histamine has been researched along with pyrimethamine in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (20.51) | 18.7374 |
| 1990's | 16 (41.03) | 18.2507 |
| 2000's | 11 (28.21) | 29.6817 |
| 2010's | 3 (7.69) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Iinuma, K; Maeyama, K; Onodera, K; Tuomisto, L; Watanabe, T; Yanai, K; Yokoyama, H | 1 |
| Maeyama, K; Onodera, K; Sakai, N; Watanabe, T; Yanai, K | 1 |
| Frey, HH; Hashem, A; Scherkl, R | 1 |
| Lecklin, A; Tuomisto, L | 4 |
| Cumming, P; Reiner, PB; Vincent, SR | 1 |
| Tacke, U; Tuomisto, L | 1 |
| Tacke, U; Tuomisto, L; Willman, A | 1 |
| Araki, Y; Fukuda, T; Itoh, Y; Nishibori, M; Oishi, R; Saeki, K | 1 |
| Itoh, Y; Nishibori, M; Oishi, R; Saeki, K | 3 |
| Green, JP; Hough, LB; Khandelwal, JK | 1 |
| Itoh, Y; Oishi, R; Saeki, K; Yoshitomi, I | 1 |
| Loiselle, J; Wollin, A | 1 |
| Järvikylä, M; Lecklin, A; Tuomisto, L | 1 |
| Bartolini, A; Ghelardini, C; Giotti, A; Lamberti, C; Malmberg-Aiello, P | 1 |
| Männistö, PT; Tuominen, RK; Tuomisto, L | 1 |
| Duoyon, E; Lee, WS; Morrishow, AM; Prell, GD | 1 |
| Buczko, W; Godlewski, G; Malinowska, B; Schlicker, E | 1 |
| Irman-Florjanc, T | 1 |
| Fukunaga, M; Ishizawa, K; Kakinoki, H; Kamei, C | 1 |
| Bartolini, A; Ipponi, A; Malmberg-Aiello, P; Schunack, W | 1 |
| Jochem, J | 5 |
| Murashima, YL; Nakagawa, Y; Nakano, K; Tanaka, K; Watanabe, Y; Yawata, I | 1 |
| Irman-Florjanc, T; Jochem, J; Zwirska-Korczala, K | 1 |
| Adachi, N; Arai, T; Liu, K; Motoki, A; Semba, K | 1 |
| Shatskova, AB; Tuomisto, L; Vinogradova, LV | 1 |
| Bazyan, AS; Birioukova, LM; Kuznetsova, GD; Midzyanovskaya, IS; Samotaeva, IS; Tuomisto, L | 1 |
| Hall, FS; Igarashi, K; Kitanaka, J; Kitanaka, N; Kobori, S; Kushihara, S; Nishiyama, N; Oyama, H; Sasaoka, Y; Sato, T; Takechi, M; Tanaka, KI; Tomita, K; Uhl, GR | 1 |
39 other study(ies) available for histamine and pyrimethamine
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Histamine levels and clonic convulsions of electrically-induced seizure in mice: the effects of alpha-fluoromethylhistidine and metoprine.
Topics: Animals; Brain Chemistry; Electroshock; Histamine; Histidine; Histidine Decarboxylase; Injections, Intraperitoneal; Male; Methylhistidines; Mice; Mice, Inbred Strains; Pyrimethamine | 1992 |
Effects of (S)-alpha -fluoromethylhistidine and metoprine on locomotor activity and brain histamine content in mice.
Topics: Animals; Behavior, Animal; Brain Chemistry; Histamine; Histamine N-Methyltransferase; Histidine Decarboxylase; Injections, Intraperitoneal; Male; Methylhistidines; Mice; Mice, Inbred ICR; Motor Activity; Pyrimethamine | 1992 |
Importance of histamine for seizure susceptibility.
Topics: Animals; Brain; Brocresine; Dimethindene; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histidine Decarboxylase; Male; Mice; Pentylenetetrazole; Promethazine; Pyrimethamine; Seizures | 1991 |
Histamine: a neurotransmitter that influences food intake?
Topics: Animals; Brain; Eating; Folic Acid Antagonists; Histamine; Male; Pyrimethamine; Rats; Rats, Inbred Strains | 1990 |
Feed intake after inhibition of histamine catabolism.
