histidine has been researched along with aspartic acid in 978 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 338 (34.56) | 18.7374 |
| 1990's | 194 (19.84) | 18.2507 |
| 2000's | 322 (32.92) | 29.6817 |
| 2010's | 104 (10.63) | 24.3611 |
| 2020's | 20 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Scozzafava, A; Supuran, CT | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M | 1 |
| Anthony, A; Augustyn, E; Bauer, J; Campbell, J; Chien, HC; Colas, C; Finke, K; Flint, A; Fotiadis, D; Giacomini, KM; Hall, C; Hansen, L; Heeren, N; Hernandez, C; Schlessinger, A; Springer, S; Stoner, L; Thomas, AA; Venteicher, B; Zur, AA | 1 |
| Petz, D; Schneider, F | 1 |
| Kaletha, K; Skladanowski, A; Zydowo, M | 1 |
| Brittain, HG; Richardson, FS | 1 |
| Chrambach, A; Nguyen, NY | 1 |
| Lodge, D | 1 |
| Katze, JR | 2 |
| Chibata, I; Tosa, T | 1 |
| Umbarger, HE | 2 |
| Igarashi, Y; Katsunuma, T; Saheki, T; Takada, S | 1 |
| Powars, D; Schroeder, WA; Shelton, JB; Shelton, JR | 1 |
| Dozy, AM; Kan, YW; Lie-Injo, LE; Lopes, M; Todd, D | 1 |
| Bantzer, P; Jäkel, A; Liappis, N | 1 |
| Hidaka, K; Iuchi, I; Kusumoto, T; Shibata, S; Ueda, S | 1 |
| Charache, S; Clegg, JB | 1 |
| Battistin, L | 1 |
| Bendall, MR; Lowe, G | 1 |
| Fukutome, H; Kitayama, HP | 1 |
| Barbeau, A; Beroniade, V; Breton, G; Geoffroy, G; Lemieux, B; Melançon, S; Shapcott, D | 1 |
| Lowe, NR; Robinson, C; Weatherell, JA | 1 |
| Kehoe, JS | 1 |
| Mak, WW; Milne, AN; Wong, JT | 1 |
| Casey, R; Lang, A | 1 |
| Crain, PF; Harada, F; Kasai, H; Liehr, JG; McCloskey, JA; Nishimura, S; Oashi, Z; Oppenheimer, NJ; von Minden, DL | 1 |
| Katze, JR; Mosteller, RD | 1 |
| Noda, K | 1 |
| Bayer, E; Hemmasi, B | 1 |
| Chellemi, F | 1 |
| Battistin, L; Lorenzi, AD; Varotto, M | 1 |
| Hewitt, JA; Kilmartin, JV; Wootton, JF | 1 |
| Efremov, GD; Huisman, TH; Hunter, E; Niazi, GA; Nikolov, N | 1 |
| Dickerson, JW; Pao, SK | 1 |
| Drysdale, GR; Evans, CT; Kurz, LC; Riley, MC; Srere, PA | 1 |
| Lin, JJ; Sancar, A | 1 |
| Bast, P; Beacham, IR; Derst, C; Harms, E; Jennings, MP; Röhm, KH; Wehner, A | 1 |
| de Aguilera, MC; Osumi-Davis, PA; Woody, AY; Woody, RW | 1 |
| Cleland, WW; O'Leary, MH; Parmentier, LE; Schachman, HK; Turnbull, JL; Waldrop, GL | 1 |
| Chiappinelli, L; Filtri, P; Mancini, V; Pessi, A | 1 |
| Anderson, RJ; Breckon, R; Dillingham, MA; Dixon, BS; Kaehny, MM | 1 |
| Holm, L; Karp, M; Knowles, J; Mäntsälä, P; Meyer, P; Niskanen, J; Ollikka, P; Suominen, I; Vihinen, M | 1 |
| Alter, GM; Casazza, JP; Evans, CT; Nemeth, P; Srere, PA; Zhi, W | 1 |
| Jenster, G; Kaufman, M; Kuiper, GG; Liao, S; Ris-Stalpers, C; Romalo, G; Rosenfield, RL; Sai, T; Trifiro, MA; van Rooij, HC | 1 |
| Cederholm, MT; Doscher, MS; Lee, L; Stuckey, JA | 1 |
| McAlister-Henn, L; Steffan, JS | 1 |
| Frank, BH; Hua, QX; Lynch, CS; Shoelson, SE; Weiss, MA | 1 |
| Schachman, HK; Wente, SR | 1 |
| Bourret, RB; Hess, JF; Simon, MI | 1 |
| Nathans, J | 1 |
| Kubodera, H; Nakagawa, S; Umeyama, H | 1 |
| Cunin, R; Hervé, G; Ladjimi, MM; Van Vliet, F; Xi, XG | 1 |
| Burke, GT; Hu, SQ; Katsoyannis, PG; Ohta, N; Schwartz, GP; Zong, L | 1 |
| Anderson, DE; Becktel, WJ; Dahlquist, FW | 1 |
| Bardet, J; de Blois, MC; Kamoun, P; Lejeune, J; Parvy, P; Peeters, M; Rabier, D; Rethoré, MO | 1 |
| Alicot, EM; Bergamaschini, L; Carroll, MC; Fathallah, DM; Isenman, DE | 1 |
| Cheek, JM; Edmond, J; Jones, MR; Tamaki, J; Wu, PY | 1 |
| Blech, M; Bretschneider, HJ; Kallerhoff, M; Kehrer, G; Langheinrich, M | 1 |
| Bakken, V; Högh, BT; Jensen, HB | 1 |
| Dean, RT; McElligott, MA; Wolff, SP | 1 |
| Harris, GW; Howlin, B; Moss, DS | 1 |
| Kihara, H; Kohzuma, T; Oda, N; Ohno, M | 1 |
| Kumaoka, H; Tazuya, K; Yamada, K | 1 |
| Fairbrother, WJ; Littlechild, JA; Minard, P; Walker, PA; Watson, HC; Williams, RJ | 1 |
| Mei, B; Zalkin, H | 1 |
| Bagert, U; Röhm, KH | 1 |
| Bidigare, RR; Choudhury, RR; Mehta, BJ; Pettigrew, DW; Sander, EG; Scheffler, JE | 1 |
| Farber, JM; Levine, RL | 1 |
| Arrieta, A; Bonilla, E; Prasad, AL | 1 |
| Kleanthous, C; Schachman, HK; Wemmer, DE | 1 |
| Carroll, RJ; Chan, SJ; Hammer, RE; Rubenstein, AH; Steiner, DF; Swift, HH | 1 |
| Cullis, PM; Kleanthous, C; Lewendon, A; Murray, IA; Shaw, WV | 1 |
| Balaram, P; Sahal, D | 1 |
| Craik, CS; Finer-Moore, J; Fletterick, RJ; Hamlin, R; Rutter, WJ; Sprang, S; Standing, T; Stroud, RM; Xuong, NH | 1 |
| Atkinson, T; Barstow, DA; Chia, WN; Clarke, AR; Holbrook, JJ; Wilks, HM | 1 |
| Dreybrodt, W; el Naggar, S; Schweitzer-Stenner, R | 1 |
| Brennan, SO | 1 |
| Karlsson, JO; Sjöstrand, J | 1 |
| Banay-Schwartz, M; Gergely, A; Lajtha, A; Teller, DN | 1 |
| Tener, GM; White, BN | 1 |
| Longton, RW | 1 |
| Qadri, SM; Williams, RP | 1 |
| Hunkapiller, MW; Richards, JH; Smallcombe, SH; Witaker, DR | 1 |
| Hunkapiller, MW; Richards, JH; Smallcombe, SH; Whitaker, DR | 1 |
| Blumauerová, M; Callieri, DA; Cudlín, J; Hostálek, Z; Ismail, AA; Vanĕk, Z | 1 |
| Banerjee, AB; Bhattacharyya, SK | 1 |
| Murali, DK; Radhakrishnan, AN | 1 |
| Cohen, AB | 1 |
| Froncish, W; Kalmanson, AE; Kharitonenkov, IG; Yuferov, VP | 1 |
| Gregerman, RI; Kowatch, MA; Weaver, T | 1 |
| Anfinsen, CB; Cone, JL; Cusumano, CL; Taniuchi, H | 1 |
| Igarashi, K; Takeda, Y; Yo, M | 1 |
| Olszowy, J; Switzer, RL; White, MN | 1 |
| Karadźić, V; Micić, D; Rakić, L | 1 |
| Hamilton, HB; Imai, K; Miyaji, T; Shibata, S | 1 |
| Oda, KI; Sekiya, T | 1 |
| MacLeod, RA; Rogers, HJ; Thurman, P | 1 |
| Mulder, AH; Snyder, SH | 1 |
| White, BN | 1 |
| Casey, JW; Getz, GS; Hsu, HJ; Rabinowitz, M | 1 |
| Burleigh, M; Smith, MJ | 1 |
| Aktin, E; Bergisadi, N; Güven, KC; Koyuncuoglu, H | 1 |
| Bronk, JR; Leese, HJ | 1 |
| Banay-Schwartz, M; Gergely, A; Lajtha, A | 1 |
| Asafov, GB; Ekisenina, NI; Ivanova, LM; Lumel'skiĭ, VIa; Smagin, VG | 1 |
| Lindig, OH; Mitlin, N; Thompson, AC; Wiygul, G | 1 |
| Crossley, AC; Evans, PD | 1 |
| Anandaraj, MP; Cherayil, JD | 1 |
| Klöss, S; Rumrich, G; Ullrich, KJ | 1 |
| Hewitt, JA; Kilmartin, JV | 1 |
| Huestis, WH; Millett, F; Raftery, MA | 1 |
| Castillo, CL; Mayer, A; Ogawa, S; Shulman, RG | 1 |
| Hayes, ML; Hyatt, AT | 1 |
| Harada, F; Nishimura, S | 1 |
| Harada, F; Nishimura, S; Oashi, Z; Saneyoshi, M | 1 |
| Homer, RB | 1 |
| Izui, K; Katsuki, H; Teraoka, H | 1 |
| Sunde, ML | 1 |
| Anthony, C; Drabble, WT; Robinson, JH | 1 |
| Hartley, BS | 1 |
| Doctor, BP; Sodd, MA | 1 |
| Halpern, YS | 1 |
| Pittsyn, OB | 1 |
| Cohen, JS; Heller, SR; Sachs, DH; Schechter, AN; Shrager, RI | 1 |
| Robillard, G; Shulman, RG | 3 |
| Gibson, QH; Hamilton, HB; Nagel, RL; Olson, JS | 1 |
| Lajtha, A; Sershen, H; Seta, K | 1 |
| Coulson, RA; Herbert, JD | 1 |
| Desai, MP; Lehmann, H; Merchant, SM; Sukumaran, PK; Wiltshire, BG | 1 |
| Eccleston, M; Kelly, DP | 1 |
| Bradbury, JH; Ley, KF | 1 |
| Belusko, RJ; Bruce, JI; Ruff, MD; Werner, JK | 1 |
| Morino, Y; Okamoto, M | 1 |
| Negishi, K; Sugawara, K | 1 |
| Gruber, L; Harris, JE | 1 |
| Brockerhoff, H | 1 |
| Galbraith, P; Lehmann, H; Vella, F; Wiltshire, B | 1 |
| Pulsinelli, PD | 1 |
| Boling, JA; Ely, DG; Nishimuta, JF | 1 |
| Puett, D | 1 |
| Bartels, K; Huber, R; Kukla, D; Rühlmann, A; Schwager, P | 1 |
| Bystrov, VF; Chervin, II; Dudkin, SM; Karpeisky, MY; Sacharovsky, VG; Shliapnikov, SV; Yakovlev, GI | 1 |
| Tulinsky, A; Vandlen, RL | 1 |
| Wright, HT | 1 |
| Allen, G; Lowe, G | 1 |
| Herbert, JD | 1 |
| Imamura, A; Nagata, C; Umeyama, H | 1 |
| Alcaraz, AF; Cohen, MB; Masuoka, DT; Spolter, L | 1 |
| Kirschenbaum, DM | 1 |
| Bruun, A; Ehinger, B; Forsberg, A | 1 |
| Bernstein, IA; Gray, RH; Sibrack, LA | 1 |
| Kay, LM; Krieger, M; Stroud, RM | 1 |
| Berry, HK; Brunner, RL; Butcher, RE; Elliot, LA | 1 |
| Bahadur, K; Singh, YP; Verma, ML | 1 |
| Read, CP; Ruff, MD | 1 |
| Chambers, JL; Christoph, GG; Kay, L; Krieger, M; Stroud, RM | 1 |
| Kilejian, A | 1 |
| Atassi, MZ; Rosemblatt, MC | 1 |
| De Luca, F; Macaione, S; Ruggeri, P; Tucci, G | 1 |
| Lajtha, A; Sershen, H | 1 |
| Bamford, DR; Donnelly, H | 1 |
| Chow, RB; Kassel, B | 1 |
| Freeman, HC | 1 |
| Iwashima, A; Kawasaki, T; Nakamura, M; Nose, Y | 1 |
| Tristram, H | 1 |
| Berger, H; Yanofsky, C | 1 |
| Sekiya, T; Ukita, T | 1 |
| Borek, E; Hay, J; Pillinger, DJ | 1 |
| Christomanos, AA; Dimitriades, A | 1 |
| Martin, RG; Rothman-Denes, L | 1 |
| Kotyk, A; Ponec, M; Ríhová, L | 1 |
| Aubert, JP; Millet, J; Schaeffer, P | 1 |
| Kinoshita, Y; Nemoto, G; Ujiie, A | 1 |
| Bourrillon, R; Jouanneau, J; Razafimahaleo, E | 1 |
| Vinnars, E | 2 |
| Roxby, R; Tanford, C | 1 |
| Boling, JA; Bradley, NW; Willard, JC | 1 |
| Cheng, S; Martinez-Carrion, M | 1 |
| Aikawa, T; Ishikawa, E; Matsutaka, H; Takezawa, K | 1 |
| Polgár, L | 1 |
| Morishita, S; Muramatsu, K; Odagiri, H; Takeuchi, H | 1 |
| Franzblau, C; Hollander, W; Kramsch, DM | 1 |
| Campbell, DJ; Reid, DW; Yakymyshyn, LY | 1 |
| Galiazzo, G; Gennari, G; Jori, G; Scoffone, E | 1 |
| Allewell, NM; Wyckoff, HW | 1 |
| Gross, W; Ring, K | 1 |
| Barkin, E; Levy, HL | 1 |
| Hunter, DR; Segel, IH | 1 |
| Shearer, TR; Suttie, JW | 1 |
| Kim, S; Paik, WK | 1 |
| Imm, B; Lamar, C | 1 |
| Hornig, D; Weber, F; Wiss, O | 1 |
| Markelova, SI; Zharikova, GG | 3 |
| Ortwerth, BJ | 1 |
| Bhalla, VK; Robertson, RT; Williams, WL | 1 |
| Ermol'eva, ZV; Kolosova, IV; Pasternak, NA; Pokidova, NV; Shenderovich, VA | 1 |
| Gibbons, RJ; Loesche, WJ | 1 |
| Kotelchuck, D; Scheraga, HA | 1 |
| Hellman, A; Hellman, KB; Martin, DH; Novelli, GD; Yang, WK | 1 |
| Geisler, C; Höcker, P; Stacher, A; Wiser, M | 1 |
| English, LS; Les, DN; Rogers, LJ | 1 |
| Appella, E; Martin, RG; Voll, MJ | 1 |
| Perutz, MF | 1 |
| Caston, JD; Singer, M | 2 |
| Abeles, RH; Givot, IL; Smith, TA | 1 |
| Kapoor, IJ; Tandon, RN | 1 |
| Blow, DM; Henderson, R; Steitz, TA | 1 |
| Irie, M; Tomita, M; Ukita, T | 1 |
| Ermol'eva, ZV; Pokidova, NV; Zhuravleva, TP | 1 |
| Battistin, L; Grynbaum, A; Lajtha, A | 2 |
| Hatano, M; Obara, Y; Ono, S | 1 |
| D'Mello, JP; Lewis, D | 1 |
| Ermol'eva, ZV; Evseenko, LK; Iulikova, EP; Kolosova, IV; Pasternak, NA; Pokidova, NV; Shenderovich, VA; Silaev, AB | 1 |
| Grimble, RF; Whitehead, RG | 1 |
| Charlesworth, D; Eng, LI; Lehmann, H; Lorkin, PA; Rahbar, S; Tuchinda, S | 1 |
| Lajtha, A; Sadasivudu, B | 1 |
| Neuhoff, V; Weise, M | 1 |
| Chen, C; Horecker, BL; Lai, CY | 1 |
| Fürst, P; Josephson, B; Vinnars, E | 1 |
| Baranova, IP; Egorov, NS | 1 |
| Eng, AC; Merry, CC; Vella, F | 1 |
| Jones, JD; Ulrich, JA; Winkelmann, RK | 1 |
| Cohen, LH; Gotchel, BV | 1 |
| Hong, BS; Tu, AT | 1 |
| Balasubramanian, M; Myers, RF | 1 |
| Baños, G; Daniel, PM; Love, ER; Moorhouse, SR; Pratt, OE | 1 |
| Graham, JD; Mottram, DR | 1 |
| Flory, B; Krassner, SM | 1 |
| Debusk, AG; Wolfinbarger, L | 1 |
| Kickuth, R; Scheffer, F; Schlimme, E | 1 |
| Carrell, RW; Lehmann, H; Pribilla, W | 1 |
| Gusev, EI | 1 |
| Ansorge, S; Bohley, P | 1 |
| Demeyer, DI; Henderickx, HK | 1 |
| Nakahara, M; Yamada, S | 1 |
| Gallo, E; Lehmann, H; Tangheroni, W; Zorcolo, G | 2 |
| Coulter, JR; Hann, CS | 1 |
| Egorov, NS; Mikhailova, TN; Toropiova, EG | 1 |
| Barnard, EA; Glick, DM; Goren, HJ | 1 |
| Jardetzky, O; Markley, JL; Putter, I | 1 |
| Brown, HH | 1 |
| Steenbergen, ST; Weinberg, ED | 1 |
| Aoki, M; Aonuma, S; Hama, T; Tamaki, N | 1 |
| Atarova, GT; Olenicheva, LS | 1 |
| Bonner, J; DeLange, RJ; Fambrough, DM; Smith, EL | 1 |
| Adams, HR; Boyd, EM; Huisman, TH; Miller, A; Wilson, JB | 1 |
| Imai, K | 1 |
| Elkan, GH; Kwik, I | 1 |
| Indada, Y; Matsushima, A; Nomoto, M; Sakurai, K; Shibata, K | 1 |
| Iversen, LL; Neal, MJ | 1 |
| Howard, PN; Sutton, HE; Wang, AC | 1 |
| Hogan, JP; Lindsay, JR; Weston, RH | 1 |
| Deer, A; Kocy, O; Ondetti, MA; Pluscec, J; Sheehan, JT | 1 |
| Ershova, EB | 1 |
| Samofalova, MS | 1 |
| Blow, DM; Henderson, R; Matthews, BW; Sigler, PB | 1 |
| Birktoft, JJ; Blow, DM; Hartley, BS | 1 |
| Finn, GR; Galaev, IuV; Loktionov, AM | 1 |
| Beisel, WR; Dangerfield, HG; Feigin, RD | 1 |
| Gross, S; Maskaleris, ML; Milhorat, AT | 1 |
| Johnson, MS; Young, RJ | 1 |
| Menden, E; Vangala, RR | 1 |
| Gineitis, AA; Vinogradova, IA; Vorobyev, VI | 1 |
| Rüterjans, H; Witzel, H | 1 |
| Burns, MJ; Faust, RG | 1 |
| Costa, C; Salvatore, F; Zappia, V | 1 |
| Guzzo, AV | 1 |
| Neame, KD | 1 |
| Dennis, ES; Goodchild, CG | 1 |
| Pengra, RM; Yoch, DC | 1 |
| Squibb, RL | 5 |
| Munier, RL; Sarrazin, G | 1 |
| Gurley, LR; Kischer, CW; Shepherd, GR | 1 |
| Kuz'mina, VV | 1 |
| Carver, MJ; Ryan, WL | 1 |
| Estes, FL; Wetzel, RL | 1 |
| Harper, E; Scharrer, B; Seifter, S | 1 |
| Oliver, IT; Yeung, D | 1 |
| Hubbard, JS; Stadtman, ER | 1 |
| Burns, VW | 1 |
| Brimhall, B; Jones, RT; Koler, RD; Osgood, EE | 1 |
| Abasov, IT | 1 |
| Agnihotri, VP; Vaartaja, O | 1 |
| Lerner, J; Taylor, MW | 1 |
| Kuroda, Y | 1 |
| Hirono, S; Nakagawa, S; Umeyama, H | 1 |
| Van Etten, RL | 1 |
| Fujita, S; Kobayashi, Y; Ohta, Y; Saito, S | 1 |
| Miller, AM; Schwartz, EA | 1 |
| Bedendo, B; Bellinello, F; Bernardi, F; Cappellozza, G; Conconi, F; Cristofori, G; del Senno, L; Marchetti, G; Mercuriati, M; Perrotta, C; Salsini, G; Vullo, C | 1 |
| Nakagawa, S; Umeyama, H | 1 |
| Campagnari, F; Carroll, MJ; Clerici, L; Merlini, M; Vercellini, L | 1 |
| Heaton, FW; Seal, CJ | 1 |
| Halász, P; Polgár, L | 1 |
| Murray, RG; Whitby, GE | 1 |
| Hamaguchi, K; Kuramitsu, S | 1 |
| Farkas, WR | 1 |
| Kubli, E; Schmidt, T | 1 |
| Wold, F | 1 |
| Kudo, T; Nakagawa, S; Umeyama, H | 1 |
| Genest, M; Ptak, M | 1 |
| Trudelle, Y | 1 |
| Banaszak, LJ; Birktoft, JJ | 1 |
| Caughey, WS; Charache, S; Lanir, A | 1 |
| Heard, JT; Steiner, BM; Tritz, GJ | 1 |
| Jordan, F; Polgár, L | 1 |
| Kossiakoff, AA; Spencer, SA | 1 |
| de Haas, GH; Dijkman, R; Donné-Op den Kelder, GM; Egmond, MR; Hille, JD | 1 |
| Cui, K; Lu, AY; Ma, Q; Yang, CS | 1 |
| Castagnola, M; Corda, M; Giardina, B; Manca, L; Masala, B; Olianas, A; Pellegrini, M; Sanna, MT; Scatena, R | 1 |
| Allende, L; Alvarez, M; Arnaiz-Villena, A; Corell, A; Madroño, A; Paz-Artal, E; Rosal, M; Varela, P | 1 |
| Brennan, TV; Clarke, S | 1 |
| Berner, B; Sznitowska, M | 1 |
| Kim, S; Narayana, SV; Volanakis, JE | 1 |
| Gerchman, Y; Olami, Y; Padan, E; Rimon, A; Schuldiner, S | 1 |
| Herrler, G; Klenk, HD; Pleschka, S | 1 |
| Cai, Y; Ewan, RC; Zimmerman, DR | 1 |
| Frey, PA; Tobin, JB; Whitt, SA | 1 |
| Bjørnholm, B; Dunford, HB; Welinder, KG | 1 |
| Dupureur, CM; Kumar, A; Ramakrishnan, B; Sekharudu, C; Sundaralingam, M; Tsai, MD; Zhu, H | 1 |
| Beetham, JK; Borhan, B; Grant, DF; Hammock, BD; Jones, AD; Landt, S; Parker, AG; Pinot, F | 1 |
| Frey, PA | 1 |
| Chu, HA; Debus, RJ; Nguyen, AP | 2 |
| Bertoli, E; Krzewski, K; Lipińska, B; Skórko-Glonek, J; Tanfani, F | 1 |
| Egle, C; Katunin, V; Kreutzer, R; Ribeiro, S; Rodnina, M; Sprinzl, M; Wagner, A; Wintermeyer, W; Zeidler, W | 1 |
| Cassidy, CS; Frey, PA; Tobin, JB; Whitt, SA | 1 |
| Offer, G; Sessions, R | 1 |
| Fiorillo, MT; Greco, G; Sorrentino, R | 1 |
| Benedetti, M; Ponte, E; Tamburrini, LR | 1 |
| Esaki, N; Kurihara, T; Liu, JQ; Soda, K | 1 |
| Baykov, AA; Cooperman, BS; Goldman, A; Lahti, R; Magretova, NN; Velichko, IS; Velichko, IV; Volk, SE | 1 |
| Alex, LA; Simon, MI; Swanson, RV | 1 |
| Baumeister, W; Lupas, A; Seemüller, E; Zühl, F; Zwickl, P | 1 |
| Haser, R; Kadziola, A; Svensson, B; Søgaard, M | 1 |
| Bertalan, C; Farkas, E; Kowalik-Jankowska, T; Kozlowski, H; Lebkiri, A; Sóvágó, I | 1 |
| Warwicker, J | 1 |
| Frimpong, K; Rodwell, VW | 1 |
| Jakobs, C; Majewski, C; Trebst, A; Uhrig, J | 1 |
| Aiach, M; Aillaud, MF; Alhenc-Gelas, M; Duchemin, J; Emmerich, J; Gandrille, S; Gaussem, P | 1 |
| Dobrowolska, G; Krebs, EG; Li, D; Lozeman, FJ; Marin, O; Meggio, F; Pinna, LA | 1 |
| Li, Y; Man, WJ; O'Connor, CD; Wilton, DC | 1 |
| Banci, L; Bertini, I; Ferrer, JC; Mauk, AG; Morris, IK; Smith, KM; Smith, M; Turano, P | 1 |
| Anderson, RC; Brown, NF; Caplan, SL; Foster, DW; McGarry, JD | 1 |
| Besson, M; Cambau, E; Grosset, J; Jarlier, V; Sougakoff, W; Truffot-Pernot, C | 1 |
| Alam, SL; Erman, JE; Mauro, JM; Poulos, TL; Satterlee, JD | 1 |
| Cox, S; Taylor, SS | 1 |
| Endo, F; Hoshide, R; Ishikawa, K; Kato, I; Kiwaki, K; Koike, E; Komaki, S; Matsuura, T; Oyanagi, K; Suzuki, Y | 1 |
| Berti, PJ; Storer, AC | 1 |
| Fukayama, M; Hirooka, Y; Ishizuki, Y; Mitsuma, T; Naruse, M; Nogimori, T; Sakai, J | 1 |
| Bernard, AM; David, F; Marguet, D; Pierres, M | 1 |
| Haruki, M; Itaya, M; Kanaya, S; Liu, YY; Nakai, C; Noguchi, E; Oobatake, M | 1 |
| Mulrooney, SB; Williams, CH | 1 |
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| Aguilar-Pineda, JA; Barazorda-Ccahuana, HL; Gómez, B; Paredes-Rosan, CA; Valencia, DE | 1 |
| Chen, P; Hu, L; Li, Y; Wang, H; Wang, J; Weng, Y; Xie, C; Zhang, H; Zhang, J | 1 |
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| Hervø-Hansen, S; Højgaard, C; Johansson, KE; Lindorff-Larsen, K; Messens, J; Teilum, K; Wahni, K; Wang, Y; Winther, JR; Young, D | 1 |
| Candy Chen, HJ; Hu, SX; Wu, DC; Yang, TC | 1 |
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| Bowen, D; Chenchen, D; Danni, W; Feng, S; Jie, LI; Min, Z; Ning, K; Qiang, LI; Qianlei, XU; Qingyan, Z; Shoupei, L; Zhen, L; Zhibin, L | 1 |
| Balogh, BD; Csire, G; Erdei, JZ; Király, JM; Kocsi, J; Pinkóczy, J; Székely, E; Várnagy, K | 1 |
| Chen, KH; Kots, E; Lü, W; Mihaljević, L; Osei-Owusu, J; Qiu, Z; Ruan, Z; Tamhaney, A; Weinstein, H; Ye, X | 1 |
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| Bhattacharya, N; Chakrabarty, D; Kolvekar, N; Mondal, S; Sarkar, A | 1 |
| Carpin, S; Chefdor, F; Depierreux, C; Héricourt, F; Lafite, P; Lamblin, F; Larcher, M; Maeda, T; Makhokh, H; Tanigawa, M | 1 |
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41 review(s) available for histidine and aspartic acid
| Article | Year |
|---|---|
Transformations of organic compounds by immobilized microbial cells.
Topics: Arginine; Aspartic Acid; Bacteria; Citrulline; Enzymes, Immobilized; Fumarates; Fungi; Histidine; Malates; Microbiological Techniques; Penicillanic Acid; Penicillins; Species Specificity; Stereoisomerism; Urocanic Acid | 1977 |
Amino acid biosynthesis and its regulation.
Topics: Amino Acids; Arginine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Histidine; Phenylalanine; Pyruvates; Serine; Tyrosine | 1978 |
Utilization of D- and DL- amino acids and analogs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Histidine; Isomerism; Keto Acids; Leucine; Methionine; Nutritional Requirements; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1972 |
The active centers of serine proteinases.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Cattle; Chymotrypsin; Chymotrypsinogen; Endopeptidases; Histidine; Hydrogen-Ion Concentration; Kinetics; Protein Binding; Protein Conformation; Serine; Solubility; X-Ray Diffraction | 1974 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Invariant features of globin primary structure and coding of their secondary structure.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Globins; Glycine; Hemoglobins; Histidine; Myoglobin; Proline; Protein Conformation; Serine; Species Specificity; Threonine; Tyrosine | 1974 |
Crystal structures of metal-peptide complexes.
Topics: Alanine; Aminobutyrates; Aspartic Acid; Binding Sites; Biureas; Cadmium; Chelating Agents; Computers; Copper; Crystallography; Dipeptides; Glutamates; Glycine; Histidine; Imidazoles; Mercury; Metals; Models, Chemical; Nickel; Penicillamine; Peptides; Proline; Silver; Stereoisomerism; Water; Zinc | 1967 |
Control of amino acid biosynthesis in microorganisms.
Topics: Amino Acids; Aspartic Acid; Chromosome Mapping; Enzyme Repression; Escherichia coli; Genetics, Microbial; Histidine; Phenylalanine; Salmonella typhimurium; Tryptophan; Tyrosine | 1968 |
Regulation of amino acid metabolism.
Topics: Amino Acids; Aspartic Acid; Bacteria; Enzyme Repression; Enzymes; Glutamates; Histidine; Models, Biological; Molecular Biology; Phenylalanine; Pyruvates; Serine; Tryptophan; Tyrosine | 1969 |
[Multiplicity and specificity in code recognition of tRNA against specific amino acid].
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography; Cystine; Escherichia coli; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Leucine; Liver; Lysine; Phenylalanine; Rabbits; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Threonine; Tyrosine; Yeasts | 1969 |
Current problems in mechanistic studies of serine and cysteine proteinases.
Topics: Aspartic Acid; Binding Sites; Catalysis; Cysteine; Cysteine Endopeptidases; Endopeptidases; Histidine; Models, Chemical; Papain; Protein Conformation; Serine Endopeptidases | 1982 |
In vivo chemical modification of proteins (post-translational modification).
Topics: Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Glutamates; Glutamine; Histidine; Hydroxylysine; Lysine; Phenylalanine; Proline; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Serine; Threonine; Tryptophan; Tyrosine | 1981 |
Histidine and aspartate phosphorylation: two-component systems and the limits of homology.
Topics: Animals; Aspartic Acid; Histidine; Phosphorylation; Sequence Homology, Amino Acid; Signal Transduction | 1994 |
Signal transduction via the multi-step phosphorelay: not necessarily a road less traveled.
Topics: Animals; Aspartic Acid; Histidine; Histidine Kinase; Phosphorylation; Protein Kinases; Saccharomyces cerevisiae; Signal Transduction; Water-Electrolyte Balance | 1996 |
A review of phylogenetic and metabolic relationships between the acylamino acids, N-acetyl-L-aspartic acid and N-acetyl-L-histidine, in the vertebrate nervous system.
Topics: Animals; Aspartic Acid; Histidine; Nervous System; Phylogeny; Vertebrates | 1997 |
Signal transduction via the histidyl-aspartyl phosphorelay.
Topics: Aspartic Acid; Bacterial Outer Membrane Proteins; Escherichia coli Proteins; Histidine; Histidine Kinase; Multienzyme Complexes; Osmosis; Phosphotransferases; Protein Kinases; Saccharomyces cerevisiae; Signal Transduction | 1997 |
Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold.
Topics: Aspartic Acid; Binding Sites; Chymotrypsin; Histidine; Lysine; Protein Conformation; Serine; Serine Endopeptidases; Structure-Activity Relationship; Substrate Specificity; Trypsin | 1997 |
Canavan disease. Analysis of the nature of the metabolic lesions responsible for development of the observed clinical symptoms.
Topics: Amidohydrolases; Animals; Aspartic Acid; Canavan Disease; Central Nervous System; Female; Fetal Diseases; Histidine; Humans; Pregnancy | 1997 |
His-Asp phosphotransfer signal transduction.
Topics: Adenosine Triphosphate; Aspartic Acid; Histidine; Signal Transduction | 1998 |
Genetics of hemochromatosis.
Topics: Amino Acid Substitution; Aspartic Acid; Cloning, Molecular; Cysteine; Genes, MHC Class I; Genes, Recessive; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Iron; Membrane Proteins; Mutation, Missense; Tyrosine | 1999 |
[His-Asp phosphotransfer signal transduction].
Topics: Aspartic Acid; Bacterial Outer Membrane Proteins; Bacterial Proteins; Escherichia coli Proteins; Histidine; Histidine Kinase; Multienzyme Complexes; Phosphoenolpyruvate Sugar Phosphotransferase System; Protein Kinases; Protein Structure, Tertiary; Signal Transduction; Trans-Activators | 1999 |
His-Asp phosphorelay signaling: a communication avenue between plants and their environment.
Topics: Aspartic Acid; Cytokines; Ethylenes; Histidine; Phosphorylation; Plants; Signal Transduction | 2000 |
Eukaryotic signal transduction via histidine-aspartate phosphorelay.
Topics: Animals; Aspartic Acid; Dictyostelium; Eukaryotic Cells; Histidine; Humans; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Signal Transduction | 2000 |
Synthetic analogs of zinc enzymes.
Topics: Alcohol Dehydrogenase; Amidohydrolases; Amino Acid Motifs; Aminopeptidases; Animals; Aspartic Acid; Bacterial Proteins; Bicarbonates; Binding Sites; Carbonic Anhydrases; Carboxypeptidases; Catalysis; Cations, Divalent; Cysteine; Dihydroorotase; DNA Repair; Enzymes; Escherichia coli Proteins; Glutamic Acid; Histidine; Ligands; Liver; Matrix Metalloproteinases; Metalloproteins; Models, Chemical; Molecular Structure; N-Acetylmuramoyl-L-alanine Amidase; Nitrates; O(6)-Methylguanine-DNA Methyltransferase; Porphobilinogen Synthase; Spectrum Analysis; Thermolysin; Transcription Factors; Water; Zinc | 2001 |
Plant two-component signaling systems and the role of response regulators.
Topics: Arabidopsis Proteins; Aspartic Acid; DNA-Binding Proteins; Histidine; Histidine Kinase; Models, Biological; Phosphorylation; Phosphotransferases; Plant Proteins; Plants; Protein Kinases; Receptors, Cell Surface; Signal Transduction; Transcription Factors | 2002 |
Skin colour and skin cancer - MC1R, the genetic link.
Topics: Alleles; Amino Acid Sequence; Arginine; Aspartic Acid; Base Sequence; Case-Control Studies; Cystine; Genotype; Histidine; Humans; Models, Genetic; Molecular Sequence Data; Phenotype; Polymorphism, Genetic; Receptors, Corticotropin; Receptors, Melanocortin; Signal Transduction; Skin Neoplasms; Skin Pigmentation; Tryptophan; Twins; Twins, Dizygotic; Twins, Monozygotic; Ultraviolet Rays | 2002 |
His-Asp phosphorelay signal transduction in higher plants: receptors and response regulators for cytokinin signaling in Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Bacterial Proteins; Cytokinins; DNA-Binding Proteins; Ethylenes; Histidine; Light; Osmosis; Signal Transduction; Transcription Factors; Virulence Factors | 2002 |
[Communication mechanisms of nitrogen signal transduction in plants].
Topics: Alkyl and Aryl Transferases; Aspartic Acid; Cytokinins; Gene Expression Regulation, Plant; Histidine; Ions; Nitric Acid; Nitrogen; Plant Development; Plant Physiological Phenomena; Plants; Signal Transduction | 2003 |
Plant response regulators implicated in signal transduction and circadian rhythm.
Topics: Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Circadian Rhythm; Cytokinins; Histidine; Light; Signal Transduction | 2004 |
[Iron storage disease].
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Chromosomes, Human, Pair 6; Cysteine; Diabetes Mellitus; Diagnosis, Differential; Hemochromatosis; Histidine; Humans; Hyperpigmentation; Iron Overload; Liver Cirrhosis; Liver Neoplasms; Mass Screening; Phlebotomy; Point Mutation; Population Surveillance; Prevalence; Prognosis; Tyrosine | 2004 |
The roles of the essential Asp-48 and highly conserved His-43 elucidated by the pH dependence of the pseudouridine synthase TruB.
Topics: Aspartic Acid; Base Pairing; Binding Sites; Catalysis; Escherichia coli; Escherichia coli Proteins; Genetic Variation; Histidine; Hydrogen-Ion Concentration; Intramolecular Lyases; Intramolecular Transferases; Kinetics; Models, Molecular; Models, Structural; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Conformation; Protein Structure, Secondary; Substrate Specificity; Tyrosine; Uridine | 2005 |
[Regulation of eukaryotic His-Asp phosphorelay system by proteasome-dependent pathway].
Topics: Aspartic Acid; Bacterial Outer Membrane Proteins; Bacterial Proteins; Escherichia coli Proteins; Eukaryotic Cells; Histidine; Multienzyme Complexes; Osmolar Concentration; Phosphorylation; Plants; Proteasome Endopeptidase Complex; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Trans-Activators; Ubiquitin | 2004 |
Two-component phosphorelay signal transduction systems in plants: from hormone responses to circadian rhythms.
Topics: Arabidopsis; Aspartic Acid; Cell Nucleus; Circadian Rhythm; Cytokinins; Cytoplasm; Histidine; Phosphates; Plant Growth Regulators; Plant Physiological Phenomena; Signal Transduction | 2005 |
Amino acid catabolic pathways of lactic acid bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Aromatic; Amino Acids, Branched-Chain; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Biodegradation, Environmental; Fermentation; Food Microbiology; Glutamate Decarboxylase; Glutamic Acid; Glutamine; Histidine; Lactic Acid; Lactobacillus; Proline | 2006 |
Dual regulation with Ser/Thr kinase cascade and a His/Asp TCS in Myxococcus xanthus.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Base Sequence; DNA, Bacterial; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Developmental; Genes, Bacterial; Histidine; Models, Biological; Molecular Sequence Data; Myxococcus xanthus; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; Transcription Factors | 2008 |
Unconventional serine proteases: variations on the catalytic Ser/His/Asp triad configuration.
Topics: Aspartic Acid; Catalytic Domain; Histidine; Serine; Serine Endopeptidases; Structure-Activity Relationship | 2008 |
Insights on membrane topology and structure/function of UDP-glucuronosyltransferases.
Topics: Animals; Aspartic Acid; Catalytic Domain; Endoplasmic Reticulum; Glucuronosyltransferase; Histidine; Membranes; Protein Conformation; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Substrate Specificity; Uridine Diphosphate; Xenobiotics | 2010 |
Roles of the His-Asp phosphorelay signal transduction system in controlling cell growth and development in Aspergillus nidulans.
Topics: Aspartic Acid; Aspergillus nidulans; Cell Proliferation; Histidine; Phosphorylation; Signal Transduction | 2011 |
Organization and mode of action of two component system signaling circuits from the various kingdoms of life.
Topics: Aspartic Acid; Ecosystem; Eukaryotic Cells; Histidine; Prokaryotic Cells; Signal Transduction | 2016 |
The yeasts phosphorelay systems: a comparative view.
Topics: Aspartic Acid; Candida albicans; Cryptococcus neoformans; Fungal Proteins; Histidine; Histidine Kinase; Kluyveromyces; Phosphates; Phosphorylation; Phosphotransferases; Saccharomyces cerevisiae; Schizosaccharomyces; Signal Transduction; Yeasts | 2017 |
Evaluating the role of trypsin in silk degumming: An in silico approach.
Topics: Aspartic Acid; Histidine; Molecular Docking Simulation; Peptide Hydrolases; Sericins; Serine; Silk; Trypsin | 2022 |
1 trial(s) available for histidine and aspartic acid
| Article | Year |
|---|---|
Serum levels of excitatory amino acids, serine, glycine, histidine, threonine, taurine, alanine and arginine in treatment-resistant depression: modulation by treatment with antidepressants and prediction of clinical responsivity.
Topics: Adult; Aged; Alanine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arginine; Asparagine; Aspartic Acid; Depressive Disorder, Major; Drug Resistance; Drug Therapy, Combination; Excitatory Amino Acids; Female; Fluoxetine; Glycine; Histidine; Humans; Male; Middle Aged; Personality Inventory; Pindolol; Prognosis; Selective Serotonin Reuptake Inhibitors; Serine; Taurine; Threonine; Trazodone; Treatment Outcome | 1998 |
936 other study(ies) available for histidine and aspartic acid
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Carbonic anhydrase activators: human isozyme II is strongly activated by oligopeptides incorporating the carboxyterminal sequence of the bicarbonate anion exchanger AE1.
Topics: Anion Exchange Protein 1, Erythrocyte; Binding Sites; Carbonic Anhydrases; Enzyme Activation; Enzyme Activators; Humans; Isoenzymes; Models, Molecular; Oligopeptides | 2002 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1).
Topics: Amino Acid Transport Systems; Antiporters; Escherichia coli Proteins; HEK293 Cells; Humans; Large Neutral Amino Acid-Transporter 1; Ligands; Molecular Docking Simulation; Phenylalanine; Stereoisomerism; Structural Homology, Protein; Structure-Activity Relationship; Substrate Specificity | 2018 |
Catalytic properties of peptides with hydrolytic activity.
Topics: Aspartic Acid; Binding Sites; Catalysis; Cysteine; Esterases; Histidine; Hydrogen-Ion Concentration; Isoelectric Point; Oligopeptides; Sulfhydryl Compounds; Temperature | 1976 |
Inhibition by alanine of AMP-deaminase from rabbit skeletal muscle.
Topics: Alanine; Allosteric Regulation; AMP Deaminase; Animals; Aspartic Acid; Glutamates; Histidine; Hydrogen-Ion Concentration; Kinetics; Muscles; Nucleotide Deaminases; Rabbits; Structure-Activity Relationship | 1976 |
Circularly polarized emission studies on Tb3+ and Eu3+ complexes with potentially terdentate amino acids in aqueous solution.
Topics: Amino Acids; Aspartic Acid; Binding Sites; Circular Dichroism; Europium; Histidine; Hydrogen-Ion Concentration; Serine; Terbium; Threonine | 1977 |
Stabilization of pH gradients in buffer electrofocusing on polyacrylamide gel.
Topics: Acrylamides; Aspartic Acid; Buffers; Drug Stability; Histidine; Hydrogen-Ion Concentration; Isoelectric Focusing; Serum Albumin, Bovine | 1977 |
L-histidine: effects on sensitivity of cat spinal neurones to amino acids.
Topics: Amino Acids; Amino Acids, Diamino; Animals; Aspartic Acid; beta-Alanine; Cats; Drug Interactions; gamma-Aminobutyric Acid; Glutamates; Histidine; Kainic Acid; Muscimol; Spinal Cord | 1979 |
Alterations in SVT2 cell transfer RNAs in response to cell density and serum type.
Topics: Animals; Asparagine; Aspartic Acid; Cattle; Cell Line; Cell Transformation, Neoplastic; Culture Media; Cyanogen Bromide; Histidine; Mice; Mice, Inbred BALB C; RNA, Transfer; RNA, Viral; Simian virus 40; Tyrosine | 1975 |
Relation of cell type and cell density in tissue culture to the isoaccepting spectra of the nucleoside Q containing tRNAs: tRNATyr, tRNAHis, tRNAAsn and tRNAAsp.
Topics: Asparagine; Aspartic Acid; Cell Line; Cell Transformation, Neoplastic; Contact Inhibition; Cyanogen Bromide; Guanosine; Histidine; RNA, Transfer; Simian virus 40; Tyrosine | 1978 |
Studies on rat liver argininosuccinate synthetase. Inhibition by various amino acids.
Topics: Amino Acids; Animals; Argininosuccinate Lyase; Aspartic Acid; Circular Dichroism; Citrulline; Histidine; Kinetics; Liver; Lyases; Protein Conformation; Rats; Structure-Activity Relationship | 1979 |
Hemoglobin Sunshine Seth - alpha 2 (94 (G1) Asp replaced by His) beta 2.
Topics: Amino Acids; Aspartic Acid; Child, Preschool; Female; Fetal Blood; Globins; Hematologic Tests; Hemoglobins, Abnormal; Histidine; Humans; Infant; Infant, Newborn; Male; Peptide Fragments; Pregnancy | 1979 |
The alpha-globin gene adjacent to the gene for HbQ-alpha 74 Asp replaced by His is deleted, but not that adjacent to the gene for HbG-alpha 30 Glu replaced by Gln; three-fourths of the alpha-globin genes are deleted in HbQ-alpha-thalassemia.
Topics: Aspartic Acid; Chemical Phenomena; Chemistry; Chromosome Deletion; DNA; Genetic Carrier Screening; Globins; Glutamates; Glutamine; Hemoglobin H; Hemoglobins, Abnormal; Histidine; Humans; Hybridization, Genetic; Peptides; Thalassemia | 1979 |
[Normal range of free amino acids in cerebrospinal fluid of children (author's transl)].
Topics: Adolescent; Age Factors; Amino Acids; Aspartic Acid; Child; Child, Preschool; Citrulline; Female; Histidine; Humans; Infant; Lysine; Male; Methods; Serine; Sex Factors; Threonine; Tyrosine | 1977 |
Hemoglobin G Taichung (alpha 74 aspartic acid replaced by histidine) heterozygotes found in two Japanese families.
Topics: Aged; Aspartic Acid; Hemoglobins, Abnormal; Heterozygote; Histidine; Humans; Japan; Male; Middle Aged | 1978 |
The structure of hemoglobin Hopkins-2.
Topics: Aspartic Acid; Female; Hemoglobins, Abnormal; Histidine; Humans; Male; Maryland | 1978 |
Cerebral permeability phenomena in epilepsy.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cell Membrane Permeability; Disease Models, Animal; Extracellular Space; Histidine; Methionine; Mice; Pentylenetetrazole; Rabbits; Seizures | 1976 |
Co-operative ionisation of aspartic-acid-158 and histidine-159 in papain. Evidence from 19F nuclear-magnetic-resonance and fluorescence spectroscopy.
Topics: Aspartic Acid; Chemical Phenomena; Chemistry; Fluorine; Histidine; Hydrolysis; In Vitro Techniques; Ions; Kinetics; Magnetic Resonance Spectroscopy; Papain; Spectrometry, Fluorescence; Sulfhydryl Compounds | 1976 |
A molecular orbital theoretical study on the acid-base property and reactivity of the charge relay system in alpha chymotrypsin.
Topics: Aspartic Acid; Chymotrypsin; Electric Conductivity; Energy Transfer; Histidine; Hydrogen Bonding; Imidazoles; Models, Chemical; Quantum Theory; Thermodynamics | 1976 |
Amino acid metabolism in Friedreich's ataxia.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Friedreich Ataxia; Glycine; Histidine; Humans; Isoleucine; Ornithine; Phenylalanine; Phosphatidylethanolamines; Sarcosine; Serine; Taurine; Tyrosine; Valine | 1976 |
Amino acid composition, distribution and origin of "tuft" protein in human and bovine dental enamel.
