histidine has been researched along with alpha-chymotrypsin in 206 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 163 (79.13) | 18.7374 |
| 1990's | 23 (11.17) | 18.2507 |
| 2000's | 15 (7.28) | 29.6817 |
| 2010's | 5 (2.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hanai, K | 1 |
| Koeppe, RE; Krieger, M; Stroud, RM | 1 |
| Takahashi, K | 3 |
| Shimamoto, N | 1 |
| Fastrez, J; Houyet, N | 1 |
| Ibañez, IB; Markley, JL | 1 |
| Feeney, RE; Ryan, DS | 1 |
| Chen, SN; Hoffman, MZ | 1 |
| Cruickshank, WH; Kaplan, H | 4 |
| Peters, JR; Schultz, RM; Treadway, WJ; Varma-Nelson, P | 1 |
| Kaletha, K | 1 |
| Fujiwara, K; Tsuru, D | 1 |
| Busby, TF; Gan, JC | 1 |
| Fukutome, H; Kitayama, HP | 1 |
| Sato, S; Uchida, T | 1 |
| Imamura, A; Nagata, C; Umeyama, H | 2 |
| Roberts, MP; York, JL | 1 |
| Axelsen, PH; Sreenivasan, U | 1 |
| Brennan, RG; Dixon, MM; Matthews, BW | 1 |
| Stoeva, S | 1 |
| Horikoshi, N; Natori, S; Sekimizu, K | 1 |
| Leidenberger, F; Willey, KP | 1 |
| Cohen, J; Marcotte, PA; Perun, TJ; Plattner, JJ; Rosenberg, SH; Stein, HH; Woods, KW | 1 |
| Brayer, GD; Delbaere, LT | 1 |
| Allen, RG; Barrett, JT | 1 |
| Lawson, WB; Pattabiraman, TN | 1 |
| Skerrow, D | 1 |
| Mori, H; Murakami, H; Taira, S | 1 |
| Kluh, I; Soliman, MH | 1 |
| Cole, ER | 1 |
| Groskopf, WR; Hsieh, B; Robbins, KC; Summaria, L | 1 |
| Cohen, AB | 1 |
| Anfinsen, CB; Cone, JL; Cusumano, CL; Taniuchi, H | 1 |
| Kosman, DJ | 1 |
| Lissitzky, S; Miranda, F; Rochat, C; Rochat, H; Sampieri, F | 1 |
| Brown, WE; Wold, F | 1 |
| Scott, MD; Sykes, BD | 1 |
| Campbell, LL; Trousil, EB | 1 |
| Klebanov, BM; Trinus, FP | 1 |
| Carson, JH; Gerber, AC; Hadorn, B | 1 |
| Boulter, D; Scawen, MD | 1 |
| Stevenson, KJ | 1 |
| Blow, DM; Henderson, R; Hess, GP; Wright, CS | 1 |
| Robillard, G; Shulman, RG | 4 |
| Hartley, BS | 1 |
| Kopeyan, C; Lissitzky, S; Martinez, G; Miranda, F; Rochat, H | 1 |
| Andersson, B; Nyman, PO; Strid, L | 1 |
| Blow, DM; Hess, GP; Wright, CS | 1 |
| Fife, TH; Hutchins, JE | 1 |
| Heymann, E; Krisch, K | 1 |
| Markussen, J; Sundby, F | 1 |
| Béchet, JJ; Dupaix, A; Robert, JC; Vilkas, M; Wakselman, M; Yon, J | 1 |
| Murphy, D; Salnikow, J | 1 |
| Grey, SM; Nurse, GR; Visser, L | 1 |
| Tulinsky, A; Vandlen, RL | 1 |
| Wright, HT | 1 |
| Gallwitz, U | 1 |
| Havsteen, BH | 1 |
| Keil, B; Keil-Dlouha, V | 1 |
| Ainslie, GR; Barritt, LC; Neet, KE; Sackrison, KM | 1 |
| Folk, JE; Tobita, T | 1 |
| Liener, IE; Smith, RA | 1 |
| Singer, SJ | 1 |
| Keil, B; Kostka, V; Sorm, F; Trufanov, VA | 1 |
| Fahrney, D; Melchior, WB | 1 |
| Christomanos, AA; Dimitriades, A | 1 |
| Jörnvall, H | 1 |
| Baba, Y; Redding, TW; Schally, AV | 1 |
| Arimura, A; Baba, Y; Matsuo, H; Nair, RM; Schally, AV | 1 |
| Sato, S; Tamiya, N | 1 |
| Boeker, EA; Fischer, EH; Snell, EE | 1 |
| Cruickshank, WH; Kaplan, H; Radhakrishnan, TM | 1 |
| Bender, ML; Wedler, FC | 1 |
| Barman, TE | 1 |
| Marini, MA; Martin, CJ; Oza, NB | 1 |
| Cohen, GH; Davies, DR; Powers, JC; Segal, DM; Wilcox, PE | 1 |
| Dunlop, P; Marini, MA; Martin, CJ | 1 |
| Henderson, R | 1 |
| Ruscica, J; Shaw, E | 1 |
| Bender, ML; Valenzuela, P | 1 |
| Bhalla, VK; Robertson, RT; Williams, WL | 1 |
| Furka, A | 1 |
| Bradbury, JH; Chapman, BE; King, NL | 1 |
| Barnard, EA; Kawiak, J; Komender, J; Vensel, WH | 1 |
| Sokolovsky, M; Vallee, BL | 1 |
| Caplow, M | 1 |
| Inada, Y; Matsushima, A; Shibata, K | 1 |
| Barnard, EA; Möckel, W | 2 |
| Blow, DM; Henderson, R; Steitz, TA | 1 |
| Brydon, SE; Neet, KE | 1 |
| Elzinga, M | 2 |
| Husain, SS; Lowe, G | 4 |
| Morihara, K; Oka, T | 1 |
| Cramer, F; Mackensen, G | 1 |
| Smillie, LB; Stevenson, KJ | 3 |
| Gurd, FR; Hugli, TE | 1 |
| Behnke, WD; Neurath, H; Wade, RD | 1 |
| Bender, ML; Nakagawa, Y | 2 |
| Chen, C; Horecker, BL; Lai, CY | 1 |
| Hofstee, BH | 1 |
| Galizzi, A | 1 |
| Lord, RC; Yu, NT | 1 |
| Koehler, KA; Lienhard, GE | 1 |
| Miyatake, A; Wada, H; Watanabe, T | 1 |
| Aune, KC; Timasheff, SN | 1 |
| Hopsu-Havu, VK; Mäkinen, KK | 1 |
| Hoshino, Y | 1 |
| Marini, MA; Martin, CJ | 1 |
| Horecker, BL; Morse, DE | 1 |
| Bonner, J; DeLange, RJ; Fambrough, DM; Smith, EL | 1 |
| Indada, Y; Matsushima, A; Nomoto, M; Sakurai, K; Shibata, K | 1 |
| Blow, DM; Henderson, R; Matthews, BW; Sigler, PB | 1 |
| Alden, RA; Kraut, J; Wright, CS | 1 |
| Birktoft, JJ; Blow, DM; Hartley, BS | 1 |
| Barnard, EA; Hope, WC | 1 |
| Fondy, TP; Ross, CR; Sollohub, SJ | 1 |
| Kaplan, H; Whitaker, DR | 1 |
| Chang, JW; Martin, RB; Tsangaris, JM | 1 |
| Covelli, I; Wolff, J | 1 |
| Hatano, H; Inagami, T | 1 |
| Maddaiah, VT | 1 |
| Biserte, G; Boulanger, Y; Dautrevaux, M; Han, K | 2 |
| Glazer, AN; Sanger, F | 1 |
| Hachimori, Y; Horinishi, H; Kurihara, K; Matsushima, A; Shibata, K | 1 |
| Schramm, HJ | 2 |
| Schöllmann, G | 1 |
| Aoyama, M; Kurihara, K; Shibata, K | 1 |
| Baronowsky, P; Finn, F; Laursen, R; Shafer, J; Westheimer, FH | 1 |
| Kenkare, UW; Richards, FM | 1 |
| Beale, D | 1 |
| Hartley, BS; Smillie, LB | 1 |
| Bender, ML; Kézdy, FJ; Thomson, A | 1 |
| Smillie, LB; Whitaker, DR | 1 |
| Bradbury, JH; Wilairat, P | 1 |
| Dale, BA; Lonsdale-Eccles, JD; Meek, RL; Resing, KA | 1 |
| Genest, M; Ptak, M | 1 |
| Trudelle, Y | 1 |
| Kajita, A; Ohe, M | 1 |
| Frey, PA; Tobin, JB; Whitt, SA | 1 |
| Frey, PA | 1 |
| Gething, MJ; Goldsmith, EJ; Kobe, A; Madison, EL; Sambrook, JF | 1 |
| Bachovchin, WW; Kettner, CA; Tsilikounas, E | 1 |
| Aulak, KS; Davis, AE; Donaldson, VH; Harrison, RA | 1 |
| Ge, SJ; Zhang, LX | 1 |
| Bal, W; Datta, AK; Davis, M; Grbac-Ivankovic, S; Kasprzak, KS; Kotyza, J; Kroftova, OS; Sunderman, FW; Varghese, AH | 1 |
| Berna, PP; Devreese, B; Mrabet, NT; Porath, J; Van Beeumen, J; Vijayalakshmi, MA | 1 |
| Blow, DM | 1 |
| Kaplan, H; Stewart, NA; Taralp, A | 1 |
| Craik, CS; Perona, JJ | 1 |
| McGrath, ME; Mirzadegan, T; Schmidt, BF | 1 |
| Eger, BT; Hynes, RC; Jones, JB; Martichonok, V; Pai, EF; Stoll, VS | 1 |
| Dage, JL; Halsall, HB; Sun, H | 1 |
| Cassidy, CS; Frey, PA; Lin, J | 1 |
| Takeda-Shitaka, M; Umeyama, H | 1 |
| Gráf, L; Kaslik, G; Markley, JL; Westler, WM | 1 |
| Dolinski, K; Heitman, J; Maier, P; Schmid, FX; Scholz, C | 1 |
| Adenier, H; Anissimova, M; Jiang, KY; Pitiot, O; Vijayalakshmi, MA | 1 |
| Bon, C; Braud, S; Maroun, R; Parry, MA; Wisner, A | 1 |
| Engelborghs, Y; Verheyden, G; Volckaert, G | 1 |
| Cope, LD; Fink, DL; Geme, JW; Hansen, EJ | 1 |
| Barrette-Ng, IH; Cherney, MM; Garen, C; Gorbalenya, AE; James, MN; Kolodenko, Y; Mark, BL; Ng, KK; Snijder, EJ; Van Aken, D | 1 |
| Li, S; Norioka, S; Sakiyama, F; Shiraki, K; Yokota, K | 1 |
| Chakrabartty, A; Coomaraswamy, J; Fraser, PE; Goldberg, JM; Lugowski, S; Mastrangelo, P; Petromilli, C; Prusiner, SB; Qin, K; Westaway, D; Yang, Y | 1 |
| GUNDLACH, G; KOEHNE, C; TURBA, F | 1 |
| BARGONI, N; SISINI, A | 1 |
| HERSHEY, JW; KOEHELIK, IH; WOOLLEY, DW | 1 |
| KOSHLAND, DE; RAY, WJ; STRUMEYER, DH | 1 |
| HACHIMORI, Y; HORINISHI, H; KURIHARA, K; SHIBATA, K | 1 |
| MELOUN, B; POSPISILOVA, D | 1 |
| FARINHA, J; GUNDLACH, G; TURBA, F | 1 |
| ONG, EB; SCHOELLMANN, G; SHAW, E | 1 |
| SCHNEIDER, F | 1 |
| RIESER, P | 1 |
| Schutz, CN; Warshel, A | 1 |
| Agger, SA; Davidson, VL; De La Mora-Rey, T; Graichen, ME; Grimsrud, PA; Jones, LH; Marimanikkupam, S; Pearson, AR; Wang, Y; Wilmot, CM | 1 |
| Barbosa, JA; Calderon, Lde A; de Freitas, SM; Guimarães, BG; Medrano, FJ; Santoro, MM; Teles, RC | 1 |
| Akhtar, MS; Bhakuni, V; Mishra, P | 1 |
| Bartik, K; Bruylants, G; Redfield, C | 1 |
| Cosgrove, S; Hewage, C; Malthouse, JP; Rogers, L; Spink, E | 1 |
| Albeck, A; Khazanov, N; Shokhen, M | 2 |
| Baczynski, K; Bista, M; Boulware, KT; Daugherty, PS; Dubin, A; Dubin, G; Enghild, JJ; Kisielewska, M; Popowicz, GM; Potempa, J; Pustelny, K; Stec-Niemczyk, J; Stennicke, HR; Thogersen, IB | 1 |
| Ramsdell, JS; Wang, Z | 1 |
| Aljabali, AA; Evans, DJ; Lomonossoff, GP; Sainsbury, F; Saunders, K | 1 |
| Cleary, JA; Doherty, W; Evans, P; Malthouse, JP | 1 |
| Ericksen, M; Harris, TV; Silverstein, TP; Stratton, A; Symmonds, N | 1 |
| Dastidar, P; Sarkar, K | 1 |
5 review(s) available for histidine and alpha-chymotrypsin
| Article | Year |
|---|---|
Nuclear magnetic resonance studies of the dynamic aspects of molecular structure and interaction in biological systems.