Topics: Animals; Brain Chemistry; Eating; Folic Acid Antagonists; Histamine; Histidine; Hypothalamus; Injections, Intraventricular; Male; Methylhistidines; Pyrimethamine; Rats; Rats, Inbred Strains | 1990 |
Inhibition of rat brain histamine-N-methyltransferase by 9-amino-1,2,3,4-tetrahydroacridine (THA).
Topics: 4-Aminopyridine; Aminoacridines; Animals; Antineoplastic Agents; Brain; Histamine; Histamine N-Methyltransferase; Injections, Intraperitoneal; Male; Methyltransferases; Physostigmine; Pyrimethamine; Rats; Tacrine | 1990 |
Is histamine an anticonvulsive inhibitory transmitter?
Topics: Animals; Electroshock; Female; Histamine; Histamine N-Methyltransferase; Male; Neural Inhibition; Pyrimethamine; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission | 1986 |
Inhibition of sound-induced convulsions by metoprine in the audiogenic seizure susceptible rat.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Brain; Histamine; Male; Neural Inhibition; Pyrimethamine; Rats; Seizures; Synaptic Transmission | 1987 |
Histamine turnover in the brain of morphine-dependent mice.
Topics: Animals; Brain; Folic Acid Antagonists; Histamine; Histidine; Male; Methylhistamines; Mice; Mice, Inbred Strains; Morphine Dependence; Naloxone; Pargyline; Pyrimethamine; Substance Withdrawal Syndrome | 1988 |
Mechanism of the central hyperglycemic action of histamine in mice.
Topics: Adrenalectomy; Animals; Blood Glucose; Chlorpheniramine; Chromatography, High Pressure Liquid; Corticosterone; Dose-Response Relationship, Drug; Epinephrine; Histamine; Hyperglycemia; Mice; Norepinephrine; Phentolamine; Promethazine; Propranolol; Pyrilamine; Pyrimethamine; Receptors, Histamine H1; Receptors, Histamine H2; Time Factors | 1987 |
Inhibition of brain histamine metabolism by metoprine.
Topics: Animals; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Histamine; Histamine N-Methyltransferase; Imidazoles; Male; Methylation; Methylhistamines; Pyrimethamine; Rats; Time Factors | 1986 |
Brain histamine turnover enhanced by footshock.
Topics: Animals; Brain; Electroshock; Foot; Histamine; Male; Methylhistamines; Methylhistidines; Mice; Pargyline; Pyrimethamine | 1986 |
Changes in histamine metabolism in the mouse hypothalamus induced by acute administration of ethanol.
Topics: Animals; Ethanol; Histamine; Hypothalamus; Male; Methylhistamines; Methylhistidines; Mice; Mice, Inbred Strains; Pargyline; Pyrimethamine; Time Factors | 1985 |
Phencyclidine and the dynamics of mouse brain histamine.
Topics: Animals; Brain Chemistry; Histamine; Male; Methylhistamines; Methylhistidines; Mice; Mice, Inbred Strains; Phencyclidine; Potassium; Pyrimethamine; Receptors, Histamine | 1985 |
Mucosal histamine elimination and its effect on acid secretion in rabbit gastric mucosa.
Topics: Animals; Biological Transport; Gastric Acid; Gastric Mucosa; Histamine; Histamine N-Methyltransferase; Histamine Release; In Vitro Techniques; Kinetics; Methylation; Pyrimethamine; Rabbits | 1993 |
The effect of metoprine on glucoprivic feeding induced by 2-deoxy-D-glucose.
Topics: Animals; Blood Glucose; Deoxyglucose; Drinking Behavior; Feeding Behavior; Folic Acid Antagonists; Glucose; Histamine; Hypothalamus; Male; Methylhistamines; Pyrimethamine; Rats; Rats, Wistar; Urodynamics; Water-Electrolyte Balance | 1994 |
Role of histamine in rodent antinociception.
Topics: Analgesics; Animals; Histamine; Histidine; Hyperalgesia; Male; Methylhistamines; Methylhistidines; Mice; Piperidines; Pyrimethamine; Rats; Rats, Wistar; Sensory Thresholds | 1994 |
Fluid balance in rats of three different strains after inhibition of histamine catabolism.