Topics: Alanine; Amelogenesis; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Dental Enamel; Dental Enamel Proteins; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Electrogenic effects of neutral amino acids on neurons of Aplysia californica.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Cyanides; Dinitrophenols; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ganglia; Glutamates; Glutamine; Histidine; Kinetics; Leucine; Membrane Potentials; Mollusca; Neural Conduction; Ouabain; Potassium; Sodium; Stereoisomerism; Temperature | 1976 |
Variation of ribosomal proteins with bacterial growth rate.
Topics: Alanine; Ammonium Chloride; Aspartic Acid; Bacterial Proteins; Carbon Radioisotopes; Cell Fractionation; Culture Media; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glucose; Glycerol; Histidine; Leucine; Ribosomes; Succinates; Tritium; Ultracentrifugation | 1975 |
Specific cyanylation and cleavage at cysteine-104 human hemoglobin alpha-chain. A novel approach to the problem of the alpha-chain tryptic core in the study of haemoglobin variants by "fingerprinting" methods.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Cyanides; Cysteine; Hemoglobins; Hemoglobins, Abnormal; Histidine; Humans; Hydrolysis; Pepsin A; Peptide Fragments; Protein Conformation; Trypsin | 1975 |
Structure of the modified nucleoside Q isolated from Escherichia coli transfer ribonucleic acid. 7-(4,5-cis-Dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanosine.
Topics: Anticodon; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Escherichia coli; Guanosine; Histidine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Protons; RNA, Bacterial; RNA, Transfer; Spectrophotometry, Ultraviolet; Tyrosine | 1975 |
Inhibition of nucleoside Q formation in transfer ribonucleic acid during methionine starvation of relaxed-control Escherichia coli.
Topics: Aspartic Acid; Cyanogen Bromide; Escherichia coli; Guanosine; Histidine; Leucine; Methionine; RNA, Bacterial; RNA, Transfer | 1976 |
Possible effect of blood ammonia on food intake of rats fed amino acid imbalanced diets.
Topics: Amino Acids; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Arginine; Aspartic Acid; Body Weight; Citrulline; Histidine; Ligases; Liver; Male; Nutrition Disorders; Perfusion; Protein Deficiency; Quaternary Ammonium Compounds; Rats; Structure-Activity Relationship; Succinates; Tryptophan | 1975 |
Ligand-exchange chromatography of amino acids on copper-, cobalt- and zinc-chelex 100.
Topics: Amino Acids; Ammonia; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Cobalt; Copper; Cysteine; Glutamates; Histidine; Ion Exchange Resins; Ligands; Lysine; Phenylalanine; Quaternary Ammonium Compounds; Serine; Threonine; Tyrosine; Zinc | 1975 |
Synthesis by conventional methods of human growth hormone peptide fragments. I.
Topics: Alanine; Asparagine; Aspartic Acid; Glutamine; Growth Hormone; Histidine; Humans; Leucine; Lysine; Optical Rotation; Peptides; Phenylalanine; Serine; Threonine; Tyrosine | 1975 |
Amino acid uptake in vivo by the mouse brain and by various regions of the rabbit brain after drug-induced convulsions.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Biological Transport, Active; Blood-Brain Barrier; Brain; Caudate Nucleus; Cerebral Cortex; Histidine; Hypothalamus; Isoleucine; Male; Mesencephalon; Methionine; Mice; Pentylenetetrazole; Phenylalanine; Rabbits; Seizures; Taurine; Thalamus | 1975 |
Alteration of functional properties associated with the change in quaternary structure in unliganded haemoglobin.
Topics: Arginine; Aspartic Acid; Binding Sites; Cysteine; Hemoglobins; Histidine; Humans; Ligands; Oxygen; Oxyhemoglobins; Phytic Acid; Protein Conformation; Structure-Activity Relationship; Sulfhydryl Compounds; Tyrosine | 1975 |
Hemoglobin-Strumica or alpha 2 112(G19) His replaced by Arg beta 2. (With an addendum: hemoglobin-J-Paris-I, alpha 2 12(A10) Ala replaced by Asp beta 2, in the same population).
Topics: Adolescent; Adult; Alanine; Amino Acid Sequence; Amino Acids; Arginine; Aspartic Acid; Child; Female; Genetic Variation; Greece; Hemoglobins, Abnormal; Histidine; Humans; Male; Paris; Pedigree; Yugoslavia | 1975 |
Effect of a low protein diet and isoenergetic amounts of a high protein diet in the weanling rat on the free amino acids of the brain.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Dietary Proteins; DNA; gamma-Aminobutyric Acid; Glycine; Histidine; Male; Methionine; Rats; Stimulation, Chemical | 1975 |
Catalytic strategy of citrate synthase: effects of amino acid changes in the acetyl-CoA binding site on transition-state analog inhibitor complexes.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Aspartic Acid; Binding Sites; Catalysis; Citrate (si)-Synthase; Glycine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Isoelectric Focusing; Isoelectric Point; Magnetic Resonance Spectroscopy; Mutagenesis; Myocardium; Oxaloacetates; Protons; Swine | 1992 |
Active site of (A)BC excinuclease. I. Evidence for 5' incision by UvrC through a catalytic site involving Asp399, Asp438, Asp466, and His538 residues.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Binding Sites; DNA Helicases; DNA-Binding Proteins; Dose-Response Relationship, Radiation; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Histidine; Mutagenesis, Site-Directed; Ultraviolet Rays; Zinc Fingers | 1992 |
Site-specific mutagenesis of Escherichia coli asparaginase II. None of the three histidine residues is required for catalysis.
Topics: Amino Acid Sequence; Asparaginase; Aspartic Acid; Base Sequence; Catalysis; Enzyme Stability; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Spectrometry, Fluorescence; Structure-Activity Relationship; Urea | 1992 |
Asp537, Asp812 are essential and Lys631, His811 are catalytically significant in bacteriophage T7 RNA polymerase activity.
Topics: Aspartic Acid; Base Sequence; Binding Sites; DNA-Directed RNA Polymerases; Histidine; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; T-Phages; Transcription, Genetic; Viral Proteins | 1992 |
Steady-state kinetics and isotope effects on the mutant catalytic trimer of aspartate transcarbamoylase containing the replacement of histidine 134 by alanine.
Topics: Alanine; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Carbon Isotopes; Catalysis; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Macromolecular Substances; Models, Molecular; Mutation; Phosphonoacetic Acid; Recombinant Proteins; Structure-Activity Relationship; Succinates | 1992 |
Side reactions in solid phase synthesis of histidine-containing peptides. Characterization of two major impurities by sample displacement chromatography and FAB-MS.
Topics: Amino Acid Sequence; Aspartic Acid; Chromatography, High Pressure Liquid; Histidine; Molecular Sequence Data; Peptides; Spectrometry, Mass, Fast Atom Bombardment; Succinimides | 1992 |
Histidine regulation of cyclic AMP metabolism in cultured renal epithelial LLC-PK1 cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Arginine Vasopressin; Aspartic Acid; Cells, Cultured; Colforsin; Cyclic AMP; Epithelial Cells; Epithelium; Glutamates; Glutamic Acid; Histidine; Imidazoles; Indomethacin; Kidney; Swine | 1990 |
Site-directed mutagenesis of a thermostable alpha-amylase from Bacillus stearothermophilus: putative role of three conserved residues.
Topics: Amino Acid Sequence; Amylases; Arginine; Aspartic Acid; Bacterial Proteins; Enzyme Stability; Geobacillus stearothermophilus; Histidine; Hot Temperature; Models, Molecular; Molecular Sequence Data; Mutation; Structure-Activity Relationship | 1990 |
Mutation of essential catalytic residues in pig citrate synthase.
Topics: Animals; Antibodies, Monoclonal; Aspartic Acid; Binding Sites; Catalysis; Citrate (si)-Synthase; Epitopes; Escherichia coli; Histidine; Hydrogen Bonding; Kinetics; Mutation; Protein Conformation; Recombinant Proteins; Sequence Homology, Nucleic Acid; Swine | 1990 |
Substitution of aspartic acid-686 by histidine or asparagine in the human androgen receptor leads to a functionally inactive protein with altered hormone-binding characteristics.
Topics: Adult; Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Base Sequence; Chloramphenicol O-Acetyltransferase; Codon; Exons; Female; Fibroblasts; HeLa Cells; Histidine; Humans; Kinetics; Male; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Pedigree; Polymerase Chain Reaction; Receptors, Androgen; Recombinant Fusion Proteins; Skin; Transfection | 1991 |
Histidine pKa shifts accompanying the inactivating Asp121----Asn substitution in a semisynthetic bovine pancreatic ribonuclease.
Topics: Animals; Asparagine; Aspartic Acid; Cattle; Histidine; In Vitro Techniques; Magnetic Resonance Spectroscopy; Ribonucleases; Structure-Activity Relationship | 1991 |
Structural and functional effects of mutations altering the subunit interface of mitochondrial malate dehydrogenase.
Topics: Acetates; Acetic Acid; Amino Acid Sequence; Asparagine; Aspartic Acid; Blotting, Western; Chromatography, Gel; Codon; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Macromolecular Substances; Malate Dehydrogenase; Mitochondria; Molecular Sequence Data; Mutagenesis; Saccharomyces cerevisiae; Structure-Activity Relationship | 1991 |
Heteronuclear 2D NMR studies of an engineered insulin monomer: assignment and characterization of the receptor-binding surface by selective 2H and 13C labeling with application to protein design.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; DNA Mutational Analysis; Histidine; Humans; Hydrogen-Ion Concentration; Insulin; Lysine; Macromolecular Substances; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptide Fragments; Proline; Protein Conformation; Protein Engineering; Receptor, Insulin; Trypsin | 1991 |
Different amino acid substitutions at the same position in the nucleotide-binding site of aspartate transcarbamoylase have diverse effects on the allosteric properties of the enzyme.
Topics: Adenosine Triphosphate; Allosteric Regulation; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Carbamyl Phosphate; Cytidine Triphosphate; DNA Mutational Analysis; Histidine; Lysine; Phosphonoacetic Acid; Structure-Activity Relationship | 1991 |
Phosphorylation assays for proteins of the two-component regulatory system controlling chemotaxis in Escherichia coli.
Topics: Aspartic Acid; Bacterial Proteins; Chemotactic Factors; Chemotaxis; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Escherichia coli; Histidine; Indicators and Reagents; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Models, Biological; Phosphorylation; Signal Transduction | 1991 |
Determinants of visual pigment absorbance: role of charged amino acids in the putative transmembrane segments.
Topics: Amino Acid Sequence; Animals; Arginine; Aspartic Acid; Cattle; Gene Expression; Glutamates; Histidine; Lysine; Membrane Proteins; Molecular Sequence Data; Molecular Structure; Mutation; Retinal Pigments; Retinaldehyde; Rhodopsin; Spectrophotometry | 1990 |
Ab initio study on the transition state of acylation step of trypsin catalysis.
Topics: Acylation; Anions; Aspartic Acid; Catalysis; Histidine; Models, Chemical; Models, Molecular; Molecular Structure; Protons; Thermodynamics; Trypsin | 1990 |
The catalytic site of Escherichia coli aspartate transcarbamylase: interaction between histidine 134 and the carbonyl group of the substrate carbamyl phosphate.
Topics: Amino Acid Sequence; Aspartate Carbamoyltransferase; Aspartic Acid; Bacterial Proteins; Binding Sites; Carbamyl Phosphate; Catalysis; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphonoacetic Acid; Protein Binding; Substrate Specificity; Succinates; Succinic Acid | 1990 |
Superactive insulins.
Topics: Aspartic Acid; Histidine; Humans; Insulin; Receptor, Insulin | 1990 |
pH-induced denaturation of proteins: a single salt bridge contributes 3-5 kcal/mol to the free energy of folding of T4 lysozyme.
Topics: Aspartic Acid; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Muramidase; Mutation; Potassium Chloride; Protein Conformation; Protein Denaturation; T-Phages; Thermodynamics; X-Ray Diffraction | 1990 |
[Cri-du-chat disease: plasma and urinary amino acids].
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Asparagine; Aspartic Acid; Child; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosome Disorders; Chromosome Mapping; Chromosomes, Human, Pair 5; Cri-du-Chat Syndrome; Female; Histidine; Humans; Intellectual Disability; Male; Models, Biological; Purine-Pyrimidine Metabolism, Inborn Errors | 1990 |
Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.
Topics: Animals; Aspartic Acid; Base Sequence; Cell Line; Complement C4a; Complement C4b; Genetic Vectors; Hemolysis; Histidine; Humans; Kinetics; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Plasmids; Recombinant Proteins; Transfection | 1990 |
Plasma amino acid concentrations in premature infants: effect of sampling site.
Topics: Alanine; Amino Acids; Aspartic Acid; Blood Specimen Collection; Capillaries; Chromatography, High Pressure Liquid; Glycine; Heel; Histidine; Humans; Infant, Newborn; Infant, Premature; Serine; Tryptophan; Veins | 1989 |
Contribution of amino acids in protective solutions to postischemic functional recovery of canine kidneys.
Topics: Animals; Aorta; Aspartic Acid; Diuresis; Dogs; Female; Glomerular Filtration Rate; Glucose; Histidine; Ischemia; Kidney; Kidney Function Tests; Male; Mannitol; Oxygen Consumption; Perfusion; Potassium Chloride; Procaine; Regional Blood Flow; Reperfusion | 1989 |
Utilization of amino acids and peptides by Fusobacterium nucleatum.
Topics: Amino Acids; Aspartic Acid; Culture Media; Fusobacterium; Glutamates; Glutamic Acid; Histidine; Lysine; Methionine; Peptides | 1989 |
Histidine and proline are important sites of free radical damage to proteins.
Topics: Animals; Aspartic Acid; Free Radicals; Glutamates; Glutamic Acid; Histidine; In Vitro Techniques; Proline; Proteins | 1989 |
Segmented anisotropic refinement of bovine ribonuclease A by the application of the rigid-body TLS model.
Topics: Animals; Arginine; Asparagine; Aspartic Acid; Cattle; Chemical Phenomena; Chemistry, Physical; Glutamates; Glutamine; Histidine; Mathematics; Models, Molecular; Phenylalanine; Ribonuclease, Pancreatic; Sulfates; Tyrosine; X-Ray Diffraction | 1989 |
Investigation of an active site histidine-aspartate couple in Trimeresurus flavoviridis phospholipase A2.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Benzenesulfonates; Binding Sites; Crotalid Venoms; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Methylation; Molecular Sequence Data; Phospholipases; Phospholipases A; Phospholipases A2; Snakes | 1989 |
Incorporation of histidine into the pyrimidine moiety of thiamin in Saccharomyces cerevisiae.
Topics: Aspartic Acid; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Histidine; Mass Spectrometry; Nitrogen Radioisotopes; Pyrimidines; Saccharomyces cerevisiae; Thiamine | 1989 |
NMR analysis of site-specific mutants of yeast phosphoglycerate kinase. An investigation of the triose-binding site.
Topics: Arginine; Aspartic Acid; Binding Sites; Binding, Competitive; Energy Transfer; Glyceric Acids; Histidine; Magnetic Resonance Spectroscopy; Methionine; Mutation; Phosphoglycerate Kinase; Protein Conformation; Saccharomyces cerevisiae; Structure-Activity Relationship | 1989 |
A cysteine-histidine-aspartate catalytic triad is involved in glutamine amide transfer function in purF-type glutamine amidotransferases.
Topics: Amino Acid Sequence; Anthranilate Synthase; Aspartic Acid; Binding Sites; Cysteine; Escherichia coli; Histidine; Molecular Sequence Data; Mutation; Nitrogenous Group Transferases; Transferases | 1989 |
On the role of histidine and tyrosine residues in E. coli asparaginase. Chemical modification and 1H-nuclear magnetic resonance studies.
Topics: Asparaginase; Aspartic Acid; Bromosuccinimide; Chemical Phenomena; Chemistry; Diethyl Pyrocarbonate; Escherichia coli; Histidine; Magnetic Resonance Spectroscopy; Spectrophotometry; Tetrazoles; Tyrosine | 1989 |
Enzyme elements involved in the interconversion of L-carbamylaspartate and L-dihydroorotate by dihydroorotase from Clostridium oroticum.
Topics: Amidohydrolases; Aspartic Acid; Catalysis; Clostridium; Cobalt; Cyclization; Diethyl Pyrocarbonate; Dihydroorotase; Histidine; Hydrogen-Ion Concentration; Kinetics; Orotic Acid; Zinc | 1985 |
Sequence of a peptide susceptible to mixed-function oxidation. Probable cation binding site in glutamine synthetase.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Escherichia coli; Glutamate-Ammonia Ligase; Histidine; Kinetics; Mixed Function Oxygenases; Peptide Fragments; Trypsin | 1986 |
Huntington's disease: studies on brain free amino acids.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Aspartic Acid; Brain; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Histidine; Humans; Huntington Disease; Lysine; Male; Middle Aged; Putamen; Serine; Taurine | 1988 |
The role of an active site histidine in the catalytic mechanism of aspartate transcarbamoylase.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Carbamyl Phosphate; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Phosphonoacetic Acid; Succinates; Succinic Acid | 1988 |
A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway.
Topics: Animals; Aspartic Acid; Histidine; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Transgenic; Microscopy, Electron; Mutation; Proinsulin | 1988 |
Substitutions in the active site of chloramphenicol acetyltransferase: role of a conserved aspartate.
Topics: Alanine; Arginine; Asparagine; Aspartic Acid; Binding Sites; Chloramphenicol; Chloramphenicol O-Acetyltransferase; Cysteine; Drug Stability; Escherichia coli; Histidine; Hot Temperature; Hydrogen Bonding; Kinetics; Mutation; Structure-Activity Relationship; Sulfhydryl Reagents | 1988 |
Peptide models of electrostatic interactions in proteins: NMR studies on two beta-turn tetrapeptides containing Asp-His and Asp-Lys salt bridges.
Topics: Aspartic Acid; Electrochemistry; Histidine; Indicators and Reagents; Lysine; Magnetic Resonance Spectroscopy; Oligopeptides; Protein Conformation; Proteins; Salts | 1986 |
The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis.
Topics: Animals; Asparagine; Aspartic Acid; Binding Sites; Cattle; Computer Simulation; Crystallography; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Protein Conformation; Rats; Serine; Structure-Activity Relationship; Trypsin | 1987 |
An investigation of the contribution made by the carboxylate group of an active site histidine-aspartate couple to binding and catalysis in lactate dehydrogenase.
Topics: Aspartic Acid; Binding Sites; Geobacillus stearothermophilus; Histidine; Kinetics; L-Lactate Dehydrogenase; Mutation; Protein Binding; Protein Conformation | 1988 |
Haem-apoprotein interactions detected by resonance Raman scattering in Mb- and Hb-derivates lacking the saltbridge His146 beta-Asp94 beta.
Topics: Animals; Apoproteins; Aspartic Acid; Heme; Hemoglobins; Histidine; Hydrogen-Ion Concentration; Myoglobin; Spectrum Analysis, Raman; Structure-Activity Relationship; Whales | 1985 |
The molecular abnormality of albumin Parklands: 365 Asp----His.
Topics: Aged; Amino Acid Sequence; Aspartic Acid; Blood Protein Disorders; Blood Protein Electrophoresis; Genetic Variation; Histidine; Humans; Male; Serum Albumin | 1985 |
Axonal transport of proteins in retinal ganglion cells. Amino acid incorporation into rapidly transported proteins and distribution of radioactivity to the lateral geniculate body and the superior colliculus.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Axonal Transport; Cysteine; Female; Geniculate Bodies; Glycine; Histidine; Leucine; Lysine; Male; Methionine; Nerve Tissue Proteins; Optic Nerve; Phenylalanine; Proline; Rabbits; Retina; Superior Colliculi; Tritium; Tryptophan | 1972 |
The effects of metabolic inhibitors on amino acid uptake and the levels of ATP, Na+, and K+ in incubated slices of mouse brain.
Topics: Adenosine Triphosphate; Amino Acids; Amobarbital; Animals; Antimetabolites; Aspartic Acid; Brain; Cyanides; Dinitrophenols; Ethanol; Ethylmaleimide; Fluorides; Fluoroacetates; Glutamates; Gramicidin; Histidine; Iodoacetates; Iodobenzoates; Leucine; Lysine; Mice; Oligomycins; Ouabain; Potassium; Sodium; Valinomycin | 1974 |
Activity of a transfer RNA modifying enzyme during the development of Drosophila and its relationship to the su(s) locus.
Topics: Amino Acyl-tRNA Synthetases; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Drosophila melanogaster; Genes; Histidine; Metamorphosis, Biological; Models, Biological; Mutation; Oligonucleotides; Ribonucleotides; RNA, Transfer; Spectrophotometry, Ultraviolet; Transcription, Genetic; Tritium; Tyrosine | 1973 |
Production of lesions in various tissues by amino acids.
Topics: Amino Acids; Animals; Aspartic Acid; Carbamates; Dermatitis, Contact; Erythema; Glutamates; Guinea Pigs; Haplorhini; Histidine; Injections, Intraperitoneal; Intestines; Kidney; Liver; Macaca; Ornithine; Rabbits; Tyrosine | 1973 |
Role of methionine in biosynthesis of prodigiosin by Serratia marcescens.
Topics: Alanine; Aspartic Acid; Carbon Radioisotopes; Cell-Free System; Chemical Phenomena; Chemistry; Culture Media; Escherichia coli; Glutamates; Histidine; Methionine; Methyltransferases; Mutation; Prodigiosin; Proline; Pseudomonas aeruginosa; S-Adenosylmethionine; Serine; Serratia marcescens; Stereoisomerism; Tetrahydrofolates | 1973 |
Ionization behavior of the histidine residue in the catalytic triad of serine proteases. Mechanistic implications.
Topics: Aspartic Acid; Carbon Isotopes; Carbon Radioisotopes; Catalysis; Chemical Phenomena; Chemistry; Drug Stability; Endopeptidases; Histidine; Hydrogen-Ion Concentration; Imidazoles; Ions; Magnetic Resonance Spectroscopy; Myxococcales; Protein Binding; Protons; Serine | 1973 |
Carbon nuclear magnetic resonance studies of the histidine residue in alpha-lytic protease. Implications for the catalytic mechanism of serine proteases.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Carbon Isotopes; Carbon Radioisotopes; Catalysis; Chromatography, Ion Exchange; Endopeptidases; Histidine; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Magnetic Resonance Spectroscopy; Myxococcales; Protein Binding; Protein Conformation; Serine; Serine Endopeptidases; Spectrophotometry, Ultraviolet | 1973 |
Regulation of biosynthesis of secondary metabolites. XV. Isolation and characterization of auxotrophic mutants in Streptomyces aureofaciens.
Topics: Acridines; Arginine; Aspartic Acid; Bacteriological Techniques; Chlortetracycline; Demeclocycline; Dose-Response Relationship, Radiation; Freeze Drying; Histidine; Methionine; Mutation; Nitrosoguanidines; Streptomyces aureofaciens; Tetracycline; Ultraviolet Rays | 1973 |
D-amino acids in the cell pool of bacteria.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Bacillus subtilis; Bacteria; Chromatography, Thin Layer; Clostridium; Culture Media; Escherichia coli; Glutamates; Histidine; Hydrogen-Ion Concentration; Lactobacillus; Leucine; Proline; Serine; Spectrophotometry; Staphylococcus; Stereoisomerism; Temperature; Tyrosine | 1974 |
Purification and properties of 5-hydroxytryptophan decarboxylase from monkey small intestine.
Topics: 5-Hydroxytryptophan; Amines; Animals; Aspartic Acid; Benzoates; Carboxy-Lyases; Edetic Acid; Glutamates; Glutathione; Haplorhini; Histidine; Intestine, Small; Keto Acids; Kinetics; Male; Mercaptoethanol; Metals; Phenylalanine; Pyridoxal Phosphate; Tryptophan; Tyrosine | 1970 |
Mechanism of action of alpha-1-antitrypsin.
Topics: alpha 1-Antitrypsin; Amino Acids; Anilides; Arginine; Aspartic Acid; Benzoates; Binding Sites; Binding, Competitive; Cholinesterase Inhibitors; Chymotrypsin; Fibrinolysin; Glyoxal; Histidine; Isoflurophate; Leucine; Lysine; Nitro Compounds; Pancreatic Elastase; Peptide Hydrolases; Protease Inhibitors; Serine; Structure-Activity Relationship; Subtilisins; Thrombin; Trypsin Inhibitors | 1973 |
Electron paramagnetic resonance study of free radical products of the reaction of ninhydrin with amino acids, peptides and proteins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Dipeptides; Electron Spin Resonance Spectroscopy; Ethanol; Free Radicals; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Lysine; Peptides; Phenylalanine; Proline; Proteins; Serine; Solutions; Tryptophan; Tyrosine; Valine | 1970 |
Behavior of angiotensin octapeptides and dinitrophenyl-angiotensin during chromatography on polyacrylamide and dextran gels.
Topics: Angiotensin II; Asparagine; Aspartic Acid; Bacitracin; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Dextrans; Dinitrophenols; Gels; Histidine; Hydrogen-Ion Concentration | 1970 |
Staphylococcal nuclease (Foggi strain). II. The amino acid sequence.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Chromatography, Ion Exchange; Chymotrypsin; Cyanides; Glutamates; Histidine; Leucine; Peptides; Phosphoric Monoester Hydrolases; Staphylococcus; Trypsin | 1971 |
Replacement of Mg 2+ by monovalent cations in aminoacyl transfer RNA formation.
Topics: Acetates; Adenosine Triphosphate; Ammonium Chloride; Aspartic Acid; Chlorides; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Paper; Dialysis; Diphosphates; Edetic Acid; Enzyme Activation; Escherichia coli; Histidine; Hydroxamic Acids; Hydroxyapatites; Hydroxylamines; Isoleucine; Kinetics; Leucine; Ligases; Lithium; Lysine; Magnesium; Methionine; Phenylalanine; Phosphorus Isotopes; Potassium Chloride; RNA, Transfer; Sodium Chloride; Tryptophan; Tyrosine; Valine | 1971 |
Regulation and mechanism of phosphoribosylpyrophosphate synthetase: repression by end products.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Aspartic Acid; Cell-Free System; Culture Media; Enzyme Repression; Fluorometry; Histidine; Nucleotides; Oxidoreductases; Phosphates; Phosphoric Monoester Hydrolases; Phosphorus Isotopes; Phosphotransferases; Salmonella typhimurium; Transferases; Tryptophan; Uridine | 1971 |
Alterations of free amino acids concentrations in cat brain induced by rapid eye movement sleep deprivation.
Topics: Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cats; Caudate Nucleus; Cysteine; Frontal Lobe; Glutamates; Glycine; Hippocampus; Histidine; Lysine; Male; Occipital Lobe; Reticular Formation; Serine; Sleep Deprivation; Sleep, REM; Thalamus; Threonine; Tyrosine | 1971 |
Physicochemical studies of the relation between structure and function in hemoglobin Hiroshima (HC3 , histidine leads to aspartate).
Topics: Aspartic Acid; Binding Sites; Blood Protein Electrophoresis; Chromatography, Ion Exchange; Disulfides; Electron Spin Resonance Spectroscopy; Glycerophosphates; Hemoglobins, Abnormal; Histidine; Humans; Japan; Kinetics; Oxygen; Protein Binding; Protein Conformation; Pyridines; Spectrophotometry; Structure-Activity Relationship; Sulfhydryl Compounds; Thermodynamics; Ultraviolet Rays | 1972 |
The altered patterns of transfer RNA in SV40-infected and transformed cells.
Topics: Acylation; Amino Acids; Amino Acyl-tRNA Synthetases; Ammonium Sulfate; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; DNA, Viral; Electron Transport; Haplorhini; Histidine; Kidney; Nucleic Acid Hybridization; Ribosomes; RNA, Transfer; Simian virus 40; Tritium | 1972 |
Comparative transport activity of intact cells, membrane vesicles, and mesosomes of Bacillus licheniformis.
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Biological Transport, Active; Carbon Isotopes; Cell Fractionation; Cell Membrane; Cell Membrane Permeability; Centrifugation, Density Gradient; Chromatography, Paper; Culture Media; Glutamates; Histidine; Inclusion Bodies; Light; Lysine; NAD; Sodium; Stereoisomerism; Succinates; Vitamin K | 1973 |
Potassium-induced release of amino acids from cerebral cortex and spinal cord slices of the rat.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Carbon Radioisotopes; Cerebral Cortex; Glutamates; Glycine; Histidine; In Vitro Techniques; Lysine; Male; Membrane Potentials; Phenylalanine; Potassium; Proline; Rats; Sodium; Spinal Cord; Synaptic Transmission; Synaptosomes; Tritium; Tyrosine | 1974 |
Chromatographic changes in specific tRNAs after reaction with cyanogen bromide and sodium periodate.
Topics: Amino Acyl-tRNA Synthetases; Aspartic Acid; Carbon Radioisotopes; Chromatography, Thin Layer; Cyanogen Bromide; Diptera; Drosophila melanogaster; Electrophoresis; Histidine; Houseflies; Nucleosides; Periodic Acid; RNA, Transfer; Sodium; Species Specificity; Transfer RNA Aminoacylation; Tritium; Tyrosine | 1974 |
Transfer RNA genes in mitochondrial DNA of grande (wild-type) yeast.
Topics: Amino Acyl-tRNA Synthetases; Aspartic Acid; Chromatography; Cytoplasm; Cytosol; DNA, Mitochondrial; Escherichia coli; Genes; Glutamates; Histidine; Hot Temperature; Kinetics; Lysine; Mitochondria; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Proline; RNA, Transfer; Saccharomyces cerevisiae; Serine; Silicon Dioxide; Tritium; Tyrosine | 1974 |
The site of the inhibitory action of salicylate on protein biosynthesis in vitro.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Carbon Isotopes; Glutamates; Histidine; In Vitro Techniques; Leucine; Ligases; Liver; Phosphorus Isotopes; Protein Biosynthesis; Rats; Ribosomes; RNA, Transfer; Salicylates; Sulfur Isotopes; Ultracentrifugation | 1971 |
Lipolytic and hypoglycemic compounds obtained from cystoseira barbata J. Ag.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Blood Glucose; Chromatography, Gel; Chromatography, Paper; Eukaryota; Glutamine; Histidine; Leucine; Lipid Metabolism; Lysine; Methionine; Peptide Fragments; Rabbits; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
The absorption of a mixture of amino acids by rat small intestine.
Topics: Amino Acids; Animals; Aspartic Acid; Autoanalysis; Glycine; Histidine; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Lithium; Male; Methionine; Potassium; Rats; Sodium | 1974 |
Independence of amino acid uptake from tissue swelling in incubated slices of brain.
Topics: Absorption; Adenosine Triphosphate; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Chlorine; Cyanides; Dextrans; Glutamates; Glycine; Histidine; In Vitro Techniques; Inulin; Iodobenzoates; Leucine; Mercury; Mice; Mice, Inbred Strains; Polyethylene Glycols; Potassium; Sodium; Sulfonic Acids; Valine; Water-Electrolyte Balance | 1974 |
[Amino acid levels in the blood serum of patients with chronic colitis].
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea | 1974 |
Free amino acid levels in the boll weevil (Coleoptera: Curculionidae): the effect of five different diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography, Gas; Coleoptera; Diet; Dietary Proteins; Glutamates; Glycine; Gossypium; Histidine; Isoleucine; Leucine; Male; Mass Spectrometry; Methionine; Phenylalanine; Proline; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Free amino acids in the haemocytes and plasma of the larva of Calliphora vicina.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Blood Cells; Blood Coagulation; Diptera; Glutamates; Glutamine; Glycine; Hemolymph; Histidine; Isoleucine; Larva; Leucine; Lysine; Methionine; Phenylalanine; Plasma; Proline; Serine; Taurine; Threonine; Tyrosine; Valine | 1974 |
Studies on the fractionation of total transfer ribonucleic acid and purification of an alanine transfer ribonucleic acid from chick embryo.
Topics: Alanine; Animals; Aspartic Acid; Chemical Fractionation; Chick Embryo; Chromatography, Ion Exchange; Histidine; Isoleucine; Lysine; Proline; Ribonucleases; RNA, Transfer; Serine; Tyrosine; Valine | 1974 |
Sodium dependence of the amino acid transport in the proximal convolution of the rat kidney.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport, Active; Choline; Glucose; Glycine; Histidine; Kidney Tubules, Proximal; Lysine; Male; Ornithine; Phenylalanine; Proline; Rats; Sodium | 1974 |
The effect of removal of C-terminal residues on cooperative interactions in hemoglobin.
Topics: Arginine; Aspartic Acid; Hemoglobins; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen-Ion Concentration; Lysine; Macromolecular Substances; Oxygen; Protein Binding; Structure-Activity Relationship; Tyrosine | 1972 |
Use of 19 F-nuclear magnetic resonance spectroscopy for detection of protein conformation changes: application to lysozyme, ribonuclease and hemoglobin.
Topics: Acetone; Acylation; Aspartic Acid; Binding Sites; Cytosine Nucleotides; Fluorine; Fluoroacetates; Glyceric Acids; Hemoglobins; Histidine; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Methemoglobin; Models, Chemical; Muramidase; Oligosaccharides; Organophosphorus Compounds; Oxygen; Peptides; Protein Binding; Protein Conformation; Ribonucleases | 1972 |
High-resolution proton NMR studies of low affinity hemoglobins.
Topics: Asparagine; Aspartic Acid; Binding Sites; Carbon Isotopes; Deuterium; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen-Ion Concentration; Iron; Japan; Kansas; Magnetic Resonance Spectroscopy; Methylation; Mutation; Oxyhemoglobins; Protein Binding; Protein Conformation; Threonine; Tyrosine | 1973 |
The decarboxylation of amino acids by bacteria derived from human dental plaque.
Topics: Amino Acids; Aspartic Acid; Bacteria; Carbon Dioxide; Carbon Radioisotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Decarboxylation; Dental Plaque; Glutamates; Histidine; Humans; Hydrogen-Ion Concentration; Lysine; Ornithine; Pyridoxal Phosphate | 1974 |
Possible anticodon sequences of tRNA His , tRNA Asm , and tRNA Asp from Escherichia coli B. Universal presence of nucleoside Q in the first postion of the anticondons of these transfer ribonucleic acids.
Topics: Asparagine; Aspartic Acid; Base Sequence; Carbon Isotopes; Chromatography, Ion Exchange; Escherichia coli; Genetic Code; Histidine; Nucleosides; Polynucleotides; Protein Binding; Ribonucleases; Ribosomes; RNA, Bacterial; RNA, Transfer; Spectrophotometry; Stimulation, Chemical | 1972 |
Isolation and characterization of 2-methyladenosine from Escherichia coli tRNA Glu 2 , tRNA Asp 1 , tRNA His 1 and tRNA Arg .
Topics: Adenosine; Adenosine Monophosphate; Alkaline Phosphatase; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Escherichia coli; Glutamates; Histidine; Hydrolysis; Methylation; Ribonucleases; RNA, Bacterial; RNA, Transfer; Spectrophotometry; Ultraviolet Rays | 1972 |
The pH dependence and quenching of the fluorescence of asparaginase from Escherichia coli B.
Topics: Asparaginase; Asparagine; Aspartic Acid; Binding Sites; Escherichia coli; Fluorescence; Histidine; Hydrogen-Ion Concentration; Protein Conformation; Spectrometry, Fluorescence; Time Factors; Tryptophan | 1972 |
Phosphoenolpyruvate carboxylase of Escherichia coli: alteration of allosteric properties by photooxidation.
Topics: Allosteric Regulation; Aspartic Acid; Binding Sites; Carboxy-Lyases; Coenzyme A; Dioxins; Enzyme Activation; Escherichia coli; Ethylmaleimide; Fatty Acids, Unsaturated; Fructosephosphates; Histidine; Hydrogen-Ion Concentration; Kinetics; Light; Methylene Blue; Oxaloacetates; Phosphoenolpyruvate; Radiation Effects | 1972 |
The acidic amino-acid permease of Aspergillus nidulans.
Topics: Amino Acids; Asparagine; Aspartic Acid; Aspergillus nidulans; Azides; Biological Transport, Active; Carbon Isotopes; Chromatography; Cyanides; Glutamates; Histidine; Hydrogen-Ion Concentration; Kinetics; Membrane Transport Proteins; Phenylalanine; Sulfur Isotopes; Temperature; Valinomycin | 1973 |
Nucleotide sequences of transfer ribonucleic acids.
Topics: Alanine; Arginine; Aspartic Acid; Base Sequence; Biological Evolution; Escherichia coli; Evaluation Studies as Topic; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Serine; Species Specificity; Tryptophan; Tyrosine; Valine | 1974 |
Nuclear magnetic resonance titration curves of histidine ring protons. 3. Ribonuclease.
Topics: Animals; Aspartic Acid; Carboxylic Acids; Cattle; Histidine; Hydrogen-Ion Concentration; Imidazoles; Ions; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Pancreas; Protons; Ribonucleases; X-Ray Diffraction | 1972 |
High resolution nuclear magnetic resonance study of the histidine--aspartate hydrogen bond in chymotrypsin and chymotrypsinogen.
Topics: Aspartic Acid; Binding Sites; Chymotrypsin; Chymotrypsinogen; Histidine; Hydrogen; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Biology | 1972 |
The ligand-binding properties of hemoglobin Hiroshima ( 2 2 146asp ).
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Butyrates; Carbon Monoxide; Crystallography; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen-Ion Concentration; Inositol; Japan; Kinetics; Ligands; Nitriles; Oxygen; Peptides; Photolysis; Protein Binding; Protein Conformation; Protons; Spectrophotometry; Sulfites | 1972 |
Cerebral amino acid uptake in vivo in newborn mice.
Topics: Age Factors; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Blood-Brain Barrier; Brain; Cell Membrane Permeability; Dose-Response Relationship, Drug; Glycine; Histidine; Isoleucine; Methionine; Mice; Serine; Threonine; Tryptophan; Valine | 1972 |
Amino acid metabolism in chameleon liver.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Citrulline; Female; Glutamates; Glutamine; Glycine; Histidine; Keto Acids; Liver; Lizards; Lysine; Male; Methionine; Ornithine; Phenylalanine; Pyruvates; Serine; Threonine; Tryptophan | 1972 |
Haemoglobin Q India (alpha 64(E13) aspartic acid histidine) associated with beta-thalassemia observed in three Sindhi families.
Topics: Adult; Amino Acid Sequence; Aspartic Acid; Blood Protein Electrophoresis; Child; Child, Preschool; Chromatography, DEAE-Cellulose; Electrophoresis, Starch Gel; Female; Hemoglobins, Abnormal; Histidine; Humans; India; Infant; Male; Pedigree; Thalassemia | 1972 |
Assimilation and toxicity of exogenous amino acids in the methane-oxidizing bacterium Methylococcus capsulatus.
Topics: Amino Acids; Aspartic Acid; Bacteria; Carbon Isotopes; Histidine; Homoserine; Lysine; Methionine; Phenylalanine; Threonine; Tyrosine | 1972 |
The chemical composition of wool. XI. Separation and analysis of exocuticle and endocuticle.
Topics: Amino Acids; Animals; Aspartic Acid; Coloring Agents; Cysteine; Cystine; Formates; Histidine; Leucine; Lysine; Methionine; Microscopy, Electron; Phenylalanine; Proline; Pronase; Sheep; Structure-Activity Relationship; Threonine; Tyrosine; Wool | 1972 |
Schistosoma mansoni and Schistosoma japonicum: utilization of amino acids.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Biomphalaria; Carbon Dioxide; Carbon Isotopes; Female; Glutamates; Histidine; Male; Mice; Proline; Schistosoma; Schistosoma mansoni; Sex Factors; Snails; Species Specificity; Tyrosine | 1972 |
Affinity labeling of aspartate aminotransferase isozymes by bromopyruvate.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Binding Sites; Bromine; Carbon Isotopes; Chemical Phenomena; Chemistry; Circular Dichroism; Cysteine; Cytoplasm; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Lysine; Mitochondria, Muscle; Myocardium; Peptides; Pyruvates; Spectrophotometry, Ultraviolet; Sulfinic Acids; Swine | 1973 |
Effects of some amino acids on the horizontal cell membrane potential in the isolated carp retina.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cyprinidae; Dark Adaptation; Glutamates; Glutamine; Glycine; Histidine; In Vitro Techniques; Leucine; Membrane Potentials; Photic Stimulation; Retina | 1973 |
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cataract; Cystine; Diet; Glutamates; Glycine; Histidine; Isoleucine; Lens, Crystalline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Serine; Threonine; Triparanol; Tyrosine; Valine | 1973 |
A model of pancreatic lipase and the orientation of enzymes at interfaces.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Binding, Competitive; Chemical Phenomena; Chemistry; Histidine; Leucine; Lipase; Models, Chemical; Pancreas; Protein Binding; Protein Conformation; Serine | 1973 |
Hemoglobin Winnipeg: alpha2 75 Asp leads to Tyr beta2.
Topics: Aged; Amino Acid Sequence; Amino Acids; Aspartic Acid; Chromatography, Ion Exchange; Chromatography, Paper; Electrophoresis, Paper; Hemoglobins, Abnormal; Histidine; Humans; Lysine; Male; Manitoba; Methionine; Peptides; Thermolysin; Tyrosine | 1973 |
Structure of deoxyhaemoglobin Yakima: a high-affinity mutant form exhibiting oxy-like 1 2 subunit interactions.
Topics: Aspartic Acid; Carbon Monoxide; Crystallization; Glutamates; Hemoglobins, Abnormal; Histidine; Microscopy, Electron; Models, Structural; Oxygen; Peptides; Protein Conformation; Washington; X-Ray Diffraction | 1973 |
Nitrogen metabolism in lambs fed soybean meal treated with heat, formalin and tannic acid.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Aspartic Acid; Cellulose; Dietary Proteins; Feces; Formaldehyde; Glycine; Glycine max; Histidine; Hot Temperature; Leucine; Lysine; Male; Nitrogen; Rumen; Sheep; Tannins; Urea; Valine | 1973 |
The equilibrium unfolding parameters of horse and sperm whale myoglobin. Effects of guanidine hydrochloride, urea, and acid.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Cetacea; Crystallography; Drug Stability; Guanidines; Histidine; Horses; Hydrogen-Ion Concentration; Iron; Mathematics; Myoglobin; Protein Binding; Protein Conformation; Protein Denaturation; Species Specificity; Spectrophotometry, Ultraviolet; Thermodynamics; Urea | 1973 |
Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. Crystal structure determination and stereochemistry of the contact region.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Cattle; Fourier Analysis; Glycine; Histidine; Kinetics; Lysine; Models, Structural; Pancreas; Protein Conformation; Serine; Trypsin; Trypsin Inhibitors; X-Ray Diffraction | 1973 |
Proton magnetic resonance studies of des-(121-124)-ribonuclease A.
Topics: Animals; Aspartic Acid; Binding Sites; Carboxypeptidases; Cattle; Cytosine Nucleotides; Deuterium; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Pancreas; Protein Binding; Protein Conformation; Ribonucleases; Spectrophotometry, Ultraviolet | 1973 |
Changes in the tertiary structure of alpha-chymotrypsin with change in pH: p4 4.2-6.7.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; Macromolecular Substances; Methionine; Models, Structural; Phenylalanine; Protein Binding; Protein Conformation; Serine; Tyrosine; Uranium; X-Ray Diffraction | 1973 |
Activation of chymotrypsinogen-A. An hypothesis based upon comparison of the crystal structures of chymotrypsinogen-A and alpha-chymotrypsin.
Topics: Aspartic Acid; Catalysis; Chymotrypsin; Chymotrypsinogen; Enzyme Activation; Histidine; Orientation; Protein Binding; Protein Conformation | 1973 |
Investigation of the active site of papain with fluorescent probes.
Topics: Aspartic Acid; Binding Sites; Cysteine; Dioxins; Disulfides; Fluorescent Dyes; Histidine; Hydrogen-Ion Concentration; Nitro Compounds; Oxadiazoles; Papain; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1973 |
Amino acid metabolism in chameleon tissues.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brain; Citrulline; Glutamates; Glutamine; Glycine; Histidine; Ketoglutaric Acids; Kidney; Liver; Lysine; Muscles; Myocardium; Ornithine; Oxaloacetates; Proline; Pyruvates; Reptiles; Serine; Tryptophan | 1973 |
A molecular orbital study on the enzymic reaction mechanism of alpha-chymotrypsin.
Topics: Acetamides; Acetates; Activation Analysis; Acylation; Aspartic Acid; Chymotrypsin; Histidine; Hydrolysis; Molecular Biology; Protein Binding; Quantum Theory; Serine; X-Ray Diffraction | 1973 |
Acute distribution of 14C-amino acids in mice as determined by whole-body autoradiography: adjunct for radiopharmaceutical synthesis.
Topics: Adrenal Glands; Alanine; Amino Acids; Animals; Aspartic Acid; Autoradiography; Brain; Carbon Radioisotopes; Gastric Mucosa; Glutamates; Histidine; Kidney; Liver; Lung; Lysine; Mice; Myocardium; Pancreas; Radionuclide Imaging; Salivary Glands; Spleen; Thymus Gland | 1973 |
Proteins lacking certain amino acids.
Topics: Arginine; Aspartic Acid; Cysteine; Glutamates; Histidine; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Proteins; Tryptophan; Tyrosine; Valine | 1974 |
In vitro uptake of beta-alanine into rabbit retinal neurons.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Biological Transport, Active; Dinitrophenols; Glutamates; Glycine; Histidine; Leucine; Neurons; Ouabain; Rabbits; Retina; Taurine; Temperature | 1974 |
Localization of the histidine-rich protein in keratohyalin: a morphologic and macromolecular marker in epidermal differentiation.
Topics: Alanine; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cell Differentiation; Cytoplasmic Granules; Electrophoresis, Polyacrylamide Gel; Glutamates; Glycine; Histidine; Histocytochemistry; Keratins; Macromolecular Substances; Microscopy, Electron; Microscopy, Electron, Scanning; Rats; Serine; Skin; Threonine; Tritium | 1974 |
Structure and specific binding of trypsin: comparison of inhibited derivatives and a model for substrate binding.
Topics: Amidines; Animals; Arginine; Aspartic Acid; Cattle; Glutamine; Histidine; Isoflurophate; Lysine; Models, Structural; Protein Binding; Protein Conformation; Trypsin; Trypsin Inhibitors; X-Ray Diffraction | 1974 |
The effect of monosodium glutamate on the early biochemical and behavioral development of the rat.
Topics: Amino Acids; Animals; Animals, Newborn; Aspartic Acid; Avoidance Learning; Behavior, Animal; Body Weight; Brain Chemistry; Discrimination Learning; Glutamates; Glutathione; Histidine; Liver; Motor Activity; Rats; Taurine; Urea; Visual Perception | 1974 |
Effect of concentrations of ammonium molybdate, diammonium hydrogen phosphate, formaldehyde, and minerals in mixture on the synthesis of amino acids.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Chromatography, Paper; Colorimetry; Cysteine; Formaldehyde; Glycine; Histidine; Minerals; Molybdenum; Organophosphorus Compounds; Quaternary Ammonium Compounds; Sterilization; Sunlight; Tyrosine | 1974 |
Specificity of amino acid transport in Trypanosoma equiperdum.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Binding Sites; Biological Transport; Carbon Radioisotopes; Culture Media; Cysteine; Diffusion; Glucose; Glutamates; Histidine; Lysine; Phenylalanine; Stimulation, Chemical; Trypanosoma | 1974 |
Silver ion inhibition of serine proteases: crystallographic study of silver-trypsin.
