calcium; Cysteine; Ethyl Ethers; Histidine; Kinetics; Mathematics; Muscles; Protein Binding; Rabbits; Sarcoplasmic Reticulum; Spectrophotometry, Ultraviolet | 1976 |
The behavioral effects of L-methionine and related compounds in rats and mice.
Topics: Animals; Avoidance Learning; Behavior, Animal; Betaine; Brain; Brain Chemistry; Circadian Rhythm; Conditioning, Operant; Cysteine; Electroencephalography; Eye Movements; Histidine; Homocysteine; Methionine; Mice; Mice, Inbred C57BL; Niacinamide; Rats; Serine; Sleep; Sleep, REM; Wakefulness | 1975 |
Crystalline adenylate kinase from carp muscle.
Topics: Adenylate Kinase; Amino Acids; Animals; Binding Sites; Carps; Crystallization; Cyprinidae; Cysteine; Histidine; Molecular Weight; Muscles; Peptide Fragments; Phosphotransferases | 1975 |
Evidence for a histidine and a cysteine residue in the substrate-binding site of yeast alcohol dehydrogenase.
Topics: Acetamides; Alcohol Oxidoreductases; Binding Sites; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Histidine; Molecular Weight; NAD; Yeasts | 1975 |
Purification of human placental estradiol 17 beta-dehydrogenase study of the steroid-binding site.
Topics: Binding Sites; Chromatography, Affinity; Cysteine; Estradiol Dehydrogenases; Female; Histidine; Humans; Hydroxysteroid Dehydrogenases; Methionine; Placenta; Pregnancy; Receptors, Cell Surface; Tryptophan | 1975 |
A study of the oxidation of butan-1-ol and propan-2-ol by nicotinamide-adenine dinucleotide catalysed by yeast alcohol dehydrogenase.
Topics: 1-Propanol; Alcohol Oxidoreductases; Butanols; Catalysis; Cysteine; Edetic Acid; Enzyme Activation; Histidine; Kinetics; Mathematics; NAD; Oxidation-Reduction; Temperature; Yeasts | 1975 |
Radial diffusion assay of tissue collagenase and its application in evaluation of collagenase inhibitors.
Topics: Animals; Anura; Cysteine; Edetic Acid; Fishes; Histidine; Kinetics; Lathyrism; Methods; Microbial Collagenase; Rats; Sepharose; Skin | 1977 |
On the e.s.r. determination of radical yields in X-irradiated amino acids.
Topics: Amino Acids; Cysteine; Dose-Response Relationship, Radiation; Electron Spin Resonance Spectroscopy; Free Radicals; Glycine; Histidine; Temperature | 1978 |
The case for assigning a value of approximately 4 to pKa-i of the essential histidine-cysteine interactive systems of papain, bromelain and ficin.
Topics: Bromelains; Cysteine; Endopeptidases; Histidine; Hydrogen-Ion Concentration; Kinetics; Papain; Spectrophotometry, Ultraviolet; Time Factors | 1975 |
Effect of pH on the reactivity of the carbonate radical in aqueous solution.
Topics: Carbonates; Chymotrypsin; Cysteine; Histidine; Hydrogen-Ion Concentration; Methane; Methionine; Muramidase; Penicillamine; Photochemistry; Propionates; Ribonucleases; Solutions; Tyrosine; Water | 1975 |
Chemical modification of bovine heart mitochondrial malate dehydrogenase. Selective modification of cysteine and histidine.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Cattle; Cysteine; Ethylmaleimide; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Iodoacetates; Malate Dehydrogenase; Malates; Mitochondria, Muscle; Molecular Weight; Myocardium; NAD; Oxaloacetates; Urea | 1975 |
Quantitative gas-liquid chromatography and mass spectrometry of the N(O)-perfluorobutyryl-O-isoamyl derivatives of amino acids.
Topics: Amino Acids; Amino Acids, Dicarboxylic; Butyrates; Chromatography; Chromatography, Gas; Cysteine; Cystine; Histidine; Hydrocarbons, Fluorinated; Hydrogen-Ion Concentration; Hydroxyproline; Mass Spectrometry; Methionine; Methods; Muramidase; Plant Proteins; Proline; Tryptophan | 1975 |
Nucleotide sequence of the mitochondrial structural genes for cysteine-tRNA and histidine-tRNA of yeast.
Topics: Base Sequence; Cysteine; DNA Restriction Enzymes; DNA, Mitochondrial; Histidine; Nucleic Acid Conformation; RNA, Transfer; Saccharomyces cerevisiae | 1979 |
Biotransformation of chloroform by rat and human liver microsomes; in vitro effect on some enzyme activities and mechanism of irreversible binding to macromolecules.
Topics: Animals; Biotransformation; Chloroform; Cysteine; Histidine; Humans; In Vitro Techniques; Kinetics; Macromolecular Substances; Male; Microsomes, Liver; NADH, NADPH Oxidoreductases; Oxygen Consumption; Rats | 1979 |
Triethyltin binding to cat haemoglobin. Evidence for two chemically distinct sites and a role for both histidine and cysteine residues.
Topics: Animals; Binding Sites; Cats; Chemical Phenomena; Chemistry; Cysteine; Diethyl Pyrocarbonate; Hemoglobins; Histidine; Models, Chemical; Protein Binding; Proteins; Trialkyltin Compounds; Triethyltin Compounds | 1979 |
Purification of crystallization of transaldolase isozyme I and evidence for different genetic origin of isozymes I and III in Candida utilis.
Topics: Amino Acid Sequence; Amino Acids; Ammonium Sulfate; Candida; Chemical Phenomena; Chemical Precipitation; Chemistry, Physical; Chromatography; Crystallization; Cysteine; Genetics, Microbial; Histidine; Isoenzymes; Leucine; Threonine; Transaldolase; Transferases | 1977 |
An investigation of the copper ion environments of azurin and spinach plastocyanin by 1H N.M.R. spectroscopy.
Topics: Azurin; Bacterial Proteins; Binding Sites; Copper; Cysteine; Histidine; Magnetic Resonance Spectroscopy; Plant Proteins; Plastocyanin | 1978 |
Urinary zinc excretion following infusions of zinc sulfate, cysteine, histidine, or glycine.
Topics: Animals; Cysteine; Dogs; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Glycine; Histidine; Infusions, Parenteral; Kidney; Zinc | 1978 |
General and specific effects of amino acid starvation on the formation of undermodified Escherichia coli phenylalanine tRNA.
Topics: Amino Acids; Base Sequence; Cysteine; Escherichia coli; Histidine; Leucine; Methionine; Nucleic Acid Conformation; Phenylalanine; RNA, Transfer; Species Specificity; Transcription, Genetic | 1976 |
A gas--liquid chromatographic-isotope dilution analysis of cysteine, histidine, and tryptophan in acid-hydrolyzed protein.
Topics: Carbon Radioisotopes; Chromatography, Gas; Cysteine; Gas Chromatography-Mass Spectrometry; Histidine; Muramidase; Proteins; Radioisotope Dilution Technique; Tryptophan | 1976 |
Antitumor agents. 21. A proposed mechanism for inhibition of cancer growth by tenulin and helenalin and related cyclopentenones.
Topics: Animals; Antineoplastic Agents, Phytogenic; Ascitic Fluid; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Chromatin; Cyclopentanes; Cysteine; DNA, Neoplasm; Glutathione; Histidine; Lactones; Leukemia, Experimental; Leukemia, Lymphoid; Male; Mice; Mice, Inbred DBA; Neoplasm Proteins; Rats; Sesquiterpenes; Sesquiterpenes, Guaiane; Spectrophotometry, Ultraviolet; Time Factors | 1977 |
Intramolecular catalysis of acylation and deacylation in peptides containing cysteine and histidine.
Topics: Acylation; Catalysis; Cysteine; Histidine; Peptides | 1977 |
Sequential chemical modification of a histidyl and a cysteinyl residue in bacterial luciferase.
Topics: Bacteria; Binding Sites; Cysteine; Enzyme Activation; Flavin Mononucleotide; Histidine; Kinetics; Luciferases; Protein Binding; Sulfhydryl Compounds | 1977 |
Negatively charged reactants as probes in the study of the essential mercaptide-imidazolium ion-pair of thiolenzymes.
Topics: Alkylation; Anions; Binding Sites; Catalysis; Cysteine; Histidine; Iodoacetates; Kinetics; Papain; Propionates; Subtilisins | 1977 |
American Academy of Pediatrics. Committee on Nutrition: special diets for infants with inborn errors of amino acid metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Cysteine; Histidine; Homocystinuria; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Methionine; Nutritional Requirements; Phenylalanine; Phenylketonurias; Risk; Tyrosine; Valine | 1976 |
Specificity of ethacrynic acid as a sulfhydryl reagent.
Topics: Cysteine; Ethacrynic Acid; Histidine; Imidazoles; L-Lactate Dehydrogenase; Lysine; Serine; Sulfhydryl Reagents | 1976 |
[Structure of nitroso pigments in meats].
Topics: Amino Acids; Ascorbic Acid; Chemical Phenomena; Chemistry; Cysteine; Food Preservation; Heme; Histidine; Meat; Models, Chemical; Nitroso Compounds; Pigments, Biological; Pyrroles | 1976 |
Radiation-induced binding of some protein and nucleic acid constituents with macromolecular components in cell systems.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Cell Line; Cobalt Radioisotopes; Cysteine; Cystine; Cytosine; Dose-Response Relationship, Radiation; Escherichia coli; Gamma Rays; Histidine; Leukemia, Lymphoid; Macromolecular Substances; Methionine; Mice; Phenylalanine; Protein Binding; Purines; Pyrimidines; Radiation Effects; Sulfur Radioisotopes; Thymine; Tritium; Tryptophan; Tyrosine; Uracil | 1975 |
Isolation of a peptide containing a histidinyl-cysteinyl sequence from the active center of transaldolase.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Candida; Carboxypeptidases; Chromatography, Ion Exchange; Cysteine; Histidine; Isoenzymes; Pepsin A; Peptide Fragments; Transaldolase; Transferases; Trypsin | 1975 |
Further investigations on M. leprae. Growth promotion and inhibition by organic substances and observations on antagonistic and syntergistic effects.
Topics: Cysteine; Deferoxamine; Dimethyl Sulfoxide; Drug Antagonism; Drug Synergism; Glutamates; Glutamine; Histidine; Mycobacterium leprae; Purines; Pyrimidines; Tryptophan | 1975 |
Specific cyanylation and cleavage at cysteine-104 human hemoglobin alpha-chain. A novel approach to the problem of the alpha-chain tryptic core in the study of haemoglobin variants by "fingerprinting" methods.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Cyanides; Cysteine; Hemoglobins; Hemoglobins, Abnormal; Histidine; Humans; Hydrolysis; Pepsin A; Peptide Fragments; Protein Conformation; Trypsin | 1975 |
Some chemical properties of carboxymethyl derivatives of amino acids.
Topics: Amino Acids; Binding Sites; Cysteine; Histidine; Iodoacetates; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Molecular Conformation; Time Factors; Tritium | 1975 |
The absorption of iron, with or without supplements of single amino acids and of ascorbic acid, in healthy and Fe-deficient children.
Topics: Amino Acids; Anemia, Hypochromic; Ascorbic Acid; Blood Proteins; Child; Child, Preschool; Cysteine; Cystine; Egypt; Glutamates; Hematocrit; Hemoglobins; Histidine; Humans; Infant; Intestinal Absorption; Iron; Protein Binding; Transferrin; Valine | 1975 |
Evaluation of protein nutrition by metabolizable protein and urea fermentation potential.
Topics: Amino Acids; Animal Feed; Animals; Arginine; Body Composition; Cattle; Cysteine; Dietary Proteins; Edible Grain; Female; Fermentation; Histidine; Lactation; Lysine; Methionine; Nutritional Requirements; Pregnancy; Rumen; Silage; Urea; Zea mays | 1975 |
Ligand-exchange chromatography of amino acids on copper-, cobalt- and zinc-chelex 100.
Topics: Amino Acids; Ammonia; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Cobalt; Copper; Cysteine; Glutamates; Histidine; Ion Exchange Resins; Ligands; Lysine; Phenylalanine; Quaternary Ammonium Compounds; Serine; Threonine; Tyrosine; Zinc | 1975 |
Fast electron reactions in concentrated solutions of amino acids and nucleotides.
Topics: Adenosine Monophosphate; Amino Acids; Arginine; Cystamine; Cysteine; Cystine; Cytosine Nucleotides; Electrons; Glycine; Guanine Nucleotides; Histidine; Muramidase; Nucleotides; Radiation Effects; RNA; Uracil Nucleotides | 1975 |
Alteration of functional properties associated with the change in quaternary structure in unliganded haemoglobin.
Topics: Arginine; Aspartic Acid; Binding Sites; Cysteine; Hemoglobins; Histidine; Humans; Ligands; Oxygen; Oxyhemoglobins; Phytic Acid; Protein Conformation; Structure-Activity Relationship; Sulfhydryl Compounds; Tyrosine | 1975 |
Improved separation of the methyl- and phenylthiohydantoins of arginine, cysteic acid and histidine by micropolyamide thin-layer chromatography.
Topics: Arginine; Chromatography, Thin Layer; Cysteine; Histidine; Hydantoins; Phenylthiohydantoin; Thiohydantoins | 1975 |
[Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
Topics: Alanine; Amino Acids; Amniotic Fluid; Cysteine; Female; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Primary structure of streptococcal proteinase. III. Isolation of cyanogen bromide peptides: complete covalent structure of the polypeptide chain.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Cyanogen Bromide; Cysteine; Histidine; Papain; Peptide Fragments; Peptide Hydrolases; Protein Conformation; Streptococcus; Trypsin | 1976 |
[Comparison of the histochemical bases of epidermis differentiation in vertebrates].
Topics: Amphibians; Animals; Arginine; Cysteine; Cystine; Histidine; Histocytochemistry; Humans; Lysine; Mammals; Proteins; Reptiles; Skin | 1976 |
Characterization of the roles of conserved cysteine and histidine residues in poliovirus 2A protease.
Topics: Amino Acid Sequence; Base Sequence; Cysteine; Disulfides; DNA, Viral; Endopeptidases; Histidine; Ligands; Metals; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Poliovirus; Protein Processing, Post-Translational; Sequence Alignment | 1992 |
Structural details of ribonuclease H from Escherichia coli as refined to an atomic resolution.
Topics: Amino Acid Sequence; Computer Graphics; Crystallography; Cysteine; Escherichia coli; Histidine; Hydrogen Bonding; Magnesium; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Conformation; Ribonuclease H; Solubility; Tryptophan; Water; X-Ray Diffraction | 1992 |
Potential ligands to the [2Fe-2S] Rieske cluster of the cytochrome bc1 complex of Rhodobacter capsulatus probed by site-directed mutagenesis.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport Complex III; Histidine; Iron-Sulfur Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Photosynthesis; Protein Conformation; Rhodobacter capsulatus; Sequence Homology, Nucleic Acid | 1992 |
His92Ala mutation in ribonuclease T1 induces segmental flexibility. An X-ray study.
Topics: Adenosine Monophosphate; Alanine; Amino Acid Sequence; Catalysis; Cysteine; Guanine; Guanosine Monophosphate; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Ribonuclease T1; Structure-Activity Relationship; Temperature; Valine; X-Ray Diffraction | 1992 |
Immobilized metal ion affinity chromatography of serum albumins.
Topics: Animals; Chromatography, Affinity; Cysteine; Dogs; Histidine; Humans; Metals; Serum Albumin; Serum Albumin, Bovine; Tryptophan | 1991 |
Evidence for an essential histidine residue in 4S-limonene synthase and other terpene cyclases.
Topics: Binding Sites; Cysteine; Diethyl Pyrocarbonate; Histidine; Intramolecular Lyases; Isomerases; Kinetics; Plants; Rose Bengal | 1992 |
Identification of the active site residues in the nsP2 proteinase of Sindbis virus.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Cysteine; Cysteine Endopeptidases; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Papain; Protein Biosynthesis; RNA, Viral; Sequence Homology, Amino Acid; Sindbis Virus; Tryptophan; Viral Nonstructural Proteins; Virulence | 1992 |
Evidence for two histidine ligands at the diiron site of methane monooxygenase.
Topics: Apoenzymes; Binding Sites; Circular Dichroism; Cysteine; Diethyl Pyrocarbonate; Histidine; Iron; Kinetics; Methylococcaceae; Oxygenases; Protein Structure, Secondary; Thiocyanates | 1992 |
Immobilized metal ion affinity chromatography of synthetic peptides. Binding via the alpha-amino group.
Topics: Amino Acid Sequence; Buffers; Cations, Divalent; Chromatography, Affinity; Copper; Cysteine; Histidine; Hydrogen-Ion Concentration; Molecular Sequence Data; Nickel; Peptides; Tryptophan | 1992 |
The role of anticodon bases and the discriminator nucleotide in the recognition of some E. coli tRNAs by their aminoacyl-tRNA synthetases.
Topics: Amino Acyl-tRNA Synthetases; Anticodon; Asparagine; Bacteriophage T7; Base Sequence; Cysteine; DNA-Directed RNA Polymerases; Escherichia coli; Glycine; Histidine; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Transfer; Serine; Structure-Activity Relationship; Substrate Specificity | 1992 |
The zinc finger motif. Conservation of chemical shifts and correlation with structure.
Topics: Amino Acid Sequence; Biological Evolution; Cysteine; Histidine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Protein Conformation; Sequence Homology, Nucleic Acid; Transcription Factor TFIIIA; Transcription Factors; Zinc Fingers | 1992 |
Utilization of an active serine 101----cysteine mutant to demonstrate the proximity of the catalytic serine 101 and histidine 237 residues in thioesterase II.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cysteine; DNA; Fatty Acid Synthases; Histidine; Kinetics; Mass Spectrometry; Molecular Sequence Data; Mutation; Propane; Rats; Serine; Thiolester Hydrolases | 1992 |
Mutations in two cysteine-histidine-rich clusters in adenovirus type 2 DNA polymerase affect DNA binding.
Topics: Adenoviridae; Amino Acid Sequence; Animals; Blotting, Western; CCAAT-Enhancer-Binding Proteins; Cell Line; Chlorocebus aethiops; Cysteine; DNA Replication; DNA-Binding Proteins; DNA-Directed DNA Polymerase; DNA, Viral; HeLa Cells; Histidine; Humans; Molecular Sequence Data; Mutagenesis, Insertional; NFI Transcription Factors; Nuclear Proteins; Plasmids; Transcription Factors; Tumor Cells, Cultured; Y-Box-Binding Protein 1 | 1992 |
Photooxidation of skeletal muscle sarcoplasmic reticulum induces rapid calcium release.
Topics: Adenosine Triphosphatases; Animals; Calcium; Cysteine; Diethyl Pyrocarbonate; Histidine; Kinetics; Muscles; Photochemistry; Rabbits; Rose Bengal; Sarcoplasmic Reticulum | 1992 |
Chemical modification of cysteinyl, lysyl and histidyl residues of mouse liver 17 beta-hydroxysteroid dehydrogenase.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Binding Sites; Coenzymes; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Histidine; Ligands; Liver; Lysine; Mice; Protein Binding; Spectrum Analysis; Structure-Activity Relationship; Trinitrobenzenesulfonic Acid | 1992 |
Golgi retention of a trans-Golgi membrane protein, galactosyltransferase, requires cysteine and histidine residues within the membrane-anchoring domain.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chromosome Deletion; Cysteine; Fluorescent Antibody Technique; Genetic Vectors; Golgi Apparatus; Histidine; Humans; Intracellular Membranes; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Acetyllactosamine Synthase; Plasmids; Restriction Mapping; Transfection | 1992 |
Specific amino acid sequences required for O6-methylguanine-DNA methyltransferase activity: analyses of three residues at or near the methyl acceptor site.
Topics: Amino Acid Sequence; Cysteine; Drug Resistance; Escherichia coli; Histidine; Humans; Methylnitronitrosoguanidine; Methyltransferases; Molecular Sequence Data; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Valine | 1992 |
Effect of group-selective modification reagents on arylamine N-acetyltransferase activities.
Topics: Animals; Arginine; Arylamine N-Acetyltransferase; Binding Sites; Cricetinae; Cysteine; Diethyl Pyrocarbonate; Enzyme Activation; Ethylmaleimide; Histidine; Hydroxylamine; Hydroxylamines; Liver; Male; Mesocricetus; Phenylglyoxal | 1992 |
Replacement of arginine 773 by cysteine or histidine in the human androgen receptor causes complete androgen insensitivity with different receptor phenotypes.
Topics: Adolescent; Arginine; Base Sequence; Canada; Cysteine; Deoxyribonucleases, Type II Site-Specific; Disorders of Sex Development; Female; Histidine; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation; Pedigree; Phenotype; Polymerase Chain Reaction; Receptors, Androgen; Transcriptional Activation | 1992 |
Site-directed mutagenesis of glutathione S-transferase YaYa: functional studies of histidine, cysteine, and tryptophan mutants.
Topics: Animals; Base Sequence; Binding Sites; Cloning, Molecular; Cysteine; Cytosol; Enzyme Stability; Escherichia coli; Glutathione Transferase; Histidine; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Protein Conformation; Rats; Recombinant Proteins; Spectrometry, Fluorescence; Thermodynamics; Tryptophan | 1992 |
Evidence for essential histidine and cysteine residues in calcium/calmodulin-sensitive cyclic nucleotide phosphodiesterase.
Topics: Animals; Brain; Catalysis; Cattle; Cyclic Nucleotide Phosphodiesterases, Type 1; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Enzyme Activation; Ethylmaleimide; Histidine; Hydrogen-Ion Concentration; Kinetics; Phosphoric Diester Hydrolases; Spectrophotometry, Ultraviolet | 1991 |
Raman spectroscopic study on the structure of ribonuclease F1 and the binding mode of inhibitor.
Topics: Amino Acid Sequence; Binding, Competitive; Cations; Cysteine; Disulfides; Fusarium; Guanosine Monophosphate; Histidine; Hydrogen Bonding; Protein Conformation; Ribonuclease T1; Spectrum Analysis, Raman; Stereoisomerism; Tyrosine | 1991 |
Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo- and a Cys-His domain.
Topics: Amino Acid Sequence; Animals; Base Sequence; Caenorhabditis; Cloning, Molecular; Cysteine; DNA; DNA-Binding Proteins; Enhancer Elements, Genetic; Escherichia coli; Genes, Homeobox; Histidine; Homeodomain Proteins; Insulin; LIM-Homeodomain Proteins; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Rats; Recombinant Fusion Proteins; RNA; Sequence Homology, Nucleic Acid; Transcription Factors | 1990 |
Evidence for a "cysteine-histidine box" metal-binding site in an Escherichia coli aminoacyl-tRNA synthetase.
Topics: Alanine-tRNA Ligase; Amino Acid Sequence; Blotting, Western; Carrier Proteins; Cysteine; Escherichia coli; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; RNA; Spectrophotometry, Atomic; Structure-Activity Relationship; Zinc | 1991 |
Structural determinants of Cys2His2 zinc fingers.
Topics: Amino Acid Sequence; Cysteine; DNA-Binding Proteins; Histidine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutation; Peptides; Protein Conformation; Recombinant Proteins; Zinc Fingers | 1992 |
Covalent modification and active site-directed inactivation of a low molecular weight phosphotyrosyl protein phosphatase.
Topics: Animals; Arginine; Arsenicals; Binding Sites; Binding, Competitive; Cattle; Cyclohexanones; Cysteine; Epoxy Compounds; Glutathione; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Iodoacetates; Iodoacetic Acid; Kinetics; Molecular Weight; Phenylglyoxal; Protein Tyrosine Phosphatases | 1992 |
Non-essentiality of cysteine and histidine residues for the activity of human class PI glutathione S-transferase.
Topics: Base Sequence; Cysteine; Dinitrochlorobenzene; DNA; Escherichia coli; Ethacrynic Acid; Glutathione Transferase; Histidine; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Structure-Activity Relationship; Transfection | 1991 |
Chemical modification of PABA synthase.
Topics: Arginine; Cysteine; Diethyl Pyrocarbonate; Escherichia coli; Folic Acid; Histidine; Iodoacetamide; Phenylglyoxal; Sulfhydryl Reagents; Tetranitromethane; Transaminases; Tyrosine | 1991 |
Zinc uptake by proximal cells isolated from rabbit kidney: effects of cysteine and histidine.
Topics: Animals; Biological Transport, Active; Cadmium; Copper; Cysteine; Histidine; In Vitro Techniques; Kidney Tubules, Proximal; Kinetics; Ligands; Male; Rabbits; Zinc | 1991 |
Purification of synthetic peptides. Immobilized metal ion affinity chromatography (IMAC).
Topics: Amino Acid Sequence; Amino Acids; Antigens, Differentiation, B-Lymphocyte; Antimicrobial Cationic Peptides; Cellulase; Chelating Agents; Chromatography, Affinity; Cysteine; Histidine; Insect Hormones; Ion Exchange Resins; Metals; Molecular Sequence Data; Peptides; Receptors, Fc; Receptors, IgE; Ribonucleotide Reductases; Tryptophan | 1991 |
Primary structure and expression of a chicken cDNA encoding a protein with zinc-finger motifs.
Topics: Alpharetrovirus; Amino Acid Sequence; Animals; Avian Proteins; Base Sequence; Blotting, Northern; Cell Transformation, Viral; Chickens; Cloning, Molecular; Cysteine; DNA-Binding Proteins; Gene Expression; Genomic Library; Histidine; Molecular Sequence Data; RNA Probes; Zinc Fingers | 1991 |
Formation of difluorothionoacetyl-protein adducts by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine metabolites: nucleophilic catalysis of stable lysyl adduct formation by histidine and tyrosine.
Topics: Amines; Amino Acids; Animals; Carbon Isotopes; Carbon-Sulfur Lyases; Cysteine; Cytosol; Fluorine; Histidine; Hydrocarbons, Fluorinated; Kidney Cortex; Kidney Tubules, Proximal; Kinetics; Lyases; Lysine; Magnetic Resonance Spectroscopy; Male; Phenols; Protein Binding; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Spectrometry, Mass, Fast Atom Bombardment; Tyrosine | 1991 |
Purification and characterization of purine nucleoside phosphorylase from developing embryos of Hyalomma dromedarii.
Topics: Amino Acids; Animals; Chromatography, DEAE-Cellulose; Cysteine; Electrophoresis, Polyacrylamide Gel; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Nucleosides; Oxidation-Reduction; Purine-Nucleoside Phosphorylase; Substrate Specificity; Sulfhydryl Reagents; Ticks | 1991 |
Alteration of human myoglobin proximal histidine to cysteine or tyrosine by site-directed mutagenesis: characterization and their catalytic activities.
Topics: Bacteriophages; Cysteine; Genetic Vectors; Histidine; Humans; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Myoglobin; Oxidation-Reduction; Spectrophotometry; Styrene; Styrenes; Tyrosine | 1991 |
A unique bipartite cysteine-histidine motif defines a subfamily of potential zinc-finger proteins.
Topics: Amino Acid Sequence; Cysteine; Histidine; Molecular Sequence Data; Zinc Fingers | 1991 |
EXAFS analysis of the pH dependence of the blue-copper site in amicyanin from Thiobacillus versutus.
Topics: Bacterial Proteins; Cysteine; Electron Probe Microanalysis; Fourier Analysis; Histidine; Hydrogen-Ion Concentration; Oxidation-Reduction; Protein Conformation; Thiobacillus | 1991 |
A comparison of the active site of maltase-glucoamylase from the brush border of rabbit small intestine and kidney by chemical modification studies.
Topics: alpha-Glucosidases; Animals; Binding Sites; Cysteine; Female; Histidine; Indicators and Reagents; Intestinal Mucosa; Intestine, Small; Kidney Cortex; Kinetics; Male; Microvilli; Rabbits; Regression Analysis; Tryptophan | 1991 |
The identification of a structurally important cysteine residue in the glycerol dehydrogenase from Bacillus stearothermophilus.
Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cobalt; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Geobacillus stearothermophilus; Histidine; Iodoacetates; Iodoacetic Acid; Kinetics; Macromolecular Substances; Methyl Methanesulfonate; Molecular Weight; Peptide Fragments; Sugar Alcohol Dehydrogenases; Tritium; Trypsin; Zinc | 1991 |
Singlet oxygen production from the reactions of ozone with biological molecules.
Topics: Antioxidants; Ascorbic Acid; Cysteine; Free Radicals; Histidine; Luminescent Measurements; Methionine; NAD; NADP; Ozone; Solvents; Uric Acid | 1991 |
Point mutations in the proximal Cys-His box of Rous sarcoma virus nucleocapsid protein.
Topics: Amino Acid Sequence; Animals; Avian Sarcoma Viruses; Capsid; Cells, Cultured; Chick Embryo; Cysteine; Gene Products, gag; Genes, Viral; Histidine; Molecular Sequence Data; Mutation; Oligonucleotide Probes; RNA, Viral; Transfection; Viral Core Proteins; Viral Proteins; Virion | 1990 |
Rapid and sensitive techniques for identification and analysis of 'reactive-centre' mutants of C1-inhibitor proteins contained in type II hereditary angio-oedema plasmas.
Topics: Angioedema; Codon; Complement C1 Inactivator Proteins; Cysteine; Histidine; Humans; Mutation; Peptide Fragments; Sepharose; Trypsin | 1990 |
A tetrahedral zinc(II)-binding site introduced into a designed protein.
Topics: Amino Acid Sequence; Binding Sites; Carrier Proteins; Cations, Divalent; Circular Dichroism; Cloning, Molecular; Cobalt; Cysteine; Histidine; Metalloproteins; Molecular Sequence Data; Protein Conformation; Recombinant Proteins; Spectrophotometry; Structure-Activity Relationship; Zinc | 1990 |
Evidence that conserved residues Cys-62 and Cys-154 within the Azotobacter vinelandii nitrogenase MoFe protein alpha-subunit are essential for nitrogenase activity but conserved residues His-83 and Cys-88 are not.
Topics: Amino Acid Sequence; Azotobacter; Cysteine; Histidine; Molecular Sequence Data; Molybdoferredoxin; Mutagenesis, Site-Directed; Nitrogenase; Sequence Homology, Nucleic Acid | 1990 |
Sodium-dependent neutral amino acid transport by human liver plasma membrane vesicles.
Topics: Adult; Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Cell Membrane; Cysteine; Glutamine; Histidine; Humans; Kinetics; Liver; Sodium | 1990 |
Essential carboxy groups in xylanase A.
Topics: Basidiomycota; Binding Sites; Carbodiimides; Catalysis; Cysteine; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Schizophyllum; Tyrosine; Xylan Endo-1,3-beta-Xylosidase | 1990 |
Chemical modification of the two histidine and single cysteine residues in the channel-forming domain of colicin E1.
Topics: Amino Acid Sequence; Colicins; Cysteine; Electric Conductivity; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Ion Channels; Membrane Potentials; Peptide Fragments; Trypsin | 1986 |
Site-directed mutation of the Escherichia coli ada gene: effects of substitution of methyl acceptor cysteine-321 by histidine in Ada protein.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Galactosidase; Blotting, Western; Cysteine; DNA, Recombinant; Escherichia coli; Escherichia coli Proteins; Genes; Genes, Bacterial; Histidine; Methyltransferases; Molecular Sequence Data; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Plasmids; Restriction Mapping; Transcription Factors; Transcription, Genetic | 1989 |
The beta subunit of tryptophan synthase. Clarification of the roles of histidine 86, lysine 87, arginine 148, cysteine 170, and cysteine 230.
Topics: Arginine; Binding Sites; Cloning, Molecular; Cysteine; DNA Mutational Analysis; Histidine; Lysine; Pyridoxal Phosphate; Recombinant Proteins; Salmonella typhimurium; Spectrum Analysis; Tryptophan Synthase | 1989 |
Nutrient interactions with total parenteral nutrition: effect of histidine and cysteine intake on urinary zinc excretion.
Topics: Cysteine; Histidine; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Parenteral Nutrition, Total; Spectrophotometry, Atomic; Zinc | 1989 |
Three-dimensional solution structure of a single zinc finger DNA-binding domain.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cysteine; DNA; DNA-Binding Proteins; Histidine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Metalloproteins; Molecular Sequence Data; Molecular Structure; Protein Conformation; Solutions; Thermodynamics; Xenopus; Zinc | 1989 |
Zinc uptake by isolated rat enterocytes: effect of low molecular weight ligands.
Topics: Albumins; Animals; Cysteine; Edetic Acid; Histidine; Intestinal Absorption; Intestinal Mucosa; Kinetics; Male; Molecular Weight; Rats; Rats, Inbred Strains; Zinc | 1989 |
Zinc release from Xenopus transcription factor IIIA induced by chemical modifications.
Topics: Animals; Cysteine; Histidine; Oocytes; Phenylmercury Compounds; Protein Conformation; Spectrometry, Fluorescence; Sulfhydryl Compounds; Transcription Factor TFIIIA; Transcription Factors; Xenopus laevis; Zinc | 1989 |
A cysteine-histidine-aspartate catalytic triad is involved in glutamine amide transfer function in purF-type glutamine amidotransferases.
Topics: Amino Acid Sequence; Anthranilate Synthase; Aspartic Acid; Binding Sites; Cysteine; Escherichia coli; Histidine; Molecular Sequence Data; Mutation; Nitrogenous Group Transferases; Transferases | 1989 |
Capacitation of hamster spermatozoa with the divalent cation chelators D-penicillamine, L-histidine, and L-cysteine in a protein-free culture medium.
Topics: Animals; Cations, Divalent; Chelating Agents; Cricetinae; Culture Media; Cysteine; Epididymis; Female; Fertilization in Vitro; Histidine; Male; Penicillamine; Sperm Capacitation; Zinc | 1989 |
Zinc environment in sheep liver sorbitol dehydrogenase.
Topics: Animals; Binding Sites; Cysteine; Fourier Analysis; Histidine; L-Iditol 2-Dehydrogenase; Ligands; Liver; Nitrogen; Sheep; Spectrum Analysis; Sugar Alcohol Dehydrogenases; Sulfur; X-Rays; Zinc | 1989 |
Properties of a copper-containing cytochrome ba3: a second terminal oxidase from the extreme thermophile Thermus thermophilus.
Topics: Copper; Cysteine; Cytochrome b Group; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Histidine; Oxidation-Reduction; Thermus | 1988 |
Conserved cysteine and histidine residues of the avian myeloblastosis virus nucleocapsid protein are essential for viral replication but are not "zinc-binding fingers".
Topics: Avian Leukosis Virus; Avian Myeloblastosis Virus; Base Sequence; Capsid; Circular Dichroism; Cysteine; Histidine; Mutation; Protein Conformation; Viral Core Proteins; Virus Replication; Zinc | 1988 |
Mechanism of adenylate kinase. Histidine-36 is not directly involved in catalysis, but protects cysteine-25 and stabilizes the tertiary structure.
Topics: Adenylate Kinase; Animals; Binding Sites; Catalysis; Chickens; Cysteine; DNA Mutational Analysis; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Phosphotransferases; Protein Conformation; Protein Denaturation; Recombinant Proteins; Structure-Activity Relationship; Thermodynamics | 1988 |
Characteristics of histidine uptake by human placental microvillous membrane vesicles.
Topics: Aminoisobutyric Acids; Anions; Biological Transport, Active; Cations; Cysteine; Ethylmaleimide; Female; Gluconates; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Microvilli; Osmolar Concentration; Phenylalanine; Placenta; Pregnancy; Sodium; Temperature | 1989 |
Comparison of heme environments and proximal ligands in peroxidases and other hemoproteins through carbon-13 nuclear magnetic resonance spectroscopy of carbon monoxide complexes.
Topics: Carbon Monoxide; Chloride Peroxidase; Cysteine; Cytochrome-c Peroxidase; Heme; Hemeproteins; Histidine; Horseradish Peroxidase; Imidazoles; Isoenzymes; Lactoperoxidase; Magnetic Resonance Spectroscopy; Myoglobin; Peroxidases | 1985 |
Inactivation of 3 alpha-hydroxysteroid dehydrogenase by superoxide radicals. Modification of histidine and cysteine residues causes the conformational change.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Amino Acids; Cysteine; Free Radicals; Histidine; NAD; Protein Conformation; Serum Albumin, Bovine; Spectrometry, Fluorescence; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1986 |
Substitutions in the active site of chloramphenicol acetyltransferase: role of a conserved aspartate.
Topics: Alanine; Arginine; Asparagine; Aspartic Acid; Binding Sites; Chloramphenicol; Chloramphenicol O-Acetyltransferase; Cysteine; Drug Stability; Escherichia coli; Histidine; Hot Temperature; Hydrogen Bonding; Kinetics; Mutation; Structure-Activity Relationship; Sulfhydryl Reagents | 1988 |
The increase by spermidine of fidelity of protamine synthesis in a wheat-germ cell-free system.
Topics: Arginine; Cell-Free System; Centrifugation, Density Gradient; Cysteine; Histidine; Lysine; Peptide Biosynthesis; Protamines; RNA, Messenger; RNA, Transfer, Amino Acyl; Spermidine; Threonine; Triticum | 1986 |
Amino acid requirements of Eikenella corrodens.
Topics: Amino Acids; Arginine; Bacteroides; Culture Media; Cysteine; Eikenella corrodens; Histidine; Humans; Lysine; Proline; Tyrosine | 1986 |
Aromatic boronic acids as probes of the catalytic site of human plasma lecithin-cholesterol acyltransferase.
Topics: Binding Sites; Boronic Acids; Catalysis; Chromatography; Cysteine; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Phenylmethylsulfonyl Fluoride; Phosphatidylcholine-Sterol O-Acyltransferase; Serine | 1987 |
S-phosphocysteine and phosphohistidine are intermediates in the phosphoenolpyruvate-dependent mannitol transport catalyzed by Escherichia coli EIIMtl.
Topics: Binding Sites; Biological Transport, Active; Cysteine; Escherichia coli; Escherichia coli Proteins; Histidine; Mannitol; Monosaccharide Transport Proteins; Phosphoenolpyruvate; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation | 1988 |
Single amino acid substitutions in the reactive site of antithrombin leading to thrombosis. Congenital substitution of arginine 393 to cysteine in antithrombin Northwick Park and to histidine in antithrombin Glasgow.
Topics: Amino Acid Sequence; Antithrombin III; Arginine; Cyanogen Bromide; Cysteine; Genetic Variation; Histidine; Humans; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Serine Endopeptidases; Thrombosis; Trypsin | 1988 |
Metal binding 'finger' structures in the glucocorticoid receptor defined by site-directed mutagenesis.
Topics: Amino Acid Sequence; Cell Line; Cysteine; Gene Expression Regulation; HeLa Cells; Histidine; Humans; Molecular Sequence Data; Mutation; Receptors, Glucocorticoid; Transfection; Zinc | 1988 |
Structure of azurin from Alcaligenes denitrificans refinement at 1.8 A resolution and comparison of the two crystallographically independent molecules.
Topics: Alcaligenes; Azurin; Bacterial Proteins; Copper; Crystallization; Cysteine; Histidine; Hydrogen Bonding; Models, Molecular; Protein Conformation; Sulfates; X-Ray Diffraction | 1988 |
Chemical modification of histidine, tyrosine, tryptophan and cysteine residues in carp (Cyprinus carpio) muscle enolase.
Topics: Amino Acids; Animals; Bromosuccinimide; Carps; Cyprinidae; Cysteine; Diethyl Pyrocarbonate; Histidine; Muscles; Nitrogen; Phosphopyruvate Hydratase; Tetranitromethane; Tryptophan; Tyrosine | 1987 |
Evidence for catalytic site cysteine and histidine by chemical modification of beta-hydroxy-beta-methylglutaryl-coenzyme A reductase.
Topics: Acyl Coenzyme A; Affinity Labels; Animals; Binding Sites; Cysteine; Histidine; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Rats; Saccharomyces cerevisiae; Sulfhydryl Reagents; Temperature | 1986 |
The inhibition and disposition of intestinal alkaline phosphatase.
Topics: Alkaline Phosphatase; Allosteric Site; Amino Acids; Animals; Binding Sites; Cysteine; Histidine; Hydrogen-Ion Concentration; Intestines; Kinetics; Phenylalanine; Salmonidae; Trout; Zinc | 1987 |
Reactivity of small thiolate anions and cysteine-25 in papain toward methyl methanethiosulfonate.
Topics: Anions; Cysteine; Histidine; Hydrogen-Ion Concentration; Kinetics; Malates; Mathematics; Methyl Methanesulfonate; Papain; Protein Binding; Sulfhydryl Compounds | 1986 |
Zinc intestinal absorption in rats: specificity of amino acids as ligands.
Topics: Acetylcysteine; Amino Acids; Animals; Colon; Cysteine; Histidine; Ileum; Imidazoles; Indoles; Intestinal Absorption; Jejunum; Kinetics; Male; Proline; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Tryptophan; Zinc | 1986 |
Potentiation by sulfide of hydrogen peroxide-induced killing of Escherichia coli.
Topics: Cysteine; Drug Synergism; Escherichia coli; Histidine; Hydrogen Peroxide; Hydrogen Sulfide; Iron | 1985 |
Isolation and characterization of the ram spermatidal nuclear proteins P1, 3 and T.
Topics: Amino Acids; Animals; Arginine; Cell Nucleus; Cysteine; DNA; High Mobility Group Proteins; Histidine; Male; Nucleoproteins; Phosphoproteins; Phosphorylation; Serine; Sheep; Sodium Chloride; Spermatids | 1985 |
Reaction of 5'-p-fluorosulfonylbenzoyl-1,N6-ethenoadenosine with histidine and cysteine residues in the active site of rabbit muscle pyruvate kinase.
Topics: Adenosine; Animals; Binding Sites; Cysteine; Dithiothreitol; Fluorescent Dyes; Histidine; Kinetics; Mathematics; Muscles; Pyruvate Kinase; Rabbits; Tetrazoles | 1985 |
Chemical probes for the active site of aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Animals; Binding Sites; Cysteine; Diethyl Pyrocarbonate; Disulfiram; Histidine; Horses; In Vitro Techniques; Kinetics; Mitochondria, Liver | 1985 |
Localization of the immunity protein-reactive domain in unmodified and chemically modified COOH-terminal peptides of colicin E1.
Topics: Amino Acid Sequence; Bacterial Proteins; Colicins; Cysteine; Histidine; Molecular Weight; Plasmids | 1985 |
Axonal transport of proteins in retinal ganglion cells. Amino acid incorporation into rapidly transported proteins and distribution of radioactivity to the lateral geniculate body and the superior colliculus.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Axonal Transport; Cysteine; Female; Geniculate Bodies; Glycine; Histidine; Leucine; Lysine; Male; Methionine; Nerve Tissue Proteins; Optic Nerve; Phenylalanine; Proline; Rabbits; Retina; Superior Colliculi; Tritium; Tryptophan | 1972 |
Histochemistry of neurosecretion in the pars intercerebralis--corpus cardiacum system of the desert locust Schistocerca gregaria.
Topics: Animals; Azo Compounds; Brain; Cysteine; Cystine; Disulfides; Endoplasmic Reticulum; Epoxy Resins; Grasshoppers; Histidine; Histocytochemistry; Neurosecretion; Neurosecretory Systems; Peptides; RNA; Rosaniline Dyes; Staining and Labeling | 1972 |
Histochemical studies on calcified tissues. I. Amino acid histochemistry of foetal calf and human enamel matrix.
Topics: Amino Acids; Animals; Arginine; Carboxylic Acids; Cattle; Collagen; Cysteine; Dental Enamel; Histidine; Histocytochemistry; Humans; Keratins; Lysine; Microscopy, Phase-Contrast; Odontogenesis; Staining and Labeling; Tooth Germ; Tryptophan; Tyrosine | 1974 |
Histochemical studies on calcified tissues. II. Amino acid histochemistry of developing dentine and bone.
Topics: Amino Acids; Animals; Arginine; Bone Matrix; Calcification, Physiologic; Cattle; Cysteine; Dentin; Dentinogenesis; Histidine; Histocytochemistry; Incisor; Lysine; Odontogenesis; Osteogenesis; Staining and Labeling; Sulfhydryl Compounds; Tooth Germ; Tryptophan; Tyrosine | 1974 |
Reaction of proteins with glutaraldehyde.
Topics: Aldehydes; Animals; Antibodies; Cattle; Chromatography; Cysteine; gamma-Globulins; Histidine; Imidazoles; Immunodiffusion; Immunoelectrophoresis; Ovalbumin; Phenols; Precipitin Tests; Proteins; Serum Albumin; Spectrophotometry; Tyrosine; Ultracentrifugation | 1968 |
The interaction of gamma-globulin with lipids.
Topics: Animals; Arginine; Bence Jones Protein; Benzoates; Cattle; Chickens; Cholesterol; Cysteine; gamma-Globulins; Histidine; Horses; Humans; Hydrogen-Ion Concentration; Iodoacetates; Lysine; Mercury; Methionine; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Binding; Rabbits; Sodium Chloride; Sphingomyelins; Swine; Time Factors; Tyrosine | 1968 |
The designation of the major guinea-pig neural lobe protein as a neurophysin.
Topics: Animals; Antigens; Biological Assay; Cross Reactions; Cysteine; Cystine; Electrophoresis, Polyacrylamide Gel; Glutamine; Glycine; Guinea Pigs; Histidine; Immunodiffusion; Isoleucine; Lysine; Male; Methionine; Molecular Weight; Neurophysins; Pituitary Gland, Posterior; Sulfur Radioisotopes; Tyrosine | 1973 |
A kinetic study of the participation of zinc in human spermatozoa metabolism.
Topics: Calcium; Cysteine; Edetic Acid; Energy Metabolism; Glucose; Histidine; Humans; Kinetics; Magnesium; Male; Oxygen Consumption; Pyruvates; Spectrophotometry, Atomic; Sperm Capacitation; Spermatozoa; Succinates; Time Factors; Zinc | 1973 |
The influence of pH and histidine dipeptides on the production of staphylococcal alpha-toxin.
Topics: Bacterial Proteins; Chromatography, Thin Layer; Culture Media; Cysteine; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Glutathione; Histidine; Histidine Ammonia-Lyase; Hot Temperature; Hydrogen-Ion Concentration; Imidazoles; Mercaptoethanol; Staphylococcus; Toxins, Biological | 1973 |
Regulation of glucosylation of teichoic acid. I. Isolation of phosphoglucomutase in Bacillus subtilis 168.
Topics: Bacillus subtilis; Chelating Agents; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Edetic Acid; Electrophoresis, Disc; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Histidine; Hydroxyapatites; Isoenzymes; Kinetics; Macromolecular Substances; Phosphoglucomutase; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Teichoic Acids; Time Factors | 1974 |
Stereospecific irreversible inhibition of histidine ammonia-lyase by L-cysteine.
Topics: Ammonia-Lyases; Animals; Binding Sites; Binding, Competitive; Carbon Radioisotopes; Cattle; Chromatography, Gel; Cysteine; Dithiothreitol; Edetic Acid; Erythrocytes; Histidine; Histidine Ammonia-Lyase; Homocysteine; Hydrogen-Ion Concentration; Isomerism; Kinetics; Macromolecular Substances; Mercaptoethanol; Oxygen; Protein Binding; Pseudomonas; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfur Radioisotopes; Superoxide Dismutase; Time Factors | 1974 |
Studies on the properties of chemically modified actin. 3. Carbethoxylation.
Topics: Adenosine Triphosphatases; Alkylation; Carbonates; Chemical Phenomena; Chemistry; Cysteine; Histidine; Muscle Proteins; Nucleotides; Optical Rotatory Dispersion; Tyrosine; Viscosity | 1969 |
On the active site of myosin A-adenosine triphosphatase. IX. Chemical modification of the enzyme by monoiodoacetamide.
Topics: Adenosine Triphosphatases; Amides; Animals; Binding Sites; Chloromercuribenzoates; Chromatography; Cysteine; Dextrans; Edetic Acid; Enzyme Activation; Ethylmaleimide; Histidine; Iodoacetates; Lysine; Muscle Proteins; Nitrobenzenes; Rabbits; Sulfonamides; Sulfonic Acids; Toluene; Tyrosine | 1970 |
Supramolecular structure of the rigid layer of the cell wall of Salmonella, Serratia, Proteus, and Pseudomonas fluorescens. Number of lipoprotein molecules in a membrane layer.
Topics: Amino Acids; Arginine; Cell Wall; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; Cytoplasm; Detergents; Disaccharides; Endopeptidases; Escherichia coli; Glycine; Glycosaminoglycans; Histidine; Lipoproteins; Lysine; Membranes; Microscopy, Electron; Molecular Weight; Muramidase; Papain; Peptide Hydrolases; Phenylalanine; Polysaccharides, Bacterial; Proline; Proteus; Pseudomonas; Salmonella typhimurium; Serratia marcescens; Sulfuric Acids; Trypsin | 1970 |
[Histochemical studies of the anal glands in rabbits].
Topics: Animals; Carbohydrates; Cysteine; Female; Glycogen; Glycosaminoglycans; Histidine; Histocytochemistry; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Lipids; Male; Nucleoproteins; Perianal Glands; Rabbits; Succinate Dehydrogenase; Tryptophan; Tyrosine | 1970 |
Effect of inorganic and organic substances containing sulfur or nitrogen and of vitamins on the growth of Mycobacterium leprae.
Topics: Ascorbic Acid; Culture Media; Cysteine; Cystine; Dimethyl Sulfoxide; Folic Acid; Guanosine; Histidine; Mycobacterium leprae; Niacinamide; Nitrates; Nitrites; Nitrogen; Pyridoxal; Sulfur; Thiamine Pyrophosphate; Thiosulfates; Urea; Uric Acid; Vitamins | 1974 |
Pyridoxal and pyridoxamine phosphate breakdown by an acid phosphatase preparation.
Topics: Acid Phosphatase; Acid-Base Equilibrium; Chemical Phenomena; Chemistry; Colorimetry; Cysteine; Edetic Acid; Fluorides; Histidine; Hydrogen-Ion Concentration; Iodoacetates; Magnesium; Mercaptoethanol; Phosphoric Monoester Hydrolases; Pyridoxal Phosphate; Triticum | 1966 |
Transfer ribonucleic acids in Escherichia coli. Multiplicity and variation.
Topics: Amino Acids; Asparagine; Carbon Isotopes; Chemical Phenomena; Chemistry; Chloroquine; Chromatography; Computers; Cysteine; Escherichia coli; Glycine; Histidine; Ligases; Periodic Acid; Proline; RNA, Bacterial; RNA, Transfer; Threonine; Tryptophan | 1968 |
Electron spin resonane of iron-nitric oxide complexes with amino acids, peptides and proteins.
Topics: Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Freezing; Fructose-Bisphosphate Aldolase; Histamine; Histidine; Imidazoles; Insulin; Iron; Iron Isotopes; Methionine; Myoglobin; Nitric Oxide; Nitrogen; Peptides; Proline; Proteins; Radioisotopes; Serum Albumin, Bovine | 1968 |
The fructose 1,6-diphosphatase of Dictyostelium discoideum.
Topics: Adenine Nucleotides; Chemical Phenomena; Chemistry; Cyanides; Cyclic AMP; Cysteine; Edetic Acid; Fructose; Fructose-Bisphosphatase; Hexosephosphates; Histidine; Hydrogen-Ion Concentration; Magnesium; Manganese; Mercaptoethanol; Myxomycetes; Sulfhydryl Compounds | 1969 |
The kinetics of the reactions catalyzed by D-glyceraldehyde-3-phosphate dehydrogenase. 3. The pH dependence of apparent michaelis constants and maximum velocity.
Topics: Animals; Chemical Phenomena; Chemistry; Cysteine; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycerophosphates; Histidine; Hydrogen-Ion Concentration; Kinetics; Mathematics; Muscles; NAD; Swine | 1967 |
Rabbit liver and rabbit kidney fructose diphosphatases: catalytic properties of enzymes activated by coenzyme A and acyl carrier protein.
Topics: Adenine Nucleotides; Animals; Bacterial Proteins; Chelating Agents; Chemical Phenomena; Chemistry; Chlorides; Coenzyme A; Cysteine; Edetic Acid; Enzyme Activation; Escherichia coli; Fatty Acids; Fructose; Fructose-Bisphosphatase; Gluconeogenesis; Glutathione; Glycine; Hexosephosphates; Histidine; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver; Magnesium; Manganese; Nitrogen; Oxidation-Reduction; Protein Binding; Rabbits; Sulfhydryl Compounds | 1970 |
Studies on heart phosphofructokinase. Nature of the enzyme desensitized to allosteric control by photo-oxidation and by acylation with ethoxyformic anhydride.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Amino Acids; Anhydrides; Carbon Isotopes; Centrifugation, Density Gradient; Citrates; Cyclic AMP; Cysteine; Enzyme Activation; Formates; Hexosephosphates; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Methionine; Methylene Blue; Myocardium; Phosphofructokinase-1; Photochemistry; Spectrophotometry | 1970 |
The extracellular nuclease activity of Micrococcus sodonensis. 3. Kinetic studies and control of production.
Topics: Adenine Nucleotides; Carbon Isotopes; Chelating Agents; Chloromercuribenzoates; Cysteine; Cytosine Nucleotides; Edetic Acid; Electrophoresis; Enzyme Activation; Glutathione; Glycine; Histidine; Kinetics; Mercaptoethanol; Micrococcus; Nucleotidases; Organophosphonates; Phosphates; Phosphoric Monoester Hydrolases; Ribonucleases; Uridine | 1970 |
EPR study of Cu(II) complexes of tridentate amino acids.
Topics: Amino Acids; Aminobutyrates; Arginine; Chelating Agents; Chemical Phenomena; Chemistry; Chlorides; Copper; Cysteine; Dicarboxylic Acids; Electron Spin Resonance Spectroscopy; Histidine; Lysine; Methionine; Ornithine; Polyamines; Propionates; Sodium Hydroxide; Time Factors; Tryptophan; Tyrosine | 1971 |
Characterization of porcine malate dehydrogenase. I. An active center peptide.
Topics: Acetamides; Amino Acid Sequence; Animals; Binding Sites; Carbon Isotopes; Carboxypeptidases; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cysteine; Dansyl Compounds; Glycine; Histidine; Iodoacetates; Kinetics; Malate Dehydrogenase; Methionine; Mitochondria, Muscle; Myocardium; NAD; Peptides; Pronase; Serine; Swine; Threonine | 1971 |
Alterations of free amino acids concentrations in cat brain induced by rapid eye movement sleep deprivation.
Topics: Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cats; Caudate Nucleus; Cysteine; Frontal Lobe; Glutamates; Glycine; Hippocampus; Histidine; Lysine; Male; Occipital Lobe; Reticular Formation; Serine; Sleep Deprivation; Sleep, REM; Thalamus; Threonine; Tyrosine | 1971 |
The effect of a paramagnetic center of 2.03 average g-value on d-glyceraldehyde-3-phosphate dehydrogenase.
Topics: Animals; Chromatography, Gel; Cysteine; Dialysis; Electron Spin Resonance Spectroscopy; Glyceraldehyde-3-Phosphate Dehydrogenases; Histidine; Hot Temperature; Hydrogen-Ion Concentration; Iron; Kinetics; Muscles; Nitrous Oxide; Phosphates; Protein Denaturation; Sulfhydryl Compounds; Swine | 1971 |
Reaction of glyceraldehyde-3-phosphate dehydrogenase with dibromoacetone.
Topics: Acetone; Alkylation; Amino Acids; Ammonium Sulfate; Animals; Benzoates; Binding Sites; Borohydrides; Bromine; Carbon Isotopes; Chemical Phenomena; Chemistry; Cysteine; Disulfides; Formates; Glyceraldehyde-3-Phosphate Dehydrogenases; Histidine; Hydrogen-Ion Concentration; Iodoacetates; Kinetics; Mass Spectrometry; Models, Chemical; Muscles; NAD; Nitro Compounds; Oxidation-Reduction; Rabbits | 1972 |
Effects of photooxidation of histidine-38 on the acetylphosphatase activity of glyceraldehyde-3-phosphate dehydrogenase.
