Page last updated: 2024-08-17

histidine and alpha-synuclein

histidine has been researched along with alpha-synuclein in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (25.00)	29.6817
2010's	15 (62.50)	24.3611
2020's	3 (12.50)	2.80

Authors

Authors	Studies
Hachiya, NS; Jozuka, A; Kaneko, K; Sakasegawa, Y; Sasaki, H; Tsukita, S	1
Giasson, BI; Hodara, R; Ischiropoulos, H; Lee, VM; Norris, EH; Trojanowski, JQ; Xu, S	1
Andersen, PM; Collinge, J; Fisher, EM; Hardiman, O; Highley, R; Ince, PG; Morrison, KE; Pall, HS; Parkinson, N; Shaw, PJ; Skibinski, G; Smith, MO	1
Boyer, F; Dreyer, JL	1
Grzonka, Z; Jankowska, E; Kowalik-Jankowska, T; Rajewska, A	1
Brown, DR	1
Benfatto, M; Bisaglia, M; Bortolus, M; Bubacco, L; Fittipaldi, M; Maniero, AL; Zoleo, A	1
Baratto, MC; Camponeschi, F; Kozlowski, H; Luczkowski, M; Remelli, M; Valensin, D; Valensin, G	1
Barnes, CO; Monteith, WB; Pielak, GJ	1
Cobb, SA; Englund, E; Farrer, MJ; Kachergus, JM; Lincoln, SJ; Nilsson, C; Puschmann, A; Rehncrona, S; Ross, OA; Törnqvist, AL; Vilariño-Güell, C; Widner, H; Wszolek, ZK	1
Aasly, JO; Appel-Cresswell, S; Encarnacion, M; Farrer, MJ; Jon Stoessl, A; Rajput, A; Rajput, AH; Shah, B; Sherman, H; Szu-Tu, C; Thompson, C; Trinh, J; Vilarino-Guell, C; Weir, D; Yu, I	1
Armstrong, GS; Chi, YC; Eisenmesser, EZ; Jones, DN; Liu, CW	1
Binolfi, A; Fernández, CO; Griesinger, C; Miotto, MC; Zweckstetter, M	1
Cai, Z; Chen, LL; Chua, KK; Li, M; Liu, LF; Luan, H; Meng, N; Mok, VC; Song, JX; Tang, Z; Xie, LX	1
Becker, CM; Hoffmann, AC; Klucken, J; Meixner, H; Menges, S; Schlachetzki, JC; Schlötzer-Schrehardt, U; Winkler, J; Xiang, W	1
Casella, L; De Ricco, R; Dell'Acqua, S; Dorlet, P; Faller, P; Hureau, C; Valensin, D	1
Carlomagno, Y; DeTure, M; Dickson, DW; Hinkle, KM; Lin, WL; Pedraza, O; Rademakers, R; Ross, OA; Sanchez-Contreras, M; Tacik, P; Wszolek, ZK	1
Kumar, A; Ranjan, P	1
Abad Gonzalez, E; Carija, A; Carloni, P; Fernández, CO; Foguel, D; Fonseca-Ornelas, L; Gerhardt, E; Lopes da Fonseca, T; Masaracchia, C; Milosevic, I; Outeiro, TF; Pinho, R; Rossetti, G; Sant'Anna, R; Szegö, ÉM; Ventura, S; Villar-Piqué, A; Zweckstetter, M	1
Choi, S; Hwang, H; Kim, D; Kim, S; Ko, HS; Kwon, SH; Lee, S; Park, JH	1
Funayama, M; Hattori, N; Li, Y; Matsuura, E; Nishioka, K; Takanashi, M; Takashima, H; Tsuyama, S; Yoshino, H	1
Amininasab, M; Davoodi, J; Saffari, B; Sheikhi, S	1
Castañeda-Hernández, G; Fernández, CO; González, FJ; Quintanar, L; Ríos, A; Rodríguez, EE; Trujano-Ortiz, LG; Villegas, A	1
Chiu, YW; Hirayama, K; Hori, Y; Ikeda, T; Iwai, A; Iwata, A; Kanai, M; Mano, T; Nakamura, R; Sohma, Y; Suzuki, T; Tarutani, A; Toda, T; Tomita, T; Tomizawa, I	1