Topics: Aspartic Acid; Binding Sites; Histidine; Isoflurophate; Kinetics; Protein Binding; Protein Conformation; Silver; Trypsin; Trypsin Inhibitors; X-Ray Diffraction | 1974 |
A unique histidine-rich polypeptide from the malaria parasite, Plasmodium lophurae.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chromatography, Gel; Cytoplasmic Granules; Ducks; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Glutamates; Guanidines; Histidine; Hydrogen-Ion Concentration; Malaria; Microscopy, Electron; Peptides; Pigments, Biological; Plasmodium; Proline; Solubility | 1974 |
Conformation of lysozyme derivatives modified at two carboxyl groups.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Binding Sites; Carbodiimides; Chromatography, Ion Exchange; Circular Dichroism; Electrophoresis, Disc; Electrophoresis, Polyacrylamide Gel; Electrophoresis, Starch Gel; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Methylation; Micrococcus; Muramidase; Optical Rotatory Dispersion; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet; Trypsin | 1974 |
Free amino acids in developing rat retina.
Topics: Aging; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Chromatography, Ion Exchange; Glutamates; Glutamine; Glycine; Histidine; Methionine; Ornithine; Proline; Rats; Retina; Taurine; Time Factors; Tyrosine | 1974 |
High resolution nuclear magnetic resonance studies of the active site of chymotrypsin. I. The hydrogen bonded protons of the "charge relay" system.
Topics: Aspartic Acid; Binding Sites; Chymotrypsin; Chymotrypsinogen; Deuterium; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Serine | 1974 |
High resolution nuclear magnetic resonance studies of the active site of chymotrypsin. II. Polarization of histidine 57 by substrate analogues and competitive inhibitors.
Topics: Aspartic Acid; Binding Sites; Boric Acids; Boronic Acids; Carboxylic Acids; Chymotrypsin; Chymotrypsinogen; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Subtilisins; Trypsin Inhibitors | 1974 |
The distribution of amino acids, Na+ and K+ from surface to centre in incubated slices of mouse brain.
Topics: Adenosine Triphosphate; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Biological Transport; Biological Transport, Active; Brain; Carbon Radioisotopes; Glutamates; Glycine; Histidine; In Vitro Techniques; Inulin; Kinetics; Leucine; Lysine; Male; Mice; Potassium; Sodium; Time Factors; Urea | 1974 |
The effect of amino acids on the intestinal absorption of immunoglobulins in the neonatal rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carbon Radioisotopes; Cattle; Chromatography, Ion Exchange; Histidine; Ileum; Immunoglobulin G; Immunoglobulins; Intestinal Absorption; Iodine Radioisotopes; Leucine; Lysine; Methionine; Rats | 1974 |
Bovine pepsinogen and pepsin. I. Isolation, purification, and some properties of the pepsinogen.
Topics: Abomasum; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Electrophoresis, Disc; Enzyme Precursors; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Molecular Weight; Pepsin A; Proline; Swine; Tryptophan; Ultracentrifugation | 1968 |
Effect of amino acids and purine bases on thiamine synthesis by Escherichia coli.
Topics: Adenine; Amino Acids; Aspartic Acid; Culture Media; Cystine; Cytosine; Escherichia coli; Glutamates; Glycine; Guanine; Histidine; Hypoxanthines; Inositol; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Purines; Serine; Thiamine; Thiazoles; Threonine; Thymine; Tyrosine; Uracil; Valine | 1968 |
Suppressor selectrion for amino acid replacements expected on the basis of the genetic code.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bacterial Proteins; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Histidine; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Nucleotides; Phenylalanine; RNA, Messenger; Serine; Suppression, Genetic; Threonine; Tyrosine; Valine | 1967 |
Effect of hypermethylation on the functional properties of transfer ribonucleic acid.
Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Cysteine; Escherichia coli; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Methylation; RNA, Bacterial; RNA, Transfer | 1969 |
On the chemical structure of antigens and antibodies bound to fluorescent dyes. I. Structure of the antihuman gamma-globulin of the goat bound to the fluorochrome lissamine rhodamine B.
Topics: Amino Acids; Animals; Antibodies, Anti-Idiotypic; Antigens; Arginine; Aspartic Acid; Chromatography, Paper; Chymotrypsin; Electrophoresis; Fluorescent Dyes; Fluorometry; Goats; Histidine; Lysine; Oxidation-Reduction; Pepsin A; Protein Binding; Serine; Sulfides; Trypsin; Tryptophan; Tyrosine | 1966 |
Two mutations in the first gene of the histidine operon of Salmonella typhimurium affecting control.
Topics: Amino Acids; Aspartic Acid; Chromosome Mapping; Culture Media; Drug Resistance, Microbial; Enzyme Repression; Genes; Genetics, Microbial; Histidine; Microbial Sensitivity Tests; Models, Theoretical; Molecular Biology; Mutation; Operon; Paper; Phosphotransferases; Recombination, Genetic; Salmonella typhimurium; Spectrophotometry; Transduction, Genetic; Triazoles | 1971 |
Uptake of amino acids by actidione-treated yeast cells. I. Specificity of carriers.
Topics: Amino Acids; Arginine; Aspartic Acid; Binding Sites; Biological Transport; Carrier Proteins; Cell Membrane; Cycloheximide; Cysteine; Glutamates; Glycine; Histidine; Kinetics; Leucine; Lysine; Methionine; Proline; Protein Biosynthesis; Saccharomyces; Saccharomyces cerevisiae | 1971 |
Catabolic repression of bacterial sporulation.
Topics: Alanine; Ammonium Chloride; Aspartic Acid; Bacillus subtilis; Caseins; Citrates; Culture Media; Enzyme Repression; Glucose; Glutamates; Glycerol; Histidine; In Vitro Techniques; Lactates; Malates; Peptide Hydrolases; Ribose; Spores | 1965 |
"Dysgonic" strains of mycobacterium tuberculosis on Ogawa's egg medium isolated as pathogens from patients suffering from lung tuberculosis. II. Growth-inhibitory effects of D-asparagine, D-aspartic acid, Dl-serine, or L-serine against "dysgonic".
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Culture Media; Depression, Chemical; Glutamine; Histidine; Humans; Leucine; Mycobacterium tuberculosis; Proline; Serine; Tuberculosis, Pulmonary; Valine | 1967 |
[Glycopeptides of immunoglobulins, Microheterogeneity of the oligosaccharide chains of an immunoglobulin M from Waldenstrom's disease].
Topics: Amino Acid Sequence; Aspartic Acid; Autoanalysis; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Fucose; Galactose; Glucosamine; Glutamates; Histidine; Humans; Immunoglobulin M; Immunoglobulins; Lysine; Mannose; Neuraminic Acids; Oligosaccharides; Papain; Peptides; Proline; Serine; Threonine; Tyrosine; Valine; Waldenstrom Macroglobulinemia | 1970 |
The nutritive effect in man of non-essential amino acids infused intravenously (together with the essential ones). II. Different patterns of amino acids and different levels of nitrogen supply.
Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Female; Glycine; Histidine; Humans; Injections, Intravenous; Middle Aged; Nitrogen; Parenteral Nutrition; Proline; Time Factors; Urea | 1970 |
Interpretation of protein titration curves. Application to lysozyme.
Topics: Aspartic Acid; Binding Sites; Chemical Phenomena; Chemistry; Computers; Glutamates; Guanidines; Histidine; Hydrogen-Ion Concentration; Mathematics; Methods; Muramidase; Osmolar Concentration; Potassium Chloride; Protein Binding; Protein Conformation; Protein Denaturation; Protons; Thermodynamics | 1972 |
Amino acid patterns in the blood plasma of the young bovine.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Cystine; Female; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1972 |
The active center of aspartate transaminase. A fluorine-19 nuclear magnetic resonance study of the anion binding site.
Topics: Animals; Apoproteins; Aspartate Aminotransferases; Aspartic Acid; Binding Sites; Binding, Competitive; Borohydrides; Chlorides; Fluorine; Fluoroacetates; Histidine; Hydrogen-Ion Concentration; Light; Magnetic Resonance Spectroscopy; Mathematics; Methylation; Models, Structural; Myocardium; Oxidation-Reduction; Protein Conformation; Pyridoxal Phosphate; Radiation Effects; Schiff Bases; Succinates; Swine | 1972 |
Gluconeogenesis and amino acid metabolism. I. Comparison of various precursors for hepatic gluconeogenesis in vivo.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood Glucose; Carbon Isotopes; Cattle; Gluconeogenesis; Glucose Oxidase; Glutamate Dehydrogenase; Glutamates; Glycerol; Glycine; Hexokinase; Histidine; Kinetics; L-Lactate Dehydrogenase; Liver; Male; Rabbits; Rats; Serine; Swine | 1972 |
On the role of hydrogen-bonding system in the catalysis by serine proteases.
Topics: Aspartic Acid; Catalysis; Endopeptidases; Histidine; Models, Chemical; Serine | 1972 |
Effect of excess levels of individual amino acids on growth of rats fed casein diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Cystine; Depression, Chemical; Dietary Proteins; DNA; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Organ Size; Phenylalanine; Proline; Proteins; Rats; RNA; Serine; Stereoisomerism; Stimulation, Chemical; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
The protein and lipid composition of arterial elastin and its relationship to lipid accumulation in the atherosclerotic plaque.
Topics: Adolescent; Adult; Aged; Aorta; Arginine; Arteriosclerosis; Aspartic Acid; Cholesterol; Elastin; Esters; Female; Glutamates; Histidine; Humans; Lipids; Lung; Lysine; Male; Middle Aged; Phospholipids; Proteins; Serine; Threonine; Triglycerides; Tritium | 1971 |
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; Female; Gestational Age; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Paramagnetic metal ions as protectors of selected regions of protein molecules from photodynamic action.
Topics: Amino Acids; Animals; Aspartic Acid; Binding Sites; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Cobalt; Copper; Drug Stability; Glutamates; Guanidines; Histidine; Hydrogen-Ion Concentration; Kynurenine; Light; Methionine; Micrococcus; Muramidase; Oxidation-Reduction; Pancreas; Photochemistry; Protein Denaturation; Radiation Effects; Ribonucleases; Spectrophotometry; Sulfoxides; Temperature; Time Factors; Trypsin; Tryptophan; Tyrosine; Ultraviolet Rays; Zinc | 1971 |
Crystallographic analysis of the interaction of cuypric ion with ribonuclease S.
Topics: Acetates; Amino Alcohols; Animals; Arginine; Aspartic Acid; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Copper; Cytosine Nucleotides; Dinitrophenols; Glutamates; Histidine; Hydrogen-Ion Concentration; Lysine; Macromolecular Substances; Mathematics; Quaternary Ammonium Compounds; Ribonucleases; Serine; Sulfates; Temperature; X-Ray Diffraction | 1971 |
Active transport of glutamate in Streptomyces hydrogenans. I. Studies on uptake and pool size, and their interrelationship.
Topics: Aminoisobutyric Acids; Arginine; Asparagine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Cold Temperature; Culture Media; Dinitrophenols; Glutamate Dehydrogenase; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Mathematics; Methionine; Osmosis; Phenylalanine; Protein Biosynthesis; Stereoisomerism; Streptomyces; Temperature; Tyrosine | 1971 |
Comparison of amino acid concentrations between plasma and erythrocytes. Studies in normal human subjects and those with metabolic disorders.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Arginine; Aspartic Acid; Biological Transport; Child; Chromatography, Ion Exchange; Cystine; Erythrocytes; Glutamates; Glutathione; Glycine; Histidine; Homocystine; Homocystinuria; Humans; Infant; Maple Syrup Urine Disease; Methionine; Ornithine; Phenylketonurias; Plasma; Renal Tubular Transport, Inborn Errors; Serine; Spectrophotometry; Threonine; Tyrosine | 1971 |
Acidic and basic amino acid transport systems of Penicillium chrysogenum.
Topics: Adipates; Aminobutyrates; Arginine; Aspartic Acid; Biological Transport; Carbon Isotopes; Chromatography, Paper; Cycloheximide; Feedback; Glutamates; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Membrane Transport Proteins; Methionine; Ornithine; Osmolar Concentration; Penicillium; Phenylalanine; Proline; Sodium Chloride; Temperature | 1971 |
The effect of dietary fluoride on plasma free amino acid concentrations in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Diet; Feeding Behavior; Female; Fluorides; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Protein methylation.
Topics: Actins; Amino Acids; Animals; Arginine; Aspartic Acid; Autoanalysis; Carboxylic Acids; Cats; Cattle; Cell Wall; Chromatography, Paper; Cytochromes; Flagella; Glutamates; Histidine; Histones; Humans; Lysine; Methylation; Methyltransferases; Myosins; Ornithine; Ovalbumin; Proteins; Rabbits; Rats; Ribosomes; S-Adenosylmethionine | 1971 |
Effect of specific amino acids on in vitro protein synthesizing system from rats.
Topics: Amino Acids; Aminoacylation; Animals; Aspartic Acid; Carbon Isotopes; Culture Techniques; Female; Histidine; Isoleucine; Male; Methionine; Nutrition Disorders; Peptide Biosynthesis; Phenylalanine; Protein Biosynthesis; Rats; Valine | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
[Dissociation of S- and P-variants of Bacillus brevis var. G.-B. on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Mutation; Nitrogen; Ornithine; Phenylalanine; Serine; Stimulation, Chemical; Threonine; Time Factors; Tryptophan; Valine | 1971 |
The effect of diethyl pyrocarbonate on the transfer RNA of bovine muscle.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Aspartic Acid; Carbon Isotopes; Carbonates; Cattle; Chemical Phenomena; Chemistry; Chromatography; Chromatography, DEAE-Cellulose; Diaphragm; Histidine; Lens, Crystalline; Leucine; Liver; Lysine; Methionine; Muscles; Phenylalanine; Rats; RNA, Transfer; Serine; Tyrosine; Valine | 1971 |
Purification and the peptide nature of decapacitation factor.
Topics: Amides; Animals; Arginine; Aspartic Acid; Carboxypeptidases; Cattle; Cellulose; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Contraceptive Agents; Histidine; Hydrolysis; Male; Methods; Peptides; Pronase; Resins, Plant; Semen; Trypsin; Ultracentrifugation | 1971 |
[Antineoplastic effect and chemical structure of protamines of various origin].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Depression, Chemical; Fishes; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Leukemia, Experimental; Lysine; Methionine; Mice; Proline; Protamines; Sarcoma 37; Serine; Threonine | 1971 |
Amino acid fermentation by Fusobacterium nucleatum.
Topics: Amino Acids; Aspartic Acid; Cysteine; Fermentation; Fusobacterium; Gingiva; Glutamates; Glutamine; Histidine; Humans; Lysine; Methionine; Mouth; Serine; Threonine | 1968 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Isoaccepting transfer RNA's of L-M cells in culture and after tumor induction in C3H mice.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cell Line; Chromatography; Connective Tissue; Culture Media; Culture Techniques; Female; Fibrosarcoma; Glycine; Histidine; Isoleucine; Leucine; Ligases; Lysine; Male; Methionine; Mice; Phenylalanine; Proline; RNA, Transfer; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Citrulline; Cystine; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Leukemia, Lymphoid; Lysine; Methionine; Ornithine; Phenylalanine; Prednisolone; Proline; Serine; Threonine; Triethylenemelamine; Tyrosine; Valine; Vincristine | 1971 |
Aggregated states of chromatophore membrane protein from Rhodopseudomonas spheroides.
Topics: Aspartic Acid; Bacterial Chromatophores; Bacterial Proteins; Buffers; Chromatography, Thin Layer; Detergents; Histidine; Membranes; Rhodobacter sphaeroides; Rhodopseudomonas; Ultracentrifugation; Urea | 1971 |
Imidazolylacetolphosphate:L-glutamate aminotransferase. Composition and substructure.
Topics: Alanine; Ammonia; Arginine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Electrophoresis; Genes; Glycine; Histidine; Leucine; Methionine; Molecular Biology; Molecular Weight; Peptides; Phenylalanine; Proline; Salmonella typhimurium; Serine; Threonine; Transaminases; Tyrosine; Valine | 1967 |
Suggested interpretation of diminished Bohr effect in haemoglobin Hiroshima.
Topics: Amino Acid Sequence; Aspartic Acid; Hemoglobins, Abnormal; Histidine; Hydrogen-Ion Concentration; Models, Chemical; Oxygen | 1969 |
Isolation of radioactive amino acids and derivatives from peripheral nerve.
Topics: Amino Acids; Aminobutyrates; Animals; Anura; Aspartic Acid; Autoradiography; Brain; Carbon Isotopes; Chromatography, Paper; Electrophoresis; Glutamates; Histidine; Injections, Intraperitoneal; Liver; Lysine; Peripheral Nerves; Sciatic Nerve; Time Factors | 1969 |
Studies on the mechanism of action and the structure of the electrophilic center of histidine ammonia lyase.
Topics: Alkanes; Amino Acids; Aminobutyrates; Ammonia; Aspartic Acid; Binding Sites; Boron Compounds; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Chromatography, DEAE-Cellulose; Electrophoresis; Glycine; Histidine; Hydroxybutyrates; Lyases; Methods; Proteus; Quaternary Ammonium Compounds; Tritium; Ultracentrifugation; Vibration | 1969 |
Changes in free amino acids of tomato fruit under pathogenesis.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Fruit; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Plant Diseases; Serine; Threonine; Tyrosine; Valine | 1969 |
Structure of crystalline alpha-chymotrypsin. 3. Crystallographic studies of substrates and inhibitors bound to the active site of alpha-chymotrypsin.
Topics: Arginine; Aspartic Acid; Binding Sites; Chymotrypsin; Histidine; Indoles; Lysine; Molecular Biology; Peptides; Protein Binding; Serine; Toluene; Trypsin; Tryptophan; X-Ray Diffraction | 1969 |
Sensitized photooxidation of histidine and its derivatives. Products and mechanism of the reaction.
Topics: Aspartic Acid; Benzene Derivatives; Benzoates; Chromatography, Ion Exchange; Electrophoresis; Histidine; Infrared Rays; Light; Magnetic Resonance Spectroscopy; Manometry; Methylation; Methylene Blue; Oxidation-Reduction; Oxygen Consumption; Peroxides; Radiation Effects; Riboflavin; Rose Bengal; Spectrophotometry; Spectrum Analysis; Time Factors; Ultraviolet Rays; Urea | 1969 |
[Chemical and physico-chemical properties of placental protein with antineoplastic effect].
Topics: Alanine; Amino Acids; Ammonia; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Electrophoresis; Female; Glutamates; Glycine; Histidine; Humans; Leucine; Lysine; Phenylalanine; Placenta; Proline; Proteins; Serine; Threonine; Tyrosine; Valine | 1969 |
Distribution and uptake of amino acids in various regions of the cat brain in vitro.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Aspartic Acid; Biological Transport, Active; Brain; Brain Chemistry; Carbon Isotopes; Cats; Extracellular Space; Histidine; In Vitro Techniques; Inulin; Nerve Tissue Proteins; Taurine; Water | 1969 |
Study on the amino acid composition in the cornea of hypophysectomized rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cornea; Cystine; Electrophoresis; Glutamates; Glycine; Growth Hormone; Histidine; Hypophysectomy; Leucine; Lysine; Methionine; Phenylalanine; Pituitary Gland; Rats; Serine; Threonine; Tyrosine | 1969 |
Amino acid interactions in chick nutrition. 1. The interrelationship between lysine and arginine.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Aspartic Acid; Body Weight; Chickens; Cobalt; Copper; Electrolytes; Female; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Manganese; Molybdenum; Nutritional Requirements; Phenylalanine; Selenium; Threonine; Tyrosine; Vitamins; Zinc | 1970 |
[Study of chemical composition and antineoplastic effect of protamines isolated from the milt of sturgeon fishes].
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Thin Layer; Depression, Chemical; Electrophoresis; Fishes; Glutamates; Glycine; Histidine; Leucine; Lysine; Male; Methionine; Mice; Molecular Weight; Neoplasms, Experimental; Nucleic Acids; Proline; Protamines; Sarcoma 37; Serine; Spectrum Analysis; Sulfates; Threonine; Ultraviolet Rays | 1970 |
[Biosynthesis of gramicidin C on synthetic media with amino acids as the only N source].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Tyrothricin; Valine | 1970 |
Changes in the concentration of specific amino acids in the serum of experimentally malnourished pigs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Dietary Proteins; Female; Gluconeogenesis; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Protein Deficiency; Serine; Swine; Threonine; Tyrosine; Valine | 1970 |
Two haemoglobins Q, alpha-74 (EF3) and alpha-75 (EF4) aspartic acid to histidine.
Topics: Adult; Amino Acid Sequence; Aspartic Acid; Child; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Electrophoresis; Female; Genes; Hemoglobins, Abnormal; Histidine; Humans; Mutation; Peptides; Thalassemia | 1970 |
Metabolism of amino acids in incubated slices of mouse brain.
Topics: Alanine; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Brain; Carbon Isotopes; Centrifugation; Cerebellum; Cerebral Cortex; Chromatography, Paper; Glucose; Histidine; In Vitro Techniques; Leucine; Lysine; Medulla Oblongata; Mesencephalon; Mice; Oxygen Consumption; Phenylalanine; Pons; Proline; Valine | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
Primary structure of two COOH-terminal hexapeptides from rabbit muscle aldolase: a difference in the structure of the alpha and beta subunits.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Aspartic Acid; Carboxypeptidases; Chromatography, Ion Exchange; Chymotrypsin; Fructose-Bisphosphate Aldolase; Histidine; Muscles; Rabbits; Trypsin; Tyrosine | 1970 |
The effect on the nitrogen balance of the ratio essential-non-essential amino acids in intravenously infused solutions.
Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Blood Urea Nitrogen; Female; Glycine; Histidine; Humans; Infusions, Parenteral; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Proline; Threonine; Tryptophan; Valine | 1970 |
[Effect of amino acids on the growth of Streptococcus lactis and biosynthesis of nisin].
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Asparagine; Aspartic Acid; Culture Media; Cysteine; Cystine; Depression, Chemical; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Stimulation, Chemical; Streptococcus; Threonine; Tryptophan; Valine | 1970 |
An TpVI hemoglobin variant in Manitoba.
Topics: Aged; Amino Acids; Aspartic Acid; Blood Protein Electrophoresis; Chromatography, Paper; Electrophoresis, Paper; Hemoglobins, Abnormal; Histidine; Humans; Hydrolysis; Jews; Male; Manitoba; Peptides; Trypsin | 1970 |
Urinary amino acid excretion in patients with scleroderma.
Topics: Arginine; Aspartic Acid; Chelating Agents; Female; Glutamates; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Renal Aminoacidurias; Scleroderma, Systemic; Threonine; Tyrosine; Valine | 1971 |
Histones of polytene and nonpolytene nuclei of Drosophila melanogaster.
Topics: Animals; Aspartic Acid; Birds; Cattle; Cell Nucleus; Drosophila; Echinodermata; Electrophoresis; Equipment and Supplies; Histidine; Histones; Isoleucine; Larva; Lysine; Methods; Molecular Weight; Salivary Glands; Serine; Thymus Gland; Valine | 1971 |
The nutritive effect in man of non-essential amino acids infused intravenously (together with the essential ones). IV. Aspartic acid.
Topics: Adult; Amino Acids; Arginine; Aspartic Acid; Female; Histidine; Humans; Injections, Intravenous; Nitrogen; Time Factors | 1971 |
Purification and chemical studies of a toxin from the venom of Lapemis hardwickii (Hardwick's sea snake).
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Electrophoresis; Histidine; Hydrogen-Ion Concentration; Isoelectric Focusing; Mice; Molecular Weight; Nitrobenzenes; Pyrrolidinones; Snakes; Spectrum Analysis; Sulfenic Acids; Sulfhydryl Compounds; Toxins, Biological; Tryptophan; Ultracentrifugation; Venoms | 1971 |
Nutrient media for plant-parasitic nematodes. II. Amino acid requirements of Aphelenchoides sp.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Fungi; Germ-Free Life; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Nematoda; Nutritional Requirements; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
[Dissociation of R- and P plus-variants of Bacillus brevis var. G.-B. during growth on a synthetic medium with amino acids as the only source of nitrogen].
Topics: Alanine; Amino Acids; Aspartic Acid; Bacillus; Culture Media; Cysteine; Genetic Variation; Glycine; Histidine; Leucine; Lysine; Nitrogen; Ornithine; Phenylalanine; Serine; Threonine; Tryptophan; Valine | 1971 |
The entry of amino acids into the myocardium of the growing rat in vivo.
Topics: Amino Acids; Animals; Aspartic Acid; Diffusion; Glycine; Heart; Histidine; Isoleucine; Leucine; Lysine; Methionine; Myocardium; Phenylalanine; Protein Binding; Protein Biosynthesis; Rats; Serine; Taurine; Tryptophan; Tyrosine; Valine | 1971 |
Binding of N-(2-bromo ethyl)-N-ethyl-N 1 -naphthylmethylamine HBr (SY28) to the proteins of guinea-pig vas deferens.
Topics: Animals; Arginine; Aspartic Acid; Autoradiography; Binding Sites; Carbon Isotopes; Chromatography, Gel; Chromatography, Paper; Ethylamines; Guinea Pigs; Histidine; In Vitro Techniques; Male; Naphthalenes; Protein Binding; Serine; Sympatholytics; Vas Deferens | 1971 |
The uptake of various amino acids by the mouse brain in vivo.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Brain; Glycine; Histidine; Isoleucine; Methionine; Mice; Serine; Threonine; Time Factors; Tryptophan; Valine | 1971 |
Essential amino acids in the culture of Leishmania tarentolae.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Glucose; Glutamates; Glycine; Histidine; Leishmania; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Molecular transport. I. In vivo studies of transport mutants of Neurospora crassa with altered amino acid competition patterns.
Topics: Alanine; Arginine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Crosses, Genetic; Genetics, Microbial; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Serine; Stereoisomerism; Threonine; Tyrosine; Valine | 1971 |
[Biosphere products of Sinapis alba. I. Rhizosphere products].
Topics: Alanine; Amino Acids; Aminobutyrates; Arabinose; Arginine; Aspartic Acid; Citrates; Cysteine; Glucose; Glutamates; Glycine; Hexoses; Histidine; Keto Acids; Leucine; Mannose; Mustard Plant; Oxalates; Pentoses; Plants, Medicinal; Proline; Ribose; Threonine; Valine; Xylose | 1967 |
[Structure analysis of hemoglobin Köln].
Topics: Amino Acids; Arginine; Aspartic Acid; Chromatography, Gel; Chromatography, Paper; Glutamates; Hemoglobins, Abnormal; Histidine; Humans; Leucine; Methionine; Methods; Phenylalanine; Proline; Valine | 1967 |
[Hyperaminoaciduria in children suffering from progressive muscular dystrophy].
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Aspartic Acid; Child; Child, Preschool; Creatine; Creatinine; Female; Glutamates; Histidine; Humans; Leucine; Lysine; Male; Methionine; Muscular Dystrophies; Nitrogen; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
[Quantitative paper chromatography amino acid determination. Stanardization of the procedure and method of testing of new paper types].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glutamates; Glycine; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Methods; Paper; Phenylalanine; Serine; Spectrum Analysis; Sulfones; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Studies on progressive muscular dystrophy. IV. Effects of original amino acids mixture on progressive muscular dystrophy.
Topics: Adenosine Triphosphate; Adolescent; Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Blood Proteins; Child; Deficiency Diseases; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Muscles; Muscular Dystrophies; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Haemoglobin J Sardegna: alpha 50(CD 8) histidine -aspartic acid.
Topics: Amino Acid Sequence; Aspartic Acid; Hemoglobins, Abnormal; Histidine; Humans; Italy | 1968 |
A practical quantitative gas chromatographic analysis of amino acids using the n-propyl n-acetyl esters.
Topics: Amino Acids; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Chromatography, Gas; Esters; Histidine; Methods; Ornithine | 1968 |
[Effect of novobiocin on the synthesis of free amino acids and volatile organic acids of its own producer, Act. spheroides strain 35, and its inactive mutant].
Topics: Acetates; Acids; Actinomyces; Alanine; Amino Acids; Aspartic Acid; Butyrates; Formates; Genetics, Microbial; Glutamates; Histidine; Leucine; Methionine; Mutation; Novobiocin; Propionates | 1968 |
Analysis of carboxymethylated residues in proteins by an isotopic method, and its application to the bromoacetate-ribonuclease reaction.
Topics: Acetates; Amino Acids; Aspartic Acid; Autoanalysis; Carbon Isotopes; Glycolates; Histidine; Homocysteine; Hydrogen-Ion Concentration; Indicators and Reagents; Iodoacetates; Lysine; Methionine; Methods; Proteins; Ribonucleases; Sulfonic Acids; Time Factors | 1968 |
High-resolution nuclear magnetic resonance spectra of selectively deuterated staphylococcal nuclease.
Topics: Amino Acids; Asparagine; Aspartic Acid; Calcium; Deoxyribonucleases; Deuterium; Glutamates; Glutamine; Histidine; Magnetic Resonance Spectroscopy; Methionine; Nucleotides; Ribonucleases; Staphylococcus; Tryptophan; Tyrosine | 1968 |
A study of 2,4,6-trinitrobenzenesulfonic acid for automated amino acid chromatography.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Autoanalysis; Chromatography; Cystine; Glycine; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Isoleucine; Leucine; Lysine; Methionine; Methods; Nitrobenzenes; Phenylalanine; Proline; Serine; Spectrophotometry; Sulfonic Acids; Temperature; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1968 |
Trace metal requirements for malformin biosynthesis.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Aspergillus; Chromium; Cobalt; Copper; Cysteine; Glutamine; Glycine; Histidine; Iron; Isoleucine; Leucine; Lysine; Manganese; Metals; Molybdenum; Peptide Biosynthesis; Phenylalanine; Plant Growth Regulators; Proline; Serine; Trace Elements; Tryptophan; Tyrosine; Valine; Zinc | 1968 |
[Examination of beta-l-aspartyl-l-histidine as a precursor for carnosine and anserine (Studies on heart. X)].
Topics: Animals; Aspartic Acid; Carbon Isotopes; Dipeptides; Heart; Histidine; Male; Rats | 1968 |
[On deamination of amino acids by plague microorganism].
Topics: Amino Acids; Ammonia; Aspartic Acid; Cell-Free System; Depression, Chemical; Genetics, Microbial; Guanidines; Histidine; Hydroxylamines; Isoniazid; Keto Acids; Ornithine; Species Specificity; Vaccines; Yersinia pestis | 1968 |
Calf and pea histone IV. I. Amino acid compositions and the identical COOH-terminal 19-residue sequence.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Evolution; Bromine; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Plants; Proline; Serine; Threonine; Trypsin; Tyrosine; Valine | 1968 |
The structure of goat hemoglobins. 3. Hemoglobin D, a beta chain variant with one apparet amino acid substitution (21 Asp--His).
Topics: Amino Acids; Animals; Aspartic Acid; Chromatography, Ion Exchange; Dextrans; Electrophoresis; Genes; Genetic Variation; Goats; Hemoglobins; Heterozygote; Histidine; Molecular Biology; Mutation; Peptides; Trypsin | 1968 |
Oxygen-equilibrium characteristics of abnormal hemoglobin Hiroshima (alpha-2 beta-2 143 Asp).
Topics: Aspartic Acid; Chemical Phenomena; Chemistry; Electrophoresis; Genetic Variation; Heme; Hemoglobins; Hemoglobins, Abnormal; Hemolysis; Histidine; Humans; Hydrogen-Ion Concentration; Japan; Molecular Biology; Oxygen; Peptides; Spectrophotometry | 1968 |
Nitrogen, energy and vitamin nutrition of Rhizobium japonicum.
Topics: Ammonium Chloride; Aspartic Acid; Biotin; Carbon; Culture Media; Glutamates; Histidine; Proline; Protein Hydrolysates; Rhizobium; Vitamins | 1968 |
States of amino acid residues in proteins. XVI. Naphthoquinones with two sulfonic groups as a reagent for discrimation of amino groups in proteins.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chymotrypsin; Colorimetry; Freezing; Glycine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Indicators and Reagents; Insulin; Lysine; Muramidase; Naphthoquinones; Proline; Proteins; Ribonucleases; Serine; Spectrophotometry; Sulfonic Acids; Tryptophan; Tyrosine | 1968 |
The uptake of [3H]GABA by slices of rat cerebral cortex.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Centrifugation; Cerebral Cortex; Chromatography, Ion Exchange; Glycine; Guanidines; Histidine; In Vitro Techniques; Kinetics; Male; Oxygen; Propionates; Rats; Sodium; Temperature; Tritium | 1968 |
Transferrin DChi: the amino acid substitution.
Topics: Alanine; Amino Acid Sequence; Arginine; Aspartic Acid; Glutamates; Histidine; Humans; Lysine; Peptides; Proline; Serine; Transferrin; Trypsin; Valine | 1968 |
Influence of protein digestion on plasma amino acid levels in sheep.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Digestion; Glutamates; Glycine; Histidine; Intestinal Mucosa; Isoleucine; Leucine; Lysine; Male; Phenylalanine; Proline; Sheep; Tyrosine; Valine | 1968 |
Side reactions in the synthesis of peptides containing the aspartyglycyl sequence.
Topics: Aspartic Acid; Chemical Phenomena; Chemistry; Glycine; Heterocyclic Compounds; Histidine; Imides; Peptides; Phenylalanine; Serine; Succinates; Threonine | 1968 |
[Differentiation of Shigella on the basis of the activity of various enzymes of amino acid metabolism].
Topics: Aspartic Acid; Carboxy-Lyases; Culture Media; Electrophoresis; Glutamates; Histidine; Leucine; Ornithine; Phenylalanine; Serine; Shigella; Transaminases | 1968 |
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Histidine; Histocytochemistry; Humans; Isoleucine; Leucine; Lysine; Methods; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Phenylalanine; Serine; Threonine; Time Factors; Tyrosine; Valine | 1968 |
Structure of crystalline -chymotrypsin. II. A preliminary report including a hypothesis for the activation mechanism.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Biochemical Phenomena; Biochemistry; Chymotrypsin; Crystallography; Enzyme Activation; Enzyme Precursors; Histidine; Isoleucine; Mercury; Methionine; Models, Structural; Platinum; Serine; Trypsin | 1968 |
Role of a buried acid group in the mechanism of action of chymotrypsin.
Topics: Amino Acid Sequence; Aspartic Acid; Bacteria; Binding Sites; Chymotrypsin; Endopeptidases; Histidine; Serine | 1969 |
[Consumption of amino acids by strains of typhoid bacteria Salm. typhi abdominalis sensitive and resistant to antibiotics].
Topics: Amino Acids; Anti-Bacterial Agents; Aspartic Acid; Chloramphenicol; Chlortetracycline; Colistin; Depression, Chemical; Drug Resistance, Microbial; Glutamates; Histidine; Salmonella typhi; Streptomycin; Threonine | 1969 |
Circadian periodicity of blood amino acids in normal and adrenalectomized mice.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Circadian Rhythm; Cystine; Densitometry; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Mice; Serine; Threonine; Tryptophan; Tryptophan Oxygenase; Tyrosine; Valine | 1969 |
Urinary amino acid and peptide excretion patterns in patients with muscular dystrophy (Duchenne). A preliminary study with the autoanalyzer.
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Autoanalysis; Child; Child, Preschool; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Muscular Dystrophies; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1969 |
A new haemoglobin: Hb J Sardegna (alpha50 histidine--aspartic acid).
Topics: Anemia; Aspartic Acid; Child; Erythrocyte Count; Female; Genetics, Medical; Hemoglobinometry; Hemoglobins, Abnormal; Histidine; Humans; Italy | 1969 |
Fractionation on benzoylated DEAE-cellulose of tRNA from tobacco mosaic virus-infected tobacco leaves.
Topics: Alanine; Aspartic Acid; Chromatography; Histidine; Isoleucine; Leucine; Methionine; Nicotiana; Phenylalanine; Plants, Toxic; RNA, Transfer; RNA, Viral; Serine; Tobacco Mosaic Virus | 1969 |
[Studies on the amino acid composition of some African legumes].
Topics: Amino Acids; Arginine; Aspartic Acid; Canavanine; Chromatography; Cystine; Food Analysis; Glutamine; Glycine; Histidine; Hot Temperature; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants, Edible; Proline; Proteins; Serine; Threonine; Tryptophan; Tyrosine; Valine; Vegetables | 1969 |
Amino acid uptake and incorporation into macromolecules of peripheral nerves.
Topics: Amino Acids; Amphibians; Animals; Aspartic Acid; Brain; Carbon Isotopes; DNA; Glutamates; Histidine; Leucine; Lipid Metabolism; Liver; Lysine; Macromolecular Substances; Nerve Tissue Proteins; Peripheral Nerves; RNA; RNA, Transfer; Starvation; Tritium | 1969 |
Histones in early embryogenesis.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Echinodermata; Electrophoresis; Embryo, Nonmammalian; Fishes; Gels; Genetic Code; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
NMR-studies on the structure of the active site of pancreatic ribonuclease A.
Topics: Amino Acids; Animals; Aspartic Acid; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Deuterium; Histidine; Hydrogen-Ion Concentration; Imidazoles; Magnetic Resonance Spectroscopy; Pancreas; Protein Binding; Protons; Ribonucleases | 1969 |
Preferential binding of amino acids to isolated mucosal brush borders from hamster jejunum.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Benzoates; Binding Sites; Biological Transport, Active; Carbon Isotopes; Cricetinae; Epithelium; Glucosamine; Glucose; Histidine; Intestinal Mucosa; Jejunum; Potassium Chloride; Proline; Sodium Chloride; Tritium | 1969 |
Comparative biochemistry of deamination of L-amino acids in elasmobranch and teleost fish.
Topics: Amino Acids; Ammonia; Animals; Aspartic Acid; Brain; Fishes; Histidine; Kidney; Liver; Physiology, Comparative | 1965 |
The influence of amino-acid sequence on protein structure.
Topics: Amino Acid Sequence; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Glutamates; Hemoglobins; Histidine; Muramidase; Myoglobin; Proline; Proteins; Tobacco Mosaic Virus; Viral Proteins | 1965 |
Effect of acidic (dicarboxylic) alpha-amino acids on uptake of L-histidine by intestinal mucosa, testis, spleen and kidney in vitro: a comparison with effect in brain.
Topics: Adipates; Amino Acids; Animals; Aspartic Acid; Brain; Glutamates; Histidine; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Kidney; Male; Methionine; Rats; Spleen; Testis | 1965 |
Amino acids in seven species of cestodes.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cestoda; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Nitrogen; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Effect of amino acids on the nitrogenase system of Klebsiella pneumoniae.
Topics: Amino Acids; Aspartic Acid; Autoanalysis; Enzyme Induction; Glutamates; Histidine; Isoleucine; Klebsiella; Leucine; Nitrogen; Oxidoreductases; Quaternary Ammonium Compounds; Serine; Threonine | 1966 |
Nature of the free amino-acid pool in avian tissues.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Blood; Histidine; Leucine; Liver; Lysine; Newcastle Disease; Poultry; Valine | 1966 |
[Two dimension chromatography of ether soluble dinitrophenyl-amino acids and chromato-electrophoresis of hydracid-soluble DNP-amino acids on thin layers of powdered cellulose].
Topics: Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography, Thin Layer; Cysteine; Dinitrophenols; Electrophoresis; Glutamates; Glutamine; Histidine; Lysine | 1966 |
Nuclear histones and early embryogenesis of the chick.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Cell Division; Cell Nucleus; Chick Embryo; Electrophoresis; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
[The influence of certain humoral factors on the rate of food reactions in the fish].
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Citrates; Feeding Behavior; Fishes; Glucose; Histidine; Leucine; Tryptophan; Tyrosine; Valine | 1966 |
Free amino acids of human foetal and adult liver.
Topics: Adult; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Cystine; Female; Fetus; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1966 |
The recovery of amino acids from acid hydrolysates of whole urine from patients with thermal burns.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Burns; Creatine; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1967 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
Gluconeogenesis from amino acids in neonatal rat liver.
Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartate Aminotransferases; Aspartic Acid; Gluconeogenesis; Glutamates; Glycine; Histidine; In Vitro Techniques; Leucine; Liver; Liver Glycogen; Phenylalanine; Proline; Rats; Serine; Spectrophotometry; Threonine; Tyrosine; Valine | 1967 |
Regulation of glutamine synthetase. VI. Interactions of inhibitors for Bacillus licheniformis glutamine synthetase.
Topics: Acyltransferases; Adenine Nucleotides; Alanine; Ammonium Chloride; Asparagine; Aspartic Acid; Bacillus; Carbamates; Drug Antagonism; Drug Synergism; Feedback; Glutamates; Glutamine; Glycine; Histidine; Hydroxamic Acids; Isoleucine; Kinetics; Ligases | 1967 |
Effects of sonic irradiation on yeast.
Topics: Aspartic Acid; Carbon Isotopes; Cell Membrane Permeability; Histidine; Saccharomyces; Succinates; Temperature; Ultrasonics; Uridine; Viscosity | 1967 |
Hemoglobin Yakina. I. Clinical and biochemical studies.
Topics: Aspartic Acid; Female; Hemoglobins, Abnormal; Histidine; Humans; Polycythemia | 1967 |
Chromatographic analysis of free amino acids of gastric juice in patients with cancer and other stomach diseases.
Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Cystine; Duodenal Ulcer; Female; Gastric Juice; Glutamates; Histidine; Humans; Leucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Polyps; Stomach Diseases; Stomach Neoplasms; Stomach Ulcer; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
The influence of nitrogenous compounds on growth of Pythium species.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Cysteine; Fungi; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Nitrates; Nitrites; Nitrogen; Peptones; Quaternary Ammonium Compounds; Serine; Succinates; Threonine; Yeast, Dried | 1967 |
A common step in the intestinal absorption mechanisms of D- and L-methionine.
Topics: Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Chickens; Depression, Chemical; Epithelium; Female; Histidine; Intestinal Mucosa; Kinetics; Lysine; Methionine; Receptors, Drug | 1967 |
Effect of amino acids on zinc-65 incorporation by Ehrlich ascites tumor cells in vitro.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Female; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Lysine; Methionine; Mice; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Zinc; Zinc Isotopes | 1967 |
Charge state of His-57-Asp-102 couple in a transition state analogue-trypsin complex: a molecular orbital study.
Topics: Aspartic Acid; Binding Sites; Catalysis; Histidine; Models, Chemical; Protons; Structure-Activity Relationship; Trypsin | 1984 |
Human prostatic acid phosphatase: a histidine phosphatase.
Topics: Acid Phosphatase; Arginine; Aspartic Acid; Binding Sites; Chemical Phenomena; Chemistry; Glutamates; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Male; Phosphotransferases; Prostate | 1982 |
Hemoglobin I (alpha 16(A14) Lys replaced by Glu) and hemoglobin J Iran (beta 77(EF1) His replaced by Asp) discovered in Japanese.
Topics: Aspartic Acid; Female; Globins; Glutamates; Glutamic Acid; Hemoglobin J; Hemoglobins; Hemoglobins, Abnormal; Histidine; Humans; Japan; Lysine; Male; Middle Aged | 1982 |
Evidence for the identification of synaptic transmitters released by photoreceptors of the toad retina.
Topics: Animals; Aspartic Acid; Bufo marinus; Cadaverine; Cells, Cultured; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Histidine; Neurotransmitter Agents; Photoreceptor Cells; Putrescine; Retina; Synapses; Time Factors | 1983 |
Organization of alpha-globin genes and mRNA translation in subjects carrying haemoglobin Hasharon (alpha 47 Asp replaced by His) from the Ferrara Region (Northern Italy).
Topics: Aspartic Acid; DNA; DNA Restriction Enzymes; Genes; Globins; Hemoglobins, Abnormal; Histidine; Humans; Italy; Jews; Protein Biosynthesis | 1980 |
The pKa value of His 57-Asp 102 couple in the active site of bovine pancreatic beta-trypsin: a molecular orbital study.
Topics: Animals; Aspartic Acid; Binding Sites; Cattle; Histidine; Hydrogen Bonding; Models, Chemical; Pancreas; Protons; Quantum Theory; Trypsin | 1982 |
The toxicity of tritium: the effects of tritiated amino-acids on preimplanted mouse embryos.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Blastocyst; Female; Histidine; Lysine; Mice; Thymidine; Time Factors; Tritium | 1984 |
Chemical factors affecting the intestinal absorption of zinc in vitro and in vivo.
Topics: Animals; Anions; Aspartic Acid; Citrates; Citric Acid; Duodenum; Histidine; Hydrogen-Ion Concentration; Ileum; In Vitro Techniques; Intestinal Absorption; Isomerism; Ligands; Male; Picolinic Acids; Rats; Rats, Inbred Strains; Sulfates; Zinc; Zinc Sulfate | 1983 |
Defined medium for Aquaspirillum serpens VHL effective in batch and continuous culture.
Topics: Alanine; Ammonium Chloride; Aspartic Acid; Bacteria; Culture Media; Glutamates; Histidine | 1980 |
Analysis of the acid-base titration curve of hen lysozyme.
Topics: Animals; Aspartic Acid; Chickens; Glutamates; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Muramidase; Tyrosine | 1980 |
Effect of diet on the queuosine family of tRNAs of germ-free mice.
Topics: Animals; Anticodon; Asparagine; Aspartic Acid; Codon; Diet; Female; Germ-Free Life; Guanosine; Histidine; Male; Mice; Nucleoside Q; RNA, Transfer; Tyrosine | 1980 |
The localization of tRNA5Asn, tRNAHis, and tRNAAla genes from drosophila melanogaster by in situ hybridization to polytene salivary gland chromosomes.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Chromosome Mapping; DNA; Drosophila melanogaster; Genes; Histidine; Nucleic Acid Hybridization; RNA, Transfer | 1980 |
Role of Asp102 in the enzymatic reaction of bovine beta-trypsin. A molecular orbital study.
Topics: Animals; Aspartic Acid; Cattle; Energy Transfer; Histidine; Hydrogen Bonding; Models, Molecular; Serine; Thermodynamics; Trypsin | 1981 |
Interactions between Asp, His, Ser residues within models of the active site of serine proteases. A theoretical empirical study.
Topics: Aspartic Acid; Binding Sites; Chymotrypsin; Dipeptides; Endopeptidases; Histidine; Models, Molecular; Protein Conformation; Serine; Serine Endopeptidases; Structure-Activity Relationship; Subtilisins | 1982 |
Synthesis, conformation and reactivity towards p-nitrophenyl acetate of polypeptides incorporating aspartic acid, serine and histidine.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Chymotrypsin; Circular Dichroism; Histidine; Nitrophenols; Peptides; Protein Conformation; Serine; Spectrophotometry, Infrared; Structure-Activity Relationship; Subtilisins | 1982 |
The presence of a histidine-aspartic acid pair in the active site of 2-hydroxyacid dehydrogenases. X-ray refinement of cytoplasmic malate dehydrogenase.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Binding Sites; Histidine; Malate Dehydrogenase; Models, Molecular; Protein Conformation; X-Ray Diffraction | 1983 |
Oxidation of carbonyl hemoglobins by ferricyanide. Hemoglobins A, Osler (beta 145 Tyr replaced by Asp) and Zurich (beta 63 His replaced by Arg).
Topics: Arginine; Aspartic Acid; Carboxyhemoglobin; Ferricyanides; Hemoglobin A; Hemoglobins, Abnormal; Histidine; Humans; Oxidation-Reduction; Phytic Acid; Spectrophotometry; Tyrosine | 1982 |
Modification of aspartate before its condensation with dihydroxyacetone phosphate during quinolinic acid formation in Escherichia coli.
Topics: Aspartic Acid; Cell-Free System; Dihydroxyacetone Phosphate; Escherichia coli; Fructosediphosphates; Histidine; Mutation; NAD; Proline; Pyridines; Quinolinic Acids; Trioses | 1980 |
Proton nuclear magnetic resonance evidence for the absence of a stable hydrogen bond between the active site aspartate and histidine residues of native subtilisins and for its presence in thiolsubtilisins.
