histaprodifen and imidazole

histaprodifen has been researched along with imidazole* in 1 studies

Reviews

1 review(s) available for histaprodifen and imidazole

Article	Year
Structure-activity relationships of histamine H1-receptor agonists. Mini reviews in medicinal chemistry, 2004, Volume: 4, Issue:9 Significant progress in the development of potent and selective histamine H1-receptor agonists has been achieved since 1990. Optimisation of the class of 2-phenylhistamines has furnished 2-[3-(trifluoromethyl)phenyl]histamine and its Nalpha-methyl derivative. The discovery of histaprodifen (2-[2-(3,3-diphenylpropyl)-1H-imidazol-4-yl]ethanamine) and the novel lead compound suprahistaprodifen (Nalpha-2-[(1H-imidazol-4-yl)ethyl]histaprodifen) represents additional milestones in the H1-receptor agonist field. Topics: Animals; Histamine; Histamine Agonists; Humans; Imidazoles; Methylhistamines; Structure-Activity Relationship	2004

Article

Year

Structure-activity relationships of histamine H1-receptor agonists.

Mini reviews in medicinal chemistry, 2004, Volume: 4, Issue:9

Significant progress in the development of potent and selective histamine H1-receptor agonists has been achieved since 1990. Optimisation of the class of 2-phenylhistamines has furnished 2-[3-(trifluoromethyl)phenyl]histamine and its Nalpha-methyl derivative. The discovery of histaprodifen (2-[2-(3,3-diphenylpropyl)-1H-imidazol-4-yl]ethanamine) and the novel lead compound suprahistaprodifen (Nalpha-2-[(1H-imidazol-4-yl)ethyl]histaprodifen) represents additional milestones in the H1-receptor agonist field.

Topics: Animals; Histamine; Histamine Agonists; Humans; Imidazoles; Methylhistamines; Structure-Activity Relationship

2004