histamine has been researched along with pyrimidinones in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (53.57) | 18.7374 |
| 1990's | 9 (32.14) | 18.2507 |
| 2000's | 2 (7.14) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bando, T; Fujimura, M; Matsuda, T; Mizuhashi, K | 1 |
| Franzén, L; Ghassemifar, R; Malcherek, P | 1 |
| Holzer, P; Lippe, IT | 1 |
| Atterwill, CK; Catto, LC; Conybeare, G; Jones, CA; Mortensen, A | 1 |
| Batzri, S; Thompson, WF; Toles, R | 1 |
| Bodéré, H; Emami, S; Gespach, C | 1 |
| Araujo, OE; Flowers, FP; Nieves, CH | 1 |
| Emami, S; Gespach, C | 1 |
| Malo, PE; Muccitelli, R; Tucker, SS; Wasserman, MA | 1 |
| Knigge, U; Matzen, S; Warberg, J | 2 |
| Brown, EA; Griffiths, R; Harvey, CA; Owen, DA | 1 |
| Marks, R; Shall, L | 1 |
| Batzri, S; Harmon, JW; Toles, R | 1 |
| Badger, AM; Poste, G; Young, J | 1 |
| Dungan, KW; Gillespie, E | 1 |
| Falck, P; Schnitzler, S; Volk, D | 1 |
| Bristow, DR; Dupere, JR; Zamani, MR | 1 |
| Fujihara, A; Kamato, T; Miyata, K; Nishida, A; Takeda, M; Yuki, H | 1 |
| Hough, LB; Mischler, SA; Nalwalk, JW; Thoburn, KK | 1 |
| Ikarashi, Y; Kawano, O; Misaki, N; Ohba, S; Uchida, M | 1 |
| Bach, FW; Kjaer, A; Knigge, U; Madsen, EL; Søe-Jensen, P; Warberg, J | 1 |
| Corbel, S; Dy, M | 1 |
| Cheng, JB; Cohan, VL; Pazoles, CJ; Showell, HJ; Turner, CR; Watson, JW | 1 |
| Rathod, IS; Shirsath, VS; Shishoo, CJ; Yande, VD | 1 |
| Christensen, GP; Forte, JG; Ghayouri, S; Mettler, SE | 1 |
| Denisenko, VA; Santalova, EA; Stonik, VA | 1 |
| McCoy, ES; Pribisko, AL; Street, SE; Taylor-Blake, B; Zheng, J; Zylka, MJ | 1 |
1 review(s) available for histamine and pyrimidinones
| Article | Year |
|---|---|
Antihistamines.
Topics: Animals; Astemizole; Benzhydryl Compounds; Benzimidazoles; Child; Child, Preschool; Cimetidine; Drug Synergism; Guanidines; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Infant; Infant, Newborn; Kinetics; Pyrimidinones; Ranitidine; Terfenadine | 1986 |
1 trial(s) available for histamine and pyrimidinones
| Article | Year |
|---|---|
Non-invasive instrumental techniques to detect terfenadine and temelastine induced suppression of histamine weals in man.
Topics: Adolescent; Adult; Benzhydryl Compounds; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Pyrimidinones; Random Allocation; Regional Blood Flow; Skin; Skin Tests; Terfenadine | 1987 |
26 other study(ies) available for histamine and pyrimidinones
| Article | Year |
|---|---|
Interaction of thromboxane A2 and leukotrienes in guinea pig airways in vivo.
Topics: Administration, Inhalation; Animals; Asthma; Bridged Bicyclo Compounds; Bronchoconstriction; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Male; Pyridines; Pyrimidines; Pyrimidinones; Receptors, Immunologic; Receptors, Leukotriene; Receptors, Prostaglandin; Receptors, Thromboxane; SRS-A; Tetrazoles; Thromboxane A2 | 1991 |
Experimental mast cell activation improves connective tissue repair in the perforated rat mesentery.
Topics: Animals; Connective Tissue; Histamine; Histamine H2 Antagonists; Male; Mast Cells; Mesentery; p-Methoxy-N-methylphenethylamine; Pyrimidinones; Rats; Rats, Inbred Strains; Wound Healing | 1991 |
The diacylglycerol kinase inhibitor, R 59022, suppresses contractility of intestinal smooth muscle.