Topics: Aspartic Acid; Binding Sites; Dithionitrobenzoic Acid; Histidine; Hydrogen Bonding; Iodoacetamide; Magnetic Resonance Spectroscopy; Subtilisins | 1981 |
Direct determination of the protonation states of aspartic acid-102 and histidine-57 in the tetrahedral intermediate of the serine proteases: neutron structure of trypsin.
Topics: Aspartic Acid; Endopeptidases; Histidine; Hydrogen-Ion Concentration; Models, Molecular; Neutrons; Protein Conformation; Serine Endopeptidases; Trypsin; X-Ray Diffraction | 1981 |
Binding of porcine pancreatic phospholipase A2 to various micellar substrate analogues. Involvement of histidine-48 and aspartic acid-49 in the binding process.
Topics: Animals; Aspartic Acid; Binding Sites; Calcium; Histidine; Hydrogen-Ion Concentration; Kinetics; Micelles; Pancreas; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Protein Binding; Protein Conformation; Structure-Activity Relationship; Swine | 1981 |
Roles of histidine-194, aspartate-163, and a glycine-rich sequence of NAD(P)H:quinone oxidoreductase in the interaction with nicotinamide coenzymes.
Topics: Animals; Aspartic Acid; Base Sequence; Binding Sites; Consensus Sequence; DNA Primers; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NAD(P)H Dehydrogenase (Quinone); NADP; Oxidation-Reduction; Rats; Structure-Activity Relationship; Vitamin K | 1995 |
Functional alterations in adult and fetal hemoglobin Sassari Asp-alpha 126(H9)-->His. The role of alpha 1 alpha 2 contact.
Topics: Adult; Amino Acid Sequence; Aspartic Acid; Female; Fetal Blood; Fetal Hemoglobin; Genetic Carrier Screening; Hemoglobin A; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Macromolecular Substances; Male; Molecular Sequence Data; Oxyhemoglobins; Point Mutation | 1994 |
C4 gene polymorphism in primates: evolution, generation, and Chido and Rodgers antigenicity.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Biological Evolution; Cell Line; Complement C4; DNA; Epitopes; Histidine; Molecular Sequence Data; Polymorphism, Genetic; Primates; Species Specificity | 1994 |
Effect of adjacent histidine and cysteine residues on the spontaneous degradation of asparaginyl- and aspartyl-containing peptides.
Topics: Adrenocorticotropic Hormone; Amides; Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Cysteine; Histidine; Molecular Sequence Data; Oligopeptides; Stereoisomerism | 1995 |
Polar pathway for percutaneous absorption.
Topics: Aspartic Acid; Biological Transport; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Histidine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lysine; Models, Biological; Skin Absorption | 1995 |
Crystal structure of a complement factor D mutant expressing enhanced catalytic activity.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Binding Sites; Catalysis; Cattle; Chymotrypsinogen; Histidine; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Swine | 1995 |
Replacements of histidine 226 of NhaA-Na+/H+ antiporter of Escherichia coli. Cysteine (H226C) or serine (H226S) retain both normal activity and pH sensitivity, aspartate (H226D) shifts the pH profile toward basic pH, and alanine (H226A) inactivates the ca
Topics: Alanine; Aspartic Acid; Codon; Cysteine; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Phenotype; Point Mutation; Serine; Sodium-Hydrogen Exchangers | 1995 |
The catalytic triad of the influenza C virus glycoprotein HEF esterase: characterization by site-directed mutagenesis and functional analysis.
Topics: Acetylesterase; Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Carboxylic Ester Hydrolases; Cell Line; Dogs; Enzyme Inhibitors; Gammainfluenzavirus; Hemagglutinin Glycoproteins, Influenza Virus; Hemagglutinins, Viral; Histidine; Isoflurophate; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Recombinant Fusion Proteins; Serine; Serine Endopeptidases; Sialic Acids; Viral Fusion Proteins; Viral Proteins | 1995 |
Blood urea and amino acid concentrations in pigs of two breed combinations as affected by energy intakes.
Topics: Amino Acids; Animals; Aspartic Acid; Blood Urea Nitrogen; Chromatography, High Pressure Liquid; Crosses, Genetic; Diet; Energy Intake; Energy Metabolism; Glutamic Acid; Histidine; Lysine; Male; Swine; Tyrosine; Weight Gain | 1995 |
A low-barrier hydrogen bond in the catalytic triad of serine proteases.
Topics: Aspartic Acid; Catalysis; Chymotrypsin; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Maleates; Malonates; Serine; Serine Endopeptidases; Temperature; Urocanic Acid | 1994 |
Functions of electrostatic potentials and conserved distal and proximal His-Asp H-bonding networks in haem peroxidases.
Topics: Amino Acid Sequence; Aspartic Acid; Conserved Sequence; Cytochrome-c Peroxidase; Electrochemistry; Hemeproteins; Histidine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Peroxidases; Plants; Protein Conformation | 1995 |
Structure and function of the catalytic site mutant Asp 99 Asn of phospholipase A2: absence of the conserved structural water.
Topics: Animals; Asparagine; Aspartic Acid; Binding Sites; Cattle; Computer Graphics; Crystallography, X-Ray; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Pancreas; Phospholipases A; Phospholipases A2; Point Mutation; Water | 1994 |
Molecular and biochemical evidence for the involvement of the Asp-333-His-523 pair in the catalytic mechanism of soluble epoxide hydrolase.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Catalysis; Cloning, Molecular; Epoxide Hydrolases; Histidine; Mice; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Peptide Mapping; Solubility; Spodoptera; Trypsin | 1995 |
Low-barrier hydrogen bonds.
Topics: Aspartic Acid; Chymotrypsin; Histidine; Hydrogen Bonding | 1995 |
Amino acid residues that influence the binding of manganese or calcium to photosystem II. 1. The lumenal interhelical domains of the D1 polypeptide.
Topics: Amino Acids; Aspartic Acid; Calcium; Cyanobacteria; Electron Transport; Glutamic Acid; Histidine; Light; Light-Harvesting Protein Complexes; Manganese; Mutagenesis, Site-Directed; Photochemistry; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Plastoquinone; Protein Structure, Secondary; Spectrometry, Fluorescence; Structure-Activity Relationship; Tyrosine | 1995 |
Amino acid residues that influence the binding of manganese or calcium to photosystem II. 2. The carboxy-terminal domain of the D1 polypeptide.
Topics: Amino Acids; Aspartic Acid; Calcium; Chlorophyll; Chlorophyll A; Cyanobacteria; Electron Transport; Glutamic Acid; Histidine; Kinetics; Light; Light-Harvesting Protein Complexes; Manganese; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Peptide Fragments; Photochemistry; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Plastoquinone; Structure-Activity Relationship; Water | 1995 |
Comparison of the structure of wild-type HtrA heat shock protease and mutant HtrA proteins. A Fourier transform infrared spectroscopic study.
Topics: Aspartic Acid; Bacterial Proteins; Binding Sites; Escherichia coli; Genes, Bacterial; Heat-Shock Proteins; Histidine; Hot Temperature; Kinetics; Mutagenesis, Site-Directed; Periplasmic Proteins; Point Mutation; Protein Denaturation; Protein Structure, Secondary; Recombinant Proteins; Serine; Serine Endopeptidases; Spectroscopy, Fourier Transform Infrared; Thermodynamics | 1995 |
Site-directed mutagenesis of Thermus thermophilus elongation factor Tu. Replacement of His85, Asp81 and Arg300.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Base Sequence; DNA Primers; Escherichia coli; Gene Expression; GTP Phosphohydrolase-Linked Elongation Factors; Histidine; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Elongation Factor Tu; Protein Structure, Tertiary; RNA, Transfer, Amino Acyl; Structure-Activity Relationship; Thermus thermophilus | 1995 |
Low-barrier hydrogen bonding in molecular complexes analogous to histidine and aspartate in the catalytic triad of serine proteases.
Topics: Aspartic Acid; Carboxylic Acids; Catalysis; Histidine; Hydrogen Bonding; Imidazoles; Magnetic Resonance Spectroscopy; Serine Endopeptidases; Spectroscopy, Fourier Transform Infrared | 1995 |
Computer modelling of the alpha-helical coiled coil: packing of side-chains in the inner core.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Computer Simulation; Cysteine; Glutamates; Glutamine; Histidine; Hydrogen Bonding; Isoleucine; Leucine; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Serine; Thermodynamics; Threonine; Tyrosine; Valine | 1995 |
The Asp116-His116 substitution in a novel HLA-B27 subtype influences the acceptance of the peptide C-terminal anchor.
Topics: Antibodies, Monoclonal; Aspartic Acid; Binding Sites; Binding, Competitive; Cells, Cultured; Histidine; HLA-B27 Antigen; Peptides | 1995 |
[Hasharon hemoglobinopathy in a family].
Topics: Adolescent; Aspartic Acid; Globins; Hemoglobinopathies; Histidine; Humans; Male; Pedigree | 1994 |
Reconsideration of the essential role of a histidine residue of L-2-halo acid dehalogenase.
Topics: Aspartic Acid; Bacterial Proteins; Binding Sites; Catalysis; Histidine; Hydrolases; Kinetics; Mutagenesis, Site-Directed; Pseudomonas; Substrate Specificity | 1994 |
Cold lability of the mutant forms of Escherichia coli inorganic pyrophosphatase.
Topics: Aspartic Acid; Binding Sites; Cold Temperature; Escherichia coli; Glutamic Acid; Glutamine; Histidine; Kinetics; Macromolecular Substances; Magnesium; Mutagenesis, Site-Directed; Pyrophosphatases; Structure-Activity Relationship | 1995 |
The proteasome from Thermoplasma acidophilum is neither a cysteine nor a serine protease.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Cell Line, Transformed; Cysteine; Cysteine Endopeptidases; Histidine; Humans; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis; Proteasome Endopeptidase Complex; Sequence Homology, Amino Acid; Serine Endopeptidases; Thermoplasma | 1995 |
Site-directed mutagenesis of histidine 93, aspartic acid 180, glutamic acid 205, histidine 290, and aspartic acid 291 at the active site and tryptophan 279 at the raw starch binding site in barley alpha-amylase 1.
Topics: alpha-Amylases; Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; Cloning, Molecular; DNA Primers; Glutamates; Glutamic Acid; Histidine; Hordeum; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Recombinant Proteins; Saccharomyces cerevisiae; Tryptophan | 1993 |
Copper(II) complexes of dipeptides containing aspartyl, glutamyl, and histidyl residues in the side chain.
Topics: Aspartic Acid; Copper; Dipeptides; Glutamates; Glutamic Acid; Histidine; Metals; Protein Binding | 1993 |
Improved continuum electrostatic modelling in proteins, with comparison to experiment.
Topics: Amino Acid Sequence; Aspartic Acid; Bacillus; Binding Sites; Calcium; Electrochemistry; Glutamates; Glutamic Acid; Histidine; Mathematics; Models, Molecular; Mutagenesis, Site-Directed; Osmolar Concentration; Protein Conformation; Protein Folding; Recombinant Proteins; Solvents; Subtilisins | 1994 |
Catalysis by Syrian hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Proposed roles of histidine 865, glutamate 558, and aspartate 766.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Catalysis; Cloning, Molecular; Cricetinae; Glutamates; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Hydroxymethylglutaryl CoA Reductases; Kinetics; Mesocricetus; Models, Theoretical; Mutagenesis, Site-Directed; Peptide Fragments; Point Mutation; Recombinant Proteins | 1994 |
Characterization of antimycin resistant mutants of Rhodospirillum rubrum.
Topics: Amino Acid Sequence; Antimycin A; Aspartic Acid; Cytochrome b Group; Drug Resistance, Microbial; Electron Transport Complex III; Genes, Fungal; Glutamates; Glutamic Acid; Histidine; Point Mutation; Rhodospirillum rubrum | 1994 |
Influence of six mutations of the protein C gene on the Gla domain conformation and calcium affinity.
Topics: 1-Carboxyglutamic Acid; Adult; Amino Acid Sequence; Antibodies, Monoclonal; Arginine; Aspartic Acid; Calcium; Chromatography, Ion Exchange; Cysteine; Enzyme-Linked Immunosorbent Assay; Histidine; Humans; Male; Molecular Sequence Data; Mutation; Protein C; Protein Structure, Tertiary | 1994 |
Substrate recognition by casein kinase-II: the role of histidine-160.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Baculoviridae; Base Sequence; Binding Sites; Casein Kinase II; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Proteins; Serine; Spodoptera; Structure-Activity Relationship; Substrate Specificity; Threonine | 1994 |
The effect of replacing the conserved active-site residues His-264, Asp-312 and Arg-314 on the binding and catalytic properties of Escherichia coli citrate synthase.
Topics: Anilino Naphthalenesulfonates; Arginine; Aspartic Acid; Base Sequence; Binding Sites; Catalysis; Citrate (si)-Synthase; Dithionitrobenzoic Acid; Escherichia coli; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Protein Conformation; Structure-Activity Relationship | 1994 |
Active site coordination chemistry of the cytochrome c peroxidase Asp235Ala variant: spectroscopic and functional characterization.
Topics: Alanine; Aspartic Acid; Base Sequence; Binding Sites; Cytochrome-c Peroxidase; Electron Spin Resonance Spectroscopy; Heme; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Iron; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Recombinant Proteins; Spectrum Analysis; Structure-Activity Relationship; Temperature; Tryptophan | 1994 |
Catalytically important domains of rat carnitine palmitoyltransferase II as determined by site-directed mutagenesis and chemical modification. Evidence for a critical histidine residue.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Carnitine O-Palmitoyltransferase; Catalysis; Citrate (si)-Synthase; Diethyl Pyrocarbonate; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship | 1994 |
Selection of a gyrA mutant of Mycobacterium tuberculosis resistant to fluoroquinolones during treatment with ofloxacin.
Topics: Adult; Antitubercular Agents; Aspartic Acid; Base Sequence; DNA Gyrase; DNA Primers; DNA Topoisomerases, Type II; DNA, Bacterial; Drug Resistance, Microbial; Female; Histidine; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mycobacterium tuberculosis; Ofloxacin; Point Mutation; Polymerase Chain Reaction; Tuberculosis, Pulmonary | 1994 |
The effect of the Asn82-->Asp mutation in yeast cytochrome c peroxidase studied by proton NMR spectroscopy.
Topics: Asparagine; Aspartic Acid; Cytochrome-c Peroxidase; Histidine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Mutation; Saccharomyces cerevisiae | 1994 |
Holoenzyme interaction sites in the cAMP-dependent protein kinase. Histidine 87 in the catalytic subunit complements serine 99 in the type I regulatory subunit.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Chromatography, Gel; Cloning, Molecular; Cyclic AMP-Dependent Protein Kinases; Escherichia coli; Histidine; Kinetics; Macromolecular Substances; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Serine | 1994 |
Four newly identified ornithine transcarbamylase (OTC) mutations (D126G, R129H, I172M and W332X) in Japanese male patients with early-onset OTC deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Arginine; Aspartic Acid; Base Sequence; DNA Mutational Analysis; DNA Primers; DNA, Single-Stranded; Glycine; Histidine; Humans; Infant; Infant, Newborn; Isoleucine; Male; Methionine; Molecular Epidemiology; Molecular Sequence Data; Nucleic Acid Conformation; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Tryptophan; X Chromosome | 1994 |
Local pH-dependent conformational changes leading to proteolytic susceptibility of cystatin C.
Topics: Amino Acid Sequence; Aspartic Acid; Circular Dichroism; Crystallography, X-Ray; Cystatin C; Cystatins; Cysteine Proteinase Inhibitors; Glycine; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Osmolar Concentration; Protein Conformation | 1994 |
Production of bioactive rabbit antibodies against the mutated receptor peptide TSH-R-HIS17 and detection of hypertriiodothyroninemia in the rabbit.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Autoantibodies; Histidine; Immunoglobulins, Thyroid-Stimulating; Molecular Sequence Data; Mutation; Peptide Fragments; Rabbits; Receptors, Thyrotropin; Triiodothyronine | 1993 |
Identification of serine 624, aspartic acid 702, and histidine 734 as the catalytic triad residues of mouse dipeptidyl-peptidase IV (CD26). A member of a novel family of nonclassical serine hydrolases.
Topics: Amino Acid Sequence; Animals; Antigens, Differentiation, T-Lymphocyte; Aspartic Acid; Catalysis; Cells, Cultured; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Histidine; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Precipitin Tests; Protein Structure, Secondary; Restriction Mapping; Serine; Transfection | 1993 |
Investigating the role of conserved residue Asp134 in Escherichia coli ribonuclease HI by site-directed random mutagenesis.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Base Sequence; Circular Dichroism; Conserved Sequence; DNA Primers; Enzyme Stability; Escherichia coli; Genes, Bacterial; Histidine; Hot Temperature; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Polymerase Chain Reaction; Protein Denaturation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Ribonuclease H; Suppression, Genetic; Thermodynamics | 1994 |
Potential active-site base of thioredoxin reductase from Escherichia coli: examination of histidine245 and aspartate139 by site-directed mutagenesis.
Topics: Aspartic Acid; Base Sequence; Binding Sites; Crystallography, X-Ray; Escherichia coli; Histidine; Kinetics; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; NADP; Oxidation-Reduction; Spectrometry, Fluorescence; Structure-Activity Relationship; Thioredoxin-Disulfide Reductase | 1994 |
Structural investigation of catalytically modified F120L and F120Y semisynthetic ribonucleases.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Crystallography, X-Ray; Glutamine; Histidine; Hydrogen Bonding; Lysine; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Protein Conformation; Ribonucleases; Software; Water | 1994 |
Arginine metabolism in the salivary glands of protein-deficient rats and its potential association with the oral microflora.
Topics: Amino Acids, Essential; Animals; Arginase; Arginine; Aspartic Acid; Bacteria; Histidine; Lysine; Male; Mouth; Ornithine; Protein Deficiency; Rats; Rats, Sprague-Dawley; Saliva; Submandibular Gland; Tyrosine | 1994 |
Converting tissue plasminogen activator to a zymogen: a regulatory triad of Asp-His-Ser.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Catalysis; Chymotrypsin; Enzyme Precursors; Histidine; Hydrogen Bonding; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasminogen; Plasminogen Activator Inhibitor 1; Serine; Tissue Plasminogen Activator | 1993 |
Probing the active site of human aldose reductase. Site-directed mutagenesis of Asp-43, Tyr-48, Lys-77, and His-110.
Topics: Aldehyde Reductase; Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; DNA Primers; Female; Histidine; Humans; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Placenta; Pregnancy; Protein Conformation; Recombinant Proteins; Tyrosine | 1993 |
Specific amino acids modulate the embryotoxicity of nickel chloride and its transfer to the rat embryo in vitro.
Topics: Amino Acids; Animals; Aspartic Acid; Biological Transport; Cysteine; Embryo, Mammalian; Embryonic and Fetal Development; Female; Histidine; Nickel; Organ Culture Techniques; Pregnancy; Protein Binding; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1993 |
Probing actin incorporation into myofibrils using Asp11 and His73 actin mutants.
Topics: Actins; Adenosine Triphosphate; Animals; Aspartic Acid; Chickens; Female; Histidine; Molecular Probes; Mutation; Myofibrils; Reference Values | 1993 |
Type IIB mutation His-505-->Asp implicates a new segment in the control of von Willebrand factor binding to platelet glycoprotein Ib.
Topics: Alleles; Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; Blood Platelets; Crotalid Venoms; DNA; Electrophoresis, Agar Gel; Female; Hemagglutinins; Histidine; Humans; Kinetics; Middle Aged; Molecular Sequence Data; Oligodeoxyribonucleotides; Plasmids; Platelet Membrane Glycoproteins; Point Mutation; Polymerase Chain Reaction; Recombinant Proteins; Ristocetin; von Willebrand Diseases; von Willebrand Factor | 1993 |
The Asp-His-Fe triad of cytochrome c peroxidase controls the reduction potential, electronic structure, and coupling of the tryptophan free radical to the heme.
Topics: Aspartic Acid; Binding Sites; Crystallography; Cytochrome-c Peroxidase; DNA Mutational Analysis; Electron Spin Resonance Spectroscopy; Ferric Compounds; Free Radicals; Heme; Histidine; Hydrogen Bonding; In Vitro Techniques; Kinetics; Models, Molecular; Oxidation-Reduction; Recombinant Proteins; Structure-Activity Relationship; Tryptophan; X-Ray Diffraction | 1993 |
Effects of intra- and intersubunit hydrogen bonds on the R-T transition in human hemoglobin as studied with alpha 42(C7) and beta 145(HC2) mutations.
Topics: Amino Acid Sequence; Aspartic Acid; Carbon Monoxide; Escherichia coli; Hemoglobin A; Histidine; Humans; Hydrogen Bonding; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Thermodynamics; Tyrosine | 1993 |
Determination of tumor aggressiveness in colorectal cancer by K-ras-2 analysis.
Topics: Adenocarcinoma; Aspartic Acid; Biomarkers, Tumor; Codon; Colonic Neoplasms; DNA, Neoplasm; Exons; Follow-Up Studies; Genes, ras; Glutamine; Histidine; Humans; Mutation; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Rectal Neoplasms; Retrospective Studies; Survival Rate; Valine | 1993 |
Role of the conserved histidine and aspartic acid residues in activity and stabilization of human gelatinase B: an example of matrix metalloproteinases.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Calcium; Catalysis; Collagenases; Conserved Sequence; Enzyme Stability; Histidine; Humans; Matrix Metalloproteinase 9; Molecular Sequence Data; Structure-Activity Relationship; Zinc | 1995 |
Identification of the catalytic triad of the lipase/acyltransferase from Aeromonas hydrophila.
Topics: Acyltransferases; Aeromonas hydrophila; Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; Catalysis; DNA, Bacterial; Histidine; Lipase; Molecular Sequence Data; Mutagenesis, Site-Directed; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship | 1996 |
Site-directed mutagenesis of human lysyl hydroxylase expressed in insect cells. Identification of histidine residues and an aspartic acid residue critical for catalytic activity.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Baculoviridae; Base Sequence; Binding Sites; Cell Line; Codon; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; Histidine; Humans; Kinetics; Molecular Weight; Mutagenesis, Site-Directed; Point Mutation; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; Recombinant Proteins; Spodoptera; Transfection | 1996 |
Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Catalysis; Cloning, Molecular; DNA Primers; Epoxide Hydrolases; Escherichia coli; Histidine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Protein Structure, Secondary; Rats; Recombinant Proteins; Restriction Mapping; Sequence Homology, Amino Acid | 1996 |
Asp76 is the Schiff base counterion and proton acceptor in the proton-translocating form of sensory rhodopsin I.
Topics: Aspartic Acid; Bacteriorhodopsins; Darkness; Halorhodopsins; Histidine; Hydrogen-Ion Concentration; Kinetics; Lasers; Recombinant Proteins; Schiff Bases; Sensory Receptor Cells; Sensory Rhodopsins; Sequence Tagged Sites; Spectrophotometry; Spectroscopy, Fourier Transform Infrared | 1996 |
A yeast phosphofructokinase insensitive to the allosteric activator fructose 2,6-bisphosphate. Glycolysis/metabolic regulation/allosteric control.
Topics: Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Aspartic Acid; Base Sequence; DNA Primers; Enzyme Activation; Fructosediphosphates; Glycolysis; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphofructokinase-1; Point Mutation; Polymerase Chain Reaction; Promoter Regions, Genetic; Recombinant Proteins; Saccharomyces cerevisiae; Serine | 1996 |
EXAFS investigation of the active site of iron superoxide dismutase of Escherichia coli and Propionibacterium shermanii.
Topics: Amino Acid Sequence; Aspartic Acid; Crystallography, X-Ray; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Iron; Molecular Sequence Data; Propionibacterium; Protein Structure, Secondary; Spectrophotometry, Atomic; Superoxide Dismutase | 1996 |
The catalytic site of chloroplastic NADP-dependent malate dehydrogenase contains a His/Asp pair.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Binding Sites; Chloroplasts; Histidine; Hydrogen-Ion Concentration; Kinetics; Malate Dehydrogenase; Malate Dehydrogenase (NADP+); Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Plants; Point Mutation; Recombinant Proteins; Sequence Homology, Amino Acid | 1996 |
Functional properties of the histidine-aspartate ion pair of flavocytochrome b2 (L-lactate dehydrogenase): substitution of Asp282 with asparagine.
Topics: Asparagine; Aspartic Acid; Escherichia coli; Histidine; Ions; Isotopes; Kinetics; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Lactates; Lactic Acid; Mutagenesis, Site-Directed; Recombinant Proteins | 1996 |
Identification of essential residues for the catalytic function of 85-kDa cytosolic phospholipase A2. Probing the role of histidine, aspartic acid, cysteine, and arginine.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Aspartic Acid; Biological Evolution; Catalysis; Conserved Sequence; Cysteine; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phospholipases A; Phospholipases A2; Sequence Homology, Amino Acid | 1996 |
Mitochondrial phosphate transport protein. replacements of glutamic, aspartic, and histidine residues affect transport and protein conformation and point to a coupled proton transport path.
Topics: Amino Acid Sequence; Aspartic Acid; Carrier Proteins; Glutamic Acid; Histidine; Ion Transport; Molecular Sequence Data; Mutagenesis; Phosphate-Binding Proteins; Phosphates; Protein Conformation; Protons; Sequence Homology, Amino Acid | 1996 |
Two mutations of the lutropin/choriogonadotropin receptor that impair signal transduction also interfere with receptor-mediated endocytosis.
Topics: Arginine; Asparagine; Aspartic Acid; Cell Line; Chorionic Gonadotropin; Cyclic AMP; Embryo, Mammalian; Endocytosis; Histidine; Humans; Kidney; Mutagenesis; Protein Conformation; Receptors, LH; Signal Transduction; Transfection | 1996 |
Woodward's reagent K inactivation of Escherichia coli L-threonine dehydrogenase: increased absorbance at 340-350 nm is due to modification of cysteine and histidine residues, not aspartate or glutamate carboxyl groups.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Cysteine; Enzyme Inhibitors; Escherichia coli; Glutamic Acid; Histidine; Isoxazoles; Kinetics; Models, Chemical; Molecular Sequence Data; Solvents; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 1996 |
Derivation of 3D coordinate templates for searching structural databases: application to Ser-His-Asp catalytic triads in the serine proteinases and lipases.
Topics: Amino Acid Isomerases; Aspartic Acid; Bacterial Proteins; Binding Sites; Carrier Proteins; Databases, Factual; Histidine; Immunoglobulin G; Lipase; Peptide Fragments; Peptidylprolyl Isomerase; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Proteins; Sequence Analysis; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Templates, Genetic | 1996 |
Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 "two-component" osmosensor.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cloning, Molecular; DNA-Binding Proteins; Fungal Proteins; Genes, Fungal; Histidine; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phenotype; Phosphorylation; Protein Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Water-Electrolyte Balance | 1996 |
Identification of potential active-site residues in the hydroxynitrile lyase from Manihot esculenta by site-directed mutagenesis.
Topics: Aldehyde-Lyases; Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; Electrophoresis, Polyacrylamide Gel; Histidine; Manihot; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitriles; Sequence Alignment; Serine | 1996 |
A single nucleotide change in the E protein gene of dengue virus 2 Mexican strain affects neurovirulence in mice.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Cell Line; Dengue Virus; DNA, Viral; Genetic Variation; Histidine; Macaca mulatta; Mexico; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Point Mutation; RNA, Viral; Sequence Homology, Amino Acid; Viral Envelope Proteins; Virulence | 1996 |
Active site structure in cytochrome c peroxidase and myoglobin mutants: effects of altered hydrogen bonding to the proximal histidine.
Topics: Aspartic Acid; Binding Sites; Cytochrome-c Peroxidase; Histidine; Hydrogen Bonding; Leucine; Mutagenesis; Myoglobin; Protein Conformation; Spectrum Analysis; X-Rays | 1996 |
Nucleoside-diphosphate kinase-mediated signal transduction via histidyl-aspartyl phosphorelay systems in Escherichia coli.
Topics: Aspartic Acid; Bacterial Outer Membrane Proteins; Bacterial Proteins; Escherichia coli; Escherichia coli Proteins; Guanosine Triphosphate; Histidine; Histidine Kinase; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Multienzyme Complexes; Nucleoside-Diphosphate Kinase; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinases; Signal Transduction | 1996 |
T4 endonuclease VII. Importance of a histidine-aspartate cluster within the zinc-binding domain.
Topics: Amino Acid Sequence; Aspartic Acid; Bacteriophage T4; Binding Sites; DNA; DNA-Binding Proteins; Endodeoxyribonucleases; Histidine; Metalloproteins; Molecular Sequence Data; Protein Conformation; Zinc | 1996 |
1H-NMR study of inter-segmental hydrogen bonds in sperm whale and horse apomyoglobins.
Topics: Animals; Apoproteins; Aspartic Acid; Guanidine; Guanidines; Heme; Histidine; Horses; Hydrogen Bonding; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Myoglobin; Protein Conformation; Protein Denaturation; Temperature; Whales | 1997 |
Ion-pair and charged hydrogen-bond interactions between histidine and aspartate in a peptide helix.
Topics: Amino Acid Sequence; Aspartic Acid; Histidine; Hydrogen; Hydrogen Bonding; Molecular Sequence Data; Peptides; Protein Folding | 1997 |
Identification of essential aspartic acid and histidine residues of hormone-sensitive lipase: apparent residues of the catalytic triad.
Topics: Animals; Aspartic Acid; Binding Sites; Catalysis; COS Cells; Histidine; Models, Molecular; Mutagenesis, Site-Directed; Rats; Sterol Esterase | 1997 |
Primary structure and functional analysis of the soluble transducer protein HtrXI in the archaeon Halobacterium salinarium.
Topics: Amino Acid Sequence; Archaeal Proteins; Aspartic Acid; Chemotaxis; Cloning, Molecular; Genes, Bacterial; Glutamic Acid; Halobacterium; Histidine; Methyltransferases; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Deletion; Signal Transduction; Solubility; Zinc Fingers | 1997 |
Identification of N-acetylaspartate in the lens of the vertebrate eye: a new model for the investigation of the function of N-acetylated amino acids in vertebrates.
Topics: Animals; Aspartic Acid; Brain Chemistry; Fishes; Histidine; Lens, Crystalline; Rats; Retina; Swine | 1997 |
Engineering subunit association of multisubunit proteins: a dimeric streptavidin.
Topics: Aspartic Acid; Bacterial Proteins; Binding Sites; Biotin; Cloning, Molecular; Dimerization; DNA Primers; Entropy; Escherichia coli; Histidine; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Protein Conformation; Protein Engineering; Protein Structure, Secondary; Recombinant Proteins; Static Electricity; Streptavidin; Thermodynamics | 1997 |
Human lysosomal acid lipase/cholesteryl ester hydrolase and human gastric lipase: identification of the catalytically active serine, aspartic acid, and histidine residues.
Topics: Animals; Aspartic Acid; Binding Sites; DNA, Complementary; Histidine; Humans; Hydrolysis; Lipase; Mutagenesis, Site-Directed; Rats; Serine; Substrate Specificity | 1997 |
Evidence supporting a role for histidine-235 in cation binding to human 3-hydroxy-3-methyglutaryl-CoA lyase.
Topics: Alanine; Aspartic Acid; Binding Sites; Catalysis; Cations, Divalent; Diethyl Pyrocarbonate; Electron Spin Resonance Spectroscopy; Histidine; Humans; Kinetics; Magnesium; Manganese; Mutagenesis, Site-Directed; Oxo-Acid-Lyases; Polymerase Chain Reaction; Structure-Activity Relationship | 1997 |
How enzymes control the reactivity of adenosylcobalamin: effect on coenzyme binding and catalysis of mutations in the conserved histidine-aspartate pair of glutamate mutase.
Topics: Amino Acid Isomerases; Aspartic Acid; Catalysis; Cobamides; Coenzymes; Histidine; Intramolecular Transferases; Mutagenesis, Site-Directed; Protein Binding; Recombinant Proteins; Spectrophotometry, Ultraviolet | 1997 |
A Ni2+ binding motif is the basis of high affinity transport of the Alcaligenes eutrophus nickel permease.
Topics: Alcaligenes; Alkaline Phosphatase; Amino Acid Sequence; Antiporters; Aspartic Acid; ATP-Binding Cassette Transporters; Bacterial Proteins; Binding Sites; Biological Transport; Carrier Proteins; Cysteine; Escherichia coli; Escherichia coli Proteins; Histidine; Hydrogenase; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Nickel | 1997 |
Genetic and clinical description of hemochromatosis probands and heterozygotes: evidence that multiple genes linked to the major histocompatibility complex are responsible for hemochromatosis.
Topics: Adult; Alleles; Aspartic Acid; Chromosomes, Human, Pair 6; Cysteine; Female; Gene Frequency; Genes, MHC Class I; Genetic Linkage; Hemochromatosis; Heterozygote; Histidine; Histocompatibility Testing; HLA Antigens; Homozygote; Humans; Iron; Male; Middle Aged; Mutation; Tyrosine; White People | 1997 |
Ribonuclease T1 is active when both catalytic histidines are replaced by aspartate.
Topics: Aspartic Acid; Binding Sites; Catalysis; Enzyme Activation; Histidine; Mutagenesis, Site-Directed; Ribonuclease T1; Structure-Activity Relationship | 1997 |
Regiospecificity and catalytic triad of lysophospholipase I.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Catalysis; Circular Dichroism; Histidine; Lysophospholipase; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Rats; Serine; Substrate Specificity | 1997 |
Functional effects on the acetylcholine receptor of multiple mutations of gamma Asp174 and delta Asp180.
Topics: Affinity Labels; Animals; Asparagine; Aspartic Acid; Binding, Competitive; Bungarotoxins; Histidine; Hydrogen-Ion Concentration; Membrane Potentials; Mice; Mutagenesis, Site-Directed; Quaternary Ammonium Compounds; Receptors, Cholinergic; Tubocurarine | 1997 |
Site-directed mutagenesis of maize recombinant C4-pyruvate,orthophosphate dikinase at the phosphorylatable target threonine residue.
Topics: Adenosine Diphosphate; Aspartic Acid; Histidine; Mutagenesis, Site-Directed; Phosphorylation; Pyruvate, Orthophosphate Dikinase; Serine; Threonine; Valine; Zea mays | 1997 |
In vivo mutational analysis of highly conserved amino acid residues of the small subunit Cpa1p of the carbamylphosphate synthetase of Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Ammonia; Ammonium Sulfate; Arginine; Aspartic Acid; Carbon-Nitrogen Ligases; Chromosome Mapping; Cysteine; Gene Expression; Glutaminase; Glutamine; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Proline; Saccharomyces cerevisiae; Sequence Analysis; Sequence Deletion; Transformation, Genetic | 1997 |
Aspartate 171 is the major primate-specific determinant of human growth hormone. Engineering porcine growth hormone to activate the human receptor.
Topics: Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Binding Sites; Cell Division; Cell Line; Growth Hormone; Histidine; Human Growth Hormone; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Primates; Rabbits; Receptors, Somatotropin; Swine; Transfection | 1997 |
A low-barrier hydrogen bond in the catalytic triad of serine proteases? Theory versus experiment.
Topics: Aspartic Acid; Binding Sites; Boronic Acids; Catalysis; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Oligopeptides; Protons; Serine Endopeptidases; Serine Proteinase Inhibitors; Subtilisins; Temperature; Urocanic Acid | 1997 |
The tortuous story of Asp ... His ... Ser: structural analysis of alpha-chymotrypsin.
Topics: Amino Acid Sequence; Aspartic Acid; Chymotrypsin; Histidine; Protein Structure, Tertiary; Serine | 1997 |
Severely impaired polymerization of recombinant fibrinogen gamma-364 Asp --> His, the substitution discovered in a heterozygous individual.
Topics: Amino Acid Substitution; Animals; Aspartic Acid; CHO Cells; Cricetinae; Fibrinogen; Heterozygote; Histidine; Models, Molecular; Polymers; Recombinant Proteins; Thrombin | 1997 |
Structure and function of poly(3-hydroxybutyrate) depolymerase from Alcaligenes faecalis T1.
Topics: Alcaligenes; Asparagine; Aspartic Acid; Carboxylic Ester Hydrolases; Chromosome Inversion; DNA Primers; DNA, Bacterial; Gene Expression; Glycine; Histidine; Plasmids; Point Mutation; Polymerase Chain Reaction; Recombinant Fusion Proteins; Sequence Deletion; Serine; Trypsin | 1997 |
Characterization of Leuconostoc mesenteroides NRRL B-512F dextransucrase (DSRS) and identification of amino-acid residues playing a key role in enzyme activity.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Catalysis; Dextrans; Escherichia coli; Genes, Bacterial; Glucosyltransferases; Histidine; Hydrogen Bonding; Leuconostoc; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Sucrose | 1997 |
The molecular chaperone function of the secretory vesicle cysteine string proteins.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Animals; Aspartic Acid; Carrier Proteins; Cattle; Cell Line; Exocytosis; Histidine; HSC70 Heat-Shock Proteins; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Luciferases; Membrane Proteins; Nerve Tissue Proteins; Protein Binding; Protein Denaturation; Trypsin | 1997 |
Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
Topics: Alkynes; Ammonium Sulfate; Apoproteins; Aspartic Acid; Biotin; Crystallography, X-Ray; Dimerization; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Imidazoles; Ligands; Models, Molecular; Osmolar Concentration; Protein Conformation; Sodium Chloride; Solubility; Streptavidin | 1997 |
Succinoglycan production by Rhizobium meliloti is regulated through the ExoS-ChvI two-component regulatory system.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cell Membrane; Cloning, Molecular; Cytoplasm; Genes, Bacterial; Genes, Regulator; Histidine; Histidine Kinase; Molecular Sequence Data; Molecular Weight; Phosphorylation; Polysaccharides, Bacterial; Protein Kinases; Recombinant Fusion Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sinorhizobium meliloti; Transcription Factors | 1998 |
On the mechanism of the reaction catalyzed by glucose 6-phosphate dehydrogenase.
Topics: Aspartic Acid; Catalysis; Glucosephosphate Dehydrogenase; Histidine; Leuconostoc; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation | 1998 |
An Escherichia coli protein that exhibits phosphohistidine phosphatase activity towards the HPt domain of the ArcB sensor involved in the multistep His-Asp phosphorelay.
Topics: Amino Acid Sequence; Artificial Gene Fusion; Aspartic Acid; Autoradiography; Bacterial Outer Membrane Proteins; Bacterial Proteins; Base Sequence; beta-Galactosidase; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Genes, Bacterial; Histidine; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphates; Phosphoenolpyruvate Sugar Phosphotransferase System; Plasmids; Protein Kinases; Signal Transduction; Structure-Activity Relationship; Transformation, Genetic | 1998 |
Hb Sassari [alpha 126(H9)Asp-->His] results from a GAC-->CAC mutation in the alpha 1-globin gene.
Topics: Amino Acid Substitution; Aspartic Acid; Female; Globins; Hemoglobins, Abnormal; Histidine; Humans; Male; Mutation | 1998 |
A conserved histidine is essential for glycerolipid acyltransferase catalysis.
Topics: Acyltransferases; Alanine; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Cell Membrane; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Gene Expression; Genetic Complementation Test; Glutamic Acid; Glycerol-3-Phosphate O-Acyltransferase; Histidine; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Protein Biosynthesis; Sequence Alignment; Sequence Analysis, DNA; Transcription, Genetic | 1998 |
Lysine and arginine residues in the N-terminal 18% of apolipoprotein B are critical for its binding to microsomal triglyceride transfer protein.
Topics: Apolipoproteins B; Arginine; Aspartic Acid; Binding Sites; Carrier Proteins; Cell Line; Glutamic Acid; Heparin; Histidine; Humans; Lysine; Microsomes; Protein Binding; Receptors, LDL | 1998 |
Mechanism of phosphatidylinositol-specific phospholipase C: a unified view of the mechanism of catalysis.
Topics: Alcohols; Aspartic Acid; Binding Sites; Catalysis; Circular Dichroism; Escherichia coli; Esterification; Guanidine; Histidine; Inositol Phosphates; Kinetics; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoinositide Phospholipase C; Protein Conformation; Protein Denaturation; Recombinant Proteins; Type C Phospholipases | 1998 |
A ligand-mimetic model for constitutive activation of the melanocortin-1 receptor.
Topics: Alleles; Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Conserved Sequence; Foxes; Genes, Dominant; Glutamic Acid; Hair Color; Histidine; Ligands; Lysine; Mice; Models, Genetic; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Receptors, Corticotropin; Receptors, Melanocortin; Sheep | 1998 |
HFE codon 63/282 (H63D/C282Y) dimorphism in German patients with genetic hemochromatosis.
Topics: Aspartic Acid; Codon; Cysteine; Female; Genotype; Germany; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Male; Membrane Proteins; Point Mutation; Polymorphism, Genetic; Tyrosine | 1998 |
His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Cattle; Crystallography, X-Ray; Histidine; Hydrogen-Ion Concentration; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Ribonuclease, Pancreatic; Structure-Activity Relationship | 1998 |
Identification of the catalytic triad of the protein D2 protease in Pseudomonas aeruginosa.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Carbapenems; Catalysis; Endopeptidases; Glutamine; Histidine; Imipenem; Ion Channels; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Porins; Pseudomonas aeruginosa; Serine | 1998 |
Electrophilic assistance by Asp-99 of 3-oxo-Delta 5-steroid isomerase.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Electrophoresis; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Pseudomonas; Steroid Isomerases | 1998 |
Mutations in HFE, the hemochromatosis candidate gene, in patients with NIDDM.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Diabetes Mellitus, Type 2; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Major Histocompatibility Complex; Membrane Proteins; Point Mutation; Reference Values; Tyrosine | 1998 |
Catalytic activity in Cephalosporium acremonium isopenicillin N synthase does not involve glutamine-234.
Topics: Acremonium; Amino Acid Substitution; Aspartic Acid; Binding Sites; Catalysis; Cloning, Molecular; DNA Primers; Glutamine; Histidine; Iron; Kinetics; Mutagenesis, Site-Directed; Oxidoreductases; Point Mutation; Recombinant Proteins | 1998 |
Mutant isolation of the Escherichia coli quinoprotein glucose dehydrogenase and analysis of crucial residues Asp-730 and His-775 for its function.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Escherichia coli; Glucose Dehydrogenases; Histidine; Kinetics; Magnesium; Molecular Sequence Data; Mutagenesis, Site-Directed; Sequence Alignment | 1998 |
Frequency of the HFE C282Y and H63D mutations in distinct ethnic groups living in Spain.
Topics: Alleles; Aspartic Acid; Cysteine; Ethnicity; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Membrane Proteins; Mutation; Roma; Spain; Tyrosine | 1998 |
Phosphorylation of the Spo0B response regulator phosphotransferase of the phosphorelay initiating development in Bacillus subtilis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Bacillus subtilis; Bacterial Proteins; DNA Primers; Histidine; Mutagenesis, Site-Directed; Phosphorylation; Phosphotransferases; Point Mutation; Polymerase Chain Reaction; Promoter Regions, Genetic; Recombinant Proteins; Repressor Proteins; Sigma Factor; Signal Transduction; Spores, Bacterial; Trans-Activators; Transcription Factors | 1998 |
The mechanism of adenosylmethionine-dependent activation of methionine synthase: a rapid kinetic analysis of intermediates in reductive methylation of Cob(II)alamin enzyme.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Aspartic Acid; Cobalt; Electron Transport; Enzyme Activation; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Methylation; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 | 1998 |
A single mutation that results in an Asp to His substitution and partial exon skipping in a family with congenital contractural arachnodactyly.
Topics: Aged; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Epidermal Growth Factor; Exons; Female; Fibrillin-2; Fibrillins; Histidine; Humans; Male; Marfan Syndrome; Microfilament Proteins; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Sequence Alignment; Sequence Deletion; Sequence Homology, Amino Acid; Transcription, Genetic | 1998 |
An Arabidopsis protein that interacts with the cytokinin-inducible response regulator, ARR4, implicated in the His-Asp phosphorylay signal transduction.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Cloning, Molecular; DNA-Binding Proteins; Histidine; Hybrid Cells; Molecular Sequence Data; Phosphorylation; Plant Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Signal Transduction; Substrate Specificity; Yeasts | 1998 |
Examination of the role of DNA polymerase proofreading in the mutator effect of miscoding tRNAs.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; DNA Polymerase III; DNA, Bacterial; Escherichia coli; Glycine; Histidine; Molecular Sequence Data; Mutagenesis; RNA, Transfer | 1998 |
Quantumchemical study of the catalytic triad in subtilisin: the influence of amino acid substitutions on enzymatic activity.
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Catalysis; Histidine; Models, Chemical; Serine; Serine Endopeptidases; Subtilisins | 1998 |
Activating a zymogen without proteolytic processing: mutation of Lys15 and Asn194 activates trypsinogen.
Topics: Animals; Aprotinin; Asparagine; Aspartic Acid; Cattle; Coumarins; Enzyme Activation; Enzyme Stability; Histidine; Hydrolysis; Lysine; Mutagenesis, Site-Directed; Oligopeptides; Peptide Fragments; Phenylalanine; Protein Conformation; Protein Processing, Post-Translational; Rats; Recombinant Fusion Proteins; Substrate Specificity; Trypsin; Trypsinogen | 1998 |
Autocatalytic activation of human legumain at aspartic acid residues.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Blotting, Western; Catalytic Domain; Cell Line; Cysteine; Cysteine Endopeptidases; Enzyme Activation; Expressed Sequence Tags; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Plant Proteins; Recombinant Fusion Proteins; Sequence Alignment; Substrate Specificity | 1998 |
A PCR-SSP method for detecting the His63Asp mutation in the HFE gene associated with hereditary haemochromatosis.
Topics: Amino Acid Substitution; Aspartic Acid; Chromosomes, Human, Pair 6; DNA Primers; Electrophoresis, Agar Gel; Genetic Testing; Hemochromatosis; Histidine; Humans; Point Mutation; Polymerase Chain Reaction | 1998 |
Posttranslational deamidation of proteins: the case of hemoglobin J Sardegna [alpha50(CD8)His-->Asn-->Asp].
Topics: Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; DNA; Electrophoresis, Cellulose Acetate; Hemoglobin J; Histidine; Humans; Isoelectric Focusing; Point Mutation; Protein Processing, Post-Translational; Sequence Analysis, DNA | 1999 |
His...Asp catalytic dyad of ribonuclease A: conformational stability of the wild-type, D121N, D121A, and H119A enzymes.
Topics: Alanine; Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Catalysis; Cattle; Enzyme Stability; Histidine; Hydrogen Bonding; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Protein Folding; Ribonuclease, Pancreatic | 1998 |
Site-directed mutagenesis of charged and potentially proton-carrying residues in the beta subunit of the proton-translocating nicotinamide nucleotide transhydrogenase from Escherichia coli. Characterization of the beta H91, beta D392, and beta K424 mutant
Topics: Aspartic Acid; Biological Transport; Catalysis; Conserved Sequence; Enzyme Activation; Escherichia coli; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Lysine; Magnesium Chloride; Mutagenesis, Site-Directed; NADP; NADP Transhydrogenases; Proton Pumps; Recombinant Proteins; Sodium Chloride | 1999 |
Role of the buried glutamate in the alpha-helical coiled coil domain of the macrophage scavenger receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Cattle; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Macrophages; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Conformation; Protein Structure, Secondary; Rabbits; Receptors, Immunologic; Receptors, Scavenger; Sequence Analysis; Valine | 1999 |
Analysis of mutations in exon 1 of the human thyrotropin receptor gene: high frequency of the D36H and P52T polymorphic variants.
Topics: Alleles; Amino Acid Substitution; Aspartic Acid; Exons; Female; Gene Frequency; Genetic Testing; Graves Disease; Heterozygote; Histidine; Humans; Male; Mutation; Polymorphism, Single-Stranded Conformational; Proline; Receptors, Thyrotropin; Restriction Mapping; Threonine | 1999 |
His ... Asp catalytic dyad of ribonuclease A: histidine pKa values in the wild-type, D121N, and D121A enzymes.