Topics: Acetates; Adenosine Diphosphate; Amino Acid Sequence; Animals; Apoproteins; Arsenic; Binding Sites; Catalysis; Cysteine; Drug Stability; Esterases; Glyceraldehyde-3-Phosphate Dehydrogenases; Histidine; Imidazoles; Muscles; NAD; Oxidation-Reduction; Phosphoric Monoester Hydrolases; Photochemistry; Rabbits; Rose Bengal | 1973 |
Functional groups in the catalysis and regulation of Escherichia coli citrate synthase.
Topics: Catalysis; Citrate (si)-Synthase; Citric Acid Cycle; Cysteine; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Methylene Blue; NAD; Oxidation-Reduction; Oxo-Acid-Lyases | 1972 |
Chemotaxis by the nematode Caenorhabditis elegans: identification of attractants and analysis of the response by use of mutants.
Topics: Acetates; Adenosine Monophosphate; Ammonia; Ammonium Chloride; Bromides; Chemotaxis; Chlorides; Cyclic AMP; Cyclic GMP; Cysteine; Histidine; Hydrogen-Ion Concentration; Iodides; Lithium; Lysine; Magnesium; Mutation; Nematoda; Potassium; Sodium | 1973 |
Amino acid sequence of cytochrome c3 from Desulfovibrio vulgaris.
Topics: Amino Acid Sequence; Amino Acids; Apoproteins; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Chymotrypsin; Cysteine; Cytochrome c Group; Desulfovibrio; Heme; Histidine; Peptide Fragments; Peptides; Thiocyanates; Trypsin | 1974 |
Functional groups in the activity and regulation of Escherichia coli citrate synthase.
Topics: Amino Acids; Benzoates; Benzyl Compounds; Binding Sites; Citrate (si)-Synthase; Cysteine; Densitometry; Disulfides; Escherichia coli; Esters; Formates; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Ketoglutaric Acids; Kinetics; Methylene Blue; Molecular Weight; NAD; Nitro Compounds; Nitrobenzenes; Oxidation-Reduction; Oxo-Acid-Lyases; Phenols; Photochemistry; Rose Bengal; Tryptophan | 1973 |
The physical chemistry of hemes and hemopeptides. 3. Synthesis and physicochemical properties of cytochrome c-related heme--pentapeptide soluble in organic solvents.
Topics: Binding Sites; Chromatography, Ion Exchange; Cysteine; Cytochrome c Group; Drug Stability; Electron Spin Resonance Spectroscopy; Glycine; Heme; Hemeproteins; Histidine; Iron; Ligands; Oligopeptides; Optical Rotation; Oxidation-Reduction; Protein Binding; Protein Conformation; Solubility; Spectrophotometry; Spectrophotometry, Ultraviolet | 1974 |
Pyridoxal phosphate-sensitized photoinactivation of glutamate decarboxylase from Clostridium perfringens.
Topics: Amino Acids; Carboxy-Lyases; Chromatography, Ion Exchange; Circular Dichroism; Clostridium perfringens; Cysteine; Glutamates; Histidine; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Oxygen; Photochemistry; Pyridoxal Phosphate; Spectrometry, Fluorescence; Time Factors | 1974 |
Molecular conformation and cooperativity in hemoglobin.
Topics: Binding Sites; Carbon Monoxide; Cyanides; Cysteine; Diphosphoglyceric Acids; Fluoroacetates; Fourier Analysis; Hemoglobins; Histidine; Humans; Hydrogen-Ion Concentration; Iron Isotopes; Ligands; Magnetic Resonance Spectroscopy; Models, Structural; Oxygen; Oxyhemoglobins; Phosphorus Isotopes; Protein Binding; Protein Conformation; Spectrophotometry; Tyrosine | 1973 |
50-S ribosomal proteins. Purification and partial characterization of two acidic proteins, A 1 and A 2, isolated from 50-S ribosomes of Escherichia coli.
Topics: Alanine; Amino Acids; Autoanalysis; Bacterial Proteins; Chromatography, DEAE-Cellulose; Cysteine; Electrophoresis; Escherichia coli; Histidine; Isoelectric Focusing; Molecular Weight; Ribosomes; Sodium Dodecyl Sulfate; Tryptophan; Tyrosine; Ultracentrifugation | 1972 |
Properties of the ribonucleic acid bacteriophage ZIK-1 coat protein and its synthesis in an Escherichia coli cell-free system.
Topics: Amino Acids; Carbon Isotopes; Cell-Free System; Chromosomes; Coliphages; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Methionine; Molecular Weight; Peptide Biosynthesis; RNA Viruses; RNA, Viral; Tritium; Viral Proteins | 1972 |
The role of histidine residues in yeast hexokinase. Enzymic and structural studies.
Topics: Acylation; Allosteric Regulation; Binding Sites; Carbonates; Chromatography, Ion Exchange; Cysteine; Drug Stability; Ethyl Ethers; Glucose; Hexokinase; Histidine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Protein Binding; Protein Conformation; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Ultracentrifugation | 1973 |
Histochemical studies on calcified tissues. 3. Amino acid histochemistry of carious dentine and dentinal reactions to caries.
Topics: Amino Acids; Arginine; Cysteine; Decalcification Technique; Dental Caries; Dentin; Histidine; Histocytochemistry; Humans; Lysine; Tryptophan; Tyrosine | 1974 |
Modification of transfer ribonucleic acid by an alkylating fragment from S-(1,2-dichlorovinyl)-L-cysteine.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Binding Sites; Carbon Radioisotopes; Chromatography, Gel; Cysteine; Escherichia coli; Histidine; Liver; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Species Specificity; Spectrophotometry, Ultraviolet; Sulfur Radioisotopes; Transfer RNA Aminoacylation; Tyrosine; Vinyl Compounds | 1974 |
Ribonucleic acid regulation in amino acid-limited cultures of Escherichia coli grown in a chemostat.
Topics: Amino Acids; Arginine; Bacterial Proteins; Carbon Radioisotopes; Cell Count; Chloramphenicol; Cysteine; Escherichia coli; Galactosidases; Histidine; Methionine; Microscopy, Phase-Contrast; Mutation; Oligonucleotides; Phenylalanine; RNA, Bacterial; Tritium; Uridine | 1974 |
Hyperalimentation in cirrhotic patients.
Topics: Acid-Base Equilibrium; Acidosis; Alanine Transaminase; Alkaline Phosphatase; Amino Acids; Ammonia; Arginine; Carbon Dioxide; Caseins; Catheterization; Cysteine; Diet Therapy; Fibrin; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Liver Cirrhosis; Lysine; Methionine; Parenteral Nutrition; Phenylalanine; Potassium; Sodium; Threonine; Tryptophan | 1972 |
The myoglobin of primates. II. Pan Troglodytes (chimpanzee).
Topics: Amino Acid Sequence; Amino Acids; Animals; Chromatography, Paper; Cysteine; Electrophoresis, Paper; Haplorhini; Histidine; Humans; Hydrolysis; Myoglobin; Pan troglodytes; Species Specificity; Trypsin | 1972 |
Isolation of a cysteine-peptide at the active site of histidine ammonia-lyase.
Topics: Alkylation; Amino Acids; Ammonia-Lyases; Benzoates; Binding Sites; Carbon Isotopes; Chromatography, Gel; Chromatography, Paper; Cysteine; Disulfides; Electrophoresis, Paper; Ethylmaleimide; Histidine; Iodoacetates; Kinetics; Macromolecular Substances; Molecular Weight; Nitro Compounds; Oxidation-Reduction; Peptides; Pseudomonas; Trypsin | 1972 |
The chemical composition of wool. XI. Separation and analysis of exocuticle and endocuticle.
Topics: Amino Acids; Animals; Aspartic Acid; Coloring Agents; Cysteine; Cystine; Formates; Histidine; Leucine; Lysine; Methionine; Microscopy, Electron; Phenylalanine; Proline; Pronase; Sheep; Structure-Activity Relationship; Threonine; Tyrosine; Wool | 1972 |
Application of sequenator analyses to the study of proteins.
Topics: Acetamides; Amino Acid Sequence; Animals; Arginine; Benzyl Compounds; Buffers; Butyrates; Chemical Phenomena; Chemistry; Chromatography, Gas; Cyanogen Bromide; Cysteine; Fluorine; Histidine; Hydroxylamines; Macromolecular Substances; Methods; Methylamines; Proteins; Silicon; Swine; Thermolysin; Thiocyanates; Trypsin | 1972 |
Enhancement of iron absorption from ligated segments of rat intestine by histidine, cysteine, and lysine: effects of removing ionizing groups and of stereoisomerism.
Topics: Alanine; Amino Acids; Animals; Biological Transport, Active; Chelating Agents; Chemical Phenomena; Chemistry; Cysteine; Deamination; Decarboxylation; Duodenum; Histidine; Intestine, Small; Ions; Iron; Iron Isotopes; Ligation; Lysine; Male; Rats; Serine; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds | 1973 |
The effect of bifunctional and monofunctional azo-dye reagents upon the oxygen-binding mechanism of human hemoglobin.
Topics: Acetamides; Alkylation; Autoanalysis; Azo Compounds; Chromatography, Ion Exchange; Cysteine; Hemoglobins; Histidine; Humans; Iodoacetates; Kinetics; Lysine; Macromolecular Substances; Oxygen; Oxygen Consumption; Protein Binding; Protein Conformation; Spectrophotometry; Structure-Activity Relationship; Ultracentrifugation | 1973 |
Quantitative effects of nutritional essential amino acid deficiency upon immune responses to tumors in mice.
Topics: Adenocarcinoma; Amino Acids; Animals; Antibodies, Neoplasm; Antigen-Antibody Complex; Arginine; Cells, Cultured; Cysteine; Cytotoxicity Tests, Immunologic; Deficiency Diseases; Diet; Histidine; Immunity, Cellular; Isoleucine; Lysine; Male; Mammary Neoplasms, Experimental; Methionine; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Phenylalanine; Threonine; Time Factors; Tryptophan; Tyrosine; Valine | 1973 |
On the mode of activation of the catalytically essential sulfhydryl group of papain.
Topics: Acetamides; Acylation; Alkylation; Amides; Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Deuterium; Histidine; Hydrogen-Ion Concentration; Imidazoles; Iodoacetates; Kinetics; Papain; Sulfhydryl Compounds; X-Ray Diffraction | 1973 |
Affinity labeling of aspartate aminotransferase isozymes by bromopyruvate.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Binding Sites; Bromine; Carbon Isotopes; Chemical Phenomena; Chemistry; Circular Dichroism; Cysteine; Cytoplasm; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Lysine; Mitochondria, Muscle; Myocardium; Peptides; Pyruvates; Spectrophotometry, Ultraviolet; Sulfinic Acids; Swine | 1973 |
Analysis of thiohydantoins from amino acids by gas-liquid chromatography on short glass capillary columns.
Topics: Amino Acids; Arginine; Chromatography, Gas; Cysteine; Histidine; Hydantoins; Mass Spectrometry; Methods; Ornithine; Spectrophotometry, Ultraviolet; Temperature; Thiohydantoins | 1973 |
Relative reactivities of nucleophilic centers in some monopeptides.
Topics: Acetamides; Alkylation; Amides; Azirines; Chemical Phenomena; Chemistry; Cysteine; Histidine; Iodoacetates; Methionine; Peptides; Protein Conformation; Structure-Activity Relationship; Tyrosine | 1973 |
[Comparative studies on the influence of radioprotectors and amino acids on the chromosome-damaging activity of 8-hydroxyquinoline sulfate in human lymphocytes in vitro].
Topics: Alanine; Amino Acids; Arginine; Asparagine; beta-Aminoethyl Isothiourea; Cells, Cultured; Chromatids; Chromosome Aberrations; Chromosomes; Cysteamine; Cysteine; Dose-Response Relationship, Drug; Glutamates; Histidine; Humans; Lymphocytes; Methionine; Quinolines | 1973 |
Amelogenins. Purification and partial characterization of proteins from developing bovine dental enamel.
Topics: Amelogenesis; Amino Acids; Animals; Cattle; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Dental Enamel; Dental Enamel Proteins; Dialysis; Electrophoresis, Polyacrylamide Gel; Glutamates; Histidine; Hydrogen-Ion Concentration; Keratins; Methionine; Molar; Molecular Weight; Proline; Sodium Dodecyl Sulfate; Ultracentrifugation | 1973 |
Nutrient media for plant parasitic nematodes. V. Amino acid nutrition of Aphelenchoides rutgersi.
Topics: Alanine; Amino Acids; Aminobutyrates; Culture Media; Cysteine; Cystine; Glutamine; Histidine; Isoleucine; Leucine; Methionine; Mitosporic Fungi; Nematoda; Phenylalanine; Reproduction; Tyrosine | 1973 |
Alterations in sulphur-containing amino acids in rat brain extracts on storage.
Topics: Amino Acids; Animals; Autoanalysis; Brain; Brain Chemistry; Cystathionine; Cysteine; Cystine; Drug Stability; Freezing; Glutathione; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Male; Nerve Tissue Proteins; Oxidation-Reduction; Rats; Time Factors | 1973 |
Bovine pancreatic deoxyribonuclease A. Isolation of cyanogen bromide peptides; complete covalent structure of the polypeptide chain.
Topics: Alkylation; Amino Acids; Animals; Asparagine; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cyanogen Bromide; Cysteine; Deoxyribonucleases; Disulfides; Histidine; Methane; Nitro Compounds; Pancreas; Peptides; Tyrosine | 1973 |
Mechanisms of carboxymethylation of bovine pancreatic nucleases by haloacetates and tosylglycolate.
Topics: Acetates; Alkylation; Animals; Binding Sites; Bromine; Cattle; Chlorine; Chromatography, Gel; Copper; Cysteine; Deoxyribonucleases; Glycolates; Histidine; Imidazoles; Iodoacetates; Kinetics; Osmolar Concentration; Pancreas; Ribonucleases; Structure-Activity Relationship; Sulfhydryl Compounds; Tosyl Compounds | 1973 |
Investigation of the active site of papain with fluorescent probes.
Topics: Aspartic Acid; Binding Sites; Cysteine; Dioxins; Disulfides; Fluorescent Dyes; Histidine; Hydrogen-Ion Concentration; Nitro Compounds; Oxadiazoles; Papain; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1973 |
Oxidation-reduction properties of the 8 alpha-substituted flavins.
Topics: Acetates; Bromine; Chemical Phenomena; Chemistry; Coloring Agents; Cysteine; Electron Transport; Flavins; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Monoamine Oxidase; Oxidation-Reduction; Oxygen; Riboflavin; Spectrophotometry; Spectrophotometry, Ultraviolet; Succinate Dehydrogenase; Sulfites; Sulfonic Acids | 1973 |
Photo-oxidation of lens proteins by sunlight in the presence of fluorescent derivatives of kynurenine, isolated from the human lens.
Topics: Amino Acids; Chromatography, Gel; Color; Crystallins; Cysteine; Fluorescence; Histidine; Humans; Kynurenine; Methionine; Oxidation-Reduction; Peptide Hydrolases; Photochemistry; Spectrum Analysis; Sunlight; Tryptophan; Tyrosine | 1973 |
Automated Edman degradation: the protein sequenator.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Autoanalysis; Chromatography, Gas; Chromatography, Thin Layer; Cysteine; Evaluation Studies as Topic; Filtration; Histidine; Hydrolysis; Isoleucine; Leucine; Mass Spectrometry; Methods; Peptide Fragments; Proteins; Solubility; Thiocyanates | 1973 |
Presence of a single essential histidyl residue in octopine dehydrogenase as shown by photooxidation.
Topics: Amino Acid Oxidoreductases; Amino Acids; Animals; Cysteine; Histidine; Hydrogen-Ion Concentration; Kinetics; Mollusca; Optical Rotatory Dispersion; Oxidation-Reduction; Photochemistry; Rose Bengal; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Sulfhydryl Compounds | 1973 |
The formation of ferritin from apoferritin. Inhibition and metal ion-binding studies.
Topics: Animals; Apoproteins; Binding Sites; Binding, Competitive; Cadmium; Copper; Cysteine; Ferritins; Histidine; Horses; Hydrogen-Ion Concentration; Iron; Kinetics; Manganese; Protein Binding; Terbium; Zinc | 1973 |
Proteins lacking certain amino acids.
Topics: Arginine; Aspartic Acid; Cysteine; Glutamates; Histidine; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Proteins; Tryptophan; Tyrosine; Valine | 1974 |
Effect of concentrations of ammonium molybdate, diammonium hydrogen phosphate, formaldehyde, and minerals in mixture on the synthesis of amino acids.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Chromatography, Paper; Colorimetry; Cysteine; Formaldehyde; Glycine; Histidine; Minerals; Molybdenum; Organophosphorus Compounds; Quaternary Ammonium Compounds; Sterilization; Sunlight; Tyrosine | 1974 |
Specificity of amino acid transport in Trypanosoma equiperdum.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Binding Sites; Biological Transport; Carbon Radioisotopes; Culture Media; Cysteine; Diffusion; Glucose; Glutamates; Histidine; Lysine; Phenylalanine; Stimulation, Chemical; Trypanosoma | 1974 |
Micropolyamide thin-layer chromatography of phenylthiohydantoin amino acids (PTH) at subnanomolar level. A rapid microtechnique for simultaneous multisample identification after automated Edman degradations.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Autoanalysis; Chromatography, Thin Layer; Cysteine; Evaluation Studies as Topic; Histidine; Hydantoins; Isoleucine; Leucine; Microchemistry; Peptides; Thiocyanates; Thiohydantoins; Time Factors; Ultraviolet Rays | 1974 |
Synthesis and antiestrogenic activity of 2,4-bis(bromomethyl)-estrone methyl ether: a bifunctional alkylating steroid.
Topics: Animals; Benzoates; Binding Sites; Biological Assay; Bromine; Carbon Radioisotopes; Castration; Chromatography, Thin Layer; Cysteine; Estranes; Estrogen Antagonists; Estrone; Female; Glucosephosphate Dehydrogenase; Histidine; Magnetic Resonance Spectroscopy; Mercaptoethanol; Methanol; Methyl Ethers; Nitro Compounds; Ovary; Rats; Sulfhydryl Compounds; Tryptophan; Uterus | 1974 |
Relation between phage sensitivity and symbiotic properties of auxotrophic mutants of Rhizobium meliloti.
Topics: Amino Acids; Arginine; Cysteine; Histidine; Lysogeny; Mutagens; Mutation; Nitrosoguanidines; Plants; Rhizobium; Saccharomyces; Symbiosis | 1974 |
Bovine pepsinogen and pepsin. I. Isolation, purification, and some properties of the pepsinogen.
Topics: Abomasum; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis, Disc; Enzyme Precursors; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Molecular Weight; Pepsin A; Proline; Swine; Tryptophan; Ultracentrifugation | 1968 |
Identification of Shigellae on the basis of selective sensitivity.
Topics: Bacteriological Techniques; Coloring Agents; Cysteine; Drug Resistance, Microbial; Enterobacteriaceae; Escherichia; Escherichia coli; Histidine; Klebsiella; Magnesium Sulfate; Methods; Proteus; Rosaniline Dyes; Salmonella paratyphi A; Salmonella typhi; Salmonella typhimurium; Serratia; Shigella; Shigella dysenteriae; Shigella sonnei | 1967 |
Genetic and biochemical studies of enzymatically active subunits of E. coli tryptophan synthetase.
Topics: Binding Sites; Cysteine; Electrophoresis; Escherichia coli; Glycerophosphates; Histidine; Hydro-Lyases; Indoles; Isoenzymes; Lithium; Methionine; Potassium; Quaternary Ammonium Compounds; Serine; Sodium; Tryptophan | 1968 |
Incorporation into polypeptide and charging on transfer ribonucleic acid of the amino acid analog 5',5',5'-trifluoroleucine by leucine auxotrophs of Escherichia coli.
Topics: Carbon Isotopes; Chloramphenicol; Cysteine; Escherichia coli; Histidine; Isoleucine; Leucine; Ligases; Mutation; Peptide Biosynthesis; Phenylalanine; RNA, Bacterial; RNA, Transfer; Time Factors; Tritium; Uracil | 1969 |
Effect of hypermethylation on the functional properties of transfer ribonucleic acid.
Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Cysteine; Escherichia coli; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Methylation; RNA, Bacterial; RNA, Transfer | 1969 |
Remarkable homology about the disulfide bridges of a trypsin-like enzyme from Streptomyces griseus.
Topics: Amino Acid Sequence; Amino Acids; Animals; Autoanalysis; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; Electrophoresis; Endopeptidases; Histidine; Methods; Pepsin A; Peptide Hydrolases; Peptides; Streptomyces; Sulfides; Trypsin | 1969 |
Horse liver alcohol dehydrogenase. The primary structure of the protein chain of the ethanol-active isoenzyme.
Topics: Alcohol Oxidoreductases; Alkylation; Amino Acid Sequence; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chymotrypsin; Cyanides; Cysteine; Ethanol; Histidine; Horses; Iodoacetates; Isoenzymes; Liver; Malates; Methionine; Mutation; Pepsin A; Peptides; Serine; Trypsin | 1970 |
Sugar transport. 3. Purification and properties of a phosphocarrier protein (HPr) of the phosphoenolpyruvate-dependent phosphotransferase system of Escherichia coli.
Topics: Amino Acids; Bacterial Proteins; Carbon Isotopes; Carrier Proteins; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cysteine; Electrophoresis; Electrophoresis, Disc; Escherichia coli; Hexosamines; Histidine; Hot Temperature; Hydrolysis; Imidazoles; Molecular Weight; Phosphoenolpyruvate; Phosphoproteins; Phosphorus Isotopes; Phosphotransferases; Protein Binding; Proteins; Spectrophotometry; Time Factors; Trypsin; Tryptophan; Tyrosine; Ultracentrifugation; Ultraviolet Rays | 1971 |
Uptake of amino acids by actidione-treated yeast cells. I. Specificity of carriers.
Topics: Amino Acids; Arginine; Aspartic Acid; Binding Sites; Biological Transport; Carrier Proteins; Cell Membrane; Cycloheximide; Cysteine; Glutamates; Glycine; Histidine; Kinetics; Leucine; Lysine; Methionine; Proline; Protein Biosynthesis; Saccharomyces; Saccharomyces cerevisiae | 1971 |
Dialysis studies of liver zinc in zinc-deficient and control rats.
Topics: Animals; Buffers; Cysteine; Deficiency Diseases; Dialysis; Diet; Edetic Acid; Glycine; Histidine; Liver; Male; Rats; Zinc; Zinc Isotopes | 1968 |
The effects of copper and other ions on the ribonucleic acid polymerase activity of isolated rat liver nuclei.
Topics: Animals; Beryllium; Cadmium; Calcium; Cell Nucleus; Cobalt; Copper; Cysteine; DNA; Edetic Acid; Histidine; In Vitro Techniques; Lanthanum; Liver; Male; Mercaptoethanol; Mercury; Nucleotidyltransferases; Rats; Selenium; Silver | 1969 |
o-Quinones formed in plant extracts. Their reactions with amino acids and peptides.
Topics: Amino Acids; Catechol Oxidase; Chemical Phenomena; Chemistry; Chlorogenic Acid; Cinnamates; Color; Cysteine; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lysine; Manometry; Nicotiana; Oxygen Consumption; Peptides; Plant Extracts; Plants; Plants, Toxic; Proline; Quinones; Spectrophotometry; Time Factors; Tryptophan | 1969 |
Chemical composition of exosporium from spores of Bacillus cereus.
Topics: Amino Acids; Bacillus cereus; Calcium; Cell Membrane; Chemical Phenomena; Chemistry; Chromatography; Cysteine; Cystine; Fatty Acids; Histidine; Lipids; Methionine; Phospholipids; Phosphorus; Polysaccharides; Proteins; Spores; Tyrosine | 1970 |
Delayed lysis in Salmonella phage P22: the appearance of free fatty acids coincident with induced cell lysis.
Topics: Acetates; Bacteriolysis; Carbon Isotopes; Chromatography, Thin Layer; Colorimetry; Cyanides; Cysteine; Edetic Acid; Fatty Acids, Essential; Histidine; Lipase; Lipids; Lysogeny; Mutation; Palmitic Acids; Salmonella Phages; Salmonella typhimurium; Vibration | 1970 |
-Bromo- -(5-imidazolyl)propionic acid and its reaction with cysteine.
Topics: Alanine; Amino Acids; Autoanalysis; Bromine; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; Drug Stability; Histidine; Hydrogen-Ion Concentration; Imidazoles; Indicators and Reagents; Kinetics; Propionates; Stereoisomerism | 1972 |
Multiple effects of anions on ATP:L-arginine phosphotransferases.
Topics: Adenosine Triphosphate; Animals; Arginine; Bivalvia; Chlorine; Cysteine; Histidine; Invertebrates; Ions; Kinetics; Magnesium; Muscles; Nephropidae; Optical Rotatory Dispersion; Osmolar Concentration; Phosphotransferases; Protein Binding; Spectrophotometry; Structure-Activity Relationship; Temperature; Time Factors; Ultracentrifugation; Ultraviolet Rays | 1972 |
Synthesis of 21-acryloxyprogesterone, 21-bromoacetoxyprogesterone and 11 -bromacetoxyprogesterone for affinity labeling.
Topics: Acetates; Acrylates; Bromine; Chemical Phenomena; Chemistry; Chlorine; Chromatography, Thin Layer; Cyclohexanes; Cysteine; Dimethylformamide; Esters; Histidine; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Imines; Mercaptoethanol; Methionine; Streptomyces | 1972 |
Stability constant for the zinc-dithiothreitol complex.
Topics: Animals; Chelating Agents; Cysteine; Dithiothreitol; Drug Stability; Enzyme Activation; Histidine; Liver; Lyases; Mercaptoethanol; Methods; Rats; Zinc | 1972 |
Partial resolution of the enzymes catalyzing photophosphorylation. X. Purification of spinach cytochrome f and its photooxidation by resolved photosystem I particles.
Topics: Amino Acids; Ascorbic Acid; Chlorophyll; Chloroplasts; Chromatography, Gel; Chromatography, Ion Exchange; Copper; Cysteine; Cytochromes; Electrophoresis; Histidine; Kinetics; Light; Macromolecular Substances; Molecular Weight; Oxidation-Reduction; Photophosphorylation; Photosynthesis; Plant Proteins; Plants; Radiation Effects; Solubility; Spectrophotometry | 1972 |
Competition for zinc among serum albumin and amino acids.
Topics: Amino Acids; Chromatography, Gel; Cysteine; Histidine; Humans; Mathematics; Models, Chemical; Potentiometry; Protein Binding; Serum Albumin; Zinc | 1972 |
Photooxidation of formyltetrahydrofolate synthetase in the presence of methylene blue.
Topics: Adenosine Triphosphate; Amino Acids; Binding Sites; Catalysis; Clostridium; Cysteine; Formates; Histidine; Hydrogen-Ion Concentration; Kinetics; Ligases; Light; Methionine; Methylene Blue; Photochemistry; Protein Binding; Radiation Effects; Tetrahydrofolates | 1972 |
Chemical modification of the high-affinity bilirubin-binding site of human-serum albumin.
Topics: Acylation; Arginine; Aspirin; Bilirubin; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Gel; Cysteine; Electrophoresis; Histidine; Humans; Lysine; Protein Binding; Protein Conformation; Serum Albumin; Tryptophan; Tyrosine | 1972 |
Potential production and detoxification of penicillic acid in mold-fermented sausage (salami).
Topics: Alkylation; Animals; Arginine; Birds; Caproates; Chick Embryo; Culture Media; Cysteine; Female; Fermentation; Food Contamination; Food Microbiology; Glutathione; Histidine; Lysine; Male; Meat; Mice; Mice, Inbred Strains; Mycotoxins; Penicillium; Rabbits; Skin Tests; Time Factors | 1972 |
Selective free radical reactions with proteins and enzymes: reactions of inorganic radical anions with amino acids.
Topics: Alanine; Amino Acids; Bromides; Carbonates; Chlorides; Cysteine; Free Radicals; Histidine; Hydrogen-Ion Concentration; Iodides; Kinetics; Methionine; Muramidase; Proteins; Radiation Effects; Radiochemistry; Spectrophotometry; Thiocyanates; Tryptophan; Tyrosine | 1972 |
The labelling of proteins by irradiation in tritiated water.
Topics: Alkylation; Amino Acids; Animals; Cetacea; Chromatography, Ion Exchange; Cysteine; Egg White; Endopeptidases; Histidine; Isotope Labeling; Leucyl Aminopeptidase; Muramidase; Myoglobin; Phenylalanine; Photolysis; Pronase; Radiation Effects; Tritium; Tryptophan; Tyrosine; Ultraviolet Rays; Water; Wool | 1972 |
New protein reagents. I. Ethyl chloroacetimidate, its properties and its reaction with ribonuclease.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Chlorine; Chromatography, Thin Layer; Cysteine; Esters; Glycine; Histidine; Hydrolysis; Imidoesters; Imines; Indicators and Reagents; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Pancreas; Ribonucleases; Sulfhydryl Compounds | 1972 |
[Histochemical studies on female genital organs during fetal development. V. Protein histochemistry of the human ovary].
Topics: Amino Acids; Cysteine; Cystine; Embryo, Mammalian; Epithelial Cells; Epithelium; Female; Fetus; Gestational Age; Histidine; Histocytochemistry; Humans; Hydroxylysine; Infant, Newborn; Lysine; Ovarian Follicle; Ovary; Pregnancy; Proteins; Tryptophan | 1972 |
[Histochemical studies on female genital organs during fetal development. VI. Protein histochemistry of the uterine tubes].
Topics: Arginine; Cysteine; Cystine; Epithelial Cells; Epithelium; Fallopian Tubes; Female; Fetus; Gestational Age; Histidine; Histocytochemistry; Humans; Hydroxylysine; Lysine; Pregnancy; Proteins; Tryptophan; Tyrosine | 1972 |
Reactivities of the various protonic states in the reactions of papain and of L-cysteine with 2,2'- and with 4,4'- dipyridyl disulphide: evidence for nucleophilic reactivity in the un-ionized thiol group of the cysteine-25 residue of papain occasioned by
Topics: Asparagine; Cysteine; Disulfides; Histidine; Hydrogen-Ion Concentration; Papain; Pyridines; Sulfhydryl Compounds | 1972 |
Kinetics of the reversible reaction of papain with 5,5'-dithiobis-(2-nitrobenzoate) dianion: evidence for nucleophilic reactivity in the un-ionized thiol group of cysteine-25 and for general acid catalysis by histidine-159 of the reaction of the 5-mercapt
Topics: Benzoates; Catalysis; Cysteine; Disulfides; Histidine; Kinetics; Nitro Compounds; Papain; Sulfhydryl Compounds; Sulfides | 1972 |
[Differentiation of two cathepsins from cod muscle].
Topics: Animals; Cathepsins; Chemical Phenomena; Chemistry; Cysteine; Fishes; Histidine; Imidazoles; Muscles; Oxidation-Reduction; Peptide Hydrolases; Serine | 1971 |
Ligand exchange amino acid analysis: resolution of some amino sugars and cysteine derivatives.
Topics: Acetates; Amino Acids; Arginine; Autoanalysis; Buffers; Cysteine; Galactose; Glucosamine; Hexosamines; Histidine; Hydrogen-Ion Concentration; Ion Exchange Resins; Mannose; Methods; Ovalbumin; Phenylalanine; Sodium; Tyrosine; Zinc | 1971 |
The characterization of chemically modified hemoglobins. 3. Reaction with various N-substituted maleimides.
Topics: Alkylation; Amino Acid Sequence; Animals; Bromine; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis; Esters; Ethers; Hemoglobins; Histidine; Horses; Hydrolysis; Oxygen; Pyrroles; Valine | 1971 |
Chemical modification of the active site of yeast invertase.
Topics: Acetamides; Alkylation; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Cyanogen Bromide; Cysteine; Dialysis; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Iodides; Iodine; Iodoacetates; Iodoproteins; Kinetics; Mercaptoethanol; Mercaptoethylamines; Mercury; Methane; Methionine; Models, Chemical; Models, Structural; Nitrates; Nitro Compounds; Organometallic Compounds; Saccharomyces; Spectrophotometry; Sucrase; Tyrosine | 1971 |
[Histochemical studies of female genitalia during fetal development. IV. Protein histochemistry of the uterus].
Topics: Alloxan; Amino Acids; Arginine; Cervix Uteri; Cysteine; Cystine; Cytoplasm; Female; Fetus; Gestational Age; Histidine; Histocytochemistry; Humans; Hydroxylysine; Imidazoles; Lysine; Nitrobenzenes; Proteins; Schiff Bases; Sulfhydryl Compounds; Tetrazolium Salts; Tryptophan; Tyrosine; Uterus | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
[Dissociation of S- and P-variants of Bacillus brevis var. G.-B. on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Mutation; Nitrogen; Ornithine; Phenylalanine; Serine; Stimulation, Chemical; Threonine; Time Factors; Tryptophan; Valine | 1971 |
A sulfhydryl reagent containing an imidazole ring: D,L-alpha-bromo-beta-(5-imidazolyl)-propionic acid.
Topics: Bromine; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; Histidine; Imidazoles; Papain; Propionates; Stereoisomerism; Sulfhydryl Reagents; Sulfides | 1971 |
Organ-specific inhibition of human alkaline phosphatase isoenzymes of liver, bone, intestine and placenta; L-phenylalanine, L-tryptophan and L homoarginine.
Topics: Alkaline Phosphatase; Amino Acids; Bile Acids and Salts; Bone and Bones; Cysteine; Dihydroxyphenylalanine; Guanidines; Histidine; Humans; Intestines; Isoenzymes; Liver; Organ Specificity; Phenylalanine; Phosphoric Acids; Placenta; Stereoisomerism; Structure-Activity Relationship; Tryptophan; Tyrosine | 1971 |
Studies on the partial exchange and overall reactions catalyzed by native and modified arginine kinase from Homarus vulgaris muscle.
Topics: Adenine Nucleotides; Alkylation; Animals; Annelida; Arginine; Binding Sites; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Paper; Creatine Kinase; Cysteine; Dansyl Compounds; Guanosine Triphosphate; Histidine; Kinetics; L-Lactate Dehydrogenase; Lysine; Muscles; Nephropidae; Phosphotransferases; Protein Binding; Pyruvate Kinase; Rabbits | 1971 |
Group separation: a new method facilitating isolation of peptides from digests of high molecular weight proteins.
Topics: Anhydrides; Arginine; Carboxypeptidases; Chromatography, Ion Exchange; Chymotrypsin; Cysteine; Endopeptidases; Histidine; Imides; Lysine; Maleates; Methionine; Methods; Peptides; Phosphoproteins; Proteins; Serine; Trypsin | 1971 |
Studies on leukocyte phosphatases. 3. Inhibition of leukocyte acid phosphatase by zinc.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Cattle; Cysteine; Enzyme Activation; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Leukocytes; Serum Albumin, Bovine; Spectrophotometry; Zinc | 1971 |
Studies on the reaction of chloromethane with human blood.
Topics: Autoanalysis; Blood Proteins; Carbon Isotopes; Catalysis; Chromatography, Thin Layer; Cysteine; Erythrocytes; Glutathione; Histidine; Humans; Hydrolysis; Methyl Chloride; Oxygen Consumption; Protein Binding; Serum Albumin | 1971 |
Comparison of invariant residues in the variable and constant regions of human K, human L, and mouse K Bence-Jones proteins.
Topics: Amino Acid Sequence; Animals; Bence Jones Protein; Cysteine; Glutamates; Histidine; Humans; In Vitro Techniques; Leucine; Lysine; Mice; Phenylalanine; Proline; Serine; Tryptophan; Valine | 1967 |
Amino acid fermentation by Fusobacterium nucleatum.
Topics: Amino Acids; Aspartic Acid; Cysteine; Fermentation; Fusobacterium; Gingiva; Glutamates; Glutamine; Histidine; Humans; Lysine; Methionine; Mouth; Serine; Threonine | 1968 |
The nature of general base-general acid catalysis in serine proteases.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Deuterium; Endopeptidases; Histidine; Kinetics; Models, Chemical; Models, Structural; Serine | 1969 |
Haemoglobin Rainier: beta-145 (HC2) tyrosine leads to cysteine and haemoglobin Bethesda: beta-145 (HC2) tyrosine leads to histidine.
Topics: Amino Acid Sequence; Blood Protein Electrophoresis; Carboxypeptidases; Chromatography, Paper; Cysteine; Hemoglobins, Abnormal; Histidine; Humans; Peptides; Trypsin; Tyrosine | 1971 |
Probing the topography of proteins in solution by photosensitized oxidation. The catalytic region of papain.
Topics: Amino Acids; Binding Sites; Chromatography; Circular Dichroism; Cysteine; Dinitrophenols; Fluoresceins; Fluorescence; Histidine; Light; Oxidation-Reduction; Papain; Spectrophotometry; Thiocarbamates; Tryptophan | 1971 |
Amino acid requirements in vitro of human leukemic cells.
Topics: Amino Acids; Asparaginase; Asparagine; Cells, Cultured; Culture Media; Cysteine; Female; Glutamine; Histidine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Tritium; Tyrosine; Uridine | 1971 |
Chemistry of gonadotrophins in relation to their antigenic properties.
Topics: Amino Acids; Antigens; Chorionic Gonadotropin; Complement Fixation Tests; Cysteine; Follicle Stimulating Hormone; Gonadotropins; Histidine; Humans; Immune Sera; Luteinizing Hormone; Methionine; Neuraminic Acids; Prolactin; Radioimmunoassay; Tryptophan; Tyrosine | 1969 |
Studies on polynucleotides. LVI. Further syntheses, in vitro of copolypeptides containing two amino acids in alternating sequence dependent upon DNA-like polymers containing two nucleotides in alternating sequence.
Topics: Amino Acids; Arginine; Chromatography, Paper; Cysteine; Dinitrophenols; Escherichia coli; Genetic Code; Glutamates; Histidine; In Vitro Techniques; Kinetics; Peptide Biosynthesis; Polynucleotides; Ribosomes; Thiocyanates; Threonine; Trypsin; Valine | 1966 |
Studies on polynucleotides. LXXIV. Direct translation in vitro of single-stranded DNA-like polymers with repeating nucleotide sequences in the presence of neomycin B.
Topics: Alanine; Carbon Isotopes; Chromatography, Paper; Cysteine; DNA, Bacterial; Escherichia coli; Genetic Code; Histidine; Methionine; Neomycin; Peptide Biosynthesis; Polynucleotides; Ribosomes; RNA, Transfer; Thiocyanates; Threonine; Valine | 1967 |
[Methods for activating amino acids in tissues of the animal organism].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Amino Acids; Animals; Cysteine; Fluorides; Glycine; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; Leucine; Ligases; Lysine; Magnesium; Manganese; Methods; Microsomes, Liver; Oxygen Isotopes; Phosphates; Pyrophosphatases; Rats; Spectrum Analysis | 1969 |
Dye-sensitized selective photo-oxidation of cysteine.
Topics: Acetates; Amino Acids; Chromatography, Gel; Chromatography, Paper; Chromatography, Thin Layer; Coloring Agents; Cresols; Cysteine; Cystine; Egg White; Gentian Violet; Glutathione; Guanidines; Histidine; Hydrochloric Acid; Hydrogen-Ion Concentration; Kinetics; Light; Mercaptoethanol; Methionine; Muramidase; Optical Rotation; Oxidation-Reduction; Peptides; Radiation Effects; Spectrophotometry; Structure-Activity Relationship; Sulfonic Acids; Tryptophan; Tyrosine; Ultraviolet Rays | 1969 |
The mechanism of transamination. Function of the histidyl residue at the active site of supernatant aspartate transaminase.
Topics: Aspartate Aminotransferases; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Coenzymes; Cysteine; Dicarboxylic Acids; Glutarates; Histidine; Ketoglutaric Acids; Kinetics; Light; Models, Biological; Models, Chemical; Oxidation-Reduction; Pyridoxal Phosphate; Pyridoxine; Radiation Effects; Spectrophotometry; Spectrum Analysis; Sulfinic Acids; Tritium; Ultraviolet Rays | 1970 |
Amino acid sequence studies on rabbit skeletal muscle actin. Cyanogen bromide cleavage of the protein and determination of the sequences of seven of the resulting peptides.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Aminopeptidases; Animals; Autoanalysis; Carboxypeptidases; Cellulose; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cyanides; Cysteine; Endopeptidases; Histidine; Methods; Molecular Weight; Muscle Proteins; Peptides; Rabbits; Trypsin; Tryptophan | 1970 |
The amino acid sequence around the active-site cysteine and histidine residues, and the buried cysteine residue in ficin.
Topics: Acetone; Amino Acid Sequence; Binding Sites; Carbon Isotopes; Chromatography; Chymotrypsin; Cysteine; Histidine; Methylcellulose; Papain; Peptide Hydrolases; Protease Inhibitors; Rubber; Trypsin | 1970 |
The amino acid sequence around the active-site cysteine and histidine residues of stem bromelain.
Topics: Amino Acid Sequence; Bromelains; Carbon Isotopes; Chymotrypsin; Cysteine; Histidine; Iodoacetates; Papain; Peptide Hydrolases; Plants, Edible; Trypsin | 1970 |
Effects of omega-amino acids and related compounds on staphylococcal infections in mice: a combined prophylactic-therapeutic procedure.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminocaproates; Animals; Culture Media; Cyclohexanecarboxylic Acids; Cysteine; Dipeptides; Female; Glycine; Histidine; Hydroxybutyrates; Injections, Subcutaneous; Mice; Staphylococcal Infections; Staphylococcus; Sulfinic Acids; Taurine; Valerates | 1970 |
Purity of amino acids.
Topics: Amino Acids; Arginine; Biological Assay; Cysteine; Histidine; Lysine; Methionine; Pediococcus; Streptococcus; Threonine; Tryptophan; Tyrosine | 1970 |
Reversible polymerization of histidine ammonia lyase. The role of sulfhydryl groups in the activity and polymeric state of the enzyme.
Topics: Ammonia; Boron Compounds; Chemical Phenomena; Chemistry; Chromatography, Gel; Cysteine; Electrophoresis, Disc; Histidine; Lyases; Mercaptoethanol; Molecular Weight; Pseudomonas; Spectrophotometry; Spectrum Analysis; Sulfhydryl Compounds; Ultracentrifugation | 1970 |
A reinvestigation of residues 64-68 and 175 in papain. Evidence that residues 64 and 175 are asparagine.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Chromatography, Gel; Chymotrypsin; Cysteine; Histidine; Imidazoles; Papain; Protein Binding | 1970 |
Synthesis of 2-diazoestrone sulfate and use for affinity labeling of steroid binding sites.
Topics: Alcohols; Benzoates; Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Estradiol; Estrogens; Estrone; Glutamate Dehydrogenase; Glutathione; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Ovalbumin; Spectrophotometry; Steroids; Tryptophan | 1970 |
[Biosynthesis of gramicidin C on synthetic media with amino acids as the only N source].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Tyrothricin; Valine | 1970 |
[Chorismate mutase from Claviceps. II. Activation and inhibition by analogues of the effectors tryptophan, phenylalanine and tyrosine].
Topics: Ascomycota; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Cyclohexanecarboxylic Acids; Cysteine; Enzyme Activation; Histidine; Kinetics; Phenylalanine; Phosphotransferases; Tryptophan; Tyrosine | 1970 |
Reaction of polycyclic hydrocarbon-cysteine conjugates with the aminoacyl-RNA synthetase system.
Topics: Benz(a)Anthracenes; Cysteine; Glutamates; Histidine; In Vitro Techniques; Leucine; Ligases; Methionine; Models, Chemical; Phenanthrenes; Phenylalanine; Protein Binding; RNA, Transfer; Saccharomyces | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
The middle ultraviolet spectra of proteins. I. Studies on model compounds.
Topics: Amino Acids; Benzene; Cresols; Cysteine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Indoles; Methionine; Phenols; Phenylalanine; Proteins; Spectrophotometry; Spectrum Analysis; Toluene; Tryptophan; Tyrosine; Ultraviolet Rays | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
Chemical evidence for chain heterogeneity in rabbit muscle tropomyosin.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; Histidine; Iodoacetates; Methionine; Molecular Weight; Muscle Proteins; Peptides; Rabbits; Trypsin | 1970 |
Effect of Tween 80 on alkaloid-producing cultures of Claviceps paspali.
Topics: Acids; Alanine; Amino Acids; Ascomycota; Chromatography, Paper; Citrates; Colorimetry; Culture Media; Cysteine; Ergot Alkaloids; Fumarates; Histidine; Methionine; Oxaloacetates; Spectrophotometry; Succinates; Surface-Active Agents | 1971 |
Structure of 2-keto-3-deoxy-6-phosphogluconate aldolase. II. Chemical evidence for a three-subunit molecule.
Topics: Aldehyde-Lyases; Alkylation; Amino Acids; Asparagine; Boron Compounds; Carbon Isotopes; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; Detergents; Electrophoresis, Disc; Gluconates; Histidine; Iodoacetates; Molecular Weight; Oxidation-Reduction; Peptides; Pseudomonas; Pyruvates; Sulfuric Acids; Trypsin | 1971 |
[Dissociation of R- and P plus-variants of Bacillus brevis var. G.-B. during growth on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Valine | 1971 |
On the probable involvement of a histidine residue in the active site of pancreatic lipase.
Topics: Acylation; Amino Acids; Animals; Binding Sites; Butyrates; Chemical Phenomena; Chemistry; Chromatography, Gel; Cysteine; Emulsions; Histidine; Hydrogen-Ion Concentration; Kinetics; Light; Lipase; Mercury; Methionine; Methylene Blue; Oxidation-Reduction; Pancreas; Photochemistry; Radiation Effects; Swine; Triglycerides; Tryptophan | 1971 |
Essential histidyl residues of octopine dehydrogenase.
Topics: Animals; Carbonates; Cysteine; Deuterium; Dicarboxylic Acids; Guanidines; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; L-Lactate Dehydrogenase; Mollusca; Muscles; Oxidoreductases; Spectrophotometry; Tyrosine | 1971 |
Purification and characterization of cytochrome 553 from the chrysophycean alga Monochrysis lutheri.
Topics: Amino Acids; Arginine; Autoanalysis; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Cytochromes; Dialysis; Electron Transport; Electrophoresis, Disc; Eukaryota; Freeze Drying; Heme; Histidine; Iron; Isoelectric Focusing; Methionine; Methods; Molecular Weight; Oxidation-Reduction; Photosynthesis; Proline; Quaternary Ammonium Compounds; Spectrophotometry; Sulfates; Tryptophan; Ultracentrifugation; Ultraviolet Rays | 1971 |
[Free amino acids and other ninhydrin-positive substances in the normal horny layer and in psoriasis scales].
Topics: Alanine; Amino Acids; Ammonia; Asparagine; Chromatography; Citrulline; Cysteine; Glycine; Histidine; Humans; Imidazoles; Phenylalanine; Proline; Psoriasis; Serine; Skin; Taurine; Threonine; Urea | 1967 |
[Biosphere products of Sinapis alba. I. Rhizosphere products].
Topics: Alanine; Amino Acids; Aminobutyrates; Arabinose; Arginine; Aspartic Acid; Citrates; Cysteine; Glucose; Glutamates; Glycine; Hexoses; Histidine; Keto Acids; Leucine; Mannose; Mustard Plant; Oxalates; Pentoses; Plants, Medicinal; Proline; Ribose; Threonine; Valine; Xylose | 1967 |
Correlation between spectral changes and synergistic inhibition of bacterial phosphopyruvate hydratase in the presence of two metal ions.
Topics: Brevibacterium; Cysteine; Depression, Chemical; Drug Synergism; Histidine; Hydro-Lyases; Magnesium; Phosphopyruvate Hydratase; Spectrum Analysis; Tryptophan; Ultraviolet Rays; Zinc | 1967 |
[Thin-layer chromatography of amino acids and amines in feces].
Topics: Amines; Amino Acids; Arginine; Chromatography, Thin Layer; Cysteine; Feces; Histidine; Humans; Methods; Taurine | 1967 |
[Quantitative paper chromatography amino acid determination. Stanardization of the procedure and method of testing of new paper types].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glutamates; Glycine; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Methods; Paper; Phenylalanine; Serine; Spectrum Analysis; Sulfones; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1967 |
The active centre of aminopeptidase B. I. The effects of various chemical reagents.
Topics: Aminopeptidases; Animals; Benzene; Binding Sites; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Chymotrypsin; Cysteine; Glucose; Histidine; Imidazoles; Light; Mercury; Methylene Blue; Oxidation-Reduction; Rats; Sulfhydryl Compounds | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Biosynthesis of ergothioneine from endogenous hercynine in Mycobacterium smegmatis.
Topics: Betaine; Chromatography; Chromatography, Paper; Culture Media; Cysteine; Ergothioneine; Histidine; Mycobacterium; Sulfur | 1968 |
Inhibition of heat-induced denaturation of serum proteins by mixtures of nonsteroidal anti-inflammatory agents and amino acids.
Topics: Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Depression, Chemical; Flufenamic Acid; Fluorine; Histamine; Histidine; Hot Temperature; Indomethacin; ortho-Aminobenzoates; Phenylalanine; Phenylbutazone; Protein Denaturation; Serine; Serum Albumin, Bovine; Solutions; Tryptophan; Tyrosine | 1968 |
On the protection of ribulose diphosphate carboxylase from iodoacetamide inhibition.
Topics: Amides; Amino Acids; Carbamates; Carbon Isotopes; Chloroplasts; Chromatography; Cysteine; Histidine; Ligases; Pentosephosphates; Phosphates; Time Factors | 1968 |
Evidence for histidine in the active site of papain.
Topics: Acetone; Alkylation; Amino Acids; Binding Sites; Bromine; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Cysteine; Histidine; Imidazoles; Models, Chemical; Molecular Weight; Optical Rotatory Dispersion; Papain; Plants; Sulfhydryl Compounds | 1968 |
The location of the active-site histidine residue in the primary sequence of papain.
Topics: Acetone; Amino Acid Sequence; Binding Sites; Bromine; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chymotrypsin; Cysteine; Histidine; Methylation; Papain; Peptides; Plants; Protein Hydrolysates; Trypsin | 1968 |
Primary structure of insoluble tendon collagen. 3. Analysis of products of tryptic digestion of native collagen.
Topics: Achilles Tendon; Alanine; Aldehydes; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Electrophoresis; Glutamine; Glycine; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Proline; Serine; Sulfur; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Trace metal requirements for malformin biosynthesis.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Aspergillus; Chromium; Cobalt; Copper; Cysteine; Glutamine; Glycine; Histidine; Iron; Isoleucine; Leucine; Lysine; Manganese; Metals; Molybdenum; Peptide Biosynthesis; Phenylalanine; Plant Growth Regulators; Proline; Serine; Trace Elements; Tryptophan; Tyrosine; Valine; Zinc | 1968 |
Purification and properties of rat liver histidase.
Topics: Animals; Chemical Phenomena; Chemistry; Cysteine; Dialysis; Folic Acid; Glutathione; Histidine; Hydrogen-Ion Concentration; Kinetics; Liver; Lyases; Mercaptoethanol; Metals; Molecular Weight; Rats | 1968 |
[Photolysis of amino acids].
Topics: Amino Acids; Cysteine; Heterocyclic Compounds; Histidine; Hydrogen-Ion Concentration; Infrared Rays; Methionine; Radiation Effects; Sulfur; Ultraviolet Rays | 1968 |
[On the influence of the starting position on migration of substances in paper electrophoresis].
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Asparagine; Cysteine; Electrophoresis; Glucose; Glutamates; Glutamine; Glycine; Histidine; Leucine; Lysine; Methionine; Serine; Serum Albumin; Taurine; Tryptophan | 1968 |
Evidence for histidine in the active sites of ficin and stem-bromelain.
Topics: Acetone; Alkylation; Bromelains; Bromine; Chemical Phenomena; Chemistry; Chromatography, Gel; Cysteine; Endopeptidases; Histidine; Protease Inhibitors | 1968 |
[Physical and chemical properties of goose hemoglobin].
Topics: Amino Acids; Animals; Biological Evolution; Blood Proteins; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; Electrophoresis; Geese; Hemoglobins; Histidine; Methylcellulose; Peptides | 1968 |
Amino acid analysis and peptide mapping of bovine carotid actin.
Topics: Amino Acids; Animals; Carotid Arteries; Cattle; Cysteine; Electrophoresis; Histidine; Molecular Weight; Muscle Proteins; Peptides; Rabbits; Trypsin; Ultracentrifugation | 1969 |
Structural studies on rabbit muscle glycerol 3-phosphate dehydrogenase and a comparison of chemical and physical determinations of its molecular weight.
Topics: Alkylation; Amino Acids; Animals; Arginine; Autoradiography; Bees; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Gel; Chymotrypsin; Cysteine; Glycerolphosphate Dehydrogenase; Histidine; Isomerases; Kinetics; Lysine; Molecular Weight; Muscles; Rabbits; Rats; Species Specificity; Trypsin; Tryptophan; Tyrosine; Ultracentrifugation | 1969 |
The specificity of purified porcine pancreatic elastase.
Topics: Alanine; Animals; Chromatography; Cysteine; Electrophoresis; Glutamates; Glycine; Histidine; Insulin; Leucine; Pancreas; Pancreatic Elastase; Phenylalanine; Serine; Swine; Valine | 1969 |
The reaction of iodoacetamide with the active center of gamma-glutamyl transpeptidase.
Topics: Alkylation; Amides; Animals; Autoradiography; Borates; Catalysis; Cattle; Cysteine; Electrophoresis; Enzymes; Glycolates; Histidine; In Vitro Techniques; Kidney; Lysine; Methionine; Molecular Weight; Serine; Transferases | 1965 |
The effect of ultraviolet light and thiol compounds on guinea pig skin histidase.
Topics: Animals; Cysteine; Glutathione Reductase; Guinea Pigs; Histidine; In Vitro Techniques; Lyases; Skin; Sulfhydryl Compounds; Ultraviolet Rays | 1966 |
Phosphoglucomutase. 3. Purification and properties of phosphoglucomutases from flounder and shark muscle.
Topics: Animals; Chemical Phenomena; Chemistry; Cysteine; Fishes; Hexosephosphates; Histidine; Imidazoles; In Vitro Techniques; Kinetics; Magnesium; Muscles; Phosphoglucomutase; Sharks | 1966 |
Effect of dietary synthetic and natural chelating agents on the zinc-deficiency syndrome in the chick.
Topics: Animals; Chelating Agents; Cysteine; Cystine; Deficiency Diseases; Dietary Proteins; Hearing Loss, Noise-Induced; Histidine; Poultry; Zinc | 1966 |
[Two dimension chromatography of ether soluble dinitrophenyl-amino acids and chromato-electrophoresis of hydracid-soluble DNP-amino acids on thin layers of powdered cellulose].
Topics: Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography, Thin Layer; Cysteine; Dinitrophenols; Electrophoresis; Glutamates; Glutamine; Histidine; Lysine | 1966 |
Genetic control of the uptake of amino acids in Neurospora.
Topics: Amino Acids; Arginine; Cysteine; Enzyme Repression; Enzymes; Genes; Histidine; Leucine; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Tryptophan; Tyrosine; Valine | 1966 |
[The "reequilibration" test and its use in the treatment of certain forms of cancer and other afflictions].