Topics: Aspartate Carbamoyltransferase; Aspirin; Chymotrypsin; Histidine; Ligands; Macromolecular Substances; Magnetic Resonance Spectroscopy; Muramidase; NAD; Penicillin G; Peptides; Protein Binding; Protein Conformation; Protein Denaturation; Ribonucleases; Serum Albumin; Staphylococcus; Sulfonamides; Tryptophan; Valinomycin | 1972 |
[Biochemical mechanisms of the action of non-steroid anti-inflammatory agents (literature review)].
Topics: Adenosine Triphosphate; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Carboxy-Lyases; Chloroquine; Chymotrypsin; Glucose-6-Phosphate Isomerase; Histamine; Histidine; Indomethacin; Kallidin; Kinins; Lactates; Mefenamic Acid; Oxidative Phosphorylation; Peptide Hydrolases; Phenacetin; Phenylbutazone; Quinolines; Rats; Sodium Salicylate | 1972 |
The active centers of serine proteinases.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Cattle; Chymotrypsin; Chymotrypsinogen; Endopeptidases; Histidine; Hydrogen-Ion Concentration; Kinetics; Protein Binding; Protein Conformation; Serine; Solubility; X-Ray Diffraction | 1974 |
Covalent labeling of active sites.
Topics: Amino Acid Sequence; Amino Acids; Antibodies; Binding Sites; Carbon Isotopes; Chymotrypsin; Cysteine; Haptens; Histidine; Isoflurophate; Lysine; Models, Chemical; Phosphoglucomutase; Proteins; Trypsin; Tryptophan; Tyrosine | 1967 |
Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold.
Topics: Aspartic Acid; Binding Sites; Chymotrypsin; Histidine; Lysine; Protein Conformation; Serine; Serine Endopeptidases; Structure-Activity Relationship; Substrate Specificity; Trypsin | 1997 |
201 other study(ies) available for histidine and alpha-chymotrypsin
| Article | Year |
|---|---|
Potentiometric studies on benzeneboronic acid-alpha-chymotrypsin interactions.
Topics: Boronic Acids; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; Models, Chemical; Potentiometry; Protein Binding; Protons; Temperature; Thermodynamics | 1976 |
pH dependence of tritium exchange with the C-2 protons of the histidines in bovine trypsin.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Cattle; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; Isotope Labeling; Kinetics; Mathematics; Peptide Fragments; Protein Binding; Tritium; Trypsin; Trypsin Inhibitor, Kunitz Soybean | 1976 |
The structure and function of ribonuclease T1. XXI. Modification of histidine residues in ribonuclease T1 with iodoacetamide.
Topics: Alanine; Amino Acids; Binding Sites; Chymotrypsin; Guanine Nucleotides; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Iodoacetates; Methylation; Peptides; Ribonuclease T1; Ribonucleases | 1976 |
alpha-chymotrypsin-catalyzed hydrolysis of phenyl acetate. Large Hammett's rho constant and participation of histidine-acylated intermediate.
Topics: Acylation; Chlorobenzenes; Chlorophenols; Chymotrypsin; Deuterium; Histidine; Hydrogen-Ion Concentration; Kinetics; Osmolar Concentration; Phenylacetates; Protein Denaturation; Sodium Dodecyl Sulfate | 1977 |
Mechanism of chymotrypsin: acid/base catalysis and transition-state solvation by the active site.
Topics: Binding Sites; Chymotrypsin; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Kinetics; Temperature; Thermodynamics | 1977 |
Zymogen activation in serine proteinases. Proton magnetic resonance pH titration studies of the two histidines of bovine chymotrypsinogen A and chymotrypsin Aalpha.
Topics: Animals; Cattle; Chymotrypsin; Chymotrypsinogen; Deuterium; Endopeptidases; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Protein Conformation | 1978 |
The interaction of inhibitors of proteolytic enzymes with 3-methylhistidine-57-chymotrypsin.
Topics: Animals; Benzenesulfonates; Benzyl Compounds; Binding Sites; Binding, Competitive; Cattle; Chromatography, Affinity; Chymotrypsin; Ducks; Egg Proteins; Electrophoresis, Starch Gel; Histidine; Kinetics; Mathematics; Mesylates; Methylation; Poultry; Protein Binding; Sepharose; Time Factors; Turkeys | 1975 |
Effect of pH on the reactivity of the carbonate radical in aqueous solution.
Topics: Carbonates; Chymotrypsin; Cysteine; Histidine; Hydrogen-Ion Concentration; Methane; Methionine; Muramidase; Penicillamine; Photochemistry; Propionates; Ribonucleases; Solutions; Tyrosine; Water | 1975 |
Properties of the histidine residues of indole-chymotrypsin. Implications for the activation process and catalytic mechanism.
Topics: Binding Sites; Binding, Competitive; Catalysis; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Activation; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Imidazoles; Indoles; Ligands; Protein Binding | 1975 |
Effect of modification of the essential catalytic residues in alpha-chymotrypsin on the thermodynamics of substrate analog association.
Topics: Acetophenones; Alkylation; Binding Sites; Chymotrypsin; Histidine; Kinetics; Protein Binding; Substrate Specificity; Thermodynamics | 1979 |
[The evaluation of the kinetic constants of enzyme-catalysed reaction with the use of integrated rate equation (author's transl)].
Topics: Ammonia-Lyases; Chymotrypsin; Dipeptides; Histidine; Histidine Ammonia-Lyase; Humans; Hydrolysis; Kinetics; Lysine; Models, Biological; Phenylalanine; Regression Analysis; Substrate Specificity; Trypsin; Tryptophan; Tyrosine | 1979 |
Interaction of methylchymotrypsin with Streptomyces subtilisin inhibitor.
Topics: Bacterial Proteins; Chymotrypsin; Histidine; Kinetics; Mathematics; Methylation; Protein Binding; Spectrophotometry; Spectrophotometry, Ultraviolet; Streptomyces; Substrate Specificity; Subtilisins | 1978 |
Chemical modifications of lysyl and arginyl residues of human plasma alpha1-antitrypsin.
Topics: alpha 1-Antitrypsin; Arginine; Binding Sites; Chymotrypsin; Glyoxal; Histidine; Humans; Immunodiffusion; Ketones; Kinetics; Lysine; Protein Binding | 1976 |
A molecular orbital theoretical study on the acid-base property and reactivity of the charge relay system in alpha chymotrypsin.
Topics: Aspartic Acid; Chymotrypsin; Electric Conductivity; Energy Transfer; Histidine; Hydrogen Bonding; Imidazoles; Models, Chemical; Quantum Theory; Thermodynamics | 1976 |
The amino acid sequence of ribonuclease U2 from Ustilago sphaerogena.
Topics: Amino Acid Sequence; Arginine; Basidiomycota; Chymotrypsin; Endonucleases; Glutamates; Histidine; Hydrolysis; Oxidation-Reduction; Ribonucleases; Thermolysin; Trypsin; Ustilago | 1975 |
A molecular orbital study on the effects of substituents on the proton transfer from ser-195 to his-57 in the hydrolysis of alpha-chymotrypsin.
Topics: Chymotrypsin; Histidine; Hydrogen Bonding; Protein Conformation; Protons; Serine; Thermodynamics | 1975 |
The iron and subunit binding sites of hemerythrin. The role of histidine, tyrosine and tryptophan.
Topics: Binding Sites; Chymotrypsin; Drug Stability; Hemerythrin; Histidine; Iron; Metalloproteins; Oxidation-Reduction; Photochemistry; Protein Binding; Spectrophotometry, Ultraviolet; Tetranitromethane | 1976 |
Buried water in homologous serine proteases.
Topics: Animals; Chymases; Chymotrypsin; Chymotrypsinogen; Crystallization; Histidine; Humans; Hydrogen Bonding; Kallikreins; Molecular Structure; Pancreatic Elastase; Peptidyl-Dipeptidase A; Rats; Serine Endopeptidases; Thrombin; Trypsin; Trypsinogen; Water; X-Ray Diffraction | 1992 |
Structure of gamma-chymotrypsin in the range pH 2.0 to pH 10.5 suggests that gamma-chymotrypsin is a covalent acyl-enzyme adduct at low pH.
Topics: Chymotrypsin; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Structure; Protein Conformation; X-Ray Diffraction | 1991 |
Modification of a zinc proteinase from Bacillus mesentericus strain 76 by diethylpyrocarbonate.