Topics: Animals; Aspartic Acid; Biophysical Phenomena; Biophysics; Catalytic Domain; Cattle; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Pancreas; Point Mutation; Protein Conformation; Ribonuclease, Pancreatic; Uridine Monophosphate | 1999 |
Histidine-containing phosphotransfer (HPt) signal transducers implicated in His-to-Asp phosphorelay in Arabidopsis.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Catalytic Domain; Chromosome Mapping; DNA-Binding Proteins; Escherichia coli; Fungal Proteins; Genes, Plant; Genetic Complementation Test; Histidine; Histidine Kinase; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Phosphotransferases; Plant Proteins; Protein Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Signal Transduction | 1998 |
Identification of residues essential for human paraoxonase (PON1) arylesterase/organophosphatase activities.
Topics: Amino Acids; Animals; Aryldialkylphosphatase; Aspartic Acid; Binding Sites; Bromosuccinimide; Calcium Radioisotopes; Cell Line; Dicyclohexylcarbodiimide; Diethyl Pyrocarbonate; Enzyme Activation; Enzyme Inhibitors; Esterases; Glutamic Acid; Glycosylation; Histidine; Humans; Indicators and Reagents; Kidney; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Rabbits; Recombinant Proteins; Spectrometry, Fluorescence; Terbium; Tryptophan | 1999 |
Structural analysis of phospholipase A2 from functional perspective. 1. Functionally relevant solution structure and roles of the hydrogen-bonding network.
Topics: Animals; Aspartic Acid; Calcium-Binding Proteins; Catalysis; Cattle; Crystallization; Crystallography, X-Ray; Histidine; Hydrogen Bonding; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phospholipases A; Phospholipases A2; Protein Structure, Secondary; Solutions; Structure-Activity Relationship; Swine; Tyrosine | 1999 |
Structural basis of substrate specificity in malate dehydrogenases: crystal structure of a ternary complex of porcine cytoplasmic malate dehydrogenase, alpha-ketomalonate and tetrahydoNAD.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Crystallography, X-Ray; Cytoplasm; Histidine; Malate Dehydrogenase; Malonates; Molecular Sequence Data; NAD; Protein Conformation; Protein Structure, Secondary; Substrate Specificity; Swine | 1999 |
Analysis of zinc binding sites in protein crystal structures.
Topics: Aspartic Acid; Binding Sites; Catalysis; Chlorine; Crystallography, X-Ray; Cysteine; Databases, Factual; Glutamine; Histidine; Models, Molecular; Molecular Conformation; Nitrogen; Oxygen; Protein Binding; Sulfur; Zinc | 1998 |
Crystallographic characterization of a novel protein SixA which exhibits phospho-histidine phosphatase activity in the multistep His-Asp phosphorelay.
Topics: Aspartic Acid; Bacterial Proteins; Crystallization; Crystallography, X-Ray; Escherichia coli; Escherichia coli Proteins; Histidine; Membrane Proteins; Phosphoric Monoester Hydrolases; Protein Kinases; Signal Transduction | 1999 |
Substitutions at histidine 74 and aspartate 278 alter ligand binding and allostery in lactose repressor protein.
Topics: Allosteric Regulation; Aspartic Acid; Bacterial Proteins; Binding, Competitive; Escherichia coli; Escherichia coli Proteins; Histidine; Hydrogen-Ion Concentration; Lac Repressors; Ligands; Models, Molecular; Mutagenesis; Protein Conformation; Repressor Proteins | 1999 |
Site-directed mutants of charged residues in the active site of tyrosine hydroxylase.
Topics: Amino Acid Substitution; Arginine; Aspartic Acid; Binding Sites; Conserved Sequence; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Mutagenesis, Site-Directed; Recombinant Proteins; Tyrosine 3-Monooxygenase | 1999 |
Double mutation (A171T and D444H) is a common cause of profound biotinidase deficiency in children ascertained by newborn screening the the United States. Mutations in brief no. 128. Online.
Topics: Acyltransferases; Alanine; Aspartic Acid; Histidine; Humans; Infant, Newborn; Mutation; Neonatal Screening; Threonine | 1998 |
Double-mutant analysis of the interaction of Ras with the Ras-binding domain of RGL.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Glutamic Acid; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Histidine; Humans; Lysine; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; ras Proteins; Rats; Recombinant Fusion Proteins; Static Electricity; Tyrosine | 1999 |
X-ray structure of the Escherichia coli periplasmic 5'-nucleotidase containing a dimetal catalytic site.
Topics: 5'-Nucleotidase; Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Escherichia coli; Histidine; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Phosphoric Monoester Hydrolases; Protein Conformation; Protein Structure, Secondary; Sequence Alignment; Sequence Homology, Amino Acid; Zinc | 1999 |
Hb Rio Claro [beta34(B16)Val-->Met]: a novel electrophoretically silent variant found in association with Hb Hasharon [alpha47(CE5)Asp-->His] and alpha-thalassemia-2(-alpha3.7).
Topics: Adult; alpha-Thalassemia; Aspartic Acid; Child, Preschool; Electrophoresis; Hemoglobins, Abnormal; Histidine; Humans; Male; Methionine; Point Mutation; Valine | 1999 |
A fission yeast gene (prr1(+)) that encodes a response regulator implicated in oxidative stress response.
Topics: Aspartic Acid; DNA-Binding Proteins; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Histidine; Mitogen-Activated Protein Kinases; Models, Biological; Molecular Sequence Data; Oxidative Stress; Phenotype; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Signal Transduction; Transcription Factors | 1999 |
Mechanistic studies of the folding of human lysozyme and the origin of amyloidogenic behavior in its disease-related variants.
Topics: Amyloid; Amyloidosis; Aspartic Acid; Histidine; Humans; Isoleucine; Kinetics; Mass Spectrometry; Models, Molecular; Muramidase; Protein Folding; Protons; Recombinant Proteins; Spectrometry, Fluorescence; Threonine | 1999 |
Consequences of breaking the Asp-His hydrogen bond of the catalytic triad: effects on the structure and dynamics of the serine esterase cutinase.
Topics: Aspartic Acid; Binding Sites; Carboxylic Ester Hydrolases; Catalysis; Computer Simulation; Esterases; Fusarium; Histidine; Hydrogen Bonding; Models, Molecular; Molecular Structure; Protein Conformation | 1999 |
Proton NMR investigation of the heme active site structure of an engineered cytochrome c peroxidase that mimics manganese peroxidase.
Topics: Arginine; Aspartic Acid; Binding Sites; Cyanides; Cytochrome-c Peroxidase; Glutamic Acid; Glycine; Heme; Histidine; Leucine; Molecular Mimicry; Nuclear Magnetic Resonance, Biomolecular; Peroxidases; Protein Engineering; Protons; Spectrophotometry; Valine | 1999 |
Specificity and catalysis of uracil DNA glycosylase. A molecular dynamics study of reactant and product complexes with DNA.
Topics: Aspartic Acid; Binding Sites; Catalysis; Computer Simulation; Crystallography, X-Ray; DNA; DNA Glycosylases; Histidine; Hydrolysis; Macromolecular Substances; Models, Chemical; Models, Molecular; Mutation; N-Glycosyl Hydrolases; Protein Conformation; Substrate Specificity; Thermodynamics; Uracil-DNA Glycosidase | 1999 |
The aspartyl replacement of the active site histidine in histidine-containing protein, HPr, of the Escherichia coli Phosphoenolpyruvate:Sugar phosphotransferase system can accept and donate a phosphoryl group. Spontaneous dephosphorylation of acyl-phospha
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Binding Sites; Crystallization; Enzyme Stability; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Protein Structure, Tertiary; Recombinant Proteins | 1999 |
Evidence for a direct interaction between the penultimate aspartic acid of cholecystokinin and histidine 207, located in the second extracellular loop of the cholecystokinin B receptor.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Cholecystokinin; COS Cells; Histidine; Mutagenesis, Site-Directed; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Structure-Activity Relationship | 1999 |
Characterization of residues in human IgE and IgG binding site by chemical modification of ovomucoid third domain.
Topics: Acylation; Alkylation; Aspartic Acid; Binding Sites; Child, Preschool; Circular Dichroism; Female; Glutamic Acid; Histidine; Humans; Immunoglobulin E; Immunoglobulin G; Infant; Lysine; Ovomucin; Protein Structure, Secondary; Structure-Activity Relationship; Tetranitromethane; Tyrosine | 1999 |
Engineering cytochrome c peroxidase into cytochrome P450: a proximal effect on heme-thiolate ligation.
Topics: Aspartic Acid; Circular Dichroism; Cysteine; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome-c Peroxidase; Cytochromes c; Electron Spin Resonance Spectroscopy; Escherichia coli; Ferric Compounds; Heme; Histidine; Imidazoles; Leucine; Ligands; Mutagenesis, Site-Directed; Protein Engineering; Spectrophotometry, Ultraviolet | 1999 |
Extracellular glutamate in the dorsal horn of the lumbar spinal cord in the freely moving rat during hindlimb stepping.
Topics: Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Extracellular Space; Female; Glutamic Acid; Hindlimb; Histidine; Locomotion; Microdialysis; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Spinal Cord | 1999 |
M-side electron transfer in reaction center mutants with a lysine near the nonphotoactive bacteriochlorophyll.
Topics: Amino Acid Substitution; Anions; Aspartic Acid; Bacteriochlorophylls; Benzoquinones; Electron Transport; Histidine; Kinetics; Light-Harvesting Protein Complexes; Lysine; Mutagenesis, Site-Directed; Pheophytins; Photochemistry; Photosynthetic Reaction Center Complex Proteins; Rhodobacter capsulatus; Spectrum Analysis | 1999 |
Increasing protein stability by altering long-range coulombic interactions.
Topics: Aspartic Acid; Electrochemistry; Histidine; Hydrogen-Ion Concentration; Protein Conformation; Protein Denaturation; Proteins; Recombinant Proteins; Ribonuclease T1; Static Electricity; Thermodynamics; Urea | 1999 |
Compilation and characterization of Arabidopsis thaliana response regulators implicated in His-Asp phosphorelay signal transduction.
Topics: Amino Acid Sequence; Arabidopsis; Aspartic Acid; Base Sequence; DNA Primers; Genes, Plant; Histidine; Molecular Sequence Data; Plant Proteins; Sequence Homology, Amino Acid; Signal Transduction | 1999 |
Role of electrophilic and general base catalysis in the mechanism of Escherichia coli uracil DNA glycosylase.
Topics: Asparagine; Aspartic Acid; Binding Sites; Catalysis; Deuterium Oxide; DNA Glycosylases; Escherichia coli; Glutamine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Solvents; Substrate Specificity; Uracil; Uracil-DNA Glycosidase | 1999 |
Amplification of signaling activity of the arc two-component system of Escherichia coli by anaerobic metabolites. An in vitro study with different protein modules.
Topics: Acetates; Anaerobiosis; Aspartic Acid; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cell Membrane; Escherichia coli; Escherichia coli Proteins; Fermentation; Histidine; Kinetics; Lactates; Membrane Proteins; Oxidation-Reduction; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinases; Pyruvates; Repressor Proteins; Signal Transduction | 1999 |
His-Asp phosphotransfer possibly involved in the nitrogen signal transduction mediated by cytokinin in maize: molecular cloning of cDNAs for two-component regulatory factors and demonstration of phosphotransfer activity in vitro.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Blotting, Northern; Cloning, Molecular; Cytokinins; DNA, Complementary; Gene Expression Regulation, Plant; Histidine; Molecular Sequence Data; Nitrogen; Phosphorylation; Plant Leaves; Plant Proteins; Protein Structure, Tertiary; RNA, Plant; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Signal Transduction; Tissue Distribution; Zea mays; Zeatin | 1999 |
A conserved His-Asp signal response regulator-like gene in Heterosigma akashiwo chloroplasts.
Topics: Algal Proteins; Amino Acid Sequence; Aspartic Acid; Cell Cycle; Chloroplasts; Conserved Sequence; DNA, Chloroplast; Eukaryota; Gene Expression Regulation; Histidine; Molecular Sequence Data; Phosphorylation; RNA; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Signal Transduction; Transcription Factors; Transcription, Genetic | 1999 |
Identification and molecular characterization of the new alpha-1-antitrypsin deficient allele PI Y barcelona (Asp256-->Val and Pro391-->His). Mutations in brief no. 174. Online.
Topics: Alleles; alpha 1-Antitrypsin Deficiency; Amino Acid Substitution; Aspartic Acid; Histidine; Humans; Phenotype; Proline; Valine | 1998 |
Adult and fetal haemoglobin J-Sardegna [alpha50(CE8)His-->Asp]: functional and molecular modelling studies.
Topics: 2,3-Diphosphoglycerate; Adult; Aging; Amino Acid Substitution; Arginine; Aspartic Acid; Binding Sites; Computer Simulation; Crystallography, X-Ray; Fetal Blood; Genetic Variation; Hemoglobin J; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Models, Molecular; Oxygen; Temperature; Thermodynamics; Time Factors | 2000 |
Selectively 2H-labeled Glu/Asp: application to pKa measurements in Abeta amyloid peptides.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Aspartic Acid; Deuterium; Glutamic Acid; Histidine; Isotope Labeling; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptide Fragments; Protein Conformation | 2000 |
Natural poly-histidine affinity tag for purification of recombinant proteins on cobalt(II)-carboxymethylaspartate crosslinked agarose.
Topics: Affinity Labels; Amino Acid Sequence; Aspartic Acid; Base Sequence; Chloramphenicol O-Acetyltransferase; Chromatography, Affinity; Cloning, Molecular; Cross-Linking Reagents; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genetic Vectors; Green Fluorescent Proteins; Histidine; Luminescent Proteins; Molecular Sequence Data; Peptides; Protein Denaturation; Recombinant Proteins; Sepharose; Tetrahydrofolate Dehydrogenase | 1999 |
A genomic analysis of two-component signal transduction in Streptococcus pneumoniae.
Topics: Animals; Aspartic Acid; Bacterial Proteins; Genome, Bacterial; Histidine; Histidine Kinase; Male; Methyltransferases; Mice; Mice, Inbred CBA; Mutagenesis; Phylogeny; Pneumococcal Infections; Protein Kinases; Respiratory Tract Infections; Signal Transduction; Streptococcus pneumoniae | 2000 |
Purification of recombinant hydantoinase and L-N-carbamoylase from Arthrobacter aurescens expressed in Escherichia coli: comparison of wild-type and genetically modified proteins.
Topics: Amidohydrolases; Arthrobacter; Aspartic Acid; Base Sequence; DNA Primers; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Recombinant Proteins | 2000 |
Slow formation of [3Fe-4S](1+) clusters in mutant forms of Desulfovibrio africanus ferredoxin III.
Topics: Amino Acid Substitution; Aspartic Acid; Desulfovibrio; Electron Spin Resonance Spectroscopy; Ferredoxins; Genetic Variation; Glutamic Acid; Histidine; Iron-Sulfur Proteins; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Recombinant Proteins; Spectrophotometry | 2000 |
Evidence for the rate of the final step in the bacteriorhodopsin photocycle being controlled by the proton release group: R134H mutant.
Topics: Arginine; Aspartic Acid; Bacteriorhodopsins; Darkness; Halobacterium salinarum; Histidine; Hydrogen-Ion Concentration; Kinetics; Light; Mutagenesis, Site-Directed; Photolysis; Protons; Purple Membrane | 2000 |
Histidine to aspartate phosphotransferase activity of nm23 proteins: phosphorylation of aldolase C on Asp-319.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Brain; Cattle; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Fructose-Bisphosphate Aldolase; Histidine; Humans; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Muscles; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Phosphorylation; Phosphotransferases; Rabbits; Rats; Sequence Homology, Amino Acid; Sodium Cholate; Transcription Factors | 2000 |
Variable zinc coordination in endostatin.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Collagen; Collagen Type XVIII; Crystallography, X-Ray; Dimerization; Endostatins; Histidine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Protein Conformation; Solutions; Structure-Activity Relationship; Zinc | 2000 |
Clinical characteristics of type 2 diabetes in patients with mutations of HFE.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Diabetes Mellitus, Type 2; Female; Ferritins; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Insulin Resistance; Iron; Major Histocompatibility Complex; Male; Membrane Proteins; Middle Aged; Point Mutation; Transferrin; Tyrosine | 2000 |
Roles of his205, his296, his303 and Asp259 in catalysis by NAD+-specific D-lactate dehydrogenase.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Binding Sites; Catalysis; Histidine; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Lactobacillus; Models, Molecular; Mutagenesis, Site-Directed; NAD; Point Mutation; Recombinant Fusion Proteins; Structure-Activity Relationship | 2000 |
The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: hydration and sterochemical analysis.
Topics: Amides; Amino Acid Sequence; Animals; Anisotropy; Aspartic Acid; Binding Sites; Cattle; Crystallization; Crystallography, X-Ray; Glutamine; Histidine; Hydrogen; Hydrogen Bonding; Lysine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Ribonuclease, Pancreatic; Solvents; Sulfates; Water | 2000 |
Functional analysis of conserved aspartate and histidine residues located around the type 2 copper site of copper-containing nitrite reductase.
Topics: Alcaligenes; Amino Acid Sequence; Aspartic Acid; Binding Sites; Conserved Sequence; Copper; Histidine; Kinetics; Molecular Sequence Data; Mutation; Nitrite Reductases; Recombinant Proteins; Structure-Activity Relationship | 2000 |
The SixA phospho-histidine phosphatase modulates the ArcB phosphorelay signal transduction in Escherichia coli.
Topics: Anaerobiosis; Aspartic Acid; Bacterial Outer Membrane Proteins; Bacterial Proteins; Dimethyl Sulfoxide; Electron Transport; Escherichia coli; Escherichia coli Proteins; Fumarates; Genes, Bacterial; Genes, Reporter; Histidine; Kinetics; Membrane Proteins; Methylamines; Mutation; Nitrates; Oxygen; Phosphorylation; Protein Kinases; Protein Structure, Tertiary; Recombinant Fusion Proteins; Repressor Proteins; Signal Transduction | 2000 |
Investigation of spectroscopic intermediates during copper-binding and TPQ formation in wild-type and active-site mutants of a copper-containing amine oxidase from yeast.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Binding Sites; Coenzymes; Copper; Cysteine; Dihydroxyphenylalanine; Glutamic Acid; Glutamine; Histidine; Mutagenesis, Site-Directed; Oxygen Consumption; Pichia; Recombinant Proteins; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet | 2000 |
Rhamnogalacturonan acetylesterase elucidates the structure and function of a new family of hydrolases.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetylesterase; Amino Acid Sequence; Aspartic Acid; Carbohydrate Sequence; Catalytic Domain; Crystallography, X-Ray; Esterases; Histidine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Phospholipases A; Protein Conformation; Protein Folding; Sequence Homology, Amino Acid | 2000 |
Manganese selectivity of pmr1, the yeast secretory pathway ion pump, is defined by residue gln783 in transmembrane segment 6. Residue Asp778 is essential for cation transport.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Aspartic Acid; ATP-Binding Cassette Transporters; Binding Sites; Calcium-Transporting ATPases; Cations, Divalent; Egtazic Acid; Fungal Proteins; Glutamine; Histidine; Ion Pumps; Manganese; Models, Molecular; Molecular Chaperones; Molecular Sequence Data; Mutation; Peptides; Phosphoproteins; Phosphorylation; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2000 |
Deterministic features of side-chain main-chain hydrogen bonds in globular protein structures.
Topics: Amino Acids; Asparagine; Aspartic Acid; Crystallization; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Protein Conformation; Protein Structure, Secondary; Proteins; Serine; Threonine | 2000 |
Catalytic roles for two water bridged residues (Asp-98 and His-255) in the active site of copper-containing nitrite reductase.
Topics: Alcaligenes; Aspartic Acid; Catalysis; Catalytic Domain; Copper; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Histidine; Hydrogen Bonding; Models, Molecular; Mutation; Nitrite Reductases; Water | 2000 |
Conserved serine and histidine residues are critical for activity of the ER-type signal peptidase SipW of Bacillus subtilis.
Topics: Amino Acid Sequence; Archaeal Proteins; Aspartic Acid; Bacillus subtilis; Bacterial Proteins; Binding Sites; Blotting, Western; Catalysis; Cell Fractionation; Conserved Sequence; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Histidine; Membrane Proteins; Models, Biological; Molecular Sequence Data; Peptide Hydrolases; Plasmids; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Spores | 2000 |
Identification of key amino acid residues in Neisseria polysaccharea amylosucrase.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Base Sequence; Binding Sites; Catalysis; Glucosyltransferases; Glutamic Acid; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Neisseria; Sequence Alignment; Structure-Activity Relationship | 2000 |
Mutational evidence supporting the involvement of tripartite residues His183, Asp185, and His243 in Streptomyces clavuligerus deacetoxycephalosporin C synthase for catalysis.
Topics: Aspartic Acid; Catalysis; Catalytic Domain; Gene Expression; Histidine; Intramolecular Transferases; Mutagenesis, Site-Directed; Penicillin-Binding Proteins; Protein Structure, Secondary; Solubility; Streptomyces | 2000 |
Pyruvate dehydrogenase kinase from Arabidopsis thaliana: a protein histidine kinase that phosphorylates serine residues.
Topics: Alanine; Amino Acid Sequence; Arabidopsis; Aspartic Acid; DNA, Complementary; Glutamine; Histidine; Histidine Kinase; Kinetics; Mitochondria; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphoamino Acids; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Trypsin; Zea mays | 2000 |
Identification of a polymorphism (D366H) in the endoglin gene in Chinese.
Topics: Amino Acid Substitution; Antigens, CD; Aspartic Acid; China; Chromosomes, Human, Pair 9; Endoglin; Histidine; Humans; Polymorphism, Genetic; Receptors, Cell Surface; Telangiectasia, Hereditary Hemorrhagic; Vascular Cell Adhesion Molecule-1 | 2000 |
Structural basis for the feedback regulation of Escherichia coli pantothenate kinase by coenzyme A.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Amino Acid Sequence; Arginine; Aspartic Acid; Binding Sites; Coenzyme A; Crystallography, X-Ray; Dimerization; Escherichia coli; Feedback; Histidine; Ligands; Molecular Sequence Data; Phosphotransferases (Alcohol Group Acceptor); Protein Structure, Secondary | 2000 |
Structure of arylamine N-acetyltransferase reveals a catalytic triad.
Topics: Acetanilides; Amino Acid Sequence; Arylamine N-Acetyltransferase; Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Histidine; Models, Molecular; Molecular Sequence Data; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Salmonella typhimurium; Sequence Alignment; Structure-Activity Relationship | 2000 |
Kinetic and structural characterization of urease active site variants.
Topics: Aspartic Acid; Base Sequence; Catalytic Domain; Crystallography, X-Ray; DNA Primers; Escherichia coli; Genetic Variation; Histidine; Hydrogen-Ion Concentration; Kinetics; Klebsiella; Models, Chemical; Mutagenesis, Site-Directed; Recombinant Proteins; Urease; Water | 2000 |
Molecular basis for complex formation between methylamine dehydrogenase and amicyanin revealed by inverse mutagenesis of an interprotein salt bridge.
Topics: Amino Acid Substitution; Arginine; Aspartic Acid; Bacterial Proteins; Histidine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Oxidoreductases Acting on CH-NH Group Donors; Protein Conformation; Recombinant Proteins; Structure-Activity Relationship; Thermodynamics | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Possible His to Asp phosphorelay signaling in an Arabidopsis two-component system.
Topics: Arabidopsis; Aspartic Acid; Binding Sites; DNA, Complementary; Genes, Plant; Histidine; Histidine Kinase; Models, Biological; Mutation; Plant Proteins; Protein Binding; Protein Kinases; Signal Transduction; Two-Hybrid System Techniques | 2000 |
Mechanism of pH-dependent N-acetylgalactosamine binding by a functional mimic of the hepatocyte asialoglycoprotein receptor.
Topics: Acetylgalactosamine; Amino Acids; Arginine; Asialoglycoprotein Receptor; Aspartic Acid; Calcium; Carrier Proteins; Crystallography, X-Ray; Escherichia coli; Galactose; Glycine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Liver; Mannose-Binding Lectin; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Receptors, Cell Surface; Tyrosine; Water | 2000 |
Genes encoding pseudo-response regulators: insight into His-to-Asp phosphorelay and circadian rhythm in Arabidopsis thaliana.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Circadian Rhythm; Gene Transfer Techniques; Genes, Plant; Green Fluorescent Proteins; Histidine; Luminescent Proteins; Molecular Sequence Data; Onions; Phosphorylation; Plant Growth Regulators; Plant Proteins; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Transcription Factors; Zinc Fingers | 2000 |
Tuning of the porin expression under anaerobic growth conditions by his-to-Asp cross-phosphorelay through both the EnvZ-osmosensor and ArcB-anaerosensor in Escherichia coli.
Topics: Anaerobiosis; Aspartic Acid; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Galactosidase; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Gene Expression; Genetic Complementation Test; Genetic Vectors; Histidine; Membrane Proteins; Multienzyme Complexes; Phosphorylation; Porins; Protein Kinases; Recombinant Proteins; Signal Transduction; Water-Electrolyte Balance | 2000 |
A different function for a critical tryptophan in c-Raf and Hck.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; COS Cells; Enzyme Activation; Histidine; Lysine; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Mutagenesis; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Proto-Oncogene Proteins c-raf; Sequence Analysis; Tryptophan | 2000 |
Functional analysis of the active site of a metallo-beta-lactamase proliferating in Japan.
Topics: Anti-Bacterial Agents; Apoenzymes; Aspartic Acid; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Binding Sites; Binding, Competitive; Cysteine; Dose-Response Relationship, Drug; Escherichia coli; Histidine; Humans; Japan; Kinetics; Klebsiella pneumoniae; Ligands; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Zinc | 2000 |
Structure-function studies of the non-heme iron active site of isopenicillin N synthase: some implications for catalysis.
Topics: Amino Acid Substitution; Aspartic Acid; Binding Sites; Catalysis; Histidine; Iron; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Nonheme Iron Proteins; Oxidoreductases; Protein Binding; Streptomyces; Structure-Activity Relationship | 2000 |
Swarming of Pseudomonas aeruginosa is dependent on cell-to-cell signaling and requires flagella and pili.
Topics: Aspartic Acid; Bacterial Proteins; Culture Media; Decanoates; Disaccharides; DNA-Binding Proteins; Fimbriae Proteins; Fimbriae, Bacterial; Flagella; Flagellin; Glutamic Acid; Histidine; Microscopy, Electron; Movement; Mutation; Nitrogen; Proline; Pseudomonas aeruginosa; Rhamnose; Signal Transduction; Surface-Active Agents; Trans-Activators; Transcription Factors | 2000 |
Identification of the histidine and aspartic acid residues essential for enzymatic activity of a family I.3 lipase by site-directed mutagenesis.
Topics: Amino Acid Substitution; Aspartic Acid; Binding Sites; Catalytic Domain; Circular Dichroism; Esterases; Histidine; Lipase; Mutagenesis, Site-Directed; Mutation; Pseudomonas | 2000 |
Enhancement of the enzymatic activity of ribonuclease HI from Thermus thermophilus HB8 with a suppressor mutation method.
Topics: Amino Acid Substitution; Aspartic Acid; Circular Dichroism; DNA Mutational Analysis; Enzyme Activation; Enzyme Stability; Genes, Bacterial; Genes, Suppressor; Genetic Complementation Test; Histidine; Mutagenesis, Site-Directed; Point Mutation; Ribonuclease H; Thermodynamics; Thermus thermophilus | 2000 |
An examination of the role of asp-177 in the His-Asp catalytic dyad of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase: X-ray structure and pH dependence of kinetic parameters of the D177N mutant enzyme.
Topics: Aspartic Acid; Catalytic Domain; Crystallography, X-Ray; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Leuconostoc; Models, Chemical; Models, Molecular; Movement; Mutagenesis, Site-Directed; Mutation | 2000 |
Characterization of the Co(2+) and Ni(2+) binding amino-acid residues of the N-terminus of human albumin. An insight into the mechanism of a new assay for myocardial ischemia.
Topics: Alanine; Albumins; Aspartic Acid; Chromatography, Liquid; Cobalt; Histidine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metalloendopeptidases; Myocardial Ischemia; Nickel; Peptides; Protein Conformation | 2001 |
Role of the conserved acidic residue Asp21 in the structure of phosphatidylinositol 3-kinase Src homology 3 domain: circular dichroism and nuclear magnetic resonance studies.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Circular Dichroism; Conserved Sequence; Histidine; Humans; Kinetics; Ligands; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Phenylalanine; Phosphatidylinositol 3-Kinases; Protein Conformation; src Homology Domains; Tyrosine | 2001 |
Site-directed mutagenesis of the bacterial metalloamidase UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC). Identification of the zinc binding site.
Topics: Alanine; Amidohydrolases; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Binding Sites; Cations, Divalent; Conserved Sequence; Escherichia coli; Glutamic Acid; Gram-Negative Bacteria; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Zinc | 2001 |
Two types of putative nuclear factors that physically interact with histidine-containing phosphotransfer (Hpt) domains, signaling mediators in His-to-Asp phosphorelay, in Arabidopsis thaliana.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Aspartic Acid; beta-Galactosidase; Carrier Proteins; Catalytic Domain; DNA-Binding Proteins; Fungal Proteins; Genes, Plant; Genetic Complementation Test; Histidine; Histidine Kinase; Intracellular Signaling Peptides and Proteins; Microtubule-Associated Proteins; Molecular Sequence Data; Nuclear Proteins; Periplasmic Binding Proteins; Phosphorylation; Phosphotransferases; Plant Proteins; Protein Kinases; Proteins; Saccharomyces cerevisiae; Signal Transduction; t-Complex Genome Region; Transcription Factors; Ubiquitin-Protein Ligases | 2001 |
Direct evidence for the protonation of aspartate-75, proposed to be at a quinol binding site, upon reduction of cytochrome bo3 from Escherichia coli.
Topics: Amides; Aspartic Acid; Binding Sites; Cytochrome b Group; Cytochromes; Electrochemistry; Electron Transport Complex IV; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Histidine; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Protons; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Ubiquinone | 2001 |
Bioelectronic detection of point mutations using discrimination of the H63D polymorphism of the Hfe gene as a model.
Topics: Amino Acid Substitution; Aspartic Acid; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Membrane Proteins; Oligonucleotide Array Sequence Analysis; Pilot Projects; Point Mutation; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide | 2000 |
Compilation and characterization of histidine-containing phosphotransmitters implicated in His-to-Asp phosphorelay in plants: AHP signal transducers of Arabidopsis thaliana.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Cell Cycle Proteins; Histidine; Histidine Kinase; Molecular Sequence Data; Phosphotransferases; Plant Proteins; Protein Kinases; Schizosaccharomyces pombe Proteins; Sequence Homology, Amino Acid; Signal Transduction | 2000 |
Haemochromatosis: automated detection of the two point mutations in the HFE gene: Cys282Tyr and His63Asp.
Topics: Aspartic Acid; Cysteine; DNA Mutational Analysis; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Membrane Proteins; Mutation; Point Mutation; Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity; Tyrosine | 2000 |
Zinc and copper bind to unique sites of histatin 5.
Topics: Aspartic Acid; Copper; Glutamic Acid; Histatins; Histidine; Humans; Ligands; Magnetic Resonance Spectroscopy; Protein Binding; Salivary Proteins and Peptides; Zinc | 2001 |
Copurification of the Lac repressor with polyhistidine-tagged proteins in immobilized metal affinity chromatography.
Topics: Aspartic Acid; Bacterial Proteins; Biotinylation; Chromatography, Affinity; Cobalt; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; GTP Phosphohydrolases; Histidine; Lac Operon; Lac Repressors; Mass Spectrometry; Models, Molecular; Molecular Weight; Operator Regions, Genetic; Peptide Mapping; Peptides; Phosphoproteins; Protein Structure, Quaternary; Recombinant Fusion Proteins; Repressor Proteins; Sepharose | 2001 |
[Type I protein C deficiency caused by a novel protein C gene mutation].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antithrombin III; Aspartic Acid; Histidine; Humans; Middle Aged; Pedigree; Point Mutation; Protein C; Protein C Deficiency | 1998 |
Structure of a serine protease proteinase K from Tritirachium album limber at 0.98 A resolution.
Topics: Ascomycota; Aspartic Acid; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Endopeptidase K; Fungal Proteins; Histidine; Hydrogen Bonding; Models, Molecular; Protein Conformation; Solvents | 2001 |
Investigations of the alkaline and acid transitions of umecyanin, a stellacyanin from horseradish roots.
Topics: Aspartic Acid; Binding Sites; Brassicaceae; Cucurbitaceae; Electrochemistry; Histidine; Hydrogen-Ion Concentration; Metalloproteins; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Plant Proteins; Plant Roots; Protons; Rosales; Spectrophotometry, Ultraviolet | 2001 |
Biochemical analysis of point mutations in the 5'-3' exonuclease of DNA polymerase I of Streptococcus pneumoniae. Functional and structural implications.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Conserved Sequence; DNA; DNA Polymerase I; DNA, Single-Stranded; Dose-Response Relationship, Drug; Exodeoxyribonuclease V; Exodeoxyribonucleases; Glutamic Acid; Histidine; Kinetics; Ligands; Magnesium Chloride; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Plasmids; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Streptococcus pneumoniae | 2001 |
Deuterium isotope effects during carbon-hydrogen bond cleavage by trimethylamine dehydrogenase. Implications for mechanism and vibrationally assisted hydrogen tunneling in wild-type and mutant enzymes.
Topics: Aspartic Acid; Carbon; Deuterium; Flavins; Histidine; Hot Temperature; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Methylamines; Models, Chemical; Oxidoreductases, N-Demethylating; Tyrosine | 2001 |
Eubacterial arylamine N-acetyltransferases - identification and comparison of 18 members of the protein family with conserved active site cysteine, histidine and aspartate residues.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arylamine N-Acetyltransferase; Aspartic Acid; Bacterial Proteins; Blotting, Western; Catalytic Domain; Conserved Sequence; Cysteine; Enterobacteriaceae; Gram-Positive Bacteria; Histidine; Models, Molecular; Molecular Sequence Data; Operon; Polymerase Chain Reaction; Polymorphism, Genetic; Proteobacteria; Sequence Alignment; Substrate Specificity | 2001 |
Molecular characterization of a subtilase from the vascular wilt fungus Fusarium oxysporum.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Fusarium; Green Fluorescent Proteins; Histidine; Kinetics; Luminescent Proteins; Mitochondria; Molecular Sequence Data; Plant Diseases; Polygalacturonase; Polymerase Chain Reaction; Promoter Regions, Genetic; Recombinant Fusion Proteins; Restriction Mapping; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Solanum lycopersicum; Subtilisins; Virulence | 2001 |
Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase of riboflavin biosynthesis.
Topics: Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Dimerization; Escherichia coli; Glutamic Acid; Histidine; Intramolecular Transferases; Magnesium; Models, Chemical; Models, Molecular; Protein Structure, Secondary; Riboflavin; Riboflavin Synthase | 2001 |
Characterization of mutants of beta histidine91, beta aspartate213, and beta asparagine222, possible components of the energy transduction pathway of the proton-translocating pyridine nucleotide transhydrogenase of Escherichia coli.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Aspartic Acid; Binding Sites; Energy Metabolism; Escherichia coli; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; NADP; NADP Transhydrogenases; Oxidation-Reduction; Protein Conformation | 2001 |
Electrically induced release of labelled taurine, alpha- and beta-alanine, glycine, glutamate and other amino acids from rat neocortical slices in vitro.
Topics: Alanine; Animals; Aspartic Acid; Carnosine; Electric Stimulation; Glutamic Acid; Glycine; Histidine; Neocortex; Neurons; Organ Culture Techniques; Rats; Serine; Taurine; Tritium | 1976 |
Active site residues of glutamate racemase.
Topics: Amino Acid Isomerases; Amino Acid Sequence; Asparagine; Aspartic Acid; Bacterial Proteins; Binding Sites; Deuterium; Glutamic Acid; Glutamine; Histidine; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Alignment | 2001 |
Association studies between haemochromatosis gene mutations and the risk of cardiovascular diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arteriosclerosis; Aspartic Acid; Brain Infarction; Cardiovascular Diseases; Case-Control Studies; Cysteine; Female; France; Genetic Predisposition to Disease; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Male; Membrane Proteins; Middle Aged; Mutation; Myocardial Infarction; Northern Ireland; Polymorphism, Genetic; Prevalence; Prospective Studies; Tyrosine; Ultrasonography; United Kingdom | 2001 |
Identification of essential residues for catalysis of rat intestinal phospholipase B/lipase.
Topics: Amino Acids; Animals; Aspartic Acid; Catalytic Domain; COS Cells; Enzyme Activation; Glycine; Guinea Pigs; Histidine; Intestines; Lysophospholipase; Mutagenesis, Site-Directed; Rabbits; Rats; Repetitive Sequences, Amino Acid; Serine; Threonine | 2001 |
Catalytic acid-base groups in yeast pyruvate decarboxylase. 1. Site-directed mutagenesis and steady-state kinetic studies on the enzyme with the D28A, H114F, H115F, and E477Q substitutions.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Carbon Dioxide; Catalysis; Catalytic Domain; Cloning, Molecular; DNA, Recombinant; Enzyme Activation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Pyruvate Decarboxylase; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity; Thiamine Pyrophosphate | 2001 |
Active-site mutations impairing the catalytic function of the catalytic subunit of human protein phosphatase 2A permit baculovirus-mediated overexpression in insect cells.
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Baculoviridae; Binding Sites; Catalysis; Cell Line; Histidine; Humans; Kinetics; Mutagenesis, Site-Directed; Phosphoprotein Phosphatases; Protein Phosphatase 2; Protein Subunits; Recombinant Proteins; Spodoptera; Transfection | 2001 |
Alternate substrate binding modes to two mutant (D98N and H255N) forms of nitrite reductase from Alcaligenes faecalis S-6: structural model of a transient catalytic intermediate.
Topics: Alcaligenes; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Copper; Crystallization; Crystallography, X-Ray; Histidine; Hydrogen Bonding; Models, Molecular; Mutagenesis, Site-Directed; Nitrite Reductases; Nitrites; Oxidation-Reduction; Substrate Specificity | 2001 |
beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Chromatography; Cysteine; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myristic Acid; Plasmids; Protein Binding; Recombinant Proteins | 2001 |
The Hemophilus influenzae Hap autotransporter is a chymotrypsin clan serine protease and undergoes autoproteolysis via an intermolecular mechanism.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Outer Membrane Proteins; Binding Sites; Biological Transport; Catalysis; Catalytic Domain; Chymotrypsin; Conserved Sequence; Genetic Techniques; Haemophilus influenzae; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Time Factors | 2001 |
The srhSR gene pair from Staphylococcus aureus: genomic and proteomic approaches to the identification and characterization of gene function.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Databases as Topic; Gene Deletion; Genes, Bacterial; Genomics; Histidine; Histidine Kinase; Kinetics; Mass Spectrometry; Molecular Sequence Data; Open Reading Frames; Peptide Library; Protein Kinases; Proteome; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Staphylococcus aureus | 2001 |
Adsorption of monomers on microspherical structures of thermal heterocomplex molecules from amino acids.
Topics: Adenine; Adsorption; Amino Acids; Aspartic Acid; Evolution, Chemical; Histidine; Hot Temperature; Hydrogen-Ion Concentration; Microspheres; Nucleosides; Proline; Pyrimidinones; Static Electricity; Suspensions | 1995 |
Hemochromatosis gene variants in patients with cardiomyopathy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Cardiomyopathies; Cysteine; Disease Progression; Female; Genotype; Heart Failure; Hemochromatosis; Histidine; Humans; Logistic Models; Male; Middle Aged; Mutation, Missense; Prognosis; Tyrosine | 2001 |
Substitution of aspartate and glutamate for active center histidines in the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system maintain phosphotransfer potential.
Topics: Aspartic Acid; Bacterial Proteins; Escherichia coli; Glutamic Acid; Histidine; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Structure-Activity Relationship | 2001 |
Hydrophobic amino acid residues in the acceptor binding site are main determinants for reaction mechanism and specificity of cyclodextrin-glycosyltransferase.
Topics: Amino Acids; Aspartic Acid; beta-Cyclodextrins; Binding Sites; Cyclodextrins; Dose-Response Relationship, Drug; Escherichia coli; Glucosyltransferases; Glutamic Acid; Histidine; Hydrolysis; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Plasmids; Protein Binding; Protein Conformation; Substrate Specificity; Water | 2001 |
The distal hinge of the reactive site loop and its proximity: a target to modulate plasminogen activator inhibitor-1 activity.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Arginine; Aspartic Acid; Binding Sites; DNA; Epitopes; Glutamic Acid; Histidine; Humans; Kinetics; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Plasminogen Activator Inhibitor 1; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Surface Plasmon Resonance; Swine; Time Factors | 2001 |
Crystal structure of the outer membrane protease OmpT from Escherichia coli suggests a novel catalytic site.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Histidine; Lipopolysaccharides; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine Endopeptidases | 2001 |
C282Y and H63D mutations in the HFE gene have no effect on iron overload disorders in Japan.
Topics: Adult; Asian People; Aspartic Acid; Cysteine; Female; Hemochromatosis; Hemochromatosis Protein; Hepatitis C, Chronic; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Iron Overload; Japan; Liver Diseases; Male; Membrane Proteins; Middle Aged; Point Mutation; Polymerase Chain Reaction; Tyrosine | 2001 |
Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Amyloidosis; Asparagine; Aspartic Acid; Chromatography, Gel; Circular Dichroism; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Microscopy, Electron; Molecular Sequence Data; Mutation; Peptide Fragments; Protein Folding; Protein Structure, Quaternary; Protein Structure, Secondary | 2001 |
Cellular localization of the signaling components of Arabidopsis His-to-Asp phosphorelay.
Topics: Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Cell Nucleus; Green Fluorescent Proteins; Histidine; Luminescent Proteins; Molecular Biology; Nuclear Proteins; Phosphotransferases; Plant Proteins; Recombinant Proteins; Repressor Proteins; Signal Transduction | 2001 |
The frequency of C282Y and H63D mutations in Hemochromatosis gene in native Estonians.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Aspartic Acid; Cysteine; DNA Mutational Analysis; DNA Primers; Estonia; Female; Gene Frequency; Genotype; Hemochromatosis; Histidine; Humans; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Tyrosine | 2001 |
Population screening for HFE-associated haemochromatosis.
Topics: Aspartic Acid; Australia; Genetic Testing; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Male; Membrane Proteins; Middle Aged; Sibling Relations | 2001 |
The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases.
Topics: Amino Acid Sequence; Aspartic Acid; Bacillus subtilis; Bacterial Proteins; Catalytic Domain; Conserved Sequence; Histidine; Lysine; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Signal Transduction; Spores, Bacterial; Transcription Factors | 2002 |
Residues 137 and 153 at the N terminus of the XylS protein influence the effector profile of this transcriptional regulator and the sigma factor used by RNA polymerase to stimulate transcription from its cognate promoter.
Topics: Amino Acids; Asparagine; Aspartic Acid; Bacterial Proteins; beta-Galactosidase; DNA; DNA-Binding Proteins; DNA-Directed RNA Polymerases; Escherichia coli; Glutamic Acid; Histidine; Mutation; Plasmids; Point Mutation; Promoter Regions, Genetic; Protein Structure, Tertiary; RNA; Trans-Activators; Transcription, Genetic | 2002 |
Genetic analysis of the His-to-Asp phosphorelay implicated in mitotic cell cycle control: involvement of histidine-kinase genes of Schizosaccharomyces pombe.
Topics: Amino Acid Sequence; Aspartic Acid; Cell Cycle Proteins; Histidine; Histidine Kinase; Mitosis; Molecular Sequence Data; Mutagenesis; Phosphorylation; Protein Kinases; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sequence Homology, Amino Acid; Signal Transduction | 2001 |
Two glutamate residues, Glu 208 alpha and Glu 197 beta, are crucial for phosphorylation and dephosphorylation of the active-site histidine residue in succinyl-CoA synthetase.
Topics: Adenosine; Alanine; Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Histidine; Hydrogen Bonding; Kinetics; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Succinate-CoA Ligases; Time Factors | 2002 |
Conserved residues in domain Ia are required for the reaction of Escherichia coli DNA ligase with NAD+.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; DNA Ligases; Dose-Response Relationship, Drug; Escherichia coli; Gene Deletion; Histidine; Kinetics; Ligands; Models, Biological; Molecular Sequence Data; Mutation; NAD; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Structure-Activity Relationship; Time Factors; Tyrosine | 2002 |
Modification of histidine (B10) is the causative agent for a superactive form of insulin.
Topics: Amino Acid Substitution; Amino Acids; Aspartic Acid; Bicarbonates; Histidine; Insulin; Sepharose; Structure-Activity Relationship | 2002 |
Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway.
Topics: Aspartic Acid; Bacterial Proteins; Binding Sites; Catalysis; Crystallography, X-Ray; Escherichia coli; Escherichia coli Proteins; Histidine; Manganese; Mevalonic Acid; Models, Chemical; Models, Molecular; Oxygen; Phosphates; Phosphorus-Oxygen Lyases; Protein Binding; Protein Structure, Quaternary; Substrate Specificity | 2002 |
S2' substrate specificity and the role of His110 and His111 in the exopeptidase activity of human cathepsin B.
Topics: Amidohydrolases; Aspartic Acid; Binding Sites; Cathepsin B; Exopeptidases; Glutamic Acid; Histidine; Humans; Ions; Kinetics; Lysosomes; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity; Tolbutamide | 2002 |
Genetic analysis of the RcsC sensor kinase from Escherichia coli K-12.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Conserved Sequence; Escherichia coli; Escherichia coli Proteins; Gene Expression; Genetic Complementation Test; Heat-Shock Proteins; Histidine; HSP40 Heat-Shock Proteins; Lac Operon; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Protein Kinases; Sequence Homology, Amino Acid | 2002 |
Surface aspartate residues are essential for the stability of colicin A P-domain: a mechanism for the formation of an acidic molten-globule.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Colicins; Histidine; Hydrogen-Ion Concentration; Ion Channels; Molecular Sequence Data; Mutagenesis, Insertional; Mutagenesis, Site-Directed; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Static Electricity; Surface Properties | 2002 |
An Arabidopsis histidine-containing phosphotransfer (HPt) factor implicated in phosphorelay signal transduction: overexpression of AHP2 in plants results in hypersensitiveness to cytokinin.
Topics: Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Cytokinins; Dose-Response Relationship, Drug; Ethylenes; Gene Expression Regulation, Plant; Histidine; Hypocotyl; Phosphorylation; Phosphotransferases; Plant Growth Regulators; Plant Proteins; Plants, Genetically Modified; Signal Transduction; Zeatin | 2002 |
Disparate binding of chaperone proteins by HLA-A subtypes.
Topics: Antiporters; Aspartic Acid; Blotting, Western; Cell Line; Flow Cytometry; Glutamine; Histidine; HLA-A Antigens; Humans; Immunoglobulins; Membrane Transport Proteins; Models, Molecular; Molecular Chaperones; Protein Binding; Protein Conformation; Structure-Activity Relationship; Substrate Specificity; Transfection | 2002 |
Naturally occurring mutation, Asp70his, in human butyrylcholinesterase.
Topics: Amino Acid Substitution; Apnea; Asian People; Aspartic Acid; Black People; Butyrylcholinesterase; Histidine; Humans; Kinetics; Point Mutation; Protein Binding; Succinylcholine; White People | 2002 |
Regulation of yeast actin behavior by interaction of charged residues across the interdomain cleft.
Topics: Actins; Adenosine Triphosphate; Aspartic Acid; Dose-Response Relationship, Drug; Fungal Proteins; Histidine; Methylhistidines; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Temperature; Time Factors | 2002 |
Crystal structure of beta 1,3-glucuronyltransferase I in complex with active donor substrate UDP-GlcUA.
