histamine and rolipram

histamine has been researched along with rolipram in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.53)18.7374
1990's14 (36.84)18.2507
2000's14 (36.84)29.6817
2010's5 (13.16)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Ainz, LF; Carou, M; Gáldiz, B; Gandarias, JM; Gil-Rodrigo, CE; Gómez, R; Vallejo, A1
Brown, AM; Hill, SJ; Stanley, C1
Donaldson, J; Hall, IP; Hill, SJ1
Brown, AM; Donaldson, J; Hill, SJ1
Lohse, MJ; Puurunen, J; Schwabe, U1
Meurs, H; Olymulder, CG; Santing, RE; Van der Molen, K; Zaagsma, J1
Barnette, MS; Burman, M; Christensen, SB; Cieslinski, LB; Grous, M; Torphy, TJ1
Battram, CH; Jordan, R; Lewis, SA; Raeburn, D; Sharma, S; Souness, JE; Tomkinson, A; Underwood, SL; Webber, SE; Woodman, VR1
Bou, J; Cortijo, J; Morcillo, EJ; Ortiz, JL; Vallés, JM1
Ellis, JL; Fernandes, LB; Undem, BJ1
Newsholme, SJ; Schwartz, L1
Daykin, K; Hall, IP; Widdop, S1
Cortijo, J; Martí-Cabrera, M; Morcillo, EJ; Ortiz, JL; Vallés, JM1
Blake, SM; Gozzard, N; Herd, CM; Higgs, GA; Holbrook, M; Hughes, B; Page, CP1
Dahl, SG; Lagente, V; Payne, AN; Planquois, JM; Ruffin-Morin, Y1
Cantabrana, B; Hidalgo, A; Perez-Vallina, JR; Revuelta, MP1
Dahl, R; Nielsen-Kudsk, F; Thirstrup, S1
Ikezawa, K; Kaminuma, O; Kikkawa, H; Oka, K; Sugaya, T; Wada, K; Yamagata, S1
Blandizzi, C; Colucci, R; Del Tacca, M; Tognetti, M1
Branscheid, D; Dent, G; Magnussen, H; Rabe, KF; Rühlmann, E; Schmidt, DT; Watson, N1
Ezeamuzie, CI1
Dorovini-Zis, K; Easton, AS1
Bessard, G; Bréant, D; Caron, F; Corompt, E; Devillier, P1
Delgado, M; Fernandez-Alfonso, MS; Fuentes, JA1
Broadley, KJ; Toward, TJ1
Sadan, G; Tuncel, B; Usta, C1
Kam, MF; Lau, HY1
Beanlands, RS; DaSilva, JN; Kenk, M; Lourenco, CM1
Chazan, R; Glapiński, J; Grubek-Jaworska, H; Hoser, G; Nejman-Gryz, P1
Alvarez, E; Cairrão, E; Morgado, M; Santos-Silva, AJ; Verde, I1
Campos-Toimil, M; Keravis, T; Lugnier, C; Orallo, F; Takeda, K1
Aihara, E; Honda, M; Ito, Y; Kato, S; Mitsufuji, S; Okuda, S; Takeuchi, K; Yoshikawa, T1
Albadine, R; Lugnier, C; Morin, C; Rousseau, E; Senouvo, FY; Sirois, C; Yougbare, I1
Fisher, MJ; Liu, S; Paganini-Hill, A; Yang, F; Yu, C1
Christensen, I; Joskova, M; Mokra, D; Mokry, J; Nosalova, G1
Hong, JH; Lee, DU; Shin, DM1
Gergs, U; Laufs, U; Neumann, J; Voss, R; Werner, C1

Other Studies

38 other study(ies) available for histamine and rolipram

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
[Specific inhibition by ATP of histamine-stimulated acid secretion in the gastric glands of the rabbit].
    Revista espanola de fisiologia, 1992, Volume: 48, Issue:1

    Topics: Adenosine Triphosphate; Animals; Bucladesine; Carbachol; Depression, Chemical; Female; Gastric Acid; Gastric Mucosa; Histamine; Histamine Antagonists; Indomethacin; Male; Prostaglandins; Pyrrolidinones; Rabbits; Rolipram; Secretory Rate; Theophylline

