histamine has been researched along with leukotriene c4 in 72 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 39 (54.17) | 18.2507 |
2000's | 21 (29.17) | 29.6817 |
2010's | 8 (11.11) | 24.3611 |
2020's | 4 (5.56) | 2.80 |
Authors | Studies |
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Adt, M; Arbustini, E; Lampärter, B; Marinò, I; Marone, G; Patella, V | 1 |
Inoue, H; Koshihara, Y; Nagata, N | 1 |
Binder, BR; Gajdzik, L; Graf, J; Maier, M; Tschugguel, W; Zhegu, Z | 1 |
Georgitis, JW; Matthews, BL; Stone, B | 1 |
Clement, P; Derde, MP; Smitz, J; Wang, D | 2 |
Brink, C; Cavero, I; De Montpreville, V; Gorenne, I; Guillet, MC; Labat, C; Norel, X | 1 |
Kurosawa, M; Miyachi, Y; Tsukagoshi, H; Yodonawa, S | 1 |
Graamans, K; Huizing, EH; Schuil, PJ; ten Berge, M; van Gelder, JM | 1 |
Clement, P; De Waele, M; Derde, MP; Smitz, J; Wang, D | 1 |
Austin, CE; Darby, YC; Scadding, GK | 1 |
Barrett, D; Biskin, N; Small, P | 1 |
Christie, PE; Lee, TH; Schmitz-Schumann, M; Spur, BW | 1 |
Fleisch, JH; Rinkema, LE; Roman, CR; Spaethe, SM; VanAlstyne, EL | 1 |
Kurosawa, M; Tsukagoshi, H | 1 |
Becker, I; Huber, W; Peskar, BM; Schenck, U; Schepp, W; Trautmann, M | 1 |
Itoh, K; Mukaiyama, O; Satoh, Y; Takahashi, E; Yamaguchi, T | 1 |
Heimbürger, M; Palmblad, JE | 1 |
Arbustini, E; Ciccarelli, A; Concardi, M; de Crescenzo, G; de Paulis, A; Marinò, I; Marone, G; Verga, L | 1 |
Brummer-Korvenkontio, H; François, G; Harvima, IT; Harvima, RJ; Horsmanheimo, L; Reunala, T | 1 |
Biggs, DF; Handley, DA; Jafarian, A | 1 |
Clement, P; Smitz, J; Wang, D; Waterschoot, S | 1 |
Fox, LG; Gagari, E; Galli, SJ; Lantz, CS; Tsai, M | 1 |
Hsieh, KH | 1 |
Anadol, Z; Bayram, O; Bozkurt, S; Ercan, ZS; Ersoy, E; Onuk, E; Tekýn, HE | 1 |
Behrendt, H; Beil, D; Kinder, H; Paschke, A; Ring, J; Steinhart, H; Vieluf, D | 1 |
Ashida, K; Hosaki, Y; Mifune, T; Mitsunobu, F; Tanizaki, Y; Tsugeno, H; Yokota, S | 1 |
Drouet, M; el Founini, M; Sabbah, A | 1 |
Chapman, ID; Chilvers, ER; Handley, DA; Morley, J; Templeton, AG | 1 |
Aritake, K; Hayashi, K; Hayashi, M; Hirotsu, I; Hizue, M; Kimura, Y; Matsushita, N; Mitsui, K; Nakajima, H; Takada, A; Tani, T | 1 |
Ito, K; Nakagawa, T; Tadokoro, K; Takafuji, S | 1 |
Carvalho-Tavares, J; Fox-Robichaud, A; Kubes, P | 1 |
Malaviya, R; Uckun, FM | 1 |
Asai, S; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Takao, A | 1 |
Gibelli, S; Lorini, M; Miadonna, A; Milazzo, N; Salmaso, C; Tedeschi, A | 1 |
Cordoba-Rodriguez, R; Kao, JP; Moore, KA; Weinreich, D | 1 |
Matsui, T; Nakasato, H; Ohrui, T; Sasaki, H; Sekizawa, K; Tamura, G; Yamaya, M | 1 |
Branscheid, D; Magnussen, H; Rabe, KF; Ruehlmann, E; Schmidt, D | 1 |
Kurosawa, M; Tsukagoshi, H; Yodonawa, S | 1 |
Blom, R; Karimi, K; Nijkamp, FP; Redegeld, FA | 1 |
Harvima, IT; Harvima, RJ; Saarinen, JV; Taskila, K | 1 |
Branscheid, D; Dent, G; Magnussen, H; Rabe, KF; Rühlmann, E; Schmidt, DT; Watson, N | 1 |
Fukuoka, M; Haraguchi, R; Itoh, M; Kubo, H; Muraki, M; Nakajima, S; Tohda, Y | 1 |
Lichtenstein, LM; MacGlashan, DW; Schroeder, JT | 1 |
Berlin, A; Hogaboam, CM; Lukacs, NW; Oliveira, SH | 1 |
Austen, KF; Gurish, MF | 1 |