Topics: Amino Acid Sequence; Bacillus; Binding, Competitive; Chymotrypsin; Diethyl Pyrocarbonate; Histidine; Hydroxylamine; Hydroxylamines; Kinetics; Metalloendopeptidases; Molecular Sequence Data; Phenylalanine | 1991 |
Site-directed mutagenesis of arginine 246, glutamic acid 247, and histidine 248 in the eukaryotic transcription factor S-II.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Chymotrypsin; Cloning, Molecular; Escherichia coli; Glutamates; Glutamic Acid; Histidine; Kinetics; Leucine; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Peptide Fragments; Plasmids; Recombinant Proteins; RNA Polymerase II; Transcription Factors; Transcription Factors, General; Transcriptional Elongation Factors | 1990 |
Functionally distinct agonist and receptor-binding regions in human chorionic gonadotropin. Development of a tertiary structure model.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Cell Membrane; Chorionic Gonadotropin; Chymotrypsin; Corpus Luteum; Diethyl Pyrocarbonate; Disulfides; Female; Histidine; Humans; Kinetics; Leydig Cells; Male; Models, Molecular; Molecular Sequence Data; Plasminogen; Protein Conformation; Rats; Receptors, Gonadotropin; Sequence Homology, Nucleic Acid; Steroids | 1989 |
Novel renin inhibitors containing analogues of statine retro-inverted at the C-termini: specificity at the P2 histidine site.
Topics: Amino Acids; Chymotrypsin; Diamines; Histidine; Humans; Renin; Structure-Activity Relationship | 1987 |
The 1.8 A structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Chemical Phenomena; Chemistry; Chymotrypsin; Computers; Crystallography; Endopeptidases; Histidine; Molecular Conformation; Oligopeptides; Protease Inhibitors; Serine Endopeptidases | 1985 |
Antigenic determinants in bovine alpha-chymotrypsin.
Topics: Amino Acids; Animals; Antigens; Cattle; Chymotrypsin; Cross Reactions; Epitopes; Histidine; Immune Sera; Ketones; Methionine; Precipitin Tests; Serine; Sulfonamides; Toluene; Urea | 1970 |
Stereochemistry of the active site of -chymotrypsin. The effect of some tricyclic bromomethyl ketones on -chymotrypsin.
Topics: Alkylation; Binding Sites; Bromine; Catalysis; Chymotrypsin; Furans; Histidine; Ketones; Naphthols; Polycyclic Compounds; Stereoisomerism; Time Factors | 1972 |
A repeating subunit of soluble prekeratin.
Topics: Amino Acids; Animals; Cattle; Chromatography, Paper; Chymotrypsin; Cystine; Electrophoresis, Paper; Histidine; Keratins; Macromolecular Substances; Methionine; Molecular Weight; Nose; Peptides; Proteins; Skin; Staining and Labeling; Trypsin; Tryptophan; Tyrosine | 1972 |
Active centre model on the structure and function of the bleomycin molecule as the prototype of esteratic enzymes.
Topics: Animals; Binding Sites; Bleomycin; Chymotrypsin; Copper; DNA; Esterases; Guanine; Histidine; Imidazoles; Models, Chemical; Models, Structural; Molecular Conformation; Oxidation-Reduction; Pancreas; Photochemistry; Protein Denaturation; Ribonucleases; Rose Bengal; Salmon; Spectrophotometry; Temperature; Threonine; Viscosity; Zinc | 1973 |
Isolation of carbonic anhydrase from dog erythrocytes and determination of its N-terminal amino-acid sequence.
Topics: Amino Acid Sequence; Amino Acids; Animals; Benzoates; Carbonic Anhydrases; Carboxypeptidases; Cattle; Chymotrypsin; Disulfides; Dogs; Electrophoresis, Disc; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Erythrocytes; Histidine; Horses; Humans; Nitro Compounds; Phenylalanine; Serine; Species Specificity; Tryptophan; Ultracentrifugation | 1974 |
Hydrolysis of L-histidine methyl ester. II. Activity of various proteolytic enzymes with special reference to activators of human plasminogen.
Topics: Animals; Bromelains; Cattle; Chymotrypsin; Esters; Fibrinolysin; Fibrinolytic Agents; Histidine; Papain; Peptide Hydrolases; Plasminogen; Streptokinase; Thrombin; Trypsin | 1968 |
Studies on the active center of human plasmin. The serine and histidine residues.
Topics: Amino Acids; Autoanalysis; Autoradiography; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chymotrypsin; Electrophoresis; Fibrinolysin; Fibrinolytic Agents; Histidine; Humans; Isoflurophate; Ketones; Kinetics; Methods; Methylation; Oxidation-Reduction; Peptides; Phosphorus Isotopes; Plasminogen; Protein Hydrolysates; Serine; Trypsin | 1969 |
Mechanism of action of alpha-1-antitrypsin.
Topics: alpha 1-Antitrypsin; Amino Acids; Anilides; Arginine; Aspartic Acid; Benzoates; Binding Sites; Binding, Competitive; Cholinesterase Inhibitors; Chymotrypsin; Fibrinolysin; Glyoxal; Histidine; Isoflurophate; Leucine; Lysine; Nitro Compounds; Pancreatic Elastase; Peptide Hydrolases; Protease Inhibitors; Serine; Structure-Activity Relationship; Subtilisins; Thrombin; Trypsin Inhibitors | 1973 |
Staphylococcal nuclease (Foggi strain). II. The amino acid sequence.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Chromatography, Ion Exchange; Chymotrypsin; Cyanides; Glutamates; Histidine; Leucine; Peptides; Phosphoric Monoester Hydrolases; Staphylococcus; Trypsin | 1971 |
Electron paramagnetic resonance probing of macromolecules: a comparison of structure-function relationships in chymotrypsinogen, -chymotrypsin and anhydrochymotrypsin.
Topics: Acetamides; Acylation; Chymotrypsin; Chymotrypsinogen; Electron Spin Resonance Spectroscopy; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Imidazoles; Indoles; Kinetics; Macromolecular Substances; Methionine; Protein Conformation; Rotation; Serine; Spectrum Analysis; Structure-Activity Relationship; Tosyl Compounds | 1972 |
The amino-acid sequence of neurotoxin II of Androctonus australis Hector.
Topics: Amino Acid Sequence; Autoanalysis; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Chymotrypsin; Cystine; Fluoroacetates; Histidine; Hydrolysis; Methylation; Peptides; Periodic Acid; Scorpions; Thiocyanates; Toxins, Biological; Trypsin | 1972 |
Alkyl isocyanates as active-site-specific reagents for serine proteases. Reaction properties.
Topics: Acetone; Binding Sites; Carbon Isotopes; Chymotrypsin; Chymotrypsinogen; Cyanates; Drug Stability; Endopeptidases; Histidine; Hydrogen-Ion Concentration; Indoles; Kinetics; Microbial Collagenase; Models, Chemical; Pancreatic Elastase; Papain; Pepsin A; Protease Inhibitors; Serine; Structure-Activity Relationship; Trypsin; X-Ray Diffraction | 1973 |
Amino acid sequence of cytochrome c3 from Desulfovibrio vulgaris.
Topics: Amino Acid Sequence; Amino Acids; Apoproteins; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Chymotrypsin; Cysteine; Cytochrome c Group; Desulfovibrio; Heme; Histidine; Peptide Fragments; Peptides; Thiocyanates; Trypsin | 1974 |
Partial purification and characterization of a chymotrypsin-like enzyme from human neutrophil leucocytes.
Topics: Binding Sites; Chromatography, Gel; Chymotrypsin; Dithioerythritol; Electrophoresis, Polyacrylamide Gel; Histidine; Humans; Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Molecular Weight; Neutrophils; Organ Specificity; Oxidation-Reduction; Pancreas; Phenylalanine; Phosphorus Radioisotopes; Protein Binding; Serine; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tosyl Compounds; Ultracentrifugation | 1974 |
The amino acid sequence of plastocyanin from Cucurbita pepo L. (vegetable marrow).
Topics: Amino Acid Sequence; Chymotrypsin; Cyanogen Bromide; Dansyl Compounds; Glutamates; Histidine; Molecular Weight; Peptides; Plant Proteins; Plants; Plastocyanin; Thiocyanates; Trypsin | 1974 |
The selective isolation of an active-site histidine peptide from chymotrypsin-alpha by diagonal peptide 'mapping'. An N-tau-carboxymethylhistidine diagonal peptide "mapping.".
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Chymotrypsin; Electrophoresis, Paper; Histidine; Nitriles; Oxidation-Reduction; Peptide Fragments; Subtilisins; Tosylphenylalanyl Chloromethyl Ketone | 1974 |
-Chymotrypsin: what can we learn about catalysis from x-ray diffraction?
Topics: Acetates; Acridines; Acylation; Benzyl Compounds; Binding Sites; Catalysis; Chymotrypsin; Formates; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Isomerism; Methylation; Models, Structural; Nitrophenols; Phenylalanine; Protein Conformation; Spectrophotometry; Structure-Activity Relationship; Tryptophan; Tyrosine; X-Ray Diffraction | 1972 |
High resolution NMR study of the charge relay system in chymotrypsin.
Topics: Binding Sites; Boronic Acids; Chymotrypsin; Chymotrypsinogen; Histidine; Hydrogen; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Protein Binding; Protein Conformation; Structure-Activity Relationship; Temperature | 1973 |
Properties of the active center histidine of -chymotrypsin.
Topics: Acetates; Amino Acids; Binding Sites; Catalysis; Chromatography; Chymotrypsin; Electrophoresis; Fluorine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Mathematics; Nitrobenzenes; Oxidation-Reduction; Pepsin A; Peptides; Tritium | 1972 |
Disulfide bonds of toxin II of the scorpion Androctonus australis Hector.
Topics: Amino Acid Sequence; Amino Acids; Autoanalysis; Chromatography, Gel; Chromatography, Paper; Chymotrypsin; Cystine; Dansyl Compounds; Disulfides; Electrophoresis, Paper; Histidine; Hydrolysis; Pepsin A; Peptide Fragments; Protein Conformation; Scorpions; Thermolysin; Toxins, Biological; Trypsin; Tryptophan | 1974 |
Amino acid sequence of human erythrocyte carbonic anhydrase B.
Topics: Amidines; Amino Acid Sequence; Aminopeptidases; Binding Sites; Carbonic Anhydrases; Carboxypeptidases; Chromatography, Gel; Chymotrypsin; Dansyl Compounds; Electrophoresis, Paper; Endopeptidases; Erythrocytes; Histidine; Humans; Leucyl Aminopeptidase; Papain; Peptides; Protein Binding; Thermolysin; Thiocyanates; Trypsin; X-Ray Diffraction; Zinc | 1972 |
Structure of crystalline methyl-chymotrypsin.
Topics: Acetates; Ammonium Sulfate; Binding Sites; Carbon Isotopes; Chromatography, Ion Exchange; Chymotrypsin; Crystallization; Histidine; Indoles; Mathematics; Methylation; Models, Structural; Nitrobenzenes; Nitrophenols; Protein Binding; Protein Conformation; Serine; Sulfonic Acids; Tosyl Compounds; Tryptophan; Ultrafiltration; X-Ray Diffraction | 1972 |
High resolution nuclear magnetic resonance study of the histidine--aspartate hydrogen bond in chymotrypsin and chymotrypsinogen.
Topics: Aspartic Acid; Binding Sites; Chymotrypsin; Chymotrypsinogen; Histidine; Hydrogen; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Biology | 1972 |
Deacylation of acyl chymotrypsins formed from aromatic carbonate diesters. Evidence for hindered nucleophilic attack by histidine-57.