1992
Effect of isozyme-selective inhibitors of phosphodiesterase on histamine-stimulated cyclic AMP accumulation in guinea-pig hippocampus.
    Journal of neurochemistry, 1989, Volume: 52, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cerebral Cortex; Cyclic AMP; Female; Guinea Pigs; Hippocampus; Histamine; Isoenzymes; Male; Purinones; Pyrazines; Pyrrolidinones; Rolipram

1989
Inhibition of histamine-stimulated inositol phospholipid hydrolysis by agents which increase cyclic AMP levels in bovine tracheal smooth muscle.
    British journal of pharmacology, 1989, Volume: 97, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Albuterol; Animals; Bucladesine; Cattle; Colforsin; Cyclic AMP; Histamine; Histamine Antagonists; Hydrolysis; In Vitro Techniques; Inositol Phosphates; Muscle, Smooth; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Sugar Phosphates; Trachea; Vasoactive Intestinal Peptide

1989
Influence of rolipram on the cyclic 3',5'-adenosine monophosphate response to histamine and adenosine in slices of guinea-pig cerebral cortex.
    Biochemical pharmacology, 1988, Feb-15, Volume: 37, Issue:4

    Topics: 2-Chloroadenosine; Adenosine; Animals; Cerebral Cortex; Cyclic AMP; Female; Guinea Pigs; Histamine; In Vitro Techniques; Kinetics; Male; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram

1988
Interactions between intracellular cyclic AMP and agonist-induced inositol phospholipid breakdown in isolated gastric mucosal cells of the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:5

    Topics: Animals; Bucladesine; Carbachol; Cimetidine; Colforsin; Cyclic AMP; Dibutyryl Cyclic GMP; Enzyme Activation; Histamine; In Vitro Techniques; Inositol Phosphates; Male; Parietal Cells, Gastric; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Pyrrolidinones; Rats; Rats, Inbred Strains; Rolipram; Sugar Phosphates

1987
Phosphodiesterase inhibitors reduce bronchial hyperreactivity and airway inflammation in unrestrained guinea pigs.
    European journal of pharmacology, 1995, Feb-24, Volume: 275, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Inhalation; Analysis of Variance; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Eosinophils; Guinea Pigs; Histamine; Hypersensitivity; Inflammation; Injections, Intraperitoneal; Isoenzymes; Macrophages; Male; Neutrophils; Ovalbumin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Rolipram; Specific Pathogen-Free Organisms; Theophylline; Thiazoles

1995
Inhibitors of phosphodiesterase IV (PDE IV) increase acid secretion in rabbit isolated gastric glands: correlation between function and interaction with a high-affinity rolipram binding site.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyrine; Animals; Binding Sites; Bucladesine; Cyclic Nucleotide Phosphodiesterases, Type 4; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Rabbits; Rolipram

1995
Anti-inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitor.
    British journal of pharmacology, 1994, Volume: 113, Issue:4

    Topics: Albuterol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Bronchial Hyperreactivity; Bronchial Spasm; Bronchodilator Agents; Capillary Permeability; Guinea Pigs; Hemodynamics; Histamine; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Platelet Activating Factor; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram

1994
Rolipram inhibits airway microvascular leakage induced by platelet-activating factor, histamine and bradykinin in guinea-pigs.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:12

    Topics: Aminophylline; Animals; Blood Pressure; Bradykinin; Bronchi; Capillary Permeability; Drug Interactions; Evans Blue; Guinea Pigs; Histamine; Microcirculation; Phosphodiesterase Inhibitors; Platelet Activating Factor; Pyrrolidinones; Rolipram; Trachea

1993
Potentiation of nonadrenergic noncholinergic relaxation of human isolated bronchus by selective inhibitors of phosphodiesterase isozymes.
    American journal of respiratory and critical care medicine, 1994, Volume: 150, Issue:5 Pt 1

    Topics: Atropine; Bronchi; Colforsin; Electric Stimulation; Histamine; Humans; In Vitro Techniques; Indomethacin; Isoenzymes; Molsidomine; Muscle Relaxation; Nitroprusside; Phosphodiesterase Inhibitors; Propranolol; Purinones; Pyrrolidinones; Rolipram