Topics: Arginine; Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Glucuronosyltransferase; Histidine; Humans; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity; Temperature; Uridine Diphosphate Glucuronic Acid | 2002 |
Plasmid-encoded asp operon confers a proton motive metabolic cycle catalyzed by an aspartate-alanine exchange reaction.
Topics: Alanine; Amino Acid Sequence; Antiporters; Aspartic Acid; Carboxy-Lyases; Cell Membrane; Cloning, Molecular; Escherichia coli; Histidine; Lactobacillaceae; Molecular Sequence Data; Operon; Plasmids; Promoter Regions, Genetic; Proteolipids; Proton-Motive Force; Recombinant Proteins; RNA-Binding Proteins; Sequence Homology, Amino Acid | 2002 |
Polymorphisms of xenobiotic metabolizing genes in oropharyngeal carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Aspartic Acid; Carcinoma; Codon; Epoxide Hydrolases; Female; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Histidine; Homozygote; Humans; Isoenzymes; Male; Middle Aged; Oropharyngeal Neoplasms; Polymorphism, Genetic; Sex Factors; Statistics as Topic; Tyrosine | 2002 |
Prevalence of hemochromatosis-related symptoms among individuals with mutations in the HFE gene.
Topics: Adult; Aged; Aspartic Acid; Case-Control Studies; Cysteine; Double-Blind Method; Female; Ferritins; Genetic Predisposition to Disease; Genetic Testing; Genotype; Hemochromatosis; Hispanic or Latino; Histidine; Homozygote; Humans; Male; Middle Aged; Mutation; Prevalence; Surveys and Questionnaires; Transferrin; Tyrosine; United States; White People | 2002 |
The role of hydrophobic microenvironments in modulating pKa shifts in proteins.
Topics: Algorithms; Amine Oxidase (Copper-Containing); Amino Acids; Aspartic Acid; Binding Sites; Histidine; Hydrophobic and Hydrophilic Interactions; Micrococcal Nuclease; Models, Chemical; Models, Theoretical; Muramidase; Proteins; Solvents; Static Electricity; Titrimetry | 2002 |
Role of Asp193 in chromophore-protein interaction of pharaonis phoborhodopsin (sensory rhodopsin II).
Topics: Anions; Archaeal Proteins; Aspartic Acid; Bacteriorhodopsins; Carotenoids; Chlorine; Halorhodopsins; Histidine; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Photochemistry; Protein Binding; Protein Conformation; Schiff Bases; Sensory Rhodopsins; Spectrophotometry | 2002 |
Structure of arterivirus nsp4. The smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole.
Topics: Amino Acid Sequence; Anions; Arterivirus; Aspartic Acid; Binding Sites; Catalytic Domain; Chymotrypsin; Crystallography, X-Ray; Histidine; Models, Genetic; Models, Molecular; Molecular Sequence Data; Open Reading Frames; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases | 2002 |
Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I.
Topics: Alcaligenes; Amino Acid Substitution; Animals; Aspartic Acid; Catalytic Domain; Cattle; Chymotrypsin; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Osmolar Concentration; Serine Endopeptidases; Solvents; Species Specificity; Static Electricity; Trypsin; Tryptophan | 2002 |
Binding of D- and L-captopril inhibitors to metallo-beta-lactamase studied by polarizable molecular mechanics and quantum mechanics.
Topics: Algorithms; Aspartic Acid; Bacteroides fragilis; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Captopril; Computational Biology; Cysteine; Enzyme Inhibitors; Histidine; Models, Molecular; Molecular Structure; Protein Conformation; Serine; Static Electricity; Stereoisomerism; Zinc | 2002 |
Crystal structure of microbial transglutaminase from Streptoverticillium mobaraense.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalysis; Cross-Linking Reagents; Crystallography, X-Ray; Cysteine; Escherichia coli; Histidine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Streptomyces; Structure-Activity Relationship; Transglutaminases | 2002 |
Conserved residues in the putative catalytic triad of human bile acid Coenzyme A:amino acid N-acyltransferase.
Topics: Acyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Aspartic Acid; Bile Acids and Salts; Catalysis; Catalytic Domain; Cholic Acids; Coenzyme A; Conserved Sequence; Cysteine; DNA, Complementary; Dose-Response Relationship, Drug; Ethylmaleimide; Histidine; Humans; Kinetics; Models, Chemical; Molecular Sequence Data; Mutation; Protein Binding; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Time Factors; Trypsin | 2002 |
HLA-B27 subtypes differentially associated with disease exhibit subtle structural alterations.
Topics: Aspartic Acid; Crystallography, X-Ray; Databases as Topic; Escherichia coli; Histidine; HLA-B27 Antigen; Humans; Lysine; Models, Molecular; Peptides; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary | 2002 |
Mechanism of sulfide-quinone reductase investigated using site-directed mutagenesis and sulfur analysis.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Benzoquinones; Chromatography, High Pressure Liquid; Electron Transport; Enzyme Activation; Gene Expression Regulation, Bacterial; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Quinone Reductases; Recombinant Fusion Proteins; Spectrometry, Fluorescence; Substrate Specificity; Sulfates; Sulfides; Sulfur; Valine | 2002 |
Directed evolution experiments reveal mutations at cycloartenol synthase residue His477 that dramatically alter catalysis.
Topics: Amino Acid Sequence; Aspartic Acid; Catalysis; Conserved Sequence; Directed Molecular Evolution; Glutamic Acid; Histidine; Intramolecular Transferases; Lanosterol; Molecular Structure; Mutation; Structure-Activity Relationship; Yeasts | 2002 |
Zinc binding and dimerization of Streptococcus pyogenes pyrogenic exotoxin C are not essential for T-cell stimulation.
Topics: Amino Acid Sequence; Antigens; Aspartic Acid; Bacterial Toxins; Binding Sites; Binding, Competitive; Cations; Chromatography, Gel; Chromatography, Liquid; Circular Dichroism; Cloning, Molecular; Dimerization; DNA, Complementary; Dose-Response Relationship, Drug; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Secondary; Receptors, Antigen, T-Cell; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Streptococcus pyogenes; Surface Plasmon Resonance; T-Lymphocytes; Thermodynamics; Ultraviolet Rays; Zinc | 2003 |
Linkage of multiequilibria in DNA recognition by the D53H Escherichia coli cAMP receptor protein.
Topics: Amino Acid Substitution; Aspartic Acid; Binding Sites; Cyclic AMP; Cyclic AMP Receptor Protein; Cyclic GMP; DNA-Binding Proteins; DNA, Bacterial; Escherichia coli Proteins; Galactose; Histidine; Kinetics; Lactose; Point Mutation; Protein Binding; Protein Conformation; Thermodynamics | 2002 |
Association between hemochromatosis (HFE) gene mutation carrier status and the risk of colon cancer.
Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies; Colonic Neoplasms; Cysteine; Feeding Behavior; Female; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; Humans; Iron Compounds; Male; Meat; Membrane Proteins; Middle Aged; Mutation; North Carolina; Risk Assessment; Risk Factors; Tyrosine | 2003 |
Changes in stability upon charge reversal and neutralization substitution in staphylococcal nuclease are dominated by favorable electrostatic effects.
Topics: Amino Acid Substitution; Aspartic Acid; Enzyme Stability; Glutamic Acid; Glutamine; Guanidine; Histidine; Hydrogen-Ion Concentration; Lysine; Micrococcal Nuclease; Models, Chemical; Normal Distribution; Poisson Distribution; Protein Denaturation; Protein Folding; Static Electricity; Surface Properties; Thermodynamics | 2003 |
Chlorophyllase as a serine hydrolase: identification of a putative catalytic triad.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Carboxylic Ester Hydrolases; Catalysis; Chenopodium album; Enzyme Inhibitors; Histidine; Hydrolysis; Isoflurophate; Lipase; Molecular Sequence Data; Morpholines; Mutagenesis, Site-Directed; Mutation; p-Chloromercuribenzoic Acid; Phenylmethylsulfonyl Fluoride; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases | 2003 |
Pyruvate carboxylase is an essential protein in the assembly of yeast peroxisomal oligomeric alcohol oxidase.
Topics: Aspartic Acid; Blotting, Western; Cytosol; Glutamic Acid; Histidine; Immunohistochemistry; Microscopy, Electron; Mutation; Peroxisomes; Pichia; Plasmids; Protein Binding; Pyruvate Carboxylase; Spectrometry, Fluorescence; Time Factors | 2003 |
His-to-Asp phosphorelay circuitry for regulation of sexual development in Schizosaccharomyces pombe.
Topics: Anaerobiosis; Aspartic Acid; Gene Deletion; Genes, Fungal; Histamine; Histidine; Histidine Kinase; Hydrogen Peroxide; Meiosis; Nitrogen; Oxidative Stress; Protein Kinases; RNA, Fungal; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Signal Transduction | 2002 |
In vivo and in vitro characterization of the ARR11 response regulator implicated in the His-to-Asp phosphorelay signal transduction in Arabidopsis thaliana.
Topics: 2,4-Dichlorophenoxyacetic Acid; Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Cotyledon; Culture Techniques; Cytokinins; DNA-Binding Proteins; Gene Expression Regulation, Plant; Histidine; Multigene Family; Phosphorylation; Phylogeny; Plant Roots; Plant Shoots; Plants, Genetically Modified; Signal Transduction; Transcription Factors | 2003 |
NMR determination of pKa values for Asp, Glu, His, and Lys mutants at each variable contiguous enzyme-inhibitor contact position of the turkey ovomucoid third domain.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Genetic Variation; Glutamic Acid; Glycine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Lysine; Models, Chemical; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Ovomucin; Protein Conformation; Protein Structure, Tertiary; Serine Proteinase Inhibitors; Thermodynamics; Threonine; Titrimetry; Turkeys | 2003 |
Modeling zinc in biomolecules with the self consistent charge-density functional tight binding (SCC-DFTB) method: applications to structural and energetic analysis.
Topics: Alcohol Dehydrogenase; Algorithms; Aminopeptidases; Aspartic Acid; Bacterial Proteins; Binding Sites; Carbonic Anhydrases; Cysteine; Glutamic Acid; Histidine; Liver; Models, Molecular; Molecular Conformation; Protein Binding; Protein Conformation; Water; Zinc | 2003 |
Histidine and aspartic acid residues important for immunoglobulin G endopeptidase activity of the group A Streptococcus opsonophagocytosis-inhibiting Mac protein.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Binding Sites; Cysteine Endopeptidases; Histidine; Humans; Immunoglobulin G; Molecular Sequence Data; Mutagenesis, Site-Directed; Opsonin Proteins; Phagocytosis; Streptococcus pyogenes; Structure-Activity Relationship | 2003 |
CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Circular Dichroism; Cysteine; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Histidine; Humans; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrophotometry, Atomic; Ultracentrifugation; Ultraviolet Rays; Zinc; Zinc Fingers | 2003 |
Investigation of the role of the histidine-aspartate pair in the human exonuclease III-like abasic endonuclease, Ape1.
Topics: Aspartic Acid; Binding Sites; Calcium; Carbon-Oxygen Lyases; Catalysis; DNA; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Exodeoxyribonucleases; Histidine; Humans; Hydrolysis; Kinetics; Magnesium; Magnetic Resonance Spectroscopy; Models, Molecular; Oxidation-Reduction; Palladium; Protein Binding; Recombinant Proteins; Structure-Activity Relationship | 2003 |
Population screening for hemochromatosis: a study in 5370 Spanish blood donors.
Topics: Adult; Aspartic Acid; Blood Donors; Cysteine; Female; Ferritins; Gene Frequency; Genetic Testing; Genotype; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; Homozygote; Humans; Male; Membrane Proteins; Middle Aged; Mutation; Sex Characteristics; Spain; Transferrin; Tyrosine | 2003 |
Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity.
Topics: Adult; Amino Acid Substitution; Animals; Arizona; Aspartic Acid; Base Sequence; Body Composition; Cohort Studies; Diabetes Mellitus; Diabetes Mellitus, Type 2; DNA Primers; Glucose Clamp Technique; Glycine; Histidine; Humans; Hyperinsulinism; Indians, North American; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Mice; Obesity; Phosphoproteins; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Regression Analysis | 2003 |
Asp274 and his346 are essential for heme binding and catalytic function of human indoleamine 2,3-dioxygenase.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Blotting, Western; Catalysis; Cell Division; Circular Dichroism; Cytokines; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Heme; Histidine; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kinetics; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Protein Conformation; Rats; Sequence Homology, Amino Acid; Tryptophan; Tryptophan Oxygenase; Ultraviolet Rays; Up-Regulation | 2003 |
A low-barrier hydrogen bond between histidine of secreted phospholipase A2 and a transition state analog inhibitor.
Topics: Animals; Aspartic Acid; Bee Venoms; Binding Sites; Cattle; Enzyme Inhibitors; Histidine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Phospholipases A; Phospholipases A2; Phospholipids; Protons | 2003 |
The human bile acid-CoA:amino acid N-acyltransferase functions in the conjugation of fatty acids to glycine.
Topics: Acyltransferases; Amino Acid Sequence; Animals; Aspartic Acid; Bile Acids and Salts; Catalysis; Cloning, Molecular; Cysteine; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fatty Acids; Fibroblasts; Gallbladder; Glycine; Green Fluorescent Proteins; Histidine; Humans; Intestines; Kinetics; Liver; Luminescent Proteins; Mass Spectrometry; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Recombinant Fusion Proteins; Recombinant Proteins; Taurine; Tissue Distribution | 2003 |
Glutamic acid residues as metal ligands in the active site of Escherichia coli alkaline phosphatase.
Topics: Alkaline Phosphatase; Amino Acid Substitution; Aspartic Acid; Binding Sites; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Ligands; Magnesium; Metals; Mutagenesis, Site-Directed; Phosphorylation; Structure-Activity Relationship; Zinc | 2003 |
Studies on type I collagen in skin fibroblasts cultured from twins with lethal osteogenesis imperfecta.
Topics: Aspartic Acid; Base Sequence; Cells, Cultured; Collagen Type I; Cyanogen Bromide; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Histidine; Humans; Infant; Osteogenesis Imperfecta; Peptide Fragments; Point Mutation; Procollagen; Proline; Skin; Trypsin; Twins | 2003 |
Surface histidine residue of archaeal histone affects DNA compaction and thermostability.
Topics: Amino Acid Substitution; Aspartic Acid; DNA, Archaeal; Gene Expression Regulation, Archaeal; Histidine; Histones; Hot Temperature; Mutagenesis, Site-Directed; Thermococcus | 2003 |
Molecular characterization of His-Asp phosphorelay signaling factors in maize leaves: implications of the signal divergence by cytokinin-inducible response regulators in the cytosol and the nuclei.
Topics: Aspartic Acid; Cell Nucleus; Cloning, Molecular; Cytokinins; Cytosol; DNA, Complementary; Gene Expression Regulation, Plant; Genetic Variation; Green Fluorescent Proteins; Histidine; Luminescent Proteins; Microscopy, Confocal; Molecular Sequence Data; Phosphorylation; Phylogeny; Plant Leaves; Plant Proteins; Protein Binding; Recombinant Fusion Proteins; RNA, Plant; Saccharomyces cerevisiae; Sequence Analysis, DNA; Signal Transduction; Two-Hybrid System Techniques; Zea mays | 2003 |
The NMR solution structure of BeF(3)(-)-activated Spo0F reveals the conformational switch in a phosphorelay system.
Topics: Aspartic Acid; Bacillus subtilis; Bacterial Proteins; Beryllium; Fluorides; Histidine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Phosphotransferases; Protein Conformation; Signal Transduction | 2003 |
Crystal structure of a mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Bacterial Proteins; Binding Sites; Carbon; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cyanobacteria; DNA Helicases; DnaB Helicases; Genetic Vectors; Histidine; Models, Chemical; Models, Genetic; Models, Molecular; Molecular Sequence Data; Oxygen; Peptides; Protein Conformation; Protein Splicing; Protein Structure, Tertiary; RNA Splicing; Sequence Homology, Amino Acid; Structure-Activity Relationship; Water | 2003 |
Mechanism of proton transfer inhibition by Cd(2+) binding to bacterial reaction centers: determination of the pK(A) of functionally important histidine residues.
Topics: Aspartic Acid; Binding Sites; Cadmium; Electron Transport; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Protein Binding; Protons; Quinones; Recombinant Proteins; Rhodobacter sphaeroides | 2003 |
Characterization of a potent human interleukin-11 agonist.
Topics: Animals; Aspartic Acid; Cell Division; Cell Line; Circular Dichroism; Histidine; Humans; Hydrophobic and Hydrophilic Interactions; Interleukin-11; Interleukin-11 Receptor alpha Subunit; Mice; Models, Molecular; Mutagenesis, Site-Directed; Receptors, Interleukin; Receptors, Interleukin-11; Spectrophotometry, Infrared | 2003 |
Synthesis and hydrolysis studies of a peptide containing the reactive triad of serine proteases with an associated linker to a dye on a solid phase support.
Topics: Amino Acid Sequence; Aspartic Acid; Coloring Agents; Combinatorial Chemistry Techniques; Esterases; Histidine; Hydrolysis; Microspheres; Molecular Sequence Data; Oligopeptides; Serine; Serine Endopeptidases | 2003 |
Computational study on mechanistic details of the aminoethanol rearrangement catalyzed by the vitamin B12-dependent ethanolamine ammonia lyase: His and Asp/Glu acting simultaneously as catalytic auxiliaries.
Topics: Aspartic Acid; Binding Sites; Catalysis; Computational Biology; Ethanolamine Ammonia-Lyase; Ethanolamines; Glutamic Acid; Histidine; Indicators and Reagents; Molecular Conformation; Thermodynamics; Vitamin B 12 | 2003 |
Does aspartate 170 of the D1 polypeptide ligate the manganese cluster in photosystem II? An EPR and ESEEM Study.
Topics: Amino Acid Substitution; Aspartic Acid; Cyanobacteria; Electron Spin Resonance Spectroscopy; Fourier Analysis; Histidine; Light; Manganese; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Protein Subunits; Recombinant Proteins | 2003 |
Amino acid composition and electrophoretic properties of hypertensin I.
Topics: Amino Acids; Angiotensin Amide; Angiotensins; Arginine; Aspartic Acid; Glycine; Histidine; Isoleucine; Leucine; Phenylalanine; Proline; Serine; Tyrosine; Valine | 1955 |
The nutrition of animal tissues cultivated in vitro. IV. Amino acid requirements of chick embryonic heart fibroblasts.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Fibroblasts; Glycine; Histidine; Hydroxyproline; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
Gamma irradiation of polypeptides: transformation of amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Glutamates; Glutamic Acid; Glycine; Histidine; Methionine; Peptides; Phenylalanine; Proline; Radiation Effects; Tyrosine | 1963 |
[Inhibition and reactivation of the hydrolases of digestion].
Topics: Alkaline Phosphatase; Amylases; Arginine; Aspartic Acid; Bilirubin; Chymotrypsin; Digestion; Histidine; Humans; Hydrolases; Intestine, Small; Intestines; Oleic Acid; Oleic Acids; Palmitic Acid; Stearic Acids; Trypsin | 1962 |
Nematode biochemistry. II. Biosynthesis of amino acids.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Nematoda; Serine; Threonine; Tyrosine; Valine | 1962 |
Effects of glucogenic amino-acids on frog's heart. II.
Topics: Amino Acids; Aspartic Acid; Glutamates; Heart; Histidine | 1963 |
[THE DEAMINATION OF SEVERAL AMINO ACIDS IN THE LIVER OF EMBRYOS DURING THE TRANSITION FROM UREOTELISM TO URICOTELISM].
Topics: Amino Acids; Aspartic Acid; Chick Embryo; Cysteine; Deamination; Glutamates; Histidine; Hydroxylamines; Liver; Ornithine; Pharmacology; Proteins; Research; Urea; Uric Acid; Valine | 1963 |
STUDIES ON COLLETOTRICHUM CAPSICI III. THE EFFECT OF INITIAL PH ON THE GROWTH AND AMINO ACID COMPOSITION.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Chromatography; Colletotrichum; Cysteine; Fungi; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Phenylalanine; Research; Serine; Tyrosine | 1963 |
SPECIFICITY OF PEPSIN AND ITS DEPENDENCE ON A POSSIBLE 'HYDROPHOBICBINDING SITE'.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pepsin A; Peptides; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
THIN-LAYER CHROMATOGRAPHIC SEPARATION AND QUANTITATIVE DETERMINATION OF SEVERAL FREE AMINO-ACIDS OF AVIAN LIVER.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography; Histidine; Leucine; Liver; Lysine; Poultry; Research; Valine | 1963 |
EFFECT OF RESERPINE ON AMINO ACIDS IN BRAIN.
Topics: 5-Hydroxytryptophan; Amino Acids; Aminobutyrates; Aspartic Acid; Brain; Glutamates; Histidine; Hydroxyproline; Nitrogen; Pharmacology; Phenylalanine; Proline; Proteins; Rats; Research; Reserpine; Tryptophan; Tyrosine | 1963 |
THE INHIBITION OF CEREBRAL DIGLYCINASE BY ALPHA-AMINO-, ALPHA-KETO- AND ALPHA-HYDROXY ACIDS.
Topics: Alanine; Aminobutyrates; Animals; Arginine; Aspartic Acid; Brain; Cobalt; Enzyme Inhibitors; Histidine; Hydroxy Acids; Keto Acids; Leucine; Methionine; Mice; Peptide Hydrolases; Peptides; Pharmacology; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Valine | 1963 |
BIOCHEMISTRY OF LUNGS IN RELATION TO SILICOSIS. II. THE EFFECT OF QUARTZ DUST ON THE PROTEIN AMINO ACIDS OF GUINEA PIG LUNG TISSUE.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Collagen; Cystine; Dust; Glutamates; Glycine; Guinea Pigs; Histidine; Hydroxyproline; Isoleucine; Leucine; Lung; Lysine; Methionine; Phenylalanine; Proline; Quartz; Research; Serine; Silicon Dioxide; Silicosis; Threonine; Toxicology; Tyrosine; Valine | 1964 |
[INFLUENCE OF HISTIDINE AND ITS METABOLITES ON THE BIOSYNTHESIS OF PURINES IN ESCHERICHIA COLI B. VI. INCORPORATION OF THE IMIDE NITROGEN OF FORMIMINOGLUTAMIC AND -ASPARTIC ACIDS INTO 5-AMINO-4-IMIDAZOLECARBOXAMIDE RIBOTIDE].
Topics: Aminoimidazole Carboxamide; Aspartic Acid; Escherichia coli; Glutamates; Histidine; Imidazoles; Imides; Metabolism; Nitrogen; Pharmacology; Purines; Research; Ribonucleotides | 1963 |
NITROGEN BALANCES FOR YOUNG ADULT MALES FED TWO SOURCES OF NONESSENTIAL NITROGEN AT TWO LEVELS OF TOTAL NITROGEN INTAKE.
Topics: Alanine; Ammonium Compounds; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Male; Nitrogen; Nitrogen Fixation; Proline; Proteins; Quaternary Ammonium Compounds; Serine | 1964 |
NUTRITION AND BIOCHEMISTRY OF SURVIVAL DURING NEWCASTLE DISEASE VIRUS INFECTION. II. RELATION OF CLINICAL SYMPTOMS AND STARVATION TO NUCLEIC AND FREE AMINO ACIDS OF AVIAN LIVER.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Birds; Body Temperature; Body Weight; Chromatography; DNA; Histidine; Histocytochemistry; Leucine; Liver; Lysine; Newcastle Disease; Newcastle disease virus; Proteins; Research; RNA; Starvation; Valine | 1964 |
NUTRITION AND BIOCHEMISTRY OF SURVIVAL DURING NEWCASTLE DISEASE VIRUS INFECTION. III. RELATION OF DIETARY PROTEIN TO NUCLEIC AND FREE AMINO ACIDS OF AVIAN LIVER.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Birds; Chromatography; Dietary Proteins; DNA; Hemagglutination Inhibition Tests; Histidine; Histocytochemistry; Leucine; Liver; Lysine; Newcastle Disease; Newcastle disease virus; Protein Deficiency; Proteins; Research; RNA; Valine | 1964 |
THE ROLE OF DISPENSABLE AMINO ACIDS IN THE NUTRITION OF THE RAT.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bicarbonates; Caseins; Cystine; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Lysine; Methionine; Phenylalanine; Proline; Proteins; Rats; Research; Serine; Tyrosine | 1964 |
THE CONTENT OF AMINO ACIDS IN THE PROTEINS OF THE DEVELOPING NERVOUS SYSTEM OF THE GUINEA PIG. III. SPINAL CORD.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cystine; Fetus; Glutamates; Glycine; Guinea Pigs; Histidine; Leucine; Lysine; Nerve Tissue Proteins; Nervous System; Phenylalanine; Research; Serine; Spinal Cord; Threonine; Tyrosine; Valine | 1964 |
DYNAMIC PHENOMENA IN MICROSPHERES FROM THERMAL PROTEINOID.
Topics: Alanine; Arginine; Aspartic Acid; Colloids; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Microspheres; Peptides; Phenylalanine; Photomicrography; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
THE INHIBITION OF MITOCHONDRIAL ADENOSINE TRIPHOSPHATASE. 2. THE EFFECTS OF AMINO ACIDS AND SUGARS.
Topics: Adenosine Triphosphatases; Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Enzyme Inhibitors; Fructose; Glutamates; Glycine; Histidine; Hydroxyproline; Isoleucine; Lactose; Liver; Lysine; Methionine; Mitochondria; Oligosaccharides; Pharmacology; Proline; Rats; Research; Serine; Threonine; Valine | 1964 |
TRANSAMINATION IN PERFUSED RAT LIVER.
Topics: Alanine; Amino Acids; Aspartic Acid; Carbon Dioxide; Glutamates; Histidine; Isoleucine; Leucine; Liver; Metabolism; Methionine; Oxalates; Oxygen; Perfusion; Physiology; Potassium; Proteins; Pyruvates; Rats; Research; Valine; Water | 1964 |
CHROMATOGRAPHIC SEPARATION OF PYRIDOXYL DERIVATIVES OF AMINO ACIDS.
Topics: Alanine; Amines; Amino Acids; Arginine; Aspartic Acid; Chromatography; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Phenylalanine; Pyridines; Pyridoxine; Research; Serine; Threonine; Tyrosine; Valine | 1964 |
BIOSYNTHESIS OF BACITRACIN. I. FORMATION OF BACITRACIN BY A SUBCELLULAR FRACTION OF BACILLUS LICHENIFORMIS.
Topics: Asparagine; Aspartic Acid; Bacillus; Bacitracin; Carbon Isotopes; Chromatography; Cysteine; Cystine; Glutamates; Glutathione; Histidine; Isoleucine; Lysine; Metabolism; Micrococcus; Ornithine; Phenylalanine; Research; Subcellular Fractions; Sulfhydryl Compounds; Sulfur Isotopes | 1964 |
[FREE AMINO ACIDS IN THE BLOOD AND URINE OF PATIENTS WITH SOME FORMS OF DERMATOSIS].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Blood; Cystine; Dermatitis; Eczema; Erythema Multiforme; Glutamates; Glycine; Histidine; Lupus Erythematosus, Systemic; Lysine; Proteins; Psoriasis; Renal Aminoacidurias; Serine; Skin Diseases; Taurine; Threonine; Toxicology; Tryptophan; Urticaria | 1964 |
[ON THE HORMONAL REGULATION OF PROTEIN METABOLISM. THE EFFECT ON INSULIN AND GLUCAGON].
Topics: Alanine; Arginine; Aspartic Acid; Blood Glucose; Carbohydrate Metabolism; Glucagon; Glutamates; Glycine; Histidine; Insulin; Leucine; Lysine; Pharmacology; Phenylalanine; Proteins; Threonine; Tyrosine; Valine | 1964 |
NUTRITIONAL FACTORS RELATING TO GROWTH AND OXYTETRACYCLINE FORMATION BY STREPTOMYCES RIMOSUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Cysteine; Cystine; Glutamine; Glycine; Histidine; Isoleucine; Lysine; Metabolism; Methionine; Oxytetracycline; Research; Serine; Streptomyces; Streptomyces rimosus | 1964 |
NUTRITION AND BIOCHEMISTRY OF SURVIVAL DURING NEWCASTLE DISEASE VIRUS INFECTION: DIURNAL CHANGES IN PROTEIN, NUCLEIC AND FREE AMINO ACIDS OF AVIAN LIVER.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Clocks; Birds; DNA; Histidine; Leucine; Liver; Lysine; Newcastle Disease; Newcastle disease virus; Periodicity; Poultry; Proteins; Research; RNA; Survival; Valine | 1964 |
SOME IN VITRO STUDIES OF POLONIUM-210 BINDING BY BLOOD CONSTITUENTS.
Topics: Amino Acids; Aspartic Acid; Bicarbonates; Blood; Citrates; Cysteine; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Malates; Metabolism; Phosphates; Polonium; Research; Serine; Tryptophan | 1964 |
COMPARATIVE RADIOLABILITY OF AMINO ACIDS OF PROTEINS AND FREE AMINO ACIDS.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Catalase; Chromatography; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Ovalbumin; Phenylalanine; Proteins; Radiation Effects; Research; Serine; Valine | 1964 |
THE INCORPORATION OF LABELED AMINO ACIDS INTO LENS PROTEIN.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cattle; Chromatography; Crystallins; Eye Proteins; Histidine; Lens, Crystalline; Phenylalanine; Proteins; Rabbits; Research; Tyrosine | 1964 |
THE MACROMOLECULAR ORGANIZATION OF DENTINE MATRIX COLLAGEN. II. PERIODATE DEGRADATION AND CARBOHYDRATE CROSS-LINKING.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Carbohydrates; Cattle; Chemistry Techniques, Analytical; Collagen; Dentin; Electrophoresis; Glutamates; Hexoses; Histidine; Humans; Hydroxyproline; Molecular Weight; Nitrogen; Oxidation-Reduction; Peptides; Periodic Acid; Phosphates; Research; Serine; Skin; Solubility; Tyrosine | 1964 |
STUDIES ON THE AMINO ACIDS IN YEAST RNA IN BOUND FORM. 3. DINITROPHENYLATION STUDIES ON THE PURIFIED YEAST RNA.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemistry Techniques, Analytical; Chromatography; Dinitrophenols; Electrophoresis; Histidine; Peptides; Research; RNA; RNA, Bacterial; Saccharomyces; Serine; Spectrum Analysis; Ultracentrifugation | 1964 |
HEMOGLOBIN G(BALTIMORE): A NEW ABNORMAL HEMOGLOBIN, AND AN ADDITIONAL INDIVIDUAL WITH FOUR HEMOGLOBINS.
Topics: Aspartic Acid; Baltimore; Black People; Blood Protein Electrophoresis; Genetics, Medical; Hemoglobin C; Hemoglobins; Hemoglobins, Abnormal; Histidine; Humans; Maryland; Mutation; Peptides; Proteins | 1965 |
CHLORIDE- AND HYDROGEN-ION BINDING TO RIBONUCLEASE.
Topics: Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Chlorides; Glutamates; Histidine; Hydrogen; Lysine; Research; Ribonucleases; Valine | 1964 |
[ON HEMOGLOBIN. XX. COMPARATIVE STUDY ON THE PRIMARY STRUCTURE OF HEMOGLOBIN IN MACACCUS RHESUS MONKEYS AND HUMAN HEMOGLOBIN WITH THE USE OF COMBINED ENZYMATIC HYDROLYSIS].
Topics: Amino Acids; Animals; Aspartic Acid; Haplorhini; Hemoglobins; Histidine; Histocytochemistry; Humans; Hydrolysis; Macaca mulatta; Research; Tyrosine | 1965 |
PROTEIN METABOLISM IN LIVERS OF CHICKS FED DEFICIENT-TO QUANTITIES OF PROTEIN AND LYSINE AND INFECTED WITH TUBERCULOSIS.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Body Weight; Chickens; Dietary Proteins; DNA; Histidine; Leucine; Liver; Lysine; Organ Size; Poultry; Proteins; Research; RNA; Tuberculosis; Tuberculosis, Avian; Valine | 1965 |
EFFECT OF AMINO ACIDS ON GROWTH OF SPHAEROTILUS DISCOPHORUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Bacteriological Techniques; Caseins; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Proline; Research; Serine; Sphaerotilus; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
STUDIES ON HUMAN ANTIBODIES. 3. AMINO ACID COMPOSITION OF FOUR ANTIBODIES FROM ONE INDIVIDUAL.
Topics: Alanine; Amino Acids; Antibodies; Arginine; Aspartic Acid; Chemistry Techniques, Analytical; gamma-Globulins; Glutamates; Glycine; Histidine; Immunochemistry; Immunoglobulins; Isoleucine; Leucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1965 |
DETERMINATION OF BACTERIAL DECARBOXYLASES OF SOME AMINO ACIDS BY MEANS OF HIGH VOLTAGE PAPER ELECTROPHORESIS.
Topics: Achromobacter; Amino Acids; Arginine; Aspartic Acid; Bacteria; Carboxy-Lyases; Electrophoresis; Electrophoresis, Paper; Enterobacteriaceae; Escherichia coli; Glutamates; Histidine; Lysine; Ornithine; Phenylalanine; Proteus; Pseudomonas; Serine; Tryptophan; Tyrosine | 1965 |
RECENT DEVELOPMENTS IN THE UNDERSTANDING OF AMINO-ACID AND PROTEIN METABOLISM BY SCHISTOSOMA MANSONI IN VITRO.
Topics: Alanine; Amino Acids; Animals; Arginase; Arginine; Aspartic Acid; Carbon Isotopes; Glucose; Hemoglobins; Histidine; In Vitro Techniques; Ornithine; Peptides; Proline; Proteins; Radiometry; Research; Schistosoma; Schistosoma mansoni; Tryptophan; Urea | 1965 |
The crystal structure of Escherichia coli heat shock protein YedU reveals three potential catalytic active sites.
Topics: Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cysteine; Dimerization; Electronic Data Processing; Escherichia coli Proteins; Glutamic Acid; Heat-Shock Proteins; Histidine; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Chaperones; Molecular Sequence Data; Protein Structure, Quaternary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Structural Homology, Protein; Zinc | 2003 |
Role of aspartate-133 and histidine-458 in the mechanism of tryptophan indole-lyase from Proteus vulgaris.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Aspartic Acid; Binding Sites; Binding, Competitive; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Proteus vulgaris; Sequence Alignment; Sequence Homology, Amino Acid; Spectrophotometry; Tryptophanase | 2003 |
Mutagenesis of putative catalytic and regulatory residues of Streptomyces chromofuscus phospholipase D differentially modifies phosphatase and phosphodiesterase activities.
Topics: Acid Phosphatase; Amino Acid Sequence; Aspartic Acid; Binding Sites; Calcium; Calorimetry; Catalytic Domain; Circular Dichroism; Glutamine; Glycoproteins; Histidine; Hydrolysis; Ions; Iron; Kinetics; Magnesium; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Sequence Data; Mutation; Phospholipase D; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry; Streptomyces; Time Factors; Ultraviolet Rays | 2003 |
Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Catalysis; Enzyme Inhibitors; Histidine; Humans; Hydrolysis; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Nitrophenols; Organophosphorus Compounds; Peptides; Phenylalanine; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 3; Protein Tyrosine Phosphatases; Sequence Alignment; Vanadates | 2004 |
Lecithin retinol acyltransferase is a founder member of a novel family of enzymes.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalytic Domain; Conserved Sequence; Cysteine; Cysteine Endopeptidases; Glutamine; Histidine; Humans; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Phosphatidylcholine-Sterol O-Acyltransferase | 2003 |
Defining the bacteriophage T4 DNA packaging machine: evidence for a C-terminal DNA cleavage domain in the large terminase/packaging protein gp17.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Aspartic Acid; Bacteriophage T4; Binding Sites; Cysteine; DNA; Endodeoxyribonucleases; Histidine; Molecular Sequence Data; Mutation; Sequence Alignment; Viral Proteins | 2003 |
Role of His-16 in turnover of T4 pyrimidine dimer glycosylase.
Topics: Alanine; Aspartic Acid; Cell Survival; Cysteine; Dimerization; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Lysine; Models, Biological; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Phenotype; Plasmids; Serine; Time Factors; Ultraviolet Rays | 2004 |
Histidine ligand protonation and redox potential in the rieske dioxygenases: role of a conserved aspartate in anthranilate 1,2-dioxygenase.
Topics: Acinetobacter; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Dithionite; Electron Spin Resonance Spectroscopy; Histidine; Hydrogen-Ion Concentration; Iron-Sulfur Proteins; Ligands; Mixed Function Oxygenases; Models, Molecular; NADP; Oxidation-Reduction; Protons; Recombinant Proteins; Spectrophotometry, Ultraviolet | 2003 |
Functionally important amino acids in Saccharomyces cerevisiae aspartate kinase.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Aspartate Kinase; Aspartic Acid; Cloning, Molecular; Escherichia coli; Histidine; Isoleucine; Kinetics; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Threonine | 2003 |
His-Asp signal transduction via a monomeric histidine phosphotransfer protein.
Topics: Aspartic Acid; Bacillus subtilis; Binding Sites; Crystallography, X-Ray; DNA-Binding Proteins; Escherichia coli; Histidine; Intracellular Signaling Peptides and Proteins; Models, Molecular; Protein Kinases; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2003 |
Functional analysis of amino acids of the Na+/H+ exchanger that are important for proton translocation.
Topics: Amino Acids; Aspartic Acid; Biological Transport; Cations; Cell Division; Cell Membrane; Cloning, Molecular; Cytosol; DNA; Histidine; Ions; Models, Biological; Mutagenesis, Site-Directed; Mutation; Plasmids; Protons; Schizosaccharomyces; Sodium; Sodium Chloride; Sodium-Hydrogen Exchangers; Superoxide Dismutase; Time Factors | 2003 |
Mechanism of proton gating of a urea channel.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Bacterial Proteins; Biological Transport; Cell Membrane; Glutamic Acid; Helicobacter hepaticus; Helicobacter pylori; Histidine; Hydrogen-Ion Concentration; Membrane Transport Proteins; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Structure, Tertiary; Protons; RNA; Sequence Homology, Amino Acid; Streptococcus; Urea; Urease; Xenopus; Xenopus laevis | 2004 |
Identification and characterization of the conserved nucleoside-binding sites in the Epstein-Barr virus thymidine kinase.
Topics: Amino Acid Sequence; Aspartic Acid; Binding, Competitive; Blotting, Western; Conserved Sequence; Herpesvirus 4, Human; Histidine; Humans; Inhibitory Concentration 50; Kinetics; Metals; Models, Molecular; Molecular Sequence Data; Mutation; Nucleosides; Phenylalanine; Protein Conformation; Substrate Specificity; Thymidine; Thymidine Kinase; Valine | 2004 |
JAMM: a metalloprotease-like zinc site in the proteasome and signalosome.
Topics: Amino Acid Motifs; Animals; Archaea; Archaeoglobus fulgidus; Aspartic Acid; Binding Sites; DNA-Binding Proteins; Glutamic Acid; Histidine; Humans; Hydrogen Bonding; Metalloproteases; Molecular Sequence Data; Mutagenesis; NEDD8 Protein; Open Reading Frames; Proteasome Endopeptidase Complex; Protein Conformation; Protein Folding; Signal Transduction; Thermolysin; Transcription Factors; Ubiquitins; Zinc | 2004 |
The role of the conserved histidine-aspartate pair in the 'base-off' binding of cobalamins.
Topics: Aspartic Acid; Carbon; Clostridium; Cobalt; Histidine; Intramolecular Transferases; Molecular Structure; Mutation; Protein Binding; Spectrum Analysis; Vitamin B 12 | 2004 |
Crystal structure of haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26 at 0.95 A resolution: dynamics of catalytic residues.
Topics: Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Chlorides; Computer Simulation; Crystallization; Crystallography, X-Ray; Histidine; Hydrolases; Models, Molecular; Protein Conformation; Quantum Theory; Sphingomonas; Thermodynamics | 2004 |
Comparative studies on the type-B response regulators revealing their distinctive properties in the His-to-Asp phosphorelay signal transduction of Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Aspartic Acid; DNA-Binding Proteins; Gene Expression Regulation, Plant; Histidine; Histidine Kinase; Phosphorylation; Plants, Genetically Modified; Protein Kinases; Protein Structure, Tertiary; Signal Transduction; Transcription Factors | 2004 |
Pseudosubstrate peptides inhibit Akt and induce cell growth inhibition.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Aspartic Acid; Binding, Competitive; Cell Line, Tumor; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Growth Inhibitors; HeLa Cells; Histidine; Humans; Molecular Sequence Data; Peptides; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Substrate Specificity | 2004 |
Identification of two novel mutations in the Cu/Zn superoxide dismutase gene with familial amyotrophic lateral sclerosis: mass spectrometric and genomic analyses.
Topics: Age of Onset; Amyotrophic Lateral Sclerosis; Aspartic Acid; Chromatography, Liquid; DNA Mutational Analysis; Erythrocytes; Exons; Family Health; Female; Glutamic Acid; Glycine; Histidine; Humans; Male; Molecular Biology; Molecular Sequence Data; Mutation; Precipitin Tests; Spectrometry, Mass, Electrospray Ionization; Superoxide Dismutase | 2004 |
The influence of solvation on short strong hydrogen bonds: a density functional theory study of the Asp-His interaction in subtilisins.
Topics: Aspartic Acid; Histidine; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Subtilisins | 2004 |
Comparative studies of the AHP histidine-containing phosphotransmitters implicated in His-to-Asp phosphorelay in Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Blotting, Northern; Escherichia coli; Histidine; Phosphorylation; Phosphotransferases; Signal Transduction; Yeasts | 2004 |
Binding ability of a HHP-tagged protein towards Ni2+ studied by paramagnetic NMR relaxation: the possibility of obtaining long-range structure information.
Topics: Aspartic Acid; Dimerization; Escherichia coli; Glutamic Acid; Histidine; Models, Theoretical; Nickel; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Tertiary; Protons; Recombinant Fusion Proteins; Thioredoxins | 2004 |
Differential roles of Arg97, Asp293, and Arg108 in enzyme stability and substrate specificity of CYP2C9.
Topics: Amino Acid Substitution; Arginine; Aryl Hydrocarbon Hydroxylases; Aspartic Acid; Binding Sites; Cytochrome P-450 CYP2C9; Diclofenac; Enzyme Stability; Gene Expression; Histidine; Humans; Kinetics; Models, Molecular; Mutagenesis; Pyrenes; Substrate Specificity; Warfarin | 2004 |
Structure of a feruloyl esterase from Aspergillus niger.
Topics: Amino Acid Sequence; Aspartic Acid; Aspergillus niger; Bacterial Proteins; Binding Sites; Carboxylic Ester Hydrolases; Catalytic Domain; Coumaric Acids; Crystallography, X-Ray; Fungal Proteins; Histidine; Lipase; Models, Molecular; Molecular Sequence Data; Protein Conformation; Sequence Homology, Amino Acid; Serine; Structural Homology, Protein | 2004 |
The low barrier hydrogen bond (LBHB) proposal revisited: the case of the Asp... His pair in serine proteases.
Topics: Aspartic Acid; Binding Sites; Catalysis; Chymotrypsin; Histidine; Hydrogen Bonding; Models, Chemical; Models, Molecular; Serine Endopeptidases | 2004 |
Mechanism for the hydrolysis of organophosphates by the bacterial phosphotriesterase.
Topics: Aryldialkylphosphatase; Aspartic Acid; Bacterial Proteins; Cadmium; Deuterium Exchange Measurement; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Organophosphorus Compounds; Pseudomonas; Solvents; Substrate Specificity; Tyrosine; Zinc | 2004 |
Comparison between catalase-peroxidase and cytochrome c peroxidase. The role of the hydrogen-bond networks for protein stability and catalysis.
Topics: Archaeal Proteins; Asparagine; Aspartic Acid; Bacterial Proteins; Catalysis; Cyanobacteria; Cytochrome-c Peroxidase; Enzyme Stability; Ferric Compounds; Ferrous Compounds; Haloarcula marismortui; Histidine; Hydrogen Bonding; Mutagenesis, Site-Directed; Peroxidases; Proline; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Tryptophan | 2004 |
Long-range nature of the interactions between titratable groups in Bacillus agaradhaerens family 11 xylanase: pH titration of B. agaradhaerens xylanase.
Topics: Aspartic Acid; Bacillus; Bacterial Proteins; Carboxylic Acids; Endo-1,4-beta Xylanases; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Imidazoles; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protons; Recombinant Proteins; Static Electricity; Titrimetry | 2004 |
Frequency of the C282Y and H63D mutations of the hemochromatosis gene (HFE) in 2501 ethnic Danes.
Topics: Aspartic Acid; Confidence Intervals; Cysteine; Denmark; Female; Gene Frequency; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Male; Membrane Proteins; Mutation; Tyrosine | 2004 |
Genome-wide comparison of the His-to-Asp phosphorelay signaling components of three symbiotic genera of Rhizobia.
Topics: Arabidopsis; Aspartic Acid; Genome, Bacterial; Histidine; Histidine Kinase; Phosphorylation; Protein Kinases; Rhizobium; Signal Transduction; Symbiosis | 2004 |
HFE gene and hemochromatosis.
Topics: Aspartic Acid; Cysteine; Gene Frequency; Hemochromatosis; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; Homozygote; Humans; Membrane Proteins; Mutation; Mutation, Missense; Tyrosine | 2004 |
The catalytic role of aspartate in a short strong hydrogen bond of the Asp274-His32 catalytic dyad in phosphatidylinositol-specific phospholipase C can be substituted by a chloride ion.
Topics: Anions; Aspartic Acid; Bacillus thuringiensis; Binding Sites; Catalysis; Chlorides; Dose-Response Relationship, Drug; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Ions; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Monte Carlo Method; Mutation; Normal Distribution; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Structure-Activity Relationship | 2004 |
Potyviral NIa proteinase, a proteinase with novel deoxyribonuclease activity.
Topics: Aspartic Acid; Cell Nucleus; Cysteine; Cytoplasm; Deoxyribonucleases; DNA; DNA Mutational Analysis; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Escherichia coli; Glutathione Transferase; Green Fluorescent Proteins; Histidine; Hydrogen-Ion Concentration; Ions; Kinetics; Luminescent Proteins; Magnesium; Models, Molecular; Mutation; Plasmids; Point Mutation; Potyvirus; Recombinant Fusion Proteins; Recombinant Proteins; Sodium Chloride; Solanum tuberosum; Time Factors; Viral Proteins | 2004 |
Modulation of ligand selectivity associated with activation of the transmembrane region of the human follitropin receptor.
Topics: Animals; Aspartic Acid; Cell Membrane; Chlorocebus aethiops; COS Cells; Cyclic AMP; Gene Expression Regulation; Histidine; Humans; Ligands; Models, Molecular; Mutation; Protein Structure, Tertiary; Receptors, FSH; Structure-Activity Relationship; Substrate Specificity; Threonine | 2004 |
The HD domain of the Escherichia coli tRNA nucleotidyltransferase has 2',3'-cyclic phosphodiesterase, 2'-nucleotidase, and phosphatase activities.
Topics: Adenosine Monophosphate; Amino Acid Sequence; Aspartic Acid; Calcium; Chromatography, Thin Layer; Cloning, Molecular; Conserved Sequence; Cyclic AMP; Cyclic CMP; Cyclic GMP; Dose-Response Relationship, Drug; Escherichia coli; Histidine; Hydrolysis; Ions; Kinetics; Magnesium; Manganese; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nickel; Nucleotidases; Phosphoric Diester Hydrolases; Protein Structure, Tertiary; RNA Nucleotidyltransferases; Substrate Specificity | 2004 |
The structure and mechanism of serine acetyltransferase from Escherichia coli.