Gleich, GJ; Kubo, H; Loegering, DJ; McCormick, DJ; Spillard, K; Thomas, LL; Weaver, AJ; Weiler, C | 1 |
Gao, C; Gao, N; Gao, X; Hu, HZ; Kim, G; Liu, S; Peck, OC; Wang, G; Wang, X; Wood, JD; Xia, Y | 1 |
Bellou, A; Gerard, P; Gillois, P; Guéant, JL; Lambert, H; Longrois, D; Mallié, JP; Montémont, C; Sainte-Laudy, J; Vauthier, E | 1 |
Gras, J; Llenas, J; Llupià, J | 1 |
Bieneman, AP; Chen, YH; Chichester, KL; Creticos, PS; Schroeder, JT | 1 |
Lai, YL; Lin, TY | 1 |
Bradding, P; Brightling, CE; Cruse, G; Duffy, SM; Kaur, D; Yang, W | 1 |
Engels, F; Mortaz, E; Nijkamp, FP; Redegeld, FA; van der Heijden, MW; Wong, HR | 1 |
Lai, YL; Lin, CH | 1 |
Hiedayati, N; Liu, S; Maeyama, K; Shudou, M | 1 |
Ackermann, L; Harvima, IT; Nuutinen, P | 1 |
Burstein, R; Levy, D; Strassman, AM; Zhang, XC | 1 |
Farooque, SP; Lee, TH; Woszczek, G | 1 |
Adkinson, NF; Celik, GE; Hamilton, RG; Saini, SS; Schroeder, JT | 1 |
Di Sotto, A; Mazzanti, G; Nicoletti, M; Piccin, A; Vitalone, A | 1 |
Birmingham, N; Busse, P; Cao, J; Goldfarb, J; Li, XM; Srivastava, K; Wen, MC; Yang, N; Zhang, T | 1 |
Church, MK; Maurer, M | 1 |
Bachmann, D; Brumatti, G; Dahinden, CA; Echeverry, N; Ekert, PG; Gurzeler, U; Kaufmann, T; Rabachini, T; Salmanidis, M; Simon, HU | 1 |
Ahmed, LA; El-Maraghy, SA; Rizk, SM | 1 |
Kuda, Y; Kurata, Y; Shibamoto, T; Song, J; Tanida, M; Wang, M; Zhang, T | 1 |
Kuda, Y; Kurata, Y; Mukai, K; Shibamoto, T; Song, J; Tanida, M; Wang, M; Zhang, T | 1 |
Bae, Y; Choi, JH; Choi, YH; Hong, GU; Kwon, IH; Park, GH; Ro, JY | 1 |
Li, E; Wang, D; Wang, J; Xue, Y; Yan, J | 1 |
Athari, SS; Hassanpour, F; Mehrabi Nasab, E; Shen, Y | 1 |
Casolaro, V; de Paulis, A; Marone, G; Poto, R; Quinti, I; Taglialatela, M; Varricchi, G | 1 |
Liuo, Y; Mehrabi Nasab, E; Yonghua, S | 1 |
3 review(s) available for histamine and leukotriene c4
Article | Year |
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Human basophils: mediator release and cytokine production.
Topics: Animals; Antigens, Surface; Basophils; Cell Division; Cytokines; Histamine; Humans; Hypersensitivity; Leukotriene C4; Signal Transduction | 2001 |
The diverse roles of mast cells.
Topics: Animals; Cell Lineage; Corticotropin-Releasing Hormone; Cytokines; Histamine; Humans; Inflammation; Leukotriene C4; Mast Cells; Serine Endopeptidases | 2001 |
Leukotriene E4: perspective on the forgotten mediator.
Topics: Animals; Aspirin; Asthma; Bronchial Hyperreactivity; Drug Hypersensitivity; Histamine; Humans; Leukotriene C4; Leukotriene D4; Leukotriene E4; Methacholine Chloride; Receptors, Leukotriene; Skin | 2009 |
4 trial(s) available for histamine and leukotriene c4
Article | Year |
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Effect of short-term treatment with fluticasone propionate nasal spray on the response to nasal allergen challenge.
Topics: Administration, Intranasal; Adult; Allergens; Androstadienes; Anti-Inflammatory Agents; Female; Fluticasone; Glucocorticoids; Histamine; Humans; Inspiratory Capacity; Leukotriene C4; Male; Middle Aged; Nasal Lavage Fluid; Poaceae; Pollen; Prostaglandin D2; Radioimmunoassay; Rhinitis, Allergic, Seasonal | 1994 |
Effects of intensity of early response to allergen on the late phase of both the nose and skin.