Topics: Acylation; Carbonates; Chymotrypsin; Dealkylation; Histidine; Kinetics; Nitrophenols | 1972 |
A competitive labelling method for determining the ionization constants and reactivity of individual histidine residues in proteins. The histidines of -chymotrypsin.
Topics: Chemical Phenomena; Chemistry; Chymotrypsin; Fluorides; Histidine; Hydrogen-Ion Concentration; Imidazoles; Ions; Isotope Labeling; Nitrobenzenes; Peptides; Protein Conformation; Serine; Tritium | 1972 |
[Inhibition of carboxylesterase from pig liver by substrate-analogue alkylating agents and amino-group specific reagents].
Topics: Acetophenones; Animals; Butyrates; Carboxylic Acids; Chymotrypsin; Esterases; Esters; Fluorenes; Histidine; Ketones; Liver; Mercaptoethanol; Methylation; Nitrobenzenes; Swine | 1972 |
Isolation and amino-acid sequence of the C-peptide of duck proinsulin.
Topics: Amino Acid Sequence; Animals; Autoanalysis; Biological Evolution; Carboxypeptidases; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chymotrypsin; Ducks; Histidine; Leucyl Aminopeptidase; Pancreas; Peptides; Phenylalanine; Proinsulin; Tyrosine | 1973 |
Inactivation of alpha-chymotrypsin by a bifunctional reagent, 3,4-dihydro-3,4-dibromo-6-bromomethylcoumarin.
Topics: Acetylation; Acridines; Alkylation; Amines; Binding Sites; Bromine; Chemical Phenomena; Chemistry; Chymotrypsin; Coumarins; Esters; Histidine; Hydrogen-Ion Concentration; Protein Binding; Serine; Structure-Activity Relationship | 1973 |
Bovine pancreatic deoxyribonucleases A and C. A proline for histidine substitution in deoxyribonuclease C.
Topics: Amino Acid Sequence; Amino Acids; Animals; Carboxypeptidases; Cattle; Chromatography, Paper; Chymotrypsin; Deoxyribonucleases; Electrophoresis, Paper; Histidine; Pancreas; Peptides; Proline; Trypsin | 1973 |
Implications of the chemical modification of chymotrypsin.
Topics: Acetamides; Alkylation; Amino Acids; Animals; Butanones; Catalysis; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Circular Dichroism; Glutamates; Histidine; Hydrogen-Ion Concentration; Iodoacetates; Mercaptoethanol; Nitrobenzenes; Pancreatic Elastase; Peptides; Ultraviolet Rays | 1973 |
Changes in the tertiary structure of alpha-chymotrypsin with change in pH: p4 4.2-6.7.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; Macromolecular Substances; Methionine; Models, Structural; Phenylalanine; Protein Binding; Protein Conformation; Serine; Tyrosine; Uranium; X-Ray Diffraction | 1973 |
Activation of chymotrypsinogen-A. An hypothesis based upon comparison of the crystal structures of chymotrypsinogen-A and alpha-chymotrypsin.
Topics: Aspartic Acid; Catalysis; Chymotrypsin; Chymotrypsinogen; Enzyme Activation; Histidine; Orientation; Protein Binding; Protein Conformation | 1973 |
Localisation of the three amino acid exchanges in the coat-protein of TMV-06.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Carboxypeptidases; Chromatography, Paper; Chymotrypsin; Cyanogen Bromide; Dansyl Compounds; Electrophoresis, Paper; Histidine; Methionine; Mutation; Peptide Fragments; Tobacco Mosaic Virus; Trypsin; Viral Proteins | 1973 |
A molecular orbital study on the enzymic reaction mechanism of alpha-chymotrypsin.
Topics: Acetamides; Acetates; Activation Analysis; Acylation; Aspartic Acid; Chymotrypsin; Histidine; Hydrolysis; Molecular Biology; Protein Binding; Quantum Theory; Serine; X-Ray Diffraction | 1973 |
Chemical modification in the active site of delta-chymotrypsin.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis, Paper; Histidine; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Malonates; Mass Spectrometry; Methionine; Methods; Molecular Weight; Peptide Fragments; Peptides; Spectrophotometry, Ultraviolet; Time Factors; Ultracentrifugation | 1973 |
Consequences of the modification of tryptophan-215 on the function of bovine alpha-chymotrypsin.
Topics: Animals; Benzene Derivatives; Benzyl Compounds; Binding Sites; Catalysis; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Histidine; Humans; Indicators and Reagents; Organophosphorus Compounds; Phenols; Phosphates; Propane; Protein Conformation; Serine; Trypsin Inhibitors; Tryptophan | 1973 |
Properties of the histidines of chymotrypsinogen: comparison with alpha-chymotrypsin.
Topics: Binding, Competitive; Catalysis; Chymotrypsin; Chymotrypsinogen; Electric Conductivity; Fluorobenzenes; Histidine; Hydrogen-Ion Concentration; Nitrobenzenes; Protein Binding; Protein Conformation; Tritium | 1974 |
Conformational changes and association of chemically modified chymotrypsins.
Topics: Benzenesulfonates; Binding Sites; Chromatography, Gel; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; Methionine; Molecular Weight; Nitro Compounds; Optical Rotatory Dispersion; Phenols; Protein Binding; Protein Conformation; Serine; Spectrophotometry, Ultraviolet; Tosyl Compounds; Ultracentrifugation | 1974 |
High resolution nuclear magnetic resonance studies of the active site of chymotrypsin. I. The hydrogen bonded protons of the "charge relay" system.
Topics: Aspartic Acid; Binding Sites; Chymotrypsin; Chymotrypsinogen; Deuterium; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Serine | 1974 |
High resolution nuclear magnetic resonance studies of the active site of chymotrypsin. II. Polarization of histidine 57 by substrate analogues and competitive inhibitors.
Topics: Aspartic Acid; Binding Sites; Boric Acids; Boronic Acids; Carboxylic Acids; Chymotrypsin; Chymotrypsinogen; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Subtilisins; Trypsin Inhibitors | 1974 |
Chymotrypsin C. 3. Sequence of amino acids around an essential histidine residue.
Topics: Amino Acid Sequence; Amino Acids; Carbon Isotopes; Carboxypeptidases; Chromatography, Gel; Chymotrypsin; Electrophoresis; Histidine; Leucyl Aminopeptidase; Pepsin A; Peptide Hydrolases; Peptides; Protein Hydrolysates | 1967 |
Amino acid sequences involving the histidine residues of porcine trypsin.
Topics: Amino Acid Sequence; Animals; Autoanalysis; Binding Sites; Cattle; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis; Histidine; Oxidation-Reduction; Pepsin A; Peptides; Protein Hydrolysates; Swine; Trypsin | 1967 |
N-Terminal fragment of hog pepsin.
Topics: Alkylation; Amines; Amino Acids; Animals; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cyanides; Cystine; Densitometry; Dextrans; Dinitrophenols; Electrophoresis, Disc; Histidine; Isoleucine; Naphthalenes; Pepsin A; Peptides; Protein Hydrolysates; Sulfonic Acids; Swine; Trypsin | 1969 |
Ethoxyformylation of proteins. Reaction of ethoxyformic anhydride with alpha-chymotrypsin, pepsin, and pancreatic ribonuclease at pH 4.
Topics: Amino Acids; Anhydrides; Animals; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Enzyme Activation; Enzyme Precursors; Esters; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; Imidazoles; Kinetics; Nitrobenzenes; Osmolar Concentration; Pancreas; Pepsin A; Proteins; Ribonucleases; Sulfonic Acids; Swine; Time Factors | 1970 |
On the chemical structure of antigens and antibodies bound to fluorescent dyes. I. Structure of the antihuman gamma-globulin of the goat bound to the fluorochrome lissamine rhodamine B.
Topics: Amino Acids; Animals; Antibodies, Anti-Idiotypic; Antigens; Arginine; Aspartic Acid; Chromatography, Paper; Chymotrypsin; Electrophoresis; Fluorescent Dyes; Fluorometry; Goats; Histidine; Lysine; Oxidation-Reduction; Pepsin A; Protein Binding; Serine; Sulfides; Trypsin; Tryptophan; Tyrosine | 1966 |
Horse liver alcohol dehydrogenase. The primary structure of the protein chain of the ethanol-active isoenzyme.
Topics: Alcohol Oxidoreductases; Alkylation; Amino Acid Sequence; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chymotrypsin; Cyanides; Cysteine; Ethanol; Histidine; Horses; Iodoacetates; Isoenzymes; Liver; Malates; Methionine; Mutation; Pepsin A; Peptides; Serine; Trypsin | 1970 |
Studies on the enzymatic and chemical inactivation of hypothalamic follicle-stimulating hormone-releasing hormone.
Topics: Amino Acid Sequence; Aniline Compounds; Animals; Chemical Phenomena; Chemistry; Chromatography, Gel; Chymotrypsin; Endopeptidases; Follicle Stimulating Hormone; Formates; Histidine; Hydrochloric Acid; Papain; Pituitary Hormone-Releasing Hormones; Pyrrolidinones; Sulfonic Acids; Swine; Tryptophan; Tyrosine | 1971 |
Structure of the porcine LH- and FSH-releasing hormone. I. The proposed amino acid sequence.
Topics: Acetates; Amino Acid Sequence; Amino Acids; Anhydrides; Animals; Arginine; Chemical Phenomena; Chemistry; Chymotrypsin; Endopeptidases; Follicle Stimulating Hormone; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Hypothalamus; Leucine; Luteinizing Hormone; Mass Spectrometry; Methods; Naphthalenes; Peptides; Pituitary Hormone-Releasing Hormones; Proline; Serine; Sulfonic Acids; Swine; Thiocyanates; Tritium; Tryptophan; Tyrosine | 1971 |
The amino acid sequences of erabutoxins, neurotoxic proteins of sea-snake (Laticauda semifasciata) venom.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspergillus; Chromatography; Chymotrypsin; Electrophoresis; Histidine; Hydrolysis; Pepsin A; Peptide Hydrolases; Peptides; Proteins; Snakes; Tritium; Trypsin; Venoms | 1971 |
Arginine decarboxylase from Escherichia coli. IV. Structure of the pyridoxal phosphate binding site.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Amino Acids; Arginine; Autoanalysis; Binding Sites; Borohydrides; Carbon Isotopes; Carboxy-Lyases; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chymotrypsin; Dansyl Compounds; Escherichia coli; Fluorescence; Glutamates; Histidine; Lysine; Methods; Oxidation-Reduction; Peptides; Pyridoxal Phosphate; Schiff Bases; Thiocyanates; Trypsin | 1971 |
A diagonal paper electrophoretic method for the selective isolation of histidyl peptides.
Topics: Chemical Phenomena; Chemistry; Chymotrypsin; Electrophoresis, Paper; Fluorine; Formates; Histidine; Hydrogen-Ion Concentration; Maleates; Mercaptoethanol; Methods; Nitrobenzenes; Oxidation-Reduction; Pepsin A; Peptides; Trypsin | 1971 |
Evidence for the His-57 sidechain acting as a general base in the "ageing" and reactivation reactions of carbonate-inhibited -chymotrypsin.