Topics: Acetylation; Acetyltransferases; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Escherichia coli; Histidine; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Sequence Homology, Amino Acid; Serine O-Acetyltransferase | 2004 |
Refinement of a homology model of the mu-opioid receptor using distance constraints from intrinsic and engineered zinc-binding sites.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; COS Cells; Haplorhini; Histidine; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Rats; Receptors, Opioid, mu; Sequence Alignment; Zinc | 2004 |
Chemotactic response of Helicobacter pylori to human plasma and bile.
Topics: Adaptation, Physiological; Adult; Amino Acids; Arginine; Aspartic Acid; Bile; Bile Acids and Salts; Chemotactic Factors; Chemotaxis; Glutamic Acid; Glycine; Helicobacter pylori; Histidine; Humans; In Vitro Techniques; Male; Plasma; Taurocholic Acid; Taurodeoxycholic Acid; Urea | 2004 |
Half-sandwich arene ruthenium(II)-enzyme complex.
Topics: Arginine; Aspartic Acid; Crystallography, X-Ray; Histidine; Imidazoles; Models, Chemical; Multienzyme Complexes; Muramidase; Organometallic Compounds; Proteins; Ruthenium | 2004 |
Hydrolytic polyketide shortening by ayg1p, a novel enzyme involved in fungal melanin biosynthesis.
Topics: Acetoacetates; Amino Acid Motifs; Aspartic Acid; Aspergillus fumigatus; Aspergillus oryzae; Binding Sites; Carbon; Carbon-Carbon Lyases; Catalysis; Catalytic Domain; Chromatography, High Pressure Liquid; Chromatography, Liquid; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression Regulation, Fungal; Genes, Fungal; Histidine; Hydrolysis; Kinetics; Mass Spectrometry; Melanins; Models, Chemical; Multienzyme Complexes; Mutagenesis, Site-Directed; Mutation; Naphthols; Plasmids; Pyrones; Serine; Substrate Specificity | 2004 |
A Genome-wide view of the Escherichia coli BasS-BasR two-component system implicated in iron-responses.
Topics: Aspartic Acid; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genome, Bacterial; Histidine; Iron; Lipopolysaccharides; Phosphotransferases; Signal Transduction | 2004 |
Arabidopsis response regulator, ARR22, ectopic expression of which results in phenotypes similar to the wol cytokinin-receptor mutant.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Aspartic Acid; Cytokinins; Gene Expression Regulation, Plant; Histidine; Histidine Kinase; Molecular Sequence Data; Mutation; Onions; Phenotype; Phosphorylation; Plants, Genetically Modified; Protein Kinases; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Signal Transduction; Transcription Factors; Transgenes | 2004 |
Rapid response of Arabidopsis T87 cultured cells to cytokinin through His-to-Asp phosphorelay signal transduction.
Topics: Arabidopsis; Aspartic Acid; Cells, Cultured; Cytokinins; Gene Expression Profiling; Gene Expression Regulation, Plant; Histidine; Indoleacetic Acids; Phosphorylation; Plant Physiological Phenomena; Signal Transduction; Transcription Factors | 2004 |
Negatively charged residues and hydrogen bonds tune the ligand histidine pKa values of Rieske iron-sulfur proteins.
Topics: Animals; Aspartic Acid; Burkholderia; Cattle; Computer Simulation; Electron Transport Complex III; Ferredoxins; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Iron-Sulfur Proteins; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Rhodobacter sphaeroides; Static Electricity; Thermodynamics; Titrimetry | 2004 |
ECEPE proteins: a novel family of eukaryotic cysteine proteinases.
Topics: Amino Acid Sequence; Aspartic Acid; Catalysis; Cysteine; Cysteine Endopeptidases; Eukaryotic Cells; Glutamine; Guanylate Cyclase; Histidine; Molecular Sequence Data; Papain; Sequence Homology, Amino Acid | 2004 |
Coupled sodium/glucose cotransport by SGLT1 requires a negative charge at position 454.
Topics: Animals; Aspartic Acid; Cell Membrane; Cysteine; Glucose; Histidine; Humans; Membrane Glycoproteins; Methylglucosides; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Binding; Rhodamines; Sodium; Sodium-Glucose Transporter 1; Spectrometry, Fluorescence; Xenopus laevis | 2004 |
Role of lysine-256 in Citrobacter freundii tyrosine phenol-lyase in monovalent cation activation.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cations, Monovalent; Citrobacter freundii; Enzyme Activation; Glutamic Acid; Histidine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Potassium; Protein Binding; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Tyrosine Phenol-Lyase | 2004 |
Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma.
Topics: Adult; Aging; Alleles; Asian People; Aspartic Acid; Cell Cycle Proteins; Chromatography, High Pressure Liquid; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glaucoma, Open-Angle; Heterozygote; Histidine; Humans; Intraocular Pressure; Male; Membrane Transport Proteins; Middle Aged; Mutation; Polymorphism, Genetic; Threonine; Transcription Factor TFIIIA; Tumor Necrosis Factor-alpha; Visual Fields | 2004 |
Theoretical investigations of prostatic acid phosphatase.
Topics: Acid Phosphatase; Animals; Aspartic Acid; Binding Sites; Computer Simulation; Dimerization; ErbB Receptors; Histidine; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Ligands; Models, Chemical; Models, Molecular; Peptides; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Proteins; Proteomics; Rats; Receptor, ErbB-2; Static Electricity; Thermodynamics; Tyrosine | 2005 |
Association of a common variant of the CASP8 gene with reduced risk of breast cancer.
Topics: Aspartic Acid; Breast Neoplasms; Case-Control Studies; Caspase 10; Caspase 8; Caspases; England; Female; Genetic Predisposition to Disease; Genetic Variation; Heterozygote; Histidine; Homozygote; Humans; Odds Ratio; Polymorphism, Single Nucleotide; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor | 2004 |
Kinetic analysis of YPD1-dependent phosphotransfer reactions in the yeast osmoregulatory phosphorelay system.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Cloning, Molecular; DNA-Binding Proteins; Glutathione Transferase; Histidine; Intracellular Signaling Peptides and Proteins; Models, Molecular; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylation; Protein Kinases; Protein Structure, Secondary; Recombinant Fusion Proteins; Restriction Mapping; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2005 |
Mutation analysis of the histidine residues in the glycylglycine endopeptidase ALE-1.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Conserved Sequence; Endopeptidases; Histidine; Metalloendopeptidases; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Staphylococcus; Tyrosine; Zinc | 2005 |
Identification of functional amino acids in the Nramp family by a combination of evolutionary analysis and biophysical studies of metal and proton cotransport in vivo.
Topics: Amino Acids; Asparagine; Aspartic Acid; Cadmium; Cation Transport Proteins; Cell Membrane Permeability; Cobalt; Escherichia coli Proteins; Evolution, Molecular; Ferrous Compounds; Histidine; Manganese; Metals, Heavy; Mutagenesis, Site-Directed; Protein Transport; Proto-Oncogene Proteins c-myc; Protons | 2005 |
The crystal structure of an eukaryotic iron superoxide dismutase suggests intersubunit cooperation during catalysis.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Crystallography, X-Ray; Cytosol; Dimerization; Histidine; Hydrogen Peroxide; Iron; Ligands; Models, Molecular; Molecular Sequence Data; Oxygen; Phaseolus; Protein Binding; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Sequence Homology, Amino Acid; Superoxide Dismutase | 2005 |
Crystal structure of the complex formed between a group I phospholipase A2 and a naturally occurring fatty acid at 2.7 A resolution.
Topics: Alkanes; Amino Acid Sequence; Animals; Aspartic Acid; Bungarus; Calcium; Crystallography, X-Ray; Dicarboxylic Acids; DNA, Complementary; Electrons; Fatty Acids; Histidine; Models, Molecular; Molecular Sequence Data; Phospholipases A; Phospholipases A2; Protein Folding; Protein Structure, Secondary; Sequence Homology, Amino Acid; Snake Venoms; Sodium; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway.
Topics: Alanine; Amidohydrolases; Asparagine; Aspartic Acid; Bacterial Proteins; Glutamic Acid; Gram-Negative Bacteria; Histidine; Hydrogen-Ion Concentration; Kinetics; Lipid A; Lysine; Mutagenesis, Site-Directed; Substrate Specificity; Zinc | 2005 |
Crystal structure of the protein histidine phosphatase SixA in the multistep His-Asp phosphorelay.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Crystallography, X-Ray; Escherichia coli Proteins; Histidine; Models, Molecular; Molecular Sequence Data; Phosphoprotein Phosphatases; Protein Structure, Tertiary; Sequence Alignment; Signal Transduction; Tungsten Compounds | 2005 |
Combinatorial microarray analysis revealing arabidopsis genes implicated in cytokinin responses through the His->Asp Phosphorelay circuitry.
Topics: Arabidopsis; Aspartic Acid; Cells, Cultured; Cytokinins; Databases, Genetic; Gene Expression Regulation, Plant; Histidine; Oligonucleotide Array Sequence Analysis; Phosphorylation; Plant Growth Regulators; Signal Transduction; Up-Regulation | 2005 |
Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase.
Topics: Alanine; Aldehyde-Lyases; Aldehydes; Amino Acid Substitution; Arginine; Aspartic Acid; Carboxy-Lyases; Catalysis; Decarboxylation; Enzyme Stability; Escherichia coli Proteins; Evolution, Molecular; Formaldehyde; Glutamic Acid; Histidine; Ketoses; Methylomonas; Orotidine-5'-Phosphate Decarboxylase; Ribulosephosphates; Stereoisomerism; Threonine; Valine | 2005 |
In vivo analysis of the roles of conserved aspartate and histidine residues within a complex response regulator.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Conserved Sequence; Cyanobacteria; Gene Expression Regulation, Bacterial; Histidine; Light; Light-Harvesting Protein Complexes; Phosphorylation; Phycoerythrin; Protein Kinases; Protein Structure, Secondary; Protein Structure, Tertiary; Signal Transduction | 2005 |
Hinge residue Ile260 of DNA polymerase beta is important for enzyme activity and fidelity.
Topics: Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; DNA Polymerase beta; Enzyme Activation; Enzyme Stability; Escherichia coli Proteins; Genetic Complementation Test; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Isoleucine; Lysine; Peptide Fragments; Phenotype; Protein Folding; Protein Structure, Tertiary; Rats; Substrate Specificity | 2005 |
Structure of YciI from Haemophilus influenzae (HI0828) reveals a ferredoxin-like alpha/beta-fold with a histidine/aspartate centered catalytic site.
Topics: Aspartic Acid; Bacterial Proteins; Catalysis; Catalytic Domain; Crystallography, X-Ray; Ferredoxins; Haemophilus influenzae; Histidine; Models, Molecular; Protein Folding; Protein Structure, Secondary; Sensitivity and Specificity | 2005 |
Multistress regulation in Escherichia coli: expression of osmB involves two independent promoters responding either to sigmaS or to the RcsCDB His-Asp phosphorelay.
Topics: Adaptation, Physiological; Aspartic Acid; Bacterial Outer Membrane Proteins; Bacterial Proteins; Base Sequence; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Histidine; Lipoproteins; Molecular Sequence Data; Periplasmic Proteins; Promoter Regions, Genetic; Sigma Factor; Signal Transduction; Transcription Factors | 2005 |
Constant pH molecular dynamics with proton tautomerism.
Topics: Algorithms; Animals; Aspartic Acid; Carbon; Computer Simulation; Crystallography, X-Ray; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Macromolecular Substances; Models, Biological; Models, Chemical; Models, Molecular; Models, Statistical; Molecular Conformation; Protein Conformation; Protein Structure, Tertiary; Proteins; Protons; Ribonuclease, Pancreatic; Solvents; Thermodynamics; Time Factors; Turkeys | 2005 |
Theoretical study revealing the functioning of a novel combination of catalytic motifs in histone deacetylase.
Topics: Amino Acid Motifs; Antineoplastic Agents; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Histidine; Histone Deacetylases; Models, Molecular; Protons; Water | 2005 |
Novel 3'-ribonuclease and 3'-phosphatase activities of the bacterial non-homologous end-joining protein, DNA ligase D.
Topics: Alanine; Amino Acid Sequence; Archaeal Proteins; Arginine; Aspartic Acid; Bacterial Proteins; Base Sequence; Centrifugation, Density Gradient; DNA; DNA Ligase ATP; DNA Ligases; DNA Mutational Analysis; DNA Primers; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glycerol; Histidine; Hydrolysis; Kinetics; Molecular Sequence Data; Mutation; Phosphoric Monoester Hydrolases; Protein Structure, Tertiary; Pseudomonas aeruginosa; Ribonucleases; Sequence Homology, Amino Acid; Time Factors | 2005 |
A c-KIT codon 816 mutation, D816H, in the testicular germ cell tumor: case report of a Japanese patient with bilateral testicular seminomas.
Topics: Adult; Aspartic Acid; Base Sequence; Codon; Histidine; Humans; Male; Mutation; Neoplasms, Second Primary; Proto-Oncogene Proteins c-kit; Seminoma; Testicular Neoplasms | 2005 |
Mutational and pH analysis of ionic residues in transmembrane domains of vesicular acetylcholine transporter.
Topics: Acetylcholine; Animals; Aspartic Acid; Binding Sites; Biological Transport; Blotting, Western; Cell Line; Cell Membrane; Fluorescent Antibody Technique, Direct; Histidine; Hydrogen-Ion Concentration; Lysine; Membrane Transport Proteins; Microscopy, Confocal; Mutagenesis, Site-Directed; Piperidines; Protein Structure, Tertiary; Rats; Static Electricity; Vesicular Acetylcholine Transport Proteins | 2005 |
Autochelation in dipeptide boronic acids: pH-dependent structures and equilibria of Asp-boroPro and His-boroPro by NMR spectroscopy.
Topics: Aspartic Acid; Boronic Acids; Chelating Agents; Dipeptides; Histidine; Hydrogen-Ion Concentration; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Proline; Protease Inhibitors; Protein Conformation | 2005 |
Staphylococcus aureus aminopeptidase S is a founding member of a new peptidase clan.
Topics: Aminopeptidases; Aspartic Acid; Binding Sites; Chromatography, Gel; Chromatography, Thin Layer; Cloning, Molecular; Cobalt; Crystallography, X-Ray; Dimerization; Glutamic Acid; Histidine; Ions; Ligands; Peptide Hydrolases; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrophotometry, Atomic; Staphylococcus aureus; Temperature; Ultracentrifugation; Zinc | 2005 |
Metal specificity is correlated with two crucial active site residues in Escherichia coli alkaline phosphatase.
Topics: Alkaline Phosphatase; Amino Acid Substitution; Aspartic Acid; Binding Sites; Catalysis; Cobalt; Crystallography, X-Ray; Escherichia coli Proteins; Histidine; Hydrogen-Ion Concentration; Ligands; Lysine; Magnesium; Metals; Phosphates; Tryptophan; Zinc | 2005 |
Structural basis for photo-induced protein cleavage and green-to-red conversion of fluorescent protein EosFP.
Topics: Animals; Anthozoa; Aspartic Acid; Crystallography, X-Ray; Electrons; Escherichia coli; Histidine; Isoleucine; Light; Luminescent Proteins; Models, Chemical; Models, Molecular; Peptides; Phenylalanine; Protein Conformation; Protein Processing, Post-Translational; Proteins; Red Fluorescent Protein; Spectrometry, Fluorescence; Stereoisomerism; Water; X-Rays | 2005 |
Lennard-Jones parameters for the combined QM/MM method using the B3LYP/6-31G*/AMBER potential.
Topics: Acetamides; Amino Acids; Asparagine; Aspartic Acid; Computer Simulation; Histidine; Hydrogen Bonding; Lysine; Models, Molecular; Molecular Structure; Proteins; Serine; Thermodynamics | 2005 |
Identification of residues essential for carbohydrate recognition and cation dependence of the 46-kDa mannose 6-phosphate receptor.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Carbohydrate Metabolism; Cations; Cattle; Dogs; Electron Spin Resonance Spectroscopy; Glucuronidase; Histidine; Humans; Lectins; Lysosomes; Manganese; Mice; Molecular Sequence Data; Rats; Receptors, Cell Surface; Surface Plasmon Resonance; Time Factors | 2005 |
A new kindred with pseudohypoaldosteronism type II and a novel mutation (564D>H) in the acidic motif of the WNK4 gene.
Topics: Adult; Amino Acid Motifs; Animals; Aspartic Acid; Cell Membrane; Female; Genetic Testing; Histidine; Humans; Hyperkalemia; Hypertension; Male; Mutation, Missense; Oocytes; Pedigree; Potassium Channels, Inwardly Rectifying; Protein Serine-Threonine Kinases; Pseudohypoaldosteronism; Receptors, Drug; Sodium Chloride Symporters; Sodium Radioisotopes; Xenopus laevis | 2005 |
Re: Association of a common variant of the CASP8 gene with reduced risk of breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Breast Neoplasms; Case-Control Studies; Caspase 8; Caspases; Cohort Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Germany; Histidine; Humans; Middle Aged; Odds Ratio; Risk Assessment; Risk Factors | 2005 |
X-ray structure of the R69D phosphatidylinositol-specific phospholipase C enzyme: insight into the role of calcium and surrounding amino acids in active site geometry and catalysis.
Topics: Amino Acid Sequence; Animals; Arginine; Aspartic Acid; Bacillus cereus; Bacillus thuringiensis; Binding Sites; Calcium; Catalysis; Crystallization; Crystallography, X-Ray; Histidine; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Molecular Sequence Data; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Rats; Stereoisomerism | 2005 |
Apparent pKa shifts of titratable residues at high denaturant concentration and the impact on protein stability.
Topics: Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Glutamic Acid; Guanidine; Histidine; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Protein Folding; Proteins; Sensitivity and Specificity; Titrimetry; Urea | 2005 |
Differential effects of the Zn-His-Bkb vs Zn-His-[Asp/Glu] triad on Zn-core stability and reactivity.
Topics: Aspartic Acid; Catalytic Domain; Electron Transport; Enzymes; Glutamic Acid; Histidine; Humans; Ligands; Metalloproteins; Protein Conformation; Zinc | 2005 |
Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Brain; Catalysis; Catalytic Domain; Cattle; Chlorocebus aethiops; Chromatography; COS Cells; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Immunoblotting; Kidney; Lysosomes; Macrophages; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Open Reading Frames; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases A; Phospholipases A2; Phospholipids; Plasmids; Pulmonary Surfactants; Rats; Sequence Homology, Amino Acid; Serine; Surface-Active Agents; Transfection | 2005 |
Localization of a substrate binding domain of the human reduced folate carrier to transmembrane domain 11 by radioaffinity labeling and cysteine-substituted accessibility methods.
Topics: Amino Acid Sequence; Anions; Aspartic Acid; Blotting, Western; Cell Line; Cell Membrane; Cysteine; Cytosol; Folic Acid; Glutamine; HeLa Cells; Histidine; Humans; K562 Cells; Leucovorin; Membrane Transport Proteins; Mesylates; Microscopy, Fluorescence; Molecular Sequence Data; Mutagenesis; Mutation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Reduced Folate Carrier Protein; Sulfhydryl Reagents; Temperature; Thiocyanates; Time Factors; Transfection; Tyrosine | 2005 |
Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease.
Topics: Aspartic Acid; Binding Sites; Coenzyme A; Crystallization; Crystallography, X-Ray; Cysteine; Escherichia coli; Ferrous Compounds; Histidine; Humans; Ketoglutaric Acids; Mixed Function Oxygenases; Models, Molecular; Mutation; Peroxisomes; Phytanic Acid; Protein Binding; Protein Structure, Secondary; Recombinant Proteins; Refsum Disease; Structure-Activity Relationship; Transfection | 2005 |
Lineage-specific variations of congruent evolution among DNA sequences from three genomes, and relaxed selective constraints on rbcL in Cryptomonas (Cryptophyceae).
Topics: Asparagine; Aspartic Acid; Bayes Theorem; Codon; Cryptophyta; Cysteine; DNA; DNA, Ribosomal; Evolution, Molecular; Genome; Histidine; Likelihood Functions; Phenylalanine; Photosynthesis; Phylogeny; Plastids; Polymerase Chain Reaction; Ribulose-Bisphosphate Carboxylase; Sequence Analysis, DNA; Tyrosine | 2005 |
A conserved histidine-aspartate pair is required for exovinyl reduction of biliverdin by a cyanobacterial phycocyanobilin:ferredoxin oxidoreductase.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Bile Pigments; Biliverdine; Biochemistry; Catalysis; Conserved Sequence; Cyanobacteria; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Electrons; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oxidoreductases; Protons; Sequence Homology, Amino Acid; Spectrophotometry; Temperature | 2006 |
How gastric lipase, an interfacial enzyme with a Ser-His-Asp catalytic triad, acts optimally at acidic pH.
Topics: Animals; Aspartic Acid; Dogs; Histidine; Hydrogen-Ion Concentration; Kinetics; Lipase; Plants, Genetically Modified; Recombinant Proteins; Serine; Stomach; Zea mays | 2006 |
Linker chains of the gigantic hemoglobin of the earthworm Lumbricus terrestris: primary structures of linkers L2, L3, and L4 and analysis of the connectivity of the disulfide bonds in linker L1.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Binding Sites; Calcium; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Dithiothreitol; DNA, Complementary; Glutamic Acid; Heme; Hemoglobins; Histidine; Humans; Ligands; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Oligochaeta; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Receptors, LDL; RNA, Messenger; Sequence Homology, Amino Acid; Sodium Dodecyl Sulfate; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase | 2006 |
Calorimetric investigation of protein/amino acid interactions in the solid state.
Topics: Amino Acids; Antibodies; Arginine; Aspartic Acid; Calorimetry, Differential Scanning; Circular Dichroism; Deoxyribonuclease I; Enzyme Stability; Freeze Drying; Histidine; Protein Denaturation; Proteins; Recombinant Proteins; Solutions; Thermodynamics | 2006 |
Structure and activity of two metal ion-dependent acetylxylan esterases involved in plant cell wall degradation reveals a close similarity to peptidoglycan deacetylases.
Topics: Acetylesterase; Amidohydrolases; Aspartic Acid; Binding Sites; Carbohydrate Metabolism; Carbohydrates; Catalysis; Cell Wall; Chitin; Clostridium thermocellum; Cobalt; Crystallography, X-Ray; Dimerization; Escherichia coli; Histidine; Ions; Ligands; Metals; Models, Chemical; Models, Molecular; Models, Statistical; Nickel; Peptidoglycan; Plants; Protein Conformation; Protein Structure, Tertiary; Streptomyces lividans; Structure-Activity Relationship; Xylans | 2006 |
Enzyme dynamics along the reaction coordinate: critical role of a conserved residue.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Enzyme Stability; Histidine; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Conformation; Ribonuclease, Pancreatic | 2006 |
Mini-alphaB-crystallin: a functional element of alphaB-crystallin with chaperone-like activity.
Topics: alpha-Crystallin B Chain; Amino Acid Sequence; Aspartic Acid; D-Aspartic Acid; Histidine; Kynurenine; Molecular Chaperones; Molecular Sequence Data; Peptides; Protein Denaturation; Time Factors | 2006 |
Effects of reversing the protein positive charge in the proximity of the flavin N(1) locus of choline oxidase.
Topics: Alcohol Oxidoreductases; Aspartic Acid; Betaine; Catalysis; Flavins; Histidine; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Potentiometry; Protein Binding; Spectrophotometry; Sulfites | 2006 |
The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary hemochromatosis.
Topics: Adult; Aged; Aspartic Acid; Cysteine; Fatty Liver; Female; Genetic Predisposition to Disease; Glucose Intolerance; Hemochromatosis; Hepatitis; Heterozygote; Histidine; Homozygote; Humans; Iron Overload; Liver Cirrhosis; Male; Metabolic Syndrome; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prospective Studies; Risk Factors; Tyrosine | 2006 |
Low-barrier hydrogen bond hypothesis in the catalytic triad residue of serine proteases: correlation between structural rearrangement and chemical shifts in the acylation process.
Topics: Acylation; Amino Acid Sequence; Aspartic Acid; Catalytic Domain; Histidine; Hydrogen Bonding; Nuclear Magnetic Resonance, Biomolecular; Serine Endopeptidases; Thermodynamics; Trypsin | 2006 |
Structure of the human multidrug resistance protein 1 nucleotide binding domain 1 bound to Mg2+/ATP reveals a non-productive catalytic site.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Dimerization; Histidine; Humans; Magnesium; Models, Molecular; Molecular Sequence Data; Nucleotides; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Structural Homology, Protein | 2006 |
Mechanistic study on the oxidation of anthocyanidin synthase by quantum mechanical calculation.
Topics: Arabidopsis; Aspartic Acid; Biochemistry; Evolution, Molecular; Histidine; Ketones; Models, Chemical; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Oxygen; Oxygenases; Quantum Theory; Substrate Specificity | 2006 |
Mutagenic definition of a papain-like catalytic triad, sufficiency of the N-terminal domain for single-site core catalytic enzyme acylation, and C-terminal domain for augmentative metal activation of a eukaryotic phytochelatin synthase.
Topics: Acylation; Amino Acid Sequence; Aminoacyltransferases; Arabidopsis; Aspartic Acid; Binding Sites; Cadmium; Catalysis; Cysteine; Enzyme Activation; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Papain; Protein Structure, Tertiary; Sequence Homology, Amino Acid | 2006 |
A magnetic biomimetic nanocatalyst for cleaving phosphoester and carboxylic ester bonds under mild conditions.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Catalysis; Esters; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Molecular Mimicry; Molecular Structure; Nanotubes; Organophosphorus Compounds | 2006 |
The crystal structure of Deinococcus radiodurans Dps protein (DR2263) reveals the presence of a novel metal centre in the N terminus.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Crystallography, X-Ray; Deinococcus; DNA-Binding Proteins; Glutamic Acid; Histidine; Iron; Ligands; Models, Molecular; Molecular Sequence Data; Sequence Alignment; Zinc | 2006 |
Engineering ATPase activity in the isolated ABC cassette of human TAP1.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP-Binding Cassette Transporters; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Engineering; Protein Structure, Tertiary; Sequence Homology, Amino Acid | 2006 |
Identification by Mn2+ rescue of two residues essential for the proton transfer of tRNase Z catalysis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Base Sequence; Catalysis; Catalytic Domain; Cations, Divalent; Endoribonucleases; Histidine; Manganese; Metals; Molecular Sequence Data; Protons; RNA Precursors; RNA, Transfer; Thermotoga maritima | 2006 |
Direct NMR resonance assignments of the active site histidine residue in Escherichia coli thioesterase I/protease I/lysophospholipase L1.
Topics: Aspartic Acid; Binding Sites; Catalysis; Escherichia coli; Escherichia coli Proteins; Histidine; Lysophospholipase; Magnetic Resonance Spectroscopy; Molecular Structure; Mutation; Periplasmic Proteins | 2006 |
The effect of some osmolytes on the activity and stability of mushroom tyrosinase.
Topics: Agaricus; Amino Acids; Aspartic Acid; Enzyme Stability; Fungal Proteins; Histidine; Kinetics; Monophenol Monooxygenase; Osmosis; Phenylalanine; Protein Denaturation; Protein Structure, Secondary; Protein Structure, Tertiary; Temperature; Trehalose | 2006 |
A new class of signal transducer in His-Asp phosphorelay systems.
Topics: Amino Acid Sequence; Anion Transport Proteins; Aspartic Acid; Bacterial Proteins; Biological Transport, Active; Genome, Bacterial; Histidine; Models, Biological; Molecular Sequence Data; Nitrates; Phosphorylation; Sequence Homology, Amino Acid; Signal Transduction; Synechococcus | 2006 |
Catalytic site modifications of TAP1 and TAP2 and their functional consequences.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP Binding Cassette Transporter, Subfamily B, Member 3; ATP-Binding Cassette Transporters; Baculoviridae; Binding Sites; Catalytic Domain; Cell Line, Tumor; Genetic Vectors; Glutamic Acid; Glutamine; Histidine; Humans; Nucleotides; Protein Transport | 2006 |
HFE H63D variant and leukemia susceptibility.
Topics: Aspartic Acid; Genetic Predisposition to Disease; Histidine; Humans; Leukemia; Mutation | 2006 |
HFE gene mutations in patients with acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Female; Genotype; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Leukemia; Male; Membrane Proteins; Middle Aged; Mutation | 2006 |
Developments in the characterisation of the catalytic triad of alpha-chymotrypsin: Effect of the protonation state of Asp102 on the 1H NMR signals of His57.
Topics: Animals; Aspartic Acid; Biochemistry; Catalytic Domain; Cattle; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Pancreas; Protein Conformation; Protons | 2007 |
Highly conserved residues Asp-197 and His-250 in Agp1 phytochrome control the proton affinity of the chromophore and Pfr formation.
Topics: Agrobacterium tumefaciens; Aspartic Acid; Bacterial Proteins; Chromatography; Cloning, Molecular; Conserved Sequence; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Light; Molecular Conformation; Mutation; Phytochrome; Ultraviolet Rays | 2007 |
The glutamate-dependent acid resistance system in Escherichia coli: essential and dual role of the His-Asp phosphorelay RcsCDB/AF.
Topics: Acids; Adaptation, Physiological; Aspartic Acid; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Glutamate Decarboxylase; Histidine; Multienzyme Complexes; Phosphoprotein Phosphatases; Phosphorylation; Phosphotransferases; Protein Kinases; Transcription Factors | 2007 |
Roles of putative His-to-Asp signaling modules HPT-1 and RRG-2, on viability and sensitivity to osmotic and oxidative stresses in Neurospora crassa.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Aminoimidazole Carboxamide; Aspartic Acid; Fungal Proteins; Fungicides, Industrial; Histidine; Histidine Kinase; Hydantoins; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Neurospora crassa; Osmotic Pressure; Oxidative Stress; Point Mutation; Protein Kinases; Signal Transduction | 2007 |
The carboxylate shift in zinc enzymes: a computational study.
Topics: Aspartic Acid; Carboxylic Acids; Catalytic Domain; Computational Biology; Crystallography, X-Ray; Cysteine; Electron Transport; Enzymes; Glutamic Acid; Histidine; Ligands; Metalloproteins; Oxygen; Protein Conformation; Zinc | 2007 |
Metal ligand substitution and evidence for quinone formation in taurine/alpha-ketoglutarate dioxygenase.
Topics: Ascorbic Acid; Aspartic Acid; Histidine; Kinetics; Ligands; Mixed Function Oxygenases; Models, Molecular; Mutagenesis, Site-Directed; Spectrophotometry, Infrared; Structure-Activity Relationship | 2007 |
Loss of ATP hydrolysis activity by CcmAB results in loss of c-type cytochrome synthesis and incomplete processing of CcmE.
Topics: Adenosine Triphosphate; Amino Acid Motifs; Aspartic Acid; ATP-Binding Cassette Transporters; Bacterial Outer Membrane Proteins; Cytochromes c; Escherichia coli; Escherichia coli Proteins; Heme; Hemeproteins; Histidine; Hydrolysis; Lysine; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Protein Subunits; Sequence Deletion | 2007 |
The SskA and SrrA response regulators are implicated in oxidative stress responses of hyphae and asexual spores in the phosphorelay signaling network of Aspergillus nidulans.
Topics: Aspartic Acid; Aspergillus nidulans; Blotting, Southern; Catalase; Culture Media; DNA Primers; Genes, Fungal; Histidine; Hydrogen Peroxide; Hyphae; In Situ Hybridization; Mutation; Oxidants; Oxidative Stress; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Spores, Fungal; Transformation, Genetic | 2007 |
Mechanistic investigations of the dehydration reaction of lacticin 481 synthetase using site-directed mutagenesis.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Bacteriocins; Desiccation; Enzymes; Histidine; Lysine; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Substrate Specificity; Tyrosine | 2007 |
Chloroplast His-to-Asp signal transduction: a potential mechanism for plastid gene regulation in Heterosigma akashiwo (Raphidophyceae).
Topics: Algal Proteins; Aspartic Acid; Chloroplasts; Chrysophyta; Gene Expression Regulation; Histidine; Signal Transduction; Transcription Factors | 2007 |
Affinity purification of plasmid DNA directly from crude bacterial cell lysates.
Topics: Aspartic Acid; Bacteria; Bacterial Proteins; Chromatography, Affinity; DNA, Superhelical; Escherichia coli; Escherichia coli Proteins; Freeze Drying; Green Fluorescent Proteins; Histidine; Isopropyl Thiogalactoside; Lac Repressors; Plasmids; Recombinant Fusion Proteins; Repressor Proteins; Reproducibility of Results; Ribonuclease, Pancreatic; Sepharose | 2007 |
Clinical features associated with an Asp380His Myocilin mutation in a US family with primary open-angle glaucoma.
Topics: Adult; Aspartic Acid; Chromatography, High Pressure Liquid; Cytoskeletal Proteins; DNA Mutational Analysis; Eye Proteins; Female; Glaucoma, Open-Angle; Glycoproteins; Histidine; Humans; Intraocular Pressure; Male; Middle Aged; Pedigree; Phenotype; Point Mutation; Polymerase Chain Reaction; Trabeculectomy | 2007 |
An atypical receiver domain controls the dynamic polar localization of the Myxococcus xanthus social motility protein FrzS.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Conserved Sequence; Crystallography; Histidine; Magnesium; Membrane Proteins; Methyl-Accepting Chemotaxis Proteins; Molecular Sequence Data; Mutation; Myxococcus xanthus; Phosphorylation; Protein Structure, Secondary; Protein Structure, Tertiary; Tyrosine | 2007 |
What is the active species of cytochrome P450 during camphor hydroxylation? QM/MM studies of different electronic states of compound I and of reduced and oxidized iron-oxo intermediates.
Topics: Aspartic Acid; Camphor; Computational Biology; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Electrons; Free Radicals; Heme; Histidine; Hydroxylation; Iron; Oxidation-Reduction; Protons; Quantum Theory | 2007 |
Effect of Asp69 and Arg310 on the pK of His68, a key catalytic residue of adenylosuccinate lyase.
Topics: Adenylosuccinate Lyase; Amino Acid Sequence; Amino Acid Substitution; Arginine; Aspartic Acid; Bacillus subtilis; Catalytic Domain; Circular Dichroism; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Sequence Alignment | 2007 |
The determination of protonation states in proteins.
Topics: Aspartic Acid; Concanavalin A; Crystallography, X-Ray; Glutamic Acid; Hirudins; Histidine; Hydrogen Bonding; Models, Molecular; Peptide Fragments; Protein Structure, Tertiary; Proteins; Protons; Thrombin | 2007 |
Structural basis for recognition of high mannose type glycoproteins by mammalian transport lectin VIP36.
Topics: Animals; Asparagine; Aspartic Acid; Calcium; Carbohydrate Conformation; Carbohydrate Sequence; Carbohydrates; Crystallography, X-Ray; Dogs; Glycoproteins; Histidine; Ligands; Mannose; Mannose-Binding Lectins; Membrane Transport Proteins; Molecular Sequence Data | 2007 |
Polymerase-catalyzed synthesis of DNA from phosphoramidate conjugates of deoxynucleotides and amino acids.
Topics: Adenosine Monophosphate; Amides; Amino Acids; Aspartic Acid; Catalysis; Deoxyadenine Nucleotides; DNA; DNA Primers; DNA-Directed DNA Polymerase; Histidine; HIV; Models, Molecular; Phosphoric Acids; RNA-Directed DNA Polymerase; Stereoisomerism | 2007 |
The effect of deuteration on protein structure: a high-resolution comparison of hydrogenous and perdeuterated haloalkane dehalogenase.
Topics: Aspartic Acid; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Deuterium; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolases; Protein Conformation; X-Ray Diffraction; Xanthobacter | 2007 |
Structural characterization of the zinc binding domain in cytosolic PSD-95 interactor (cypin): Role of zinc binding in guanine deamination and dendrite branching.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Carrier Proteins; Cells, Cultured; Crystallography, X-Ray; Databases, Protein; Dendrites; Female; Guanine Deaminase; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurons; Protein Structure, Tertiary; Rats; Sequence Alignment; Zinc | 2008 |
An Iranian child with HbQ-Iran [alpha75 (EF4) Asp-->His]/-alpha3.7 kb/IVSII.1 G-->A: first report.
Topics: alpha-Thalassemia; Amino Acid Substitution; Aspartic Acid; beta-Thalassemia; Child, Preschool; Hemoglobins, Abnormal; Histidine; Humans; Male; Mutation | 2007 |
Roles of active site residues and the HUH motif of the F plasmid TraI relaxase.
Topics: Amino Acid Motifs; Aspartic Acid; Binding Sites; Crystallography, X-Ray; DNA Helicases; DNA, Single-Stranded; Escherichia coli Proteins; Histidine; Kinetics; Models, Molecular; Molecular Conformation; Mutagenesis; Plasmids; Protein Binding; Protein Structure, Tertiary | 2007 |
In vitro analysis of His-Asp phosphorelays in Aspergillus nidulans: the first direct biochemical evidence for the existence of His-Asp phosphotransfer systems in filamentous fungi.
Topics: Aspartic Acid; Aspergillus nidulans; Fungal Proteins; Histidine; Histidine Kinase; In Vitro Techniques; Models, Biological; Phosphorylation; Protein Kinases | 2007 |
Identification of aspartic acid and histidine residues mediating the reaction mechanism and the substrate specificity of the human UDP-glucuronosyltransferases 1A.
Topics: Aspartic Acid; Catalysis; Glucuronic Acid; Glucuronosyltransferase; Histidine; Humans; Mutagenesis, Site-Directed; Phenols; Substrate Specificity; Xenobiotics | 2007 |
Candidate amino acids involved in H+ gating of acid-sensing ion channel 1a.
Topics: Acid Sensing Ion Channels; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Aspartic Acid; Binding Sites; Calcium; Female; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Ion Channel Gating; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Nerve Tissue Proteins; Oocytes; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Sodium Channels; Structure-Activity Relationship; Xenopus laevis | 2008 |
[Preparation of metal chelate affinity chromatographic medium and its application in the purification of 6 x histidine-tagged protein].
Topics: Aspartic Acid; Chelating Agents; Chromatography, Affinity; Epoxy Compounds; Histidine; Polymers; Recombinant Fusion Proteins; Sepharose | 2007 |
Improvement of the cold storage of blood vessels with a vascular preservation solution. Study in porcine aortic segments.
Topics: Adenosine; Alanine; Allopurinol; Animals; Aorta; Aspartic Acid; Buffers; Cell Survival; Citrates; Cold Temperature; Deferoxamine; Endothelial Cells; Glucose; Glutathione; Glycine; Histidine; Hydrogen-Ion Concentration; Insulin; Iron; Iron Chelating Agents; Mannitol; Membrane Potential, Mitochondrial; Mitochondria; Organ Preservation; Organ Preservation Solutions; Platelet Adhesiveness; Potassium Chloride; Procaine; Raffinose; Rewarming; Swine; Time Factors | 2008 |
A novel ATP1A2 gene mutation in an Irish familial hemiplegic migraine kindred.
Topics: Aspartic Acid; Calcium Channels; Chromosome Mapping; Chromosomes, Human, Pair 1; DNA Mutational Analysis; Exons; Family Health; Female; Gene Frequency; Genetic Testing; Histidine; Humans; Ireland; Male; Migraine with Aura; Mutation; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Sodium Channels; Sodium-Potassium-Exchanging ATPase | 2008 |
Generation of nucleophilic character in the Cys25/His159 ion pair of papain involves Trp177 but not Asp158.
Topics: Aspartic Acid; Cysteine; Histidine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Papain; Spectrometry, Mass, Electrospray Ionization; Static Electricity; Tryptophan | 2008 |
Breast cancer-associated mutations in metalloprotease disintegrin ADAM12 interfere with the intracellular trafficking and processing of the protein.
Topics: ADAM Proteins; ADAM12 Protein; Animals; Aspartic Acid; Biotinylation; Blotting, Western; Breast Neoplasms; Cell Movement; Female; Fluorescent Antibody Technique; Glutamic Acid; Glycine; Histidine; Humans; Immunoprecipitation; Leucine; Membrane Proteins; Mice; Mutation; Phenylalanine | 2008 |
Protonation of the proximal histidine ligand in heme peroxidases.
Topics: Aspartic Acid; Heme; Histidine; Ligands; Models, Chemical; Peroxidase; Protons; Quantum Theory; Solvents; Thermodynamics | 2008 |
HFE gene mutations in a population of Italian Parkinson's disease patients.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Cysteine; DNA Mutational Analysis; Female; Gene Frequency; Genotype; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Italy; Male; Membrane Proteins; Middle Aged; Mutation; Parkinson Disease; Serine | 2008 |
Post-translational modification of cellular proteins during Leishmania donovani differentiation.
Topics: Animals; Asparagine; Aspartic Acid; Cell Differentiation; Chromatography, Liquid; Glutamic Acid; Glycosylation; Histidine; Humans; Leishmania donovani; Macrophages; Mass Spectrometry; Phosphorylation; Protein Processing, Post-Translational; Proteomics | 2008 |
Which factors determine the acidity of the phytochromobilin chromophore of plant phytochrome?
Topics: Absorption; Aspartic Acid; Biliverdine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Light; Phytochrome; Plants; Quantum Theory; Water | 2008 |
Identification of putative active site residues of ACAT enzymes.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Chlorocebus aethiops; CHO Cells; Cricetinae; Cricetulus; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Protein Folding; Sequence Alignment; Serine; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Tyrosine | 2008 |
Roles of histidines 154 and 189 and aspartate 139 in the active site of serine acetyltransferase from Haemophilus influenzae.
Topics: Amino Acid Substitution; Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Deuterium; Haemophilus influenzae; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Serine O-Acetyltransferase; Solvents | 2008 |
Atomic constraints between the voltage sensor and the pore domain in a voltage-gated K+ channel of known structure.
Topics: Alanine; Allosteric Regulation; Amino Acid Sequence; Animals; Arginine; Aspartic Acid; Binding Sites; Cadmium; Computer Simulation; Energy Transfer; Histidine; Ion Channel Gating; Kv1.2 Potassium Channel; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Static Electricity; Xenopus; Zinc | 2008 |
Susceptibility to DYT1 dystonia in European patients is modified by the D216H polymorphism.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Child; Dystonia; Genetic Predisposition to Disease; Histidine; Humans; Middle Aged; Molecular Chaperones; Polymorphism, Single Nucleotide; White People | 2008 |
Significant association of ABCG8:D19H gene polymorphism with hypercholesterolemia and insulin resistance.
Topics: Adult; Aged; Amino Acid Substitution; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Cholesterol, LDL; Female; Histidine; Humans; Hypercholesterolemia; Insulin Resistance; Male; Middle Aged; Polymorphism, Genetic; Risk Factors | 2008 |
Molecular mechanism of Zn2+ agonism in the extracellular domain of GPR39.
Topics: Alanine; Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Cations, Divalent; Cell Line; Histidine; Humans; Mice; Protein Structure, Tertiary; Rats; Receptors, G-Protein-Coupled; Zinc | 2008 |
Possible mechanisms contributing to oxidative inactivation of activated protein C: molecular dynamics study.
Topics: Allosteric Regulation; Aspartic Acid; Binding Sites; Computer Simulation; Cyanogen Bromide; Enzyme Activation; Enzyme Stability; Histidine; Humans; Hydrogen Bonding; Hydrogen Peroxide; Hypochlorous Acid; Methionine; Models, Molecular; Oxidants; Oxidation-Reduction; Protein Binding; Protein C; Protein Conformation; Recombinant Proteins | 2008 |
Abundance changes of the response regulator RcaC require specific aspartate and histidine residues and are necessary for normal light color responsiveness.
Topics: Aspartic Acid; Bacterial Proteins; Cyanobacteria; Gene Expression Regulation, Bacterial; Histidine; Immunoblotting; Kinetics; Light; Phosphorylation; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Functional analyses for tRNase Z variants: an aspartate and a histidine in the active site are essential for the catalytic activity.
Topics: Amino Acid Substitution; Aspartic Acid; Bacillus subtilis; Bacterial Proteins; Catalysis; Catalytic Domain; Endoribonucleases; Escherichia coli; Histidine; Manganese; Thermotoga maritima | 2008 |
Association of MUTYH Gln324His and APEX1 Asp148Glu with colorectal cancer and smoking in a Japanese population.
Topics: Aged; Asian People; Aspartic Acid; Case-Control Studies; Colorectal Neoplasms; DNA Glycosylases; DNA-(Apurinic or Apyrimidinic Site) Lyase; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Glutamine; Histidine; Humans; Male; Middle Aged; Polymorphism, Genetic; Smoking | 2008 |
Hereditary haemochromatosis gene (HFE) H63D mutation shows an association with abnormal sperm motility.
Topics: Adolescent; Adult; Age Distribution; Amino Acid Substitution; Aspartic Acid; Genetic Predisposition to Disease; Genotype; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Infertility, Male; Male; Membrane Proteins; Mutation; Sperm Motility | 2009 |
The role of amino acids in the long-distance transport of La and Y in the xylem sap of tomato.
Topics: Amino Acids; Aspartic Acid; Biological Transport; Chromatography, High Pressure Liquid; Glutamic Acid; Histidine; Lanthanum; Solanum lycopersicum; Tryptophan; Xylem; Yttrium | 2009 |
Binding of a noncovalent inhibitor exploiting the S' region stabilizes the hepatitis C virus NS3 protease conformation in the absence of cofactor.
Topics: Amides; Aspartic Acid; Carrier Proteins; Catalysis; Catalytic Domain; Crystallography, X-Ray; Enzyme Stability; Histidine; Hydrogen Bonding; Intracellular Signaling Peptides and Proteins; Kinetics; Models, Molecular; Protease Inhibitors; Protein Structure, Secondary; Protein Structure, Tertiary; Titrimetry; Viral Nonstructural Proteins; Viral Proteins; Water | 2009 |
A summary of the measured pK values of the ionizable groups in folded proteins.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Isoelectric Point; Nuclear Magnetic Resonance, Biomolecular; Protein Folding; Protein Structure, Tertiary; Proteins; Titrimetry | 2009 |
Why do cysteine dioxygenase enzymes contain a 3-His ligand motif rather than a 2His/1Asp motif like most nonheme dioxygenases?
Topics: Amino Acid Motifs; Aspartic Acid; Biocatalysis; Catalytic Domain; Cysteine; Cysteine Dioxygenase; Heme; Histidine; Humans; Ligands; Models, Chemical; Models, Molecular | 2009 |
Hb North York [beta 117(G19)His-->Asp]: a new beta chain hemoglobin variant.
Topics: Adult; Aspartic Acid; beta-Globins; DNA Mutational Analysis; Female; Hemoglobins, Abnormal; Histidine; Humans; Iran; Mutation, Missense | 2009 |
The p.Asp216His TOR1A allele effect is not found in the French population.
Topics: Alleles; Aspartic Acid; DNA Mutational Analysis; Dystonic Disorders; France; Gene Frequency; Histidine; Humans; Molecular Chaperones; Polymorphism, Single Nucleotide | 2009 |
Four spatial points that define enzyme families.
Topics: Amino Acid Sequence; Aspartic Acid; Catalysis; Databases, Protein; Enzymes; Histidine; Protein Conformation; Serine | 2009 |
Identification of the Zn2+ binding site and mode of operation of a mammalian Zn2+ transporter.
Topics: Aspartic Acid; Binding Sites; Cation Transport Proteins; Cells, Cultured; Cytoplasm; Histidine; Humans; Kidney; Models, Molecular; Mutagenesis, Site-Directed; Neoplasm Proteins; Protein Conformation; Protons; trans-Golgi Network; Vacuolar Proton-Translocating ATPases; Zinc | 2009 |
APH1 polar transmembrane residues regulate the assembly and activity of presenilin complexes.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid; Catalysis; Cells, Cultured; Conserved Sequence; Endopeptidases; Fibroblasts; Histidine; Humans; Membrane Proteins; Mice; Molecular Sequence Data; Multiprotein Complexes; Mutagenesis, Site-Directed; Peptide Hydrolases; Presenilins; Protein Structure, Tertiary; Transfection | 2009 |
Self-guided Langevin dynamics study of regulatory interactions in NtrC.