Topics: Adolescent; Adult; Allergens; Blood Proteins; Eosinophil Granule Proteins; Female; Histamine; Humans; Leukotriene C4; Male; Middle Aged; Nasal Cavity; Nasal Provocation Tests; Pollen; Prostaglandin D2; Radioimmunoassay; Ribonucleases; Skin; Skin Physiological Phenomena; Skin Tests; Time Factors | 1994 |
Evaluation of efficacy of traditional Chinese medicines in the treatment of childhood bronchial asthma: clinical trial, immunological tests and animal study. Taiwan Asthma Study Group.
Topics: Adolescent; Animals; Asthma; Bronchi; Bronchoalveolar Lavage Fluid; Child; Dinoprostone; Double-Blind Method; Drug Monitoring; Drugs, Chinese Herbal; Eosinophilia; Eosinophils; Female; Guinea Pigs; Histamine; Humans; Interferon-gamma; Interleukin-4; Kidney; Leukotriene C4; Lymphocyte Subsets; Male; Ovalbumin; Peak Expiratory Flow Rate; Severity of Illness Index; Spleen; Surveys and Questionnaires; Vaccination | 1996 |
Inflammatory skin responses induced by icatibant injection are mast cell mediated and attenuated by H(1)-antihistamines.
Topics: Adrenergic beta-Antagonists; Bradykinin; Drug Eruptions; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Leukotriene C4; Mast Cells; Piperazines; Prostaglandin D2; Tryptases | 2012 |
65 other study(ies) available for histamine and leukotriene c4
Article | Year |
---|---|
Human heart mast cells. Isolation, purification, ultrastructure, and immunologic characterization.
Topics: Cell Separation; Chromatography, High Pressure Liquid; Chymases; Complement C5a; Histamine; Histamine Release; Humans; Immunoglobulin E; Leukotriene C4; Lung; Mast Cells; Microscopy, Immunoelectron; Myocardium; Prostaglandin D2; Radioimmunoassay; Receptors, IgE; Serine Endopeptidases; Skin; Synovial Membrane; Tryptases | 1995 |
Inhibition by actinomycin D of neurogenic mouse ear oedema.
Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Capsaicin; Cycloheximide; Dactinomycin; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Ear Diseases; Edema; Histamine; Injections, Intravenous; Leukotriene C4; Male; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin; Substance P; Tachykinins; Vasoactive Intestinal Peptide | 1995 |
High precision measurement of electrical resistance across endothelial cell monolayers.
Topics: Bradykinin; Calcimycin; Cells, Cultured; Electric Impedance; Endothelium, Vascular; Histamine; Humans; Leukotriene C4; Platelet Activating Factor; Thrombin; Umbilical Veins | 1995 |
Chronic sinusitis: characterization of cellular influx and inflammatory mediators in sinus lavage fluid.
Topics: Adolescent; Adult; Aged; Basophils; Body Fluids; Cell Count; Cell Degranulation; Child; Chronic Disease; Female; Histamine; Humans; Leukotriene C4; Leukotriene D4; Leukotriene E4; Male; Mast Cells; Middle Aged; Prostaglandin D2; Sinusitis; Therapeutic Irrigation | 1995 |
Concentrations of chemical mediators in nasal secretions after nasal allergen challenges in atopic patients.
Topics: Adolescent; Adult; Allergens; Blood Proteins; Case-Control Studies; Chymases; Eosinophil Granule Proteins; Female; Follow-Up Studies; Histamine; Humans; Inflammation Mediators; Inhalation; Leukotriene C4; Male; Middle Aged; Nasal Mucosa; Nasal Obstruction; Nasal Provocation Tests; Prostaglandin D2; Rhinitis, Allergic, Seasonal; Ribonucleases; Serine Endopeptidases; Sneezing; Tryptases | 1995 |
Effects of beta 2-adrenoceptor agonists on anti-IgE-induced contraction and smooth muscle reactivity in human airways.
Topics: Acetylcholine; Adrenergic beta-2 Receptor Agonists; Bronchi; Histamine; Humans; Immunoglobulin E; In Vitro Techniques; Leukotriene C4; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth | 1995 |
Concentrations of chemical mediators in nasal secretions of patients with hay fever during natural allergen exposure.