Topics: Adenosine Triphosphate; Asparagine; Betaine; Choline; Creatine; Cysteine; Deficiency Diseases; Electrophoresis; Elements; Glutamates; Histidine; Humans; Metabolic Diseases; Methionine; Neoplasms; Quaternary Ammonium Compounds | 1966 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
The influence of nitrogenous compounds on growth of Pythium species.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Cysteine; Fungi; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Nitrates; Nitrites; Nitrogen; Peptones; Quaternary Ammonium Compounds; Serine; Succinates; Threonine; Yeast, Dried | 1967 |
Thiolysis of some dinitrophenyl derivatives of amino acids.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Dinitrophenols; Histidine; Mercaptoethanol; Spectrophotometry; Sulfhydryl Compounds; Tyrosine | 1967 |
Primary structure of tyrosinase from Neurospora crassa. II. Complete amino acid sequence and chemical structure of a tripeptide containing an unusual thioether.
Topics: Amino Acid Sequence; Catechol Oxidase; Cysteine; Ethers; Histidine; Monophenol Monooxygenase; Neurospora; Neurospora crassa; Oligopeptides; Spectrophotometry, Ultraviolet | 1982 |
Identification of histidyl and cysteinyl residues essential for catalysis by 5'-nucleotidase.
Topics: 5'-Nucleotidase; Animals; Binding Sites; Catalysis; Cell Membrane; Cysteine; Cytosol; Histidine; Liver; Nucleotidases; Rats; Sulfhydryl Reagents | 1984 |
Mutagenicity of glutathione and cysteine in the Ames test.
Topics: Animals; Cysteine; Glutathione; Histidine; Hydrogen Peroxide; Kidney; Liver; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium | 1983 |
Resonance Raman spectra of copper(II)-substituted liver alcohol dehydrogenase: a type 1 copper analogue.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Binding Sites; Cations, Divalent; Copper; Cysteine; Histidine; Horses; Liver; Nickel; Pyrazoles; Spectrum Analysis, Raman | 1983 |
Evidence that copper-amino acid complexes are potent stimulators of the release of luteinizing hormone-releasing hormone from isolated hypothalamic granules.
Topics: Animals; Chelating Agents; Copper; Cysteine; Cytoplasmic Granules; Dithiothreitol; Gonadotropin-Releasing Hormone; Histidine; Hypothalamus, Middle; Kinetics; Male; Oligopeptides; Rats; Serum Albumin, Bovine; Temperature | 1984 |
Evidence for an active-center cysteine in the SH-proteinase alpha-clostripain through use of N-tosyl-L-lysine chloromethyl ketone.
Topics: Alkylating Agents; Amino Acid Chloromethyl Ketones; Binding Sites; Clostridium; Cysteine; Cysteine Endopeptidases; Histidine; Hydrogen-Ion Concentration; Protease Inhibitors; Tosyllysine Chloromethyl Ketone | 1984 |
Identification of active-site residues of sheep liver serine hydroxymethyltransferase.
Topics: Animals; Arginine; Binding Sites; Cysteine; Diethyl Pyrocarbonate; Ethylmaleimide; Glycine Hydroxymethyltransferase; Histidine; Kinetics; Liver; Phenylglyoxal; Sheep; Spectrophotometry; Transferases | 1984 |
Effect of histidine, cysteine, glutathione or beef on iron absorption in humans.
Topics: Absorption; Animals; Cattle; Cysteine; Dose-Response Relationship, Drug; Fabaceae; Female; Glutathione; Heme; Hemoglobins; Histidine; Humans; Iron; Male; Meat; Plants, Medicinal; Zea mays | 1984 |
Conserved cysteine and histidine residues in the structures of the tyrosyl and methionyl-tRNA synthetases.
Topics: Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Binding Sites; Cysteine; Escherichia coli; Geobacillus stearothermophilus; Histidine; Methionine-tRNA Ligase; Protein Conformation; Tyrosine-tRNA Ligase | 1982 |
Specific cleavage of glucosephosphate isomerases at cysteinyl residues using 2-nitro-5-thiocyanobenzoic acid: analyses of peptides eluted from polyacrylamide gels and localization of active site histidyl and lysyl residues.
Topics: Animals; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Female; Glucose-6-Phosphate Isomerase; Histidine; Humans; Lysine; Muscles; Peptide Fragments; Placenta; Pregnancy; Sulfhydryl Reagents; Swine; Thiocyanates | 1981 |
Metabolism of zinc, copper and iron as affected by dietary protein, cysteine and histidine.
Topics: Animals; Biological Availability; Body Weight; Copper; Cysteine; Dietary Proteins; Eating; Histidine; Iron; Kidney; Lactalbumin; Liver; Male; Rats; Rats, Inbred Strains; Tibia; Zinc | 1983 |
Inhibition of dihydrofolate reductase by methotrexate: a new look at an old problem.
Topics: Animals; Catalysis; Cells, Cultured; Cysteine; Folic Acid Antagonists; Histidine; Kinetics; Leukemia L1210; Methotrexate; Mice; NADP; Structure-Activity Relationship | 1980 |
Nuclear magnetic resonance and chemical modification studies of the role of the metal in yeast aldolase.
Topics: Copper; Cysteine; Diethyl Pyrocarbonate; Formates; Fructose-Bisphosphate Aldolase; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Protein Binding; Saccharomyces cerevisiae; Zinc | 1981 |
Accumulation of lead by renal slices in the presence of organic anions.
Topics: Animals; Anions; Biological Transport; Citrates; Cysteine; Cystine; Glutathione; Histidine; Kidney; Lead; Male; Rabbits | 1981 |
Bromobenzene epoxidation leading to binding on macromolecular protein sites.
Topics: Animals; Binding Sites; Bromobenzenes; Cysteine; Epoxy Compounds; Hemoglobins; Histidine; Humans; In Vitro Techniques; Male; Microsomes, Liver; Peptide Fragments; Protein Binding; Rats; Rats, Inbred Strains | 1981 |
The chemical reactivity of the histidine-195 residue in lactate dehydrogenase thiomethylated at the cysteine-165 residue.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Cysteine; Diethyl Pyrocarbonate; Formates; Histidine; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Ligands; Methyl Methanesulfonate; Pyruvates; Sulfides | 1981 |
Structure, properties, and determination of covalently bound flavins.
Topics: Cysteine; Flavins; Histidine; Peptides; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry; Structure-Activity Relationship | 1980 |
Nuclear magnetic resonance evidence for the coexistence of several conformational states of rabbit cardiac and skeletal tropomyosins.
Topics: Animals; Cysteine; Drug Stability; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Muscles; Myocardium; Protein Conformation; Rabbits; Tropomyosin | 1980 |
Metal-binding proteins in bovine and porcine hepatic and renal tissues: isolation and characterization.
Topics: Amino Acids; Animals; Cadmium; Cattle; Cysteine; Histidine; Kidney; Liver; Metalloproteins; Metallothionein; Molecular Weight; Swine; Zinc | 1980 |
Effect of cysteine-25 on the ionization of histidine-159 in papain as determined by proton nuclear magnetic resonance spectroscopy. Evidence for a his-159--Cys-25 ion pair and its possible role in catalysis.
Topics: Binding Sites; Cysteine; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Papain; Protein Binding | 1981 |
Identification of critical amino acids within the foot-and-mouth disease virus leader protein, a cysteine protease.
Topics: Amino Acid Sequence; Amino Acids; Animals; Aphthovirus; Base Sequence; Cysteine; Cysteine Endopeptidases; DNA Primers; DNA, Viral; Endopeptidases; Guinea Pigs; Histidine; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Protein Sorting Signals; Sequence Alignment; Sequence Homology, Amino Acid | 1995 |
Fluorescent labeling of purified beta 2 adrenergic receptor. Evidence for ligand-specific conformational changes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cell Line; Cysteine; Dihydroalprenolol; Fluorescent Dyes; Histidine; Humans; Isoproterenol; Kinetics; Ligands; Models, Structural; Oxadiazoles; Protein Conformation; Receptors, Adrenergic, beta-2; Recombinant Proteins; Sensitivity and Specificity; Sequence Tagged Sites; Spectrometry, Fluorescence; Spodoptera; Time Factors; Transfection | 1995 |
The Cys-His motif of Ty3 NC can be contributed by Gag3 or Gag3-Pol3 polyproteins.
Topics: Amino Acid Sequence; Base Sequence; Cysteine; DNA Transposable Elements; Gene Products, gag; Gene Products, pol; Histidine; Molecular Sequence Data; Mutation; Nucleoproteins; Oligodeoxyribonucleotides; Protein Precursors; Protein Processing, Post-Translational; RNA-Directed DNA Polymerase; Saccharomyces cerevisiae | 1994 |
Prokaryotic expression of the heme- and flavin-binding domains of rat neuronal nitric oxide synthase as distinct polypeptides: identification of the heme-binding proximal thiolate ligand as cysteine-415.
Topics: Amino Acid Oxidoreductases; Animals; Base Sequence; Cloning, Molecular; Cysteine; DNA Primers; Escherichia coli; Flavins; Heme; Hemeproteins; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurons; Nitric Oxide Synthase; Peptides; Rats | 1995 |
Trans effects on cysteine ligation in the proximal His93Cys variant of horse heart myoglobin.
Topics: Animals; Circular Dichroism; Cysteine; Cytochrome P-450 Enzyme System; Electrochemistry; Electron Spin Resonance Spectroscopy; Ferric Compounds; Heme; Histidine; Horses; Humans; Magnetic Resonance Spectroscopy; Magnetics; Myocardium; Myoglobin | 1995 |
Mutation of the metal-bridging proton-donor His63 residue in human Cu, Zn superoxide dismutase. Biochemical and biophysical analysis of the His63-->Cys mutant.
Topics: Copper; Cysteine; Enzyme Activation; Histidine; Humans; Mutation; Protons; Superoxide Dismutase; Zinc | 1995 |
Effect of adjacent histidine and cysteine residues on the spontaneous degradation of asparaginyl- and aspartyl-containing peptides.
Topics: Adrenocorticotropic Hormone; Amides; Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Cysteine; Histidine; Molecular Sequence Data; Oligopeptides; Stereoisomerism | 1995 |
The modular character of a DNA junction-resolving enzyme: a zinc-binding motif in bacteriophage T4 endonuclease VII.
Topics: Amino Acid Sequence; Bacteriophage T4; Base Sequence; Binding Sites; Cysteine; Deoxyribonuclease (Pyrimidine Dimer); Endodeoxyribonucleases; Escherichia coli; Genes, Synthetic; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Viral Proteins; Zinc | 1995 |
Identification and molecular localization of a pH-sensing domain for the inward rectifier potassium channel HIR.
Topics: Amino Acid Sequence; Animals; Cysteine; Electric Conductivity; Gene Expression; Histidine; Hydrogen-Ion Concentration; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Potassium Channels; Protons; Recombinant Fusion Proteins; Recombinant Proteins; Structure-Activity Relationship; Sulfhydryl Reagents; Xenopus laevis; Zinc | 1995 |
Phosphorescence lifetime of tryptophan in proteins.
Topics: Amino Acid Sequence; Cysteine; Glyceraldehyde-3-Phosphate Dehydrogenases; Guanidine; Guanidines; Histidine; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Luminescent Measurements; Molecular Sequence Data; Peptides; Protein Denaturation; Proteins; Tryptophan; Tyrosine; Viscosity | 1995 |
Replacements of histidine 226 of NhaA-Na+/H+ antiporter of Escherichia coli. Cysteine (H226C) or serine (H226S) retain both normal activity and pH sensitivity, aspartate (H226D) shifts the pH profile toward basic pH, and alanine (H226A) inactivates the ca
Topics: Alanine; Aspartic Acid; Codon; Cysteine; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Phenotype; Point Mutation; Serine; Sodium-Hydrogen Exchangers | 1995 |
Leader peptidase from Escherichia coli: overexpression, characterization, and inactivation by modification of tryptophan residues 300 and 310 with N-bromosuccinimide.
Topics: Amino Acid Sequence; Arginine; Base Sequence; Bromosuccinimide; Cysteine; Endopeptidases; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Membrane Proteins; Molecular Sequence Data; Serine Endopeptidases; Tryptophan; Tyrosine | 1995 |
Novel metal-binding proteins by design.
Topics: Amino Acid Sequence; Binding Sites; Cadmium; Circular Dichroism; Cobalt; Cysteine; Histidine; Immunoglobulin G; Magnetic Resonance Spectroscopy; Metalloproteins; Models, Molecular; Molecular Sequence Data; Protein Conformation; Thermodynamics; Zinc | 1995 |
Chemical modification of alpha(1-3) fucosyltransferase defines residues of catalytic importance.
Topics: Animals; Arginine; Binding Sites; Carbohydrate Sequence; Cell Line; Cloning, Molecular; Cysteine; Enzyme Inhibitors; Ethylmaleimide; Fucosyltransferases; Histidine; Humans; Kinetics; Lysine; Molecular Sequence Data; Recombinant Proteins; Spodoptera; Transfection; Tryptophan | 1995 |
Production and characterization of an analog of acidic fibroblast growth factor with enhanced stability and biological activity.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Animals; Base Sequence; Biological Assay; Cell Division; Circular Dichroism; Cysteine; Escherichia coli; Fibroblast Growth Factor 1; Glycine; Histidine; Hot Temperature; Mice; Molecular Sequence Data; Mutation; Protein Denaturation; Protein Engineering; Recombinant Proteins; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1993 |
Golgi retention mechanism of beta-1,4-galactosyltransferase. Membrane-spanning domain-dependent homodimerization and association with alpha- and beta-tubulins.
Topics: Amino Acid Sequence; Animals; Biological Transport; Cell Line, Transformed; Chlorocebus aethiops; Cysteine; Golgi Apparatus; Histidine; Membrane Proteins; Molecular Sequence Data; N-Acetyllactosamine Synthase; Protein Conformation; Recombinant Fusion Proteins; Transfection; Tubulin | 1995 |
Effect of metal ions on sucrose synthase from rice grains--a study on enzyme inhibition and enzyme topography.
Topics: Cations, Divalent; Chromatography, Affinity; Copper; Cysteine; Diethyl Pyrocarbonate; Dithiothreitol; Edetic Acid; Glucosyltransferases; Glutathione; Histidine; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Mercaptoethanol; Oryza; Seeds | 1995 |
A molecular model for the redox potential difference between thioredoxin and DsbA, based on electrostatics calculations.
Topics: Binding Sites; Calorimetry; Cysteine; Electrochemistry; Histidine; Isomerases; Models, Molecular; Oxidation-Reduction; Protein Conformation; Protein Disulfide-Isomerases; Protein Structure, Secondary; Thermodynamics; Thioredoxins | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
Evidence for an essential histidine residue located in the binding site of the cysteine-specific lysosomal transport protein.
Topics: Binding Sites; Biological Transport; Carrier Proteins; Cell Line; Cysteine; Diethyl Pyrocarbonate; Histidine; Humans; Hydrogen-Ion Concentration; Lysosomes; Phosphatidylcholines | 1995 |
The 2.8 A crystal structure of peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: a five-layered alpha beta alpha beta alpha structure constructed from two core domains of identical topology.
Topics: Acetyl-CoA C-Acyltransferase; Amino Acid Sequence; Cloning, Molecular; Computer Graphics; Conserved Sequence; Crystallography, X-Ray; Cysteine; Histidine; Macromolecular Substances; Microbodies; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Saccharomyces cerevisiae | 1994 |
Penicillin acylase has a single-amino-acid catalytic centre.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Computer Graphics; Crystallography, X-Ray; Cysteine; Escherichia coli; Histidine; Molecular Sequence Data; Penicillin Amidase; Protein Conformation; Serine | 1995 |
The proteasome from Thermoplasma acidophilum is neither a cysteine nor a serine protease.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Cell Line, Transformed; Cysteine; Cysteine Endopeptidases; Histidine; Humans; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis; Proteasome Endopeptidase Complex; Sequence Homology, Amino Acid; Serine Endopeptidases; Thermoplasma | 1995 |
The catalytic site of monogalactosyldiacylglycerol synthase from spinach chloroplast envelope membranes. Biochemical analysis of the structure and of the metal content.
Topics: Binding Sites; Cations, Divalent; Chelating Agents; Chlorides; Chloroplasts; Cysteine; Dithiothreitol; Ethylmaleimide; Galactosyltransferases; Histidine; Intracellular Membranes; Kinetics; Molecular Weight; Spinacia oleracea; Sulfur Radioisotopes; Uridine Diphosphate; Zinc; Zinc Compounds | 1995 |
Sensitivity of the essential zinc-thiolate moiety of yeast alcohol dehydrogenase to hypochlorite and peroxynitrite.
Topics: Alcohol Dehydrogenase; Cysteine; Histidine; Hydrogen Peroxide; Hypochlorous Acid; Kinetics; Molsidomine; Nitrates; Sulfhydryl Compounds; Taurine; Zinc | 1995 |
1H NMR structure and biological studies of the His23-->Cys mutant nucleocapsid protein of HIV-1 indicate that the conformation of the first zinc finger is critical for virus infectivity.
Topics: Amino Acid Sequence; Capsid; Capsid Proteins; Cysteine; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Histidine; HIV-1; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Structure-Activity Relationship; T-Lymphocytes, Regulatory; Transfection; Viral Proteins; Virulence; Zinc; Zinc Fingers | 1994 |
Effects of the micro-environment on the photophysical properties of hematoporphyrin.
Topics: Cysteine; DEAE-Dextran; Hematoporphyrins; Histidine; Photochemistry; Photochemotherapy; Povidone; Silicon Dioxide; Tyrosine | 1994 |
Modulation of the enzymatic activity of papain by interdomain residues remote from the active site.
Topics: Base Sequence; Binding Sites; Catalysis; Cysteine; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Papain; Structure-Activity Relationship | 1994 |
Identification of amino acid residues associated with the [2Fe-2S] cluster of the 25 kDa (NQO2) subunit of the proton-translocating NADH-quinone oxidoreductase of Paracoccus denitrificans.
Topics: Amino Acids; Base Sequence; Biological Transport; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Histidine; Iron-Sulfur Proteins; Metalloproteins; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Nonheme Iron Proteins; Paracoccus denitrificans; Protons; Quinone Reductases; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1994 |
Existence of the Cys-His ion-pair state of cysteine proteinases may be an insufficient condition for catalytic competence.
Topics: Catalysis; Cysteine; Ficain; Histidine; Hydrogen-Ion Concentration; Protein Binding | 1994 |
Mutagenesis of the Clostridium difficile toxin B gene and effect on cytotoxic activity.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Bacterial Toxins; CHO Cells; Clostridioides difficile; Cricetinae; Cysteine; Enterotoxins; Escherichia coli; Genes, Bacterial; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Sequence Deletion | 1994 |
Influence of six mutations of the protein C gene on the Gla domain conformation and calcium affinity.
Topics: 1-Carboxyglutamic Acid; Adult; Amino Acid Sequence; Antibodies, Monoclonal; Arginine; Aspartic Acid; Calcium; Chromatography, Ion Exchange; Cysteine; Enzyme-Linked Immunosorbent Assay; Histidine; Humans; Male; Molecular Sequence Data; Mutation; Protein C; Protein Structure, Tertiary | 1994 |
Fatty acyl transfer by human N-myristyl transferase is dependent upon conserved cysteine and histidine residues.
Topics: Acyltransferases; Amino Acid Sequence; Base Sequence; Binding Sites; Conserved Sequence; Cysteine; Escherichia coli; Fatty Acids; Histidine; Humans; Models, Molecular; Molecular Sequence Data; Oligodeoxyribonucleotides | 1994 |
Histidine-419 plays a role in energy coupling in the vesicular monoamine transporter from rat.
Topics: Animals; Arginine; Biological Transport; Cysteine; Energy Metabolism; Glycoproteins; Histidine; Membrane Glycoproteins; Membrane Transport Proteins; Mutagenesis, Site-Directed; Neuropeptides; Neurotransmitter Agents; Rats; Reserpine; Serotonin; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 1994 |
Surface labeling of key residues during assembly of the transmembrane pore formed by staphylococcal alpha-hemolysin.
Topics: Animals; Bacterial Toxins; Cysteine; Erythrocytes; Hemolysin Proteins; Histidine; Mutation; Rabbits; Staphylococcus aureus; Stilbenes | 1994 |
Structure of chymopapain M the late-eluted chymopapain deduced by comparative modelling techniques and active-centre characteristics determined by pH-dependent kinetics of catalysis and reactions with time-dependent inhibitors: the Cys-25/His-159 ion-pair
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Chymopapain; Cystatins; Cysteine; Disulfides; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Papain; Protein Structure, Tertiary; Sequence Alignment; Sequence Homology, Amino Acid | 1994 |
Identification of the essential cysteine and histidine residues of the turnip yellow mosaic virus protease.
Topics: Amino Acid Sequence; Amino Acids; Base Sequence; Brassica; Cysteine; Cysteine Endopeptidases; Histidine; Molecular Sequence Data; Peptide Mapping; Protein Processing, Post-Translational; Tymovirus; Viral Nonstructural Proteins | 1994 |
Interaction of mammalian sperm nuclear protamines and peptides derived thereof with immobilized zinc.
Topics: Amino Acid Sequence; Animals; Cell Nucleus; Chromatography, Affinity; Cysteine; Histidine; Humans; Male; Molecular Sequence Data; Peptides; Protamines; Serine; Sheep; Spermatozoa; Swine; Tyrosine; Zinc | 1994 |
Rapid exchange of subunits of mammalian ornithine decarboxylase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chromatography, Affinity; Cysteine; Histidine; Kinetics; Lysine; Macromolecular Substances; Mice; Mutagenesis, Site-Directed; Ornithine Decarboxylase; Plasmids; Point Mutation; Protein Biosynthesis; Restriction Mapping; Transcription, Genetic | 1994 |
Isolation of S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]-3-thiolactic acid, a new metabolite of histidine, from normal human urine and its formation from S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]cysteine.
Topics: Animals; Cysteine; Histidine; Humans; Imidazoles; Male; Rats; Rats, Wistar; Spectrometry, Mass, Fast Atom Bombardment | 1994 |
Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs.
Topics: Amino Acid Sequence; Computer Simulation; Cysteine; DNA; DNA-Binding Proteins; Histidine; Molecular Sequence Data; Sequence Alignment; Transcription Factors; Zinc Fingers | 1993 |
The pH-dependent behavior of catalytic activities of Azospirillum brasilense glutamate synthase and iodoacetamide modification of the enzyme provide evidence for a catalytic Cys-His ion pair.
Topics: Amino Acid Sequence; Ammonia; Azospirillum brasilense; Catalysis; Cysteine; Glutamate Synthase; Glutamine; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Ketoglutaric Acids; Kinetics; Molecular Sequence Data; NADP; Sequence Analysis | 1994 |
Varicella-zoster virus open reading frame 4 encodes a transcriptional activator that is functionally distinct from that of herpes simplex virus homology ICP27.
Topics: Base Sequence; Cysteine; Gene Expression Regulation, Viral; Herpesvirus 3, Human; Histidine; Immediate-Early Proteins; Molecular Sequence Data; Open Reading Frames; Promoter Regions, Genetic; RNA Processing, Post-Transcriptional; Structure-Activity Relationship; Transcription Factors; Viral Proteins | 1994 |
An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs.
Topics: Amino Acid Sequence; Animals; Apoptosis; Base Sequence; Cysteine; DNA, Recombinant; Genes, Viral; Genetic Complementation Test; Histidine; Inhibitor of Apoptosis Proteins; Molecular Sequence Data; Moths; Nucleopolyhedroviruses; Restriction Mapping; Sequence Homology, Amino Acid; Species Specificity; Viral Proteins | 1994 |
Structure of a histidine-X4-histidine zinc finger domain: insights into ADR1-UAS1 protein-DNA recognition.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Cysteine; DNA; DNA-Binding Proteins; Histidine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutation; Protein Conformation; Saccharomyces cerevisiae Proteins; Solutions; Transcription Factors; Zinc Fingers | 1994 |
Formation of intersubunit disulfide bonds and properties of the single histidine and cysteine residues in each subunit relative to the decameric structure of cyanase.
Topics: Base Sequence; Binding Sites; Carbon-Nitrogen Lyases; Cysteine; Disulfides; Enzyme Stability; Histidine; Lyases; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Conformation | 1994 |
Requirement of the Pro-Cys-His-Arg sequence for O6-methylguanine-DNA methyltransferase activity revealed by saturation mutagenesis with negative and positive screening.
Topics: Alkylating Agents; Amino Acid Sequence; Arginine; Bacterial Proteins; Base Sequence; Blotting, Western; Consensus Sequence; Cysteine; DNA Repair; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Histidine; Methylation; Methyltransferases; Molecular Sequence Data; Mutagenesis, Site-Directed; O(6)-Methylguanine-DNA Methyltransferase; Point Mutation; Proline; Sequence Analysis | 1994 |
Specific amino acids modulate the embryotoxicity of nickel chloride and its transfer to the rat embryo in vitro.
Topics: Amino Acids; Animals; Aspartic Acid; Biological Transport; Cysteine; Embryo, Mammalian; Embryonic and Fetal Development; Female; Histidine; Nickel; Organ Culture Techniques; Pregnancy; Protein Binding; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1993 |
Characterisation of a novel cysteine/histidine-rich metal binding domain from Xenopus nuclear factor XNF7.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chelating Agents; Circular Dichroism; Cysteine; DNA-Binding Proteins; Egg Proteins; Egtazic Acid; Histidine; Magnetic Resonance Spectroscopy; Metals; Molecular Sequence Data; Nuclear Proteins; Phosphoproteins; Protein Binding; Xenopus; Xenopus Proteins | 1993 |
Chromosomal localization of 9 KOX zinc finger genes: physical linkages suggest clustering of KOX genes on chromosomes 12, 16, and 19.
Topics: Chromosome Mapping; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 19; Cysteine; DNA Probes; Electrophoresis, Gel, Pulsed-Field; Genes; Histidine; Humans; In Situ Hybridization; Male; Molecular Sequence Data; Multigene Family; Zinc Fingers | 1993 |
Krab domains analyzed in human Cys/His-type zinc-finger proteins KOX 1, KOX 8, and KOX 19.
Topics: Amino Acid Sequence; Chromosome Mapping; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 7; Cysteine; DNA-Binding Proteins; Histidine; Humans; Molecular Sequence Data; Multigene Family; Zinc Fingers | 1993 |
Potentiation of 45Ca uptake and acute toxicity mediated by the N-methyl-D-aspartate receptor: the effect of metal binding agents and transition metal ions.
Topics: Animals; Calcium; Calcium Radioisotopes; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Edetic Acid; Histidine; Kinetics; Magnesium; Metals; N-Methylaspartate; Nickel; Palladium; Rats; Receptors, N-Methyl-D-Aspartate; Serum Albumin, Bovine; Zinc | 1993 |
Thiols, gold-thiols, zinc-thiols and the redox state of hemoglobin.
Topics: Binding Sites; Binding, Competitive; Copper; Cysteine; Gold; Hemoglobins; Histidine; Humans; Organometallic Compounds; Oxidation-Reduction; Thiomalates; Zinc | 1993 |
Role of the His-Cys finger of Moloney murine leukemia virus integrase protein in integration and disintegration.
Topics: Amino Acid Sequence; Base Sequence; Cysteine; Deoxyribonuclease I; DNA Nucleotidyltransferases; DNA, Viral; Ethylmaleimide; Histidine; Integrases; Kinetics; Models, Structural; Molecular Sequence Data; Moloney murine leukemia virus; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Recombinant Proteins; Repetitive Sequences, Nucleic Acid; Substrate Specificity; Virus Integration | 1993 |
Active site labeling of the Yersinia protein tyrosine phosphatase: the determination of the pKa of the active site cysteine and the function of the conserved histidine 402.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cysteine; DNA, Single-Stranded; Histidine; Hydrogen-Ion Concentration; Iodoacetates; Iodoacetic Acid; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Tyrosine Phosphatases; Yersinia | 1993 |
Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Gene Products, gag; Genes, gag; HeLa Cells; Histidine; HIV-1; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Protein Binding; Protein Precursors; RNA, Viral; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Viral Structural Proteins; Virus Replication | 1993 |
Avian retroviral RNA encapsidation: reexamination of functional 5' RNA sequences and the role of nucleocapsid Cys-His motifs.
Topics: Animals; Avian Leukosis Virus; Base Sequence; Capsid; Cell Line; Cysteine; Genes, gag; Histidine; Molecular Sequence Data; Nucleic Acid Conformation; Quail; Regulatory Sequences, Nucleic Acid; RNA Splicing; RNA, Viral; Virion | 1993 |
Roles of proximal ligand in heme proteins: replacement of proximal histidine of human myoglobin with cysteine and tyrosine by site-directed mutagenesis as models for P-450, chloroperoxidase, and catalase.
Topics: Benzene Derivatives; Binding Sites; Catalase; Chloride Peroxidase; Cysteine; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Heme; Histidine; Humans; Iron; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Myoglobin; Spectrophotometry; Spectrum Analysis, Raman; Tyrosine | 1993 |
Effect of rearrangements and duplications of the Cys-His motifs of Rous sarcoma virus nucleocapsid protein.
Topics: Amino Acid Sequence; Avian Sarcoma Viruses; Base Sequence; Cysteine; Gene Products, gag; Gene Rearrangement; Genome, Viral; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Precursors; Repetitive Sequences, Nucleic Acid; RNA, Viral; Transfection | 1993 |
Generation of free radicals in reactions of Ni(II)-thiol complexes with molecular oxygen and model lipid hydroperoxides.
Topics: Acetylcysteine; Benzene Derivatives; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Histidine; Lipid Peroxides; Nickel; Oxygen; Penicillamine; Peroxides; Sulfhydryl Compounds; tert-Butylhydroperoxide | 1993 |
Two cysteines, two histidines, and one methionine are ligands of a binuclear purple copper center.
Topics: Amino Acid Sequence; Base Sequence; Copper; Cysteine; DNA; Electron Transport Complex IV; Electrophoresis, Polyacrylamide Gel; Histidine; Ligands; Mass Spectrometry; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases; Phenotype; Protein Engineering | 1993 |
Identification of the catalytic sites of a papain-like cysteine proteinase of murine coronavirus.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cysteine; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Genes, Viral; Histidine; Molecular Sequence Data; Molecular Weight; Murine hepatitis virus; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Open Reading Frames; Papain; Polymerase Chain Reaction; Protein Biosynthesis; Protein Processing, Post-Translational; Rabbits; Recombinant Proteins; Restriction Mapping; Reticulocytes; Sequence Deletion | 1993 |
Replacement of His23 by Cys in a zinc finger of HIV-1 NCp7 led to a change in 1H NMR-derived 3D structure and to a loss of biological activity.
Topics: Amino Acid Sequence; Capsid Proteins; Cysteine; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Histidine; HIV-1; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protons; Viral Proteins; Zinc Fingers | 1993 |
Inhibition of HIV-1 infectivity by zinc-ejecting aromatic C-nitroso compounds.
Topics: Amino Acid Sequence; Antiviral Agents; Benzamides; Binding Sites; Capsid; Coumarins; Cysteine; Gene Products, gag; Histidine; HIV-1; Humans; Lymphocytes; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nitroso Compounds; Zinc; Zinc Fingers | 1993 |
Engineering the zinc binding site of human carbonic anhydrase II: structure of the His-94-->Cys apoenzyme in a new crystalline form.
Topics: Amino Acid Sequence; Apoenzymes; Binding Sites; Carbonic Anhydrases; Cloning, Molecular; Cysteine; Escherichia coli; Histidine; Humans; Hydrogen Bonding; Isoenzymes; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Engineering; Recombinant Proteins; Spectrophotometry; X-Ray Diffraction; Zinc | 1993 |
Identification of zinc-binding ligands in the class II fructose-1,6-bisphosphate aldolase of Escherichia coli.
Topics: Amino Acid Sequence; Cysteine; Escherichia coli; Fructose-Bisphosphate Aldolase; Histidine; Ligands; Molecular Sequence Data; Plasmids; Sequence Homology, Amino Acid; Zinc | 1993 |
The pKa of the catalytic histidine residue of chloramphenicol acetyltransferase.
Topics: Benzenesulfonates; Binding Sites; Catalysis; Chloramphenicol O-Acetyltransferase; Cysteine; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics | 1993 |
Ionization characteristics of the Cys-25/His-159 interactive system and of the modulatory group of papain: resolution of ambiguity by electronic perturbation of the quasi-2-mercaptopyridine leaving group in a new pyrimidyl disulphide reactivity probe.
Topics: Binding Sites; Catalysis; Cysteine; Disulfides; Electrochemistry; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Papain; Pyridines; Sulfhydryl Reagents | 1993 |
Catalytic-site characteristics of the porcine calpain II 80 kDa/18 kDa heterodimer revealed by selective reaction of its essential thiol group with two-hydronic-state time-dependent inhibitors: evidence for a catalytic site Cys/His interactive system and
Topics: Animals; Binding Sites; Calcium; Calpain; Catalysis; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Histidine; Hydrogen Bonding; Kinetics; Macromolecular Substances; Molecular Weight; Sulfhydryl Compounds; Swine | 1993 |
Affinity labeling identifies histidine at the active site of human placental 3 beta-hydroxysteroid dehydrogenase and steroid 5-->4-ene-isomerase.
Topics: 3-Hydroxysteroid Dehydrogenases; Affinity Labels; Alkylation; Binding Sites; Binding, Competitive; Cysteine; Enzyme Activation; Female; Histidine; Humans; Hydroxyprogesterones; Placenta; Pregnenolone; Steroid Isomerases | 1993 |
1H NMR of albumin in human blood plasma: drug binding and redox reactions at Cys34.
Topics: Alcohol Deterrents; Antihypertensive Agents; Antirheumatic Agents; Auranofin; Binding Sites; Blood Proteins; Captopril; Cysteine; Disulfides; Disulfiram; Gold Sodium Thiomalate; Histidine; Humans; Isoelectric Point; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Oxidation-Reduction; Protein Binding; Serum Albumin | 1995 |
Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant.
Topics: 3T3 Cells; Animals; Arginine; Cell Line; Chronic Disease; Cysteine; Cytoskeleton; Disease Models, Animal; Glycoproteins; Glycosylation; Hepatitis, Animal; Histidine; HT29 Cells; Humans; Intermediate Filament Proteins; Keratins; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Phosphorylation; Solubility; Spodoptera | 1995 |
Restoration of pore-forming activity in staphylococcal alpha-hemolysin by targeted covalent modification.
Topics: Animals; Bacterial Toxins; Cysteine; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Hemolysin Proteins; Histidine; Iodoacetamide; Mutagenesis, Site-Directed; Point Mutation; Porins; Protein Engineering; Rabbits; Staphylococcus; Temperature | 1995 |
The effect of histidine and cysteine on zinc influx into rat and human erythrocytes.
Topics: Animals; Cysteine; Dose-Response Relationship, Drug; Erythrocytes; Histidine; Humans; Rats; Rats, Wistar; Time Factors; Zinc | 1995 |
The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Binding Sites; Copper; Cysteine; Cystine; Electron Transport; Ferric Compounds; Histidine; Humans; Hydrogen Peroxide; Hydroxyl Radical; Mass Spectrometry; Oligopeptides; Oxidation-Reduction; Peptide Fragments; Recombinant Fusion Proteins; Superoxides | 1996 |
Identification of the active-site peptide of 2,3-dihydroxybenzoic acid decarboxylase from Aspergillus oryzae.
Topics: Amino Acid Sequence; Aspergillus oryzae; Benzoates; Binding Sites; Carboxy-Lyases; Catalysis; Cysteine; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Ethylmaleimide; Histidine; Hydrogen-Ion Concentration; Indoles; Kinetics; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet | 1996 |
Human p300 protein is a coactivator for the transcription factor MyoD.
Topics: Cysteine; Enhancer Elements, Genetic; Histidine; Humans; Macromolecular Substances; MyoD Protein; Nuclear Proteins; Promoter Regions, Genetic; Protein Binding; Sequence Deletion; Structure-Activity Relationship; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation | 1996 |
A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cysteine; DNA-Binding Proteins; DNA, Complementary; Histidine; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Multigene Family; Nerve Tissue Proteins; Nervous System; Pituitary Gland; Rats; RNA Splicing; Sequence Homology, Amino Acid; Trans-Activators; Transcription Factors; Zinc Fingers | 1996 |
The catalytic cysteine and histidine in the plant acyl-acyl carrier protein thioesterases.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Conserved Sequence; Cysteine; DNA Primers; Enzyme Inhibitors; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Plants; Point Mutation; Polymerase Chain Reaction; Recombinant Proteins; Sequence Homology, Amino Acid; Thiolester Hydrolases | 1996 |
Characterization of the electrostatic perturbation of a catalytic site (Cys)-S-/(His)-Im+H ion-pair in one type of serine proteinase architecture by kinetic and computational studies on chemically mutated subtilisin variants.
Topics: 2,2'-Dipyridyl; Bacillus subtilis; Binding Sites; Computer Simulation; Cysteine; Disulfides; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Structure; Mutagenesis; Protein Conformation; Pyrimidines; Subtilisins; Sulfhydryl Compounds; Sulfhydryl Reagents | 1996 |
Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization.
Topics: Amino Acid Sequence; Animals; Asparagine; Base Sequence; Bleomycin; Cell Line; Cloning, Molecular; Conserved Sequence; Cysteine; Cysteine Endopeptidases; DNA Primers; DNA, Complementary; Drug Resistance, Neoplasm; Gene Expression; Histidine; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Polymerase Chain Reaction; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Spodoptera; Substrate Specificity; Transfection | 1996 |
Isolation of the murine S100 protein MRP14 (14 kDa migration-inhibitory-factor-related protein) from activated spleen cells: characterization of post-translational modifications and zinc binding.
Topics: Acetylation; Amino Acid Sequence; Animals; Antigens, Differentiation; Calcium-Binding Proteins; Calgranulin B; Cells, Cultured; Chromatography, High Pressure Liquid; Concanavalin A; Cysteine; Disulfides; Gene Expression Regulation; Histidine; Humans; Lymphocyte Activation; Lymphocytes; Mass Spectrometry; Methionine; Methylation; Mice; Molecular Sequence Data; Neutrophils; Peptide Fragments; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Spleen; Zinc | 1996 |
The design of an alternative, covalently flavinylated 6-hydroxy-D-nicotine oxidase by replacing the FAD-binding histidine by cysteine and reconstitution of the holoenzyme with 8-(methylsulfonyl)FAD.
Topics: Coenzymes; Cysteine; Drug Design; Flavin-Adenine Dinucleotide; Flavins; Histidine; Kinetics; Oxidoreductases; Point Mutation; Structure-Activity Relationship | 1996 |
Studies on identifying the catalytic role of Glu-204 in the active site of yeast invertase.
Topics: Amino Acid Sequence; Bacteria; Base Sequence; beta-Fructofuranosidase; Binding Sites; Catalysis; Cysteine; Dithiothreitol; Glutamic Acid; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Iodine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Plants; Point Mutation; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid | 1996 |
Requirement for two conserved cysteine residues in the Ada protein of Escherichia coli for transactivation of the ada promoter.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Conserved Sequence; Cysteine; DNA Primers; Escherichia coli; Escherichia coli Proteins; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Promoter Regions, Genetic; Transcription Factors; Transcriptional Activation | 1996 |
Gip-2 codon 179 oncogene mutations: absent in adrenal cortical tumors.
Topics: Adenoma; Adrenal Cortex Neoplasms; Arginine; Base Sequence; Carcinoma; Codon; Cysteine; DNA Restriction Enzymes; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine Triphosphate; Histidine; Humans; Molecular Sequence Data; Oncogenes; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length | 1996 |
Formation of the amino acid-DNA complexes by hexavalent and trivalent chromium in vitro: importance of trivalent chromium and the phosphate group.
Topics: Amino Acids; Ascorbic Acid; Chromium; Cross-Linking Reagents; Cysteine; Deoxyribonucleosides; Deoxyribonucleotides; DNA; DNA Adducts; Guanosine Monophosphate; Histidine; Kinetics; Models, Chemical; Phosphates; Spectrophotometry | 1996 |
Identification of essential residues for the catalytic function of 85-kDa cytosolic phospholipase A2. Probing the role of histidine, aspartic acid, cysteine, and arginine.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Aspartic Acid; Biological Evolution; Catalysis; Conserved Sequence; Cysteine; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phospholipases A; Phospholipases A2; Sequence Homology, Amino Acid | 1996 |
Characterizations of diverse residue clusters in protein three-dimensional structures.
Topics: Cysteine; Histidine; Hydrogen-Ion Concentration; Ions; Metalloproteins; Models, Molecular; Protein Structure, Tertiary; Proteins; Structure-Activity Relationship | 1996 |
Magnetic and optical properties of copper-substituted alcohol dehydrogenase: a bisthiolate copper (II) complex.
Topics: Alcohol Dehydrogenase; Animals; Circular Dichroism; Copper; Cysteine; Electron Spin Resonance Spectroscopy; Histidine; Horses; Ligands; Liver; Metalloproteins; Models, Chemical; NAD; Normal Distribution; Pyrazoles; Water | 1996 |
Evidence for the presence of essential histidine and cysteine residues in platelet cGMP-inhibited phosphodiesterase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Monophosphate; Binding Sites; Blood Platelets; Catalysis; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Ethylmaleimide; Histidine; Humans; Kinetics; Phosphodiesterase Inhibitors | 1996 |
Cys102 and His398 are required for bleomycin-inactivating activity but not for hexamer formation of yeast bleomycin hydrolase.
Topics: Base Sequence; Biopolymers; Bleomycin; Cloning, Molecular; Cysteine; Cysteine Endopeptidases; DNA, Recombinant; Escherichia coli; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Saccharomyces cerevisiae | 1996 |
A new Cys2/His2 zinc finger gene, rKr1, expressed in oligodendrocytes and neurons.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Cysteine; DNA, Complementary; Gene Expression Regulation; Gene Library; Genetic Code; Histidine; Molecular Sequence Data; Neurons; Oligodendroglia; Optic Nerve; Rats; Zinc Fingers | 1996 |
Woodward's reagent K inactivation of Escherichia coli L-threonine dehydrogenase: increased absorbance at 340-350 nm is due to modification of cysteine and histidine residues, not aspartate or glutamate carboxyl groups.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Cysteine; Enzyme Inhibitors; Escherichia coli; Glutamic Acid; Histidine; Isoxazoles; Kinetics; Models, Chemical; Molecular Sequence Data; Solvents; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 1996 |
Identification of histidine 31 and cysteine 95 in the active site of self-incompatibility associated S6-RNase in Nicotiana alata.
Topics: Amino Acid Sequence; Binding Sites; Chromosome Mapping; Cysteine; Enzyme Inhibitors; Genes, Plant; Histidine; Iodoacetates; Iodoacetic Acid; Molecular Sequence Data; Nicotiana; Plants, Toxic; Polymorphism, Genetic; Ribonucleases | 1995 |
Evidence for the interaction of avian 3-hydroxy-3-methylglutaryl-CoA synthase histidine 264 with acetoacetyl-CoA.
Topics: Acyl Coenzyme A; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Birds; Cysteine; DNA Primers; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Hydroxymethylglutaryl-CoA Synthase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Alignment | 1996 |
Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Chromatography, Ion Exchange; Cloning, Molecular; Conserved Sequence; Cysteine; DNA Helicases; DNA Probes; Escherichia coli; Fungal Proteins; Glutamic Acid; Histidine; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; RNA Helicases; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trans-Activators | 1996 |
Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover.
Topics: Amino Acid Sequence; Base Sequence; Cysteine; DNA Helicases; DNA Primers; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Histidine; Kinetics; Models, Genetic; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Peptide Chain Termination, Translational; Polymerase Chain Reaction; Protein Biosynthesis; Recombinant Proteins; RNA Helicases; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Deletion; Suppression, Genetic; Transcription, Genetic | 1996 |
Coordination of the [2Fe-2S] cluster in wild type and molecular variants of Clostridium pasteurianum ferredoxin, investigated by ESEEM spectroscopy.
Topics: Clostridium; Cysteine; Deuterium Oxide; Electron Spin Resonance Spectroscopy; Escherichia coli; Ferredoxins; Histidine; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Recombinant Proteins; Water | 1996 |
Preparation and reactions of myoglobin mutants bearing both proximal cysteine ligand and hydrophobic distal cavity: protein models for the active site of P-450.
Topics: Acetophenones; Aniline Compounds; Benzene Derivatives; Binding Sites; Cysteine; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Heme; Hemeproteins; Histidine; Humans; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Mutagenesis, Site-Directed; Myoglobin; Protein Conformation; Recombinant Proteins; Spectrophotometry, Ultraviolet; Sulfoxides | 1996 |
Studies on the enhancement of the reactivity of the (Cys-25)-S-/(His159)-Im+H ion-pair of papain by deprotonation across pKa 4.
Topics: Binding Sites; Cysteine; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Ions; Kinetics; Molecular Structure; Papain | 1996 |
Expression and purification of a recombinant metal-binding T4 lysozyme fusion protein.
Topics: Cysteine; Enzyme Stability; Escherichia coli; Histidine; Metals; Muramidase; Mutation; Peptide Fragments; Recombinant Fusion Proteins | 1996 |
Woodward's reagent K reacts with histidine and cysteine residues in Escherichia coli and Saccharomyces cerevisiae phosphoenolpyruvate carboxykinases.
Topics: Amino Acids; Binding Sites; Cysteine; Escherichia coli; Histidine; Indicators and Reagents; Isoxazoles; Kinetics; Phosphoenolpyruvate Carboxykinase (GTP); Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet | 1996 |
Isolation and characterization of N-acetyl-S-[2-carboxy-1-(1 H-imidazol-4-yl) ethyl]-L-cysteine, a new metabolite of histidine, from normal human urine and its formation from S-[2-carboxy-1-(1 H-imidazol-4-yl) ethyl]-L-cysteine.
Topics: Acetylation; Acetylcysteine; Acetyltransferases; Amino Acids; Animals; Chromatography, Ion Exchange; Cysteine; Histidine; Humans; Imidazoles; Kidney; Liver; Male; Models, Chemical; Organ Specificity; Rats; Rats, Wistar; Stereoisomerism; Urocanic Acid | 1996 |
Nucleotide and amino acid sequence analysis of the porcine adenovirus 23K protein.
Topics: Adenoviruses, Human; Amino Acid Sequence; Animals; Base Sequence; Capsid; Capsid Proteins; Cattle; Conserved Sequence; Cysteine; Cysteine Endopeptidases; Histidine; Humans; Mastadenovirus; Molecular Sequence Data; Molecular Weight; Open Reading Frames; Proline; Sequence Homology, Amino Acid; Swine; Viral Proteins | 1996 |
Electrostatic interactions in the active site of the N-terminal thioredoxin-like domain of protein disulfide isomerase.
Topics: Binding Sites; Cysteine; Disulfides; Histidine; Hydrogen-Ion Concentration; Isomerases; Osmolar Concentration; Protein Disulfide-Isomerases; Static Electricity; Thioredoxins | 1996 |
Metal binding properties and secondary structure of the zinc-binding domain of Nup475.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chromatography, High Pressure Liquid; Cloning, Molecular; Cobalt; Cysteine; DNA-Binding Proteins; Escherichia coli; Histidine; Humans; Immediate-Early Proteins; Magnetic Resonance Spectroscopy; Mammals; Models, Structural; Molecular Sequence Data; Peptide Fragments; Protein Structure, Secondary; Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Spectrophotometry; Tristetraprolin; Zinc | 1996 |
Biochemical studies of Saccharomyces cerevisiae myristoyl-coenzyme A:protein N-myristoyltransferase mutants.
Topics: Acyltransferases; Amino Acid Sequence; Cysteine; Fungal Proteins; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity; Temperature | 1996 |
His-8 lowers the pKa of the essential Cys-12 residue of the ArsC arsenate reductase of plasmid R773.
Topics: Adenosine Triphosphatases; Arsenite Transporting ATPases; Codon; Cysteine; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Ion Pumps; Kinetics; Membrane Proteins; Multienzyme Complexes; Mutagenesis; Oxidation-Reduction; Plasmids; Structure-Activity Relationship | 1996 |
Mutational analysis of human uroporphyrinogen decarboxylase.
Topics: Amino Acid Sequence; Animals; Cysteine; Ethylmaleimide; Histidine; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Uroporphyrinogen Decarboxylase | 1996 |
Comparison of the properties of native and pentaammineruthenium(III)-modified xylanase.
Topics: Alcohol Oxidoreductases; Amines; Amino Acids; Bacteria; Chromatography, High Pressure Liquid; Cysteine; Electrophoresis, Polyacrylamide Gel; Glutathione; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Oxidation-Reduction; Peptides; Ruthenium Compounds; Xylan Endo-1,3-beta-Xylosidase; Xylans; Xylose; Xylosidases | 1996 |
Conversion of cysteinyl residues to unnatural amino acid analogs. Examination in a model system.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Halogens; Histidine; Imidazoles; Kinetics; Mutagenesis, Site-Directed; Proteins | 1996 |
Studies on the biosynthesis of ovothiol A. Identification of 4-mercaptohistidine as an intermediate.
Topics: Alkynes; Amino Acids, Sulfur; Ammonium Sulfate; Animals; Crithidia fasciculata; Cysteine; Glutamates; Glycine; Histidine; Magnetic Resonance Spectroscopy; Methylhistidines; Methyltransferases; Pargyline; Sulfhydryl Compounds; Sulfur | 1996 |
Abnormal proteolytic processing of von Willebrand factor Arg611 Cys and Arg611His.
Topics: Arginine; Cysteine; Female; Histidine; Humans; Male; Point Mutation; von Willebrand Factor | 1997 |
Chemical modification of an alpha 3-fucosyltransferase; definition of amino acid residues essential for enzyme activity.
Topics: Amino Acid Sequence; Cysteine; Diethyl Pyrocarbonate; Ethylmaleimide; Fucosyltransferases; Guanosine Diphosphate Fucose; Histidine; Humans; Molecular Sequence Data; Sequence Alignment | 1997 |
Design and synthesis of substrate-derived n-acylaminoalkyl 2-pyridyl disulphides as probes of cysteine proteinase mechanism.
Topics: Binding Sites; Cysteine; Cysteine Endopeptidases; Disulfides; Drug Design; Histidine; Hydrogen Bonding; Models, Chemical; Pyridines; Static Electricity; Structure-Activity Relationship; Substrate Specificity | 1997 |
Serine319 and 321 are functional in isocitrate lyase from Escherichia coli.
Topics: Alanine; Asparagine; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Bacterial; Glycine; Histidine; Isocitrate Lyase; Isocitrates; Kinetics; Magnesium; Mutagenesis, Site-Directed; Oligonucleotides; Plasmids; Proline; Sequence Alignment; Serine; Threonine | 1997 |
Carbonyl reducing 17 beta-hydroxysteroid dehydrogenase from the filamentous fungus Cochliobolus lunatus.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Androstenedione; Ascomycota; Binding Sites; Binding, Competitive; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Histidine; Hydroxysteroid Dehydrogenases; Immunoblotting; Kinetics; Lysine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Tetranitromethane; Trinitrobenzenesulfonic Acid; Tyrosine; Vitamin K | 1997 |
Structural and functional aspects of rat microsomal glutathione transferase. The roles of cysteine 49, arginine 107, lysine 67, histidine, and tyrosine residues.
Topics: Amino Acid Sequence; Animals; Arginine; Cysteine; Enzyme Inhibitors; Glutathione Transferase; Histidine; Indicators and Reagents; Lysine; Male; Microsomes, Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylglyoxal; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Trinitrobenzenesulfonic Acid; Tyrosine | 1997 |
A 4-term energy level scheme for the high-spin ferrous hemoproteins: evidence for the 5E eta, and 5B2 terms as the ground multiplets in hemoproteins with a histidine and a cysteine protein-derived heme ligand, respectively.
Topics: Animals; Chloride Peroxidase; Circular Dichroism; Computer Simulation; Cysteine; Cytochrome P-450 Enzyme System; Heme; Histidine; Horseradish Peroxidase; Imidazoles; In Vitro Techniques; Magnetic Resonance Spectroscopy; Models, Chemical; Myoglobin; Spectroscopy, Mossbauer; Temperature; Thermodynamics | 1997 |
A Ni2+ binding motif is the basis of high affinity transport of the Alcaligenes eutrophus nickel permease.
Topics: Alcaligenes; Alkaline Phosphatase; Amino Acid Sequence; Antiporters; Aspartic Acid; ATP-Binding Cassette Transporters; Bacterial Proteins; Binding Sites; Biological Transport; Carrier Proteins; Cysteine; Escherichia coli; Escherichia coli Proteins; Histidine; Hydrogenase; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Nickel | 1997 |
The helicase domain of phage P4 alpha protein overlaps the specific DNA binding domain.
Topics: Adenosine Triphosphatases; Binding Sites; Cysteine; DNA Helicases; DNA Primase; DNA-Binding Proteins; Glycine; Histidine; Lysine; Mutation; Recombinant Fusion Proteins; RNA Nucleotidyltransferases; Substrate Specificity; Thioredoxins; Viral Proteins | 1997 |
Genetic and clinical description of hemochromatosis probands and heterozygotes: evidence that multiple genes linked to the major histocompatibility complex are responsible for hemochromatosis.
Topics: Adult; Alleles; Aspartic Acid; Chromosomes, Human, Pair 6; Cysteine; Female; Gene Frequency; Genes, MHC Class I; Genetic Linkage; Hemochromatosis; Heterozygote; Histidine; Histocompatibility Testing; HLA Antigens; Homozygote; Humans; Iron; Male; Middle Aged; Mutation; Tyrosine; White People | 1997 |
In vivo mutational analysis of highly conserved amino acid residues of the small subunit Cpa1p of the carbamylphosphate synthetase of Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Ammonia; Ammonium Sulfate; Arginine; Aspartic Acid; Carbon-Nitrogen Ligases; Chromosome Mapping; Cysteine; Gene Expression; Glutaminase; Glutamine; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Proline; Saccharomyces cerevisiae; Sequence Analysis; Sequence Deletion; Transformation, Genetic | 1997 |
Crystal structure of the wild-type human procathepsin B at 2.5 A resolution reveals the native active site of a papain-like cysteine protease zymogen.
Topics: Amino Acid Sequence; Binding Sites; Cathepsin B; Crystallography, X-Ray; Cysteine; Enzyme Activation; Enzyme Precursors; Histidine; Humans; Models, Molecular; Molecular Sequence Data; Papain; Protein Conformation; Protein Structure, Secondary | 1997 |
Regeneration studies of an analog of ribonuclease A missing disulfide bonds 65-72 and 40-95.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Confidence Intervals; Cysteine; Disulfides; Glutathione; Glutathione Disulfide; Histidine; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Pancreas; Point Mutation; Protein Folding; Recombinant Proteins; Ribonuclease, Pancreatic; Thermodynamics | 1997 |
Evidence for a cysteine-histidine thioether bridge in functional units of molluscan haemocyanins and location of the disulfide bridges in functional units d and g of the betaC-haemocyanin of Helix pomatia.
Topics: Amino Acid Sequence; Amino Acids; Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Consensus Sequence; Copper; Cysteine; Disulfides; Helix, Snails; Hemocyanins; Histidine; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Octopodiformes; Pepsin A; Peptide Fragments; Sequence Analysis; Spectrophotometry; Sulfides | 1997 |
Mutational analysis of the herpes simplex virus type 1 ICP0 C3HC4 zinc ring finger reveals a requirement for ICP0 in the expression of the essential alpha27 gene.
Topics: Animals; Cell Nucleus; Cells, Cultured; Chlorocebus aethiops; Cysteine; DNA, Viral; Gene Expression Regulation, Viral; Genes, Viral; Herpesvirus 1, Human; Histidine; Immediate-Early Proteins; Mutagenesis, Site-Directed; RNA, Viral; Structure-Activity Relationship; Ubiquitin-Protein Ligases; Vero Cells; Viral Proteins; Viral Structural Proteins; Virus Replication; Zinc Fingers | 1997 |
The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: a three-helix bundle stabilized by zinc.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chlorides; Cysteine; DNA; Enzyme Stability; Histidine; HIV Integrase; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Folding; Recombinant Fusion Proteins; Solutions; Zinc; Zinc Compounds | 1997 |
Distinct functions and requirements for the Cys-His boxes of the human immunodeficiency virus type 1 nucleocapsid protein during RNA encapsidation and replication.