Topics: Binding Sites; Carbonates; Chymotrypsin; Enzyme Activation; Esters; Histidine; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Nitrophenols; Phosphoric Acids | 1972 |
The modification of the tryptophan residues of bovine alpha-lactalbumin with 2-hydroxy-5-nitrobenzyl bromide and with dimethyl(2-hydroxy-5-nitrobenzyl)sulphonium bromide.
Topics: Albumins; Alkylation; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chymotrypsin; Electrophoresis, Paper; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Milk; Nitrobenzenes; Oxidation-Reduction; Peptides; Phenols; Sulfur; Trypsin; Tryptophan | 1972 |
Formaldehyde as an active site label of -chymotrypsin.
Topics: Acetates; Binding Sites; Binding, Competitive; Catalysis; Chemical Phenomena; Chemistry; Chymotrypsin; Esters; Formaldehyde; Histidine; Imidazoles; Kinetics; Mathematics; Nitrobenzenes; Osmolar Concentration; Spectrophotometry; Tyrosine | 1972 |
Substrate binding site in bovine chymotrypsin A-gamma. A crystallographic study using peptide chloromethyl ketones as site-specific inhibitors.
Topics: Acylation; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Chlorine; Chymotrypsin; Chymotrypsinogen; Crystallography; Electrons; Histidine; Isoleucine; Ketones; Mathematics; Models, Structural; Peptides; Phenylalanine; Serine; X-Ray Diffraction | 1971 |
The reaction of -, -, and acetylated- -chymotrypsin with radioactive formaldehyde.
Topics: Acetates; Acylation; Carbon Isotopes; Chemical Phenomena; Chemistry; Chymotrypsin; Formaldehyde; Histidine; Hydrogen-Ion Concentration; Imidazoles; Isoleucine; Protein Binding; Spectrophotometry; Ultraviolet Rays | 1971 |
Catalytic activity of -chymotrypsin in which histidine-57 has been methylated.
Topics: Acridines; Acylation; Amides; Catalysis; Chromatography; Chymotrypsin; Esters; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Methylation; Nitrophenols; Serine | 1971 |
The reactivity of His-57 in chymotrypsin to alkylation.
Topics: Acetates; Alkylation; Benzyl Compounds; Bromine; Chemical Phenomena; Chemistry; Chlorine; Chymotrypsin; Formates; Histidine; Ketones; Kinetics; Phenylalanine; Sulfonic Acids; Toluene | 1971 |
Kinetic properties of succinylated and ethylenediamine-amidated -chymotrypsins.
Topics: Acetates; Acrylates; Catalysis; Chemical Phenomena; Chemistry; Chymotrypsin; Chymotrypsinogen; Computers; Enzyme Activation; Ethylenediamines; Furans; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Imides; Isoleucine; Kinetics; Methylamines; Phenylalanine; Protein Conformation; Succinates; Trypsin; Tryptophan | 1971 |
Purification and the peptide nature of decapacitation factor.
Topics: Amides; Animals; Arginine; Aspartic Acid; Carboxypeptidases; Cattle; Cellulose; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Contraceptive Agents; Histidine; Hydrolysis; Male; Methods; Peptides; Pronase; Resins, Plant; Semen; Trypsin; Ultracentrifugation | 1971 |
Group separation: a new method facilitating isolation of peptides from digests of high molecular weight proteins.
Topics: Anhydrides; Arginine; Carboxypeptidases; Chromatography, Ion Exchange; Chymotrypsin; Cysteine; Endopeptidases; Histidine; Imides; Lysine; Maleates; Methionine; Methods; Peptides; Phosphoproteins; Proteins; Serine; Trypsin | 1971 |
Line widths of proton magnetic resonance spectra of proteins in solution.
Topics: Albumins; Animals; Catalase; Cattle; Cetacea; Chymotrypsin; Deuterium; Egg White; Histidine; Insulin; Liver; Magnetic Resonance Spectroscopy; Mathematics; Methionine; Muramidase; Myoglobin; Pancreatic Elastase; Protein Denaturation; Proteins; Ribonucleases; Serum Albumin, Bovine; Trypsin | 1971 |
Non-pancreatic proteases of the chymotrypsin family. I. A chymotrypsin-like protease from rat mast cells.
Topics: Acrylates; Animals; Arginine; Benzoates; Binding Sites; Cell Count; Cell Fractionation; Cell Nucleus; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Dextrans; Endopeptidases; Enzyme Precursors; Esters; Gels; Histidine; Hydrogen-Ion Concentration; Isoflurophate; Ketones; Kinetics; Male; Mast Cells; Methods; Microscopy, Electron; Molecular Weight; Osmolar Concentration; Peritoneal Cavity; Phosphorus Isotopes; Potassium Chloride; Rats; Serine; Sulfonic Acids; Toluene; Tritium; Tyrosine | 1971 |
The reaction of diazonium-1H-tetrazole with proteins. Determination of tyrosine and histidine content.
Topics: Azo Compounds; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; Insulin; Ovalbumin; Pepsin A; Proteins; Ribonucleases; Spectrophotometry; Tetrazolium Salts; Trypsin; Tyrosine | 1966 |
Substrate structure effects on the pH dependence of deacylation of acyl-chymotrypsins.
Topics: Amines; Chemical Phenomena; Chemistry; Chymotrypsin; Histidine; Hydrogen-Ion Concentration | 1969 |
Tyrosine, histidineand tryptophan residues in TPCK-modifiechymotrypsin.
Topics: Azoles; Biochemical Phenomena; Biochemistry; Chymotrypsin; Histidine; Hydrogen Peroxide; Tryptophan; Tyrosine | 1969 |
Isolation and properties of two chymotrypsins from the turtle Pseudemys elegans.
Topics: Amino Acids; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis; Enzyme Activation; Enzyme Precursors; Histidine; Kinetics; Methods; Methylcellulose; Molecular Weight; Pancreas; Peptides; Quaternary Ammonium Compounds; Trypsin; Turtles; Tyrosine | 1969 |
Structure of crystalline alpha-chymotrypsin. 3. Crystallographic studies of substrates and inhibitors bound to the active site of alpha-chymotrypsin.
Topics: Arginine; Aspartic Acid; Binding Sites; Chymotrypsin; Histidine; Indoles; Lysine; Molecular Biology; Peptides; Protein Binding; Serine; Toluene; Trypsin; Tryptophan; X-Ray Diffraction | 1969 |
Amino acids around an active center histidine in a turtle chymotrypsin.
Topics: Alkylating Agents; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Carbon Isotopes; Carboxypeptidases; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chymotrypsin; Electrophoresis; Histidine; Pancreas; Peptides; Species Specificity; Swine; Turtles | 1969 |
Sedimentation of chemically modified chymotrypsin.
Topics: Acetates; Amino Acid Sequence; Amino Acids; Chemical Phenomena; Chemistry; Chymotrypsin; Cinnamates; Guanidines; Histidine; Hydrogen-Ion Concentration; Lysine; Methionine; Serine; Sulfonic Acids; Toluene; Ultracentrifugation | 1970 |
Amino acid sequence studies on rabbit skeletal muscle actin. Cyanogen bromide cleavage of the protein and determination of the sequences of seven of the resulting peptides.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Aminopeptidases; Animals; Autoanalysis; Carboxypeptidases; Cellulose; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cyanides; Cysteine; Endopeptidases; Histidine; Methods; Molecular Weight; Muscle Proteins; Peptides; Rabbits; Trypsin; Tryptophan | 1970 |
The amino acid sequence around the active-site cysteine and histidine residues, and the buried cysteine residue in ficin.
Topics: Acetone; Amino Acid Sequence; Binding Sites; Carbon Isotopes; Chromatography; Chymotrypsin; Cysteine; Histidine; Methylcellulose; Papain; Peptide Hydrolases; Protease Inhibitors; Rubber; Trypsin | 1970 |
The amino acid sequence around the active-site cysteine and histidine residues of stem bromelain.
Topics: Amino Acid Sequence; Bromelains; Carbon Isotopes; Chymotrypsin; Cysteine; Histidine; Iodoacetates; Papain; Peptide Hydrolases; Plants, Edible; Trypsin | 1970 |
Subtilisin BPN': inactivation by chloromethyl ketone derivates of peptide substrates.
Topics: Amino Acids; Bacillus; Binding Sites; Chymotrypsin; Cinnamates; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Ketones; Kinetics; Peptides; Protease Inhibitors | 1970 |
[Cyclodextrin-imidazole compounds].
Topics: Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Chymotrypsin; Histidine; Imidazoles; Models, Chemical; Models, Structural; Polysaccharides; Serine | 1970 |
A reinvestigation of residues 64-68 and 175 in papain. Evidence that residues 64 and 175 are asparagine.
Topics: Amino Acid Sequence; Asparagine; Binding Sites; Chromatography, Gel; Chymotrypsin; Cysteine; Histidine; Imidazoles; Papain; Protein Binding | 1970 |
The inhibition of chymotrypsin A4 with a homologous series of chloromethyl ketone reagents.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Benzene Derivatives; Binding Sites; Chemical Phenomena; Chemistry; Chlorine; Chymotrypsin; Electrophoresis; Histidine; Hydrogen-Ion Concentration; Ketones; Kinetics; Methionine; Peptides; Sulfonic Acids | 1970 |
Carboxymethylation of sperm whale myoglobin in the crystalline state.
Topics: Acetates; Alkylation; Amino Acid Sequence; Amino Acids; Animals; Cetacea; Chromatography, Ion Exchange; Chromatography, Paper; Chymotrypsin; Crystallization; Electrophoresis; Histidine; Lysine; Methionine; Myoglobin; Peptides; Trypsin; Valine | 1970 |
Interactions of the endopeptidase subunit of bovine procarboxypeptidase A-S6.
Topics: Amino Acids; Animals; Binding Sites; Butanones; Carbon Isotopes; Carboxypeptidases; Cattle; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Cinnamates; Electrophoresis, Disc; Endopeptidases; Enzyme Activation; Enzyme Precursors; Formates; Histidine; Imidazoles; Isoflurophate; Molecular Weight; Pancreas; Peptides; Phosphorus Isotopes; Serine; Trypsin | 1970 |
Methylation of histidine-57 in alpha-chymotrypsin by methyl p-nitrobenzenesulfonate. A new approach to enzyme modification.
Topics: Amino Acids; Animals; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Chromatography, Paper; Chymotrypsin; Cinnamates; Drug Stability; Electrophoresis; Histidine; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Methods; Methylation; Nitrobenzenes; Peptides; Protease Inhibitors; Spectrophotometry; Sulfonic Acids; Swine; Trypsin Inhibitors; Tryptophan; Ultraviolet Rays | 1970 |
Primary structure of two COOH-terminal hexapeptides from rabbit muscle aldolase: a difference in the structure of the alpha and beta subunits.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Aspartic Acid; Carboxypeptidases; Chromatography, Ion Exchange; Chymotrypsin; Fructose-Bisphosphate Aldolase; Histidine; Muscles; Rabbits; Trypsin; Tyrosine | 1970 |
Effects of neutralization of amino groups on the kinetics of chymotrypsin.