Other Studies

24 other study(ies) available for histidine and alpha-synuclein

Article	Year
Oligomeric Aip2p/Dld2p modifies the protein conformation of both properly folded and misfolded substrates in vitro. Biochemical and biophysical research communications, 2004, Oct-08, Volume: 323, Issue:1 Topics: Actins; Adenosine Triphosphate; alpha-Synuclein; Amyloid beta-Peptides; Cell Cycle; Chromatography, Gel; Deoxyribonuclease I; Histidine; Hydrolysis; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Molecular Chaperones; Nerve Tissue Proteins; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Surface Plasmon Resonance; Synucleins; Trypsin	2004
Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations. The Journal of biological chemistry, 2005, Jun-03, Volume: 280, Issue:22 Topics: alpha-Synuclein; Amino Acid Motifs; Circular Dichroism; DNA, Complementary; Dopamine; Histidine; Humans; Indolequinones; Methionine; Microscopy, Atomic Force; Microscopy, Electron; Mutagenesis; Mutation; Nerve Tissue Proteins; Oxidative Stress; Oxygen; Parkinson Disease; Peptides; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared; Synucleins; Time Factors; Tyrosine	2005
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B). Neurology, 2006, Sep-26, Volume: 67, Issue:6 Topics: Adaptor Proteins, Signal Transducing; Aged; alpha-Synuclein; Amyotrophic Lateral Sclerosis; Brain; DNA Mutational Analysis; Endosomal Sorting Complexes Required for Transport; Glial Fibrillary Acidic Protein; Glutamine; Histidine; Humans; Immunohistochemistry; Isoleucine; Male; Mutation; Nerve Tissue Proteins; Neurofilament Proteins; Phenotype; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequestosome-1 Protein; Spinal Cord; tau Proteins; Ubiquitin; Valine	2006
Alpha-synuclein in the nucleus accumbens induces changes in cocaine behaviour in rats. The European journal of neuroscience, 2007, Volume: 26, Issue:10 Topics: alpha-Synuclein; Analysis of Variance; Animals; Behavior, Animal; Cell Line, Transformed; Cocaine; Dopamine Uptake Inhibitors; Doxycycline; Histidine; Humans; Lentivirus; Locomotion; Nucleus Accumbens; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Self Administration; Time Factors; Transfection	2007
Products of Cu(II)-catalyzed oxidation of alpha-synuclein fragments containing M1-D2 and H50 residues in the presence of hydrogen peroxide. Dalton transactions (Cambridge, England : 2003), 2008, Feb-14, Issue:6 Topics: alpha-Synuclein; Amino Acid Sequence; Binding Sites; Catalysis; Cations, Divalent; Chromatography, High Pressure Liquid; Copper; Histidine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Lysine; Methionine; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfones	2008
Metal binding to alpha-synuclein peptides and its contribution to toxicity. Biochemical and biophysical research communications, 2009, Mar-06, Volume: 380, Issue:2 Topics: alpha-Synuclein; Amino Acid Sequence; Binding Sites; Cell Line, Tumor; Copper; Histidine; Humans; Iron; Molecular Sequence Data; Peptides; Protein Structure, Tertiary	2009
Structural characterization of a high affinity mononuclear site in the copper(II)-α-synuclein complex. Journal of the American Chemical Society, 2010, Dec-29, Volume: 132, Issue:51 Topics: alpha-Synuclein; Coordination Complexes; Copper; Electron Spin Resonance Spectroscopy; Histidine; Humans; Lewy Bodies; Metalloproteins; Protein Binding	2010
The role of His-50 of α-synuclein in binding Cu(II): pH dependence, speciation, thermodynamics and structure. Metallomics : integrated biometal science, 2011, Volume: 3, Issue:3 Topics: alpha-Synuclein; Amino Acid Sequence; Binding Sites; Circular Dichroism; Copper; Electron Spin Resonance Spectroscopy; Histidine; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Parkinson Disease; Thermodynamics	2011
Internal and global protein motion assessed with a fusion construct and in-cell NMR spectroscopy. Chembiochem : a European journal of chemical biology, 2011, Feb-11, Volume: 12, Issue:3 Topics: alpha-Synuclein; Histidine; Magnetic Resonance Spectroscopy; Oligopeptides; Protein Stability; Recombinant Fusion Proteins; Ubiquitin	2011
First neuropathological description of a patient with Parkinson's disease and LRRK2 p.N1437H mutation. Parkinsonism & related disorders, 2012, Volume: 18, Issue:4 Topics: Aged; alpha-Synuclein; Asparagine; Brain; DNA Mutational Analysis; DNA-Binding Proteins; Family Health; Female; Histidine; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Magnetic Resonance Imaging; Male; Parkinson Disease; Protein Serine-Threonine Kinases; RNA-Binding Protein FUS; Ubiquitin	2012
Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society, 2013, Volume: 28, Issue:6 Topics: alpha-Synuclein; Glutamine; Histidine; Humans; Male; Middle Aged; Mutation; Parkinson Disease; Pedigree	2013