Topics: Amino Acid Sequence; Capsid; Capsid Proteins; Cell Line, Transformed; Cysteine; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Genome, Viral; Histidine; HIV-1; Humans; Molecular Sequence Data; Mutagenesis; RNA, Viral; Viral Proteins; Virus Assembly; Virus Replication | 1997 |
Possible involvement of cysteine and histidine residues in the (NH4+ + Na+)-activated ATPase of an anaerobic alkaliphile, Amphibacillus xylanus.
Topics: Adenosine Triphosphatases; Bacteria, Anaerobic; Binding Sites; Cysteine; Histidine; Structure-Activity Relationship | 1998 |
Replacement of the active site tyrosine of vaccinia DNA topoisomerase by glutamate, cysteine or histidine converts the enzyme into a site-specific endonuclease.
Topics: Binding Sites; Cysteine; DNA; DNA Topoisomerases, Type I; DNA, Superhelical; Endonucleases; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mutagenesis; Structure-Activity Relationship; Tyrosine; Vaccinia virus | 1998 |
Cys2/His2 zinc-finger protein family of petunia: evolution and general mechanism of target-sequence recognition.
Topics: Amino Acid Sequence; Binding Sites; Cloning, Molecular; Conserved Sequence; Cysteine; DNA; DNA-Binding Proteins; Evolution, Molecular; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phylogeny; Plant Proteins; Plants; Sequence Alignment; Structure-Activity Relationship; Zinc Fingers | 1998 |
Metal ion binding to a zinc finger peptide containing the Cys-X2-Cys-X4-His-X4-Cys domain of a nucleic acid binding protein encoded by the Drosophila Fw-element.
Topics: Animals; Cobalt; Cysteine; DNA-Binding Proteins; Drosophila melanogaster; Histidine; Magnetic Resonance Spectroscopy; Metals; Peptide Fragments; Protein Binding; Spectrophotometry; Zinc; Zinc Fingers | 1998 |
Novel mutations at a CpG dinucleotide in the ryanodine receptor in malignant hyperthermia.
Topics: Amino Acid Substitution; Arginine; CpG Islands; Cysteine; Female; Genotype; Histidine; Humans; Male; Malignant Hyperthermia; Mutation; Pedigree; Phenotype; Ryanodine Receptor Calcium Release Channel | 1998 |
Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Biological Transport; Cell Compartmentation; Cell Nucleus; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cysteine; DNA-Binding Proteins; DNA, Fungal; Fungal Proteins; Gene Expression Regulation, Fungal; Histidine; Molecular Sequence Data; Protein Binding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Signal Transduction; Time Factors; Transcription Factors; Zinc Fingers | 1998 |
Mutagenesis study of the glycosylphosphatidylinositol phospholipase C of Trypanosoma brucei.
Topics: 4-Chloromercuribenzenesulfonate; Amino Acid Sequence; Animals; Bacillus cereus; Binding Sites; Cysteine; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Escherichia coli; Glycosylphosphatidylinositol Diacylglycerol-Lyase; Histidine; Listeria monocytogenes; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Recombinant Proteins; Sequence Alignment; Sulfhydryl Reagents; Trypanosoma brucei brucei; Type C Phospholipases | 1997 |
Interdomain information transfer during substrate activation of yeast pyruvate decarboxylase: the interaction between cysteine 221 and histidine 92.
Topics: Cysteine; Enzyme Activation; Escherichia coli; Genetic Vectors; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Structure, Tertiary; Pyruvate Decarboxylase; Pyruvates; Saccharomyces cerevisiae; Substrate Specificity | 1998 |
Cluster-iron substitution is related to structural and functional features of adrenodoxin mutants and to their redox states.
Topics: Adrenodoxin; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Cadmium; Cysteine; Drug Stability; Electron Spin Resonance Spectroscopy; Histidine; Iron; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Protein Conformation; Protein Denaturation; Recombinant Proteins; Thermodynamics; Zinc | 1998 |
Identification of histidine residues in the sugar binding site of snake gourd (Trichosanthes anguina) seed lectin.
Topics: Binding Sites; Cysteine; Galactose; Histidine; Imidazoles; Lectins; Lysine; Plant Lectins; Plant Proteins; Seeds; Tryptophan; Tyrosine | 1998 |
The aggregation in human lens proteins blocks the scavenging of UVA-generated singlet oxygen by ascorbic acid and glutathione.
Topics: Aging; Antioxidants; Ascorbic Acid; Crystallins; Cysteine; Fluorescence; Free Radical Scavengers; Glutathione; Histidine; Humans; Peroxides; Photolysis; Protein Conformation; Protein Denaturation; Reactive Oxygen Species; Sodium Azide; Tryptophan; Ultraviolet Rays; Urea | 1998 |
[Inactivation of chlorhexidine for in vitro testing of disinfectants].
Topics: Anti-Infective Agents, Local; Chlorhexidine; Cysteine; Enterococcus faecium; Histidine; Indicators and Reagents; Microbial Sensitivity Tests; Polysorbates; Saponins | 1998 |
HFE codon 63/282 (H63D/C282Y) dimorphism in German patients with genetic hemochromatosis.
Topics: Aspartic Acid; Codon; Cysteine; Female; Genotype; Germany; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Male; Membrane Proteins; Point Mutation; Polymorphism, Genetic; Tyrosine | 1998 |
Location of a high affinity Zn2+ binding site in the channel of alpha1beta1 gamma-aminobutyric acidA receptors.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Cysteine; Histidine; Molecular Sequence Data; Rats; Receptors, GABA-A; Sequence Homology, Amino Acid; Zinc | 1998 |
The Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity. Cysteine 866 and histidine 881 are essential for enzyme activity.
Topics: Amides; Animals; Bacterial Toxins; Base Sequence; Cloning, Molecular; Cysteine; Cytotoxins; DNA Primers; Escherichia coli Proteins; GTP Phosphohydrolases; GTP-Binding Proteins; Guinea Pigs; Histidine; Liver; Protein Glutamine gamma Glutamyltransferase 2; rhoA GTP-Binding Protein; Structure-Activity Relationship; Transglutaminases | 1998 |
Construction of a family of Cys2His2 zinc binding sites in the hydrophobic core of thioredoxin by structure-based design.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Cobalt; Cysteine; Histidine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Engineering; Protein Folding; Protein Structure, Tertiary; Structure-Activity Relationship; Thioredoxins; Zinc | 1998 |
Transmembrane topography of subunit a in the Escherichia coli F1F0 ATP synthase.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Cell Membrane; Cysteine; Escherichia coli; Glutamine; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Proton-Translocating ATPases; Restriction Mapping; Serine; Spectrometry, Fluorescence; Sulfhydryl Reagents; Surface Properties | 1998 |
delta-Aminolevulinate dehydratase inhibition by ascorbic acid is mediated by an oxidation system existing in the hepatic supernatant.
Topics: Animals; Ascorbic Acid; Binding Sites; Cysteine; Dithiothreitol; Edetic Acid; Enzyme Inhibitors; Free Radical Scavengers; Glutathione; Histidine; Liver; Mannitol; NAD; Oxidation-Reduction; Porphobilinogen Synthase; Rats; Sulfhydryl Compounds; Superoxide Dismutase | 1998 |
Alteration of zif268 zinc-finger motifs gives rise to non-native zinc-co-ordination sites but preserves wild-type DNA recognition.
Topics: Amino Acid Sequence; Amino Acid Substitution; Consensus Sequence; Cysteine; DNA; DNA-Binding Proteins; Escherichia coli; Glutathione Transferase; Histidine; Methylation; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Protein Binding; Recombinant Fusion Proteins; Transcription Factors; Zinc Fingers | 1998 |
Cooperation between the RING + B1-B2 and coiled-coil domains of PML is necessary for its effects on cell survival.
Topics: 3T3 Cells; Animals; Apoptosis; Binding Sites; Cell Division; Cell Line, Transformed; Cell Survival; Cysteine; Cytoplasm; HeLa Cells; Histidine; Humans; Isomerism; Mice; Mutagenesis; Neoplasm Proteins; Nuclear Proteins; Promyelocytic Leukemia Protein; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins; Zinc Fingers | 1998 |
A carboxyl-terminal Cys2/His2-type zinc-finger motif in DNA primase influences DNA content in Synechococcus PCC 7942.
Topics: Base Sequence; Cadmium; Chromosomes, Bacterial; Cyanobacteria; Cysteine; DNA Primase; DNA, Bacterial; Histidine; Molecular Sequence Data; Protein Binding; Zinc; Zinc Fingers | 1998 |
Selective inactivation of butyrylcholinesterase with metal chelators suggests there is more than one metal binding site.
Topics: Binding Sites; Butyrylcholinesterase; Catalysis; Chelating Agents; Cholinesterase Inhibitors; Chromatography, Gel; Cysteine; Dextrans; Edetic Acid; Ethylenediamines; Histidine; Humans; Metals; Phenanthrolines; Spectrophotometry, Atomic; Time Factors; Zinc | 1998 |
Mutations in HFE, the hemochromatosis candidate gene, in patients with NIDDM.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Diabetes Mellitus, Type 2; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Major Histocompatibility Complex; Membrane Proteins; Point Mutation; Reference Values; Tyrosine | 1998 |
Chemical modification of barley root oxalate oxidase shows the presence of a lysine, a carboxylate, and disulfides, essential for enzyme activity.
Topics: Arginine; Carboxylic Acids; Cysteine; Disulfides; Enzyme Activation; Histidine; Hordeum; Lysine; Metals; Oxidoreductases; Plant Roots; Protein Binding; Tyrosine | 1998 |
Pore stoichiometry of a voltage-gated chloride channel.
Topics: Cadmium; Cell Line; Chloride Channels; Cysteine; Electrochemistry; Histidine; Humans; Ion Channel Gating; Mesylates; Molecular Conformation; Muscle Proteins; Mutagenesis, Site-Directed; Phenanthrolines; Sulfhydryl Compounds | 1998 |
Frequency of the HFE C282Y and H63D mutations in distinct ethnic groups living in Spain.
Topics: Alleles; Aspartic Acid; Cysteine; Ethnicity; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Membrane Proteins; Mutation; Roma; Spain; Tyrosine | 1998 |
The relationship between plasma homocysteine and amino acid concentrations in patients with end-stage renal disease.
Topics: Adult; Aged; Amino Acids; Amino Acids, Branched-Chain; Amino Acids, Essential; Cross-Sectional Studies; Cysteine; Female; Histidine; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methionine; Middle Aged; Reference Values | 1998 |
Human serum, cysteine and histidine inhibit the oxidation of low density lipoprotein less at acidic pH.
Topics: Alanine; Antioxidants; Blood; Copper; Cysteine; Extracellular Space; Histidine; Humans; Hydrogen-Ion Concentration; Lipoproteins, LDL; Oxidation-Reduction | 1998 |
Direct voltammetric observation of redox driven changes in axial coordination and intramolecular rearrangement of the phenylalanine-82-histidine variant of yeast iso-1-cytochrome c.
Topics: Amino Acid Substitution; Animals; Cysteine; Cytochrome c Group; Cytochromes c; Electrochemistry; Histidine; Horses; Imidazoles; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine | 1998 |
Use of a novel histidyl modifier to probe for residues on Tris-treated photosystem II membrane fragments that may bind functional manganese.
Topics: 2,6-Dichloroindophenol; Binding Sites; Cysteine; Diphenylcarbazide; Histidine; Intracellular Membranes; Ligands; Magnesium Chloride; Manganese; Oxidation-Reduction; Photochemistry; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Platinum Compounds; Protein Binding; Spinacia oleracea; Tromethamine | 1998 |
Exploring a channel to the active site of copper/topaquinone-containing phenylethylamine oxidase by chemical modification and site-specific mutagenesis.
Topics: 4-Chloro-7-nitrobenzofurazan; Amine Oxidase (Copper-Containing); Amino Acid Sequence; Apoenzymes; Binding Sites; Copper; Cysteine; Dihydroxyphenylalanine; Dithionitrobenzoic Acid; Fluorescent Dyes; Histidine; Holoenzymes; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Substrate Specificity | 1998 |
Identification of subunit interfaces of glycerol dehydrogenase from Bacillus stearothermophilus.
Topics: Amino Acid Substitution; Cysteine; Endopeptidases; Geobacillus stearothermophilus; Histidine; Macromolecular Substances; Mutagenesis, Site-Directed; Protein Structure, Secondary; Recombinant Proteins; Substrate Specificity; Sugar Alcohol Dehydrogenases | 1998 |
The intramolecular electron transfer between copper sites of nitrite reductase: a comparison with ascorbate oxidase.
Topics: Alcaligenes; Ascorbate Oxidase; Binding Sites; Calorimetry; Copper; Crystallography, X-Ray; Cysteine; Electron Transport; Histidine; Kinetics; Nitrite Reductases; Oxidation-Reduction; Thermodynamics | 1998 |
Identification of a histidine acid phosphatase (phyA)-like gene in Arabidopsis thaliana.
Topics: Acid Phosphatase; Amino Acid Sequence; Arabidopsis; Binding Sites; Conserved Sequence; Cysteine; Genes, Plant; Glycosylation; Histidine; Molecular Sequence Data; Sequence Homology, Amino Acid | 1998 |
Free radicals as potential mediators of metal-allergy: Ni2+- and Co2+-mediated free radical generation.
Topics: Acetylcysteine; Adult; Ascorbic Acid; Carnosine; Cells, Cultured; Cobalt; Cysteine; Dermatitis, Allergic Contact; Electron Spin Resonance Spectroscopy; Female; Free Radical Scavengers; Free Radicals; Glutathione; Histidine; Humans; Hydrogen Peroxide; Middle Aged; Monocytes; Nickel | 1998 |
DNA polymerase III of Gram-positive eubacteria is a zinc metalloprotein conserving an essential finger-like domain.
Topics: Amino Acid Sequence; Bacillus subtilis; Binding Sites; Catalysis; Conserved Sequence; Cysteine; DNA Polymerase III; Electrons; Gram-Positive Bacteria; Histidine; Iron; Metalloendopeptidases; Methyl Methanesulfonate; Molecular Sequence Data; Point Mutation; Protein Structure, Tertiary; Recombinant Proteins; Zinc Fingers; Zinc Radioisotopes | 1998 |
[New approach to the study of interaction of amino acid side groups with aryl azides].
Topics: Amino Acids; Azides; Cystamine; Cysteine; Diamines; Electrophoresis, Polyacrylamide Gel; Histamine; Histidine; Imidazoles; Lysine; Models, Molecular; Oligonucleotides; Ultraviolet Rays | 1998 |
Autocatalytic activation of human legumain at aspartic acid residues.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Blotting, Western; Catalytic Domain; Cell Line; Cysteine; Cysteine Endopeptidases; Enzyme Activation; Expressed Sequence Tags; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Plant Proteins; Recombinant Fusion Proteins; Sequence Alignment; Substrate Specificity | 1998 |
Partial characterization of the active site human platelet cAMP phosphodiesterase, PDE3A, by site-directed mutagenesis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amino Acid Sequence; Animals; Binding Sites; Blood Platelets; Catalysis; Cattle; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cysteine; Histidine; Humans; Kinetics; Milrinone; Molecular Sequence Data; Mutagenesis, Site-Directed | 1998 |
The identification of metal-binding ligand residues in metalloproteins using nuclear magnetic resonance spectroscopy.
Topics: Bacteroides fragilis; beta-Lactamases; Binding Sites; Cysteine; Edetic Acid; Histidine; Magnetic Resonance Spectroscopy; Molecular Weight; Nitrogen Isotopes; Recombinant Proteins; Zinc | 1998 |
Prevalence of the Cys282Tyr and His63Asp HFE gene mutations in Spanish patients with hereditary hemochromatosis and in controls.
Topics: Adult; Aged; Cysteine; Female; Genes, MHC Class I; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Male; Membrane Proteins; Middle Aged; Mutation; Spain | 1998 |
X-ray crystal structure of the Fe-only hydrogenase (CpI) from Clostridium pasteurianum to 1.8 angstrom resolution.
Topics: Amino Acid Sequence; Binding Sites; Carbon Monoxide; Catalytic Domain; Clostridium; Crystallography, X-Ray; Cyanides; Cysteine; Histidine; Hydrogen; Hydrogenase; Iron; Ligands; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protons; Sulfur | 1998 |
Influence of chemical modification of cysteine and histidine side chains upon subunit reassembly of alpha crystallin.
Topics: Chromatography, Gel; Circular Dichroism; Crystallins; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Histidine; Protein Conformation; Protein Folding; Structure-Activity Relationship | 1998 |
Are His63Asp or Cys282Tyr HFE mutations associated with porphyria cutanea tarda? Data of patients from central and southern Italy.
Topics: Asparagine; Cysteine; Histidine; Humans; Italy; Point Mutation; Porphyria Cutanea Tarda; Tyrosine | 1998 |
Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2.
Topics: Amino Acid Sequence; Aminopeptidases; Animals; Anti-Bacterial Agents; Catalytic Domain; Cell Division; Cell Line; Cyclohexanes; Cysteine; Endothelium, Vascular; Fatty Acids, Unsaturated; Histidine; Humans; Metalloendopeptidases; Mutagenesis, Site-Directed; Neovascularization, Pathologic; Recombinant Proteins; Sesquiterpenes; Spodoptera; Transfection | 1998 |
Metal chelating properties of adenylate kinase from Paracoccus denitrificans.
Topics: Adenylate Kinase; Amino Acid Sequence; Base Sequence; Chelating Agents; Cloning, Molecular; Cysteine; Dimerization; Dithionitrobenzoic Acid; Enzyme Stability; Escherichia coli; Histidine; Iron; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Paracoccus denitrificans; Phosphorylation; Protein Denaturation; Recombinant Proteins; Sequence Homology, Amino Acid; Titrimetry; Trypsin; Zinc | 1998 |
Solution structure of the His12 --> Cys mutant of the N-terminal zinc binding domain of HIV-1 integrase complexed to cadmium.
Topics: Binding Sites; Cadmium; Cysteine; Histidine; HIV Integrase; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Protein Conformation; Zinc | 1998 |
Introduction of histidine analogs leads to enhanced proton transfer in carbonic anhydrase V.
Topics: Animals; Carbonic Anhydrases; Catalysis; Cysteine; Histidine; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Oxygen Isotopes; Protons; Substrate Specificity | 1999 |
Replacement of terminal cysteine with histidine in the metallothionein alpha and beta domains maintains its binding capacity.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cadmium; Circular Dichroism; Cysteine; Escherichia coli; Histidine; Mass Spectrometry; Metallothionein; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Conformation; Recombinant Proteins; Spectrophotometry, Ultraviolet; Zinc | 1999 |
Involvement of essential cysteine and histidine residues in the activity of isolated glutaminase from tumour cells.
Topics: Animals; Binding Sites; Carcinoma, Ehrlich Tumor; Cysteine; Diethyl Pyrocarbonate; Enzyme Inhibitors; Ethylmaleimide; Glutaminase; Histidine; Hydrogen-Ion Concentration; Intracellular Membranes | 1998 |
A structure-based mechanism for copper-zinc superoxide dismutase.
Topics: Amino Acid Substitution; Animals; Cattle; Copper; Crystallography, X-Ray; Cysteine; Histidine; Humans; Models, Molecular; Oxidation-Reduction; Oxygen; Saccharomyces cerevisiae; Structure-Activity Relationship; Superoxide Dismutase; Xenopus laevis; Zinc | 1999 |
Role of cysteine-82 in the catalytic mechanism of human S-adenosylmethionine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Catalysis; Cysteine; Enzyme Activation; Enzyme Inhibitors; Histidine; Humans; Hydrogen-Ion Concentration; Iodoacetic Acid; Kinetics; Mutagenesis, Site-Directed; Recombinant Fusion Proteins; S-Adenosylmethionine; Substrate Specificity | 1999 |
Metal-catalyzed oxidation of phenylalanine-sensitive 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Escherichia coli: inactivation and destabilization by oxidation of active-site cysteines.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Anaerobiosis; Binding Sites; Catalase; Cations, Divalent; Copper Sulfate; Cysteine; Enzyme Stability; Escherichia coli; Histidine; Kinetics; Models, Chemical; Oxidation-Reduction; Peptide Mapping | 1999 |
Identification of two important heme site residues (cysteine 75 and histidine 77) in CooA, the CO-sensing transcription factor of Rhodospirillum rubrum.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Carbon Monoxide; Cysteine; Escherichia coli; Ferric Compounds; Ferrous Compounds; Heme; Hemeproteins; Histidine; Ligands; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Rhodospirillum rubrum; Trans-Activators | 1999 |
Rate-determining step of Escherichia coli alkaline phosphatase altered by the removal of a positive charge at the active center.
Topics: Alanine; Alkaline Phosphatase; Binding Sites; Cysteine; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Magnesium; Models, Molecular; Mutagenesis, Site-Directed; Phosphates | 1999 |
HlyC, the internal protein acyltransferase that activates hemolysin toxin: role of conserved histidine, serine, and cysteine residues in enzymatic activity as probed by chemical modification and site-directed mutagenesis.
Topics: Acetyltransferases; Acyltransferases; Amino Acid Sequence; Bacterial Proteins; Bacterial Toxins; Catalysis; Conserved Sequence; Cysteine; Enzyme Activation; Escherichia coli; Escherichia coli Proteins; Hemolysin Proteins; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Repetitive Sequences, Amino Acid; Serine | 1999 |
Analysis of zinc binding sites in protein crystal structures.
Topics: Aspartic Acid; Binding Sites; Catalysis; Chlorine; Crystallography, X-Ray; Cysteine; Databases, Factual; Glutamine; Histidine; Models, Molecular; Molecular Conformation; Nitrogen; Oxygen; Protein Binding; Sulfur; Zinc | 1998 |
Replacement of the proximal histidine iron ligand by a cysteine or tyrosine converts heme oxygenase to an oxidase.
Topics: Amino Acid Substitution; Catalysis; Cysteine; Electron Transport; Ferric Compounds; Ferrous Compounds; Heme; Heme Oxygenase (Decyclizing); Histidine; Humans; Iron; Ligands; Mutagenesis; Oxidation-Reduction; Oxidoreductases; Peroxides; Spectrum Analysis, Raman; Tyrosine | 1999 |
Identification of three cysteines as targets for the Zn2+ blockade of the human skeletal muscle chloride channel.
Topics: Cell Line; Chloride Channels; Cysteine; Diethyl Pyrocarbonate; Histidine; Humans; Hydrogen-Ion Concentration; Muscle Proteins; Muscle, Skeletal; Mutagenesis, Site-Directed; Zinc | 1999 |
Site-directed mutagenesis of the cysteine ligands to the [4Fe-4S] cluster of Escherichia coli MutY.
Topics: Alanine; Cell Fractionation; Cysteine; DNA Glycosylases; DNA Repair; DNA, Bacterial; Enzyme Activation; Enzyme Stability; Escherichia coli; Histidine; Iron-Sulfur Proteins; Ligands; Models, Molecular; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Protein Binding; Recombinant Proteins; Serine | 1999 |
The CuA domain of Thermus thermophilus ba3-type cytochrome c oxidase at 1.6 A resolution.
Topics: Amino Acid Sequence; Azurin; Binding Sites; Conserved Sequence; Copper; Crystallization; Crystallography, X-Ray; Cysteine; Cytochrome b Group; Electron Transport Complex IV; Histidine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Folding; Protein Structure, Secondary; Sequence Alignment; Sulfur; Thermus thermophilus; Zinc | 1999 |
Proximity between Glu126 and Arg144 in the lactose permease of Escherichia coli.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Histidine; Manganese; Membrane Transport Proteins; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Spectrometry, Fluorescence; Spin Labels; Symporters | 1999 |
The gag domains required for avian retroviral RNA encapsidation determined by using two independent assays.
Topics: Animals; Avian Sarcoma Viruses; Base Sequence; Binding Sites; Birds; Capsid; Cysteine; Gene Products, gag; Genome, Viral; Histidine; Molecular Sequence Data; Mutagenesis; Nucleic Acid Conformation; RNA, Viral; Viral Matrix Proteins; Virus Assembly | 1999 |
Crystal structure of human quinone reductase type 2, a metalloflavoprotein.
Topics: Animals; Binding Sites; Copper; Crystallization; Crystallography, X-Ray; Cysteine; Flavin-Adenine Dinucleotide; Flavoproteins; Histidine; Humans; Metalloproteins; Mice; NAD(P)H Dehydrogenase (Quinone); Rats; Solutions; Vitamin K | 1999 |
A histidine thiol 100 kDa, tetrameric acid phosphatase from lentil, Lens esculenta, seeds with the characteristics of protein tyrosine phosphatases.
Topics: Adenosine Monophosphate; Aniline Compounds; Binding Sites; Chromatography, Liquid; Cysteine; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Fabaceae; Histidine; Kinetics; Molecular Weight; Organophosphorus Compounds; Plants, Medicinal; Protein Conformation; Protein Tyrosine Phosphatases; Seeds; Substrate Specificity | 1999 |
Engineering cytochrome c peroxidase into cytochrome P450: a proximal effect on heme-thiolate ligation.
Topics: Aspartic Acid; Circular Dichroism; Cysteine; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome-c Peroxidase; Cytochromes c; Electron Spin Resonance Spectroscopy; Escherichia coli; Ferric Compounds; Heme; Histidine; Imidazoles; Leucine; Ligands; Mutagenesis, Site-Directed; Protein Engineering; Spectrophotometry, Ultraviolet | 1999 |
Reduction of adenosine-5'-phosphosulfate instead of 3'-phosphoadenosine-5'-phosphosulfate in cysteine biosynthesis by Rhizobium meliloti and other members of the family Rhizobiaceae.
Topics: Adenosine Phosphosulfate; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; Cysteine; DNA, Bacterial; Histidine; Molecular Sequence Data; Multienzyme Complexes; Oxidation-Reduction; Phosphoadenosine Phosphosulfate; Phosphotransferases (Alcohol Group Acceptor); Recombinant Fusion Proteins; Rhizobiaceae; Sequence Homology, Amino Acid; Sinorhizobium meliloti; Sulfites; Sulfotransferases | 1999 |
Mutants that alter the covalent structure of catalase hydroperoxidase II from Escherichia coli.
Topics: Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Catalase; Crystallography, X-Ray; Cysteine; Escherichia coli; Genetic Variation; Glutamic Acid; Heme; Histidine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Conformation; Recombinant Proteins; Restriction Mapping | 1999 |
Significance of metal ions in galactose-1-phosphate uridylyltransferase: an essential structural zinc and a nonessential structural iron.
Topics: Asparagine; Binding Sites; Chromatography, Affinity; Circular Dichroism; Cysteine; Dialysis; Edetic Acid; Enzyme Activation; Escherichia coli; Histidine; Iron; Kinetics; Ligands; Mutagenesis, Site-Directed; Phenanthrolines; Recombinant Proteins; Serine; Structure-Activity Relationship; Triazines; UDPglucose-Hexose-1-Phosphate Uridylyltransferase; Uridine Diphosphate Glucose; Zinc | 1999 |
Replacement of the proximal heme thiolate ligand in chloroperoxidase with a histidine residue.
Topics: Amino Acid Substitution; Chloride Peroxidase; Cysteine; Epoxy Compounds; Escherichia coli; Genetic Vectors; Heme; Histidine; Mutagenesis, Site-Directed | 1999 |
Posttranslational heterocyclization of cysteine and serine residues in the antibiotic microcin B17: distributivity and directionality.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Bacteriocins; Cysteine; Histidine; Hydrolysis; Kinetics; Mass Spectrometry; Molecular Sequence Data; Multienzyme Complexes; Protein Precursors; Protein Processing, Post-Translational; Protein Sorting Signals; Recombinant Fusion Proteins; Serine; Substrate Specificity | 1999 |
In vitro and in vivo evaluation of bidentate, water-soluble phosphine ligands as anchor groups for the organometallic fac-[99mTc(CO)3]+-core.
Topics: Animals; Cysteine; Histidine; Humans; Indicators and Reagents; Metabolic Clearance Rate; Mice; Molecular Structure; Organotechnetium Compounds; Radiopharmaceuticals; Serum Albumin; Technetium; Tissue Distribution | 1999 |
The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Topics: Apoenzymes; Asparagine; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Crystallography, X-Ray; Cysteine; Escherichia coli; Glutamine; Histidine; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Peptide Fragments; Serine; Stereoisomerism | 1999 |
The mycotoxin patulin induces intra- and intermolecular protein crosslinks in vitro involving cysteine, lysine, and histidine side chains, and alpha-amino groups.
Topics: Animals; Cattle; Chickens; Cross-Linking Reagents; Cysteine; Dansyl Compounds; Female; Fluorescent Dyes; Glutathione; Histidine; Lysine; Muramidase; Patulin; Protein Conformation; Protein Structure, Tertiary; Serum Albumin, Bovine; Sulfhydryl Compounds; Tubulin | 1999 |
Coupled oxidation of heme covalently attached to cytochrome b562 yields a novel biliprotein.
Topics: Arginine; Bacterial Proteins; Biliverdine; Cloning, Molecular; Cysteine; Cytochrome b Group; Escherichia coli; Escherichia coli Proteins; Heme; Histidine; Hydrolysis; Methionine; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Pyrroles; Tetrapyrroles | 1999 |
[Demonstration of HFE polymorphism in German patients with hereditary hemochromatosis].
Topics: Amino Acid Sequence; Asparagine; Chromosomes, Human, Pair 6; Codon; Cysteine; Germany; Hemochromatosis; Heterozygote; Histidine; HLA Antigens; Homozygote; Humans; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Tyrosine | 1999 |
DNA-induced alpha-helix capping in conserved linker sequences is a determinant of binding affinity in Cys(2)-His(2) zinc fingers.
Topics: Amino Acid Sequence; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Cysteine; DNA; DNA-Binding Proteins; Histidine; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; Sequence Alignment; Sequence Homology, Amino Acid; Transcription Factor TFIIIA; Transcription Factors; WT1 Proteins; Zinc Fingers | 2000 |
The solution structure of ribosomal protein L36 from Thermus thermophilus reveals a zinc-ribbon-like fold.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Conserved Sequence; Cysteine; Histidine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; Protein Structure, Tertiary; Ribosomal Proteins; RNA, Ribosomal; Sequence Alignment; Solutions; Static Electricity; Thermus thermophilus; Zinc | 2000 |
A class of zinc fingers involved in protein-protein interactions biophysical characterization of CCHC fingers from fog and U-shaped.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cysteine; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Erythroid-Specific DNA-Binding Factors; Histidine; Hydrogen-Ion Concentration; Insect Proteins; Molecular Sequence Data; Mutation; Nuclear Proteins; Protein Binding; Protein Folding; Protein Structure, Secondary; Recombinant Fusion Proteins; Spectrum Analysis; Temperature; Thermodynamics; Transcription Factors; Two-Hybrid System Techniques; Zinc; Zinc Fingers | 2000 |
A critical histidine in the vesicular acetylcholine transporter.
Topics: Animals; Binding Sites; Carrier Proteins; Cysteine; Diethyl Pyrocarbonate; Electric Organ; Histidine; Hydrogen-Ion Concentration; Membrane Transport Proteins; Neuromuscular Depolarizing Agents; Piperidines; Protons; Synaptic Vesicles; Torpedo; Tritium; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 2000 |
Identification of specific histidine residues and the carboxyl terminus are essential for serotonin N-acetyltransferase enzymatic activity.
Topics: Acetyl Coenzyme A; Amino Acid Sequence; Animals; Arylamine N-Acetyltransferase; Conserved Sequence; Cysteine; Enzyme Stability; Gene Deletion; Histidine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Sequence Homology, Amino Acid | 2000 |
Clinical characteristics of type 2 diabetes in patients with mutations of HFE.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Diabetes Mellitus, Type 2; Female; Ferritins; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Insulin Resistance; Iron; Major Histocompatibility Complex; Male; Membrane Proteins; Middle Aged; Point Mutation; Transferrin; Tyrosine | 2000 |
Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly.
Topics: Allylglycine; Bacterial Proteins; Binding Sites; Catalysis; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Dimerization; Histidine; Hydrogen-Ion Concentration; Iron-Sulfur Proteins; Lyases; Lysine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Structure, Secondary; Pyridoxal Phosphate; Selenomethionine; Spectrophotometry; Sulfur; Thermotoga maritima; Transaminases | 2000 |
Active site determination of Gpi8p, a caspase-related enzyme required for glycosylphosphatidylinositol anchor addition to proteins.
Topics: Alleles; Amino Acid Sequence; Aminoacyltransferases; Binding Sites; Caspases; Cell Adhesion Molecules; Cell Division; Cysteine; Fungal Proteins; Gene Expression Regulation, Fungal; Genetic Complementation Test; Glycosylphosphatidylinositols; Histidine; Humans; Membrane Glycoproteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenotype; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2000 |
Molecular mapping of statherin- and histatin-binding domains in human salivary mucin MG1 (MUC5B) by the yeast two-hybrid system.
Topics: Amylases; Blotting, Western; Bronchi; Cysteine; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Histidine; Humans; Molecular Weight; Mucin-5B; Mucins; Peptides; Phosphoproteins; Proline; Proline-Rich Protein Domains; Protein Binding; Protein Structure, Tertiary; Proteins; Salivary Proteins and Peptides; Sublingual Gland; Submandibular Gland; Tandem Repeat Sequences; Trachea; Yeasts | 2000 |
Investigation of spectroscopic intermediates during copper-binding and TPQ formation in wild-type and active-site mutants of a copper-containing amine oxidase from yeast.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Binding Sites; Coenzymes; Copper; Cysteine; Dihydroxyphenylalanine; Glutamic Acid; Glutamine; Histidine; Mutagenesis, Site-Directed; Oxygen Consumption; Pichia; Recombinant Proteins; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet | 2000 |
Interaction of a novel cysteine and histidine-rich cytoplasmic protein with galectin-3 in a carbohydrate-independent manner.
Topics: 3T3 Cells; Amino Acid Motifs; Amino Acid Sequence; Animals; Antigens, Differentiation; Binding Sites; Carbohydrate Metabolism; Cell Nucleus; Cloning, Molecular; Conserved Sequence; Cysteine; Cytoplasm; Galectin 3; Histidine; Humans; Mice; Microscopy, Fluorescence; Molecular Sequence Data; Peptide Fragments; Precipitin Tests; Protein Binding; Proteins; RNA, Messenger; Sequence Alignment; Two-Hybrid System Techniques | 2000 |
Genetic analysis of a potential zinc-binding domain of the adenovirus E4 34k protein.
Topics: Adenoviridae; Adenovirus E4 Proteins; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Cell Line; Conserved Sequence; Cysteine; Histidine; Humans; Mammals; Molecular Sequence Data; Molecular Weight; Open Reading Frames; Osteosarcoma; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Spodoptera; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Zinc | 2000 |
The transactivation domain within cysteine/histidine-rich region 1 of CBP comprises two novel zinc-binding modules.
Topics: Amino Acid Sequence; Animals; Arabidopsis; Binding Sites; Caenorhabditis elegans; Circular Dichroism; CREB-Binding Protein; Cysteine; Drosophila melanogaster; Histidine; Humans; Mice; Molecular Sequence Data; Nicotiana; Nuclear Proteins; Plants, Toxic; Protein Folding; Sequence Alignment; Sequence Homology, Amino Acid; Trans-Activators; Transcriptional Activation; Zinc; Zinc Fingers | 2000 |
Evidence for tryptophan in proximity to histidine and cysteine as essential to the active site of an alkaline protease.
Topics: Affinity Labels; Binding Sites; Chromatography, DEAE-Cellulose; Conidiobolus; Cysteine; Endopeptidases; Energy Transfer; Fluoresceins; Guanidine; Histidine; Kinetics; Spectrometry, Fluorescence; Tryptophan; Ultrafiltration | 2000 |
Probing the extracellular release site of the plasma membrane calcium pump.
Topics: Binding Sites; Cadmium; Calcium Signaling; Calcium-Transporting ATPases; Cysteine; Erythrocyte Membrane; Ethyl Methanesulfonate; Extracellular Space; Histidine; Humans; In Vitro Techniques; Ion Transport; Membrane Potentials; Mesylates; Models, Biological; Protons | 2000 |
The Cys(3)-His(1) motif of the respiratory syncytial virus M2-1 protein is essential for protein function.
Topics: Amino Acid Motifs; Amino Acid Sequence; Cysteine; Electrophoresis, Polyacrylamide Gel; Histidine; HN Protein; Humans; Molecular Sequence Data; Mutagenesis; Nucleocapsid Proteins; Phosphorylation; Protein Isoforms; Respiratory Syncytial Virus, Human; Sodium Dodecyl Sulfate; Tumor Cells, Cultured; Viral Envelope Proteins; Viral Proteins | 2000 |
Structure of arylamine N-acetyltransferase reveals a catalytic triad.
Topics: Acetanilides; Amino Acid Sequence; Arylamine N-Acetyltransferase; Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Histidine; Models, Molecular; Molecular Sequence Data; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Salmonella typhimurium; Sequence Alignment; Structure-Activity Relationship | 2000 |
Structural characterization of the cysteine-rich domain of TFIIH p44 subunit.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cysteine; DNA Helicases; Histidine; Humans; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutation; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Kinase C; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; Sequence Alignment; Structure-Activity Relationship; Transcription Factor TFIIH; Transcription Factors; Transcription Factors, TFII; Transcription, Genetic; Zinc; Zinc Fingers | 2000 |
Copper(2+) binding to the surface residue cysteine 111 of His46Arg human copper-zinc superoxide dismutase, a familial amyotrophic lateral sclerosis mutant.
Topics: Amyotrophic Lateral Sclerosis; Arginine; Binding, Competitive; Cobalt; Copper; Cysteine; Histidine; Humans; Models, Molecular; Mutation; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Silver; Spectrum Analysis, Raman; Superoxide Dismutase; Titrimetry | 2000 |
MDP-1: A novel eukaryotic magnesium-dependent phosphatase.
Topics: Amino Acid Sequence; Animals; Catalysis; Cations; Chromatography, Affinity; Cloning, Molecular; Cysteine; Enzyme Inhibitors; Histidine; Hydrogen-Ion Concentration; Magnesium; Mice; Molecular Sequence Data; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Phosphatase 2C; Rabbits; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Substrate Specificity | 2000 |
Role of the histidine residues of visna virus nucleocapsid protein in metal ion and DNA binding.
Topics: Alkylation; Amino Acid Sequence; Animals; Binding Sites; Cysteine; DNA, Viral; Histidine; In Vitro Techniques; Kinetics; Metals; Nucleocapsid; Sheep; Spectrometry, Fluorescence; Spectrophotometry; Visna-maedi virus; Zinc Fingers | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Identification of copper ligands in Aspergillus oryzae tyrosinase by site-directed mutagenesis.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspergillus oryzae; Binding Sites; Blotting, Western; Catalysis; Circular Dichroism; Copper; Cysteine; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Ligands; Molecular Sequence Data; Monophenol Monooxygenase; Mutagenesis, Site-Directed; Nitrogen; Oxygenases; Peroxidases; Protein Binding; Recombinant Fusion Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Spectrophotometry, Atomic; Sulfur; Thioredoxins | 2000 |
Functional analysis of the active site of a metallo-beta-lactamase proliferating in Japan.
Topics: Anti-Bacterial Agents; Apoenzymes; Aspartic Acid; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Binding Sites; Binding, Competitive; Cysteine; Dose-Response Relationship, Drug; Escherichia coli; Histidine; Humans; Japan; Kinetics; Klebsiella pneumoniae; Ligands; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Zinc | 2000 |
Evidence for catalytic cysteine-histidine dyad in chalcone synthase.
Topics: Acyltransferases; Amino Acid Substitution; Binding Sites; Catalysis; Cysteine; Diethyl Pyrocarbonate; Enzyme Inhibitors; Escherichia coli; Flavanones; Flavonoids; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Malonyl Coenzyme A; Mutagenesis, Site-Directed; Plants; Recombinant Fusion Proteins; Resveratrol; Stilbenes | 2000 |
Sensitive monitoring of the dynamics of a membrane-bound transport protein by tryptophan phosphorescence spectroscopy.
Topics: Binding Sites; Biological Transport; Carrier Proteins; Cysteine; Escherichia coli; Escherichia coli Proteins; Freezing; Glass; Histidine; Luminescent Measurements; Mannitol; Membrane Proteins; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Solutions; Spectrometry, Fluorescence; Thermodynamics; Tryptophan | 2000 |
Mechanism of chalcone synthase. pKa of the catalytic cysteine and the role of the conserved histidine in a plant polyketide synthase.
Topics: Acyltransferases; Alkylating Agents; Anions; Binding Sites; Carboxy-Lyases; Catalysis; Conserved Sequence; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamine; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics; Models, Chemical; Models, Molecular; Protein Binding; Time Factors | 2000 |
Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP.
Topics: Adenovirus E1A Proteins; Amino Acid Sequence; Animals; Apoproteins; Binding Sites; Circular Dichroism; CREB-Binding Protein; Cysteine; Histidine; Ligands; Mice; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Protein Binding; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Solutions; Thermodynamics; Trans-Activators; Transcriptional Activation; Tumor Suppressor Protein p53; Zinc; Zinc Fingers | 2000 |
Structure of a (Cys3His) zinc ribbon, a ubiquitous motif in archaeal and eucaryal transcription.
Topics: Amino Acid Motifs; Amino Acid Sequence; Archaea; Cysteine; Eukaryotic Cells; Histidine; Humans; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; Sequence Homology, Amino Acid; Transcription Factor TFIIB; Transcription Factors; Transcription, Genetic; Zinc | 2000 |
Examining the zinc binding site of the amyloid-beta peptide.
Topics: Amino Acid Substitution; Amyloid beta-Peptides; Binding Sites; Circular Dichroism; Cysteine; Histidine; Microfibrils; Molecular Sequence Data; Peptide Fragments; Protein Structure, Secondary; Zinc | 2000 |
Changing the heme ligation in flavocytochrome b2: substitution of histidine-66 by cysteine.
Topics: Amino Acid Substitution; Circular Dichroism; Cysteine; Electron Spin Resonance Spectroscopy; Flavin Mononucleotide; Heme; Histidine; Kinetics; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Mutation; Oxidation-Reduction; Protein Binding; Saccharomyces cerevisiae; Spectrophotometry; Spectrum Analysis, Raman | 2000 |
A histidine residue in the catalytic mechanism distinguishes Vibrio harveyi aldehyde dehydrogenase from other members of the aldehyde dehydrogenase superfamily.
Topics: Acyl Coenzyme A; Acylation; Acyltransferases; Aldehyde Dehydrogenase; Animals; Binding Sites; Catalytic Domain; Cysteine; Enzyme Activation; Esterases; Ethylmaleimide; Histidine; Kinetics; Multigene Family; Mutagenesis, Site-Directed; NADP; Niacinamide; Rats; Sequence Homology, Amino Acid; Thiolester Hydrolases; Vibrio | 2000 |
Zinc release from the CH2C6 zinc finger domain of FILAMENTOUS FLOWER protein from Arabidopsis thaliana induces self-assembly.
Topics: Alanine; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Chelating Agents; Chromatography, Gel; Circular Dichroism; Cysteine; Edetic Acid; Gene Deletion; Genetic Vectors; Glutathione Transferase; Histidine; Leucine; Ligands; Molecular Sequence Data; Mutation; Plant Proteins; Plasmids; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sulfhydryl Compounds; Time Factors; Transcription, Genetic; Zinc; Zinc Fingers | 2001 |
Redox properties and coordination structure of the heme in the co-sensing transcriptional activator CooA.
Topics: Alanine; Bacterial Proteins; Cysteine; Electrochemistry; Escherichia coli Proteins; Fimbriae Proteins; Heme; Histidine; Iron; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Spectrum Analysis, Raman; Transcriptional Activation | 2001 |
Crystal structure of the "cab"-type beta class carbonic anhydrase from the archaeon Methanobacterium thermoautotrophicum.
Topics: Amino Acid Sequence; Archaea; Binding Sites; Carbonic Anhydrases; Crystallography; Cysteine; Histidine; Kinetics; Ligands; Methanobacterium; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protons; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Water; Zinc | 2001 |
Functional characterization of isoschizomeric His-Cys box homing endonucleases from Naegleria.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cysteine; DNA, Protozoan; Endonucleases; Histidine; Introns; Molecular Sequence Data; Mutagenesis, Site-Directed; Naegleria; Open Reading Frames; Sequence Homology, Amino Acid | 2000 |
Monoclonal antibody that binds to the central loop of the Tn10-encoded metal tetracycline/H+ antiporter of Escherichia coli.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antibody Specificity; Antiporters; Bacterial Proteins; Binding Sites, Antibody; Cysteine; Epitopes; Escherichia coli; Histidine; Molecular Sequence Data; Protein Conformation | 2001 |
Two novel mutations (Y141H; C214Y) and previously published mutation (R142W) in the RDS-peripherin gene in autosomal dominant macular dystrophies in Spanish families.
Topics: Amino Acid Substitution; Arginine; Cysteine; Electrophoresis, Polyacrylamide Gel; Eye Proteins; Genes, Dominant; Histidine; Humans; Intermediate Filament Proteins; Macular Degeneration; Membrane Glycoproteins; Mutation, Missense; Nerve Tissue Proteins; Peripherins; Polymerase Chain Reaction; Retinal Degeneration; Tryptophan; Tyrosine | 2001 |
Three pairs of cysteine residues mediate both redox and zn2+ modulation of the nmda receptor.
Topics: Animals; Binding Sites; Cells, Cultured; Cysteine; Dithiothreitol; Dose-Response Relationship, Drug; Drug Synergism; Glycine; Histidine; Mesylates; Mutagenesis, Site-Directed; N-Methylaspartate; Oocytes; Oxidation-Reduction; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Sulfhydryl Reagents; Transfection; Xenopus; Zinc | 2001 |
DNA-protein crosslinks induced by nickel compounds in isolated rat lymphocytes: role of reactive oxygen species and specific amino acids.
Topics: Acetates; Animals; Cross-Linking Reagents; Cysteine; Deferoxamine; DNA; DNA Damage; Dose-Response Relationship, Drug; Free Radical Scavengers; Histidine; Lymphocytes; Magnesium; Nickel; Occupational Exposure; Organometallic Compounds; Oxidative Stress; Proteins; Rats; Reactive Oxygen Species | 2001 |
Proximal cysteine residue is essential for the enzymatic activities of cytochrome P450cam.
Topics: Benzene Derivatives; Camphor; Camphor 5-Monooxygenase; Carbon Monoxide; Catalytic Domain; Cysteine; Ferric Compounds; Ferrous Compounds; Histidine; Ligands; Mutation; Protein Folding; Spectrophotometry | 2001 |
Haemochromatosis: automated detection of the two point mutations in the HFE gene: Cys282Tyr and His63Asp.
Topics: Aspartic Acid; Cysteine; DNA Mutational Analysis; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Membrane Proteins; Mutation; Point Mutation; Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity; Tyrosine | 2000 |
Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase.
Topics: Amino Acid Substitution; Animals; Arginase; Arginine; Binding, Competitive; Catalysis; Crystallography, X-Ray; Cysteine; Enzyme Inhibitors; Histidine; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Ornithine; Rats; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Urea | 2001 |
Specific amino acids moderate the effects on Ni2+ on the testosterone production of mouse leydig cells in vitro.
Topics: Amino Acids; Animals; Cells, Cultured; Chelating Agents; Cysteine; Dose-Response Relationship, Drug; Histidine; Leydig Cells; Male; Mice; Mice, Inbred Strains; Nickel; Radioimmunoassay; Testosterone; Time Factors | 2001 |
Interaction of the ring finger-related U-box motif of a nuclear dot protein with ubiquitin-conjugating enzymes.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Motifs; Amino Acid Sequence; Animals; Antigens, Nuclear; Autoantigens; Blotting, Northern; Carrier Proteins; Cell Line; Cell Nucleus; Cysteine; Cysteine Endopeptidases; HeLa Cells; Histidine; Humans; Immunohistochemistry; Ligases; Mice; Microscopy, Fluorescence; Molecular Sequence Data; Multienzyme Complexes; Nuclear Proteins; Plasmids; Proteasome Endopeptidase Complex; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; RNA; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Two-Hybrid System Techniques; Ubiquitin-Conjugating Enzymes; Ubiquitins | 2001 |
Identification of essential residues in 2',3'-cyclic nucleotide 3'-phosphodiesterase. Chemical modification and site-directed mutagenesis to investigate the role of cysteine and histidine residues in enzymatic activity.
Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Amino Acid Sequence; Animals; Base Sequence; Catalytic Domain; Cysteine; Dithionitrobenzoic Acid; DNA Primers; Enzyme Inhibitors; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoric Diester Hydrolases; Rats; Recombinant Proteins; Sequence Homology, Amino Acid | 2001 |
Structural and functional consequences of inactivation of human glutathione S-transferase P1-1 mediated by the catechol metabolite of equine estrogens, 4-hydroxyequilenin.
Topics: Amino Acid Substitution; Animals; Cysteine; Disulfides; Dithionitrobenzoic Acid; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Equilenin; Estrogens, Catechol; Free Radical Scavengers; Glutathione S-Transferase pi; Glutathione Transferase; Histidine; Horses; Humans; Isoenzymes; Kinetics; Mutagenesis, Site-Directed; Oxidation-Reduction; Recombinant Proteins; Reducing Agents; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfhydryl Reagents; Titrimetry | 2001 |
Eubacterial arylamine N-acetyltransferases - identification and comparison of 18 members of the protein family with conserved active site cysteine, histidine and aspartate residues.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arylamine N-Acetyltransferase; Aspartic Acid; Bacterial Proteins; Blotting, Western; Catalytic Domain; Conserved Sequence; Cysteine; Enterobacteriaceae; Gram-Positive Bacteria; Histidine; Models, Molecular; Molecular Sequence Data; Operon; Polymerase Chain Reaction; Polymorphism, Genetic; Proteobacteria; Sequence Alignment; Substrate Specificity | 2001 |
Solution structure of Methylophilus methylotrophus cytochrome c": insights into the structural basis of haem-ligand detachment.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Cytochrome c Group; Disulfides; Heme; Histidine; Ligands; Methylophilus methylotrophus; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation | 2001 |
Organization of the multiple coenzymes and subunits and role of the covalent flavin link in the complex heterotetrameric sarcosine oxidase.
Topics: Acetates; Alanine; Arthrobacter; Asparagine; Coenzymes; Corynebacterium; Cysteine; Enzyme Stability; Flavin Mononucleotide; Flavins; Gene Expression Regulation, Bacterial; Glycine; Histidine; Macromolecular Substances; Mutagenesis, Site-Directed; Oxidoreductases, N-Demethylating; Pseudomonas; Recombinant Proteins; Sarcosine Oxidase; Sulfites; Valine | 2001 |
Active-site residues of a plant membrane-bound fatty acid elongase beta-ketoacyl-CoA synthase, FAE1 KCS.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyltransferases; Amino Acid Sequence; Arabidopsis; Binding Sites; Cell Membrane; Cysteine; Erucic Acids; Fatty Acid Elongases; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Sequence Alignment | 2001 |
Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase of riboflavin biosynthesis.
Topics: Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Dimerization; Escherichia coli; Glutamic Acid; Histidine; Intramolecular Transferases; Magnesium; Models, Chemical; Models, Molecular; Protein Structure, Secondary; Riboflavin; Riboflavin Synthase | 2001 |
A central functional role for the 49-kDa subunit within the catalytic core of mitochondrial complex I.
Topics: Amino Acid Sequence; Binding Sites; Conserved Sequence; Cysteine; Electron Transport Complex I; Fungal Proteins; Histidine; Hydrogenase; Mitochondria; Models, Chemical; Molecular Sequence Data; Mutation; NADH, NADPH Oxidoreductases; Protein Structure, Tertiary; Protein Subunits; Saccharomycetales; Sequence Homology, Amino Acid; Ubiquinone | 2001 |
Conformation and polarity of the active site of xylanase I from Thermomonospora sp. as deduced by fluorescent chemoaffinity labeling. Site and significance of a histidine residue.
Topics: Actinomycetales; Affinity Labels; Amino Acids; Binding Sites; Circular Dichroism; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Enzyme Activation; Ethylmaleimide; Histidine; Hydroxymercuribenzoates; Indicators and Reagents; Kinetics; Lysine; Models, Chemical; o-Phthalaldehyde; Protease Inhibitors; Protein Binding; Protein Conformation; Sequence Analysis, Protein; Spectrometry, Fluorescence; Sulfhydryl Reagents; Time Factors; Trinitrobenzenesulfonic Acid; Urea; Xylan Endo-1,3-beta-Xylosidase; Xylosidases | 2001 |
Identification, substrate specificity, and inhibition of the Streptococcus pneumoniae beta-ketoacyl-acyl carrier protein synthase III (FabH).
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Amino Acid Sequence; Anti-Bacterial Agents; Asparagine; Catalysis; Chromatography; Circular Dichroism; Cloning, Molecular; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Guanidine; Histidine; Indoles; Inhibitory Concentration 50; Isoelectric Focusing; Kinetics; Models, Chemical; Molecular Sequence Data; Sequence Homology, Amino Acid; Streptococcus pneumoniae; Substrate Specificity; Thiophenes; Ultraviolet Rays | 2001 |
Association studies between haemochromatosis gene mutations and the risk of cardiovascular diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arteriosclerosis; Aspartic Acid; Brain Infarction; Cardiovascular Diseases; Case-Control Studies; Cysteine; Female; France; Genetic Predisposition to Disease; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Male; Membrane Proteins; Middle Aged; Mutation; Myocardial Infarction; Northern Ireland; Polymorphism, Genetic; Prevalence; Prospective Studies; Tyrosine; Ultrasonography; United Kingdom | 2001 |
Technetium-99m labelling of glycosylated somatostatin-14.
Topics: Chromatography, High Pressure Liquid; Cysteine; Dextrans; Glycosylation; Half-Life; Histidine; Hydrogen-Ion Concentration; Isotope Labeling; Somatostatin; Technetium | 2001 |
Distribution of amino acid residues and residue-residue contacts in molecular chaperones.
Topics: Amino Acids; Cysteine; Histidine; Molecular Chaperones; Protein Folding; Protein Structure, Secondary; Tryptophan | 2001 |
Structure of the Rho-activating domain of Escherichia coli cytotoxic necrotizing factor 1.
Topics: Amino Acid Sequence; Amino Acid Substitution; Bacterial Toxins; Binding Sites; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Cysteine; Cytotoxins; Enzyme Activation; Escherichia coli; Escherichia coli Proteins; Histidine; Models, Molecular; Molecular Sequence Data; Mutagenesis; Protein Structure, Secondary; Protein Structure, Tertiary; rho GTP-Binding Proteins; Sequence Alignment; Substrate Specificity | 2001 |
Structure, dynamics and electrostatics of the active site of glutaredoxin 3 from Escherichia coli: comparison with functionally related proteins.
Topics: Bacterial Proteins; Binding Sites; Computer Simulation; Cysteine; Enzyme Stability; Escherichia coli; Glutaredoxins; Histidine; Humans; Hydrogen Bonding; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Oxidation-Reduction; Oxidoreductases; Protein Conformation; Protein Disulfide-Isomerases; Proteins; Protons; Reproducibility of Results; Static Electricity; Thermodynamics; Thioredoxins; Titrimetry | 2001 |
Determination of the pK(a) of the four Zn2+-coordinating residues of the distal finger motif of the HIV-1 nucleocapsid protein: consequences on the binding of Zn2+.
Topics: Amino Acid Sequence; Apoproteins; Capsid; Capsid Proteins; Computer Simulation; Cysteine; Fluorescence; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Potentiometry; Protons; Spectrometry, Fluorescence; Thermodynamics; Viral Proteins; Zinc; Zinc Fingers | 2001 |
Effects of dimerization on protein electron transfer.