Topics: Amines; Benzoates; Binding Sites; Carbamates; Chemical Phenomena; Chemistry; Chymotrypsin; Enzyme Activation; Enzyme Precursors; Hippurates; Histidine; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Lysine; Osmolar Concentration | 1970 |
The amino acid sequence of the beta-chains of rabbit hemoglobin.
Topics: Amino Acid Sequence; Animals; Asparagine; Chromatography, Ion Exchange; Chymotrypsin; Hemoglobins; Histidine; Leucyl Aminopeptidase; Peptides; Rabbits; Serine; Trypsin | 1970 |
Laser-excited Raman spectroscopy of biomolecules. II. Native ribonuclease and alpha-chymotrypsin.
Topics: Amides; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Cystine; Deuterium; Glutamates; Histidine; Hydrogen-Ion Concentration; Lasers; Muramidase; Peptides; Phenylalanine; Protein Denaturation; Ribonucleases; Spectrum Analysis; Sulfides; Tryptophan; Tyrosine | 1970 |
Amino acid sequence aroung 3-methylhistidine in rabbit skeletal muscle actin.
Topics: Amino Acid Sequence; Amino Acids; Animals; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Histidine; Muscle Proteins; Peptides; Rabbits | 1971 |
The structure and function of ribonuclease T1. XII. Further studies on rose bengal-catalyzed photooxidation of ribonuclease T1--identification of a critical histidine residue.
Topics: Adenine Nucleotides; Amino Acids; Autoanalysis; Catalysis; Chymotrypsin; Cytosine Nucleotides; Electrophoresis; Guanine Nucleotides; Histidine; Hydrogen-Ion Concentration; Light; Oxidation-Reduction; Peptides; Ribonucleases; Rose Bengal | 1971 |
2-phenylethaneboronic acid, a possible transition-state analog for chymotrypsin.
Topics: Acylation; Amides; Binding Sites; Boronic Acids; Catalysis; Chemical Phenomena; Chemistry; Chymotrypsin; Cinnamates; Hippurates; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Serine; Sulfonic Acids | 1971 |
Comparative studies on the primary structure of soluble and mitochondrial glutamic oxaloacetic transaminase isozymes. II. Amino acid sequence of the amino terminal fragments.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aminobutyrates; Animals; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Chromatography, Paper; Chymotrypsin; Cyanides; Endopeptidases; Glutamates; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Hydroxybutyrates; Isoenzymes; Mitochondria, Muscle; Myocardium; Peptides; Phenylalanine; Proline; Serine; Solubility; Swine; Thiocyanates; Tryptophan; Valine | 1971 |
Dimerization of alpha-chymotrypsin. I. pH dependence in the acid region.
Topics: Amino Acid Sequence; Chemical Phenomena; Chemistry; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; Imidazoles; Mathematics; Polymers; Spectrophotometry; Tyrosine; Ultracentrifugation; Ultraviolet Rays | 1971 |
The active centre of aminopeptidase B. I. The effects of various chemical reagents.
Topics: Aminopeptidases; Animals; Benzene; Binding Sites; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Chymotrypsin; Cysteine; Glucose; Histidine; Imidazoles; Light; Mercury; Methylene Blue; Oxidation-Reduction; Rats; Sulfhydryl Compounds | 1967 |
Studies on absorption of leucomycin from intestinal tract.
Topics: Animals; Anti-Bacterial Agents; Bile Acids and Salts; Caproates; Chymotrypsin; Dinitrophenols; Fatty Acids; Histidine; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Male; Methods; Mice; Pyridoxal Phosphate; Sulfathiazoles; Tissue Extracts | 1967 |
Spectral detection of the reaction of formaldehyde with the histidine residues of alpha-chymotrypsin.
Topics: Absorption; Chromatophores; Chymotrypsin; Ethanol; Formaldehyde; Histidine; Hydrogen-Ion Concentration; Imidazoles; Models, Biological; Spectrum Analysis; Water | 1967 |
Aldolase and protease: unsuspected structural homology.
Topics: Amino Acid Sequence; Biological Evolution; Chemical Phenomena; Chemistry; Chymotrypsin; Fructose-Bisphosphate Aldolase; Fungi; Histidine; Peptide Hydrolases; Peptides; Trypsin | 1968 |
The location of the active-site histidine residue in the primary sequence of papain.
Topics: Acetone; Amino Acid Sequence; Binding Sites; Bromine; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Chymotrypsin; Cysteine; Histidine; Methylation; Papain; Peptides; Plants; Protein Hydrolysates; Trypsin | 1968 |
The inhibition of chymotrypsin A4 and B with chloromethyl ketone reagents.
Topics: Alkylating Agents; Binding Sites; Chlorine; Chymotrypsin; Histidine; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Ketones; Methionine | 1968 |
Calf and pea histone IV. I. Amino acid compositions and the identical COOH-terminal 19-residue sequence.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Evolution; Bromine; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Plants; Proline; Serine; Threonine; Trypsin; Tyrosine; Valine | 1968 |
States of amino acid residues in proteins. XVI. Naphthoquinones with two sulfonic groups as a reagent for discrimation of amino groups in proteins.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chymotrypsin; Colorimetry; Freezing; Glycine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Indicators and Reagents; Insulin; Lysine; Muramidase; Naphthoquinones; Proline; Proteins; Ribonucleases; Serine; Spectrophotometry; Sulfonic Acids; Tryptophan; Tyrosine | 1968 |
The reaction of phenylglyoxal with arginine residues in proteins.
Topics: Acetone; Aldehydes; Arginine; Carbon Isotopes; Chemistry, Organic; Chromatography, Gel; Chymotrypsin; Dipeptides; Electrophoresis; Histidine; Hydrogen-Ion Concentration; Iodoacetates; Lysine; Methods; Organic Chemistry Phenomena; Proteins; Ribonucleases; Spectrum Analysis; Trypsin; Ultraviolet Rays | 1968 |
Structure of crystalline -chymotrypsin. II. A preliminary report including a hypothesis for the activation mechanism.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Biochemical Phenomena; Biochemistry; Chymotrypsin; Crystallography; Enzyme Activation; Enzyme Precursors; Histidine; Isoleucine; Mercury; Methionine; Models, Structural; Platinum; Serine; Trypsin | 1968 |
Structure of subtilisin BPN' at 2.5 angström resolution.
Topics: Amino Acid Sequence; Bacteria; Chymotrypsin; Crystallization; Electrons; Endopeptidases; Histidine; Methionine; Models, Structural; Platinum; Serine; Trypsin; X-Ray Diffraction | 1969 |
Role of a buried acid group in the mechanism of action of chymotrypsin.
Topics: Amino Acid Sequence; Aspartic Acid; Bacteria; Binding Sites; Chymotrypsin; Endopeptidases; Histidine; Serine | 1969 |
Identification of histidine in the active center of chymotrypsins from a reptile and a fish.
Topics: Alkylating Agents; Amino Acids; Animals; Autoanalysis; Binding Sites; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chymotrypsin; Fishes; Histidine; Pancreas; Phenylalanine; Species Specificity; Turtles | 1969 |
Structural studies on rabbit muscle glycerol 3-phosphate dehydrogenase and a comparison of chemical and physical determinations of its molecular weight.
Topics: Alkylation; Amino Acids; Animals; Arginine; Autoradiography; Bees; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Gel; Chymotrypsin; Cysteine; Glycerolphosphate Dehydrogenase; Histidine; Isomerases; Kinetics; Lysine; Molecular Weight; Muscles; Rabbits; Rats; Species Specificity; Trypsin; Tryptophan; Tyrosine; Ultracentrifugation | 1969 |
Modification of alpha-chymotrypsin by methyl p-nitrobenzenesulfonate.
Topics: Chemical Phenomena; Chemistry; Chymotrypsin; Histidine; Methylation; Models, Chemical; Nitrobenzenes; Sulfonic Acids | 1969 |
Kinetic properties of the alpha-lytic protease of Sorangium sp., a bacterial homologue of the pancreatopeptidases.
Topics: Acetates; Amino Acid Sequence; Arginine; Bacteria; Catalysis; Chymotrypsin; Deuterium; Electrophoresis; Esters; Histidine; Hydrogen-Ion Concentration; Kinetics; Nitrophenols; Pancreatic Elastase; Peptide Hydrolases; Protease Inhibitors; Protein Binding; Serine; Spectrophotometry; Trypsin; Tryptophan; Tyrosine | 1969 |
Cupric and nickel ion interactions with proteins as studied by circular dichroism.
Topics: Albumins; Chemical Phenomena; Chemistry; Chymotrypsin; Copper; Histidine; Hydrogen-Ion Concentration; Muramidase; Nickel; Ovalbumin; Protein Binding; Proteins; Ribonucleases; Serum Albumin, Bovine; Spectrum Analysis; Sulfhydryl Compounds; Vasopressins | 1969 |
Factors in the iodination of histidine in proteins.
Topics: Alcohol Oxidoreductases; Animals; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Glutamate Dehydrogenase; Guanidines; Histidine; Hydrogen-Ion Concentration; Insulin; Iodine; Iodine Isotopes; Iodoproteins; L-Lactate Dehydrogenase; Lactoglobulins; Male; Muramidase; Phosphoglucomutase; Proteins; Rabbits; Rats; Ribonucleases; Swine; Thyroglobulin; Thyroid Gland; Trypsin | 1969 |
Effect of alkylguanidines on the inactivation of trypsin by alkylation and phosphorylation.
Topics: Acetates; Alkylation; Amides; Amino Acids; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Guanidines; Histidine; Hydrogen-Ion Concentration; Imidazoles; Iodoacetates; Isoflurophate; Kinetics; Methylation; Pancreas; Phosphates; Time Factors; Trypsin | 1969 |
Coupling of p-nitrophenyl diazonium fluoroborate to bovine chymotrypsinogen A and alpha-chymotrypsin.
Topics: Animals; Boron Compounds; Caproates; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Diazonium Compounds; Enzyme Precursors; Fluorine; Histidine; Kinetics; Lysine; Nitrophenols; Spectrum Analysis; Urea | 1969 |
[Structure of peptides isolated from chymotrypsin hydrolysates of horse myoglobin].
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Carboxypeptidases; Chromatography, Gel; Chymotrypsin; Dinitrophenols; Histidine; Horses; Leucyl Aminopeptidase; Methionine; Myoglobin; Peptides; Phenylalanine; Tryptophan; Tyrosine | 1969 |
The iodination of chymotrypsinogen.
Topics: Ammonia; Autoradiography; Chemical Phenomena; Chemistry; Chymotrypsin; Enzyme Precursors; Histidine; In Vitro Techniques; Iodine; Peptides; Tyrosine; Urea | 1964 |
States of amino acid residues in proteins. 8. Tyrosine, histidine and tryptophan residues in chymotrypsin in the presence of substrate and in diisopropylphosphorylchymotrypsin.
Topics: Chemical Phenomena; Chemistry; Chymotrypsin; Glycine; Histidine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Isoflurophate; Tryptophan; Tyrosine | 1965 |
The reaction of phenoxymethyl chloromethyl ketone with nitrogen 3 of histidine-57 of chymotrypsin.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Ketones; Methionine; Nitrogen; Peptides | 1965 |
[Modification of a histidine residue in chymotrypsin by 2-phenyl-1,4-dibromoacetoin].