Topics: Aspartic Acid; Bacterial Proteins; Catalytic Domain; Computer Simulation; Histidine; Models, Molecular; Phosphorylation; PII Nitrogen Regulatory Proteins; Protein Conformation; Salmonella typhimurium | 2009 |
Molecular recognition of the palmitoylation substrate Vac8 by its palmitoyltransferase Pfa3.
Topics: Acetyltransferases; Acyltransferases; Amino Acid Sequence; Aspartic Acid; Cysteine; Histidine; Lipoylation; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; src Homology Domains; Vacuoles; Vesicular Transport Proteins | 2009 |
Site-directed mutagenesis, kinetic and inhibition studies of aspartate ammonia lyase from Bacillus sp. YM55-1.
Topics: Amino Acid Substitution; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Bacillus; Bacterial Proteins; Binding Sites; Catalysis; Catalytic Domain; Circular Dichroism; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Malates; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Nitro Compounds; Propionates; Protein Structure, Tertiary; Serine; Substrate Specificity; Threonine | 2009 |
Crystal structure of human mitochondrial acyl-CoA thioesterase (ACOT2).
Topics: Amino Acid Sequence; Aspartic Acid; Catalytic Domain; Crystallography, X-Ray; Histidine; Humans; Mitochondria; Molecular Sequence Data; Protein Structure, Tertiary; Serine; Thiolester Hydrolases | 2009 |
Structural adaptability of zinc binding sites: different structures in partially, fully, and heavy-metal loaded states.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Cysteine; Glutamic Acid; Histidine; Metalloproteins; Molecular Sequence Data; Molecular Structure; Zinc; Zinc Fingers | 2009 |
Role of intramembrane polar residues in the YgfO xanthine permease: HIS-31 and ASN-93 are crucial for affinity and specificity, and ASP-304 and GLU-272 are irreplaceable.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Escherichia coli K12; Escherichia coli Proteins; Evolution, Molecular; Glutamic Acid; Histidine; Membrane Transport Proteins; Models, Biological; Mutation, Missense; Nucleobase Transport Proteins; Protein Structure, Secondary; Substrate Specificity; Xanthine | 2009 |
Association and impact of XPG Asp 1104 His gene polymorphism in HIV 1 disease progression to AIDS among north Indian HIV seropositive individuals.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Amino Acid Substitution; Aspartic Acid; Case-Control Studies; Disease Progression; DNA-Binding Proteins; Endonucleases; Female; Gene Frequency; Genetic Predisposition to Disease; Histidine; HIV Seropositivity; HIV-1; Humans; India; Male; Marital Status; Middle Aged; Nuclear Proteins; Polymorphism, Single Nucleotide; Spouses; Transcription Factors; Young Adult | 2010 |
AMINO ACID COMPOSITION OF HIGHLY PURIFIED VIRAL PARTICLES OF INFLUENZA A AND B.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Humans; Influenza, Human; Isoleucine; Leucine; Lysine; Methionine; Orthomyxoviridae; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine; Virion | 1947 |
Stringency of the 2-His-1-Asp active-site motif in prolyl 4-hydroxylase.
Topics: Alanine; Amino Acid Motifs; Aspartic Acid; Carbon; Catalysis; Catalytic Domain; Collagen; Glycine; Heme; Histidine; Humans; Hydrogen; Iron; Ligands; Procollagen-Proline Dioxygenase | 2009 |
Is Asp-His-Ser/Thr-Trp tetrad hydrogen-bond network important to WD40-repeat proteins: a statistical and theoretical study.
Topics: Amino Acid Sequence; Aspartic Acid; Crystallography, X-Ray; Databases, Protein; Histidine; Humans; Hydrogen Bonding; Molecular Sequence Data; Molecular Structure; Protein Conformation; Proteins; Serine; Threonine; Tryptophan | 2010 |
Structural determinants of the high affinity extracellular zinc binding site on Cav3.2 T-type calcium channels.
Topics: Animals; Aspartic Acid; Binding Sites; Calcium Channels, T-Type; Electrophysiology; Female; Histidine; Inhibitory Concentration 50; Models, Molecular; Mutation; Oocytes; Oxidation-Reduction; Rats; Xenopus; Zinc | 2010 |
Vohwinkel Syndrome secondary to missense mutation D66H in GJB2 gene (connexin 26) can include epileptic manifestations.
Topics: Aspartic Acid; Connexin 26; Connexins; Epilepsy; Histidine; Humans; Keratoderma, Palmoplantar; Male; Mutation, Missense; Young Adult | 2010 |
X-ray absorption studies of Zn(2+)-binding sites in Escherichia coli transhydrogenase and its betaH91K mutant.
Topics: Amino Acid Substitution; Aspartic Acid; Binding Sites; Cysteine; Escherichia coli Proteins; Glutamic Acid; Histidine; Models, Molecular; Mutation; NADP Transhydrogenases; Protein Binding; Protein Structure, Tertiary; Spectrometry, X-Ray Emission; Zinc | 2010 |
A model study of the efficiency of the Asp-His-Ser triad.
Topics: Amino Acid Motifs; Aspartic Acid; Histidine; Kinetics; Models, Chemical; Models, Molecular; Quantum Theory; Serine; Serine Endopeptidases | 2010 |
Synthesis of novel dendrimers having aspartate grafts and their ability to enhance the aqueous solubility of model drugs.
Topics: Aspartic Acid; Dendrimers; Drug Carriers; Histidine; Hydrogen-Ion Concentration; Methotrexate; Naproxen; Peptides; Pharmaceutical Preparations; Solubility; Surface Properties; Temperature; Water | 2010 |
Residue N84 of yeast cystathionine beta-synthase is a determinant of reaction specificity.
Topics: Alanine; Aspartic Acid; Catalysis; Cystathionine; Cystathionine beta-Synthase; Histidine; Homocysteine; Kinetics; Mutation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Substrate Specificity; Time Factors; Tryptophan | 2010 |
Chemical fragments that hydrogen bond to Asp, Glu, Arg, and His side chains in protein binding sites.
Topics: Arginine; Aspartic Acid; Binding Sites; Databases, Factual; Glutamic Acid; Histidine; Hydrogen Bonding; Ligands; Models, Molecular; Molecular Structure | 2010 |
Energy compensation mechanism for charge-separated protonation states in aspartate-histidine amino acid residue pairs.
Topics: Animals; Aspartic Acid; Biocatalysis; Cattle; Electron Transport Complex IV; Histidine; Hydrogen Bonding; Protein Structure, Tertiary; Protons; Static Electricity; Thermodynamics | 2010 |
Studies on the catalytic mechanism of a glutamic peptidase.
Topics: Aspartic Acid; Carbon; Catalysis; Circular Dichroism; Fungi; Glutamine; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Peptide Hydrolases; Proline; Protein Conformation; Serine Endopeptidases; Tryptophan | 2010 |
Prevalence of H63D, S65C, and C282Y hereditary hemochromatosis gene variants in Madeira Island (Portugal).
Topics: Adolescent; Adult; Amino Acid Substitution; Aspartic Acid; Cysteine; Gene Frequency; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Male; Membrane Proteins; Polymorphism, Single Nucleotide; Portugal; Prevalence; Serine; Tyrosine; Young Adult | 2011 |
Structural and kinetic analysis of Bacillus subtilis N-acetylglucosaminidase reveals a unique Asp-His dyad mechanism.
Topics: Acetylglucosamine; Acetylglucosaminidase; Amino Acid Sequence; Aspartic Acid; Bacillus subtilis; Bacterial Proteins; Binding Sites; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutation; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sodium Azide; Substrate Specificity | 2010 |
Residues R282 and D341 act as electrostatic gates in the proton-dependent oligopeptide transporter PepT1.
Topics: Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Cell Membrane; Dipeptides; Electrophysiological Phenomena; Female; Histidine; Hydrogen-Ion Concentration; Ion Channel Gating; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Peptide Transporter 1; Protons; Rabbits; RNA, Complementary; Static Electricity; Symporters; Xenopus laevis | 2011 |
Mass spectrometry detection of histidine phosphorylation on NM23-H1.
Topics: Amino Acid Sequence; Aspartic Acid; Chromatography, Liquid; Histidine; Humans; Hydrogen-Ion Concentration; Molecular Sequence Data; NM23 Nucleoside Diphosphate Kinases; Phosphorylation; Proteomics; Recombinant Proteins; Tandem Mass Spectrometry | 2011 |
Enhancement of laccase activity through the construction and breakdown of a hydrogen bond at the type I copper center in Escherichia coli CueO and the deletion mutant Δα5-7 CueO.
Topics: Amino Acid Sequence; Aspartic Acid; Copper; Electron Transport; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Histidine; Hydrogen Bonding; Laccase; Molecular Sequence Data; Oxidation-Reduction; Oxidoreductases; Proline; Sequence Deletion; Substrate Specificity; Thermodynamics | 2011 |
A comparison study between polymeric ligand and monomeric ligand for oligopeptide adsorption.
Topics: Adsorption; Aspartic Acid; Calorimetry, Differential Scanning; Histidine; Leucine; Ligands; Models, Molecular; Oligopeptides; Polymers; Sepharose | 2011 |
D216H polymorphism within TOR1A does not affect penetrance in DRD and is not a general modifier in primary dystonia.
Topics: Aspartic Acid; Dystonic Disorders; Family Health; Female; Gene Frequency; Histidine; Humans; Male; Molecular Chaperones; Penetrance; Polymorphism, Genetic | 2011 |
His75-Asp97 cluster in green proteorhodopsin.
Topics: Aspartic Acid; Color; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Reference Standards; Rhodopsin; Rhodopsins, Microbial | 2011 |
Proton-coupled electron transfer in the catalytic cycle of Alcaligenes xylosoxidans copper-dependent nitrite reductase.
Topics: Alcaligenes; Amino Acid Substitution; Asparagine; Aspartic Acid; Catalytic Domain; Copper; Crystallography, X-Ray; Electron Transport; Histidine; Nitrite Reductases; Protons; Recombinant Proteins | 2011 |
Evidence of the participation of remote residues in the catalytic activity of Co-type nitrile hydratase from Pseudomonas putida.
Topics: Aspartic Acid; Binding Sites; Catalysis; Glutamic Acid; Histidine; Hydro-Lyases; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Pseudomonas putida | 2011 |
A QM/QM investigation of the hUNG2 reaction surface: the untold tale of a catalytic residue.
Topics: Asparagine; Aspartic Acid; Catalysis; Catalytic Domain; Computer Simulation; DNA Mutational Analysis; Glutamic Acid; Histidine; Humans; Models, Molecular; Proline; Protons; Quantum Theory; Static Electricity; Surface Properties; Uracil-DNA Glycosidase; Water | 2011 |
First-principles molecular dynamics study on the atomistic behavior of His503 in bovine cytochrome c oxidase.
Topics: Animals; Aspartic Acid; Binding Sites; Cattle; Crystallography, X-Ray; Electron Transport Complex IV; Histidine; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Oxidation-Reduction; Oxygen; Protein Structure, Tertiary; Protons; Thermodynamics | 2011 |
The structural feature surrounding glycated lysine residues in human hemoglobin.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Chromatography, High Pressure Liquid; Glyceraldehyde; Glycosylation; Hemoglobins; Histidine; Humans; Lysine; Models, Molecular; Peptides; Protein Stability; Protein Structure, Secondary; Sequence Analysis, Protein | 2011 |
Ligation of D1-His332 and D1-Asp170 to the manganese cluster of photosystem II from Synechocystis assessed by multifrequency pulse EPR spectroscopy.
Topics: Aspartic Acid; Electron Spin Resonance Spectroscopy; Histidine; Manganese; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oxygen; Photosystem II Protein Complex; Protein Conformation; Synechocystis | 2011 |
Structural insights into the activation and inhibition of histo-aspartic protease from Plasmodium falciparum.
Topics: Animals; Aspartic Acid; Aspartic Acid Proteases; Catalytic Domain; Crystallization; Crystallography, X-Ray; Escherichia coli; Histidine; Humans; Molecular Conformation; Plasmodium falciparum; Protein Folding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Swine | 2011 |
Functional consequences of the creation of an Asp-His-Fe triad in a 3/3 globin.
Topics: Animals; Aspartic Acid; Catalytic Domain; Crystallography, X-Ray; Electrochemistry; Globins; Helminth Proteins; Histidine; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Polychaeta; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman | 2011 |
Aspartate 112 is the selectivity filter of the human voltage-gated proton channel.
Topics: Aspartic Acid; Electric Conductivity; Histidine; Humans; Ion Channel Gating; Ion Channels; Isotonic Solutions; Lysine; Mutant Proteins; Mutation; Open Reading Frames; Osmolar Concentration; Permeability; Protons; Substrate Specificity; Sucrose | 2011 |
A de novo peptide hexamer with a mutable channel.
Topics: Aspartic Acid; Crystallography, X-Ray; Histidine; Models, Molecular; Oligopeptides; Protein Conformation; Protein Engineering; Synthetic Biology | 2011 |
Conserved water-mediated H-bonding dynamics of catalytic His159 and Asp158: insight into a possible acid-base coupled mechanism in plant thiol protease.
Topics: Amino Acid Motifs; Aspartic Acid; Biocatalysis; Catalytic Domain; Cysteine Proteases; Histidine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Plant Proteins; Protein Binding; Thermodynamics; Water | 2012 |
Characterization of the BaeSR two-component system from Salmonella Typhimurium and its role in ciprofloxacin-induced mdtA expression.
Topics: Anti-Bacterial Agents; Aspartic Acid; Ciprofloxacin; Cloning, Molecular; Gene Expression Regulation, Bacterial; Histidine; Histidine Kinase; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Kinases; Salmonella typhimurium; Trans-Activators | 2012 |
Triazacyclophane (TAC)-scaffolded histidine and aspartic acid residues as mimics of non-heme metalloenzyme active sites.
Topics: Aspartic Acid; Aza Compounds; Biomimetic Materials; Catalytic Domain; Coordination Complexes; Copper; Heterocyclic Compounds, 2-Ring; Histidine; Metalloproteins; Oxygen | 2012 |
A proximal pair of positive charges provides the dominant ligand-binding contribution to complement-like domains from the LRP (low-density lipoprotein receptor-related protein).
Topics: Alanine; Amino Acid Motifs; Arginine; Aspartic Acid; Binding Sites; Histidine; Humans; Hydrogen-Ion Concentration; LDL-Receptor Related Proteins; Lysine; Models, Molecular; Peptide Fragments; Protein Structure, Tertiary; Recombinant Proteins; Spectrometry, Fluorescence; Thermodynamics | 2012 |
The prognostic role of hemochromatosis H63D allele in allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Alleles; Amino Acid Substitution; Aspartic Acid; Female; Hematopoietic Stem Cell Transplantation; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; Humans; Iron Overload; Male; Membrane Proteins; Middle Aged; Prognosis; Transplantation, Homologous; Treatment Outcome; Young Adult | 2012 |
Identification of multicomponent histidine-aspartate phosphorelay system controlling flagellar and motility gene expression in Geobacter species.
Topics: Aspartic Acid; Flagella; Gene Expression Regulation, Bacterial; Geobacter; Histidine; Histidine Kinase; Phosphorylation; Protein Kinases | 2012 |
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response.
Topics: Adaptor Proteins, Signal Transducing; Amidohydrolases; Amino Acid Sequence; Animals; Aspartic Acid; B-Cell CLL-Lymphoma 10 Protein; Biocatalysis; Caspases; Catalytic Domain; Crystallography, X-Ray; Cysteine; Diglycerides; DNA Mutational Analysis; Dysentery, Bacillary; Glutamic Acid; Glutamine; HEK293 Cells; HeLa Cells; Histidine; Humans; Immunity, Innate; Inflammation; Mice; Models, Molecular; Molecular Sequence Data; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Neoplasm Proteins; NF-kappa B; Shigella flexneri; TNF Receptor-Associated Factor 6; Ubiquitin-Conjugating Enzymes; Virulence Factors | 2012 |
Spin delocalization over type zero copper.
Topics: Aspartic Acid; Azurin; Copper; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Electrons; Escherichia coli; Histidine; Leucine; Ligands; Magnetic Resonance Spectroscopy; Methionine; Models, Molecular; Mutation; Oxidation-Reduction; Pseudomonas aeruginosa; Recombinant Proteins | 2012 |
Amyloid-beta (Aβ) D7H mutation increases oligomeric Aβ42 and alters properties of Aβ-zinc/copper assemblies.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Aspartic Acid; Base Sequence; Cells, Cultured; Copper; Female; HEK293 Cells; Histidine; Humans; Middle Aged; Molecular Sequence Data; Mutation; Peptide Fragments; Polymerization; Taiwan; Zinc | 2012 |
Inhibition of mushroom tyrosinase by a newly synthesized ligand: inhibition kinetics and computational simulations.
Topics: Agaricales; Aspartic Acid; Catalytic Domain; Catechol Oxidase; Copper; Enzyme Inhibitors; Histidine; Hydrazones; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Kinetics; Ligands; Molecular Dynamics Simulation; Monophenol Monooxygenase; Nitrobenzenes; Protein Binding; Spectrometry, Fluorescence | 2012 |
Aspartate-histidine interaction in the retinal schiff base counterion of the light-driven proton pump of Exiguobacterium sibiricum.
Topics: Aspartic Acid; Bacillales; Bacterial Proteins; Cloning, Molecular; Escherichia coli; Histidine; Kinetics; Models, Molecular; Mutation; Photochemical Processes; Protons; Rhodopsins, Microbial; Schiff Bases; Spectrometry, Fluorescence | 2012 |
The role of amino acid residues in the active site of L-methionine γ-lyase from Pseudomonas putida.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Carbon-Sulfur Lyases; Catalytic Domain; Cysteine; Dimerization; Histidine; Hydrogen Bonding; Kinetics; Lysine; Methionine; Models, Molecular; Protein Structure, Secondary; Protein Subunits; Pseudomonas putida; Recombinant Proteins; Substrate Specificity | 2012 |
Extracellular pH regulates zinc signaling via an Asp residue of the zinc-sensing receptor (ZnR/GPR39).
Topics: Aspartic Acid; Binding Sites; Biological Transport; Calcium; Cell Line, Tumor; Colon; HEK293 Cells; Histidine; Humans; Hydrogen-Ion Concentration; Ions; Mutation; Receptors, G-Protein-Coupled; Signal Transduction; Zinc | 2012 |
Chemical modification of catalytic site of lipase from wheat germ: altered structure-activity profile.
Topics: Aspartic Acid; Calorimetry, Differential Scanning; Catalytic Domain; Circular Dichroism; Dose-Response Relationship, Drug; Histidine; Hot Temperature; Kinetics; Lipase; Protein Conformation; Protein Structure, Secondary; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Temperature; Triticum | 2002 |
Cloning, high-level expression and enzymatic properties of an intracellular serine protease from Bacillus sp. WRD-2.
Topics: Amino Acid Sequence; Aspartic Acid; Bacillus; Bacterial Proteins; Biochemistry; Cloning, Molecular; Cytoplasm; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Histidine; Hydrogen-Ion Concentration; Molecular Sequence Data; Plasmids; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Serine Proteases; Temperature | 2004 |
Contrasting effects of mutating active site residues, aspartic acid 64 and histidine 187 of Escherichia coli uracil-DNA glycosylase on uracil excision and interaction with an inhibitor protein.
Topics: Aspartic Acid; Catalysis; Catalytic Domain; Crystallography, X-Ray; DNA; Enzyme Inhibitors; Escherichia coli; Histidine; Models, Genetic; Mutation; Oligonucleotides; Protein Binding; Sequence Analysis, DNA; Uracil; Uracil-DNA Glycosidase | 2002 |
Multiple sensor array of Mn2+, Fe2+, Co2+, Ni2+, Cu2+, and Zn2+ complexes of a triazole linked imino-phenol based calix[4]arene conjugate for the selective recognition of Asp, Glu, Cys, and His.
Topics: Aspartic Acid; Calixarenes; Cysteine; Glutamic Acid; Histidine; Imines; Models, Molecular; Molecular Structure; Organometallic Compounds; Phenols; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Transition Elements; Triazoles | 2012 |
A single residue change leads to a hydroxylated product from the class II diterpene cyclization catalyzed by abietadiene synthase.
Topics: Abies; Aspartic Acid; Catalysis; Cyclization; Diterpenes; Histidine; Hydroxylation; Isomerases; Molecular Structure; Organophosphates; Polyisoprenyl Phosphates | 2012 |
VPS35 Asp620Asn and EIF4G1 Arg1205His mutations are rare in Parkinson disease from southwest China.
Topics: Adult; Aged; Arginine; Asparagine; Aspartic Acid; Case-Control Studies; China; Eukaryotic Initiation Factor-4G; Female; Histidine; Humans; Male; Middle Aged; Mutation; Parkinson Disease; Vesicular Transport Proteins; Young Adult | 2013 |
Signal transduction and phosphoryl transfer by a FixL hybrid kinase with low oxygen affinity: importance of the vicinal PAS domain and receiver aspartate.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Heme; Hemeproteins; Histidine; Histidine Kinase; Kinetics; Ligands; Mutant Proteins; Oxidation-Reduction; Oxygen; Peptide Fragments; Phosphorylation; Protein Binding; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Recombinant Proteins; Rhizobium; Signal Transduction | 2013 |
Salt bridge in the conserved His-Asp cluster in Gloeobacter rhodopsin contributes to trimer formation.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Bacteriorhodopsins; Chromatography, Gel; Circular Dichroism; Conserved Sequence; Cyanobacteria; Detergents; Glucosides; Histidine; Hydrogen-Ion Concentration; Models, Molecular; Mutant Proteins; Protein Structure, Quaternary; Recombinant Proteins; Schiff Bases | 2013 |
Proteome-wide analysis of nonsynonymous single-nucleotide variations in active sites of human proteins.
Topics: Abnormalities, Multiple; Amino Acid Substitution; Arginine; Aspartic Acid; Carbohydrate Metabolism; Catalytic Domain; Cluster Analysis; Enzyme Activation; Genetic Variation; Genome, Human; Glycogen Storage Disease; Hearing Loss; Histidine; Humans; Lacrimal Apparatus Diseases; Metabolomics; Molecular Sequence Annotation; Phenylalanine; Polymorphism, Single Nucleotide; Proteome; Proteomics; Structure-Activity Relationship; Syndactyly; Tooth Abnormalities; Tyrosine | 2013 |
Analysis of D216H polymorphism in Argentinean patients with primary dystonia.
Topics: Adolescent; Adult; Age of Onset; Argentina; Aspartic Acid; Child; Dystonic Disorders; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Histidine; Humans; Male; Middle Aged; Molecular Chaperones; Polymorphism, Single Nucleotide; Young Adult | 2013 |
Hypodysfibrinogenaemia and thrombosis in association with a new fibrinogen γ chain with two mutations (γ114Tyr→His, and γ320Asp deleted).
Topics: Afibrinogenemia; Aspartic Acid; Binding Sites; Chromatography, High Pressure Liquid; Dimerization; Fibrinogen; Gene Deletion; Genetic Variation; Histidine; Humans; Infant; Male; Mutation; Phenotype; Sequence Analysis, DNA; Thrombosis; Tyrosine | 2013 |
Intermittent and continuous imatinib in a human GIST xenograft model carrying KIT exon 17 resistance mutation D816H.
Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Aspartic Acid; Benzamides; Drug Administration Schedule; Drug Resistance, Neoplasm; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Histidine; Humans; Imatinib Mesylate; Mice; Mice, Nude; Mutation, Missense; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Xenograft Model Antitumor Assays | 2013 |
No increase in bleeding identified in type 1 VWD subjects with D1472H sequence variation.
Topics: Amino Acid Substitution; Aspartic Acid; Case-Control Studies; Hemorrhage; Histidine; Humans; Incidence; Mutation, Missense; Research Design; Severity of Illness Index; von Willebrand Disease, Type 1; von Willebrand Factor | 2013 |
Copper(II) coordination properties of decapeptides containing three His residues: the impact of cyclization and Asp residue coordination.
Topics: Aspartic Acid; Circular Dichroism; Coordination Complexes; Copper; Cyclization; Histidine; Kinetics; Oligopeptides; Protons; Spectrophotometry, Ultraviolet | 2013 |
Photocycle and vectorial proton transfer in a rhodopsin from the eukaryote Oxyrrhis marina.
Topics: Aquatic Organisms; Aspartic Acid; Dinoflagellida; Histidine; Hydrogen-Ion Concentration; Light; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Photochemistry; Protons; Rhodopsin; Schiff Bases | 2013 |
A histidine aspartate ionic lock gates the iron passage in miniferritins from Mycobacterium smegmatis.
Topics: Aspartic Acid; Bacterial Proteins; Biological Transport, Active; Crystallography, X-Ray; Ferritins; Histidine; Iron; Mycobacterium smegmatis; Protein Structure, Tertiary; Structure-Activity Relationship | 2014 |
Evaluating the strength of salt bridges: a comparison of current biomolecular force fields.
Topics: Amino Acids; Arginine; Aspartic Acid; Dipeptides; Histidine; Lysine; Molecular Dynamics Simulation; Salts; Solvents; Water | 2014 |
Molecular basis of the general base catalysis of an α/β-hydrolase catalytic triad.
Topics: Aspartic Acid; Catalysis; Crystallography, X-Ray; Enzyme Activation; Escherichia coli; Histidine; Hydrogen Bonding; Mutagenesis, Site-Directed; Oxo-Acid-Lyases; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Structure-Activity Relationship; Vitamin K | 2014 |
New force field parameters for metalloproteins I: Divalent copper ion centers including three histidine residues and an oxygen-ligated amino acid residue.
Topics: Aspartic Acid; Copper; Glutamic Acid; Histidine; Metalloproteins; Models, Molecular; Molecular Dynamics Simulation; Thermodynamics; Tyrosine | 2014 |
His224 alters the R2 drug binding site and Phe218 influences the catalytic efficiency of the metallo-β-lactamase VIM-7.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Aspartic Acid; beta-Lactam Resistance; beta-Lactamases; Binding Sites; Biocatalysis; Cefepime; Ceftazidime; Cephalosporins; Endopeptidases; Enzyme Stability; Escherichia coli; Gene Expression; Histidine; Hot Temperature; Hydrogen Bonding; Molecular Docking Simulation; Phenylalanine; Protein Binding; Pseudomonas aeruginosa; Recombinant Fusion Proteins; Static Electricity; Structure-Activity Relationship | 2014 |
Mechanism of action of peptidoglycan O-acetyltransferase B involves a Ser-His-Asp catalytic triad.
Topics: Acyltransferases; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Biocatalysis; Chromatography, Liquid; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Histidine; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Models, Molecular; Mutation, Missense; Neisseria gonorrhoeae; Oligopeptides; Peptidoglycan; Polysaccharides, Bacterial; Protein Binding; Protein Structure, Tertiary; Serine; Substrate Specificity | 2014 |
Ribosome-induced tuning of GTP hydrolysis by a translational GTPase.
Topics: Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Codon; GTP Phosphohydrolases; Guanosine Triphosphate; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Models, Molecular; Molecular Conformation; Molecular Structure; Mutation; Peptide Elongation Factor Tu; Protein Binding; Protein Biosynthesis; Ribosomes; RNA, Transfer, Amino Acyl | 2014 |
Evidence of histidine and aspartic acid phosphorylation in human prostate cancer cells.
Topics: Aspartic Acid; Cell Line; Cell Line, Tumor; Histidine; Humans; Male; NM23 Nucleoside Diphosphate Kinases; Phosphorylation; Prostatic Neoplasms; Proteomics | 2015 |
Characterization of Avt1p as a vacuolar proton/amino acid antiporter in Saccharomyces cerevisiae.
Topics: Amino Acid Transport Systems; Amino Acids, Neutral; Antiporters; Aspartic Acid; Biological Transport; gamma-Aminobutyric Acid; Glutamic Acid; Histidine; Intracellular Membranes; Isoleucine; Protons; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Vacuoles | 2015 |
Remote His50 Acts as a Coordination Switch in the High-Affinity N-Terminal Centered Copper(II) Site of α-Synuclein.
Topics: alpha-Synuclein; Aspartic Acid; Binding Sites; Copper; Electron Spin Resonance Spectroscopy; Histidine; Humans; Hydrogen-Ion Concentration; Models, Molecular; Peptides; Protein Aggregates; Protein Binding; Protein Folding; Solid-Phase Synthesis Techniques | 2015 |
Functional Characterization of the Receiver Domain for Phosphorelay Control in Hybrid Sensor Kinases.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Binding Sites; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Histidine; Histidine Kinase; Membrane Proteins; Phosphorylation; Phosphotransferases; Protein Kinases; Signal Transduction | 2015 |
Mechanism of NH4(+) Recruitment and NH3 Transport in Rh Proteins.
Topics: Ammonia; Aspartic Acid; Cation Transport Proteins; Cell Membrane; Dimyristoylphosphatidylcholine; Histidine; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Ion Transport; Kinetics; Membrane Glycoproteins; Molecular Dynamics Simulation; Protein Multimerization; Protons; Quantum Theory; Static Electricity; Thermodynamics | 2015 |
Glassin, a histidine-rich protein from the siliceous skeletal system of the marine sponge Euplectella, directs silica polycondensation.
Topics: Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Binding Sites; Cloning, Molecular; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Epitopes; Geography; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Molecular Sequence Data; Peptides; Porifera; Proline; Protein Processing, Post-Translational; Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Silicon Dioxide; Solubility; Temperature; Threonine | 2015 |
Structural Insights into the High-efficiency Catalytic Mechanism of the Sterile α-Motif/Histidine-Aspartate Domain-containing Protein.
Topics: Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalysis; Cell Cycle; Crystallography, X-Ray; Escherichia coli; Guanosine Triphosphate; Histidine; Humans; Hydrolysis; Immunity, Innate; Macrophages; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Mutagenesis, Site-Directed; Plasmids; Protein Multimerization; Protein Structure, Tertiary; Recombinant Proteins; SAM Domain and HD Domain-Containing Protein 1; Sequence Homology, Amino Acid | 2015 |
Hemoglobin A2-Leuven (α2δ2 143(H21) His>Asp): a novel delta-chain variant potentially interfering in hemoglobin A1c measurement using cation exchange HPLC.
Topics: Adult; Aspartic Acid; Cations; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Diabetes Mellitus, Type 2; Female; Genetic Variation; Glycated Hemoglobin; Hematologic Tests; Hemoglobin A2; Histidine; Humans | 2016 |
Impact of pnpR, a LysR-type regulator-encoding gene, on the cellular processes of Pseudomonas putida DLL-E4.
Topics: Aspartic Acid; Bacterial Proteins; Catabolite Repression; Computational Biology; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genes, Regulator; Histidine; Lactic Acid; Nitrophenols; Operon; Pseudomonas putida; Serine; Transcriptional Activation | 2016 |
Enhancing the Activity of Peptide-Based Artificial Hydrolase with Catalytic Ser/His/Asp Triad and Molecular Imprinting.
Topics: Amino Acid Sequence; Aspartic Acid; Catalysis; Histidine; Hydrolases; Models, Molecular; Molecular Imprinting; Peptides; Serine | 2016 |
Structural characterization of the heme-based oxygen sensor, AfGcHK, its interactions with the cognate response regulator, and their combined mechanism of action in a bacterial two-component signaling system.
Topics: Aeromonas salmonicida; Aspartic Acid; Bacterial Proteins; Cloning, Molecular; Deuterium Exchange Measurement; Escherichia coli; Heme; Histidine; Histidine Kinase; Iron; Myxococcales; Oxygen; Phosphorylation; Protein Domains; Protein Structure, Secondary; Recombinant Proteins; Signal Transduction; Structural Homology, Protein | 2016 |
Pre-formulation and systematic evaluation of amino acid assisted permeability of insulin across in vitro buccal cell layers.
Topics: Aspartic Acid; Cell Line, Tumor; Cell Membrane; Cell Membrane Permeability; Cell Survival; Deoxycholic Acid; Electric Impedance; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Insulin; Kinetics; Lysine; Mouth Mucosa | 2016 |
Structural basis of haem-iron acquisition by fungal pathogens.
Topics: Aspartic Acid; Biological Transport; Candida albicans; Crystallography, X-Ray; Cysteine; Fungal Proteins; Heme; Hemeproteins; Histidine; Iron; Membrane Proteins; Molecular Conformation | 2016 |
An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis.
Topics: Adenine; Aspartic Acid; Bacillus megaterium; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Histidine; Kinetics; Phosphoric Monoester Hydrolases; Protein Conformation; Signal Transduction; Substrate Specificity | 2016 |
Strong Impact of an Axial Ligand on the Absorption by Chlorophyll a and b Pigments Determined by Gas-Phase Ion Spectroscopy Experiments.
Topics: Acetylcholine; Aspartic Acid; Chlorophyll; Chlorophyll A; Energy Transfer; Formates; Glutamic Acid; Histidine; Kinetics; Ligands; Magnesium; Models, Molecular; Photosystem II Protein Complex; Pisum sativum; Protein Structure, Secondary; Spectrum Analysis; Static Electricity; Thermodynamics | 2016 |
Lens metabolomic profiling as a tool to understand cataractogenesis in Atlantic salmon and rainbow trout reared at optimum and high temperature.
Topics: Amino Acids; Animals; Aspartic Acid; Carbohydrate Metabolism; Cataract; Fish Diseases; Glutathione; Histidine; Homeostasis; Hot Temperature; Lens, Crystalline; Metabolomics; Oncorhynchus mykiss; Osmoregulation; Oxidation-Reduction; Salmo salar; Seawater; Severity of Illness Index; Species Specificity; Temperature | 2017 |
Heme Proximal Hydrogen Bonding between His170 and Asp132 Plays an Essential Role in the Heme Degradation Reaction of HutZ from Vibrio cholerae.
Topics: Aspartic Acid; Bacterial Proteins; Heme; Histidine; Hydrogen Bonding; Molecular Structure; Vibrio cholerae | 2017 |
Theoretical insights into the protonation states of active site cysteine and citrullination mechanism of Porphyromonas gingivalis peptidylarginine deiminase.
Topics: Amino Acid Motifs; Arginine; Aspartic Acid; Bacterial Proteins; Binding Sites; Catalytic Domain; Citrulline; Crystallography, X-Ray; Cysteine; Histidine; Hydrolases; Hydrolysis; Molecular Dynamics Simulation; Porphyromonas gingivalis; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein-Arginine Deiminases; Protons; Quantum Theory; Substrate Specificity; Thermodynamics | 2017 |
Site-specific His/Asp phosphoproteomic analysis of prokaryotes reveals putative targets for drug resistance.
Topics: Acinetobacter baumannii; Amino Acids; Aspartic Acid; Bacteria; Bacterial Proteins; Binding Sites; Drug Resistance; Helicobacter pylori; Histidine; Klebsiella pneumoniae; Phosphorylation; Prokaryotic Cells; Protein Processing, Post-Translational; Proteomics; Sequence Analysis, Protein; Vibrio vulnificus; Zinc | 2017 |
Mapping the 'Two-component system' network in rice.
Topics: Aspartic Acid; Biomarkers; Fluorescent Antibody Technique; Gene Expression Regulation, Plant; Histidine; Models, Biological; Oryza; Plant Proteins; Protein Interaction Mapping; Signal Transduction; Two-Hybrid System Techniques | 2017 |
Effects of three major amino acids found in Japanese broth on glucose metabolism and gastric emptying.
Topics: Adult; Amino Acids; Animals; Aspartic Acid; Blood Glucose; C-Peptide; Cross-Over Studies; Diet; Female; Fishes; Food, Preserved; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glutamic Acid; Histidine; Humans; Insulin; Japan; Kelp; Male; Oryza | 2018 |
Recognition dynamics of trinuclear copper cluster and associated histidine residues through conserved or semi-conserved water molecules in human Ceruloplasmin: The involvement of aspartic and glutamic acid gates.
Topics: Aspartic Acid; Ceruloplasmin; Copper; Glutamic Acid; Histidine; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Conformation; Oxidoreductases; Structure-Activity Relationship; Water | 2018 |
Effect of pH on Aβ
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Aspartic Acid; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Lysine; Molecular Dynamics Simulation; Peptide Fragments; Protein Aggregates; Protein Conformation, beta-Strand; Protein Folding; Protein Multimerization | 2018 |
Intra-electron transfer induced by protonation in copper-containing nitrite reductase.
Topics: Aspartic Acid; Catalytic Domain; Copper; Crystallography, X-Ray; Cysteine; Electrons; Histidine; Kinetics; Nitrite Reductases; Nitrites; Oxidation-Reduction; Protein Conformation; Protons | 2018 |
Influence of Aspartate Moieties on the Self-Healing Behavior of Histidine-Rich Supramolecular Polymers.
Topics: Aspartic Acid; Cross-Linking Reagents; Histidine; Macromolecular Substances; Molecular Structure; Polymers; Zinc Acetate | 2018 |
D409H GBA1 mutation accelerates the progression of pathology in A53T α-synuclein transgenic mouse model.
Topics: alpha-Synuclein; Animals; Aspartic Acid; Brain Stem; Disease Progression; Endoplasmic Reticulum Stress; Gaucher Disease; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glucosylceramidase; Histidine; Humans; Longevity; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Tyrosine 3-Monooxygenase | 2018 |
QM/MM Studies of Dph5 - A Promiscuous Methyltransferase in the Eukaryotic Biosynthetic Pathway of Diphthamide.
Topics: Aspartic Acid; Biosynthetic Pathways; Computer Simulation; Histidine; Methylation; Methyltransferases; Molecular Docking Simulation; Molecular Dynamics Simulation; Peptide Elongation Factor 2; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; Saccharomyces cerevisiae Proteins; Static Electricity | 2018 |
Routes of phosphoryl group transfer during signal transmission and signal decay in the dimeric sensor histidine kinase ArcB.
Topics: Aspartic Acid; Escherichia coli; Escherichia coli Proteins; Histidine; Membrane Proteins; Mutation; Phosphorylation; Protein Kinases; Signal Transduction | 2018 |
Direct evidence of a low barrier hydrogen bond in the catalytic triad of a Serine protease.
Topics: Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Dengue; Dengue Virus; Histidine; Humans; Hydrogen Bonding; Serine; Serine Proteases | 2018 |
Histone Tail Sequences Balance Their Role in Genetic Regulation and the Need To Protect DNA against Destruction in Nucleosome Core Particles Containing Abasic Sites.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; DNA; DNA Cleavage; Glutamic Acid; Histidine; Histones; Humans; Lysine; Mice; Mutation; Nucleosomes; Saccharomyces cerevisiae; Xenopus laevis | 2019 |
Progress of Brain Amyloid Deposition in Familial Alzheimer's Disease with Taiwan D678H APP Mutation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Aniline Compounds; Aspartic Acid; Brain; Cognitive Dysfunction; Disease Progression; Ethylene Glycols; Family Health; Female; Follow-Up Studies; Histidine; Humans; Male; Middle Aged; Positron-Emission Tomography; Taiwan | 2018 |
Protein Arginine Deiminases (PADs): Biochemistry and Chemical Biology of Protein Citrullination.
Topics: Animals; Aspartic Acid; Catalysis; Catalytic Domain; Citrullination; Cysteine; Enzyme Inhibitors; HEK293 Cells; Histidine; Humans; Mice; Models, Chemical; Mutation; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Proteins | 2019 |
Stable Lanthanide-Organic Framework as a Luminescent Probe To Detect Both Histidine and Aspartic Acid in Water.
Topics: Aspartic Acid; Europium; Histidine; Lanthanoid Series Elements; Luminescence; Luminescent Agents; Luminescent Measurements; Metal-Organic Frameworks; Models, Molecular; Tricarboxylic Acids; Water | 2019 |
Amino acid signature predictive of incident prediabetes: A case-control study nested within the longitudinal pathobiology of prediabetes in a biracial cohort.
Topics: Adult; Amino Acids; Asparagine; Aspartic Acid; Black or African American; Blood Glucose; Case-Control Studies; Cohort Studies; Female; Follow-Up Studies; Histidine; Humans; Insulin Resistance; Insulin-Secreting Cells; Longitudinal Studies; Male; Middle Aged; Prediabetic State; Predictive Value of Tests; Racial Groups; White People | 2019 |
QM/MM Study of the Uracil DNA Glycosylase Reaction Mechanism: A Competition between Asp145 and His148.
Topics: Aspartic Acid; Histidine; Humans; Models, Molecular; Protons; Quantum Theory; Thermodynamics; Uracil-DNA Glycosidase; Water | 2019 |
Artificial β-propeller protein-based hydrolases.
Topics: Amino Acid Sequence; Aspartic Acid; Butyrates; Catalysis; Copper; Histidine; Hydrolases; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Nitrophenols; Protein Engineering; Protein Structure, Tertiary; Threonine; Zinc | 2019 |
Quantitative monitoring of His and Asp phosphorylation in a bacterial signaling system by using Phos-tag Magenta/Cyan fluorescent dyes.
Topics: Aspartic Acid; Bacterial Outer Membrane Proteins; Bacterial Proteins; Escherichia coli Proteins; Fluorescent Dyes; Histidine; Multienzyme Complexes; Phosphoproteins; Phosphorylation; Signal Transduction; Trans-Activators | 2019 |
Amyloid beta oligomers: how pH influences over trimer and pentamer structures?
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Aspartic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Dynamics Simulation; Peptide Fragments; Protein Aggregation, Pathological; Protein Conformation; Protein Multimerization | 2019 |
A mutation in CsHD encoding a histidine and aspartic acid domain-containing protein leads to yellow young leaf-1 (yyl-1) in cucumber (Cucumis sativus L.).
Topics: Aspartic Acid; Chlorophyll; Chloroplasts; Chromosome Mapping; Cloning, Molecular; Color; Cucumis sativus; DNA, Plant; Exons; Gene Expression Regulation, Plant; Genes, Plant; Genes, Recessive; Histidine; Mutation; Nicotiana; Phenotype; Plant Leaves; Plant Proteins; Protein Domains | 2020 |
pH-Sensitive Mechanical Properties of Elastin-Based Hydrogels.
Topics: Acetylation; Amino Acid Sequence; Aspartic Acid; Biocompatible Materials; Drug Delivery Systems; Elastin; Escherichia coli; Gene Expression; Histidine; Humans; Hydrogels; Hydrogen-Ion Concentration; Lab-On-A-Chip Devices; Lysine; Protein Engineering; Recombinant Proteins; Tissue Engineering; Tyrosine; Water; Wettability | 2020 |
Methods to Study the Structure and Catalytic Activity of cis-Splicing Inteins.
Topics: Aspartic Acid; Biocatalysis; Biochemistry; Carbon Isotopes; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Exteins; Gene Expression; Genetic Vectors; Histidine; Hydrogen-Ion Concentration; Inteins; Maltose-Binding Proteins; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Splicing; Recombinant Fusion Proteins | 2020 |
Phos-Tag Fluorescent Gel Staining for the Quantitative Detection of His- and Asp-Phosphorylated Proteins.
Topics: Aspartic Acid; Bacterial Outer Membrane Proteins; Bacterial Proteins; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Fluorescent Dyes; Histidine; Multienzyme Complexes; Phosphoproteins; Phosphorylation; Proteomics; Pyridines; Trans-Activators | 2021 |
Charge Interactions in a Highly Charge-Depleted Protein.
Topics: Aspartic Acid; Cellulase; Cellulomonas; Histidine; Molecular Dynamics Simulation; Mutation; Protein Conformation; Protein Domains; Protein Unfolding; Static Electricity; Thermodynamics | 2021 |
Multiple oxidative and advanced oxidative modifications of hemoglobin in gastric cancer patients measured by nanoflow LC-MS/MS.
Topics: Aspartic Acid; Biomarkers; Chromatography, Liquid; Hemoglobins; Histidine; Humans; Oxidative Stress; Peptides; Stomach Neoplasms; Tandem Mass Spectrometry; Tyrosine | 2022 |
Electrostatic fingerprints of catalytically active amino acids in enzymes.
Topics: Amino Acids; Aspartic Acid; Glutamates; Histidine; Lysine; Static Electricity | 2022 |
Sterile alpha motif and histidine-aspartic acid domain-containing protein 1 expression and its relationship with T cell activation in human immunodeficiency virus/acquired immune deficiency syndrome patients with lung-spleen deficiency syndrome pattern.
Topics: Acquired Immunodeficiency Syndrome; Aspartic Acid; Histidine; HIV; HIV Infections; Humans; Lung; SAM Domain and HD Domain-Containing Protein 1; Spleen; Sterile Alpha Motif; T-Lymphocytes | 2022 |
The Role of Side Chains in the Fine-Tuning of the Metal-Binding Ability of Multihistidine Peptides.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Coordination Complexes; Copper; Histidine; Hydrogen-Ion Concentration; Peptides | 2022 |
Molecular determinants of pH sensing in the proton-activated chloride channel.
Topics: Aspartic Acid; Chloride Channels; Chlorides; Electrophysiological Phenomena; Histidine; Humans; Hydrogen-Ion Concentration; Mutagenesis; Protons | 2022 |
NMR-based metabolomic analysis for the effects of moxibustion on imiquimod-induced psoriatic mice.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Cytokines; Disease Models, Animal; Glucose; Histidine; Imiquimod; Interleukin-17; Interleukin-23; Interleukin-8; Magnetic Resonance Spectroscopy; Mice; Moxibustion; Psoriasis; Skin; Taurine; Triglycerides; Valine | 2023 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
[Determination of free amino acids in Eriocheir sinensis by ultra-high performance liquid chromatography-high resolution mass spectrometry].
Topics: Acetonitriles; Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brachyura; Chromatography, High Pressure Liquid; Cystine; Formates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Mass Spectrometry; Methionine; Perchlorates; Phenylalanine; Polypropylenes; Proline; Serine; Solvents; Threonine; Tyrosine; Valine; Water | 2022 |
Intestinal metabolomics of juvenile lenok (Brachymystax lenok) in response to heat stress.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Acetylcarnitine; Animals; Aspartic Acid; Erucic Acids; Glucose; Glutamine; Heat-Shock Response; Histidine; Intestines; Lactates; Leucine; Methionine; Oxylipins; Palmitoylcarnitine; Phenylalanine; Phosphatidylcholines; Phosphorylcholine; Proline; Salmonidae; Tandem Mass Spectrometry; Tryptophan; Tyrosine | 2022 |
Association between CARD14 gene polymorphisms and psoriasis vulgaris in Hainan Han population based on exon sequencing: A case-control study.
Topics: Aspartic Acid; CARD Signaling Adaptor Proteins; Case-Control Studies; Exons; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Guanylate Cyclase; Histidine; Humans; Membrane Proteins; Polymorphism, Single Nucleotide; Psoriasis | 2022 |
Comparison of amino acid digestibility and its additivity determined with slaughter or cecectomy method for yellow-feather chicken.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Aspartic Acid; Chickens; Diet; Digestion; Feathers; Glutamic Acid; Glycine; Glycine max; Histidine; Ileum; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Valine; Zea mays | 2022 |
SPAD-1, a serine proteinase associated disintegrin from Russell's viper venom disrupts adhesion of MCF7 human breast cancer cells.
Topics: Animals; Aspartic Acid; Breast Neoplasms; Daboia; Disintegrins; Female; Fibronectins; Histidine; Humans; Laminin; MCF-7 Cells; Serine Proteases; Viper Venoms | 2023 |
Searching for Osmosensing Determinants in Poplar Histidine-Aspartate Kinases.
Topics: Arabidopsis; Aspartic Acid; Histidine; Histidine Kinase; Intracellular Signaling Peptides and Proteins; Populus; Protein Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2023 |
Deoxyguanosine-Linked Bifunctional Inhibitor of SAMHD1 dNTPase Activity and Nucleic Acid Binding.
Topics: Aspartic Acid; Deoxyguanosine; Guanosine Triphosphate; Histidine; Monomeric GTP-Binding Proteins; Nucleic Acids; SAM Domain and HD Domain-Containing Protein 1; Sterile Alpha Motif | 2023 |