Topics: Adolescent; Adult; Allergens; Blood Proteins; Chymases; Eosinophil Granule Proteins; Female; Histamine; Humans; Inflammation Mediators; Leukotriene C4; Male; Manometry; Middle Aged; Nasal Mucosa; Nose; Rhinitis, Allergic, Seasonal; Ribonucleases; Serine Endopeptidases; Tryptases | 1994 |
Inhibition by a novel peptide leukotriene receptor antagonist ONO-1078 of airway wall thickening and airway hyperresponsiveness to histamine induced by leukotriene C4 or leukotriene D4 in guinea-pigs.
Topics: Airway Resistance; Animals; Bronchial Hyperreactivity; Chromones; Guinea Pigs; Histamine; Image Processing, Computer-Assisted; Infusions, Intravenous; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Lung; Male; SRS-A | 1994 |
Histamine and leukotriene C4 effects on in vitro ciliary beat frequency of human upper respiratory cilia.
Topics: Adenoids; Child; Cilia; Culture Techniques; Dose-Response Relationship, Drug; Epithelium; Histamine; Humans; Leukotriene C4; Mucociliary Clearance | 1994 |
Correlations between complaints, inflammatory cells and mediator concentrations in nasal secretions after nasal allergen challenge and during natural allergen exposure.
Topics: Adolescent; Adult; Allergens; Blood Proteins; Chymases; Eosinophil Granule Proteins; Female; Histamine; Humans; Inflammation; Inflammation Mediators; Leukotriene C4; Male; Middle Aged; Nasal Mucosa; Nasal Provocation Tests; Rhinitis, Allergic, Seasonal; Ribonucleases; Serine Endopeptidases; Tryptases | 1995 |
Airway responsiveness to leukotriene C4 (LTC4), leukotriene E4 (LTE4) and histamine in aspirin-sensitive asthmatic subjects.
Topics: Adolescent; Adult; Aspirin; Asthma; Female; Forced Expiratory Volume; Histamine; Humans; Leukotriene C4; Leukotriene E4; Lysine; Male; Middle Aged; Respiratory System | 1993 |
Contraction of guinea pig inferior vena cava by eicosanoids.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetophenones; Animals; Eicosanoids; Guinea Pigs; Histamine; Hydroxyquinolines; In Vitro Techniques; Leukotriene C4; Leukotriene E4; Male; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; SRS-A; Tetrazoles; Thromboxane A2; Vena Cava, Inferior | 1993 |
Inhibitory effect of a thromboxane A2 synthetase inhibitor OKY-046 on bronchial hyperresponsiveness to histamine, but not on airway wall thickening, induced by intravenous administration of leukotriene C4 in guinea-pigs.
Topics: Airway Resistance; Animals; Bronchi; Bronchial Hyperreactivity; Guinea Pigs; Histamine; Histamine Antagonists; Injections, Intravenous; Leukotriene C4; Male; Methacrylates; Thromboxane-A Synthase | 1993 |
Leukotriene B4 and C4 production in isolated rat gastric mucosal cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cell Separation; Colforsin; Diglycerides; Female; Gastric Mucosa; Histamine; In Vitro Techniques; Interleukin-1; Interleukin-2; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Pentagastrin; Phenothiazines; Platelet Activating Factor; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
Relationship between airway eosinophilia and airway hyperresponsiveness in a late asthmatic model of guinea pigs.
Topics: Animals; Antibodies; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstrictor Agents; Disease Models, Animal; Eosinophils; Guinea Pigs; Histamine; Interleukin-5; Leukocyte Count; Leukotriene C4; Male; Methacholine Chloride; Ovalbumin; Passive Cutaneous Anaphylaxis; Pulmonary Eosinophilia; Thromboxane B2; Time Factors | 1996 |
Effects of leukotriene C4 and D4, histamine and bradykinin on cytosolic calcium concentrations and adhesiveness of endothelial cells and neutrophils.
Topics: Amino Acid Sequence; Bradykinin; Calcium; Cell Adhesion; Cytosol; Dicarboxylic Acids; Endothelium, Vascular; Histamine; Humans; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Membrane Proteins; Molecular Sequence Data; Neutrophils; Receptors, Leukotriene; Signal Transduction; Stimulation, Chemical | 1996 |
Human synovial mast cells. I. Ultrastructural in situ and in vitro immunologic characterization.
Topics: Adult; Aged; Antibodies, Anti-Idiotypic; Cell Movement; Chymases; Histamine; Humans; Leukotriene C4; Mast Cells; Middle Aged; p-Methoxy-N-methylphenethylamine; Prostaglandin D2; Serine Endopeptidases; Stem Cell Factor; Substance P; Synovial Membrane; Tryptases | 1996 |
Histamine and leukotriene C4 release in cutaneous mosquito-bite reactions.
Topics: Adult; Aedes; Animals; Female; Histamine; Histamine Release; Humans; Insect Bites and Stings; Leukotriene C4; Male; Microdialysis; Middle Aged; Skin | 1996 |
Effects of RS-albuterol on the development of antigen-mediated airway hyperreactivity in guinea pigs.