Topics: Acetylcholine; Animals; Calcium; Diacylglycerol Kinase; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Phosphotransferases; Platelet Activating Factor; Pyrimidinones; Substance P; Thiazoles | 1989 |
SK&F 93574, a histamine H2-receptor antagonist, releases histamine in the dog.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Histamine; Histamine H2 Antagonists; Histamine Release; Pyrimidinones; Radioimmunoassay | 1989 |
Distortion of H2-antagonist equilibrium constants by uptake in rabbit gastric mucosal cells.
Topics: Aminopyrine; Animals; Cimetidine; Cyclic AMP; Dimaprit; Gastric Acid; Gastric Mucosa; Guanidines; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Pyrimidinones; Rabbits; Radioisotopes; Rubidium; Thiadiazoles; Thiourea | 1985 |
Selective disappearance of histamine H2-receptor activity in the human gastric cancer cell line HGT-1 after short-term or chronic treatment by histamine or its H2-antagonists.
Topics: Cell Line; Cimetidine; Histamine; Histamine H2 Antagonists; Humans; Pyrimidinones; Receptors, Histamine; Receptors, Histamine H2; Stomach Neoplasms; Vasoactive Intestinal Peptide | 1985 |
Pharmacology of histamine H2 receptor antagonists in the human gastric cancer cell line HGT-1. Structure-activity relationship of isocytosine-furan and imidazole derivatives related to cimetidine.
Topics: Cell Line; Cimetidine; Cyclic AMP; Histamine; Histamine H2 Antagonists; Humans; Kinetics; Pyrimidinones; Receptors, Cell Surface; Receptors, Histamine; Receptors, Histamine H2; Receptors, Vasoactive Intestinal Peptide; Stomach Neoplasms; Structure-Activity Relationship; Vasoactive Intestinal Peptide | 1986 |
Effects of SK&F 93944 (Temelastine), a potent histamine H1-receptor antagonist in pharmacologic and antigen-induced bronchoconstriction.
Topics: Animals; Antigens; Bronchi; Dogs; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Ovalbumin; Pyrilamine; Pyrimidinones; Trachea | 1986 |
Histaminergic stimulation of prolactin secretion mediated via H1- or H2-receptors: dependence on routes of administration.
Topics: Animals; Cimetidine; Dimaprit; Histamine; Histamine H1 Antagonists; Male; Methylhistamines; Pituitary Gland, Anterior; Prolactin; Pyrilamine; Pyrimidinones; Rats; Receptors, Histamine; Thiazoles; Thiourea | 1986 |
Pharmacological studies with SK&F 93944 (temelastine), a novel histamine H1-receptor antagonist with negligible ability to penetrate the central nervous system.
Topics: Animals; Autonomic Nervous System; Central Nervous System; Cerebrovascular Circulation; Female; Guinea Pigs; Hemodynamics; Histamine; Histamine H1 Antagonists; Male; Parasympatholytics; Pyrilamine; Pyrimidinones; Skin Absorption; Sympathetic Nervous System | 1986 |
Histaminergic mediation of the stress-induced release of prolactin in male rats.
Topics: Animals; Cimetidine; Ether; Histamine; Injections, Intravenous; Injections, Intraventricular; Male; Prolactin; Pyrilamine; Pyrimidinones; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Histamine; Restraint, Physical; Stress, Physiological | 1988 |
Comparison of cimetidine with new H2-antagonists in rabbit and guinea pig gastric cells.
Topics: Aminopyrine; Animals; Cimetidine; Cyclic AMP; Gastric Acid; Gastric Mucosa; Guanidines; Guinea Pigs; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Male; Pyrimidinones; Rabbits; Thiadiazoles | 1983 |
Reversal of histamine-mediated immunosuppression by structurally diverse histamine type II (H2) receptor antagonists.
Topics: Animals; Cells, Cultured; Chemical Phenomena; Chemistry; Cimetidine; Histamine; Histamine H2 Antagonists; Immune Tolerance; Lymphocytes; Mitogens; Monocytes; Pyrimidinones; Ranitidine | 1984 |
Pharmacological properties of BL-5255Z, an antiallergy compound that blocks SRS activity.
Topics: Animals; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Male; Muscle Contraction; Pyrimidinones; SRS-A | 1983 |
Histamine and immune reactions. 3. Inhibition of early events of human lymphocyte activation by histamine.
Topics: Concanavalin A; Histamine; Humans; In Vitro Techniques; Lymphocyte Activation; Pyrimidinones | 1983 |
An immortalised murine hypothalamic neuronal cell, GT1-7, expresses functional histamine H1 receptors.