Residue histidine 50 plays a key role in protecting α-synuclein from aggregation at physiological pH. The Journal of biological chemistry, 2014, May-30, Volume: 289, Issue:22 Topics: alpha-Synuclein; Amino Acid Substitution; Buffers; Electrochemistry; Histidine; Humans; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Parkinson Disease; Unfolded Protein Response	2014
Bioinorganic chemistry of synucleinopathies: deciphering the binding features of Met motifs and His-50 in AS-Cu(I) interactions. Journal of inorganic biochemistry, 2014, Volume: 141 Topics: alpha-Synuclein; Amino Acid Sequence; Binding Sites; Cations, Monovalent; Copper; Histidine; Humans; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Recombinant Proteins; Solutions; Thermodynamics	2014
LC-MS-based urinary metabolite signatures in idiopathic Parkinson's disease. Journal of proteome research, 2015, Jan-02, Volume: 14, Issue:1 Topics: alpha-Synuclein; Animals; Biomarkers; Chromatography, Liquid; Drosophila melanogaster; Fatty Acids; Histidine; Humans; Kynurenine; Mass Spectrometry; Metabolomics; Nucleotides; Parkinson Disease; Phenotype; Phenylalanine; Steroids; Tryptophan; Tyrosine	2015
Posttranslational modification and mutation of histidine 50 trigger alpha synuclein aggregation and toxicity. Molecular neurodegeneration, 2015, Mar-11, Volume: 10 Topics: alpha-Synuclein; Cell Death; Cells, Cultured; Histidine; Humans; Mutation; Neurons; Parkinson Disease; Protein Aggregates; Protein Processing, Post-Translational	2015
Remote His50 Acts as a Coordination Switch in the High-Affinity N-Terminal Centered Copper(II) Site of α-Synuclein. Inorganic chemistry, 2015, May-18, Volume: 54, Issue:10 Topics: alpha-Synuclein; Aspartic Acid; Binding Sites; Copper; Electron Spin Resonance Spectroscopy; Histidine; Humans; Hydrogen-Ion Concentration; Models, Molecular; Peptides; Protein Aggregates; Protein Binding; Protein Folding; Solid-Phase Synthesis Techniques	2015
A Novel Tau Mutation in Exon 12, p.Q336H, Causes Hereditary Pick Disease. Journal of neuropathology and experimental neurology, 2015, Volume: 74, Issue:11 Topics: alpha-Synuclein; Brain; DNA Mutational Analysis; Exons; Glutamic Acid; Histidine; Humans; Male; Middle Aged; Mutation; Pick Disease of the Brain; tau Proteins; Ubiquitin	2015
The Involvement of His50 during Protein Disulfide Isomerase Binding Is Essential for Inhibiting α-Syn Fibril Formation. Biochemistry, 2016, 05-17, Volume: 55, Issue:19 Topics: alpha-Synuclein; Amino Acid Substitution; Amyloid; Animals; Histidine; Humans; Mutation, Missense; Parkinson Disease; Protein Disulfide-Isomerases	2016
Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity. Proceedings of the National Academy of Sciences of the United States of America, 2016, 10-18, Volume: 113, Issue:42 Topics: alpha-Synuclein; Amino Acid Substitution; Animals; Cells, Cultured; Copper; Environment; Genetic Predisposition to Disease; Histidine; Humans; Inclusion Bodies; Kinetics; Mutation; Neurons; Phosphorylation; Protein Aggregates; Protein Aggregation, Pathological; Protein Conformation, alpha-Helical; Rats	2016
D409H GBA1 mutation accelerates the progression of pathology in A53T α-synuclein transgenic mouse model. Acta neuropathologica communications, 2018, 04-27, Volume: 6, Issue:1 Topics: alpha-Synuclein; Animals; Aspartic Acid; Brain Stem; Disease Progression; Endoplasmic Reticulum Stress; Gaucher Disease; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glucosylceramidase; Histidine; Humans; Longevity; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Tyrosine 3-Monooxygenase	2018
Isolated nigral degeneration without pathological protein aggregation in autopsied brains with LRRK2 p.R1441H homozygous and heterozygous mutations. Acta neuropathologica communications, 2018, 10-17, Volume: 6, Issue:1 Topics: Aged; alpha-Synuclein; Astrocytes; Autopsy; DNA-Binding Proteins; Female; Gene Expression Regulation; Histidine; Homozygote; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mutation; Neurodegenerative Diseases; Parkinsonian Disorders; Proline; Protein Aggregation, Pathological; Substantia Nigra; tau Proteins	2018
An efficient method for recombinant production of human alpha synuclein in Preparative biochemistry & biotechnology, 2020, Volume: 50, Issue:7 Topics: alpha-Synuclein; Benzothiazoles; Chromatography, Affinity; Chromatography, High Pressure Liquid; Cloning, Molecular; Endopeptidases; Escherichia coli; Histidine; Humans; Industrial Microbiology; Potyvirus; Recombinant Fusion Proteins; Spectrometry, Fluorescence; Thioredoxins	2020
Comparing the copper binding features of alpha and beta synucleins. Journal of inorganic biochemistry, 2022, Volume: 229 Topics: alpha-Synuclein; Amino Acid Sequence; beta-Synuclein; Binding Sites; Copper; Histidine; Methionine; Protein Binding	2022
Photo-oxygenation of histidine residue inhibits α-synuclein aggregation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023, Volume: 37, Issue:12 Topics: alpha-Synuclein; Histidine; Humans; Lewy Bodies; Parkinson Disease; Respiratory Physiological Phenomena	2023