Topics: Aerosols; Albuterol; Animals; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Immune Sera; Immunization, Passive; Leukotriene C4; Ovalbumin; Stereoisomerism | 1996 |
An approach to the understanding of the nasal early-phase reaction induced by nasal allergen challenge.
Topics: Adult; Allergens; Chymases; Female; Histamine; Humans; Leukotriene C4; Male; Nasal Mucosa; Nasal Obstruction; Nasal Provocation Tests; Pruritus; Serine Endopeptidases; Sneezing; Tryptases | 1997 |
Differential release of mast cell interleukin-6 via c-kit.
Topics: Animals; Cell Survival; Histamine; Immunoglobulin E; Interleukin-6; Leukotriene C4; Lipopolysaccharides; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Peritoneal Cavity; Proto-Oncogene Proteins c-kit; Rats; Recombinant Proteins; Serotonin; Stem Cell Factor; Tumor Necrosis Factor-alpha | 1997 |
The cytoprotective effect of iloprost against carbon tetrachloride induced necrosis in rat liver.
Topics: Animals; Carbon Tetrachloride; Dinoprostone; Disease Models, Animal; Female; Histamine; Hypertension, Portal; Iloprost; Injections, Subcutaneous; Leukotriene C4; Liver; Liver Cirrhosis, Experimental; Male; Platelet Aggregation Inhibitors; Rats; Vasodilator Agents | 1997 |
Determination of histamine and leukotrienes from basophils in cell supernatants by high-performance liquid chromatography.
Topics: Basophils; Centrifugation, Density Gradient; Chromatography, High Pressure Liquid; Histamine; Humans; Indicators and Reagents; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Spectrometry, Fluorescence | 1998 |
Different roles of histamine and leukotriene C4 in the airways between patients with atopic and nonatopic asthma.
Topics: Adult; Aging; Asthma; Blood Cells; Bronchi; Bronchoalveolar Lavage Fluid; Calcimycin; Female; Histamine; Humans; Hypersensitivity; Ionophores; Leukotriene C4; Male; Middle Aged; Pulmonary Alveoli | 1998 |
[Importance of the urinary leukotriene E4 level. Preliminary study].
Topics: Acetaminophen; Anaphylaxis; Anesthetics; Aspirin; Biomarkers; Chymases; Drug Hypersensitivity; Histamine; Humans; Leukotriene C4; Leukotriene E4; Postoperative Complications; Serine Endopeptidases; Tryptases | 1998 |
Effects of S-salbutamol on human isolated bronchus.
Topics: Adenosine; Albuterol; Bradykinin; Bronchi; Bronchoconstriction; Bronchodilator Agents; Capsaicin; Histamine; Humans; Hypersensitivity; In Vitro Techniques; Leukotriene C4; Methacholine Chloride; Platelet Activating Factor | 1998 |
Pharmacological studies on the novel antiallergic drug HQL-79: II. Elucidation of mechanisms for antiallergic and antiasthmatic effects.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Antigens; Capillary Permeability; Dibenzazepines; Dinoprostone; Dose-Response Relationship, Drug; Free Radical Scavengers; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine Release; Ileum; Imidazoles; In Vitro Techniques; Intramolecular Oxidoreductases; Ketotifen; Leukotriene B4; Leukotriene C4; Lipocalins; Lung; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Piperidines; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Respiratory Hypersensitivity; Serotonin; Sheep; Skin Physiological Phenomena; Trachea | 1998 |
Release of granule proteins from human eosinophils stimulated with mast-cell mediators.
Topics: Blood Proteins; Calcium; Chemotactic Factors, Eosinophil; Cytokines; Cytosol; Dinoprostone; Dose-Response Relationship, Drug; Eosinophil Granule Proteins; Eosinophils; Histamine; Humans; Inflammation Mediators; Kinetics; Leukotriene B4; Leukotriene C4; Mast Cells; Platelet Activating Factor; Prostaglandin D2; Ribonucleases | 1998 |
Assessment of the mechanism of juxtacrine activation and adhesion of leukocytes in liver microcirculation.
Topics: Animals; Cell Adhesion; Enzyme Inhibitors; Gene Expression Regulation; Guanidines; Histamine; Intercellular Adhesion Molecule-1; Kinetics; Leukocytes; Leukotriene C4; Liver Circulation; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Microcirculation; P-Selectin; Platelet Activating Factor; Venules | 1999 |
Genetic and biochemical evidence for a critical role of Janus kinase (JAK)-3 in mast cell-mediated type I hypersensitivity reactions.