Topics: Algorithms; Asparagine; Azurin; Bacterial Proteins; Base Sequence; Copper; Cysteine; Dimerization; Electron Transport; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Magnetic Resonance Spectroscopy; Molecular Conformation; Mutagenesis; Plasmids; Pseudomonas aeruginosa; Zinc | 2001 |
19F NMR of trifluoroacetyl-labeled cysteine mutants of myoglobin: structural probes of nitric oxide bound to the H93G cavity mutant.
Topics: Animals; Carbon Monoxide; Cysteine; Dithionite; Fluorine; Glycine; Histidine; Ligands; Metmyoglobin; Mutagenesis, Site-Directed; Myoglobin; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protons; Sulfhydryl Compounds; Trifluoroacetic Acid; Whales | 2001 |
beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Chromatography; Cysteine; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myristic Acid; Plasmids; Protein Binding; Recombinant Proteins | 2001 |
Hemochromatosis gene variants in patients with cardiomyopathy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Cardiomyopathies; Cysteine; Disease Progression; Female; Genotype; Heart Failure; Hemochromatosis; Histidine; Humans; Logistic Models; Male; Middle Aged; Mutation, Missense; Prognosis; Tyrosine | 2001 |
A common inhibitory binding site for zinc and odorants at the voltage-gated K(+) channel of rat olfactory receptor neurons.
Topics: 4-Chloromercuribenzenesulfonate; Acetophenones; Animals; Binding Sites; Carbon Monoxide; Cells, Cultured; Cyclohexenes; Cysteine; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; Histidine; Limonene; Membrane Potentials; Mesylates; Neural Inhibition; Nitric Oxide; Olfactory Receptor Neurons; Patch-Clamp Techniques; Pentanols; Potassium; Potassium Channels; Rats; Receptors, Odorant; Smell; Sulfhydryl Reagents; Terpenes; Zinc | 2001 |
Hexa-histidine tag as a novel alternative for one-step direct labelling of a single-chain Fv antibody fragment with 99m Tc.
Topics: Animals; Antibodies, Monoclonal; Carcinoembryonic Antigen; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; Histidine; Immunoglobulin Variable Region; Isotope Labeling; Male; Mice; Mice, Inbred Strains; Peptide Fragments; Quality Control; Radiopharmaceuticals; Recombinant Proteins; Technetium; Tissue Distribution | 2001 |
Identification and characterization of the DNA binding domain of CpG-binding protein.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Base Sequence; Binding Sites; Blotting, Western; CpG Islands; Cysteine; DNA; DNA Methylation; Histidine; Humans; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Plasmids; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Transcriptional Activation; Zinc | 2001 |
C282Y and H63D mutations in the HFE gene have no effect on iron overload disorders in Japan.
Topics: Adult; Asian People; Aspartic Acid; Cysteine; Female; Hemochromatosis; Hemochromatosis Protein; Hepatitis C, Chronic; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Iron Overload; Japan; Liver Diseases; Male; Membrane Proteins; Middle Aged; Point Mutation; Polymerase Chain Reaction; Tyrosine | 2001 |
Beyond the "recognition code": structures of two Cys2His2 zinc finger/TATA box complexes.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; DNA; Histidine; Models, Molecular; Molecular Sequence Data; Protein Binding; Sequence Homology, Amino Acid; TATA Box; Zinc Fingers | 2001 |
The frequency of C282Y and H63D mutations in Hemochromatosis gene in native Estonians.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Aspartic Acid; Cysteine; DNA Mutational Analysis; DNA Primers; Estonia; Female; Gene Frequency; Genotype; Hemochromatosis; Histidine; Humans; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Tyrosine | 2001 |
Purification and characterization of an invertase produced by Aspergillus ochraceus TS.
Topics: Amino Acids; Arginine; Aspergillus; beta-Fructofuranosidase; Blotting, Western; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Ions; Kinetics; Mannose; Molecular Weight; Protein Binding; Sucrose | 2001 |
Anchoring of surface proteins to the cell wall of Staphylococcus aureus. Cysteine 184 and histidine 120 of sortase form a thiolate-imidazolium ion pair for catalysis.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Aminoacyltransferases; Bacterial Proteins; Binding Sites; Catalysis; Cell Wall; Cysteine; Cysteine Endopeptidases; Histidine; Hydrolysis; Imidazoles; Ions; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Peptides; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Staphylococcus aureus; Sulfhydryl Compounds; Time Factors; Tryptophan | 2002 |
Identification in Saccharomyces cerevisiae of a new stable variant of alkyl hydroperoxide reductase 1 (Ahp1) induced by oxidative stress.
Topics: Cysteine; Cytosol; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Histidine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Mutation; Oxidative Stress; Oxygen; Peroxidases; Peroxiredoxins; Plasmids; Protein Conformation; Saccharomyces cerevisiae; Sulfenic Acids; Superoxide Dismutase; tert-Butylhydroperoxide; Time Factors | 2002 |
Characterization of Glis2, a novel gene encoding a Gli-related, Krüppel-like transcription factor with transactivation and repressor functions. Roles in kidney development and neurogenesis.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cell Line; Cell Nucleus; Chromosome Mapping; Cysteine; DNA-Binding Proteins; DNA, Complementary; Gene Deletion; Gene Expression Regulation, Developmental; Gene Library; Histidine; Humans; In Situ Hybridization; In Situ Hybridization, Fluorescence; Kidney; Kruppel-Like Transcription Factors; Luciferases; Mice; Models, Genetic; Molecular Sequence Data; Neural Crest; Neurons; Plasmids; Protein Binding; Protein Structure, Tertiary; Rats; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Tissue Distribution; Transcriptional Activation; Two-Hybrid System Techniques; Zinc Fingers | 2002 |
Twists and turns of the cation-dependent mannose 6-phosphate receptor. Ligand-bound versus ligand-free receptor.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Cysteine; Cytoplasm; Dimerization; Endosomes; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Ligands; Models, Molecular; Molecular Sequence Data; Phosphates; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Receptor, IGF Type 2; Sequence Homology, Amino Acid | 2002 |
Amino acid modulation of in vivo intestinal zinc absorption in freshwater rainbow trout.
Topics: Amino Acids; Animals; Cysteine; Epithelium; Histidine; Intestinal Absorption; Oncorhynchus mykiss; Taurine; Zinc | 2002 |
Direct proton magnetic resonance determination of the pKa of the active center histidine in thiolsubtilisin.
Topics: Binding Sites; Cysteine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Conformation; Serine Endopeptidases; Subtilisins | 2002 |
Zn(2+) binding properties of single-point mutants of the C-terminal zinc finger of the HIV-1 nucleocapsid protein: evidence of a critical role of cysteine 49 in Zn(2+) dissociation.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Capsid; Capsid Proteins; Cobalt; Cysteine; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Histidine; HIV-1; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Sequence Data; Point Mutation; Protein Binding; Serine; Spectrophotometry; Viral Proteins; Zinc; Zinc Fingers | 2002 |
The crystal structure of Mycobacterium tuberculosis alkylhydroperoxidase AhpD, a potential target for antitubercular drug design.
Topics: Antitubercular Agents; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cysteine; Dimerization; Histidine; Models, Chemical; Models, Molecular; Mycobacterium tuberculosis; Peroxidases; Peroxiredoxins; Protein Binding; Selenomethionine | 2002 |
Function assignment to conserved residues in mammalian alkaline phosphatases.
Topics: Alkaline Phosphatase; Animals; Binding Sites; Conserved Sequence; Cysteine; Disulfides; Dose-Response Relationship, Drug; Epitopes; Histidine; Humans; Kinetics; Leucine; Ligands; Magnesium; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Software; Spectrometry, Fluorescence; Time Factors; Tyrosine; Zinc | 2002 |
Effects of amino acid substitutions at beta 131 on the structure and properties of hemoglobin: evidence for communication between alpha 1 beta 1- and alpha 1 beta 2-subunit interfaces.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; Cysteine; Globins; Glutamine; Hemoglobin A; Histidine; Humans; Hydrogen Bonding; Mercuribenzoates; Nuclear Magnetic Resonance, Biomolecular; Oxygen; Protein Conformation; Protons; Recombinant Proteins; Structure-Activity Relationship; Sulfhydryl Reagents | 2002 |
Tripodal pseudopeptides with three histidine or cysteine donors: synthesis and zinc complexation.
Topics: Cysteine; Histidine; Metalloproteins; Molecular Mimicry; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Tricarboxylic Acids; Zinc | 2002 |
Quantitative proteomics strategy involving the selection of peptides containing both cysteine and histidine from tryptic digests of cell lysates.
Topics: Amino Acid Sequence; Chromatography, Liquid; Cysteine; Escherichia coli; Histidine; Molecular Sequence Data; Peptide Mapping; Peptides; Proteome; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin | 2002 |
A new zinc binding fold underlines the versatility of zinc binding modules in protein evolution.
Topics: Amino Acid Sequence; Animals; Binding Sites; Circular Dichroism; CREB-Binding Protein; Cysteine; Evolution, Molecular; Histidine; Mice; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Peptides; Protein Folding; Protein Structure, Tertiary; Sequence Alignment; Temperature; Trans-Activators; Zinc | 2002 |
Enthalpic homogeneous pair interaction coefficients of L-alpha-amino acids as a hydrophobicity parameter of amino acid side chains.
Topics: Amino Acids; Arginine; Asparagine; Calorimetry; Cysteine; Glutamic Acid; Glutamine; Histidine; Solutions; Stereoisomerism; Thermodynamics; Tryptophan; Water | 2002 |
The local electrostatic environment determines cysteine reactivity of tubulin.
Topics: Acetamides; Animals; Cysteine; Electrons; Enzyme Inhibitors; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics; Ligands; Lysine; Mass Spectrometry; Models, Molecular; Palmitic Acids; Peptides; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Static Electricity; Sulfides; Time Factors; Trypsin; Tubulin | 2002 |
Characterization of binding and utilization of hemoglobin by Prevotella nigrescens.
Topics: Arginine; Bacterial Proteins; Catalase; Cysteine; Cytochrome c Group; Disaccharides; Globins; Hemoglobins; Hexoses; Histidine; Hot Temperature; Humans; Immunoblotting; Iron; Lactoferrin; Lysine; Prevotella; Protein Binding; Transferrin; Trypsin | 2002 |
Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase.
Topics: Amino Acid Sequence; Amino Acids; Amino Acyl-tRNA Synthetases; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Escherichia coli; Histidine; Ions; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; RNA, Transfer; Sequence Homology, Amino Acid; Zinc | 2002 |
The crystal structure of metal-free human EF-hand protein S100A3 at 1.7-A resolution.
Topics: Amino Acid Sequence; Androstadienes; Binding Sites; Calcium; Calcium-Binding Proteins; Circular Dichroism; Crystallography, X-Ray; Cysteine; Dimerization; EF Hand Motifs; Escherichia coli; Histidine; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Structure, Tertiary; S100 Proteins; Signal Transduction; Wortmannin; Zinc | 2002 |
The role of GyrB in the DNA cleavage-religation reaction of DNA gyrase: a proposed two metal-ion mechanism.
Topics: Adenosine Triphosphatases; Catalytic Domain; Cations, Divalent; Crystallography, X-Ray; Cysteine; DNA Gyrase; DNA, Superhelical; Escherichia coli; Genetic Complementation Test; Histidine; Magnesium; Manganese; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation | 2002 |
Prevalence of hemochromatosis-related symptoms among individuals with mutations in the HFE gene.
Topics: Adult; Aged; Aspartic Acid; Case-Control Studies; Cysteine; Double-Blind Method; Female; Ferritins; Genetic Predisposition to Disease; Genetic Testing; Genotype; Hemochromatosis; Hispanic or Latino; Histidine; Homozygote; Humans; Male; Middle Aged; Mutation; Prevalence; Surveys and Questionnaires; Transferrin; Tyrosine; United States; White People | 2002 |
Redox control of zinc finger proteins.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Cysteine; DNA; Histidine; Humans; Methionine; Molecular Sequence Data; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Receptors, Estrogen; Spectrometry, Mass, Electrospray Ionization; Zinc; Zinc Fingers | 2002 |
The ferric uptake regulator of Pseudomonas aeruginosa has no essential cysteine residues and does not contain a structural zinc ion.
Topics: Bacterial Proteins; Binding Sites; Carrier Proteins; Circular Dichroism; Cysteine; Escherichia coli; Ferric Compounds; Histidine; Maltose-Binding Proteins; Protein Conformation; Pseudomonas aeruginosa; Recombinant Fusion Proteins; Repressor Proteins; Spectrometry, Fluorescence; Zinc | 2002 |
The gate of the influenza virus M2 proton channel is formed by a single tryptophan residue.
Topics: Animals; Cell Membrane; Cysteine; DNA, Complementary; Histidine; Hydrogen-Ion Concentration; Ions; Kinetics; Membrane Potentials; Mesylates; Mutation; Oocytes; Protein Binding; Protein Structure, Tertiary; Time Factors; Tryptophan; Viral Matrix Proteins; Xenopus laevis | 2002 |
Formation of a copper specific binding site in non-native states of beta-2-microglobulin.
Topics: Amino Acid Sequence; Animals; beta 2-Microglobulin; Binding Sites; Circular Dichroism; Copper; Cysteine; Histidine; Humans; Mass Spectrometry; Models, Molecular; Mutation; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Sequence Homology, Amino Acid; Structure-Activity Relationship; Thermodynamics | 2002 |
Binding of D- and L-captopril inhibitors to metallo-beta-lactamase studied by polarizable molecular mechanics and quantum mechanics.
Topics: Algorithms; Aspartic Acid; Bacteroides fragilis; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Captopril; Computational Biology; Cysteine; Enzyme Inhibitors; Histidine; Models, Molecular; Molecular Structure; Protein Conformation; Serine; Static Electricity; Stereoisomerism; Zinc | 2002 |
Cys(x)His(y)-Zn2+ interactions: thiol vs. thiolate coordination.
Topics: Cysteine; Databases, Protein; Histidine; Imidazoles; Ligands; Macromolecular Substances; Metalloproteins; Molecular Structure; Protons; Solvents; Sulfhydryl Compounds; Thermodynamics; Zinc | 2002 |
Crystal structure of microbial transglutaminase from Streptoverticillium mobaraense.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalysis; Cross-Linking Reagents; Crystallography, X-Ray; Cysteine; Escherichia coli; Histidine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Streptomyces; Structure-Activity Relationship; Transglutaminases | 2002 |
Conserved residues in the putative catalytic triad of human bile acid Coenzyme A:amino acid N-acyltransferase.
Topics: Acyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Aspartic Acid; Bile Acids and Salts; Catalysis; Catalytic Domain; Cholic Acids; Coenzyme A; Conserved Sequence; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Ethylmaleimide; Histidine; Humans; Kinetics; Models, Chemical; Molecular Sequence Data; Mutation; Protein Binding; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Time Factors; Trypsin | 2002 |
Ligand binding properties and structural studies of recombinant and chemically modified hemoglobins altered at beta 93 cysteine.
Topics: 2,3-Diphosphoglycerate; Allosteric Regulation; Amino Acid Substitution; Cysteine; Globins; Heme; Hemoglobin A; Hemoglobins; Histidine; Humans; Ligands; Methemoglobin; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Oxygen; Phytic Acid; Protein Subunits; Recombinant Proteins; Structure-Activity Relationship; Thermodynamics | 2002 |
The Arabidopsis SUPERMAN protein is able to specifically bind DNA through its single Cys2-His2 zinc finger motif.
Topics: Amino Acid Sequence; Amino Acids, Basic; Arabidopsis Proteins; Binding Sites; Cysteine; DNA; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Histidine; Molecular Sequence Data; Sequence Deletion; Transcription Factors; Zinc Fingers | 2002 |
Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal.
Topics: Aldehydes; Amino Acids; Arginine; Cysteine; Histidine; Kinetics; Lipid Peroxidation; Lysine; Protein Processing, Post-Translational; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2002 |
Cloning, overexpression, and characterization of a bacterial Ca2+-dependent phospholipase D.
Topics: Amino Acid Sequence; Calcium; Cloning, Molecular; Cysteine; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Gene Expression; Histidine; Inhibitory Concentration 50; Molecular Sequence Data; Mutation; Phospholipase D; Recombinant Proteins; Sequence Alignment; Sequence Homology; Streptomyces | 2002 |
Effects of polyunsaturated fatty acids on voltage-gated K+ and Na+ channels in rat olfactory receptor neurons.
Topics: Acetophenones; Animals; Arachidonic Acid; Cell Membrane; Cells, Cultured; Cyclohexenes; Cysteine; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Histidine; Limonene; Membrane Potentials; Neural Inhibition; Olfactory Receptor Neurons; Pentanols; Potassium Channels, Voltage-Gated; Rats; Signal Transduction; Smell; Sodium Channels; Terpenes | 2002 |
A Cys3His zinc-binding domain from Nup475/tristetraprolin: a novel fold with a disklike structure.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Conserved Sequence; Crystallography, X-Ray; Cysteine; DNA-Binding Proteins; Histidine; Humans; Hydrophobic and Hydrophilic Interactions; Immediate-Early Proteins; Mice; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Folding; Protein Structure, Tertiary; Solutions; Tristetraprolin; Zinc Fingers | 2003 |
Substrate recognition and molecular mechanism of fatty acid hydroxylation by cytochrome P450 from Bacillus subtilis. Crystallographic, spectroscopic, and mutational studies.
Topics: Arginine; Bacillus subtilis; Binding Sites; Crystallography, X-Ray; Cysteine; Cytochrome P-450 Enzyme System; Escherichia coli; Fatty Acids; Glutamic Acid; Histidine; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Myristic Acid; Oxygen; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Spectrophotometry; Spectrum Analysis, Raman; Substrate Specificity | 2003 |
Association between hemochromatosis (HFE) gene mutation carrier status and the risk of colon cancer.
Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies; Colonic Neoplasms; Cysteine; Feeding Behavior; Female; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; Humans; Iron Compounds; Male; Meat; Membrane Proteins; Middle Aged; Mutation; North Carolina; Risk Assessment; Risk Factors; Tyrosine | 2003 |
Active-site mutants of class B beta-lactamases: substrate binding and mechanistic study.
Topics: Bacillus cereus; Bacterial Proteins; beta-Lactamases; Binding Sites; Crystallography, X-Ray; Cysteine; Histidine; Molecular Structure; Mutation; Penicillin G; Penicillins; Protein Binding | 2002 |
N-isotope effects on the Raman spectra of Fe(2)S(2) ferredoxin and Rieske ferredoxin: evidence for structural rigidity of metal sites.
Topics: Anabaena; Bacterial Proteins; Binding Sites; Cysteine; Ferredoxins; Histidine; Iron Compounds; Nitrogen Isotopes; Pseudomonas; Spectrum Analysis, Raman | 2003 |
The dual activity of pyruvate kinase type M2 from chromatin extracts of neoplastic cells.
Topics: Adenosine Triphosphate; Animals; Arginine; Cell Fractionation; Chromatin; Cysteine; Cytosol; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Histidine; Isoenzymes; Liver; Liver Neoplasms, Experimental; Phosphoenolpyruvate; Pyruvate Kinase; Rats; Rats, Inbred BUF | 2003 |
Modeling zinc in biomolecules with the self consistent charge-density functional tight binding (SCC-DFTB) method: applications to structural and energetic analysis.
Topics: Alcohol Dehydrogenase; Algorithms; Aminopeptidases; Aspartic Acid; Bacterial Proteins; Binding Sites; Carbonic Anhydrases; Cysteine; Glutamic Acid; Histidine; Liver; Models, Molecular; Molecular Conformation; Protein Binding; Protein Conformation; Water; Zinc | 2003 |
A novel zinc snap motif conveys structural stability to 3-methyladenine DNA glycosylase I.
Topics: Amino Acid Sequence; Bacteria; Binding Sites; Cobalt; Conserved Sequence; Cysteine; DNA Glycosylases; DNA Repair; Escherichia coli; Histidine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Molecular Structure; N-Glycosyl Hydrolases; Sequence Alignment; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet; Zinc; Zinc Fingers | 2003 |
Inhibition of Streptomyces chromofuscus phospholipase D activity by dichloro-(2,2':6',2''-terpyridine)-platinum (II) dihydrate.
Topics: Aluminum Compounds; Amino Acid Motifs; Brassica; Calcium; Conserved Sequence; Cysteine; Enzyme Inhibitors; Ethylmaleimide; Fluorides; Histidine; Hydrolysis; Isoenzymes; Phospholipase D; Platinum Compounds; Streptomyces; Structure-Activity Relationship | 2002 |
Thioredoxin motif of Caenorhabditis elegans PDI-3 provides Cys and His catalytic residues for transglutaminase activity.
Topics: Amino Acid Motifs; Animals; Caenorhabditis elegans Proteins; Catalytic Domain; Cysteine; Glutamine; Histidine; Mutagenesis, Site-Directed; Protein Disulfide-Isomerases; Recombinant Proteins; Thioredoxins; Transglutaminases | 2003 |
CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Circular Dichroism; Cysteine; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Histidine; Humans; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrophotometry, Atomic; Ultracentrifugation; Ultraviolet Rays; Zinc; Zinc Fingers | 2003 |
The mechanism of Mycobacterium tuberculosis alkylhydroperoxidase AhpD as defined by mutagenesis, crystallography, and kinetics.
Topics: Antioxidants; Bacterial Proteins; Binding Sites; Catalysis; Catalytic Domain; Cell Division; Crystallography, X-Ray; Cysteine; Dimerization; Disulfides; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Mycobacterium tuberculosis; Oxygen; Peroxidases; Peroxiredoxins; Protein Conformation; Protons; Thioredoxins; Ultraviolet Rays | 2003 |
Population screening for hemochromatosis: a study in 5370 Spanish blood donors.
Topics: Adult; Aspartic Acid; Blood Donors; Cysteine; Female; Ferritins; Gene Frequency; Genetic Testing; Genotype; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; Homozygote; Humans; Male; Membrane Proteins; Middle Aged; Mutation; Sex Characteristics; Spain; Transferrin; Tyrosine | 2003 |
Structure-function analysis of recombinant substrate protein 22 kDa (SP-22). A mitochondrial 2-CYS peroxiredoxin organized as a decameric toroid.
Topics: Animals; Catalysis; Cattle; Circular Dichroism; Cloning, Molecular; Cross-Linking Reagents; Cysteine; Cystine; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Microscopy, Electron; Mitochondria; Mutagenesis, Site-Directed; Mutation; Peroxidases; Peroxiredoxins; Phosphopyruvate Hydratase; Protein Folding; Protein Structure, Quaternary; Protein Structure, Secondary; Structure-Activity Relationship | 2003 |
The human bile acid-CoA:amino acid N-acyltransferase functions in the conjugation of fatty acids to glycine.
Topics: Acyltransferases; Amino Acid Sequence; Animals; Aspartic Acid; Bile Acids and Salts; Catalysis; Cloning, Molecular; Cysteine; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fatty Acids; Fibroblasts; Gallbladder; Glycine; Green Fluorescent Proteins; Histidine; Humans; Intestines; Kinetics; Liver; Luminescent Proteins; Mass Spectrometry; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Recombinant Fusion Proteins; Recombinant Proteins; Taurine; Tissue Distribution | 2003 |
Functional characterization of cysteine residues in GlpT, the glycerol 3-phosphate transporter of Escherichia coli.
Topics: 4-Chloromercuribenzenesulfonate; Biological Transport; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Immunoblotting; Membrane Transport Proteins; Mesylates; Mutagenesis, Site-Directed; Proteolipids; Structure-Activity Relationship; Substrate Specificity; Sulfhydryl Reagents | 2003 |
Histidine 140 plays a key role in the inhibitory modulation of the P2X4 nucleotide receptor by copper but not zinc.
Topics: Adenosine Triphosphate; Allosteric Site; Animals; Binding Sites; Cell Line; Copper; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Histidine; Humans; Metals; Mutagenesis, Site-Directed; Mutation; Oocytes; Patch-Clamp Techniques; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Time Factors; Transfection; Xenopus laevis; Zinc | 2003 |
Sortase from Staphylococcus aureus does not contain a thiolate-imidazolium ion pair in its active site.
Topics: Aminoacyltransferases; Bacterial Proteins; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Cysteine; Cysteine Endopeptidases; Histidine; Hydrogen-Ion Concentration; Imidazoles; Ions; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Peptides; Peptidyl Transferases; Staphylococcus aureus; Sulfhydryl Compounds; Sulfones; Time Factors | 2003 |
The Cys-Xaa-His metal-binding motif: [N] versus [S] coordination and nickel-mediated formation of cysteinyl sulfinic acid.
Topics: Alkylation; Amino Acid Motifs; Chromatography, High Pressure Liquid; Copper; Cysteine; Glycine; Histidine; Humans; Hydrogen-Ion Concentration; Lysine; Metalloproteins; Metals; Molecular Structure; Neurotransmitter Agents; Nickel; Oxidation-Reduction; Peptides | 2003 |
Electrostatic properties in the catalytic site of papain: A possible regulatory mechanism for the reactivity of the ion pair.
Topics: Amino Acids; Binding Sites; Catalytic Domain; Cysteine; Histidine; Ion Transport; Ions; Ligands; Models, Chemical; Osmolar Concentration; Papain; Protons; Solvents; Static Electricity; Water | 2003 |
A novel zinc finger is required for Mcm10 homocomplex assembly.
Topics: Alleles; Amino Acid Motifs; Amino Acids; beta-Galactosidase; Blotting, Western; Cell Cycle Proteins; Cell Division; Chromatography, Gel; Chromosomal Proteins, Non-Histone; Cysteine; DNA; Fungal Proteins; Genetic Vectors; Glutathione Transferase; Histidine; Magnetic Resonance Spectroscopy; Minichromosome Maintenance Proteins; Peptides; Phenotype; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Zinc; Zinc Fingers | 2003 |
A template search reveals mechanistic similarities and differences in beta-ketoacyl synthases (KAS) and related enzymes.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Binding Sites; Computational Biology; Cysteine; Databases, Protein; Enzymes; Histidine; Isoenzymes; Malonyl Coenzyme A; Molecular Structure | 2003 |
Structure-based thermodynamic analysis of caspases reveals key residues for dimerization and activity.
Topics: Amino Acid Sequence; Apoptosis; Binding Sites; Caspase 3; Caspase 7; Caspases; Cysteine; Dimerization; Enzyme Activation; Histidine; HIV Protease; Hydrogen Bonding; Kinetics; Models, Biological; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Streptomyces; Temperature; Thermodynamics | 2003 |
Bioadsorption of cadmium ion by cell surface-engineered yeasts displaying metallothionein and hexa-His.
Topics: Adsorption; Cadmium; Cell Membrane; Culture Media; Cysteine; Edetic Acid; Genetic Engineering; Histidine; Metallothionein; Plasmids; Saccharomyces cerevisiae | 2003 |
Amino acid discrimination by a highly differentiated metal center of an aminoacyl-tRNA synthetase.
Topics: Adenosine Triphosphate; Amino Acids; Amino Acyl-tRNA Synthetases; Binding Sites; Circular Dichroism; Crystallography, X-Ray; Cysteine; Escherichia coli; Histidine; Imidazoles; Kinetics; Ligands; Models, Molecular; Mutation; Protein Binding; Protein Conformation; RNA, Transfer; Zinc | 2003 |
Preparation of the optical isomers of arginine, histidine and S-benzylcysteine by asymmetric enzymatic hydrolysis of their acetyl derivatives.
Topics: Arginine; Cysteine; Histidine; Hydrolysis; Isomerism | 1952 |
Reaction of ethylene oxide with histidine, methionine, and cysteine.
Topics: Cysteine; Ethylene Oxide; Histidine; Methionine; Proteins | 1959 |
[Increase in the radiochemical formation of histamine from histidine by means of cysteine].
Topics: Cysteine; Histamine; Histidine; Radiochemistry; Radiopharmaceuticals | 1960 |
Reaction of histidine with the biuret reagent in the presence of oxygen.
Topics: Biuret; Cysteine; Histidine; Indicators and Reagents; Oxygen | 1963 |
Amino acid dependent control of DNA synthesis in bacteria and vegetative phage.
Topics: Amino Acids; Arginine; Coliphages; Cysteine; DNA; DNA, Bacterial; Escherichia coli; Histidine; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan | 1962 |
ENVIRONMENTAL CONTROL OF THE COURSE OF DEVELOPMENT IN DICTYOSTELIUM DISCOIDEUM.
Topics: Alanine; Calcium; Calcium, Dietary; Carbohydrate Metabolism; Chlorides; Citrates; Culture Media; Cysteine; Dictyostelium; Fungi; Glucose; Glycine; Histidine; Hydrogen-Ion Concentration; Magnesium; Potassium; Proteins; Sodium; Succinates | 1963 |
[THE DEAMINATION OF SEVERAL AMINO ACIDS IN THE LIVER OF EMBRYOS DURING THE TRANSITION FROM UREOTELISM TO URICOTELISM].
Topics: Amino Acids; Aspartic Acid; Chick Embryo; Cysteine; Deamination; Glutamates; Histidine; Hydroxylamines; Liver; Ornithine; Pharmacology; Proteins; Research; Urea; Uric Acid; Valine | 1963 |
STUDIES ON COLLETOTRICHUM CAPSICI III. THE EFFECT OF INITIAL PH ON THE GROWTH AND AMINO ACID COMPOSITION.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Chromatography; Colletotrichum; Cysteine; Fungi; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Phenylalanine; Research; Serine; Tyrosine | 1963 |
A MANOMETRIC DETERMINATION OF SULFHYDRYL GROUPS AND ITS APPLICATION TO PROTEINS IN NATIVE AND DENATURED STATES.
Topics: Arginine; Cysteine; Erythrocytes; Glutathione; Hemoglobins; Histidine; Insulin; Manometry; Ovalbumin; Proline; Proteins; Pyridines; Research; Serum Albumin; Sulfhydryl Compounds; Tyrosine | 1963 |
[CONCERNING THE HISTOCHEMISTRY AND ULTRASTRUCTURE OF THE VITELLINE GRANULES IN THE GALLUS DOMESTICUS EGG].
Topics: Animals; Arginine; Chickens; Cysteine; Cystine; Egg Yolk; Glycoproteins; Histidine; Histocytochemistry; Phospholipids; Polysaccharides; Research; Tryptophan; Tyrosine | 1963 |
EFFECT OF AMINO ACIDS ON UPTAKE OF L-HISTIDINE BY RAT BRAIN SLICES.
Topics: Amino Acids; Arginine; Brain; Chromatography; Culture Media; Cysteine; Cystine; Dipeptides; Glutamates; Histidine; Hydroxyproline; Isoleucine; Leucine; Metabolism; Phenylalanine; Pimelic Acids; Proline; Rats; Research; Taurine; Tryptophan; Valine | 1964 |
EFFECT OF CHELATING AGENTS ON THE GROWTH OF ESCHERICHIA COLI IN SEAWATER.
Topics: Chelating Agents; Cysteine; Edetic Acid; Escherichia coli; Glycine; Histidine; Metals, Heavy; Methionine; Phenanthrolines; Research; Seawater; Sodium Chloride; Toxicology; Water Microbiology; Water Pollution | 1964 |
BIOSYNTHESIS OF BACITRACIN. I. FORMATION OF BACITRACIN BY A SUBCELLULAR FRACTION OF BACILLUS LICHENIFORMIS.
Topics: Asparagine; Aspartic Acid; Bacillus; Bacitracin; Carbon Isotopes; Chromatography; Cysteine; Cystine; Glutamates; Glutathione; Histidine; Isoleucine; Lysine; Metabolism; Micrococcus; Ornithine; Phenylalanine; Research; Subcellular Fractions; Sulfhydryl Compounds; Sulfur Isotopes | 1964 |
A SIMPLE PREPARATION METHOD FOR DIPHOSPHOMIDAZOLE.
Topics: Alanine; Amides; Calcium Phosphates; Chlorides; Chromatography; Cysteine; Cystine; Glycine; Histidine; Imidazoles; Ion Exchange Resins; Methionine; Phosphates; Phosphorus; Research; Serine; Tryptophan; Tyrosine | 1964 |
NUTRITIONAL FACTORS RELATING TO GROWTH AND OXYTETRACYCLINE FORMATION BY STREPTOMYCES RIMOSUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Cysteine; Cystine; Glutamine; Glycine; Histidine; Isoleucine; Lysine; Metabolism; Methionine; Oxytetracycline; Research; Serine; Streptomyces; Streptomyces rimosus | 1964 |
STUDIES ON D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES. XXI. SOME DATA ON THE BINDING OF ZN IN THE ENZYME.
Topics: Chemical Phenomena; Chemistry; Chloromercuribenzoates; Coenzymes; Cysteine; Glyceraldehyde; Glyceraldehyde-3-Phosphate Dehydrogenases; Histidine; Oxidation-Reduction; Phosphates; Research; Spectrophotometry; Sulfhydryl Compounds; Zinc; Zinc Isotopes | 1964 |
CLUSTERING OF FUNCTIONALLY RELATED GENES IN SALMONELLA TYPHIMURIUM.
Topics: Arginine; Cysteine; Escherichia coli; Glycine; Guanine; Histidine; Isoleucine; Leucine; Metabolism; Methionine; Molecular Biology; Mutation; Pantothenic Acid; Proline; Purines; Pyrimidines; Research; Salmonella typhimurium; Serine; Threonine; Tryptophan | 1964 |
SOME IN VITRO STUDIES OF POLONIUM-210 BINDING BY BLOOD CONSTITUENTS.
Topics: Amino Acids; Aspartic Acid; Bicarbonates; Blood; Citrates; Cysteine; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Malates; Metabolism; Phosphates; Polonium; Research; Serine; Tryptophan | 1964 |
RECOMBINATION BETWEEN NOCARDIA ERYTHROPOLIS AND NOCARDIA CANICRURIA.
Topics: Adenine; Alanine; Anti-Bacterial Agents; Arginine; Cysteine; Cystine; Drug Resistance; Drug Resistance, Microbial; Glycine; Guanine; Histidine; Hypoxanthines; Isoleucine; Leucine; Lysine; Metabolism; Methionine; Mutation; Nocardia; Recombination, Genetic; Research; Streptomycin; Valine; Xanthines | 1964 |
AMINO ACIDS AS PROTECTIVE COMPOUNDS IN ULTRAVIOLET-IRRADIATED HANSENULA WINGEI.
Topics: Alanine; Amino Acids; Arginine; Cysteine; Cystine; Ethionine; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Pichia; Proline; Radiation-Protective Agents; Research; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays; Valine; Yeasts | 1964 |
SELENOAMINO ACIDS AS RADIATION PROTECTORS IN VITRO.
Topics: Alanine; Alcohol Oxidoreductases; Amino Acids; Arginine; Cysteine; Cystine; Histidine; In Vitro Techniques; Leucine; Methionine; Phenylalanine; Radiation-Protective Agents; Research; Ribonucleases; Selenium; Serine | 1964 |
L-CYSTEINE AS INHIBITOR OF POTASSIUM RETENTION BY BRAIN SLICES.
Topics: Amino Acids; Antimetabolites; Biological Transport; Brain; Brain Chemistry; Cysteine; Histidine; Pharmacology; Potassium; Rats; Research | 1964 |
THE EXISTENCE OF A HISTIDINE RESIDUE ESSENTIAL FOR GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE ACTION.
Topics: Animals; Chemical Phenomena; Chemistry; Cysteine; Glyceraldehyde; Glyceraldehyde-3-Phosphate Dehydrogenases; Histidine; Kinetics; Light; Metabolism; Oxidation-Reduction; Phosphates; Research; Spectrophotometry; Swine | 1964 |
BLOOD-FREE MEDIUM FOR THE RAPID GROWTH OF PASTEURELLA TULARENSIS.
Topics: Agar; Buffers; Culture Media; Cysteine; Francisella tularensis; Glucose; Histidine; Humidity; Iron; Potassium; Potassium Chloride; Research; Tromethamine | 1964 |
[GENETIC STUDY OF COLICINOGENIC FACTOR B AND ITS INFLUENCE ON THE FERTILITY OF CROSSES IN ESCHERICHIA COLI K 12].
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Arginine; Colicins; Complement Factor B; Cysteine; Escherichia coli; Fertility; Genetics; Histidine; Hybridization, Genetic; Leucine; Methionine; Research; Streptomycin; Thiamine; Threonine; Tryptophan | 1964 |
A NEW REAGENT FOR NITROGUANIDINATION OF PROTEINS.
Topics: Amino Acids; Animals; Cattle; Chemistry Techniques, Analytical; Cysteine; Electrophoresis; Guanidines; Histidine; Indicators and Reagents; Indoles; Molecular Weight; Phenols; Proteins; Pyrazoles; Research; Serum Albumin; Serum Albumin, Bovine; Tryptophan; Tyrosine; Ultracentrifugation | 1964 |
BIPOLARITY OF INFORMATION TRANSFER FROM THE SALMONELLA TYPHIMURIUM CHROMOSOME.
Topics: Arabinose; Chromosomes; Chromosomes, Bacterial; Cysteine; DNA; DNA, Bacterial; Galactose; Genetics; Histidine; Isoleucine; Leucine; Mutation; Operon; Research; RNA; RNA, Messenger; Salmonella typhimurium; Threonine; Tryptophan | 1965 |
STUDIES ON THE ACTIVE SITE OF THE A PROTEIN SUBUNIT OF THE ESCHERICHIA COLI TRYPTOPHAN SYNTHETASE.
Topics: Bacterial Proteins; Biochemical Phenomena; Biochemistry; Carbon Isotopes; Catalysis; Catalytic Domain; Cysteine; Enzyme Inhibitors; Escherichia coli; Ethylmaleimide; Histidine; Hydro-Lyases; Iodoacetates; Kinetics; Light; Methionine; Molecular Biology; Protein Subunits; Pyrroles; Research; Tryptophan Synthase; Urea | 1965 |
ANALYSIS OF PROTON MAGNETIC RESONANCE SPECTRA OF CYSTEINE AND HISTIDINE AND DERIVATIVES. CONFORMATIONAL EQUILIBRIA.
Topics: Chemical Phenomena; Chemistry, Physical; Cysteine; Histidine; Magnetic Resonance Spectroscopy; Molecular Conformation; Protons; Research | 1965 |
RELATION OF BIOCHEMICAL MUTATIONS TO ACTINOMYCIN SYNTHESIS IN STREPTOMYCES ANTIBIOTICUS.
Topics: Adenine; Amino Acids; Arginine; Culture Media; Cysteine; Dactinomycin; Histidine; Isoleucine; Leucine; Metabolism; Methionine; Mutation; Phenylalanine; Research; Streptomyces; Streptomyces antibioticus; Threonine; Tyrosine; Ultraviolet Rays; Uracil; Valine | 1965 |
THE PERIODATE OXIDATION OF AMINO ACIDS WITH REFERENCE TO STUDIES ON GLYCOPROTEINS.
Topics: Amino Acids; Cysteine; Cystine; Glycoproteins; Histidine; Hydrogen-Ion Concentration; Hydroxyproline; Indoles; Isoleucine; Leucine; Methionine; Oxidation-Reduction; Periodic Acid; Phenylalanine; Proline; Pyrroles; Research; Serine; Threonine; Tryptophan; Tyrosine | 1965 |
The potentiation by histidine of the induction of respiration deficient yeast by allyl glycine.
Topics: Cell Respiration; Cysteine; Glycine; Histidine; Saccharomyces cerevisiae; Yeasts | 1961 |
The crystal structure of Escherichia coli heat shock protein YedU reveals three potential catalytic active sites.
Topics: Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cysteine; Dimerization; Electronic Data Processing; Escherichia coli Proteins; Glutamic Acid; Heat-Shock Proteins; Histidine; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Chaperones; Molecular Sequence Data; Protein Structure, Quaternary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Structural Homology, Protein; Zinc | 2003 |
Formation of S-[2-carboxy-1-(1H-imidazol-4-yl) ethyl]glutathione, a new metabolite of L-histidine, from cis-urocanic acid and glutathione by the action of glutathione S-transferase.
Topics: Animals; Cysteine; Electrophoresis, Capillary; Electrophoresis, Paper; Glutathione; Glutathione Transferase; Histidine; Imidazoles; Liver; Rats; Rats, Wistar; Skin; Spectrometry, Mass, Fast Atom Bombardment; Stereoisomerism; Sunlight; Urocanic Acid | 2003 |
Methanethiosulfonate derivatives of rhodamine and verapamil activate human P-glycoprotein at different sites.
Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Binding Sites; Biological Transport; Calcium Channel Blockers; Cell Line; Colchicine; Cysteine; Disulfides; DNA, Complementary; Dose-Response Relationship, Drug; Fluoresceins; Fluorescent Dyes; Histidine; Humans; Mesylates; Models, Biological; Models, Chemical; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rhodamines; Verapamil | 2003 |
The redox state of the cell regulates the ligand binding affinity of human neuroglobin and cytoglobin.
Topics: Cysteine; Cytoglobin; Disulfides; Globins; Histidine; Humans; Kinetics; Ligands; Models, Molecular; Nerve Tissue Proteins; Neuroglobin; Oxidation-Reduction; Oxygen; Protein Binding; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization | 2003 |
The redox domain of the Yap1p transcription factor contains two disulfide bonds.
Topics: Amino Acid Sequence; Cysteine; Disulfides; Histidine; Molecular Sequence Data; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Saccharomyces cerevisiae Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship; Transcription Factors | 2003 |
Oxidative inactivation of purified plasma membrane Ca2+-ATPase by hydrogen peroxide and protection by calmodulin.
Topics: Animals; Calcium-Transporting ATPases; Calmodulin; Cation Transport Proteins; Cattle; Cysteine; Dithiothreitol; Enzyme Activation; Erythrocyte Membrane; Histidine; Humans; Hydrogen Peroxide; Leucine; Oxidation-Reduction; Plasma Membrane Calcium-Transporting ATPases; Protein Conformation; Serine; Spectrometry, Fluorescence; Tyrosine; Valine | 2003 |
Identification of novel GDAP1 mutations causing autosomal recessive Charcot-Marie-Tooth disease.
Topics: Alleles; Arginine; Charcot-Marie-Tooth Disease; Cysteine; Demyelinating Diseases; DNA Mutational Analysis; Electrophysiology; Family Health; Female; Genetic Predisposition to Disease; Glycine; Histidine; Humans; Male; Microscopy, Electron; Mutation; Nerve Tissue Proteins; Neural Conduction; Pedigree; Peripheral Nerves; Sequence Analysis, DNA; Tryptophan | 2003 |
Cys32 and His105 are the critical residues for the calcium-dependent cysteine proteolytic activity of CvaB, an ATP-binding cassette transporter.
Topics: Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Blotting, Western; Calcium; Calpain; Cell Division; Colicins; Culture Media; Cysteine; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Edetic Acid; Egtazic Acid; Escherichia coli Proteins; Ethylmaleimide; Histidine; Humans; Hydrogen-Ion Concentration; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Plasmids; Protease Inhibitors; Protein Binding; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Time Factors | 2004 |
Conserved cysteine and histidine residues in the putative zinc finger motif of the influenza A virus M1 protein are not critical for influenza virus replication.
Topics: Amino Acid Motifs; Amino Acid Sequence; Conserved Sequence; Cysteine; Histidine; Influenza A virus; Molecular Sequence Data; Structure-Activity Relationship; Viral Matrix Proteins; Virus Replication; Zinc Fingers | 2003 |
The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor.
Topics: Amino Acid Chloromethyl Ketones; Binding Sites; Coronavirus 3C Proteases; Crystallography, X-Ray; Cysteine; Cysteine Endopeptidases; Endopeptidases; Glutathione Transferase; Histidine; Hydrogen-Ion Concentration; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Severe acute respiratory syndrome-related coronavirus; Substrate Specificity; Time Factors; Viral Proteins | 2003 |
Lecithin retinol acyltransferase is a founder member of a novel family of enzymes.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalytic Domain; Conserved Sequence; Cysteine; Cysteine Endopeptidases; Glutamine; Histidine; Humans; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Phosphatidylcholine-Sterol O-Acyltransferase | 2003 |
Defining the bacteriophage T4 DNA packaging machine: evidence for a C-terminal DNA cleavage domain in the large terminase/packaging protein gp17.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Aspartic Acid; Bacteriophage T4; Binding Sites; Cysteine; DNA; Endodeoxyribonucleases; Histidine; Molecular Sequence Data; Mutation; Sequence Alignment; Viral Proteins | 2003 |
Chemical modification of catalytically essential functional groups of NAD-dependent hydrogenase from Ralstonia eutropha H16.
Topics: Cupriavidus necator; Cysteine; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Hydrogenase; Iodoacetamide; Kinetics; NAD | 2003 |
Role of His-16 in turnover of T4 pyrimidine dimer glycosylase.
Topics: Alanine; Aspartic Acid; Cell Survival; Cysteine; Dimerization; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Lysine; Models, Biological; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Phenotype; Plasmids; Serine; Time Factors; Ultraviolet Rays | 2004 |
DsbB elicits a red-shift of bound ubiquinone during the catalysis of DsbA oxidation.
Topics: Amino Acids; Bacterial Proteins; Binding Sites; Cell Membrane; Cysteine; Disulfides; Electron Transport; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Membrane Proteins; Models, Biological; Models, Chemical; Mutation; Oxidants; Oxidation-Reduction; Oxygen; Plasmids; Proline; Protein Disulfide-Isomerases; Spectrophotometry; Spheroplasts; Time Factors; Ubiquinone | 2004 |
Redox-dependent changes in RsrA, an anti-sigma factor in Streptomyces coelicolor: zinc release and disulfide bond formation.
Topics: Bacterial Proteins; Binding Sites; Cysteine; Disulfides; Histidine; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Conformation; Resorcinols; Streptomyces; Sulfhydryl Compounds; Surface Plasmon Resonance; Transcription Factors; Transcription, Genetic; Trypsin; Zinc | 2004 |
Purification, tandem mass characterization, and inhibition studies of oxidosqualene-lanosterol cyclase enzyme from bovine liver.
Topics: Amino Acid Sequence; Animals; Benzophenones; Cattle; Cysteine; Diethyl Pyrocarbonate; Dithionitrobenzoic Acid; Enzyme Inhibitors; Histidine; Hydrogen-Ion Concentration; Hydroxylamine; Inhibitory Concentration 50; Intramolecular Transferases; Kinetics; Mass Spectrometry; Microsomes, Liver; Molecular Sequence Data; Peptide Fragments; Sequence Analysis, Protein; Sequence Homology, Amino Acid | 2004 |
Crystallographic analysis of the interaction of nitric oxide with quaternary-T human hemoglobin.
Topics: Anaerobiosis; Crystallization; Crystallography, X-Ray; Cysteine; Heme; Hemoglobins; Histidine; Humans; Iron; Ligands; Nitric Oxide; Protein Conformation; Protein Structure, Quaternary; Protein Structure, Tertiary; Protein Subunits; Sulfhydryl Compounds | 2004 |
A novel copper site in a cyanobacterial metallochaperone.
Topics: Adenosine Triphosphatases; Amino Acid Substitution; ATP-Binding Cassette Transporters; Bacterial Proteins; Binding Sites; Carrier Proteins; Cation Transport Proteins; Copper; Cyanobacteria; Cysteine; Ferredoxins; Histidine; Ion Transport; Models, Molecular; Protein Folding | 2004 |
Architecture of NarGH reveals a structural classification of Mo-bisMGD enzymes.
Topics: Amino Acid Sequence; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; Electron Transport; Escherichia coli; Formate Dehydrogenases; Histidine; Models, Molecular; Molecular Sequence Data; Molybdenum; Nitrate Reductase; Nitrate Reductases; Proton-Motive Force; Static Electricity | 2004 |
Engineering a three-cysteine, one-histidine ligand environment into a new hyperthermophilic archaeal Rieske-type [2Fe-2S] ferredoxin from Sulfolobus solfataricus.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Cysteine; Electron Transport Complex III; Escherichia coli; Ferredoxins; Histidine; Iron-Sulfur Proteins; Ligands; Magnetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxygen; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Spectrometry, X-Ray Emission; Spectrum Analysis, Raman; Sulfolobus; Temperature; Thermodynamics; Ultraviolet Rays | 2004 |
Solution structure of a CCHHC domain of neural zinc finger factor-1 and its implications for DNA binding.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Cysteine; DNA; DNA Mutational Analysis; Histidine; Molecular Sequence Data; Nerve Tissue Proteins; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Rats; Thermodynamics; Trans-Activators; Zinc; Zinc Fingers | 2004 |
Enzymic characterization with progress curve analysis of a collagen peptidase from an enthomopathogenic bacterium, Photorhabdus luminescens.
Topics: Bradykinin; Chromatography, High Pressure Liquid; Collagen; Collagenases; Cysteine; Gelatin; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mass Spectrometry; Matrix Metalloproteinase Inhibitors; Metals; Photorhabdus; Protease Inhibitors; Software; Substrate Specificity | 2004 |
The distinct heme coordination environments and heme-binding stabilities of His39Ser and His39Cys mutants of cytochrome b5.
Topics: Animals; Cattle; Cysteine; Cytochromes b5; Electrophoresis, Polyacrylamide Gel; Heme; Histidine; Mass Spectrometry; Mutation; Protein Denaturation; Serine; Temperature | 2003 |
Chromophore selectivity in bacterial phytochromes: dissecting the process of chromophore attachment.
Topics: Amino Acid Substitution; Biliverdine; Binding Sites; Binding, Competitive; Cyanobacteria; Cysteine; Darkness; Dithioerythritol; Histidine; Kinetics; Oxidation-Reduction; Phycobilins; Phycocyanin; Phytochrome; Protein Binding; Pyrroles; Spectrophotometry; Tetrapyrroles | 2004 |
The biliverdin chromophore binds covalently to a conserved cysteine residue in the N-terminus of Agrobacterium phytochrome Agp1.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Bacterial Proteins; Biliverdine; Binding Sites; Conserved Sequence; Cysteine; Histidine; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phytochrome; Protein Binding; Rhizobium; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin | 2004 |
High prevalence of non-HFE gene-associated haemochromatosis in patients from southern Italy.
Topics: Adult; Aged; Case-Control Studies; Cysteine; Female; Gene Frequency; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; Homozygote; Humans; Italy; Male; Membrane Proteins; Middle Aged; Mutation; Prevalence | 2004 |
3C-like proteinase from SARS coronavirus catalyzes substrate hydrolysis by a general base mechanism.
Topics: Alanine; Amino Acid Substitution; Catalysis; Colorimetry; Coronavirus 3C Proteases; Cysteine; Cysteine Endopeptidases; Deuterium Exchange Measurement; Endopeptidases; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Serine; Severe acute respiratory syndrome-related coronavirus; Solvents; Substrate Specificity; Temperature; Thermodynamics; Viral Proteins | 2004 |
Metal ion affinities of the zinc finger domains of the metal responsive element-binding transcription factor-1 (MTF1).
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Cations, Divalent; Cobalt; Cysteine; DNA-Binding Proteins; Histidine; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Solubility; Transcription Factor MTF-1; Transcription Factors; Zinc; Zinc Fingers | 2004 |
Evidence for a proton transfer network and a required persulfide-bond-forming cysteine residue in Ni-containing carbon monoxide dehydrogenases.
Topics: Alanine; Aldehyde Oxidoreductases; Asparagine; Bacterial Proteins; Biological Transport; Catalysis; Clostridium; Cysteine; Electron Spin Resonance Spectroscopy; Histidine; Lysine; Multienzyme Complexes; Mutagenesis, Site-Directed; Nickel; Protons; Serine; Sulfides | 2004 |
Frequency of the C282Y and H63D mutations of the hemochromatosis gene (HFE) in 2501 ethnic Danes.
Topics: Aspartic Acid; Confidence Intervals; Cysteine; Denmark; Female; Gene Frequency; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Male; Membrane Proteins; Mutation; Tyrosine | 2004 |
HFE gene and hemochromatosis.
Topics: Aspartic Acid; Cysteine; Gene Frequency; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; Homozygote; Humans; Membrane Proteins; Mutation; Mutation, Missense; Tyrosine | 2004 |
Uniformly oriented bacterial F0F1-ATPase immobilized on a semi-permeable membrane: a step towards biotechnological energy transduction.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Substitution; Bacterial Proteins; Biotechnology; Biotinylation; Cysteine; Energy Transfer; Escherichia coli; Histidine; Luminescent Measurements; Membranes, Artificial; Phosphorus; Phosphorus Radioisotopes; Protein Subunits; Proton-Translocating ATPases; Recombinant Proteins | 2004 |
Identification of a nuclear export signal and protein interaction domains in deformed epidermal autoregulatory factor-1 (DEAF-1).
Topics: Active Transport, Cell Nucleus; Amino Acid Motifs; Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Cell Nucleus; Cysteine; Cytoplasm; DNA; DNA-Binding Proteins; Fatty Acids, Unsaturated; Glutathione Transferase; Histidine; Humans; Leucine; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Nuclear Localization Signals; Nuclear Proteins; Peptides; Plasmids; Precipitin Tests; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Transcription Factors; Transcription, Genetic; Transfection; Zinc | 2004 |
Potyviral NIa proteinase, a proteinase with novel deoxyribonuclease activity.
Topics: Aspartic Acid; Cell Nucleus; Cysteine; Cytoplasm; Deoxyribonucleases; DNA; DNA Mutational Analysis; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Escherichia coli; Glutathione Transferase; Green Fluorescent Proteins; Histidine; Hydrogen-Ion Concentration; Ions; Kinetics; Luminescent Proteins; Magnesium; Models, Molecular; Mutation; Plasmids; Point Mutation; Potyvirus; Recombinant Fusion Proteins; Recombinant Proteins; Sodium Chloride; Solanum tuberosum; Time Factors; Viral Proteins | 2004 |
PRMT3 is a ribosomal protein methyltransferase that affects the cellular levels of ribosomal subunits.
Topics: Amino Acid Motifs; Amino Acid Sequence; Cell Fractionation; Chromatography, Affinity; Cysteine; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Fungal Proteins; Genes, Fungal; Green Fluorescent Proteins; Histidine; Mass Spectrometry; Methyltransferases; Microscopy, Confocal; Molecular Sequence Data; Protein-Arginine N-Methyltransferases; Ribosomal Proteins; Ribosomes; RNA Processing, Post-Transcriptional; RNA, Ribosomal; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sequence Homology, Amino Acid; Subcellular Fractions; Zinc Fingers | 2004 |
The distinct functional properties of the nucleotide-binding domain of ATP7B, the human copper-transporting ATPase: analysis of the Wilson disease mutations E1064A, H1069Q, R1151H, and C1104F.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Arginine; Calorimetry; Cation Transport Proteins; Circular Dichroism; Copper-Transporting ATPases; Cysteine; Glutamic Acid; Histidine; Humans; Kinetics; Magnesium; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nucleotides; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Temperature | 2004 |
The structure and mechanism of serine acetyltransferase from Escherichia coli.
Topics: Acetylation; Acetyltransferases; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Escherichia coli; Histidine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Sequence Homology, Amino Acid; Serine O-Acetyltransferase | 2004 |
Development of a peptide reactivity assay for screening contact allergens.
Topics: Algorithms; Allergens; Amino Acids; Animals; Calibration; Chromatography, High Pressure Liquid; Cysteine; Dermatitis, Allergic Contact; Female; Glutathione; Histidine; Kinetics; Local Lymph Node Assay; Lysine; Mice; Mice, Inbred CBA; Peptides; Skin Tests; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 2004 |
The RING-H2-finger protein APC11 as a target of hydrogen peroxide.