Topics: Animals; Carbachol; Cell Line, Transformed; Dose-Response Relationship, Drug; Glutamic Acid; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Hypothalamus; Inositol Phosphates; Kinetics; Mice; Neurons; Neuropeptide Y; Piperidines; Pyrimidinones; Ranitidine; Receptors, Histamine H1; Serotonin; Substance P; Tritium | 1994 |
Antisecretory effects of a novel and long-lasting histamine H2-receptor antagonist, YM-14471, in rats and dogs.
Topics: Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Histamine H2 Antagonists; Infusions, Intravenous; Male; Omeprazole; Pyrimidinones; Rats; Rats, Wistar; Thiazoles | 1993 |
Histamine-induced modulation of nociceptive responses.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Mesencephalon; Microinjections; Naloxone; Nociceptors; Pain Measurement; Periaqueductal Gray; Pyrimidinones; Raphe Nuclei; Rats; Rats, Sprague-Dawley | 1994 |
Effect of the novel histamine H2-antagonist 5,6-dimethyl-2-[4-[3-(1- piperidinomethyl)phenoxy]-(z)-2-butenylamino]-4(1H)-pyrimidine dihydrochloride on histamine-induced gastric acid secretion in Heidenhain pouch dogs.
Topics: Administration, Oral; Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Injections, Intravenous; Male; Piperidines; Pyrimidinones | 1993 |
Insulin/hypoglycemia-induced adrenocorticotropin and beta-endorphin release: involvement of hypothalamic histaminergic neurons.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Cetirizine; Cimetidine; Histamine; Histamine Agonists; Histamine Antagonists; Hypoglycemia; Hypothalamus; Insulin; Male; Methylhistamines; Neurons; Pyrilamine; Pyrimidinones; Rats; Rats, Wistar | 1993 |
Evidence for bidirectional histamine transport by murine hematopoietic progenitor cells.
Topics: Animals; Biological Transport; Calcium; Cell Line; Cetirizine; Cimetidine; Female; Hematopoietic Stem Cells; Histamine; Histamine Antagonists; Interleukin-3; Male; Mice; Mice, Inbred C57BL; Piperidines; Pyrimidinones; Sodium | 1996 |
The in vivo pharmacology of CP-80, 633, a selective inhibitor of phosphodiesterase 4.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Cross-Over Studies; Cyclic Nucleotide Phosphodiesterases, Type 4; Eosinophil Peroxidase; Guinea Pigs; Histamine; Interleukin-1; Interleukin-6; Interleukin-8; Male; Ovalbumin; Peroxidases; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrimidinones | 1996 |
Design, synthesis and antihistaminic (H(1)) activity of some condensed 3-aminopyrimidin-4(3H)-ones.
Topics: Animals; Asphyxia; Chemical Phenomena; Chemistry, Physical; Drug Design; Guinea Pigs; Histamine; Histamine H1 Antagonists; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Muscle Contraction; Muscle, Smooth; Pyrimidinones; Spectrophotometry, Infrared; Structure-Activity Relationship | 2000 |
Modulatory role of phosphoinositide 3-kinase in gastric acid secretion.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Androstadienes; Animals; Carbachol; Cell Shape; Cells, Cultured; Cholinergic Agonists; Chromones; Cyclic AMP; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gastric Acid; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Morpholines; Mutation; Organ Culture Techniques; Parietal Cells, Gastric; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidinones; Rabbits; Receptors, Histamine H2; Signal Transduction; Time Factors; Transduction, Genetic; Wortmannin | 2007 |
Dibromotyrosine and histamine derivatives from the tropical marine sponge Aplysina sp.
Topics: Animals; Carbamates; Chromatography, Thin Layer; Histamine; Imidazoles; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Porifera; Pyrimidinones; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Tyrosine | 2010 |
Peptidergic CGRPα primary sensory neurons encode heat and itch and tonically suppress sensitivity to cold.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cold Temperature; Diphtheria Toxin; Excitatory Postsynaptic Potentials; Female; Ganglia, Spinal; Gene Expression Regulation; Green Fluorescent Proteins; Histamine; Hot Temperature; In Vitro Techniques; Lectins; Male; Mice; Mice, Transgenic; Neurofilament Proteins; Pruritus; Pyrimidinones; Reaction Time; Receptors, Calcitonin Gene-Related Peptide; Sensory Receptor Cells; Sensory Thresholds; Skin; Sural Nerve; Time Factors; TRPM Cation Channels; TRPV Cation Channels; Ubiquitin Thiolesterase | 2013 |