Topics: Chemical Phenomena; Chemistry; Chymotrypsin; Enzymes; Histidine; Ketones | 1965 |
[Nitrogen-3 of histidine-57 residue in chymotrypsin directly participating in catalysis].
Topics: Chemical Phenomena; Chemistry; Chymotrypsin; Cystine; Enzymes; Histidine | 1965 |
[Alkylation of histidine radicals in the active center of horse myoglobin].
Topics: Acetates; Alkylation; Animals; Chymotrypsin; Histidine; Horses; Hydrogen-Ion Concentration; In Vitro Techniques; Iodoacetates; Myoglobin; Phenylalanine; Protein Denaturation | 1965 |
States of amino acid residues in proteins. VII. Hydrogen bonding of tyrosine residues in the insulin molecule.
Topics: Amino Acid Sequence; Animals; Arginine; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chymotrypsin; Glutamates; Histidine; Hydrogen; In Vitro Techniques; Insulin; Trypsin; Tyrosine | 1965 |
Products from the photolysis of diazoacetyl chymotrypsin.
Topics: Azo Compounds; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chymotrypsin; Glycolates; Histidine; Light; Serine; Tyrosine | 1966 |
The histidyl residues in ribonuclease-S. Photooxidation in solution and in single crystals; the iodination of histidine-12.
Topics: Chemical Phenomena; Chemistry; Chymotrypsin; Crystallography; Histidine; Light; Peptides; Ribonucleases; Solutions; Trypsin; X-Ray Diffraction | 1966 |
Differences in amino acid sequence between sheep haemoglobins A and B.
Topics: Amino Acid Sequence; Animals; Chymotrypsin; Hemoglobins; Histidine; Methionine; Peptides; Sheep | 1966 |
Histidine sequences in the active centres of some 'serine' proteinases.
Topics: Amino Acid Sequence; Animals; Carboxypeptidases; Cattle; Chymotrypsin; Electrophoresis; Enzyme Precursors; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Ketones; Pancreatic Elastase; Peptides; Serine; Swine; Trypsin | 1966 |
[Isolation of a histidine-40 peptide from chymotrypsin inactivated with 1,4-dibromo-2-phenyl-acetoin].
Topics: Alkylating Agents; Chymotrypsin; Enzymes; Histidine; Ketones; Peptides | 1967 |
Studies on the reaction of chymotrypsin and L-1-chloro-3-tosylamido-4-phenyl-2-butanone.
Topics: Amides; Chymotrypsin; Enzymes; Histidine; Hydrogen-Ion Concentration; Kinetics; Protein Binding | 1967 |
Amino acid sequence around the histidine residue of the alpha-lytic protease of Sorangium sp., a bacterial homolog of the pancreatic serine proteases.
Topics: Amino Acid Sequence; Bacteria; Chymotrypsin; Electrophoresis; Histidine; Peptide Hydrolases; Peptides; Serine | 1967 |
Proton magnetic resonance spectroscopy of histidine residues in proteins.
Topics: Animals; Cattle; Cetacea; Chymotrypsin; Cytochromes; Histidine; Horses; Insulin; Magnetic Resonance Spectroscopy; Muramidase; Myoglobin; Proteins; Trypsin; Trypsinogen | 1967 |
High-molecular-weight precursor of epidermal filaggrin and hypothesis for its tandem repeating structure.
Topics: Amino Acid Sequence; Animals; Chymotrypsin; Epidermis; Filaggrin Proteins; Histidine; Intermediate Filament Proteins; Molecular Weight; Protein Precursors; Rats; Rats, Inbred Strains | 1984 |
Interactions between Asp, His, Ser residues within models of the active site of serine proteases. A theoretical empirical study.
Topics: Aspartic Acid; Binding Sites; Chymotrypsin; Dipeptides; Endopeptidases; Histidine; Models, Molecular; Protein Conformation; Serine; Serine Endopeptidases; Structure-Activity Relationship; Subtilisins | 1982 |
Synthesis, conformation and reactivity towards p-nitrophenyl acetate of polypeptides incorporating aspartic acid, serine and histidine.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Chymotrypsin; Circular Dichroism; Histidine; Nitrophenols; Peptides; Protein Conformation; Serine; Spectrophotometry, Infrared; Structure-Activity Relationship; Subtilisins | 1982 |
Changes in pKa values of individual histidine residues of human hemoglobin upon reaction with carbon monoxide.
Topics: Amino Acid Sequence; Binding Sites; Carbon Monoxide; Carboxyhemoglobin; Chymotrypsin; Hemoglobin A; Hemoglobins; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Peptide Fragments; Protein Binding; Trypsin | 1980 |
A low-barrier hydrogen bond in the catalytic triad of serine proteases.
Topics: Aspartic Acid; Catalysis; Chymotrypsin; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Maleates; Malonates; Serine; Serine Endopeptidases; Temperature; Urocanic Acid | 1994 |
Low-barrier hydrogen bonds.
Topics: Aspartic Acid; Chymotrypsin; Histidine; Hydrogen Bonding | 1995 |
Converting tissue plasminogen activator to a zymogen: a regulatory triad of Asp-His-Ser.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Catalysis; Chymotrypsin; Enzyme Precursors; Histidine; Hydrogen Bonding; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasminogen; Plasminogen Activator Inhibitor 1; Serine; Tissue Plasminogen Activator | 1993 |
11B NMR spectroscopy of peptide boronic acid inhibitor complexes of alpha-lytic protease. Direct evidence for tetrahedral boron in both boron-histidine and boron-serine adduct complexes.
Topics: Amino Acid Sequence; Boron; Boronic Acids; Chymotrypsin; Gram-Negative Bacteria; Histidine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligopeptides; Serine; Serine Endopeptidases | 1993 |
Chymotrypsin inhibitory activity of normal C1-inhibitor and a P1 Arg to His mutant: evidence for the presence of overlapping reactive centers.
Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Chymotrypsin; Complement C1 Inactivator Proteins; Histidine; Humans; Molecular Sequence Data; Mutagenesis; Peptide Fragments; Rabbits; Recombinant Proteins; Sequence Analysis; Sequence Homology, Amino Acid | 1993 |
The immobilized porcine pancreatic exopeptidases and its application in casein hydrolysates debittering.
Topics: Ammonium Sulfate; Animals; Arginine; Caseins; Chitin; Chromatography, High Pressure Liquid; Chymotrypsin; Decapoda; Enzymes, Immobilized; Exopeptidases; Glutamine; Glutaral; Histidine; Humans; Hydrolysis; Leucine; Lysine; Pancreas; Peptide Hydrolases; Phenylalanine; Swine; Taste; Trypsin; Tyrosine | 1996 |
Characterization of pNiXa, a serpin of Xenopus laevis oocytes and embryos, and its histidine-rich, Ni(II)-binding domain.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Amino Acid Sequence; Animals; Carrier Proteins; Cattle; Chymotrypsin; Circular Dichroism; Deoxyguanosine; Embryo, Nonmammalian; Endopeptidases; Histidine; Immunoenzyme Techniques; Molecular Sequence Data; Molecular Weight; Nickel; Oocytes; Oxidation-Reduction; Pancreatic Elastase; Protein Binding; Sequence Homology, Amino Acid; Serpins; Spectrophotometry, Ultraviolet; Trypsin Inhibitors; Xenopus laevis; Xenopus Proteins | 1996 |
Residue accessibility, hydrogen bonding, and molecular recognition: metal-chelate probing of active site histidines in chymotrypsins.
Topics: Animals; Binding Sites; Cattle; Chelating Agents; Chromatography, Affinity; Chymotrypsin; Chymotrypsinogen; Copper; Crystallography, X-Ray; Histidine; Hydrogen Bonding; Imino Acids; Models, Molecular; Protein Conformation; Surface Properties | 1997 |
The tortuous story of Asp ... His ... Ser: structural analysis of alpha-chymotrypsin.
Topics: Amino Acid Sequence; Aspartic Acid; Chymotrypsin; Histidine; Protein Structure, Tertiary; Serine | 1997 |
Imprinting of lyophilized alpha-chymotrypsin affects the reactivity of the active-site imidazole.
Topics: Animals; Binding Sites; Catalysis; Cattle; Chymotrypsin; Crystallization; Enzyme Activation; Enzyme Stability; Histidine; Imidazoles; Ligands; Magnetic Resonance Spectroscopy; Vacuum | 1997 |
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A.
Topics: Binding Sites; Chymases; Chymotrypsin; Computer Simulation; Crystallography, X-Ray; Histidine; Humans; Models, Molecular; Phenylmethylsulfonyl Fluoride; Protein Conformation; Serine; Serine Endopeptidases; Substrate Specificity | 1997 |
Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
Topics: Binding Sites; Boronic Acids; Chymotrypsin; Crystallography, X-Ray; Histidine; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Protein Conformation; Serine; Serine Proteinase Inhibitors; Stereoisomerism; Subtilisins | 1998 |
Determination of diethylpyrocarbonate-modified amino acid residues in alpha 1-acid glycoprotein by high-performance liquid chromatography electrospray ionization-mass spectrometry and matrix-assisted laser desorption/ionization time-of-flight-mass spectro
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Chymotrypsin; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Lysine; Molecular Sequence Data; Orosomucoid; Serine Endopeptidases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Trypsin; Tyrosine | 1998 |
Correlations of the basicity of His 57 with transition state analogue binding, substrate reactivity, and the strength of the low-barrier hydrogen bond in chymotrypsin.
Topics: Animals; Asparagine; Binding Sites; Catalysis; Cattle; Chymotrypsin; Dipeptides; Enzyme Activation; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Ketones; Kinetics; Macromolecular Substances; Magnetic Resonance Spectroscopy; Stereoisomerism; Substrate Specificity; Temperature | 1998 |
Effect of exceptional valine replacement for highly conserved alanine-55 on the catalytic site structure of chymotrypsin-like serine protease.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cattle; Chymotrypsin; Histidine; Models, Molecular; Molecular Sequence Data; Protein C; Protein Conformation; Sequence Alignment; Serine; Threonine; Valine | 1998 |
Properties of the His57-Asp102 dyad of rat trypsin D189S in the zymogen, activated enzyme, and alpha1-proteinase inhibitor complexed forms.
Topics: alpha 1-Antitrypsin; Amino Acid Substitution; Animals; Asparagine; Binding Sites; Cattle; Chymotrypsin; Chymotrypsinogen; Enzyme Activation; Enzyme Precursors; Histidine; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Protons; Rats; Temperature; Titrimetry; Trypsin; Trypsinogen | 1999 |
R73A and H144Q mutants of the yeast mitochondrial cyclophilin Cpr3 exhibit a low prolyl isomerase activity in both peptide and protein-folding assays.
Topics: Arginine; Binding Sites; Carrier Proteins; Chromatography; Chymotrypsin; Circular Dichroism; Cyclosporine; Escherichia coli Proteins; Histidine; Humans; Kinetics; Mitochondria; Mutation; Peptidylprolyl Isomerase; Protein Binding; Protein Folding; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Substrate Specificity; Tacrolimus | 1999 |
Structure-function relationship in glycosylated alpha-chymotrypsin as probed by IMAC and IMACE.