Topics: Anaphase; Anaphase-Promoting Complex-Cyclosome; Animals; Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome; Catalysis; Catalytic Domain; Cell Culture Techniques; Cell Cycle; Cell Cycle Proteins; Cyclin B; Cyclin B1; Cysteine; Escherichia coli; Flow Cytometry; Free Radicals; HeLa Cells; Histidine; Humans; Hydrogen Peroxide; Immunoprecipitation; Ions; Mice; Miosis; Neoplasm Proteins; Nuclear Proteins; Oxidative Stress; Oxygen; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Securin; Sulfhydryl Compounds; Time Factors; Transfection; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligase Complexes; Zinc | 2004 |
The three-dimensional structure and X-ray sequence reveal that trichomaglin is a novel S-like ribonuclease.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Disulfides; Electrons; Histidine; Hydrogen-Ion Concentration; Ions; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; N-Glycosyl Hydrolases; Plant Proteins; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Ribonucleases; Ribosome Inactivating Proteins, Type 1; Sequence Homology, Amino Acid; Software | 2004 |
Cyanogen bromide cleavage generates fragments suitable for expressed protein and glycoprotein ligation.
Topics: Chromatography, Affinity; Cyanogen Bromide; Cysteine; Erythropoietin; Glycoproteins; Histidine; Peptide Fragments; Protein Engineering; Proteins | 2004 |
Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: crystal structure and mechanism.
Topics: Amino Acid Motifs; Amino Acid Sequence; Asparagine; Binding Sites; Catalysis; Cholesterol; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Dimerization; Escherichia coli; Histidine; Hydroxymethylglutaryl-CoA Synthase; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Protein Conformation; Sequence Homology, Amino Acid; Staphylococcus aureus | 2004 |
Hexa-histidin tag position influences disulfide structure but not binding behavior of in vitro folded N-terminal domain of rat corticotropin-releasing factor receptor type 2a.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Corticotropin-Releasing Hormone; Cysteine; Disulfides; Histidine; Molecular Sequence Data; Oligopeptides; Protein Binding; Protein Folding; Protein Structure, Tertiary; Rats; Receptors, Corticotropin-Releasing Hormone; Recombinant Proteins; Sequence Alignment; Urocortins | 2004 |
Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Arabidopsis; Binding Sites; Cations; Crystallography, X-Ray; Cysteine; Escherichia coli; Folic Acid; Fourier Analysis; Histidine; Homocysteine; Methionine; Methyltransferases; Models, Molecular; Plasmids; Protein Conformation; Protein Structure, Tertiary; Sulfur; Tetrahydrofolates; Vitamin B 12; Zinc | 2004 |
Identification of a zinc finger domain in the human NEIL2 (Nei-like-2) protein.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arginine; Blotting, Western; Circular Dichroism; Cysteine; DNA; DNA Glycosylases; DNA-(Apurinic or Apyrimidinic Site) Lyase; Escherichia coli; Histidine; Humans; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oxygen; Peptides; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Uracil; Zinc; Zinc Fingers | 2004 |
Overexpression of human transforming growth factor-beta1 using a recombinant CHO cell expression system.
Topics: Animals; Biochemistry; Blotting, Western; Cell Culture Techniques; Cell Line; CHO Cells; Cricetinae; Cysteine; Disulfides; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Histidine; Humans; Mass Spectrometry; Models, Biological; Plasmids; Protein Binding; Protein Sorting Signals; Rats; Recombinant Proteins; Serum Albumin; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Mapping protein-protein interactions between MutL and MutH by cross-linking.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Base Pair Mismatch; Binding Sites; Cross-Linking Reagents; Cysteine; Dimerization; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Genetic Complementation Test; Histidine; Light; Mass Spectrometry; Models, Chemical; Models, Molecular; Models, Statistical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; MutL Proteins; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Trypsin | 2004 |
Cytochrome c550 in the cyanobacterium Thermosynechococcus elongatus: study of redox mutants.
Topics: Calcium; Chlorine; Cloning, Molecular; Cyanobacteria; Cysteine; Cytochrome c Group; DNA; Electron Spin Resonance Spectroscopy; Heme; Histidine; Hot Temperature; Ligands; Methionine; Models, Genetic; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Oxygen; Plasmids; Point Mutation; Polymerase Chain Reaction; Synechocystis; Temperature; Thylakoids; Time Factors | 2004 |
Raptor protein contains a caspase-like domain.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Motifs; Amino Acid Sequence; Animals; Caspases; Catalysis; Cysteine; Histidine; Humans; Molecular Sequence Data; Peptide Hydrolases; Proteins; Regulatory-Associated Protein of mTOR; Sequence Homology, Amino Acid; Signal Transduction; Sirolimus | 2004 |
ECEPE proteins: a novel family of eukaryotic cysteine proteinases.
Topics: Amino Acid Sequence; Aspartic Acid; Catalysis; Cysteine; Cysteine Endopeptidases; Eukaryotic Cells; Glutamine; Guanylate Cyclase; Histidine; Molecular Sequence Data; Papain; Sequence Homology, Amino Acid | 2004 |
Reversible and nonoxidative gamma-resorcylic acid decarboxylase: characterization and gene cloning of a novel enzyme catalyzing carboxylation of resorcinol, 1,3-dihydroxybenzene, from Rhizobium radiobacter.
Topics: Agrobacterium tumefaciens; Aspergillus niger; Binding Sites; Carbon-Carbon Ligases; Carboxy-Lyases; Carboxylic Acids; Catalysis; Catechols; Cell-Free System; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cloning, Molecular; Cysteine; Dimerization; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Hydroxybenzoates; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Oxygen; Resorcinols; Sphingomonas; Temperature; Tretinoin | 2004 |
Coupled sodium/glucose cotransport by SGLT1 requires a negative charge at position 454.
Topics: Animals; Aspartic Acid; Cell Membrane; Cysteine; Glucose; Histidine; Humans; Membrane Glycoproteins; Methylglucosides; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Binding; Rhodamines; Sodium; Sodium-Glucose Transporter 1; Spectrometry, Fluorescence; Xenopus laevis | 2004 |
Polyprotein cleavage mechanism of SARS CoV Mpro and chemical modification of the octapeptide.
Topics: Amino Acid Sequence; Binding Sites; Computer Simulation; Coronavirus 3C Proteases; Cysteine; Cysteine Endopeptidases; Drug Design; Glutamine; Histidine; Hydrogen Bonding; Models, Molecular; Molecular Biology; Molecular Structure; Peptides; Protein Conformation; Protein Structure, Tertiary; Quantum Theory; Serine; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Static Electricity | 2004 |
Cys-His proteases are among the wired proteins of the cell.
Topics: Animals; Binding Sites; Biophysics; Cathepsin B; Cattle; Copper; Cysteine; Cystine; Dithiothreitol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Histidine; Hydrogen-Ion Concentration; Ions; Iron; Lysosomes; Models, Biological; Models, Molecular; Oxidation-Reduction; Oxygen; Peptide Hydrolases; Protein Binding; Protons; Spleen; Time Factors; Zinc | 2004 |
A genetically encoded photocaged amino acid.
Topics: Base Sequence; Caprylates; Cysteine; Histidine; Humans; Leucine-tRNA Ligase; Methyltyrosines; Models, Molecular; Molecular Sequence Data; Mutagenesis; Nucleic Acid Conformation; Photochemistry; Proteins; RNA, Transfer, Amino Acyl; Superoxide Dismutase | 2004 |
Spectroscopic identification of different types of copper centers generated in synthetic four-helix bundle proteins.
Topics: Amino Acid Sequence; Binding Sites; Cations, Divalent; Chromatography, Gel; Circular Dichroism; Combinatorial Chemistry Techniques; Copper; Cysteine; Electron Spin Resonance Spectroscopy; Histidine; Metalloproteins; Metals; Models, Molecular; Protein Structure, Quaternary; Spectrophotometry, Ultraviolet | 2004 |
Solution NMR structure of the iron-sulfur cluster assembly protein U (IscU) with zinc bound at the active site.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Chelating Agents; Conserved Sequence; Cysteine; Evolution, Molecular; Haemophilus influenzae; Histidine; Hydrogen Bonding; Iron-Sulfur Proteins; Ligands; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Solutions; Spectrum Analysis, Raman; Zinc | 2004 |
Creation and characteristics of unnatural CysHis(3)-type zinc finger protein.
Topics: Amino Acid Sequence; Base Composition; Base Sequence; Binding Sites; Circular Dichroism; Cysteine; Electrophoretic Mobility Shift Assay; Histidine; Hydrolysis; Kinetics; Molecular Sequence Data; Nitrophenols; Peptide Fragments; Protein Structure, Tertiary; Sp1 Transcription Factor; Spectrophotometry, Ultraviolet; Zinc Fingers | 2004 |
Crystallography of the integral membrane protein EmrE from Escherichia coli.
Topics: Antiporters; Crystallography, X-Ray; Cysteine; Drug Resistance, Multiple; Escherichia coli; Escherichia coli Proteins; Histidine; Membrane Proteins; Models, Molecular; Mutation; Polymerase Chain Reaction; Protein Conformation | 2004 |
Mechanism of hydrogen peroxide-induced Cu,Zn-superoxide dismutase-centered radical formation as explored by immuno-spin trapping: the role of copper- and carbonate radical anion-mediated oxidations.
Topics: Animals; Anions; Binding Sites; Blotting, Western; Carbon; Catalase; Cattle; Copper; Cysteine; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Free Radicals; Histidine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Models, Chemical; Oxidants; Oxidation-Reduction; Oxygen; Pentetic Acid; Spin Trapping; Superoxide Dismutase; Superoxides; Time Factors; Tyrosine | 2005 |
Heterologous expression, purification, and characterization of recombinant rat cysteine dioxygenase.
Topics: Animals; Catalysis; Chromatography, High Pressure Liquid; Cysteine; Cysteine Dioxygenase; Dioxygenases; DNA, Complementary; Escherichia coli; Histidine; Homocysteine; Hydrogen-Ion Concentration; Iron; Kinetics; Models, Chemical; Open Reading Frames; Oxygen; Protein Structure, Tertiary; Rats; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Temperature; Time Factors | 2005 |
Complete reversal of coenzyme specificity of xylitol dehydrogenase and increase of thermostability by the introduction of structural zinc.
Topics: Amino Acid Sequence; Blotting, Western; Catalysis; Cloning, Molecular; Cysteine; D-Xylulose Reductase; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Ethanol; Fermentation; Histidine; Hot Temperature; Immunoblotting; Kinetics; Ligands; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NAD; NADP; Pichia; Protein Structure, Tertiary; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Spectrophotometry; Substrate Specificity; Sugar Alcohol Dehydrogenases; Temperature; Time Factors; Xylose; Zinc | 2005 |
Abolition of oxygenase function, retention of NADPH oxidase activity, and emergence of peroxidase activity upon replacement of the axial cysteine-436 ligand by histidine in cytochrome P450 2B4.
Topics: Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Base Sequence; Catalytic Domain; Chromatography, High Pressure Liquid; Cysteine; Cytochrome P450 Family 2; DNA, Complementary; Escherichia coli; Heme; Histidine; Hydrogen Peroxide; In Vitro Techniques; Ligands; Molecular Weight; Mutagenesis, Site-Directed; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry | 2005 |
Cys redox reactions and metal binding of a Cys2His2 zinc finger.
Topics: Amino Acid Sequence; Binding Sites; Cadmium; Cysteine; Histidine; Hydrogen Peroxide; Hydrogen-Ion Concentration; In Vitro Techniques; Lead; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Sp1 Transcription Factor; Spectrometry, Mass, Electrospray Ionization; Zinc; Zinc Fingers | 2005 |
Heavy metals modulate the activity of the purinergic P2X4 receptor.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; Extracellular Fluid; Histidine; Metals, Heavy; Mutation; Oocytes; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Toxicity Tests; Xenopus laevis | 2005 |
Energetics of proton transfer pathways in reaction centers from Rhodobacter sphaeroides. The Glu-H173 activated mutants.
Topics: Alanine; Cysteine; Cytoplasm; Electron Transport; Electrons; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Models, Molecular; Mutation; Nitrogen; Oxidation-Reduction; Oxygen; Protons; Rhodobacter sphaeroides; Software | 2005 |
Attachment of a histidine tag to the minimal zinc finger protein of the Aspergillus nidulans gene regulatory protein AreA causes a conformational change at the DNA-binding site.
Topics: Amino Acid Sequence; Aspergillus nidulans; Binding Sites; Cysteine; Fungal Proteins; Gene Expression Regulation, Fungal; Genetic Vectors; Histidine; Kinetics; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Denaturation; Protein Structure, Tertiary; Spectrometry, Fluorescence; Thrombin; Tryptophan; Urea; Zinc Fingers | 2005 |
Comparative evaluation of two purification methods of anti-CD19-c-myc-His6-Cys scFv.
Topics: Antibodies, Monoclonal; Antigens, CD19; Blotting, Western; Chelating Agents; Chromatography, Affinity; Chromatography, Agarose; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Flow Cytometry; Histidine; Hybridomas; Hydrogen-Ion Concentration; Immunoglobulin Variable Region; Ion Exchange Resins; Mass Spectrometry; Molecular Weight; Nickel; Nitrilotriacetic Acid; Plasmids; Proto-Oncogene Proteins c-myc; Solubility; Temperature; Thiogalactosides | 2005 |
How to hide zinc in a small protein.
Topics: Amino Acid Sequence; Bacteria; Cadmium; Cysteine; Dimerization; Histidine; Ligands; Lysine; Metallothionein; Molecular Sequence Data; Protein Binding; Protein Folding; Proteins; Sequence Alignment; Sulfhydryl Compounds; Sulfides; Zinc; Zinc Compounds; Zinc Fingers | 2005 |
Enzymatic activity characterization of SARS coronavirus 3C-like protease by fluorescence resonance energy transfer technique.
Topics: Alanine; Amino Acid Substitution; Coronavirus 3C Proteases; Cysteine; Cysteine Endopeptidases; Endopeptidases; Fluorescence Resonance Energy Transfer; Histidine; Hydrogen-Ion Concentration; Kinetics; Methionine; Mutagenesis, Site-Directed; Severe acute respiratory syndrome-related coronavirus; Substrate Specificity; Temperature; Viral Proteins | 2005 |
Analysis of allosteric signal transduction mechanisms in an engineered fluorescent maltose biosensor.
Topics: Allosteric Site; Biosensing Techniques; Carrier Proteins; Cysteine; Escherichia coli; Genes, Reporter; Histidine; Ligands; Maltose; Maltose-Binding Proteins; Microscopy, Fluorescence; Models, Molecular; Mutation; Protein Conformation; Protein Engineering; Signal Transduction; Software; Spectrometry, Fluorescence | 2005 |
Contributions of cysteine residues in Zn2 to zinc fingers and thiol-disulfide oxidoreductase activities of chaperone DnaJ.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Catalysis; Cysteine; Escherichia coli Proteins; Heat-Shock Proteins; Histidine; HSP40 Heat-Shock Proteins; Molecular Chaperones; Molecular Sequence Data; Peptide Fragments; Protein Conformation; Protein Disulfide Reductase (Glutathione); Protein Structure, Tertiary; Serine; Zinc; Zinc Fingers | 2005 |
Conservation of cysteine residues in fungal histidine acid phytases.
Topics: 6-Phytase; Acid Phosphatase; Amino Acid Sequence; Aspergillus fumigatus; Aspergillus niger; Conserved Sequence; Cysteine; Disulfides; Histidine; Molecular Sequence Data; Sequence Alignment; Sequence Analysis, Protein; Sequence Homology, Amino Acid | 2005 |
Identification of the putative staphylococcal AgrB catalytic residues involving the proteolytic cleavage of AgrD to generate autoinducing peptide.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Blotting, Western; Catalytic Domain; Cell Membrane; Conserved Sequence; Cysteine; Cytoplasm; DNA Mutational Analysis; DNA Primers; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Escherichia coli; Green Fluorescent Proteins; Histidine; Molecular Sequence Data; Mutation; Peptides; Peptides, Cyclic; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Software; Staphylococcus aureus; Temperature; Time Factors | 2005 |
The conserved histidine 295 does not contribute to proton cotransport by the glutamate transporter EAAC1.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Animals; Biological Transport, Active; Cell Line; Conserved Sequence; Cysteine; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Chemical; Patch-Clamp Techniques; Protons; Rats; Symporters; Transfection | 2005 |
Functional consequences of progressive cone dystrophy-associated mutations in the human cone photoreceptor cyclic nucleotide-gated channel CNGA3 subunit.
Topics: Animals; Arginine; Cyclic Nucleotide-Gated Cation Channels; Cysteine; Disease Progression; Electrophysiology; Female; Histidine; Humans; Ion Channel Gating; Ion Channels; Mutation; Oocytes; Patch-Clamp Techniques; Protein Isoforms; Retinal Cone Photoreceptor Cells; Retinal Diseases; Xenopus laevis | 2005 |
Crystal structure of S-ribosylhomocysteinase (LuxS) in complex with a catalytic 2-ketone intermediate.
Topics: Alanine; Arginine; Bacillus subtilis; Bacterial Proteins; Binding Sites; Carbon-Sulfur Lyases; Catalysis; Cobalt; Crystallization; Crystallography, X-Ray; Cysteine; Ferrous Compounds; Histidine; Homocysteine; Hydrolases; Ketones; Models, Molecular; Mutagenesis, Site-Directed; Serine; Spectrophotometry, Ultraviolet; Substrate Specificity; Vibrio | 2005 |
Mutant-selective thyromimetics for the chemical rescue of thyroid hormone receptor mutants associated with resistance to thyroid hormone.
Topics: Acetates; Arginine; Carboxylic Acids; Cell Line; Cysteine; Drug Resistance; Glycine; Histidine; Humans; Ligands; Molecular Mimicry; Mutagenesis, Site-Directed; Phenols; Promoter Regions, Genetic; Protein Binding; Receptors, Thyroid Hormone; Repetitive Sequences, Nucleic Acid; Response Elements; Thyroid Hormone Receptors beta; Thyrotropin; Triiodothyronine | 2005 |
Site-directed mutagenesis of active site residues of phosphite dehydrogenase.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Cysteine; Deuterium Exchange Measurement; Diethyl Pyrocarbonate; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; Phosphites; Sequence Alignment | 2005 |
Zn protein simulations including charge transfer and local polarization effects.
Topics: Binding Sites; Cations, Divalent; Computer Simulation; Cysteine; Histidine; Metalloproteins; Models, Molecular; Oligopeptides; Protein Conformation; Thermodynamics; Zinc; Zinc Fingers | 2005 |
CO-dependent activity-controlling mechanism of heme-containing CO-sensor protein, neuronal PAS domain protein 2.
Topics: Amino Acid Sequence; Animals; Basic Helix-Loop-Helix Transcription Factors; Carbon Monoxide; Cysteine; Cytochrome c Group; Dimerization; DNA; Heme; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Iron; Ligands; Liver; Mice; Mice, Inbred C57BL; Models, Chemical; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Neurons; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protons; Sequence Homology, Amino Acid; Signal Transduction; Spectrum Analysis, Raman; Time Factors; Transcription Factors | 2005 |
Carbohydrate-appended 2,2'-dipicolylamine metal complexes as potential imaging agents.
Topics: Amines; Carbohydrates; Crystallography, X-Ray; Cysteine; Diagnostic Imaging; Ethylenes; Histidine; Isotope Labeling; Ligands; Organometallic Compounds; Picolinic Acids; Radiopharmaceuticals; Time Factors | 2005 |
Hyperthermal stability of neuroglobin and cytoglobin.
Topics: Animals; Circular Dichroism; Cyanides; Cysteine; Cytoglobin; Disulfides; Drosophila melanogaster; Globins; Histidine; Humans; Kinetics; Ligands; Models, Molecular; Nerve Tissue Proteins; Neuroglobin; Protein Denaturation; Temperature; Thermodynamics | 2005 |
Mutation of Cys105 inhibits dimerization of p12CDK2-AP1 and its growth suppressor effect.
Topics: Alanine; Animals; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cysteine; Cytoplasm; Dimerization; Diploidy; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Glutathione Transferase; Histidine; Humans; Keratinocytes; Mice; Microscopy, Confocal; Mink; Mutation; Protein Kinases; Recombinant Fusion Proteins; RNA, Small Interfering; Time Factors; Transfection; Tumor Suppressor Proteins | 2005 |
The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity.
Topics: Amino Acid Motifs; Animals; Apoptosis Regulatory Proteins; Binding Sites; Caenorhabditis elegans; Chelating Agents; Cysteine; Databases, Genetic; DNA; DNA-Binding Proteins; Histidine; Humans; Mutagenesis, Site-Directed; Mutation; Nuclear Proteins; Phenanthrolines; Plasmids; Protein Binding; Protein Structure, Tertiary; Transcription, Genetic; Zebrafish; Zinc; Zinc Fingers | 2005 |
Preferred mexiletine block of human sodium channels with IVS4 mutations and its pH-dependence.
Topics: Anti-Arrhythmia Agents; Cell Line; Cysteine; Exercise; Histidine; Humans; Hydrogen-Ion Concentration; Mexiletine; Mutation; Myotonic Disorders; Paralysis; Patch-Clamp Techniques; Pharmacogenetics; Sodium Channels; Time Factors; Transfection | 2005 |
Mechanism of zinc coordination by point-mutated structures of the distal CCHC binding motif of the HIV-1 NCp7 protein.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Capsid Proteins; Cysteine; gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; Histidine; HIV-1; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Molecular Sequence Data; Peptide Fragments; Point Mutation; Protein Binding; Serine; Spectrometry, Fluorescence; Viral Proteins; Zinc | 2005 |
Susceptibility of actin to modification by 4-hydroxy-2-nonenal.
Topics: Actins; Albumins; Aldehydes; Animals; Antibodies, Monoclonal; Blotting, Western; Cysteine; Ferric Compounds; Glyceraldehyde-3-Phosphate Dehydrogenases; Hemocyanins; Histidine; Kidney; Kidney Neoplasms; Lysine; Male; Metallothionein; Nitrilotriacetic Acid; Rats; Rats, Wistar; Specific Pathogen-Free Organisms; Superoxide Dismutase | 2005 |
Structural insights into the mechanism of nuclease A, a betabeta alpha metal nuclease from Anabaena.
Topics: Amino Acid Motifs; Amino Acid Sequence; Anabaena; Arginine; Binding Sites; Catalysis; Catalytic Domain; Cations; Crystallography, X-Ray; Cysteine; Dimerization; Disulfides; DNA; DNA Mutational Analysis; Endonucleases; Escherichia coli; Histidine; Hydrolysis; Ions; Manganese; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxygen; Protein Folding; Protein Sorting Signals; Protein Structure, Tertiary; Recombinant Proteins; RNA; Sequence Homology, Amino Acid; Serratia; Static Electricity; Zinc | 2005 |
An intersubunit zinc binding site in rat P2X2 receptors.
Topics: Adenosine Triphosphate; Allosteric Site; Animals; Binding Sites; Blotting, Western; Cell Membrane; Cysteine; Dimerization; Disulfides; Dithiothreitol; DNA, Complementary; Dose-Response Relationship, Drug; Histidine; Humans; Ions; Ligands; Mesylates; Models, Biological; Mutagenesis, Site-Directed; Mutation; Oocytes; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Sulfhydryl Reagents; Xenopus; Zinc | 2005 |
Molybdenum cofactor biosynthesis in humans: identification of a persulfide group in the rhodanese-like domain of MOCS3 by mass spectrometry.
Topics: Amino Acid Sequence; Animals; Coenzymes; Cysteine; Disulfides; Histidine; Humans; Metalloproteins; Mice; Molecular Sequence Data; Molybdenum Cofactors; Mutagenesis, Site-Directed; Nucleotidyltransferases; Peptide Mapping; Protein Structure, Tertiary; Pteridines; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds; Sulfides; Sulfurtransferases; Thiosulfate Sulfurtransferase | 2005 |
LC-ESI-MS/MS determination of 4-hydroxy-trans-2-nonenal Michael adducts with cysteine and histidine-containing peptides as early markers of oxidative stress in excitable tissues.
Topics: Aldehydes; Animals; Biomarkers; Chromatography, Liquid; Cysteine; Histidine; Male; Muscle, Skeletal; Oxidative Stress; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2005 |
Amino acid residues associated with enzymatic activities of the isomerizing phycoviolobilin-lyase PecE/F.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Bacterial Proteins; Binding Sites; Cyanobacteria; Cysteine; Enzyme Activation; Histidine; Isomerism; Kinetics; Lyases; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phycobilins; Phycocyanin; Protein Subunits; Pyrroles; Sequence Deletion; Tetrapyrroles; Tryptophan | 2005 |
High- and low-affinity binding of S-citalopram to the human serotonin transporter mutated at 20 putatively important amino acid positions.
Topics: Amino Acids; Animals; Binding Sites; Binding, Competitive; Chlorocebus aethiops; Citalopram; COS Cells; Cysteine; Dose-Response Relationship, Drug; Half-Life; Histidine; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Mutagenesis; Mutation; Nerve Tissue Proteins; Protein Binding; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Time Factors; Transfection; Tritium | 2005 |
Molecular modeling and site-directed mutagenesis of plant chloroplast monogalactosyldiacylglycerol synthase reveal critical residues for activity.
Topics: Amino Acid Sequence; Binding Sites; Cations; Chloroplasts; Chromatography; Crystallography, X-Ray; Cysteine; Detergents; Dimerization; Durapatite; Escherichia coli; Galactosyltransferases; Gene Expression Regulation, Plant; Genetic Vectors; Glycosyltransferases; Histidine; Hydrogen Bonding; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleotides; Phylogeny; Point Mutation; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Spinacia oleracea | 2005 |
Involvement of heme regulatory motif in heme-mediated ubiquitination and degradation of IRP2.
Topics: Amino Acid Motifs; Cell Line, Tumor; Cysteine; Heme; Histidine; Humans; Iron; Iron Regulatory Protein 2; Ubiquitin | 2005 |
Functional dissection of a mercuric ion transporter, MerC, from Acidithiobacillus ferrooxidans.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Cation Transport Proteins; Cysteine; Dimerization; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Hydrophobic and Hydrophilic Interactions; Mercury; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oxidoreductases; Plasmids; Protein Binding; Recombinant Proteins; Saccharomyces cerevisiae; Two-Hybrid System Techniques | 2005 |
Characterization of an Escherichia coli sulfite oxidase homologue reveals the role of a conserved active site cysteine in assembly and function.
Topics: Binding Sites; Computational Biology; Conserved Sequence; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli Proteins; Histidine; Mutagenesis, Site-Directed; Oligopeptides; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Protein Processing, Post-Translational; Serine; Structural Homology, Protein; Substrate Specificity; Tungsten | 2005 |
4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal.
Topics: Aldehydes; Butylamines; Cell Line; Cell Survival; Cysteine; Cysteine Proteinase Inhibitors; Histidine; Humans; Immunohistochemistry; Indicators and Reagents; Kinetics; Lysine; Neurons; Neurotoxicity Syndromes; Oxidative Stress; Proteins; Schiff Bases; Spectrophotometry, Ultraviolet | 2005 |
Direct interaction of multidrug efflux transporter AcrB and outer membrane channel TolC detected via site-directed disulfide cross-linking.
Topics: Amino Acid Substitution; Bacterial Outer Membrane Proteins; Carrier Proteins; Cell Membrane; Cysteine; Disulfides; Drug Tolerance; Escherichia coli; Escherichia coli Proteins; Gene Expression; Histidine; Membrane Proteins; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Multiprotein Complexes; Point Mutation; Protein Binding; Protein Structure, Quaternary; Protein Structure, Secondary | 2005 |
Characterization of expression and stability of recombinant cystein-rich protein human MT1A from yeast.
Topics: Carbon; Chlorides; Cysteine; Gene Expression; Hemolysis; Histidine; Humans; Metallothionein; Recombinant Proteins; Saccharomyces cerevisiae; Zinc Compounds | 2005 |
Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Brain; Catalysis; Catalytic Domain; Cattle; Chlorocebus aethiops; Chromatography; COS Cells; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Immunoblotting; Kidney; Lysosomes; Macrophages; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Open Reading Frames; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Phospholipids; Plasmids; Pulmonary Surfactants; Rats; Sequence Homology, Amino Acid; Serine; Surface-Active Agents; Transfection | 2005 |
Absorption and emission spectroscopic characterisation of combined wildtype LOV1-LOV2 domain of phot from Chlamydomonas reinhardtii.
Topics: Abstracting and Indexing; Animals; Carrier Proteins; Chlamydomonas reinhardtii; Cryptochromes; Cysteine; Flavin Mononucleotide; Flavoproteins; Fluorescence Polarization; Histidine; Maltose-Binding Proteins; Photoreceptors, Microbial; Protein Structure, Tertiary; Recombinant Fusion Proteins; Riboflavin; Spectrometry, Fluorescence; Spectrophotometry | 2005 |
Localization of a substrate binding domain of the human reduced folate carrier to transmembrane domain 11 by radioaffinity labeling and cysteine-substituted accessibility methods.
Topics: Amino Acid Sequence; Anions; Aspartic Acid; Blotting, Western; Cell Line; Cell Membrane; Cysteine; Cytosol; Folic Acid; Glutamine; HeLa Cells; Histidine; Humans; K562 Cells; Leucovorin; Membrane Transport Proteins; Mesylates; Microscopy, Fluorescence; Molecular Sequence Data; Mutagenesis; Mutation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Reduced Folate Carrier Protein; Sulfhydryl Reagents; Temperature; Thiocyanates; Time Factors; Transfection; Tyrosine | 2005 |
Human mitochondrial ClpP is a stable heptamer that assembles into a tetradecamer in the presence of ClpX.
Topics: Adenosine Triphosphate; Allosteric Site; Animals; Binding Sites; Chromatin Immunoprecipitation; Chromatography, Gel; Cross-Linking Reagents; Cysteine; Dimerization; Disulfides; Endopeptidase Clp; Glutaral; Green Fluorescent Proteins; Histidine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Liver; Microscopy, Electron; Mitochondria; Mutagenesis; Mutation; Peptide Hydrolases; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Recombinant Proteins; Time Factors; Trypsin; Ultracentrifugation | 2005 |
A mammalian actin substitution in yeast actin (H372R) causes a suppressible mitochondria/vacuole phenotype.
Topics: Actins; Allosteric Site; Arginine; Carbon; Crystallography, X-Ray; Cysteine; Cytoskeleton; Glucose; Glycerol; Green Fluorescent Proteins; Histidine; Maleimides; Microscopy, Fluorescence; Mitochondria; Models, Molecular; Muscle, Skeletal; Muscles; Mutagenesis; Mutation; Phenotype; Polymers; Protein Conformation; Protein Structure, Tertiary; Pyrenes; Saccharomyces cerevisiae; Temperature; Time Factors; Vacuoles | 2005 |
Kinetic comparison of procaspase-3 and caspase-3.
Topics: Binding Sites; Caspase 3; Caspases; Catalysis; Crystallography, X-Ray; Cysteine; Diethyl Pyrocarbonate; Enzyme Activation; Enzyme Precursors; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics; Mutation | 2005 |
Crystal structure of glucooligosaccharide oxidase from Acremonium strictum: a novel flavinylation of 6-S-cysteinyl, 8alpha-N1-histidyl FAD.
Topics: Acremonium; Alcohol Oxidoreductases; Amino Acid Sequence; Binding Sites; Carbon; Cellobiose; Crystallography, X-Ray; Cysteine; Dimerization; Disaccharides; Electrons; Evolution, Molecular; Flavins; Glucose; Histidine; Ions; Kinetics; Lactose; Maltose; Models, Chemical; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Oligosaccharides; Oxidoreductases; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid | 2005 |
Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease.
Topics: Aspartic Acid; Binding Sites; Coenzyme A; Crystallization; Crystallography, X-Ray; Cysteine; Escherichia coli; Ferrous Compounds; Histidine; Humans; Ketoglutaric Acids; Mixed Function Oxygenases; Models, Molecular; Mutation; Peroxisomes; Phytanic Acid; Protein Binding; Protein Structure, Secondary; Recombinant Proteins; Refsum Disease; Structure-Activity Relationship; Transfection | 2005 |
Development and characterization of green fluorescent protein mutants with altered lifetimes.
Topics: Animals; Biochemistry; Cysteine; Genetic Techniques; Green Fluorescent Proteins; Histidine; Hydrozoa; Microscopy, Fluorescence; Models, Chemical; Mutation; Plasmids; Polymerase Chain Reaction; Spectrophotometry; Time Factors; Ultraviolet Rays | 2005 |
Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1.
Topics: Ascorbic Acid; Base Sequence; Cell Line; Cysteine; DNA Primers; Glutathione; Glycolysis; Histidine; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Oxaloacetic Acid; Procollagen-Proline Dioxygenase; Pyruvic Acid | 2005 |
Lineage-specific variations of congruent evolution among DNA sequences from three genomes, and relaxed selective constraints on rbcL in Cryptomonas (Cryptophyceae).
Topics: Asparagine; Aspartic Acid; Bayes Theorem; Codon; Cryptophyta; Cysteine; DNA; DNA, Ribosomal; Evolution, Molecular; Genome; Histidine; Likelihood Functions; Phenylalanine; Photosynthesis; Phylogeny; Plastids; Polymerase Chain Reaction; Ribulose-Bisphosphate Carboxylase; Sequence Analysis, DNA; Tyrosine | 2005 |
Neurons inflict self-harm.
Topics: Cysteine; Dopamine; Histidine; Models, Biological; Mutation; Neurons; Neuroprotective Agents; Parkinson Disease; Protein Folding; Protein Structure, Tertiary; Solubility; Substantia Nigra; Ubiquitin-Protein Ligases | 2005 |
Cys(x)His(y)-Zn2+ interactions: possibilities and limitations of a simple pairwise force field.
Topics: Computer Simulation; Cysteine; Histidine; Ligands; Models, Chemical; Molecular Structure; Protons; Thermodynamics; Zinc | 2006 |
The cysteine-desulfurase IscS promotes the production of the rhodanese RhdA in the persulfurated form.
Topics: Azotobacter vinelandii; Carbon-Sulfur Lyases; Catalytic Domain; Cysteine; Escherichia coli; Histidine; Peptide Mapping; Protein Structure, Tertiary; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfhydryl Compounds; Sulfur; Thiosulfate Sulfurtransferase | 2005 |
Mechanism of metal ion activation of the diphtheria toxin repressor DtxR.
Topics: Bacterial Proteins; Binding Sites; Calorimetry; Corynebacterium diphtheriae; Crystallography, X-Ray; Cysteine; DNA-Binding Proteins; Histidine; Ligands; Nickel; Protein Denaturation; Protein Folding; Temperature | 2005 |
Mechanisms of aurothiomalate-Cys2His2 zinc finger interactions.
Topics: Amino Acid Sequence; Animals; Circular Dichroism; Cysteine; Gold Sodium Thiomalate; Histidine; Humans; Molecular Sequence Data; Spectrometry, Mass, Electrospray Ionization; Transcription Factor TFIIIA; Xenopus; Zinc Fingers | 2005 |
Molecular characterization of the mercurial sensitivity of a frog urea transporter (fUT).
Topics: Amino Acid Sequence; Animals; Cysteine; Female; Gene Expression; Histidine; Membrane Transport Proteins; Mercuric Chloride; Mercury Compounds; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Point Mutation; Recombinant Proteins; RNA, Complementary; Structure-Activity Relationship; Transfection; Urea; Urea Transporters; Xenopus laevis | 2006 |
Regulation of sexual dimorphism: mutational and chemogenetic analysis of the doublesex DM domain.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Cysteine; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Enhancer Elements, Genetic; Female; Histidine; Male; Models, Molecular; Molecular Sequence Data; Mutagenesis; Protein Folding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sex Characteristics; Zinc | 2006 |
Characterization of the Desulfovibrio desulfuricans ATCC 27774 DsrMKJOP complex--a membrane-bound redox complex involved in the sulfate respiratory pathway.
Topics: Bacterial Proteins; Catalysis; Cysteine; Cytochrome c Group; Desulfovibrio desulfuricans; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Genomics; Heme; Histidine; Iron-Sulfur Proteins; Membranes; Methionine; Oxidation-Reduction; Respiratory System; Spectrophotometry, Ultraviolet; Sulfates | 2006 |
HIV-1 Tat is a natively unfolded protein: the solution conformation and dynamics of reduced HIV-1 Tat-(1-72) by NMR spectroscopy.
Topics: Computer Simulation; Cysteine; Enzyme Inhibitors; Freeze Drying; Gene Products, tat; Histidine; HIV-1; Humans; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peptide Fragments; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Sodium Azide; Solutions; tat Gene Products, Human Immunodeficiency Virus; Temperature | 2006 |
Linker chains of the gigantic hemoglobin of the earthworm Lumbricus terrestris: primary structures of linkers L2, L3, and L4 and analysis of the connectivity of the disulfide bonds in linker L1.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Binding Sites; Calcium; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Dithiothreitol; DNA, Complementary; Glutamic Acid; Heme; Hemoglobins; Histidine; Humans; Ligands; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Oligochaeta; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Receptors, LDL; RNA, Messenger; Sequence Homology, Amino Acid; Sodium Dodecyl Sulfate; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase | 2006 |
GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Analgesics, Non-Narcotic; Animals; Blotting, Western; Brain; Cell Membrane; CHO Cells; Cricetinae; Cysteine; DNA, Complementary; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Estrogens; Ethylmaleimide; Flow Cytometry; Gene Expression Regulation; Glutathione Transferase; Glycoside Hydrolases; Glycosylation; Golgi Apparatus; Histidine; Humans; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Kinetics; Methionine; Microscopy, Fluorescence; Microtubule-Associated Proteins; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Opioid, kappa; Recombinant Fusion Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Signal Transduction; Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins; Time Factors; Transfection; Tubulin; Two-Hybrid System Techniques | 2006 |
Exploring the recognition of quadruplex DNA by an engineered Cys2-His2 zinc finger protein.
Topics: Cysteine; DNA; Early Growth Response Protein 1; Enzyme-Linked Immunosorbent Assay; G-Quadruplexes; Histidine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Protein Conformation; Protein Engineering; Protein Structure, Tertiary; Recombinant Proteins; Surface Plasmon Resonance; Zinc Fingers | 2006 |
Chromophore attachment to phycobiliprotein beta-subunits: phycocyanobilin:cysteine-beta84 phycobiliprotein lyase activity of CpeS-like protein from Anabaena Sp. PCC7120.
Topics: Anabaena; Apoproteins; Bacterial Proteins; Cloning, Molecular; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genes, Bacterial; Histidine; Lyases; Mutation; Phycobilins; Phycocyanin; Phytochrome; Plasmids; Protein Subunits; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tetrapyrroles | 2006 |
CpSufE activates the cysteine desulfurase CpNifS for chloroplastic Fe-S cluster formation.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arabidopsis; Arabidopsis Proteins; Base Sequence; Carbon-Sulfur Lyases; Chloroplasts; Chromatography, Gel; Conserved Sequence; Cysteine; Enzyme Activation; Green Fluorescent Proteins; Histidine; Immunoblotting; Iron; Iron-Sulfur Proteins; Microscopy, Confocal; Molecular Sequence Data; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Subcellular Fractions; Sulfur | 2006 |
Infrared spectra and molar absorption coefficients of the 20 alpha amino acids in aqueous solutions in the spectral range from 1800 to 500 cm(-1).
Topics: Absorption; Amino Acids; Carbon; Cysteine; Histidine; Hydrogen-Ion Concentration; Methionine; Protons; Spectrophotometry; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Sulfur; Water | 2006 |
Preparation, crystallization and X-ray diffraction analysis to 1.5 A resolution of rat cysteine dioxygenase, a mononuclear iron enzyme responsible for cysteine thiol oxidation.
Topics: Animals; Binding Sites; Catalysis; Cloning, Molecular; Crystallization; Cysteine; Cysteine Dioxygenase; Dioxygenases; DNA, Complementary; Factor Xa; Histidine; Iron; Liver; Oxidation-Reduction; Oxygen; Rats; Recombinant Fusion Proteins; Recombinant Proteins; Solubility; Sulfhydryl Compounds; Temperature; X-Ray Diffraction | 2005 |
Structures of thiolate- and carboxylate-ligated ferric H93G myoglobin: models for cytochrome P450 and for oxyanion-bound heme proteins.
Topics: Binding Sites; Carboxylic Acids; Circular Dichroism; Crystallography, X-Ray; Cysteine; Cytochrome P-450 Enzyme System; Ferric Compounds; Hemeproteins; Histidine; Ligands; Mercaptoethanol; Models, Biological; Models, Molecular; Mutation; Myoglobin | 2006 |
The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary hemochromatosis.
Topics: Adult; Aged; Aspartic Acid; Cysteine; Fatty Liver; Female; Genetic Predisposition to Disease; Glucose Intolerance; Hemochromatosis; Hepatitis; Heterozygote; Histidine; Homozygote; Humans; Iron Overload; Liver Cirrhosis; Male; Metabolic Syndrome; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prospective Studies; Risk Factors; Tyrosine | 2006 |
The cysteine-histidine-rich region of the movement protein of Cucumber mosaic virus contributes to plasmodesmal targeting, zinc binding and pathogenesis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Artificial Gene Fusion; Cucumovirus; Cysteine; DNA Mutational Analysis; Genes, Reporter; Green Fluorescent Proteins; Histidine; Microscopy, Fluorescence; Molecular Sequence Data; Mutagenesis; Mutation, Missense; Plant Viral Movement Proteins; Plasmodesmata; Protein Structure, Tertiary; Recombinant Fusion Proteins; Viral Proteins; Virulence; Zinc | 2006 |
Fluorophore-assisted light inactivation of calmodulin involves singlet-oxygen mediated cross-linking and methionine oxidation.
Topics: Amino Acid Sequence; Animals; Calmodulin; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cysteine; Fluoresceins; Fluorescent Dyes; Histidine; Kinetics; Light; Mass Spectrometry; Methionine; Mice; Molecular Sequence Data; Myosin-Light-Chain Kinase; Organometallic Compounds; Oxidation-Reduction; Peptide Fragments; Peptides; Protein Structure, Tertiary; Rabbits; Reactive Oxygen Species; Ryanodine Receptor Calcium Release Channel; Singlet Oxygen; Trypsin | 2006 |
Hydrogen bonding affects the [NiFe] active site of Desulfovibrio vulgaris Miyazaki F hydrogenase: a hyperfine sublevel correlation spectroscopy and density functional theory study.
Topics: Chemical Phenomena; Chemistry, Physical; Cysteine; Desulfovibrio vulgaris; Electron Spin Resonance Spectroscopy; Histidine; Hydrogen Bonding; Hydrogenase; Models, Molecular | 2006 |
Structure of a Leu3-DNA complex: recognition of everted CGG half-sites by a Zn2Cys6 binuclear cluster protein.
Topics: Amino Acid Motifs; Amino Acid Sequence; Base Sequence; Binding Sites; Crystallography, X-Ray; Cysteine; Dimerization; DNA; DNA-Binding Proteins; DNA, Fungal; Fungal Proteins; Histidine; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Trans-Activators; Transcription Factors; Transcription, Genetic; Zinc | 2006 |
Redox sensing and histidine oxidation: no longer PerR-fect strangers.
Topics: Bacillus subtilis; Bacterial Proteins; Binding Sites; Catalysis; Cations, Divalent; Cysteine; DNA; Histidine; Hydrogen Peroxide; Iron; Models, Chemical; Oxidants; Oxidation-Reduction; Oxidative Stress; Repressor Proteins; Transcription Factors | 2006 |
Mutagenic definition of a papain-like catalytic triad, sufficiency of the N-terminal domain for single-site core catalytic enzyme acylation, and C-terminal domain for augmentative metal activation of a eukaryotic phytochelatin synthase.
Topics: Acylation; Amino Acid Sequence; Aminoacyltransferases; Arabidopsis; Aspartic Acid; Binding Sites; Cadmium; Catalysis; Cysteine; Enzyme Activation; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Papain; Protein Structure, Tertiary; Sequence Homology, Amino Acid | 2006 |
High-molecular-weight protein (pUL48) of human cytomegalovirus is a competent deubiquitinating protease: mutant viruses altered in its active-site cysteine or histidine are viable.
Topics: Binding Sites; Cells, Cultured; Cysteine; Cysteine Endopeptidases; Cytomegalovirus; Fibroblasts; Histidine; Humans; Mutation, Missense; Viral Proteins; Virion; Virus Replication | 2006 |
Synthetic protein-protein interaction domains created by shuffling Cys2His2 zinc-fingers.
Topics: Binding Sites; Cysteine; DNA-Binding Proteins; Genes, Reporter; Histidine; Protein Binding; Protein Engineering; Zinc Fingers | 2006 |
A combinatorial approach to minimal peptide models of a metalloprotein active site.
Topics: Amino Acid Sequence; Binding Sites; Combinatorial Chemistry Techniques; Cysteine; Histidine; Hydrolysis; Ligands; Metalloproteins; Molecular Sequence Data; Molecular Structure; Nitrophenols; Peptide Library; Peptides; Sequence Analysis, Protein; Time Factors; Zinc | 2006 |
Nickel superoxide dismutase reaction mechanism studied by hybrid density functional methods.
Topics: Algorithms; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Free Radicals; Histidine; Hydrogen Peroxide; Kinetics; Mutation; Nickel; Nitrogen; Oxidation-Reduction; Oxygen; Protein Conformation; Superoxide Dismutase | 2006 |
Apolipoprotein A-I-mimetic peptides with antioxidant actions.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antioxidants; Apolipoprotein A-I; Aryldialkylphosphatase; Biomimetics; Copper; Cysteine; Histidine; Hypochlorous Acid; Kinetics; Linoleic Acids; Lipid Peroxides; Lipoproteins, LDL; Liposomes; Molecular Sequence Data; Oxidation-Reduction; Peptides; Phosphatidylserines; Solubility | 2006 |
Assignment of the zinc ligands in RsrA, a redox-sensing ZAS protein from Streptomyces coelicolor.
Topics: Amino Acid Motifs; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Conserved Sequence; Cysteine; Histidine; Ligands; Molecular Sequence Data; Oxidation-Reduction; Transcription Factors; Zinc | 2006 |
The cell lysis activity of the Streptococcus agalactiae bacteriophage B30 endolysin relies on the cysteine, histidine-dependent amidohydrolase/peptidase domain.
Topics: Amidohydrolases; Amino Acid Sequence; Animals; Cattle; Cysteine; Endopeptidases; Histidine; Lysogeny; Mastitis, Bovine; Peptide Hydrolases; Streptococcus agalactiae; Streptococcus Phages | 2006 |
Site-specific immobilization of genetically engineered variants of Candida antarctica lipase B.
Topics: Amino Acid Substitution; Butyrates; Catalysis; Cysteine; Enzymes, Immobilized; Escherichia coli; Fungal Proteins; Glass; Histidine; Lipase; Maleimides; Oligopeptides; Peptides; Polyethylene Glycols; Protein Engineering; Recombinant Fusion Proteins; Succinimides | 2006 |
Roles of the heme and heme ligands in the activation of CooA, the CO-sensing transcriptional activator.
Topics: Amino Acid Sequence; Bacterial Proteins; Cysteine; Heme; Hemeproteins; Histidine; Ligands; Trans-Activators | 2006 |
Drosophila nuclear receptor E75 is a thiolate hemoprotein.
Topics: Alanine; Amino Acid Sequence; Animals; Cysteine; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Electron Spin Resonance Spectroscopy; Gene Expression; Heme; Hemeproteins; Histidine; Humans; Ligands; Molecular Sequence Data; Mutation; Protein Binding; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; Sequence Alignment; Solubility; Spectrophotometry, Ultraviolet; Sulfur; Transcription Factors | 2006 |
The unorthodox SNAP50 zinc finger domain contributes to cooperative promoter recognition by human SNAPC.
Topics: Amino Acid Sequence; Cysteine; DNA-Binding Proteins; HeLa Cells; Histidine; Humans; Molecular Sequence Data; Promoter Regions, Genetic; Protein Structure, Tertiary; RNA; Sequence Homology, Amino Acid; Transcription Factors; Zinc Fingers | 2006 |
Identifying cysteines and histidines in transition-metal-binding sites using support vector machines and neural networks.
Topics: Amino Acid Sequence; Binding Sites; Computational Biology; Cysteine; Histidine; Metalloproteins; Metals, Heavy; Molecular Sequence Data; Neural Networks, Computer | 2006 |
A novel regulatory metal binding domain is present in the C terminus of Arabidopsis Zn2+-ATPase HMA2.
Topics: Absorptiometry, Photon; Adenosine Triphosphatases; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Carrier Proteins; Cell Membrane; Circular Dichroism; Cysteine; Enzyme Stability; Histidine; Kinetics; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Sulfhydryl Compounds; Zinc | 2006 |
Zinc finger protein 1 (ThZF1) from salt cress (Thellungiella halophila) is a Cys-2/His-2-type transcription factor involved in drought and salt stress.
Topics: Amino Acid Sequence; Arabidopsis; Base Sequence; Blotting, Northern; Brassicaceae; Cell Nucleus; Cysteine; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Plant; Genetic Complementation Test; Green Fluorescent Proteins; Histidine; Molecular Sequence Data; Mutation; Plant Proteins; Plants, Genetically Modified; Polyethylene Glycols; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sodium Chloride; Transcription Factors; Zinc Fingers | 2007 |
Angle-dependent terahertz time-domain spectroscopy of amino acid single crystals.
Topics: Amino Acids; Crystallization; Cysteine; Histidine; Hydrogen Bonding; Spectrum Analysis; Spectrum Analysis, Raman; Temperature | 2006 |
Heme-heme interactions in the cytochrome b6f complex: EPR spectroscopy and correlation with structure.
Topics: Cysteine; Cytochrome b6f Complex; Electron Spin Resonance Spectroscopy; Heme; Histidine; Molecular Structure | 2006 |
Entamoeba histolytica: an ecto-phosphatase activity regulated by oxidation-reduction reactions.
Topics: Animals; Chlorides; Cysteine; Dithiothreitol; Entamoeba histolytica; Glutathione; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Molybdenum; Nitrophenols; Organophosphorus Compounds; Oxidation-Reduction; Phosphoric Monoester Hydrolases; Sodium Fluoride; Virulence; Zinc Compounds | 2007 |
Histidine ligands in bacterial metallothionein enhance cluster stability.
Topics: Amino Acid Sequence; Bacterial Proteins; Cadmium; Cysteine; Histidine; Ligands; Metallothionein; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Folding; Sequence Homology, Amino Acid; Static Electricity; Zinc | 2007 |
Engineering copper sites in proteins: loops confer native structures and properties to chimeric cupredoxins.
Topics: Azurin; Binding Sites; Copper; Cysteine; Electron Transport; Histidine; Immunotoxins; Ligands; Methionine; Plastocyanin; Protein Structure, Tertiary; Protons; Spectrophotometry, Ultraviolet | 2007 |
Conformational stabilization at the active site of molluskan (Rapana thomasiana) hemocyanin by a cysteine-histidine thioether bridge A study by mass spectrometry and molecular modeling.
Topics: Amino Acid Sequence; Animals; Binding Sites; Computer Simulation; Cysteine; Hemocyanins; Histidine; Models, Molecular; Molecular Sequence Data; Mollusca; Primulaceae; Sequence Alignment; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2007 |
The EAR-motif of the Cys2/His2-type zinc finger protein Zat7 plays a key role in the defense response of Arabidopsis to salinity stress.
Topics: Amino Acid Motifs; Arabidopsis; Arabidopsis Proteins; Carrier Proteins; Cysteine; Histidine; Models, Biological; Models, Genetic; Phenotype; Plants, Genetically Modified; Protein Structure, Tertiary; RNA Interference; Salts; Two-Hybrid System Techniques; Zinc Fingers | 2007 |
The carboxylate shift in zinc enzymes: a computational study.
Topics: Aspartic Acid; Carboxylic Acids; Catalytic Domain; Computational Biology; Crystallography, X-Ray; Cysteine; Electron Transport; Enzymes; Glutamic Acid; Histidine; Ligands; Metalloproteins; Oxygen; Protein Conformation; Zinc | 2007 |
FOXL2 mutations in Chinese patients with blepharophimosis-ptosis-epicanthus inversus syndrome.
Topics: Asian People; Blepharophimosis; Blepharoptosis; Cysteine; Cytosine; Eye Abnormalities; Eyelids; Forkhead Box Protein L2; Forkhead Transcription Factors; Guanine; Heterozygote; Histidine; Humans; Mutation; Mutation, Missense; Polymorphism, Single-Stranded Conformational; Serine; Syndrome; Thymine; Tyrosine | 2007 |
Identification of catalytic cysteine, histidine, and lysine residues in Escherichia coli homoserine transsuccinylase.
Topics: Catalysis; Cysteine; Escherichia coli; Histidine; Homoserine O-Succinyltransferase; Hydrogen-Ion Concentration; Iodoacetamide; Lysine; Models, Molecular; Mutagenesis, Site-Directed | 2007 |
Site-specific fluorescent labeling of poly-histidine sequences using a metal-chelating cysteine.
Topics: Binding Sites; Bridged Bicyclo Compounds; Chelating Agents; Cross-Linking Reagents; Cysteine; Fluorescent Dyes; Histidine; Nitrilotriacetic Acid; Oligopeptides; Organometallic Compounds; Spectrometry, Fluorescence; Staining and Labeling; Substrate Specificity | 2007 |
Identification of essential histidine and cysteine residues of the H+/organic cation antiporter multidrug and toxin extrusion (MATE).
Topics: 4-Chloromercuribenzenesulfonate; Animals; Antiporters; Biological Transport; Cysteine; Diethyl Pyrocarbonate; Gene Expression; Histidine; Humans; Mutagenesis, Site-Directed; Organic Cation Transport Proteins; Rats; Tetraethylammonium; Toxins, Biological | 2007 |
Effect of surface histidine mutations and their number on the partitioning and refolding of recombinant human granulocyte-colony stimulating factor (Cys17Ser) in aqueous two-phase systems containing chelated metal ions.
Topics: Animals; Cell Line, Tumor; Chelating Agents; Cysteine; Electrophoresis, Polyacrylamide Gel; Granulocyte Colony-Stimulating Factor; Histidine; Metals; Mice; Mutation; Protein Folding; Recombinant Proteins; Serine; Water | 2007 |
A zinc-finger like metal binding site in the nucleosome.
Topics: Animals; Binding Sites; Chickens; Cobalt; Cysteine; Histidine; Histones; Models, Molecular; Nucleosomes; Protein Conformation; Spectrophotometry, Ultraviolet; Zinc; Zinc Fingers | 2007 |
Cell-specific and nuclear targeting with [M(CO)(3)](+) (M=(99m)Tc, Re)-based complexes conjugated to acridine orange and bombesin.
Topics: Acridine Orange; Bombesin; Cell Nucleus; Crystallography, X-Ray; Cysteine; Histidine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Rhenium; Spectrometry, Mass, Electrospray Ionization | 2007 |
Enantioselective crystallization of histidine on chiral self-assembled films of cysteine.
Topics: Crystallization; Cysteine; Histidine; Membranes, Artificial; Stereoisomerism | 2007 |
Multiple fungal enzymes possess cysteine synthase activity in vitro.
Topics: Arginine; Aspergillus nidulans; Blotting, Northern; Carbon-Oxygen Lyases; Catalysis; Cysteine; Cysteine Synthase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Histidine; Models, Biological; Mutation; Phylogeny; Proline; Serine; Sulfates | 2007 |
Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Cysteine; Disulfides; Dual-Specificity Phosphatases; Fungi; Histidine; Humans; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Oxidative Stress; Phosphoprotein Phosphatases; Phosphotyrosine; Protein Tyrosine Phosphatases; Saccharomyces cerevisiae Proteins; Substrate Specificity | 2007 |
Perlinhibin, a cysteine-, histidine-, and arginine-rich miniprotein from abalone (Haliotis laevigata) nacre, inhibits in vitro calcium carbonate crystallization.