1994
cAMP-specific phosphodiesterase inhibitor, rolipram, reduces eosinophil infiltration evoked by leukotrienes or by histamine in guinea pig conjunctiva.
    Inflammation, 1993, Volume: 17, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Asthma; Conjunctiva; Conjunctivitis; Eosinophilia; Eosinophils; Guinea Pigs; Histamine; Isoenzymes; Leukotrienes; Male; Pyrrolidinones; Rolipram

1993
Control of histamine induced inositol phospholipid hydrolysis in cultured human tracheal smooth muscle cells.
    European journal of pharmacology, 1993, Jul-15, Volume: 246, Issue:2

    Topics: Cells, Cultured; Cyclic AMP; Histamine; Histamine Agonists; Humans; Hydrolysis; Inositol Phosphates; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Histamine H1; Rolipram; Trachea

1993
Effects of selective phosphodiesterase inhibitors on platelet-activating factor- and antigen-induced airway hyperreactivity, eosinophil accumulation, and microvascular leakage in guinea pigs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:2

    Topics: Animals; Asthma; Dose-Response Relationship, Drug; Eosinophils; Guinea Pigs; Histamine; Male; Phosphodiesterase Inhibitors; Platelet Activating Factor; Pyrrolidinones; Respiratory System; Rolipram

1996
Effects of theophylline and rolipram on antigen-induced airway responses in neonatally immunized rabbits.
    British journal of pharmacology, 1996, Volume: 117, Issue:7

    Topics: Airway Resistance; Alternaria; Animals; Anti-Inflammatory Agents; Antigens, Fungal; Asthma; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Female; Histamine; Leukocyte Count; Lung Compliance; Male; Phosphodiesterase Inhibitors; Pyrrolidinones; Rabbits; Respiratory Hypersensitivity; Rolipram; Theophylline

1996
Salbutamol potentiates the relaxant effects of selective phosphodiesterase inhibitors on guinea pig isolated trachea.
    Fundamental & clinical pharmacology, 1996, Volume: 10, Issue:4

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonists; Albuterol; Animals; Drug Synergism; Guanidines; Guinea Pigs; Histamine; In Vitro Techniques; Male; Milrinone; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Osmolar Concentration; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyridones; Pyrrolidinones; Rolipram; Theophylline; Trachea

1996
Effect of Rp diastereoisomer of adenosine 3',5' cyclic-monophosphothioate on the cAMP-dependent relaxation of smooth muscle.
    Life sciences, 1997, Volume: 61, Issue:9

    Topics: Animals; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Inhibitors; Female; Histamine; Muscle Relaxation; Papaverine; Phosphodiesterase Inhibitors; Potassium Chloride; Pyrrolidinones; Rats; Rats, Wistar; Rolipram; Stereoisomerism; Thionucleotides; Uterine Contraction; Uterus; Vanadates; Vinca Alkaloids

1997
Interaction between prostaglandins and selective phosphodiesterase inhibitors in isolated guinea-pig trachea in vitro.
    European journal of pharmacology, 1997, Aug-27, Volume: 333, Issue:2-3

    Topics: Animals; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Drug Interactions; Female; Guanidines; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Oxytocics; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyrrolidinones; Rolipram; Trachea

1997
Bronchial anti-spasmogenic effects and selectivity of T-440, phosphodiesterase type 4 inhibitor, in the dog.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:12

    Topics: Animals; Blood Pressure; Bronchial Spasm; Bronchoconstriction; Chromatography, High Pressure Liquid; Dogs; Female; Guinea Pigs; Heart Rate; Hemodynamics; Histamine; Isoenzymes; Male; Naphthalenes; Parasympatholytics; Phosphodiesterase Inhibitors; Pyridones; Pyrrolidinones; Rolipram; Theophylline

1997
Histamine H(3) receptors mediate inhibition of noradrenaline release from intestinal sympathetic nerves.
    British journal of pharmacology, 2000, Volume: 129, Issue:7