Topics: Animals; Bone Marrow Cells; Cell Degranulation; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Dinitrophenols; Gene Deletion; Histamine; Hypersensitivity; Immunoglobulin E; Janus Kinase 3; Leukotriene C4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Protein-Tyrosine Kinases; Quinazolines; Receptor Aggregation; Receptors, IgE; Stem Cell Factor | 1999 |
Inhibitory effects of azelastine hydrochloride in alcohol-induced asthma.
Topics: Acetaldehyde; Adult; Aged; Asthma; Bronchoconstrictor Agents; Bronchodilator Agents; Ethanol; Female; Histamine; Humans; Leukotriene C4; Male; Middle Aged; Phthalazines; Respiratory Function Tests; Thromboxane B2 | 1999 |
Nasal response to a single antigen challenge in patients with allergic rhinitis - inflammatory cell recruitment persists up to 48 hours.
Topics: Adolescent; Adult; Antigens; Blood Proteins; Chemotaxis, Leukocyte; Eosinophil Granule Proteins; Eosinophils; Female; Histamine; Humans; Leukocytes, Mononuclear; Leukotriene B4; Leukotriene C4; Male; Nasal Lavage Fluid; Nasal Provocation Tests; Neutrophils; Peroxidase; Pollen; Prostaglandin D2; Radioimmunoassay; Rhinitis, Allergic, Seasonal; Ribonucleases | 1999 |
Calcium regulation of a slow post-spike hyperpolarization in vagal afferent neurons.
Topics: Action Potentials; Animals; Bradykinin; Calcium; Calcium Channel Blockers; Calcium Channels; Dinoprostone; Evoked Potentials; Guinea Pigs; Histamine; Leukotriene C4; Neurons, Afferent; Nodose Ganglion; Prostaglandin D2; Rabbits; Serotonin; Vagus Nerve | 1999 |
Prevention of severe premenstrual asthma attacks by leukotriene receptor antagonist.
Topics: Adolescent; Adult; Anti-Asthmatic Agents; Asthma; Chromones; Cytokines; Female; Histamine; Humans; Leukotriene Antagonists; Leukotriene B4; Leukotriene C4; Mast Cells; Menstruation; Peak Expiratory Flow Rate; T-Lymphocytes | 1999 |
Passive sensitization of human airways increases responsiveness to leukotriene C4.
Topics: Adult; Aged; Allergens; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Carbachol; Dose-Response Relationship, Drug; Female; Histamine; Humans; Immunoglobulin E; In Vitro Techniques; Isoproterenol; Leukotriene C4; Male; Middle Aged; Respiratory Hypersensitivity | 1999 |
Inhibition of bronchial hyperresponsiveness to histamine induced by intravenous administration of leukotriene C4 by novel thromboxane A2 receptor antagonists ONO-NT-126 and ONO-8809 in guinea-pigs.
Topics: Airway Resistance; Animals; Bridged Bicyclo Compounds; Bronchi; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Dose-Response Relationship, Immunologic; Edema; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Injections, Intravenous; Leukotriene C4; Male; Molecular Structure; Receptors, Thromboxane | 1993 |
Stem cell factor and interleukin-4 increase responsiveness of mast cells to substance P.
Topics: Animals; beta-N-Acetylhexosaminidases; Bone Marrow Cells; Cells, Cultured; Cytoplasmic Granules; Drug Synergism; Histamine; Interleukin-3; Interleukin-4; Leukotriene C4; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Monocyte Chemoattractant Proteins; Prostaglandin D2; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cell Factor; Substance P | 2000 |
Histamine and LTC4 in stinging nettle-induced urticaria.
Topics: Animals; Histamine; Humans; Leukotriene C4; Magnoliopsida; Microdialysis; Plant Leaves; Plant Stems; Skin Tests; Urticaria | 2000 |
The effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C(4)-induced contractions in passively sensitized human airways.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Antigens, Dermatophagoides; Benzamides; Bronchi; Bronchodilator Agents; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Glycoproteins; Histamine; Humans; In Vitro Techniques; Leukotriene C4; Lung Neoplasms; Muscle Contraction; Phosphodiesterase Inhibitors; Pyridazines; Pyridines; Rolipram; Theophylline | 2000 |
Role of chemical mediators in airway hyperresponsiveness in an asthmatic model.
Topics: Airway Resistance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Leukotriene C4; Leukotriene D4; Male; Ovalbumin; Platelet Activating Factor; Probability; Reference Values; Sensitivity and Specificity; Thromboxane A2 | 2001 |
SCF-induced airway hyperreactivity is dependent on leukotriene production.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzopyrans; Carboxylic Acids; Cells, Cultured; Female; Histamine; Indoles; Leukotriene Antagonists; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Mast Cells; Methacholine Chloride; Mice; Propionates; Quinolines; Respiratory Hypersensitivity; Signal Transduction; Stem Cell Factor; Tumor Necrosis Factor-alpha | 2001 |
Peptide-based analysis of amino acid sequences important to the biological activity of eosinophil granule major basic protein.