Topics: Amino Acid Sequence; Animals; Arginine; Calcium Carbonate; Crystallization; Crystallography, X-Ray; Cysteine; Histidine; Microscopy, Atomic Force; Molecular Sequence Data; Proteins; Snails; Solutions; Spectrometry, Mass, Electrospray Ionization | 2007 |
The unusually strong hydrogen bond between the carbonyl of Q(A) and His M219 in the Rhodobacter sphaeroides reaction center is not essential for efficient electron transfer from Q(A)(-) to Q(B).
Topics: Binding Sites; Cysteine; Electron Transport; Histidine; Hydrogen Bonding; Iron; Kinetics; Light; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Oxidation-Reduction; Photosynthetic Reaction Center Complex Proteins; Protein Conformation; Quinones; Rhodobacter sphaeroides; Spectroscopy, Fourier Transform Infrared; Water | 2007 |
Protein arginine deiminase 4: evidence for a reverse protonation mechanism.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Citrulline; Cysteine; Histidine; Humans; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Protons; Recombinant Proteins; Substrate Specificity | 2007 |
The TatA subunit of Escherichia coli twin-arginine translocase has an N-in topology.
Topics: Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cysteine; Cytoplasm; Dimerization; Escherichia coli; Escherichia coli Proteins; Histidine; Membrane Potentials; Membrane Transport Proteins; Models, Molecular; Point Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Uncoupling Agents | 2007 |
Analysis of modified apolipoprotein B-100 structures formed in oxidized low-density lipoprotein using LC-MS/MS.
Topics: Acrolein; Aldehydes; Amino Acid Sequence; Apolipoprotein B-100; Chloroform; Chromatography, Liquid; Copper Sulfate; Cysteine; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Kynurenine; Lipoproteins, LDL; Lysine; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Polyvinyls; Tandem Mass Spectrometry; Trypsin; Tryptophan | 2007 |
Biogenesis of the essential Tim9-Tim10 chaperone complex of mitochondria: site-specific recognition of cysteine residues by the intermembrane space receptor Mia40.
Topics: Cysteine; Cystine; Disulfides; Escherichia coli; Gene Expression Regulation, Fungal; Histidine; Membrane Proteins; Membrane Transport Proteins; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Precursor Protein Import Complex Proteins; Mitochondrial Proteins; Models, Genetic; Oxidoreductases Acting on Sulfur Group Donors; Protein Binding; Protein Transport; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2007 |
Toward a property/function relationship for metallothioneins: histidine coordination and unusual cluster composition in a zinc-metallothionein from plants.
Topics: Amino Acid Sequence; Cysteine; Databases, Protein; Deuterium; Histidine; Metallothionein; Plant Proteins; Sequence Alignment; Sequence Homology, Amino Acid | 2007 |
The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster.
Topics: Binding Sites; Cysteine; Histidine; Humans; Hydrogen-Ion Concentration; Iron-Binding Proteins; Iron-Sulfur Proteins; Membrane Proteins; Mitochondrial Membranes; Mitochondrial Proteins; Oxidation-Reduction; Spectrum Analysis; Zinc Fingers | 2007 |
Expression, purification and functional analysis of hexahistidine-tagged human glutathione S-transferase P1-1 and its cysteinyl mutants.
Topics: Base Sequence; Catalysis; Circular Dichroism; Cysteine; DNA Primers; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Fluorescence; Glutathione Transferase; Histidine; Humans; Kinetics; Mutagenesis, Site-Directed; Oligopeptides; Oxidation-Reduction; Recombinant Proteins | 2007 |
Copper sensing based on the far-red fluorescent protein, HcRed, from Heteractis crispa.
Topics: Animals; Biosensing Techniques; Cations, Divalent; Circular Dichroism; Copper; Cysteine; Diethyl Pyrocarbonate; Histidine; Iodoacetamide; Luminescent Proteins; Sea Anemones; Sensitivity and Specificity; Spectrometry, Fluorescence | 2007 |
Computational analysis of the R85C and R85H epilepsy mutations in Na+ channel beta1 subunits.
Topics: Arginine; Cell Line, Transformed; Computer Simulation; Cysteine; Electric Stimulation; Histidine; Humans; Ion Channel Gating; Membrane Potentials; Models, Neurological; Mutation; Patch-Clamp Techniques; Sodium Channels; Transfection; Voltage-Gated Sodium Channel beta-1 Subunit | 2007 |
The PICM chemical scanning method for identifying domain-domain and protein-protein interfaces: applications to the core signaling complex of E. coli chemotaxis.
Topics: Binding Sites; Biochemistry; Chemotaxis; Cysteine; Escherichia coli; Histidine; Models, Molecular; Oligonucleotide Probes; Plasmids; Protein Conformation; Protein Engineering; Protein Interaction Mapping; Protein Structure, Tertiary; Proteins; Salmonella typhimurium; Signal Transduction | 2007 |
Stimulation and oxidative catalytic inactivation of thermolysin by copper.Cys-Gly-His-Lys.
Topics: Amino Acid Motifs; Amino Acid Sequence; Catalysis; Copper; Cysteine; Electrochemistry; Enzyme Activation; Glycine; Histidine; Lysine; Macromolecular Substances; Molecular Sequence Data; Molecular Structure; Oligopeptides; Organometallic Compounds; Oxidation-Reduction; Sequence Alignment; Thermolysin | 2007 |
Participation of Cys123alpha of Escherichia coli succinyl-CoA synthetase in catalysis.
Topics: Catalysis; Crystallography, X-Ray; Cysteine; Escherichia coli; Histidine; Kinetics; Models, Molecular; Mutation; Protein Structure, Tertiary; Protein Subunits; Succinate-CoA Ligases; Temperature | 2007 |
Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses.
Topics: Aging; Animals; Binding, Competitive; Cattle; Crystallins; Cysteine; Glutathione; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Ketones; Kynurenine; Lens, Crystalline; Protein Processing, Post-Translational; Ultraviolet Rays | 2007 |
Post-translational modifications in the active site region of methyl-coenzyme M reductase from methanogenic and methanotrophic archaea.
Topics: Amino Acid Sequence; Archaea; Arginine; Binding Sites; Cysteine; Glutamine; Glycine; Histidine; Methane; Molecular Sequence Data; Oxidoreductases; Protein Processing, Post-Translational; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin | 2007 |
Identification and biochemical characterization of unique secretory nucleases of the human enteric pathogen, Entamoeba histolytica.
Topics: Amino Acid Sequence; Animals; Catalysis; Cell-Free System; Cysteine; Disulfides; Entamoeba histolytica; Epitopes; Genes, Protozoan; Histidine; Humans; Hydrolysis; Molecular Sequence Data; Open Reading Frames; Plasmids; Precipitin Tests; Protein Sorting Signals; Protein Structure, Tertiary; Ribonucleases | 2007 |
Crystal structure of human mitoNEET reveals distinct groups of iron sulfur proteins.
Topics: Amino Acid Motifs; Amino Acid Sequence; Consensus Sequence; Conserved Sequence; Crystallography, X-Ray; Cysteine; Histidine; Humans; Hydrophobic and Hydrophilic Interactions; Iron-Binding Proteins; Iron-Sulfur Proteins; Ligands; Membrane Proteins; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Solubility | 2007 |
The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain.
Topics: Amino Acid Sequence; Baculoviridae; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cysteine; Disulfides; Furin; Histidine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Oligopeptides; Proprotein Convertase 9; Proprotein Convertases; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Resistin; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Serine Endopeptidases; Static Electricity | 2007 |
Synthesis and characterization of styrene oxide adducts with cysteine, histidine, and lysine in human globin.
Topics: Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Environmental Monitoring; Environmental Pollutants; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Globins; Histidine; Humans; Lysine; Magnetic Resonance Spectroscopy; Stereoisomerism | 2007 |
The cys-loop ligand-gated ion channel gene superfamily of the red flour beetle, Tribolium castaneum.
Topics: Amino Acid Sequence; Animals; Cysteine; Glutamic Acid; Histidine; Ion Channel Gating; Ion Channels; Molecular Sequence Data; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Tribolium | 2007 |
All-electron calculations of the nucleation structures in metal-induced zinc-finger folding: role of the Peptide backbone.
Topics: Cysteine; Electrons; Histidine; Ligands; Models, Molecular; Molecular Structure; Nitrogen; Oxygen; Peptides; Protein Binding; Protein Folding; Sulfur; Thermodynamics; Water; Zinc; Zinc Fingers | 2007 |
Deducing the energetic cost of protein folding in zinc finger proteins using designed metallopeptides.
Topics: Amino Acid Motifs; Calorimetry; Cysteine; Histidine; Hydrogen-Ion Concentration; Kinetics; Ligands; Models, Chemical; Models, Molecular; Molecular Conformation; Peptides; Protein Folding; Spectrometry, Fluorescence; Thermodynamics; Zinc; Zinc Fingers | 2007 |
Replacement of histidine in position 105 in the α₅ subunit by cysteine stimulates zolpidem sensitivity of α₅β₂γ₂ GABA(A) receptors.
Topics: Amino Acid Substitution; Animals; Cysteine; Dose-Response Relationship, Drug; Electrophysiological Phenomena; Excitatory Amino Acid Agonists; GABA Agonists; gamma-Aminobutyric Acid; Histidine; Humans; Hydrogen-Ion Concentration; Oocytes; Patch-Clamp Techniques; Pyridines; Receptors, GABA-A; Structure-Activity Relationship; Xenopus; Zolpidem | 2007 |
The prokaryotic Cys2His2 zinc-finger adopts a novel fold as revealed by the NMR structure of Agrobacterium tumefaciens Ros DNA-binding domain.
Topics: Agrobacterium tumefaciens; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Cysteine; DNA; DNA-Binding Proteins; Histidine; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Folding; Protein Structure, Tertiary; Repressor Proteins; Sequence Alignment; Zinc Fingers | 2007 |
Novel single-chain Fv' formats for the generation of immunoliposomes by site-directed coupling.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chromatography, Gel; Cysteine; Histidine; Hot Temperature; Humans; Immunoconjugates; Immunoglobulin Variable Region; Liposomes; Mice; Micelles; Oligopeptides; Serine Endopeptidases | 2008 |
EXAFS reveals a structural zinc binding site in the bovine NADH-Q oxidoreductase.
Topics: Animals; Binding Sites; Cattle; Cysteine; Histidine; Models, Molecular; Quinone Reductases; Spectrophotometry; Spectrum Analysis; Structure-Activity Relationship; X-Rays; Zinc | 2007 |
The three-dimensional structure of VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form.
Topics: Amino Acid Sequence; Asparagine; Bacterial Proteins; beta-Lactamases; Binding Sites; Conserved Sequence; Cysteine; Escherichia coli; Histidine; Hydrophobic and Hydrophilic Interactions; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Weight; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Pseudomonas aeruginosa; Sequence Homology, Amino Acid; Substrate Specificity; Zinc | 2008 |
Is dihydrolipoic acid among the reductive activators of parasite CysHis proteases?
Topics: Animals; Antioxidants; Cathepsin B; Cysteine; Cysteine Endopeptidases; Dithiothreitol; Enzyme Activation; Enzyme Reactivators; Glutathione; Histidine; Iron; Mammals; Oxidation-Reduction; Plasmodium falciparum; Protozoan Proteins; Thioctic Acid; Trypanosoma cruzi | 2008 |
Evaluation of maleimide derivative of DOTA for site-specific labeling of recombinant affibody molecules.
Topics: Animals; Binding Sites; Chelating Agents; Cysteine; Heterocyclic Compounds, 1-Ring; Histidine; Indium Radioisotopes; Maleimides; Mice; Mice, Inbred BALB C; Neoplasms; Peptides; Radionuclide Imaging; Receptor, ErbB-2; Recombinant Fusion Proteins; Sensitivity and Specificity; Transplantation, Heterologous | 2008 |
Metal-coupled folding of Cys2His2 zinc-finger.
Topics: Animals; Cysteine; Histidine; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Protein Folding; Protein Structure, Secondary; Zinc; Zinc Fingers | 2008 |
Pyridine-tert-nitrogen-phenol ligands: N,N,O-Type tripodal chelates for the [M(CO)3]+ core (M = Re, Tc).
Topics: Binding Sites; Chelating Agents; Crystallography, X-Ray; Cysteine; Dimerization; Histidine; Isotope Labeling; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Nitrogen; Organometallic Compounds; Oxygen; Phenol; Pyridines; Radiopharmaceuticals; Rhenium; Technetium; Time Factors | 2008 |
Generation of nucleophilic character in the Cys25/His159 ion pair of papain involves Trp177 but not Asp158.
Topics: Aspartic Acid; Cysteine; Histidine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Papain; Spectrometry, Mass, Electrospray Ionization; Static Electricity; Tryptophan | 2008 |
Steady-state and pre-steady-state kinetic evaluation of severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro cysteine protease: development of an ion-pair model for catalysis.
Topics: Acrylates; Alkylation; Catalysis; Coronavirus 3C Proteases; Cysteine; Cysteine Endopeptidases; Dipeptides; Enzyme Activation; Enzyme Inhibitors; Enzyme Stability; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Ions; Kinetics; Models, Biological; Severe acute respiratory syndrome-related coronavirus; Solvents; Static Electricity; Transferases; Viral Proteins | 2008 |
A conserved poxvirus NlpC/P60 superfamily protein contributes to vaccinia virus virulence in mice but not to replication in cell culture.
Topics: Amino Acid Sequence; Animals; Cell Line; Chick Embryo; Conserved Sequence; Cysteine; Fibroblasts; Histidine; Humans; Keratinocytes; Mice; Molecular Sequence Data; Papain; Peptide Hydrolases; Protein Folding; Vaccinia virus; Viral Proteins; Virion; Virulence; Virus Replication | 2008 |
An endosomolytic Tat peptide produced by incorporation of histidine and cysteine residues as a nonviral vector for DNA transfection.
Topics: Animals; Cell Line, Tumor; Cell Survival; Central Nervous System; Cysteine; DNA; DNA, Circular; Endosomes; Gene Expression; Gene Transfer Techniques; Genetic Vectors; Histidine; Humans; Luciferases; Macrolides; Male; Microscopy, Atomic Force; Oxidation-Reduction; Particle Size; Peptide Fragments; Rats; Rats, Wistar; Static Electricity; tat Gene Products, Human Immunodeficiency Virus; Transfection | 2008 |
A peptide dendrimer model for vitamin B12 transport proteins.
Topics: Combinatorial Chemistry Techniques; Cysteine; Dendrimers; Histidine; Ligands; Models, Molecular; Molecular Conformation; Peptide Library; Peptides; Transcobalamins; Vitamin B 12 | 2008 |
HFE gene mutations in a population of Italian Parkinson's disease patients.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Cysteine; DNA Mutational Analysis; Female; Gene Frequency; Genotype; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Italy; Male; Membrane Proteins; Middle Aged; Mutation; Parkinson Disease; Serine | 2008 |
The Q-type C2H2 zinc finger subfamily of transcription factors in Triticum aestivum is predominantly expressed in roots and enriched with members containing an EAR repressor motif and responsive to drought stress.
Topics: Abscisic Acid; Amino Acid Sequence; Conserved Sequence; Cysteine; Disasters; Histidine; Molecular Sequence Data; Phylogeny; Plant Proteins; RNA, Messenger; RNA, Plant; Seeds; Transcription Factors; Triticum; Zinc Fingers | 2008 |
Mechanism of copper induced fluorescence quenching of red fluorescent protein, DsRed.
Topics: Animals; Circular Dichroism; Copper; Cysteine; Fluorescence; Histidine; Luminescent Proteins; Mutation; Protein Binding; Protein Structure, Secondary; Spectrophotometry, Ultraviolet | 2008 |
Zn2+ binding to human calbindin D(28k) and the role of histidine residues.
Topics: 5'-Nucleotidase; Acetates; Allosteric Regulation; Amino Acid Sequence; Calbindins; Calcium; Calorimetry; Circular Dichroism; Cysteine; Escherichia coli; Histidine; Humans; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Recombinant Proteins; S100 Calcium Binding Protein G; Xanthenes; Zinc | 2008 |
The M1P1 loop of TASK3 K2P channels apposes the selectivity filter and influences channel function.
Topics: Cysteine; Electrophysiology; Gene Expression Regulation; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Mutation; Patch-Clamp Techniques; Point Mutation; Potassium Channels, Tandem Pore Domain; Protein Structure, Tertiary; Zinc | 2008 |
The importance of the long type 1 copper-binding loop of nitrite reductase for structure and function.
Topics: Azurin; Binding Sites; Catalysis; Copper; Cysteine; Electron Spin Resonance Spectroscopy; Histidine; Methionine; Molecular Structure; Mutagenesis, Site-Directed; Nitrite Reductases; Spectrophotometry, Ultraviolet; Zinc | 2008 |
Interaction between bisphenol derivatives and protein disulphide isomerase (PDI) and inhibition of PDI functions: requirement of chemical structure for binding to PDI.
Topics: Animals; Benzhydryl Compounds; Binding Sites; Binding, Competitive; Cysteine; Histidine; Models, Biological; Models, Chemical; Molecular Chaperones; Oxygen; Phenols; Protein Binding; Protein Disulfide-Isomerases; Protein Folding; Rats; Recombinant Fusion Proteins | 2008 |
Prebiotic origin of glycolytic metabolism: histidine and cysteine can produce acetyl CoA from glucose via reactions homologous to non-phosphorylated Entner-Doudoroff pathway.
Topics: Acetyl Coenzyme A; Amino Acids; Biochemistry; Catalysis; Chromatography, Thin Layer; Cysteine; Gluconates; Glucose; Glycolysis; Histidine; Mass Spectrometry; Models, Biological; NAD; Phosphorylation; Time Factors | 2008 |
Two isomorphous ZnII/CoII complexes with tri-tert-butoxysilanethiol and histamine, and (4-hydroxymethyl-1H-imidazole-kappaN)bis(tri-tert-butoxysilanethiolato-kappa2O,S)zinc(II).
Topics: Cobalt; Crystallography; Cysteine; Histamine; Histidine; Hydrogen Bonding; Molecular Structure; Organometallic Compounds; Proteins; Zinc | 2008 |
A rotor-stator cross-link in the F1-ATPase blocks the rate-limiting step of rotational catalysis.
Topics: Adenosine Triphosphate; Catalysis; Cross-Linking Reagents; Cysteine; Electrochemistry; Escherichia coli; Histidine; Hydrolysis; Kinetics; Models, Biological; Molecular Conformation; Mutation; NAD; Plasmids; Proton-Translocating ATPases | 2008 |
MetalDetector: a web server for predicting metal-binding sites and disulfide bridges in proteins from sequence.
Topics: Amino Acid Sequence; Binding Sites; Computational Biology; Computer Simulation; Cysteine; Databases, Protein; Disulfides; Histidine; Internet; Metalloproteins; Molecular Sequence Data; Sequence Alignment; Sequence Analysis, Protein | 2008 |
Control of the coordination structure of organometallic palladium complexes in an apo-ferritin cage.
Topics: Apoferritins; Binding Sites; Crystallography, X-Ray; Cysteine; Glutamic Acid; Histidine; Mutation; Organometallic Compounds; Palladium | 2008 |
The transcription regulator RcoM-2 from Burkholderia xenovorans is a cysteine-ligated hemoprotein that undergoes a redox-mediated ligand switch.
Topics: Bacterial Proteins; Burkholderia; Carbon Monoxide; Cysteine; DNA-Binding Proteins; Electron Spin Resonance Spectroscopy; Hemeproteins; Histidine; Iron; Molecular Structure; Nitric Oxide; Oxidation-Reduction; Protein Binding; Spectrum Analysis, Raman; Trans-Activators | 2008 |
Solution NMR structure of the NlpC/P60 domain of lipoprotein Spr from Escherichia coli: structural evidence for a novel cysteine peptidase catalytic triad.
Topics: Amino Acid Sequence; Catalysis; Catalytic Domain; Cysteine; Cysteine Endopeptidases; Escherichia coli; Escherichia coli Proteins; Histidine; Hydrolases; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Peptide Hydrolases; Protein Folding; Protein Structure, Tertiary; Solutions | 2008 |
A structural study of cadmium interaction with aquatic microorganisms.
Topics: Adsorption; Biofilms; Cadmium; Cyanobacteria; Cysteine; Diatoms; Fresh Water; Histidine; Nitrates; Nitrogen; Oxygen; Plankton; Rhodopseudomonas; Seawater; Sodium Chloride; Soil Pollutants; Spectrometry, X-Ray Emission; Sulfhydryl Compounds | 2008 |
Photoactivity of kynurenine-derived UV filters.
Topics: Anaerobiosis; Cysteine; Glutathione; Histidine; Kynurenine; Photolysis; Quantum Theory; Scattering, Radiation; Time Factors; Ultraviolet Rays | 2008 |
Structure of the two transmembrane Cu+ transport sites of the Cu+ -ATPases.
Topics: Adenosine Triphosphatases; Archaeoglobus fulgidus; Binding Sites; Biological Transport; Copper; Cysteine; Histidine; Kinetics; Models, Biological; Molecular Chaperones; Mutagenesis, Site-Directed; Nitrophenols; Organophosphorus Compounds; Protein Transport; Tyrosine; X-Rays | 2008 |
Characterization of the activity and folding of the glutathione transferase from Escherichia coli and the roles of residues Cys(10) and His(106).
Topics: Amino Acid Sequence; Circular Dichroism; Cysteine; Escherichia coli; Escherichia coli Proteins; Glutathione; Glutathione Transferase; Histidine; Molecular Sequence Data; Mutation; Protein Binding; Protein Folding; Protein Structure, Secondary; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2009 |
Binding of Ni2+ and Cu2+ ions to peptides with a Cys-His motif.
Topics: Amino Acid Sequence; Copper; Cysteine; Disulfides; Histidine; Ions; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Sequence Data; Nickel; Peptides; Protein Binding; Protons; Spectrophotometry | 2008 |
The effect of cysteine, histidine, and methionine on the production of polycythemia by cobalt.
Topics: Cobalt; Cysteine; Histidine; Methionine; Polycythemia | 1948 |
Replacement of the axial histidine heme ligand with cysteine in nitrophorin 1: spectroscopic and crystallographic characterization.
Topics: Circular Dichroism; Crystallography, X-Ray; Cysteine; Heme; Hemeproteins; Histidine; Ligands; Models, Molecular; Mutation; Protein Conformation; Protein Engineering; Salivary Proteins and Peptides; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman | 2009 |
Further studies on the effect of cystine and histidine on the production of cobalt polycythemia.
Topics: Cobalt; Cysteine; Cystine; Histidine; Humans; Polycythemia; Polycythemia Vera | 1948 |
Structural elucidation of the Cys-His-Glu-Asn proteolytic relay in the secreted CHAP domain enzyme from the human pathogen Staphylococcus saprophyticus.
Topics: Asparagine; Bacterial Proteins; Catalytic Domain; Cysteine; Endopeptidases; Glutamic Acid; Histidine; Magnetic Resonance Spectroscopy; Protein Structure, Tertiary; Staphylococcus | 2009 |
Predicting DNA recognition by Cys2His2 zinc finger proteins.
Topics: Amino Acid Sequence; Base Sequence; Computational Biology; Cysteine; Databases, Nucleic Acid; DNA; DNA-Binding Proteins; Early Growth Response Protein 1; Histidine; Models, Biological; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; Zinc Fingers | 2009 |
A study of quenching and enhancing effects of some amino acids on peroxyoxalate chemiluminescence of rhodamine 6G.
Topics: Cysteine; Fluorescent Dyes; Histidine; Hydrogen-Ion Concentration; Kinetics; Least-Squares Analysis; Luminescence; Luminescent Measurements; Methionine; Oxalates; Rhodamines; Spectrometry, Fluorescence; Time Factors | 2009 |
Proton environment of reduced Rieske iron-sulfur cluster probed by two-dimensional ESEEM spectroscopy.
Topics: Bacterial Proteins; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport Complex III; Histidine; Hydrogen Bonding; Isotopes; Ligands; Magnetics; Protons; Rhodobacter sphaeroides; Water | 2009 |
Zinc modulation of hemi-gap-junction channel currents in retinal horizontal cells.
Topics: Animals; Bass; Biophysics; Calcium; Cations, Divalent; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Electric Stimulation; Gap Junctions; Histidine; Ion Channel Gating; Ion Channels; Membrane Potentials; Neural Inhibition; Patch-Clamp Techniques; Retinal Horizontal Cells; Zinc | 2009 |
Why do cysteine dioxygenase enzymes contain a 3-His ligand motif rather than a 2His/1Asp motif like most nonheme dioxygenases?
Topics: Amino Acid Motifs; Aspartic Acid; Biocatalysis; Catalytic Domain; Cysteine; Cysteine Dioxygenase; Heme; Histidine; Humans; Ligands; Models, Chemical; Models, Molecular | 2009 |
Characterization and expression analysis under bending and other abiotic factors of PtaZFP2, a poplar gene encoding a Cys2/His2 zinc finger protein.
Topics: Adaptation, Physiological; Base Sequence; Cysteine; DNA, Complementary; Gene Expression; Gene Expression Regulation, Plant; Genes, Plant; Gravitropism; Histidine; Mechanical Phenomena; Mechanotransduction, Cellular; Molecular Sequence Data; Plant Stems; Populus; Promoter Regions, Genetic; RNA, Messenger; Salt Tolerance; Stress, Physiological; Transcription Factors; Trees; Zinc Fingers | 2009 |
DNA recognition by the DNA primase of bacteriophage T7: a structure-function study of the zinc-binding domain.
Topics: Amino Acid Substitution; Bacteriophage T7; Biocatalysis; Chlorides; Crystallography, X-Ray; Cysteine; DNA Primase; DNA, Viral; Enzyme Stability; Histidine; Ligands; Mutant Proteins; Oligoribonucleotides; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship; Templates, Genetic; X-Ray Absorption Spectroscopy; Zinc; Zinc Compounds | 2009 |
Protein modification by acrolein: formation and stability of cysteine adducts.
Topics: Acrolein; Amino Acid Sequence; Animals; Cattle; Cysteine; Histidine; Hydrogen-Ion Concentration; Insulin; Lysine; Peptides; Schiff Bases; Spectrometry, Mass, Electrospray Ionization | 2009 |
Influence of key residues on the heterologous extracellular production of fungal ribonuclease U2 in the yeast Pichia pastoris.
Topics: Blotting, Western; Cysteine; Electrophoresis, Polyacrylamide Gel; Endoribonucleases; Histidine; Models, Molecular; Pichia; Protein Folding; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Temperature; Ustilago | 2009 |
Influence of the selected antioxidants on the stability of the Celsior solution used for perfusion and organ preservation purposes.
Topics: Antioxidants; Ascorbic Acid; Cysteine; Disaccharides; Drug Stability; Electrolytes; Fumarates; Glutamates; Glutathione; Histidine; Mannitol; Organ Preservation Solutions; Perfusion; Temperature | 2009 |
Resonance Raman studies of the (His)(Cys)3 2Fe-2S cluster of MitoNEET: comparison to the (Cys)4 mutant and implications of the effects of pH on the labile metal center.
Topics: Amino Acid Substitution; Cysteine; Drug Delivery Systems; Histidine; Humans; Hydrogen-Ion Concentration; Hypoglycemic Agents; Iron-Sulfur Proteins; Mitochondrial Membranes; Mitochondrial Proteins; Protons; Spectrum Analysis, Raman | 2009 |
Molecular recognition of the palmitoylation substrate Vac8 by its palmitoyltransferase Pfa3.
Topics: Acetyltransferases; Acyltransferases; Amino Acid Sequence; Aspartic Acid; Cysteine; Histidine; Lipoylation; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; src Homology Domains; Vacuoles; Vesicular Transport Proteins | 2009 |
Selective colorimetric sensing of histidine in aqueous solutions using cysteine modified silver nanoparticles in the presence of Hg2+.
Topics: Chemistry Techniques, Analytical; Cysteine; Histidine; Mercury; Nanoparticles; Sensitivity and Specificity; Silver; Solutions | 2009 |
Revisiting histidine-dependent acid phosphatases: a distinct group of tyrosine phosphatases.
Topics: Acid Phosphatase; Animals; Catalytic Domain; Cysteine; Histidine; Humans; Models, Biological; Neurons; Phosphates; Phylogeny; Plants; Protein Conformation; Protein Tyrosine Phosphatases; Species Specificity | 2009 |
Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1).
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Crystallization; Cysteine; Data Collection; Dimerization; Disulfides; Egg Proteins; Escherichia coli; Female; Helminth Proteins; Histidine; Interleukin-4; Molecular Sequence Data; Mutation; Nuclear Localization Signals; Recombinant Fusion Proteins; Schistosoma mansoni; Statistics as Topic; Temperature; X-Ray Diffraction | 2009 |
A zinc site in the C-terminal domain of RAG1 is essential for DNA cleavage activity.
Topics: Binding Sites; Biocatalysis; Chromatography, Gel; Conserved Sequence; Cysteine; DNA Cleavage; Histidine; Homeodomain Proteins; Ions; Ligands; Mutagenesis; Mutation; Protein Binding; Protein Folding; Protein Structure, Tertiary; Recombination, Genetic; Zinc | 2009 |
Structural adaptability of zinc binding sites: different structures in partially, fully, and heavy-metal loaded states.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Cysteine; Glutamic Acid; Histidine; Metalloproteins; Molecular Sequence Data; Molecular Structure; Zinc; Zinc Fingers | 2009 |
Functional analysis of N-terminal residues of ty1 integrase.
Topics: Amino Acid Motifs; Binding Sites; Conserved Sequence; Cysteine; Histidine; Integrases; Mutation; Protein Multimerization; Retroelements; Retroviridae; Saccharomyces cerevisiae; Virus Integration; Zinc | 2009 |
Selective immobilization of peptides exclusively via N-terminus cysteines by water-driven reactions on surfaces.
Topics: Alkanes; Animals; Cell Adhesion; Cell Culture Techniques; Chemistry; Cysteine; Histidine; Hydrogen-Ion Concentration; Metals; Models, Chemical; Peptides; Protein Structure, Tertiary; Sulfhydryl Compounds; Surface Properties; Water | 2009 |
The structural effects of the Cys-S-S-Cys bridge exchange by the His-Cu(II)-His motif studied on natural peptides--a promising tool for natural compounds-based design.
Topics: Amino Acid Motifs; Arginine; Cations; Circular Dichroism; Copper; Cysteine; Disulfides; Electron Spin Resonance Spectroscopy; Histidine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Oxytocin; Potentiometry; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet; Vasopressins | 2009 |
Challenging a paradigm: theoretical calculations of the protonation state of the Cys25-His159 catalytic diad in free papain.
Topics: Catalytic Domain; Cysteine; Histidine; Hydrogen Bonding; Kinetics; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Papain; Protein Conformation; Protons; Static Electricity; Thermodynamics; Water | 2009 |
Trm13p, the tRNA:Xm4 modification enzyme from Saccharomyces cerevisiae is a member of the Rossmann-fold MTase superfamily: prediction of structure and active site.
Topics: Amino Acid Sequence; Catalytic Domain; Cysteine; Histidine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; RNA, Transfer; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; tRNA Methyltransferases | 2010 |
Influence of nickel stress on growth and some important physiological/biochemical attributes in some diverse canola (Brassica napus L.) cultivars.
Topics: Brassica napus; Cysteine; Drug Resistance; Histidine; Nickel; Osmosis; Plant Leaves; Plant Shoots; Serine; Water | 2009 |
The yeast iron regulatory proteins Grx3/4 and Fra2 form heterodimeric complexes containing a [2Fe-2S] cluster with cysteinyl and histidyl ligation.
Topics: Cysteine; Dimerization; Enzyme Stability; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Glutaredoxins; Histidine; Intracellular Signaling Peptides and Proteins; Iron-Sulfur Proteins; Ligands; Multiprotein Complexes; Mutagenesis, Site-Directed; Oxidoreductases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
Continuous-wave and pulsed EPR characterization of the [2Fe-2S](Cys)3(His)1 cluster in rat MitoNEET.
Topics: Amino Acid Sequence; Animals; Cysteine; Electron Spin Resonance Spectroscopy; Histidine; Mitochondrial Proteins; Molecular Sequence Data; Protein Structure, Tertiary; Rats | 2009 |
Repair of O6-methylguanine to guanine by cysteine in the absence and presence of histidine and by cysteine thiolate anion: a quantum chemical study.
Topics: Cysteine; DNA Repair; Guanine; Histidine; Models, Molecular; Molecular Conformation; Quantum Theory; Stereoisomerism; Sulfhydryl Compounds; Thermodynamics | 2009 |
'2+1' Tricarbonyltechnetium(I) and -rhenium(I) mixed-ligand complexes with N-methylpyridine-2-carboxyamide and isocyanide or imidazole ligands-potential precursors of radiopharmaceuticals.
Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Drug Stability; Histidine; Imidazoles; Isocyanates; Ligands; Nicotinic Acids; Organometallic Compounds; Organotechnetium Compounds; Propionates; Radioisotopes; Radiopharmaceuticals; Rats; Rhenium; Technetium | 2010 |
Crystal structure and catalytic mechanism of 4-methylmuconolactone methylisomerase.
Topics: Bacterial Proteins; Catalysis; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Ferredoxins; Genomics; Histidine; Intramolecular Transferases; Isomerases; Kinetics; Lactones; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Pseudomonas; Substrate Specificity | 2009 |
Short-distance probes for protein backbone structure based on energy transfer between bimane and transition metal ions.
Topics: Algorithms; Amino Acid Sequence; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Circular Dichroism; Cysteine; Energy Transfer; Fluorescence Resonance Energy Transfer; Histidine; Metals; Protein Binding; Protein Conformation; Protein Structure, Secondary; Proteins; Reproducibility of Results | 2009 |
Isolation and functional characterization of DgZFP: a gene encoding a Cys2/His2-type zinc finger protein in chrysanthemum.
Topics: Cell Nucleus; Chrysanthemum; Cloning, Molecular; Cysteine; Gene Expression Regulation, Plant; Histidine; Nicotiana; Plant Proteins; Plants, Genetically Modified; Salt Tolerance; Sequence Analysis, DNA; Sodium Chloride; Tissue Distribution; Transcription Factors; Zinc Fingers | 2010 |
Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300.
Topics: 2,2'-Dipyridyl; Cell Line; Chelating Agents; Cysteine; E1A-Associated p300 Protein; HeLa Cells; Histidine; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Mutagenesis; p300-CBP Transcription Factors; Protein Interaction Domains and Motifs; Protein Structure, Tertiary; Transcriptional Activation; Tumor Suppressor Protein p53 | 2010 |
Aminothiol receptors for decorporation of intravenously administered (60)Co in the rat.
Topics: Administration, Oral; Animals; Antidotes; Chelating Agents; Cobalt Radioisotopes; Cysteine; Glutathione; Histidine; Injections, Intravenous; Liposomes; Male; Metabolic Clearance Rate; Rats; Rats, Inbred F344; Receptors, Cell Surface; Terrorism; Tissue Distribution | 2010 |
X-ray absorption studies of Zn(2+)-binding sites in Escherichia coli transhydrogenase and its betaH91K mutant.
Topics: Amino Acid Substitution; Aspartic Acid; Binding Sites; Cysteine; Escherichia coli Proteins; Glutamic Acid; Histidine; Models, Molecular; Mutation; NADP Transhydrogenases; Protein Binding; Protein Structure, Tertiary; Spectrometry, X-Ray Emission; Zinc | 2010 |
Binding of histidine in the (Cys)3(His)1-coordinated [2Fe-2S] cluster of human mitoNEET.
Topics: Binding Sites; Cysteine; Electron Spin Resonance Spectroscopy; Histidine; Humans; Iron; Ligands; Mitochondrial Proteins; Models, Molecular; Mutation; Nitrogen; Protein Conformation; Sulfur; Thiazolidinediones | 2010 |
A zinc-binding site by negative selection induces metallodrug susceptibility in an essential chaperonin.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Binding, Competitive; Bismuth; Chaperonin 10; Cysteine; Drug Resistance; Escherichia coli; Helicobacter pylori; Histidine; Kinetics; Molecular Sequence Data; Mutant Proteins; Oxidation-Reduction; Protein Structure, Quaternary; Protein Structure, Tertiary; Selection, Genetic; Zinc | 2010 |
Histidine residue mediates radical-induced hinge cleavage of human IgG1.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Caspase 3; Chromatography, High Pressure Liquid; Cysteine; Electrophoresis, Capillary; Free Radicals; Histidine; Humans; Hydrogen Bonding; Immunoglobulin G; Mass Spectrometry; Molecular Conformation; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxygen; Protons | 2010 |
Efficient gene transfection by histidine-modified chitosan through enhancement of endosomal escape.
Topics: Chitosan; Cysteine; Cytosol; Disulfides; DNA; Endosomes; Gene Expression; Histidine; Hydrogen-Ion Concentration; Imidoesters; Plasmids; Rhodamines; Transfection | 2010 |
PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha.
Topics: Adaptor Proteins, Signal Transducing; Cell Adhesion; Cell Survival; Cysteine; DNA-Binding Proteins; Extracellular Matrix; Focal Adhesions; Histidine; Humans; Integrins; LIM Domain Proteins; Membrane Proteins; Neoplasms; Phosphorylation; Protein Phosphatase 1; Proto-Oncogene Proteins c-akt; Radiation Tolerance | 2010 |
Identification of protein stability determinants in chloroplasts.
Topics: Amino Acid Sequence; Amino Acids; Aminopeptidases; Chloroplasts; Cysteine; Escherichia coli; Green Fluorescent Proteins; Histidine; Methionyl Aminopeptidases; Nicotiana; Plant Proteins; Plants, Genetically Modified; Protein Biosynthesis; Protein Stability; Protein Transport; Recombinant Fusion Proteins; Ribosomal Proteins; Transcription, Genetic | 2010 |
Inhibitory regulation of acid-sensing ion channel 3 by zinc.
Topics: Acid Sensing Ion Channels; Animals; Calcium; CHO Cells; Cricetinae; Cricetulus; Cysteine; Dose-Response Relationship, Drug; Extracellular Space; Histidine; Hydrogen-Ion Concentration; Nerve Tissue Proteins; Patch-Clamp Techniques; Protein Binding; Rats; Sodium Channels; Zinc | 2010 |
NMR characterization of foldedness for the production of E3 RING domains.
Topics: Chromatography, Affinity; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Histidine; Humans; Imidazoles; Magnetic Resonance Spectroscopy; Protein Folding; Protein Stability; Recombinant Fusion Proteins; RING Finger Domains; Solubility; Ubiquitin-Protein Ligases; Zinc | 2010 |
Prevalence of H63D, S65C, and C282Y hereditary hemochromatosis gene variants in Madeira Island (Portugal).
Topics: Adolescent; Adult; Amino Acid Substitution; Aspartic Acid; Cysteine; Gene Frequency; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Male; Membrane Proteins; Polymorphism, Single Nucleotide; Portugal; Prevalence; Serine; Tyrosine; Young Adult | 2011 |
Photophysics and photochemistry of the UV filter kynurenine covalently attached to amino acids and to a model protein.
Topics: Amino Acids; Animals; Chickens; Cysteine; Glutathione; Histidine; Humans; Kynurenine; Lasers; Light; Lysine; Molecular Structure; Muramidase; Peptides; Photochemistry; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Ultraviolet Rays | 2010 |
DNA/ligand/ion-based ensemble for fluorescence turn on detection of cysteine and histidine with tunable dynamic range.
Topics: Benzothiazoles; Cysteine; DNA; Fluorescent Dyes; Histidine; Ions; Ligands; Metals; Quinolines; Spectrometry, Fluorescence | 2010 |
Insights into the mechanism of dihydropyrimidine dehydrogenase from site-directed mutagenesis targeting the active site loop and redox cofactor coordination.
Topics: Amino Acid Substitution; Animals; Arginine; Catalytic Domain; Cysteine; Dihydrouracil Dehydrogenase (NADP); Electron Spin Resonance Spectroscopy; Flavin-Adenine Dinucleotide; Flavins; Glutamine; Histidine; Hydrogen-Ion Concentration; Iron; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyrimidines; Serine; Spectrophotometry; Swine | 2010 |
Metal binding to a zinc-finger peptide: a comparison between solution and the gas phase.
Topics: Calcium; Cobalt; Copper; Cysteine; Gases; Histidine; Models, Molecular; Molecular Dynamics Simulation; Peptides; Solutions; Zinc; Zinc Fingers | 2011 |
A novel secretory poly-cysteine and histidine-tailed metalloprotein (Ts-PCHTP) from Trichinella spiralis (Nematoda).
Topics: Amino Acid Sequence; Animals; Base Sequence; Chromatography, Gel; Circular Dichroism; Cysteine; DNA Primers; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Glycosylation; Histidine; Host-Parasite Interactions; Metalloproteins; Microscopy, Electron, Transmission; Molecular Sequence Data; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trichinella spiralis | 2010 |
In situ green synthesis of biocompatible ginseng capped gold nanoparticles with remarkable stability.
Topics: Biocompatible Materials; Cell Line, Tumor; Chlorides; Cysteine; Gold; Gold Compounds; Histidine; Humans; Hydrogen-Ion Concentration; Materials Testing; Metal Nanoparticles; Microscopy, Electron, Transmission; Models, Chemical; Nanoparticles; Nanotechnology; Panax; Phytotherapy; Salts; Sodium Chloride | 2011 |
The axial methionine ligand may control the redox reorganizations in the active site of blue copper proteins.
Topics: Algorithms; Carrier Proteins; Catalytic Domain; Copper; Cysteine; Cytochromes f; Electron Transport; Histidine; Ligands; Methionine; Molecular Dynamics Simulation; Nitrogen; Oxidation-Reduction; Plastocyanin; Sulfur | 2010 |
Analysis of interactions of brevetoxin-B and human serum albumin by liquid chromatography/mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Chymotrypsin; Cysteine; Dinoflagellida; Histidine; Humans; Marine Toxins; Mass Spectrometry; Oxocins; Pronase; Protein Binding; Serum Albumin; Trypsin | 2011 |
Post-translational His-Cys cross-linkage formation in tyrosinase induced by copper(II)-peroxo species.
Topics: Aspergillus oryzae; Biocatalysis; Copper; Cross-Linking Reagents; Cysteine; Histidine; Models, Molecular; Monophenol Monooxygenase; Organometallic Compounds; Protein Conformation; Protein Processing, Post-Translational | 2011 |
Radiolabeling of rituximab with (188)Re and (99m)Tc using the tricarbonyl technology.
Topics: Animals; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Autoradiography; Cell Line, Tumor; Cysteine; Drug Stability; Female; Histidine; Humans; Isotope Labeling; Lymphoma, Non-Hodgkin; Mice; Organotechnetium Compounds; Radioisotopes; Rhenium; Rituximab | 2011 |
Radiolabeling of fab and f(ab')2 antibody fragments with 99mTc(I) tricarbonyl core using a new bifunctional tridentate ligand.
Topics: Cell Line; Chelating Agents; Cysteine; Histidine; Humans; Immunoconjugates; Immunoglobulin Fab Fragments; Isotope Labeling; Ligands; Molecular Structure; Phenols; Radiopharmaceuticals; Receptors, Immunologic; Technetium | 2011 |
Comparison between α- and β-carbonic anhydrases: can Zn(His)3(H2O) and Zn(His)(Cys)2(H2O) sites lead to equivalent enzymes?
Topics: Binding Sites; Carbonic Anhydrases; Cysteine; Histidine; Protein Structure, Tertiary; Thermodynamics; Water; Zinc | 2011 |
Horseradish peroxidase compound I as a tool to investigate reactive protein-cysteine residues: from quantification to kinetics.
Topics: Animals; Chemistry, Analytic; Cloning, Molecular; Cysteine; Escherichia coli; Gammaproteobacteria; Gene Expression; Histidine; Horseradish Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Oligopeptides; Oxidation-Reduction; Oxygen; Peroxiredoxins; Peroxynitrous Acid; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Spectrophotometry | 2011 |
Cobalt cystathionine β-synthase: a cobalt-substituted heme protein with a unique thiolate ligation motif.
Topics: Circular Dichroism; Cloning, Molecular; Cobalt; Coordination Complexes; Cystathionine beta-Synthase; Cysteine; Escherichia coli; Heme; Hemeproteins; Histidine; Humans; Hydrogen-Ion Concentration; Ligands; Models, Molecular; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry, Atomic | 2011 |
Use of a HEHEHE purification tag instead of a hexahistidine tag improves biodistribution of affibody molecules site-specifically labeled with (99m)Tc, (111)In, and (125)I.
Topics: Animals; Cell Line; Cell Line, Tumor; Cysteine; Female; Glutamic Acid; Histidine; Indium Radioisotopes; Iron Radioisotopes; Liver; Mice; Oligopeptides; Organotechnetium Compounds; Radioisotopes; Receptor, ErbB-2; Recombinant Fusion Proteins; Tissue Distribution | 2011 |
A comparison of methionine, histidine and cysteine in copper(I)-binding peptides reveals differences relevant to copper uptake by organisms in diverse environments.
Topics: Copper; Cysteine; Histidine; Hydrogen-Ion Concentration; Kinetics; Methionine; Oligopeptides; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2011 |
Classical Cys2His2 zinc finger peptides are rapidly oxidized by either H2O2 or O2 irrespective of metal coordination.
Topics: Cysteine; DNA; Histidine; Hydrogen Peroxide; Oxidation-Reduction; Oxygen; Peptides; Zinc Fingers | 2011 |
MetalDetector v2.0: predicting the geometry of metal binding sites from protein sequence.
Topics: Binding Sites; Cysteine; Histidine; Internet; Metalloproteins; Metals; Sequence Analysis, Protein; Software | 2011 |
Elucidation of the protonation states of the catalytic residues in mtKasA: implications for inhibitor design.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Alanine; Antitubercular Agents; Catalytic Domain; Cell Wall; Crystallography, X-Ray; Cysteine; Drug Design; Energy Metabolism; Enzyme Inhibitors; Histidine; Molecular Dynamics Simulation; Mycobacterium tuberculosis; Protein Conformation; Protons | 2011 |
Zinc to cadmium replacement in the A. thaliana SUPERMAN Cys₂ His₂ zinc finger induces structural rearrangements of typical DNA base determinant positions.
Topics: Arabidopsis; Arabidopsis Proteins; Base Pairing; Base Sequence; Cadmium; Cysteine; DNA Primers; DNA, Plant; Histidine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Spectrophotometry, Ultraviolet; Transcription Factors; Zinc; Zinc Fingers | 2011 |
Adsorption of amino acids (ALA, CYS, HIS, MET) on zeolites: fourier transform infrared and Raman spectroscopy investigations.
Topics: Adsorption; Alanine; Amino Acids; Cysteine; Histidine; Hydrogen-Ion Concentration; Methionine; Microscopy, Electron, Scanning; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Zeolites | 2011 |
Identification of a novel function for the FtsL cell division protein from Escherichia coli K12.
Topics: Amino Acid Sequence; Cell Cycle Proteins; Consensus Sequence; Cysteine; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Histidine; Membrane Proteins; Molecular Sequence Data; Zinc | 2011 |
Identification of a chemoreceptor zinc-binding domain common to cytoplasmic bacterial chemoreceptors.
Topics: Amino Acid Motifs; Bacterial Proteins; Chemotaxis; Cloning, Molecular; Cyclic GMP; Cysteine; Cytoplasm; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Helicobacter pylori; Histidine; Mutation; Protein Binding; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Zinc | 2011 |
Role of cysteine amino acid residues in calnexin.
Topics: Calnexin; Cysteine; Disulfides; Histidine; Humans; Immunoglobulins; Molecular Chaperones; Mutagenesis, Site-Directed; Protein Disulfide-Isomerases; Protein Transport | 2012 |
Crystal structure of the Cys2His2-type zinc finger domain of human DPF2.
Topics: Amino Acid Sequence; Crystallography, X-Ray; Cysteine; DNA-Binding Proteins; Histidine; Humans; Molecular Sequence Data; Protein Folding; Transcription Factors; Zinc Fingers | 2011 |
An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Topics: Amino Acid Substitution; Copper; Crystallization; Crystallography, X-Ray; Cysteine; Histidine; Maltose-Binding Proteins; Metals; Models, Molecular; Muramidase; Mutation; Nickel; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Zinc | 2011 |
Cysteine and histidine shuffling: mixing and matching cysteine and histidine residues in zinc finger proteins to afford different folds and function.
Topics: Amino Acid Sequence; Cysteine; Histidine; Molecular Sequence Data; Oxidation-Reduction; Protein Folding; Protein Structure, Secondary; Proteins; Sequence Alignment; Zinc; Zinc Fingers | 2011 |
Versatile trifunctional chemosensor of rhodamine derivative for Zn2+, Cu2+ and His/Cys in aqueous solution and living cells.
Topics: Coloring Agents; Copper; Cysteine; HeLa Cells; Histidine; Humans; Molecular Structure; Rhodamines; Solutions; Stereoisomerism; Water; Zinc | 2011 |
Sites of ubiquitin attachment in Saccharomyces cerevisiae.
Topics: Affinity Labels; Binding Sites; Cysteine; Histidine; Mass Spectrometry; Peptides; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ubiquitin; Ubiquitin-Conjugating Enzymes; Ubiquitination | 2012 |
Characterization of Zn(II)-responsive ribosomal proteins YkgM and L31 in E. coli.
Topics: ATP-Binding Cassette Transporters; Cysteine; Escherichia coli; Escherichia coli Proteins; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Histidine; Models, Molecular; Mutagenesis, Site-Directed; Oligonucleotide Array Sequence Analysis; Protein Binding; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Proteins; Time Factors; X-Ray Absorption Spectroscopy; Zinc | 2012 |
Characterization of oxidation products from 1-palmitoyl-2-linoleoyl-sn-glycerophosphatidylcholine in aqueous solutions and their reactions with cysteine, histidine and lysine residues.
Topics: Amino Acid Sequence; Cysteine; Histidine; Lipid Peroxidation; Lysine; Molecular Sequence Data; Oxidation-Reduction; Peptides; Phosphatidylcholines | 2012 |
Cysteine, histidine and glycine exhibit anti-inflammatory effects in human coronary arterial endothelial cells.
Topics: Anti-Inflammatory Agents; Arteritis; Cells, Cultured; Coronary Vessels; Cysteine; Drug Evaluation, Preclinical; E-Selectin; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Glycine; Histidine; Humans; I-kappa B Proteins; Interleukin-6; NF-kappa B; NF-KappaB Inhibitor alpha; Tumor Necrosis Factor-alpha | 2012 |
Uptake of dissolved organic carbon-complexed ⁶⁵Cu by the green mussel Perna viridis.
Topics: Animals; Benzopyrans; Biological Availability; Bivalvia; Carbon; Copper; Cysteine; Ditiocarb; Environmental Monitoring; Histidine; Isotopes; Spirulina; Water Pollutants, Chemical | 2012 |
Effects of the bHLH domain on axial coordination of heme in the PAS-A domain of neuronal PAS domain protein 2 (NPAS2): conversion from His119/Cys170 coordination to His119/His171 coordination.
Topics: Cysteine; Heme; Histidine; Protein Structure, Tertiary; Transcription Factors | 2012 |
Characterization of Pt-protein complexes by nHPLC-ESI-LTQ MS/MS using a gel-based bottom-up approach.
Topics: Amino Acid Sequence; Antineoplastic Agents; Binding Sites; Blood Proteins; Chromatography, High Pressure Liquid; Cisplatin; Coordination Complexes; Cysteine; Electrophoresis, Polyacrylamide Gel; Gels; Histidine; Methionine; Models, Molecular; Molecular Sequence Data; Platinum; Protein Binding; Proteolysis; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Trypsin | 2012 |
A novel variant of human superoxide dismutase 1 harboring amyotrophic lateral sclerosis-associated and experimental mutations in metal-binding residues and free cysteines lacks toxicity in vivo.
Topics: Amyotrophic Lateral Sclerosis; Animals; Binding Sites; Blotting, Northern; Cells, Cultured; Copper; Cysteine; HEK293 Cells; Histidine; Humans; Immunohistochemistry; Metals; Mice; Mice, Transgenic; Mutation; Polymerase Chain Reaction; RNA, Messenger; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Transfection; Zinc | 2012 |
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response.
Topics: Adaptor Proteins, Signal Transducing; Amidohydrolases; Amino Acid Sequence; Animals; Aspartic Acid; B-Cell CLL-Lymphoma 10 Protein; Biocatalysis; Caspases; Catalytic Domain; Crystallography, X-Ray; Cysteine; Diglycerides; DNA Mutational Analysis; Dysentery, Bacillary; Glutamic Acid; Glutamine; HEK293 Cells; HeLa Cells; Histidine; Humans; Immunity, Innate; Inflammation; Mice; Models, Molecular; Molecular Sequence Data; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Neoplasm Proteins; NF-kappa B; Shigella flexneri; TNF Receptor-Associated Factor 6; Ubiquitin-Conjugating Enzymes; Virulence Factors | 2012 |
Photocatalytic hydrogen evolution by a diiron hydrogenase model based on a peptide fragment of cytochrome c556 with an attached diiron carbonyl cluster and an attached ruthenium photosensitizer.
Topics: Cysteine; Cytochrome c Group; Histidine; Hydrogen; Hydrogenase; Models, Molecular; Photosensitizing Agents; Ruthenium | 2012 |
Spin delocalization over type zero copper.
Topics: Aspartic Acid; Azurin; Copper; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Electrons; Escherichia coli; Histidine; Leucine; Ligands; Magnetic Resonance Spectroscopy; Methionine; Models, Molecular; Mutation; Oxidation-Reduction; Pseudomonas aeruginosa; Recombinant Proteins | 2012 |
Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase.
Topics: Analysis of Variance; Animals; Arginine; Calreticulin; Cell Line, Transformed; Cysteine; Cytoplasm; DNA-Binding Proteins; Endoplasmic Reticulum Stress; Green Fluorescent Proteins; Histidine; Humans; Immunoprecipitation; Mice; Mutation; Neurons; Protein Disulfide-Isomerases; Regulatory Factor X Transcription Factors; RNA-Binding Protein FUS; Transcription Factor CHOP; Transcription Factors; Transfection | 2012 |
Crystal structure of DeSI-1, a novel deSUMOylase belonging to a putative isopeptidase superfamily.
Topics: Animals; Carbon-Nitrogen Lyases; Catalysis; Catalytic Domain; Conserved Sequence; Crystallization; Cysteine; Histidine; Mice; Protein Conformation | 2012 |
Purification of histidine-tagged aequorin with a reactive cysteine residue for chemical conjugations and its application for bioluminescent sandwich immunoassays.
Topics: Aequorin; alpha-Fetoproteins; Biotin; Cysteine; Histidine; Immunoassay; Luminescent Measurements; Maleimides; Models, Chemical; Recombinant Fusion Proteins; Sensitivity and Specificity; Streptavidin | 2012 |
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?
Topics: Adolescent; Adult; Aged; Aging; beta-Crystallin A Chain; Chromatography, High Pressure Liquid; Cysteine; Histidine; Humans; Lens, Crystalline; Mass Spectrometry; Methylation; Middle Aged; Protein Methyltransferases; Protein Processing, Post-Translational; Proteomics; S-Adenosylmethionine; Tissue Donors; Young Adult | 2012 |
[Re(CO)(3)](+) labelling of a novel cysteine/hexahistidine tag: insights into binding mode by liquid chromatography-mass spectrometry.
Topics: Amino Acid Sequence; Animals; Chromatography, Liquid; Cysteine; Histidine; Indicators and Reagents; Isotope Labeling; Molecular Sequence Data; Oligopeptides; Organometallic Compounds; Phosphatidylserines; Protein Structure, Tertiary; Proteolysis; Rats; Spectrometry, Mass, Electrospray Ionization; Synaptotagmin I; Technetium Compounds; Trypsin | 2012 |
The reactivity of human serum albumin toward trans-4-hydroxy-2-nonenal.