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Adrenergic alpha-Antagonists; Animals; Calcium; Colforsin; Dose-Response Relationship, Drug; Ethylmaleimide; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Ileum; In Vitro Techniques; Intestinal Mucosa; Intestines; Male; Muscle, Smooth; Myenteric Plexus; Nifedipine; Norepinephrine; omega-Conotoxins; Pertussis Toxin; Phenols; Receptors, Histamine H3; Rolipram; Sympathetic Nervous System; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetrodotoxin; Virulence Factors, Bordetella; Yohimbine

2000
The effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C(4)-induced contractions in passively sensitized human airways.
    British journal of pharmacology, 2000, Volume: 131, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Antigens, Dermatophagoides; Benzamides; Bronchi; Bronchodilator Agents; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Glycoproteins; Histamine; Humans; In Vitro Techniques; Leukotriene C4; Lung Neoplasms; Muscle Contraction; Phosphodiesterase Inhibitors; Pyridazines; Pyridines; Rolipram; Theophylline

2000
Requirement of additional adenylate cyclase activation for the inhibition of human eosinophil degranulation by phosphodiesterase IV inhibitors.
    European journal of pharmacology, 2001, Apr-06, Volume: 417, Issue:1-2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adult; Albuterol; Benzamides; Cell Degranulation; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Eosinophil Peroxidase; Eosinophils; Histamine; Humans; Nitriles; Peroxidases; Phosphodiesterase Inhibitors; Pyridines; Rolipram; Superoxides; Theophylline

2001
The kinetics, function, and regulation of P-selectin expressed by human brain microvessel endothelial cells in primary culture.
    Microvascular research, 2001, Volume: 62, Issue:3

    Topics: Brain; Cell Adhesion; Cells, Cultured; Cimetidine; Edetic Acid; Endothelium, Vascular; Histamine; Humans; Immunohistochemistry; Kinetics; Leukocytes, Mononuclear; Microscopy, Immunoelectron; P-Selectin; Rolipram; Thrombin; Time Factors

2001
Relaxation and modulation of cyclic AMP production in response to atrial natriuretic peptides in guinea pig tracheal smooth muscle.
    European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3

    Topics: Adenylyl Cyclases; Animals; Apamin; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Natriuretic Peptide, C-Type; Nitroprusside; Oxadiazoles; Peptide Fragments; Peptides; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Quinoxalines; Rolipram; Trachea

2001
Histamine up-regulates phosphodiesterase IV activity in U-937 cells through H2 receptor stimulation and cAMP increase.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Diphenhydramine; Guanidines; Histamine; Humans; Kinetics; Purinones; Pyridazines; Ranitidine; Receptors, Histamine H2; Rolipram; U937 Cells

2003
Early and late bronchoconstrictions, airway hyper-reactivity, leucocyte influx and lung histamine and nitric oxide after inhaled antigen: effects of dexamethasone and rolipram.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:1

    Topics: Administration, Inhalation; Animals; Antigens; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dexamethasone; Glucocorticoids; Guinea Pigs; Histamine; Leukocytes; Male; Models, Animal; Nitric Oxide; Rolipram

2004
The effect of the indomethacin on phosphodiesterase inhibitors mediated responses in isolated trachea preparations.
    Prostaglandins, leukotrienes, and essential fatty acids, 2004, Volume: 71, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Isoenzymes; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Ovalbumin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rolipram; Theophylline; Trachea

2004
Inhibition of mast cell histamine release by specific phosphodiesterase inhibitors.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2005, Volume: 54 Suppl 1

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Guanidines; Histamine; Mast Cells; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Isoforms; Pyridazines; Rats; Rats, Sprague-Dawley; Rolipram

2005
Increasing synaptic noradrenaline, serotonin and histamine enhances in vivo binding of phosphodiesterase-4 inhibitor (R)-[11C]rolipram in rat brain, lung and heart.
    Life sciences, 2006, Jun-20, Volume: 79, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Brain; Cyclic Nucleotide Phosphodiesterases, Type 4; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Heart; Histamine; Lung; Male; Myocardium; Neurotransmitter Agents; Norepinephrine; Phosphodiesterase Inhibitors; Piperidines; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; Rolipram; Selective Serotonin Reuptake Inhibitors; Serotonin; Synapses; Tranylcypromine