Topics: Amino Acid Sequence; Basophils; Blood Proteins; Cytotoxicity, Immunologic; Eosinophil Granule Proteins; Eosinophils; Histamine; Humans; K562 Cells; Leukotriene C4; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Ribonucleases; Sequence Analysis, Protein; Tumor Cells, Cultured | 2001 |
Neuroimmune interactions in guinea pig stomach and small intestine.
Topics: Anaphylaxis; Animals; Dinoprostone; Electrophysiology; Fluorescent Antibody Technique; Guinea Pigs; Histamine; Histamine Antagonists; Intestine, Small; Lactoglobulins; Leukotriene C4; Mast Cells; Membrane Potentials; Milk; Neuroimmunomodulation; Neurons; Ovalbumin; Serotonin Antagonists; Stomach; Submucous Plexus; Sympathetic Nervous System; Synaptic Transmission | 2003 |
Constitutive nitric oxide synthase inhibition combined with histamine and serotonin receptor blockade improves the initial ovalbumin-induced arterial hypotension but decreases the survival time in brown norway rats anaphylactic shock.
Topics: Anaphylaxis; Animals; Arteries; Cimetidine; Dihydroergotamine; Dinoprostone; Eicosanoids; Enzyme Inhibitors; Heart; Histamine; Hypotension; Leukotriene C4; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ovalbumin; Pressure; Rats; Rats, Inbred BN; Receptors, Serotonin; Serotonin; Thromboxane B2; Time Factors | 2003 |
Comparative antiallergic effects of second-generation H1-antihistamines ebastine, cetirizine and loratadine in preclinical models.
Topics: Aerosols; Airway Resistance; Algorithms; Animals; Anti-Allergic Agents; Bronchial Spasm; Butyrophenones; Cetirizine; Guinea Pigs; Histamine; Histamine H1 Antagonists; Leukotriene C4; Loratadine; Male; Ovalbumin; Piperidines | 2003 |
IFN-alpha inhibits IL-3 priming of human basophil cytokine secretion but not leukotriene C4 and histamine release.
Topics: Adult; Basophils; Cell Survival; Cells, Cultured; Cytokines; Histamine; Humans; Immunoglobulin E; Interferon Type I; Interferon-alpha; Interferon-gamma; Interleukin-13; Interleukin-3; Leukotriene C4; Middle Aged; Receptor, Interferon alpha-beta; Receptors, Interferon; RNA, Messenger | 2003 |
Mast cells in citric acid-induced cough of guinea pigs.
Topics: Aerosols; Animals; Citric Acid; Cough; Guinea Pigs; Histamine; Leukotriene C4; Mast Cells | 2005 |
Activation of human lung mast cells by monomeric immunoglobulin E.
Topics: Calcium; Cells, Cultured; Culture Media, Conditioned; Histamine; Humans; Immunoglobulin E; Interleukin-8; Leukotriene C4; Lung; Mast Cells; Reference Values; Stem Cell Factor | 2005 |
Mast cell activation is differentially affected by heat shock.
Topics: Animals; Calcium Signaling; Cell Degranulation; Cells, Cultured; DNA-Binding Proteins; Enzyme Precursors; Heat Shock Transcription Factors; Histamine; Histamine Release; Hot Temperature; Hypersensitivity; Inflammation; Intracellular Signaling Peptides and Proteins; Leukotriene C4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Knockout; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, IgE; Syk Kinase; Transcription Factors | 2005 |
Mast cell mediators in citric acid-induced airway constriction of guinea pigs.
Topics: Administration, Inhalation; Animals; Bronchoconstriction; Citric Acid; Cyclooxygenase Inhibitors; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Indoles; Indomethacin; Leukotriene C4; Mast Cells; p-Methoxy-N-methylphenethylamine; Prostaglandins; Pyrilamine; Serotonin | 2005 |
Activation of connective tissue-type and mucosal-type mast cells in compound 48/80-induced airway response.
Topics: Administration, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Cell Degranulation; Connective Tissue; Enzyme Induction; Histamine; Immunohistochemistry; In Situ Hybridization; Injections, Intraperitoneal; Leukotriene C4; Male; Mast Cells; Metalloendopeptidases; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Respiratory Mucosa; Respiratory System; RNA, Messenger; Tumor Necrosis Factor-alpha | 2006 |
Histamine, but not leukotriene C4, is an essential mediator in cold urticaria wheals.