Topics: Aldehydes; Amino Acid Sequence; Cysteine; Histidine; Humans; Kinetics; Lysine; Mass Spectrometry; Molecular Sequence Data; Oxidation-Reduction; Serum Albumin; Thermodynamics | 2012 |
The cysteine 703 to isoleucine or histidine mutation of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae generates an iridal-type triterpenoid.
Topics: Amino Acid Sequence; Amino Acid Substitution; Biocatalysis; Cysteine; Histidine; Intramolecular Transferases; Isoleucine; Models, Molecular; Mutation; Protein Conformation; Saccharomyces cerevisiae; Triterpenes | 2012 |
Catalytic and structural role of a conserved active site histidine in berberine bridge enzyme.
Topics: Biocatalysis; Catalytic Domain; Conserved Sequence; Cysteine; Enzyme Stability; Histidine; Kinetics; Models, Molecular; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Oxygen; Photochemical Processes | 2012 |
Structure and function of ∆1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa.
Topics: Animals; Berberine; Cannabis; Carbon Dioxide; Crystallography, X-Ray; Cysteine; Flavin-Adenine Dinucleotide; Glutamic Acid; Histidine; Intramolecular Oxidoreductases; Mutation; Protein Structure, Tertiary; Psychotropic Drugs; Structure-Activity Relationship; Tyrosine | 2012 |
The role of amino acid residues in the active site of L-methionine γ-lyase from Pseudomonas putida.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Carbon-Sulfur Lyases; Catalytic Domain; Cysteine; Dimerization; Histidine; Hydrogen Bonding; Kinetics; Lysine; Methionine; Models, Molecular; Protein Structure, Secondary; Protein Subunits; Pseudomonas putida; Recombinant Proteins; Substrate Specificity | 2012 |
A Zn2+ specific triazole based calix[4]arene conjugate (L) as a fluorescence sensor for histidine and cysteine in HEPES buffer milieu.
Topics: Buffers; Calixarenes; Cysteine; HeLa Cells; HEPES; Histidine; Humans; Microscopy, Fluorescence; Phenols; Triazoles; Zinc | 2012 |
The CR3 motif of Rrp44p is important for interaction with the core exosome and exosome function.
Topics: Cysteine; Endoribonucleases; Exosome Multienzyme Ribonuclease Complex; Histidine; Mutation; Protein Interaction Domains and Motifs; Saccharomyces cerevisiae Proteins | 2012 |
Functionalized ZnS quantum dots as luminescent probes for detection of amino acids.
Topics: Absorption; Amino Acids; Cysteine; Histidine; Hydrogen-Ion Concentration; Luminescence; Molecular Probes; Quantum Dots; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Sulfides; Zinc Compounds | 2012 |
Multiple sensor array of Mn2+, Fe2+, Co2+, Ni2+, Cu2+, and Zn2+ complexes of a triazole linked imino-phenol based calix[4]arene conjugate for the selective recognition of Asp, Glu, Cys, and His.
Topics: Aspartic Acid; Calixarenes; Cysteine; Glutamic Acid; Histidine; Imines; Models, Molecular; Molecular Structure; Organometallic Compounds; Phenols; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Transition Elements; Triazoles | 2012 |
Myeloperoxidase-derived oxidants rapidly oxidize and disrupt zinc-cysteine/histidine clusters in proteins.
Topics: Alcohol Dehydrogenase; Binding Sites; Bromates; Catalytic Domain; Coordination Complexes; Cysteine; Histidine; Hypochlorous Acid; Kinetics; Oxidants; Oxidation-Reduction; Peroxidase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiocyanates | 2012 |
Iron-sulfur cluster coordination in the [FeFe]-hydrogenase H cluster biosynthetic factor HydF.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Clostridium acetobutylicum; Cysteine; Electron Spin Resonance Spectroscopy; Gene Expression Regulation, Bacterial; Histidine; Hydrogenase; Iron-Sulfur Proteins; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Spectrophotometry | 2012 |
G-quadruplex-based ultrasensitive and selective detection of histidine and cysteine.
Topics: Cysteine; DNA; Equipment Design; Equipment Failure Analysis; G-Quadruplexes; Histidine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2013 |
Novel short-chain analogues of somatostatin as ligands for Cu(II) ions. Role of the metal ion binding on the spatial structure of the ligand.
Topics: Cations, Divalent; Coordination Complexes; Copper; Cysteine; Histidine; Ligands; Somatostatin; Structure-Activity Relationship | 2012 |
Effects of select histidine to cysteine mutations on transcriptional regulation by Escherichia coli RcnR.
Topics: Amino Acid Sequence; Cobalt; Cysteine; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Histidine; Membrane Proteins; Molecular Sequence Data; Nickel; Point Mutation; Protein Conformation; Repressor Proteins; Sequence Alignment; Transcriptional Activation; X-Ray Absorption Spectroscopy | 2013 |
HR-MAS NMR spectroscopy of reconstructed human epidermis: potential for the in situ investigation of the chemical interactions between skin allergens and nucleophilic amino acids.
Topics: Alkanesulfonates; Allergens; Amino Acids; Carbon Isotopes; Cell Culture Techniques; Cell Line; Cysteine; Epidermis; Histidine; Humans; Methionine; Nuclear Magnetic Resonance, Biomolecular; Serum Albumin | 2013 |
Involvement of type I and type II mechanisms on the photoinactivation of non-enveloped DNA and RNA bacteriophages.
Topics: Allolevivirus; Bacteriophage T4; Cysteine; Free Radical Scavengers; Histidine; Light; Mannitol; Porphyrins; Singlet Oxygen; Sodium Azide; Time Factors; Virus Inactivation | 2013 |
Detection of drug bioactivation in vivo: mechanism of nevirapine-albumin conjugate formation in patients.
Topics: Adult; Aged; Anti-HIV Agents; Biotransformation; Cysteine; Glutathione S-Transferase pi; Histidine; HIV Infections; HIV-1; Humans; Middle Aged; Nevirapine; Protein Binding; Serum Albumin | 2013 |
The role of cysteines and histidins of the norepinephrine transporter.
Topics: Cysteine; Ethylmaleimide; Fluoxetine; HEK293 Cells; Histidine; Humans; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Subcellular Fractions | 2013 |
Novel structure--function information on biogenic amine transporters revealed by site-directed mutagenesis and alkylation.
Topics: Cysteine; Histidine; Humans; Norepinephrine Plasma Membrane Transport Proteins | 2013 |
In-cell covalent labeling of reactive His-tag fused proteins.
Topics: Acetamides; Cell Line, Tumor; Cysteine; Escherichia coli; Fluorescent Dyes; Green Fluorescent Proteins; HeLa Cells; Histidine; Humans; Kinetics; Nickel; Oligopeptides; Protein Interaction Maps; Recombinant Fusion Proteins; Tacrolimus Binding Protein 1A | 2013 |
Structural and biochemical characterization of an active arylamine N-acetyltransferase possessing a non-canonical Cys-His-Glu catalytic triad.
Topics: Amino Acid Sequence; Arylamine N-Acetyltransferase; Bacillus cereus; Base Sequence; Catalytic Domain; Crystallography, X-Ray; Cysteine; DNA Primers; Glutamic Acid; Histidine; Models, Molecular; Molecular Sequence Data; Polymerase Chain Reaction; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid | 2013 |
Kinetics of reversible reductive carbonylation of heme in human cystathionine β-synthase.
Topics: Carbon Monoxide; Cystathionine beta-Synthase; Cysteine; Heme; Histidine; Humans; Kinetics; Ligands; Oxygen; Protein Binding; Protein Carbonylation; Signal Transduction; Spectrum Analysis, Raman; Sulfur Dioxide; Superoxides | 2013 |
The [NiFe]-hydrogenase accessory chaperones HypC and HybG of Escherichia coli are iron- and carbon dioxide-binding proteins.
Topics: Carbon Dioxide; Carrier Proteins; Cysteine; Escherichia coli; Escherichia coli Proteins; Histidine; Hydrogen Peroxide; Hydrogenase; Iron; Ligands; Molecular Chaperones; Oxidation-Reduction; Oxygen | 2013 |
Locating Pb2+ and Zn2+ in zinc finger-like peptides using mass spectrometry.
Topics: Cysteine; Histidine; Lead; Oligopeptides; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Zinc; Zinc Fingers | 2013 |
Fine modulation of the respiratory syncytial virus M2-1 protein quaternary structure by reversible zinc removal from its Cys(3)-His(1) motif.
Topics: Amino Acid Motifs; Cysteine; Histidine; Humans; Hydrogen-Ion Concentration; Protein Structure, Quaternary; Respiratory Syncytial Virus, Human; Viral Proteins; Zinc | 2013 |
Regioselectivity of the oxidative C-S bond formation in ergothioneine and ovothiol biosyntheses.
Topics: Betaine; Carbon-Sulfur Ligases; Catalysis; Cysteine; Ergothioneine; Histidine; Methylhistidines; Molecular Structure; Oxidation-Reduction; Stereoisomerism; Sulfhydryl Compounds | 2013 |
Combined effects of polymorphisms of DNA-repair protein genes and metabolic enzyme genes on the risk of cholangiocarcinoma.
Topics: Alanine; Arginine; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Cysteine; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; Genotype; Glutamine; Glutathione Transferase; Histidine; Humans; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors; Serine; Valine; X-ray Repair Cross Complementing Protein 1 | 2013 |
The pivotal role of copper(II) in the enantiorecognition of tryptophan and histidine by gold nanoparticles.
Topics: Cations, Divalent; Chemical Fractionation; Copper; Cysteine; Gold; Histidine; Light; Nanoparticles; Scattering, Radiation; Spectrophotometry; Stereoisomerism; Tryptophan | 2014 |
Synthesis of petal-like ferric oxide/cysteine architectures and their application in affinity separation of proteins.
Topics: Arabidopsis Proteins; Chromatography, Affinity; Cysteine; Electrophoresis, Polyacrylamide Gel; Ferric Compounds; Histidine; Microscopy, Electron, Scanning; Oligopeptides; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Sulfhydryl Compounds; Thermogravimetry; X-Ray Diffraction | 2014 |
Alternative chelating agents: evaluation of the ready biodegradability and complexation properties.
Topics: Biodegradation, Environmental; Chelating Agents; Cysteine; Ethylenediamines; Histidine; Imidazoles; Metals; Picolinic Acids; Pyridines | 2014 |
Using low-frequency IR spectra for the unambiguous identification of metal ion-ligand coordination sites in purpose-built complexes.
Topics: Coordination Complexes; Cysteine; Histidine; Imidazoles; Ions; Ligands; Malonates; Metals; Propylamines; Spectrophotometry, Infrared | 2014 |
Dynamics of reactive oxygen species generation in the presence of copper(II)-histidine complex and cysteine.
Topics: Copper; Cysteine; DNA Damage; Histidine; Hydrogen Peroxide; Organometallic Compounds; Oxygen; Reactive Oxygen Species | 2013 |
The CcmFH complex is the system I holocytochrome c synthetase: engineering cytochrome c maturation independent of CcmABCDE.
Topics: Amino Acid Sequence; Amino Acid Substitution; Conserved Sequence; Cysteine; Cytochromes c; Escherichia coli; Escherichia coli Proteins; Heme; Histidine; Lyases; Molecular Sequence Data; Multiprotein Complexes; Protein Engineering | 2014 |
The ββα fold of zinc finger proteins as a "natural" protecting group. Chemoselective synthesis of a DNA-binding zinc finger derivative.
Topics: Binding Sites; Chromatography, High Pressure Liquid; Cysteine; DNA; Histidine; Molecular Structure; Protein Engineering; Protein Folding; Zinc Fingers | 2014 |
Linear short histidine and cysteine modified arginine peptides constitute a potential class of DNA delivery agents.
Topics: Animals; Apoptosis; Arginine; Cell Proliferation; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Cysteine; DNA; Drug Delivery Systems; Endosomes; Flow Cytometry; Gene Transfer Techniques; HeLa Cells; Histidine; Humans; MCF-7 Cells; Microscopy, Atomic Force; Peptide Fragments; Transfection | 2014 |
Defining membrane spanning domains and crucial membrane-localized acidic amino acid residues for K⁺ transport of a Kup/HAK/KT-type Escherichia coli potassium transporter.
Topics: Amino Acid Sequence; Amino Acid Substitution; Biological Transport; Cell Membrane; Cysteine; Escherichia coli; Escherichia coli Proteins; Histidine; Hydrogen-Ion Concentration; Molecular Sequence Data; Potassium; Protein Structure, Tertiary; Serine | 2014 |
Bachem - insights into peptide chemistry achievements by the world's leading independent manufacturer of peptides.
Topics: Chromatography, High Pressure Liquid; Cysteine; Histidine; Peptides; Stereoisomerism | 2013 |
A Sco protein among the hypothetical proteins of Bacillus lehensis G1: Its 3D macromolecular structure and association with Cytochrome C Oxidase.
Topics: Amino Acid Sequence; Bacillus; Bacterial Proteins; Binding Sites; Copper; Cysteine; Databases, Genetic; Electron Transport Complex IV; Histidine; Membrane Proteins; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Protein Structure, Secondary; Sequence Alignment | 2014 |
Cysteine oxidation reactions catalyzed by a mononuclear non-heme iron enzyme (OvoA) in ovothiol biosynthesis.
Topics: Betaine; Catalysis; Cysteine; Cysteine Dioxygenase; Heme; Histidine; Humans; Methylhistidines; Models, Biological; Molecular Structure; Mycobacterium smegmatis; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction | 2014 |
Comparative thermodynamic analysis of zinc binding to the His/Cys motif in virion infectivity factor.
Topics: Amino Acid Motifs; Amino Acid Sequence; Cysteine; Histidine; Molecular Sequence Data; Sequence Homology, Amino Acid; Thermodynamics; Ultracentrifugation; vif Gene Products, Human Immunodeficiency Virus; Zinc | 2014 |
Mechanism of oxidant-induced mistranslation by threonyl-tRNA synthetase.
Topics: Cysteine; Escherichia coli Proteins; Histidine; Hydrogen Peroxide; Oxidants; Oxidative Stress; Peptide Elongation Factor Tu; RNA, Transfer, Thr; Serine; Sulfenic Acids; Threonine-tRNA Ligase; Transfer RNA Aminoacylation | 2014 |
Murein lytic enzyme TgaA of Bifidobacterium bifidum MIMBb75 modulates dendritic cell maturation through its cysteine- and histidine-dependent amidohydrolase/peptidase (CHAP) amidase domain.
Topics: Amidohydrolases; Animals; Basic Helix-Loop-Helix Transcription Factors; Bifidobacterium; Cell Differentiation; Cell Wall; Cells, Cultured; Cysteine; Dendritic Cells; Histidine; Membrane Proteins; Mice, Inbred C57BL; Peptidoglycan | 2014 |
The Cys78-Asn88 loop region of the Campylobacter jejuni CstII is essential for α2,3-sialyltransferase activity: analysis of the His85 mutants.
Topics: Asparagine; Campylobacter jejuni; Cysteine; Enzyme Activation; Enzyme Stability; Histidine; Mutation; Sialyltransferases; Temperature | 2014 |
A role for hydrogen bonding in DNA recognition by the non-classical CCHHC type zinc finger, NZF-1.
Topics: Animals; Binding Sites; Cysteine; DNA; Histidine; Humans; Hydrogen Bonding; Models, Molecular; Mutation; Nerve Tissue Proteins; Transcription Factors; Zinc Fingers | 2014 |
The intrinsic cysteine and histidine residues of the anti-Salmonella antibody Se155-4: a model for the introduction of new functions into antibody-binding sites.
Topics: Antibodies, Bacterial; Binding Sites, Antibody; Copper; Cysteine; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Fluorescent Dyes; Histidine; Hydrogen-Ion Concentration; Models, Molecular; Protein Engineering; Recombinant Proteins; Salmonella | 2014 |
Cysteine-mediated dynamic hydrogen-bonding network in the active site of Pin1.
Topics: Amino Acid Sequence; Biocatalysis; Catalytic Domain; Conserved Sequence; Cysteine; Databases, Protein; Histidine; Humans; Hydrogen Bonding; Models, Molecular; Molecular Dynamics Simulation; NIMA-Interacting Peptidylprolyl Isomerase; Oligopeptides; Peptidylprolyl Isomerase; Phosphorylation; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; Protons; Reproducibility of Results; Thermodynamics | 2014 |
SOD1 oxidation and formation of soluble aggregates in yeast: relevance to sporadic ALS development.
Topics: Amyotrophic Lateral Sclerosis; Chromatography, High Pressure Liquid; Cysteine; Green Fluorescent Proteins; Histidine; Humans; Mutation; Oxidation-Reduction; Protein Folding; Protein Processing, Post-Translational; Protein Stability; Recombinant Fusion Proteins; Recombinant Proteins; Saccharomyces cerevisiae; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase; Superoxide Dismutase-1 | 2014 |
Protein delivery using Cys2-His2 zinc-finger domains.
Topics: Amino Acid Sequence; Cell Line; Cysteine; Histidine; Humans; Models, Molecular; Molecular Sequence Data; Proteins; Zinc Fingers | 2014 |
Genetically encoding an electrophilic amino acid for protein stapling and covalent binding to native receptors.
Topics: Amino Acyl-tRNA Synthetases; Cross-Linking Reagents; Cysteine; Histidine; Humans; Lysine; Methanosarcina; Myoglobin; Protein Binding; Protein Conformation; Protein Engineering; Receptor, ErbB-2; Recombinant Proteins | 2014 |
A novel fluorescence probe for estimation of cysteine/histidine in human blood plasma and recognition of endogenous cysteine in live Hct116 cells.
Topics: Colorectal Neoplasms; Coordination Complexes; Copper; Cysteine; Fluorescence; Fluorescent Dyes; HCT116 Cells; Histidine; Humans; Luminescent Measurements | 2014 |
Biochemical and biophysical characterization of PlyGRCS, a bacteriophage endolysin active against methicillin-resistant Staphylococcus aureus.
Topics: Bacteriophages; Biofilms; Catalytic Domain; Cell Wall; Circular Dichroism; Cloning, Molecular; Cysteine; Endopeptidases; Histidine; Methicillin-Resistant Staphylococcus aureus; Mutagenesis, Site-Directed; N-Acetylmuramoyl-L-alanine Amidase; Staphylococcus epidermidis | 2015 |
Zinc binding directly regulates tau toxicity independent of tau hyperphosphorylation.
Topics: Animals; Cysteine; Drosophila; Histidine; Humans; Mutation; Phosphorylation; Protein Aggregation, Pathological; Protein Binding; tau Proteins; Tauopathies; Zinc | 2014 |
Mechanisms of mitochondrial holocytochrome c synthase and the key roles played by cysteines and histidine of the heme attachment site, Cys-XX-Cys-His.
Topics: Binding Sites; Catalytic Domain; Conserved Sequence; Cysteine; Cytochromes c; Escherichia coli; Heme; Histidine; Humans; Ligands; Lyases; Mitochondria; Oligonucleotides; Plasmids; Protein Folding; Pyridines; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Sulfhydryl Compounds | 2014 |
Evidence for substrate binding-induced zwitterion formation in the catalytic Cys-His dyad of the SARS-CoV main protease.
Topics: Catalytic Domain; Coronavirus 3C Proteases; Cysteine; Cysteine Endopeptidases; Entropy; Histidine; Models, Molecular; Molecular Dynamics Simulation; Static Electricity; Substrate Specificity; Viral Proteins | 2014 |
Immobilized palladium(II) ion affinity chromatography for recovery of recombinant proteins with peptide tags containing histidine and cysteine.
Topics: Chromatography, Affinity; Cysteine; Escherichia coli; Green Fluorescent Proteins; Histidine; Humans; Palladium; Peptide Fragments; Recombinant Proteins | 2014 |
Exploring advantages/disadvantages and improvements in overcoming gene delivery barriers of amino acid modified trimethylated chitosan.
Topics: Active Transport, Cell Nucleus; Animals; Arginine; Chitosan; Cysteine; Endocytosis; Endosomes; Gene Expression Regulation; Genes, Reporter; Green Fluorescent Proteins; HEK293 Cells; Histidine; Humans; Mice; Muscle, Skeletal; Nanoparticles; Nucleic Acid Conformation; Plasmids; Polyphosphates; Time Factors; Transfection | 2015 |
Pathophysiologic Changes in Extracellular pH Modulate Parathyroid Calcium-Sensing Receptor Activity and Secretion via a Histidine-Independent Mechanism.
Topics: Acidosis; Alkalosis; Animals; Cattle; Cysteine; Extracellular Signal-Regulated MAP Kinases; HEK293 Cells; Histidine; Humans; Hydrogen-Ion Concentration; Parathyroid Glands; Parathyroid Hormone; Phosphorylation; Receptors, Calcium-Sensing | 2015 |
A systematic survey of the Cys2His2 zinc finger DNA-binding landscape.
Topics: Binding Sites; Cysteine; Data Collection; DNA; Histidine; Zinc Fingers | 2015 |
Sensitive detection of biothiols and histidine based on the recovered fluorescence of the carbon quantum dots-Hg(II) system.
Topics: Biosensing Techniques; Cysteine; Glutathione; Histidine; Humans; Limit of Detection; Mercury; Quantum Dots; Spectrometry, Fluorescence | 2015 |
Integrated logic gate for fluorescence turn-on detection of histidine and cysteine based on Ag/Au bimetallic nanoclusters-Cu²⁺ ensemble.
Topics: Biosensing Techniques; Copper; Cysteine; Fluorescence; Gold; Histidine; Humans; Nanostructures; Silver | 2015 |
Analysis of cysteine and histidine residues required for zinc response of the transcription factor human MTF-1.
Topics: Amino Acid Substitution; Animals; Cell Line; Cysteine; DNA-Binding Proteins; Histidine; Humans; Mice; Mutation; Transcription Factor MTF-1; Transcription Factors; Zinc | 2015 |
Fate of zinc and silver engineered nanoparticles in sewerage networks.
Topics: Biofilms; Cysteine; Histidine; Metal Nanoparticles; Silver; Sulfides; Waste Disposal, Fluid; Wastewater; X-Ray Absorption Spectroscopy; Zinc Oxide | 2015 |
Direct protein delivery to mammalian cells using cell-permeable Cys2-His2 zinc-finger domains.
Topics: Amino Acid Sequence; Base Sequence; Cell Membrane Permeability; Cysteine; DNA-Binding Proteins; HeLa Cells; Histidine; Humans; Models, Molecular; Molecular Sequence Data; Proteins; Zinc Fingers | 2015 |
The large intracellular loop of hZIP4 is an intrinsically disordered zinc binding domain.
Topics: Cation Transport Proteins; Cysteine; Histidine; Humans; Intrinsically Disordered Proteins; Zinc | 2015 |
Influence of key amino acid mutation on the active site structure and on folding in acetyl-CoA synthase: a theoretical perspective.
Topics: Acetate-CoA Ligase; Aldehyde Oxidoreductases; Catalytic Domain; Cysteine; Histidine; Models, Molecular; Multienzyme Complexes; Mutation; Protein Folding | 2015 |
Molecular mechanical properties of short-sequence peptide enzyme mimics.
Topics: Acetylation; Cysteine; Enzymes; Histidine; Hydrolysis; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Molecular Mimicry; Peptides | 2016 |
A Novel ¹¹¹In-Labeled Anti-Prostate-Specific Membrane Antigen Nanobody for Targeted SPECT/CT Imaging of Prostate Cancer.
Topics: Animals; Antigens, Surface; Autoradiography; Cell Line, Tumor; Cysteine; Flow Cytometry; Glutamate Carboxypeptidase II; Histidine; Humans; Kidney; Male; Mice; Multimodal Imaging; Nanomedicine; Neoplasm Transplantation; Oligopeptides; Peptide Library; Prostatic Neoplasms; Protein Structure, Tertiary; Proto-Oncogene Proteins c-myc; Single-Domain Antibodies; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2015 |
The reaction of a platinated methionine motif of CTR1 with cysteine and histidine is dependent upon the type of precursor platinum complex.
Topics: Amino Acid Motifs; Amino Acid Sequence; Antineoplastic Agents; Binding Sites; Cation Transport Proteins; Cisplatin; Copper Transporter 1; Cysteine; Histidine; Methionine; Molecular Sequence Data; Organoplatinum Compounds; Oxaliplatin; Protein Binding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2015 |
Reactivity of a Zn(Cys)2(His)2 Zinc Finger with Singlet Oxygen: Oxidation Directed toward Cysteines but not Histidines.
Topics: Cysteine; Histidine; Magnetic Resonance Spectroscopy; Models, Molecular; Oxidation-Reduction; Peptides; Singlet Oxygen; Zinc Fingers | 2015 |
Oral delivery of shRNA based on amino acid modified chitosan for improved antitumor efficacy.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Buffers; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitosan; Cysteine; DNA; Endocytosis; Histidine; Inhibitor of Apoptosis Proteins; Intracellular Space; Mice; Nanoparticles; Particle Size; Plasmids; Polymers; Proton Magnetic Resonance Spectroscopy; RNA, Small Interfering; Static Electricity; Survivin; Treatment Outcome | 2015 |
Rhenium complexes of bidentate, bis-bidentate and tridentate N-heterocyclic carbene ligands.
Topics: Chlorides; Cysteine; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, 3-Ring; Histidine; Indicators and Reagents; Isotope Labeling; Ligands; Magnetic Resonance Spectroscopy; Methane; Models, Molecular; Oxides; Radiopharmaceuticals; Rhenium; Silver Compounds; X-Ray Diffraction | 2015 |
Comparative transcriptomic analysis of Clostridium acetobutylicum biofilm and planktonic cells.
Topics: Amino Acids; Bacterial Proteins; Biofilms; Clostridium acetobutylicum; Cysteine; Down-Regulation; Gene Expression Profiling; Glycolysis; Histidine; Iron; Metabolic Networks and Pathways; Multigene Family; Oligonucleotide Array Sequence Analysis; Sulfur; Up-Regulation | 2016 |
Colorimetric Strategy for Highly Sensitive and Selective Simultaneous Detection of Histidine and Cysteine Based on G-Quadruplex-Cu(II) Metalloenzyme.
Topics: Colorimetry; Cysteine; Enzymes; G-Quadruplexes; Histidine; Limit of Detection; Metalloproteins | 2016 |
In situ chemical behaviour of methylisothiazolinone (MI) and methylchloroisothiazolinone (MCI) in reconstructed human epidermis: a new approach to the cross-reactivity issue.
Topics: Cross Reactions; Cysteine; Epidermis; Histidine; Humans; Lysine; Magnetic Resonance Spectroscopy; Sulfhydryl Compounds; Thiazoles | 2016 |
Cloning, expression and characterization of histidine-tagged biotin synthase of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Biotin; Cloning, Molecular; Cysteine; Deoxyadenosines; Enzyme Inhibitors; Enzyme Stability; Histidine; Hydrogen-Ion Concentration; Kinetics; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Protein Engineering; Protein Multimerization; Recombinant Fusion Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Sulfurtransferases; Temperature | 2016 |
An integrated logic system for time-resolved fluorescent "turn-on" detection of cysteine and histidine base on terbium (III) coordination polymer-copper (II) ensemble.
Topics: Animals; Coordination Complexes; Copper; Cysteine; Fluorescence; Guanosine Monophosphate; Histidine; Logic; Male; Polymers; Rats; Terbium | 2016 |
Gold-plated silver nanoparticles engineered for sensitive plasmonic detection amplified by morphological changes.
Topics: Ampicillin; Anti-Bacterial Agents; Bromides; Cysteine; Gold; Histidine; Metal Nanoparticles; Silver; Surface Plasmon Resonance | 2016 |
Chloroacetamide-Linked Nucleotides and DNA for Cross-Linking with Peptides and Proteins.
Topics: Acetamides; Cysteine; DNA; Electron Transport; Histidine; Models, Molecular; Nucleic Acid Conformation; Nucleotides; Peptides; Protein Conformation; Proteins | 2016 |
The multiple conformational charge states of zinc(II) coordination by 2His-2Cys oligopeptide investigated by ion mobility-mass spectrometry, density functional theory and theoretical collision cross sections.
Topics: Cysteine; Histidine; Hydrogen-Ion Concentration; Mass Spectrometry; Models, Molecular; Oligopeptides; Protein Conformation; Zinc; Zinc Fingers | 2016 |
Structural basis of haem-iron acquisition by fungal pathogens.
Topics: Aspartic Acid; Biological Transport; Candida albicans; Crystallography, X-Ray; Cysteine; Fungal Proteins; Heme; Hemeproteins; Histidine; Iron; Membrane Proteins; Molecular Conformation | 2016 |
Validation and correction of Zn-Cys
Topics: Binding Sites; Coordination Complexes; Crystallography, X-Ray; Cysteine; Databases, Protein; Histidine; Ligands; Models, Molecular; Protein Conformation; Proteins; Zinc | 2016 |
Systemic delivery of small interfering RNA targeting nuclear factor κB in mice with collagen-induced arthritis using arginine-histidine-cysteine based oligopeptide-modified polymer nanomicelles.
Topics: Animals; Arginine; Arthritis, Experimental; Arthritis, Rheumatoid; Collagen; Cysteine; Cytokines; Disease Models, Animal; Histidine; Inflammation; Male; Mice; Mice, Inbred DBA; Micelles; Nanoparticles; NF-kappa B; Oligopeptides; Polymers; RNA, Messenger; RNA, Small Interfering; Synovial Membrane; Synoviocytes; Transcription Factor RelA | 2016 |
CO and NO bind to Fe(II) DiGeorge critical region 8 heme but do not restore primary microRNA processing activity.
Topics: Binding Sites; Carbon Monoxide; Circular Dichroism; Cysteine; Ferric Compounds; Ferrous Compounds; Heme; Histidine; Humans; Hydrogen-Ion Concentration; Ligands; Lysine; MicroRNAs; Models, Biological; Nitric Oxide; Protein Binding; RNA-Binding Proteins; Spectrum Analysis, Raman | 2016 |
Mutational analysis of Kex2 recognition sites and a disulfide bond in tannase from Aspergillus oryzae.
Topics: Aspergillus oryzae; Binding Sites; Carboxylic Ester Hydrolases; Catalysis; Crystallography, X-Ray; Cysteine; Disulfides; DNA Mutational Analysis; Fungal Proteins; Gene Deletion; Genetic Variation; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Proprotein Convertases; Serine; Substrate Specificity; Temperature | 2017 |
Crystal Structure of the Salmonella Typhimurium Effector GtgE.
Topics: Asparagine; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Cysteine; Histidine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Folding; Protein Structure, Secondary; rab GTP-Binding Proteins; Salmonella typhimurium | 2016 |
Distal [FeS]-Cluster Coordination in [NiFe]-Hydrogenase Facilitates Intermolecular Electron Transfer.
Topics: Algorithms; Bacterial Proteins; Cysteine; Desulfovibrio; Electron Transport; Electrons; Histidine; Hydrogen; Hydrogenase; Iron-Sulfur Proteins; Models, Chemical; Models, Molecular; Mutation; Oxidation-Reduction; Protein Conformation; Thermodynamics | 2017 |
Neonatal nonepileptic myoclonus is a prominent clinical feature of KCNQ2 gain-of-function variants R201C and R201H.
Topics: Anticonvulsants; Arginine; Child, Preschool; Cysteine; Electroencephalography; Female; Histidine; Humans; Infant; Infant, Newborn; KCNQ2 Potassium Channel; Magnetic Resonance Imaging; Male; Myoclonus; Phenotype; Polymorphism, Single Nucleotide; Registries; Respiration Disorders; Spasms, Infantile | 2017 |
Myroilysin Is a New Bacterial Member of the M12A Family of Metzincin Metallopeptidases and Is Activated by a Cysteine Switch Mechanism.
Topics: Bacterial Proteins; Catalytic Domain; Conserved Sequence; Crystallization; Cysteine; Enzyme Activation; Flavobacteriaceae; Histidine; Metalloendopeptidases; Metalloproteases; Molecular Structure; Zinc | 2017 |
A distal ligand mutes the interaction of hydrogen sulfide with human neuroglobin.
Topics: Catalysis; Crystallography, X-Ray; Cysteine; Electron Spin Resonance Spectroscopy; Globins; Heme; Hemoglobins; Histidine; Humans; Hydrogen Sulfide; Hydrogen-Ion Concentration; Kinetics; Ligands; Mass Spectrometry; Mutation; Myoglobin; Nerve Tissue Proteins; Neuroglobin; Oxygen; Protein Conformation; Spectrometry, Mass, Electrospray Ionization; Spectrum Analysis, Raman; Sulfides; Thiosulfates; Thrombin | 2017 |
Design of Poly-l-Glutamate-Based Complexes for pDNA Delivery.
Topics: Amides; Cell Line, Tumor; Cysteine; DNA; Epithelial Cells; Ethylenediamines; Gene Expression; Gene Transfer Techniques; Genes, Reporter; Green Fluorescent Proteins; Histidine; Humans; Luciferases; Neurons; Plasmids; Polyglutamic Acid; Succinimides | 2017 |
In-depth study of DNA binding of Cys2His2 finger domains in testis zinc-finger protein.
Topics: Animals; Cysteine; DNA; Histidine; Magnetic Resonance Spectroscopy; Male; Mice; Testis; Zinc Fingers | 2017 |
Development of a Small Hybrid Molecule That Mediates Degradation of His-Tag Fused Proteins.
Topics: Biotin; Cell Line; Cysteine; Histidine; Humans; Leupeptins; Maleimides; Nitrilotriacetic Acid; Organometallic Compounds; Proteasome Inhibitors; Proteolysis; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Smad2 Protein; Ubiquitin-Protein Ligases | 2018 |
Theoretical insights into the protonation states of active site cysteine and citrullination mechanism of Porphyromonas gingivalis peptidylarginine deiminase.
Topics: Amino Acid Motifs; Arginine; Aspartic Acid; Bacterial Proteins; Binding Sites; Catalytic Domain; Citrulline; Crystallography, X-Ray; Cysteine; Histidine; Hydrolases; Hydrolysis; Molecular Dynamics Simulation; Porphyromonas gingivalis; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein-Arginine Deiminases; Protons; Quantum Theory; Substrate Specificity; Thermodynamics | 2017 |
Discovery and Characterization of Histidine Oxidation Initiated Cross-links in an IgG1 Monoclonal Antibody.
Topics: Antibodies, Monoclonal; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine; Histidine; Immunoglobulin G; Lysine; Mass Spectrometry; Molecular Weight; Oxidation-Reduction; Peptide Mapping; Peptides | 2017 |
Mutations in Cancer Cause Gain of Cysteine, Histidine, and Tryptophan at the Expense of a Net Loss of Arginine on the Proteome Level.
Topics: Amino Acid Substitution; Arginine; Cell Line, Tumor; Codon, Nonsense; Cysteine; Histidine; Humans; Neoplasms; Proteome; Tryptophan; Tumor Suppressor Protein p53 | 2017 |
Understanding the Reactivity of CO
Topics: Amino Acids; Carbonates; Cysteine; Electron Transport; Free Radicals; Histidine; Hydrogen; Methionine; Nitric Oxide; Phenylalanine; Sulfur; Tryptophan; Tyrosine | 2017 |
Combined Biochemical, Biophysical, and Cellular Methods to Study Fe-S Cluster Transfer and Cytosolic Aconitase Repair by MitoNEET.
Topics: Aconitate Hydratase; Animals; Cysteine; Cytosol; Escherichia coli; Ferredoxins; Histidine; Humans; Iron; Iron Regulatory Protein 1; Iron-Sulfur Proteins; Mitochondrial Membranes; Mitochondrial Proteins; Nitrosative Stress; Oxidation-Reduction | 2017 |
Modification of Human Umbilical Cord Blood Stem Cells Using Polyethylenimine Combined with Modified TAT Peptide to Enhance BMP-2 Production.
Topics: Bone Morphogenetic Protein 2; Bone Regeneration; Cells, Cultured; Cysteine; Fetal Blood; Gene Products, tat; Gene Transfer Techniques; Genetic Therapy; Histidine; Humans; Mesenchymal Stem Cells; Osteogenesis; Plasmids; Polyethyleneimine; RNA, Messenger; Stem Cells; Transfection | 2017 |
Evolutionary relationship between the cysteine and histidine rich domains (CHORDs) and Btk-type zinc fingers.
Topics: Agammaglobulinaemia Tyrosine Kinase; Amino Acid Sequence; Animals; Binding Sites; Cysteine; Eukaryota; Evolution, Molecular; Histidine; Humans; Metalloproteins; Protein Structural Elements; Protein-Tyrosine Kinases; Sequence Alignment; Signal Transduction; Zinc; Zinc Fingers | 2018 |
Conserved residues are critical for Haloferax volcanii archaeosortase catalytic activity: Implications for convergent evolution of the catalytic mechanisms of non-homologous sortases from archaea and bacteria.
Topics: Amino Acid Sequence; Aminoacyltransferases; Archaea; Archaeal Proteins; Arginine; Bacteria; Bacterial Proteins; Biological Evolution; Catalysis; Catalytic Domain; Conserved Sequence; Cysteine; Cysteine Endopeptidases; Evolution, Molecular; Haloferax volcanii; Histidine; Protein Processing, Post-Translational | 2018 |
Distribution and speciation of zinc in the gills of rainbow trout (Oncorhynchus mykiss) during acute waterborne zinc exposure: Interactions with cadmium or copper.
Topics: Animals; Cadmium; Calcium; Copper; Cysteine; Drug Interactions; Gills; Histidine; Microscopy, Fluorescence; Mitochondria; Oncorhynchus mykiss; Organometallic Compounds; Phosphates; Spectrometry, X-Ray Emission; Sulfur; Tissue Distribution; Toxicity Tests, Acute; Toxicokinetics; Water Pollutants, Chemical; X-Ray Absorption Spectroscopy; Zinc; Zinc Compounds | 2018 |
Intra-electron transfer induced by protonation in copper-containing nitrite reductase.
Topics: Aspartic Acid; Catalytic Domain; Copper; Crystallography, X-Ray; Cysteine; Electrons; Histidine; Kinetics; Nitrite Reductases; Nitrites; Oxidation-Reduction; Protein Conformation; Protons | 2018 |
A mass spectrometry approach for the identification and localization of small aldehyde modifications of proteins.
Topics: Acrolein; Aldehydes; Chromatography, Liquid; Cysteine; Histidine; Humans; Lysine; Muramidase; Oxidation-Reduction; Peptide Fragments; Serum Albumin, Human; Tandem Mass Spectrometry | 2018 |
The structure of urease inactivated by Ag(i): a new paradigm for enzyme inhibition by heavy metals.
Topics: Anti-Infective Agents; Calorimetry; Catalytic Domain; Cysteine; Enzyme Inhibitors; Histidine; Kinetics; Methionine; Models, Molecular; Nickel; Silver; Sporosarcina; Urease; Virulence Factors | 2018 |
Molecular switch-modulated fluorescent copper nanoclusters for selective and sensitive detection of histidine and cysteine.
Topics: Biosensing Techniques; Chemistry Techniques, Analytical; Copper; Cysteine; DNA; Fluorescent Dyes; Histidine; Humans; Limit of Detection; Microscopy, Electron, Transmission; Nanostructures | 2018 |
Elucidation of chemical modifier reactivity towards peptides and proteins and the analysis of specific fragmentation by matrix-assisted laser desorption/ionization collision-induced dissociation tandem mass spectrometry.
Topics: Binding Sites; Cysteine; Histidine; Lipoxygenase; Lipoxygenase Inhibitors; Peptide Fragments; Peptides; Protein Binding; Proteins; Quinones; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2019 |
A single domain antibody against the Cys- and His-rich domain of PCSK9 and evolocumab exhibit different inhibition mechanisms in humanized PCSK9 mice.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cysteine; Genotype; Histidine; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; PCSK9 Inhibitors; Proprotein Convertase 9 | 2018 |
Recognition of protein biomarkers using epitope-mediated molecularly imprinted films: Histidine or cysteine modified epitopes?
Topics: Biomarkers; Biomimetic Materials; Biosensing Techniques; Cysteine; Epitopes; Histidine; Molecular Imprinting; Peptides; Phosphopyruvate Hydratase; Polymers | 2019 |
An On-Off-On Fluorescence Probe Based on Coumarin for Cu
Topics: A549 Cells; Biosensing Techniques; Copper; Coumarins; Cysteine; Fluorescence; Fluorescent Dyes; Histidine; Humans; Limit of Detection; Quantum Dots; Reproducibility of Results; Schiff Bases; Spectrometry, Fluorescence | 2019 |
Gram-scale fermentative production of ergothioneine driven by overproduction of cysteine in Escherichia coli.
Topics: Apoproteins; Bacterial Proteins; Batch Cell Culture Techniques; Cysteine; Ergothioneine; Escherichia coli; Escherichia coli Proteins; Glucose; Glutamate-Cysteine Ligase; Histidine; Metabolic Engineering; Methionine; Mycobacterium smegmatis; Repressor Proteins | 2019 |
An efficient, step-economical strategy for the design of functional metalloproteins.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Cytochrome b Group; Disulfides; Escherichia coli; Escherichia coli Proteins; Histidine; Metalloproteins; Metals, Heavy; Mutation; Nitric Oxide; Protein Binding; Protein Engineering | 2019 |
Metabolomic study reveals the acute hypotensive effect of S-1-propenylcysteine accompanied by alteration of the plasma histidine level in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Chromatography, Liquid; Cysteine; Discriminant Analysis; Histidine; Hypertension; Least-Squares Analysis; Male; Mass Spectrometry; Metabolomics; Rats; Rats, Inbred SHR; Receptors, Histamine H3; Time Factors | 2019 |
Protein Arginine Deiminases (PADs): Biochemistry and Chemical Biology of Protein Citrullination.
Topics: Animals; Aspartic Acid; Catalysis; Catalytic Domain; Citrullination; Cysteine; Enzyme Inhibitors; HEK293 Cells; Histidine; Humans; Mice; Models, Chemical; Mutation; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Proteins | 2019 |
Analysis of Single-Nucleotide Polymorphisms in Human Voltage-Gated Ion Channels.
Topics: Amino Acid Sequence; Arginine; Calcium Channels; Channelopathies; Cysteine; Databases, Protein; Gene Expression; Glutamine; Histidine; Humans; Ion Channel Gating; Models, Molecular; Polymorphism, Single Nucleotide; Potassium Channels, Voltage-Gated; Protein Conformation; Protein Domains; Proteomics; Voltage-Gated Sodium Channels | 2019 |
l-Histidine, arachidonic acid, biliverdin, and l-cysteine-glutathione disulfide as potential biomarkers for cured pulmonary tuberculosis.
Topics: Arachidonic Acid; Biliverdine; Biomarkers; Case-Control Studies; Cysteine; Discriminant Analysis; Female; Glutathione; Histidine; Humans; Least-Squares Analysis; Male; Metabolome; Middle Aged; ROC Curve; Tuberculosis, Pulmonary | 2019 |
Weak Acid-Base Interactions of Histidine and Cysteine Affect the Charge States, Tertiary Structure, and Zn(II)-Binding of Heptapeptides.
Topics: Cysteine; Histidine; Mass Spectrometry; Models, Molecular; Oligopeptides; Protein Binding; Zinc | 2019 |
Upgrading and Validation of the AMBER Force Field for Histidine and Cysteine Zinc(II)-Binding Residues in Sites with Four Protein Ligands.
Topics: Binding Sites; Cysteine; Histidine; Ligands; Molecular Dynamics Simulation; Protein Conformation; Proteins; Reproducibility of Results; Zinc | 2019 |
A ratiometric fluorescent nanoprobe consisting of ssDNA-templated silver nanoclusters for detection of histidine/cysteine, and the construction of combinatorial logic circuits.
Topics: Animals; Biosensing Techniques; Cattle; Cysteine; DNA, Single-Stranded; Fluorescence; Fluorescent Dyes; Histidine; Logic; Metal Nanoparticles; Microscopy, Electron, Transmission; Particle Size; Silver; Surface Properties | 2019 |
On the interaction of N-heterocyclic carbene Ir
Topics: Cysteine; Heterocyclic Compounds; Histidine; Iridium; Organometallic Compounds; Peptides | 2019 |
Differential effects of variations in human P450 oxidoreductase on the aromatase activity of CYP19A1 polymorphisms R264C and R264H.
Topics: Adrenal Hyperplasia, Congenital; Amino Acid Substitution; Androstenedione; Arginine; Aromatase; Cysteine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Activation; Histidine; Humans; Models, Molecular; Mutation, Missense; Polymorphism, Single Nucleotide; Protein Conformation; Structure-Activity Relationship | 2020 |
Syntheses of Atypically Fluorinated Peptidyl Macrocycles through Sequential Vinylic Substitutions.
Topics: Cysteine; Histidine; Humans; Macrocyclic Compounds; Peptides; Serine; Tyrosine; Vinyl Compounds | 2020 |
Comparison of the pH-dependent formation of His and Cys heptapeptide complexes of nickel(II), copper(II), and zinc(II) as determined by ion mobility-mass spectrometry.
Topics: Cysteine; Histidine; Hydrogen-Ion Concentration; Ion Mobility Spectrometry; Mass Spectrometry; Metals, Heavy; Models, Molecular; Oligopeptides; Protein Binding | 2020 |
Effects of zinc chelating nutrients on Aflatoxin production in Aspergillus flavus.
Topics: Aflatoxin B1; Aspergillus flavus; Chelating Agents; Cysteine; Histidine; Oligopeptides; Zinc | 2020 |
Metabonomics and the Gut Microbiome Associated With Primary Response to Anti-TNF Therapy in Crohn's Disease.
Topics: Adalimumab; Adult; Bile Acids and Salts; Biomarkers, Pharmacological; Crohn Disease; Cysteine; Feces; Female; Histidine; Humans; Inflammation; Infliximab; Lipid Metabolism; London; Longitudinal Studies; Male; Metabolomics; Predictive Value of Tests; RNA, Ribosomal, 16S; Tumor Necrosis Factor Inhibitors | 2020 |
Methods to Study the Structure and Catalytic Activity of cis-Splicing Inteins.
Topics: Aspartic Acid; Biocatalysis; Biochemistry; Carbon Isotopes; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Exteins; Gene Expression; Genetic Vectors; Histidine; Hydrogen-Ion Concentration; Inteins; Maltose-Binding Proteins; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Splicing; Recombinant Fusion Proteins | 2020 |
Protonation of the Cysteine Axial Ligand Investigated in His/Cys
Topics: Cysteine; Cytochrome c Group; Histidine; Ligands; Molecular Structure; Protons; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 2020 |
The 3-His Metal Coordination Site Promotes the Coupling of Oxygen Activation to Cysteine Oxidation in Cysteine Dioxygenase.
Topics: Crystallography, X-Ray; Cysteine; Cysteine Dioxygenase; Ferric Compounds; Histidine; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Oxygen | 2020 |
Structural Insights into the Mechanism of the Radical SAM Carbide Synthase NifB, a Key Nitrogenase Cofactor Maturating Enzyme.
Topics: Archaeal Proteins; Binding Sites; Crystallography, X-Ray; Cysteine; Glutamic Acid; Histidine; Iron-Sulfur Proteins; Methanosarcinales; Models, Chemical; Oxidoreductases; Protein Binding; Protein Conformation; S-Adenosylmethionine | 2020 |
The Biosynthetic Pathway of Ergothioneine in Culinary-Medicinal Winter Mushroom, Flammulina velutipes (Agaricomycetes).
Topics: Agaricales; Antioxidants; Biosynthetic Pathways; Cysteine; Ergothioneine; Escherichia coli; Flammulina; Gene Expression; Histidine; Pyridoxal Phosphate | 2020 |
Use of paramagnetic
Topics: Amino Acid Transport System X-AG; Cryoelectron Microscopy; Cysteine; Fluorine; Histidine; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Nickel; Protein Conformation; Protein Domains; Pyrococcus horikoshii | 2020 |
Efficient refolding of recombinant reteplase expressed in Escherichia coli strains using response surface methodology.
Topics: Arginine; Cysteine; Disulfides; Escherichia coli; Freezing; Glutathione; Histidine; Humans; Inclusion Bodies; Methionine; Protein Denaturation; Protein Refolding; Recombinant Proteins; Tissue Plasminogen Activator | 2020 |
Structural stability of the SARS-CoV-2 main protease: Can metal ions affect function?
Topics: Cobalt; Coronavirus 3C Proteases; Cysteine; Histidine; Protease Inhibitors; Protein Binding; Protein Stability; Protein Unfolding; SARS-CoV-2 | 2020 |
Free-amino acid metabolic profiling of visceral adipose tissue from obese subjects.
Topics: Adipose Tissue; Adult; Aged; Amino Acids; Amino Acids, Branched-Chain; Chromatography, Liquid; Cysteine; Female; Gas Chromatography-Mass Spectrometry; Histidine; Humans; Intra-Abdominal Fat; Male; Metabolome; Metabolomics; Methionine; Middle Aged; Obesity; Tandem Mass Spectrometry; Taurine; Tryptophan; Young Adult | 2020 |
The pH-Induced Selectivity Between Cysteine or Histidine Coordinated Heme in an Artificial α-Helical Metalloprotein.
Topics: Amino Acid Sequence; Catalysis; Cysteine; Electron Spin Resonance Spectroscopy; Heme; Histidine; Hydrogen-Ion Concentration; Iron; Metalloproteins; Oxidation-Reduction; Oxygen; Peptides; Protein Conformation, alpha-Helical | 2021 |
Histidine
Topics: Chlorides; Cysteine; Halogens; Heme; Histidine; Oxidation-Reduction; Peroxidase; Peroxidases | 2021 |
Structure prediction of neutral physiological copper(II) compounds with l-cysteine and l-histidine.
Topics: Coordination Complexes; Copper; Cysteine; Density Functional Theory; Histidine; Models, Chemical; Molecular Conformation | 2021 |
Metabolomic signature of amino acids in plasma of patients with non-segmental Vitiligo.
Topics: Amino Acids; Arginine; Cysteine; Glutamates; Glycine; Histidine; Humans; Lysine; Metabolomics; Ornithine; Proline; Vitiligo | 2021 |
Structural insights into the enhanced thermostability of cysteine substitution mutants of L-histidine decarboxylase from Photobacterium phosphoreum.
Topics: Cysteine; Histidine; Histidine Decarboxylase; Photobacterium | 2022 |
Zn-Induced Interactions Between SARS-CoV-2 orf7a and BST2/Tetherin.
Topics: Antigens, CD; Cysteine; GPI-Linked Proteins; Histidine; Humans; Molecular Dynamics Simulation; Protein Binding; SARS-CoV-2; Viral Proteins; X-Ray Absorption Spectroscopy; Zinc | 2021 |
Characterization of Histidine Functionalization and Its Timing in the Biosynthesis of Ribosomally Synthesized and Posttranslationally Modified Thioamitides.
Topics: Amino Acid Sequence; Cysteine; Histidine; Peptides; Protein Processing, Post-Translational; Protein Sorting Signals | 2022 |
The
Topics: Animals; Arginine; Bacterial Proteins; Cysteine; Cysteine Proteases; Dysentery, Bacillary; Histidine; Mammals; Mechanistic Target of Rapamycin Complex 1; Saccharomyces cerevisiae; Shigella; Shigella flexneri; Type III Secretion Systems | 2022 |
Isolation and characterization of novel antihypertensive bioactive peptides from brassica napus and angiotensin-converting enzyme (ace) inhibition potential.
Topics: Alanine; Angiotensins; Antihypertensive Agents; Arginine; Brassica napus; Cysteine; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptides; Peptidyl-Dipeptidase A; Phenylalanine; Proline; Tandem Mass Spectrometry; Threonine; Tyrosine; Valine | 2022 |
Histidine Ligated Iron-Sulfur Peptides.
Topics: Cysteine; Histidine; Iron; Iron-Sulfur Proteins; Peptides; Sulfur | 2022 |
Tuning reduction potentials of type 1 copper center in azurin by replacing a histidine ligand with its isostructural analogues.
Topics: Azurin; Copper; Cysteine; Electron Spin Resonance Spectroscopy; Histidine; Ligands; Methionine; Pseudomonas aeruginosa | 2022 |
The Nϵ-Rule for Serine, but Not Cysteine Catalytic Triads.
Topics: Binding Sites; Cysteine; Histidine; Imidazoles; Models, Molecular; Protons; Serine | 2022 |
Comparative cisplatin reactivity towards human Zn7-metallothionein-2 and MTF-1 zinc fingers: potential implications in anticancer drug resistance.
Topics: Amino Acid Sequence; Antineoplastic Agents; Chelating Agents; Cisplatin; Coordination Complexes; Cysteine; DNA; DNA-Binding Proteins; Drug Resistance; Histidine; Humans; Metallothionein; Metals; Oligonucleotides; Transcription Factors; Zinc; Zinc Fingers | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
Spectroscopic and QM/MM studies of the Cu(I) binding site of the plant ethylene receptor ETR1.
Topics: Binding Sites; Copper; Cysteine; Ethylenes; Histidine; Receptors, Cell Surface; X-Ray Absorption Spectroscopy | 2022 |
Molecular and functional characterization of zinc finger aspartate-histidine-histidine-cysteine (DHHC)-type containing 1, ZDHHC1 in Chinese perch Siniperca chuatsi.
Topics: Acyltransferases; Animals; Antiviral Agents; Cysteine; DNA Virus Infections; Fish Diseases; Fish Proteins; Histidine; Iridoviridae; Perches; Zinc Fingers | 2022 |
A Single
Topics: Antioxidants; Aspergillus fumigatus; Cysteine; Egtazic Acid; Ergothioneine; Histidine; Humans; Methionine; Saccharomyces cerevisiae; Sulfur | 2022 |
Computational Elucidation of the Solvent-Dependent Addition of 4-Hydroxy-2-nonenal (HNE) to Cysteine and Cysteinate Residues.
Topics: Aldehydes; Amino Acids; Antioxidants; Cysteine; Histidine; Lipid Peroxidation; Lysine; Oxidative Stress; Solvents; Water | 2022 |
MitoNEET's Reactivity of Lys55 toward Pyridoxal Phosphate Demonstrates its Activity as a Transaminase Enzyme.
Topics: Cysteine; Glutamates; Histidine; Hydrogen; Iron; Iron-Sulfur Proteins; Ketoglutaric Acids; Lysine; Mitochondrial Proteins; Pyridoxal Phosphate; Sulfur; Transaminases | 2022 |
Genome-wide identification, new classification, expression analysis and screening of drought & heat resistance related candidates in the RING zinc finger gene family of bread wheat (Triticum aestivum L.).
Topics: Bread; Cysteine; Droughts; Gene Expression Regulation, Plant; Histidine; Phylogeny; Plant Proteins; Stress, Physiological; Transcription Factors; Triticum; Zinc; Zinc Fingers | 2022 |
Single-Nucleotide Polymorphisms, c.415C > T (Arg139Cys) and c.416G > A (Arg139His), in the NUDT15 Gene Are Associated with Thiopurine-Induced Leukopenia.
Topics: Arginine; Cysteine; Histidine; Humans; Leukopenia; Polymorphism, Single Nucleotide; Pyrophosphatases; Retrospective Studies | 2023 |
Dipeptide-Capped Copper Nanoparticles as Chiral Nanozymes for Colorimetric Enantioselective Recognition of 3,4-Dihydroxy-d,l-phenylalanine.
Topics: Colorimetry; Copper; Cysteine; Histidine; Levodopa; Metal Nanoparticles; Peroxidases; Phenylalanine; Stereoisomerism | 2023 |
CH vs. HC-Promiscuous Metal Sponges in Antimicrobial Peptides and Metallophores.
Topics: Antimicrobial Peptides; Copper; Cysteine; Ferrous Compounds; Histidine; Metals; Peptides | 2023 |
Derivatives of the Fungal Natural Product Illudalic Acid Inhibit the Activity of Protein Histidine Phosphatase PHPT1.
Topics: Biological Products; Cysteine; Histidine; Phosphoric Monoester Hydrolases | 2023 |