2006
Effects of the phosphodiestrase-4 inhibitor rolipram on lung resistance and inflammatory reaction in experimental asthma.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57 Suppl 4

    Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Dexamethasone; Guinea Pigs; Histamine; Inflammation; Leukocyte Count; Lung; Male; Ovalbumin; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Rolipram

2006
PDE4 and PDE5 regulate cyclic nucleotides relaxing effects in human umbilical arteries.
    European journal of pharmacology, 2008, Mar-17, Volume: 582, Issue:1-3

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 5; Dipyridamole; Female; Guanylate Cyclase; Histamine; Humans; In Vitro Techniques; Isoenzymes; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthyridines; Nitroprusside; Phosphodiesterase 4 Inhibitors; Phosphodiesterase 5 Inhibitors; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Rolipram; Serotonin; Umbilical Arteries; Vasodilator Agents

2008
Short-term or long-term treatments with a phosphodiesterase-4 (PDE4) inhibitor result in opposing agonist-induced Ca(2+) responses in endothelial cells.
    British journal of pharmacology, 2008, Volume: 154, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Blotting, Northern; Blotting, Western; Bucladesine; Calcium; Calcium Signaling; Cell Line; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cycloheximide; Data Interpretation, Statistical; Endothelial Cells; Fluorescent Dyes; Fura-2; Histamine; Humans; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Protein Synthesis Inhibitors; Rolipram

2008
Phosphodiesterase isozymes involved in regulating acid secretion in the isolated mouse stomach.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009, Volume: 60 Suppl 7

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastric Mucosa; Histamine; Histamine Agonists; Histamine Antagonists; Histamine Release; In Vitro Techniques; Isoenzymes; Male; Mice; Organ Specificity; Perfusion; Phosphodiesterase Inhibitors; Pituitary Adenylate Cyclase-Activating Polypeptide; Rolipram; Stomach; Time Factors

2009
NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues.
    American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 301, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anti-Inflammatory Agents; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Cell Fractionation; Cell Separation; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Histamine; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Isoenzymes; Methacholine Chloride; Middle Aged; Muscle Proteins; Myosin-Light-Chain Phosphatase; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase 4 Inhibitors; Phosphoprotein Phosphatases; Pneumonia; Rolipram; Tissue Culture Techniques; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents

2011
Phosphodiesterase inhibitor modulation of brain microvascular endothelial cell barrier properties.
    Journal of the neurological sciences, 2012, Sep-15, Volume: 320, Issue:1-2

    Topics: Actins; Brain; Capillary Permeability; Carbazoles; Cells, Cultured; Cilostazol; Claudin-5; Dipyridamole; Drug Interactions; Electric Impedance; Endothelial Cells; Histamine; Humans; Isoquinolines; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Pyrroles; Rolipram; Sulfonamides; Tetrazoles

2012
Effects of selective inhibition of PDE4 and PDE7 on airway reactivity and cough in healthy and ovalbumin-sensitized guinea pigs.
    Advances in experimental medicine and biology, 2013, Volume: 756

    Topics: Acetylcholine; Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchoconstriction; Citric Acid; Cough; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 7; Guinea Pigs; Histamine; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; Phosphodiesterase 4 Inhibitors; Plethysmography, Whole Body; Respiratory System; Rolipram

2013
The Regulatory Role of Rolipram on Inflammatory Mediators and Cholinergic/Adrenergic Stimulation-Induced Signals in Isolated Primary Mouse Submandibular Gland Cells.
    Mediators of inflammation, 2016, Volume: 2016

    Topics: Animals; Calcium Signaling; Cells, Cultured; Histamine; Inflammation; Lipopolysaccharides; Mice; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Rolipram; Signal Transduction; Submandibular Gland

2016
Phosphodiesterases 2, 3 and 4 can decrease cardiac effects of H
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:6

    Topics: Adenine; Animals; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Female; Heart Atria; Heart Rate; Histamine; Humans; Male; Mice; Mice, Transgenic; Phosphodiesterase Inhibitors; Quinolones; Receptors, Histamine H2; Rolipram

2021