Topics: Animals; Arginine Vasopressin; Brain Chemistry; Drinking; Histamine; Male; Osmolar Concentration; Potassium; Pyrimethamine; Rats; Rats, Brattleboro; Rats, Inbred Strains; Rats, Wistar; Sodium; Species Specificity; Urination; Water-Electrolyte Balance | 1995 |
Effect of modified brain histamine contents on prolactin and thyrotropin secretion in male rats.
Topics: Animals; Brain; Cold Temperature; Enzyme Inhibitors; Histamine; Histamine N-Methyltransferase; Histidine; Hypothalamus; Male; Methylhistidines; Prolactin; Pyrimethamine; Rats; Rats, Wistar; Stress, Physiological; Thyrotropin | 1996 |
Inhibitors of histamine methylation in brain promote formation of imidazoleacetic acid, which interacts with GABA receptors.
Topics: Animals; Brain; Gas Chromatography-Mass Spectrometry; Histamine; Imidazoles; Male; Methylation; Physostigmine; Pyrimethamine; Rats; Rats, Sprague-Dawley; Receptors, GABA; Tacrine | 1997 |
Inhibitory H3 receptors on sympathetic nerves of the pithed rat: activation by endogenous histamine and operation in spontaneously hypertensive rats.
Topics: Adrenergic Fibers; Animals; Blood Pressure; Decerebrate State; Electric Stimulation; Histamine; Histamine Agonists; Histamine Antagonists; Hypertension; Imidazoles; Male; Methylhistamines; Piperidines; Pyrimethamine; Rats; Rats, Wistar; Receptors, Histamine H3; Thiourea; Vagotomy; Vascular Resistance | 1997 |
Effects of tele-methylhistamine and metoprine on plasma levels of histamine and on its elimination from cat plasma.
Topics: Animals; Cats; Enzyme Inhibitors; Female; Half-Life; Histamine; Histamine N-Methyltransferase; Kinetics; Male; Methylhistamines; Pyrimethamine | 1997 |
The blockade of H1 receptors attenuates the suppression of feeding and diuresis induced by inhibition of histamine catabolism.
Topics: Animals; Brain Chemistry; Diuresis; Enzyme Inhibitors; Feeding Behavior; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Piperidines; Pyrilamine; Pyrimethamine; Ranitidine; Rats; Rats, Wistar; Water-Electrolyte Balance | 1998 |
Histaminergic mechanisms in amygdaloid-kindled seizures in rats.
Topics: Amygdala; Animals; Brain; Histamine; Histamine Antagonists; Histidine; Kindling, Neurologic; Male; Pyrimethamine; Rats; Rats, Wistar; Seizures | 1998 |
Antiamnesic effect of metoprine and of selective histamine H(1) receptor agonists in a modified mouse passive avoidance test.
Topics: Amnesia; Animals; Avoidance Learning; Enzyme Inhibitors; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine N-Methyltransferase; Male; Memory; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Nootropic Agents; Piracetam; Pyrilamine; Pyrimethamine; Receptors, Histamine H1; Scopolamine; Thiazoles | 2000 |
Inhibition of histamine catabolism suppresses fat intake but not the intake of carbohydrates and protein.