Topics: Animals; Caseins; Cattle; Chromatography, Affinity; Chymotrypsin; Electrophoresis, Capillary; Glucosamine; Glycosylation; Histidine; Hydrogen Bonding; Imino Acids; Mass Spectrometry; Metals; Structure-Activity Relationship; Tyrosine | 1999 |
The contribution of residues 192 and 193 to the specificity of snake venom serine proteinases.
Topics: Amino Acid Sequence; Aprotinin; Batroxobin; Chymotrypsin; Crotalid Venoms; Dose-Response Relationship, Drug; Fibrinogen; Glycoproteins; Histidine; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Plasminogen; Plasminogen Activators; Recombinant Proteins; Sequence Homology, Amino Acid; Serine Endopeptidases; Structure-Activity Relationship; Substrate Specificity; Tissue Plasminogen Activator | 2000 |
Expression of chymotrypsin(ogen) in the thioredoxin reductase deficient mutant strain of Escherichia coli AD494(DE3) and purification via a fusion product with a hexahistidine-tail.
Topics: Base Sequence; Chymotrypsin; Chymotrypsinogen; DNA; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genetic Vectors; Histidine; Kinetics; Recombinant Fusion Proteins; Thioredoxin-Disulfide Reductase | 2000 |
The Hemophilus influenzae Hap autotransporter is a chymotrypsin clan serine protease and undergoes autoproteolysis via an intermolecular mechanism.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Outer Membrane Proteins; Binding Sites; Biological Transport; Catalysis; Catalytic Domain; Chymotrypsin; Conserved Sequence; Genetic Techniques; Haemophilus influenzae; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Time Factors | 2001 |
Structure of arterivirus nsp4. The smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole.
Topics: Amino Acid Sequence; Anions; Arterivirus; Aspartic Acid; Binding Sites; Catalytic Domain; Chymotrypsin; Crystallography, X-Ray; Histidine; Models, Genetic; Models, Molecular; Molecular Sequence Data; Open Reading Frames; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases | 2002 |
Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I.
Topics: Alcaligenes; Amino Acid Substitution; Animals; Aspartic Acid; Catalytic Domain; Cattle; Chymotrypsin; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Osmolar Concentration; Serine Endopeptidases; Solvents; Species Specificity; Static Electricity; Trypsin; Tryptophan | 2002 |
The PrP-like protein Doppel binds copper.
Topics: Animals; Binding Sites; Binding, Competitive; Blotting, Western; Carbon; Chymotrypsin; Circular Dichroism; Copper; Diethyl Pyrocarbonate; Dose-Response Relationship, Drug; Free Radicals; GPI-Linked Proteins; Histidine; Kinetics; Mice; Nitrogen; Peptides; Prions; Protein Binding; Proteins; PrPC Proteins; Recombinant Proteins; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 2003 |
[Decomposition of chymotrypsin and chymotrypsin derivatives by diazobenzene-sulfonic acid and characterization of "reactive" histidine residues of the active centers].
Topics: Azo Compounds; Chymotrypsin; Diazonium Compounds; Histidine; Sulfanilic Acids; Sulfonic Acids; Tyrosine | 1962 |
[Inhibition and reactivation of the hydrolases of digestion].
Topics: Alkaline Phosphatase; Amylases; Arginine; Aspartic Acid; Bilirubin; Chymotrypsin; Digestion; Histidine; Humans; Hydrolases; Intestine, Small; Intestines; Oleic Acid; Oleic Acids; Palmitic Acid; Stearic Acids; Trypsin | 1962 |
2-Bnzylhistidine and derivatives as pilots for the synthesis of peptides designed to have specific enzymic activity.
Topics: Chymotrypsin; Histidine; Peptides | 1962 |
Amino acids involved in the action of chymotrypsin.
Topics: Amino Acids; Chymotrypsin; Histidine; Lysine; Methionine; Serine; Tryptophan | 1962 |
STATES OF AMINO ACID RESIDUES IN PROTEINS. 3. HISTIDINE RESIDUES IN INSULIN, LYSOZYME, ALBUMIN AND PROTEINASES AS DETERMINED WITH A NEW REAGENT OF DIAZO-I-H-TETRAZOLE.
Topics: Amino Acids; Animals; Bacitracin; Cattle; Chymotrypsin; Enzyme Precursors; Histidine; Indicators and Reagents; Insulin; Muramidase; Peptide Hydrolases; Proteins; Research; Serum Albumin; Serum Albumin, Bovine; Spectrophotometry; Tetrazolium Salts; Trypsin | 1964 |
THE HISTIDINE RESIDUE INVOLVED IN THE PROTEOLYTIC ACTIVITY OF ALPHA-CHYMOTRYPSIN.
Topics: Chromatography; Chymotrypsin; Histidine; Pepsin A; Protein Hydrolysates | 1964 |
[RADIOACTIVE LABELLING OF CERTAIN AMINO ACIDS IN CATTLE CHYMOTRYPSINOGEN BY BIOSYNTHESIS IN VITRO].
Topics: Amino Acids; Animals; Carbon Isotopes; Cattle; Chymotrypsin; Chymotrypsinogen; Enzyme Precursors; Histidine; In Vitro Techniques; Leucine; Methionine; Radioactivity; Radioisotopes; Radionuclide Imaging; Research | 1964 |
THE IDENTIFICATION OF THE HISTIDINE RESIDUE AT THE ACTIVE CENTER OF CHYMOTRYPSIN.
Topics: Autoanalysis; Catalysis; Chromatography; Chymotrypsin; Electrophoresis; Histidine; Ketones; Peptides; Research | 1965 |
[THE REACTIVITY OF CYCLIC DIPEPTIDES OF HISTIDINE IN RELATION TO ENZYME CATALYSIS].
Topics: Catalysis; Chymotrypsin; Dipeptides; Histidine; Imidazoles; Research | 1964 |
ENZYMATIC HYPOGLYCEMIA IN ALLOXAN DIABETIC RATS.
Topics: Alloxan; Animals; Chymotrypsin; Diabetes Mellitus, Experimental; Histidine; Hypoglycemia; Pharmacology; Rats; Research; Serine; Trypsin | 1965 |
The low barrier hydrogen bond (LBHB) proposal revisited: the case of the Asp... His pair in serine proteases.
Topics: Aspartic Acid; Binding Sites; Catalysis; Chymotrypsin; Histidine; Hydrogen Bonding; Models, Chemical; Models, Molecular; Serine Endopeptidases | 2004 |
Further insights into quinone cofactor biogenesis: probing the role of mauG in methylamine dehydrogenase tryptophan tryptophylquinone formation.
Topics: Amino Acid Sequence; Chymotrypsin; Coenzymes; Cytochrome-c Peroxidase; Electrophoresis, Polyacrylamide Gel; Histidine; Hydrolysis; Indolequinones; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases Acting on CH-NH Group Donors; Paracoccus denitrificans; Protein Processing, Post-Translational; Protein Subunits; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin; Tryptophan; Valine | 2004 |
pH dependence thermal stability of a chymotrypsin inhibitor from Schizolobium parahyba seeds.
Topics: Calorimetry, Differential Scanning; Chymotrypsin; Circular Dichroism; Histidine; Hot Temperature; Hydrogen-Ion Concentration; Plant Proteins; Plants; Protein Denaturation; Protein Folding; Seeds; Spectrometry, Fluorescence; Temperature; Thermodynamics; Ultraviolet Rays | 2005 |
Unusual structural features of the bacteriophage-associated hyaluronate lyase (hylp2).
Topics: Bacteriophages; Binding Sites; Catalytic Domain; Chromatography; Chymotrypsin; Circular Dichroism; Cross-Linking Reagents; Dimerization; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutaral; Glycosaminoglycans; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Weight; Plasmids; Polysaccharide-Lyases; Protein Conformation; Protein Denaturation; Protein Structure, Tertiary; Recombinant Proteins; Serine; Spectrometry, Mass, Electrospray Ionization; Streptococcus pyogenes; Substrate Specificity; Tryptophan | 2006 |
Developments in the characterisation of the catalytic triad of alpha-chymotrypsin: Effect of the protonation state of Asp102 on the 1H NMR signals of His57.
Topics: Animals; Aspartic Acid; Biochemistry; Catalytic Domain; Cattle; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Pancreas; Protein Conformation; Protons | 2007 |
13C and 1H NMR studies of ionizations and hydrogen bonding in chymotrypsin-glyoxal inhibitor complexes.
Topics: Animals; Binding Sites; Catalysis; Cattle; Chymotrypsin; Glyoxal; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Ions; Magnetic Resonance Spectroscopy; Serine; Surface Plasmon Resonance; Temperature | 2007 |
The cooperative effect between active site ionized groups and water desolvation controls the alteration of acid/base catalysis in serine proteases.
Topics: Binding Sites; Catalysis; Catalytic Domain; Chymotrypsin; Histidine; Serine Proteases; Water | 2007 |
Screening of the active site from water by the incoming ligand triggers catalysis and inhibition in serine proteases.
Topics: Binding Sites; Catalysis; Catalytic Domain; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; Ligands; Serine Endopeptidases; Serine Proteinase Inhibitors; Water | 2008 |
Structural and functional characterization of SplA, an exclusively specific protease of Staphylococcus aureus.
Topics: Amino Acid Sequence; Animals; Anions; Bacterial Proteins; Biocatalysis; Chymotrypsin; Crystallography, X-Ray; Histidine; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Recombinant Proteins; Serine Endopeptidases; Staphylococcus aureus; Substrate Specificity | 2009 |
Analysis of interactions of brevetoxin-B and human serum albumin by liquid chromatography/mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Chymotrypsin; Cysteine; Dinoflagellida; Histidine; Humans; Marine Toxins; Mass Spectrometry; Oxocins; Pronase; Protein Binding; Serum Albumin; Trypsin | 2011 |
Peptide-controlled access to the interior surface of empty virus nanoparticles.
Topics: Capsid Proteins; Chymotrypsin; Cobalt; Comovirus; Histidine; Nanoparticles; Oligopeptides; Peptides | 2011 |
Hemiacetal stabilization in a chymotrypsin inhibitor complex and the reactivity of the hydroxyl group of the catalytic serine residue of chymotrypsin.
Topics: Animals; Biocatalysis; Catalytic Domain; Cattle; Chymotrypsin; Glyoxal; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Protease Inhibitors; Serine; Solutions; Stereoisomerism; Thermodynamics | 2014 |
Mercury(II) binds to both of chymotrypsin's histidines, causing inhibition followed by irreversible denaturation/aggregation.
Topics: Chymotrypsin; Histidine; Mercury; Protein Aggregates; Protein Denaturation; Serine Proteinase Inhibitors | 2017 |
Exfoliated Nanosheets of a Cu
Topics: Animals; Binding Sites; Catalysis; Cell Survival; Chymotrypsin; Coordination Complexes; Copper; Histidine; Kinetics; Mice; Models, Molecular; Nanostructures; Osmolar Concentration; Phenylalanine; Phthalic Acids; Polymers; Protein Conformation; RAW 264.7 Cells | 2018 |