Topics: Animals; Appetite; Caseins; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Eating; Energy Metabolism; Histamine; Male; Pyrimethamine; Rats; Rats, Wistar | 2002 |
Involvement of the sympathetic nervous system in the reversal of critical haemorrhagic hypotension by endogenous central histamine in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine Derivatives; Blood Pressure; Brain; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Hexamethonium; Histamine; Histamine N-Methyltransferase; Hypotension; Male; Muscarinic Antagonists; Nicotinic Antagonists; Pyrimethamine; Rats; Rats, Wistar; Regional Blood Flow; Shock, Hemorrhagic; Sympathetic Nervous System | 2004 |
Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Brain Chemistry; Captopril; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hindlimb; Histamine; Histamine N-Methyltransferase; Hypotension; Hypothalamus; Imidazoles; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Male; Medulla Oblongata; Naphthyridines; Pyridines; Pyrimethamine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Resuscitation; Shock, Hemorrhagic; Time Factors; Vascular Resistance | 2004 |
Involvement of proopiomenalocortin-derived peptides in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; Brain Chemistry; Disease Models, Animal; Heart Rate; Hemorrhage; Hindlimb; Histamine; Hypotension; Injections, Intraventricular; Injections, Subcutaneous; Male; Mifepristone; Peptides, Cyclic; Pro-Opiomelanocortin; Pyrimethamine; Rats; Rats, Wistar; Receptor, Melanocortin, Type 4; Regional Blood Flow; Renal Circulation; Shock, Hemorrhagic; Splanchnic Circulation; Time Factors | 2004 |
Involvement of arginine vasopressin in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Blood Pressure; Cardiovascular System; Epinephrine; Hemorrhage; Histamine; Hypotension; Immunoenzyme Techniques; Male; Pyrimethamine; Rats; Rats, Wistar; Receptors, Vasopressin; Time Factors | 2004 |
Cardiac and regional haemodynamic effects of histamine N-methyltransferase inhibitor metoprine in haemorrhage-shocked rats.
Topics: Animals; Blood Pressure; Cardiovascular System; Cerebral Cortex; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Heart Rate; Histamine; Histamine N-Methyltransferase; Hypotension; Hypothalamus; Inflammation; Ketamine; Male; Medulla Oblongata; Pyrimethamine; Rats; Rats, Wistar; Shock, Hemorrhagic; Time Factors | 2004 |
Role of histaminergic neurons in development of epileptic seizures in EL mice.
Topics: Animals; Brain; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Epilepsy; Epilepsy, Temporal Lobe; Female; Genetic Predisposition to Disease; Histamine; Histamine H1 Antagonists; Histamine N-Methyltransferase; Histidine; Histidine Decarboxylase; Male; Mice; Mice, Neurologic Mutants; Neurons; Pyrimethamine; Receptors, Histamine H3; Up-Regulation | 2004 |
The role of peripherally acting histamine in metoprine-induced reversal of haemorrhagic hypotension in rats--skeletal muscle microcirculatory studies.
Topics: Animals; Hemorrhage; Histamine; Hypotension; Male; Microcirculation; Muscle, Skeletal; Pyrimethamine; Rats; Rats, Inbred WKY; Shock, Hemorrhagic; Survival Rate | 2005 |
Reduction in brain infarction by augmentation of central histaminergic activity in rats.
Topics: Animals; Cerebral Infarction; Extracellular Space; Histamine; Histamine Antagonists; Histidine; Male; Piperidines; Pyrimethamine; Rats; Rats, Wistar | 2005 |
Histaminergic modulation of acoustically induced running behavior in rats.
Topics: Acoustic Stimulation; Animals; Brain; Brain Chemistry; Brain Stem; Enzyme Inhibitors; Epilepsy, Reflex; Epilepsy, Tonic-Clonic; Female; Histamine; Histamine N-Methyltransferase; Hyperkinesis; Injections, Intraperitoneal; Male; Nerve Net; Neural Pathways; Pyrimethamine; Rats; Rats, Mutant Strains; Rats, Wistar | 2007 |
Metoprine induced behavioral modifications and brain regional histamine increase in WAG/Rij and Wistar rats.
Topics: Animals; Behavior, Animal; Brain Chemistry; Electroencephalography; Enzyme Inhibitors; Epilepsy; Epilepsy, Absence; Epilepsy, Reflex; Grooming; Histamine; Male; Motor Activity; Pyrimethamine; Rats; Rats, Wistar; Stereotyped Behavior | 2012 |
Metoprine, a histamine N-methyltransferase inhibitor, attenuates methamphetamine-induced hyperlocomotion via activation of histaminergic neurotransmission in mice.
Topics: Animals; Behavior, Animal; Dopamine; Enzyme Inhibitors; Feeding Behavior; Histamine; Histamine N-Methyltransferase; Hypothalamus; Locomotion; Male; Methamphetamine; Mice; Mice, Inbred ICR; Nucleus Accumbens; Pyrimethamine; Stereotyped Behavior; Synaptic Transmission | 2021 |