Topics: Acetates; Adult; Anti-Allergic Agents; Cetirizine; Cold Temperature; Cyclopropanes; Female; Histamine; Humans; Leukotriene Antagonists; Leukotriene C4; Male; Middle Aged; Quinolines; Sulfides; Urticaria | 2007 |
Sensitization and activation of intracranial meningeal nociceptors by mast cell mediators.
Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Electrophysiology; Epoprostenol; Histamine; Leukotriene C4; Male; Mast Cells; Meninges; Nociceptors; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Serotonin; Stress, Mechanical | 2007 |
Effect of in vitro aspirin stimulation on basophils in patients with aspirin-exacerbated respiratory disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Aspirin; Asthma, Aspirin-Induced; Basophils; Cells, Cultured; Dose-Response Relationship, Drug; Female; Histamine; Histamine Release; Humans; Interleukin-4; Leukotriene C4; Male; Middle Aged | 2009 |
Pharmacological and phytochemical study on a Sisymbrium officinale Scop. extract.
Topics: Animals; Anthracenes; Antimutagenic Agents; Bacteria; Brassicaceae; Glucosinolates; Guinea Pigs; Histamine; Leukotriene C4; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Plant Components, Aerial; Plant Extracts; Proline; Sulfuric Acid Esters; Trachea; Yeasts | 2010 |
Pharmacology and immunological actions of a herbal medicine ASHMI on allergic asthma.
Topics: Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Cytokines; Drugs, Chinese Herbal; Eosinophils; Histamine; Humans; Immunoglobulin E; In Vitro Techniques; Leukotriene C4; Lung; Mice; Mice, Inbred BALB C; Molecular Structure; Myocytes, Smooth Muscle; Ovalbumin; Prostaglandins; Trachea | 2010 |
In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8.
Topics: Animals; Apoptosis; Basophils; Cell Degranulation; Cell Differentiation; Gene Expression Regulation; Hematopoietic Stem Cells; Histamine; Homeodomain Proteins; Interleukin-3; Leukotriene C4; Mice; Th2 Cells; Tryptases | 2013 |
Role of the KATP channel in the protective effect of nicorandil on cyclophosphamide-induced lung and testicular toxicity in rats.
Topics: Acetylglucosaminidase; Animals; Biomarkers; Body Weight; Cyclophosphamide; Cytokines; Glyburide; Histamine; Inflammation Mediators; KATP Channels; Leukotriene C4; Lung; Male; Nicorandil; Organ Size; Oxidative Stress; Protective Agents; Rats; Testis; Testosterone | 2015 |
The responses of pulmonary and systemic circulation and airway to anaphylactic mediators in anesthetized BALB/c mice.
Topics: Anaphylaxis; Animals; Arterial Pressure; Dose-Response Relationship, Drug; Histamine; Leukotriene C4; Male; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Prostaglandin D2; Serotonin; Vascular Resistance; Vasoconstriction; Vasodilation | 2016 |
The Responses of Pulmonary and Systemic Circulation and Airway to Allergic Mediators in Anesthetized Rats.
Topics: Anesthesia; Animals; Arterial Pressure; Blood Circulation; Histamine; Hypersensitivity; Inflammation Mediators; Leukotriene C4; Lung; Male; Platelet Activating Factor; Prostaglandin D2; Rats, Sprague-Dawley; Serotonin; Vascular Resistance; Vasoconstriction | 2016 |
Association of TG2 from mast cells and chronic spontaneous urticaria pathogenesis.
Topics: Adult; Cytokines; Female; GTP-Binding Proteins; Histamine; Humans; Immunoglobulin E; Leukotriene C4; Male; Mast Cells; Middle Aged; Protein Glutamine gamma Glutamyltransferase 2; Skin; Skin Tests; Transglutaminases; Urticaria; Young Adult | 2016 |
The Protective Role of Cirsilineol against Ovalbumin-Induced Allergic Rhinitis in Mice by Suppression of Inflammation and Oxidative Stress.
Topics: Animals; Anti-Allergic Agents; Biomarkers; Carrier Proteins; Cells, Cultured; Disease Models, Animal; Eosinophils; Flavones; Histamine; Immunoglobulin E; Leukotriene C4; Mice, Inbred BALB C; Nasal Lavage Fluid; Ovalbumin; Oxidative Stress; Prostaglandin D2; Rhinitis, Allergic; Spleen; Thioredoxins | 2021 |
The Effects of Combined Therapeutic Protocol on Allergic Rhinitis Symptoms and Molecular Determinants.
Topics: Allergens; Animals; Caspase 1; Fluticasone; Histamine; Immunoglobulin E; Leukotriene C4; Loratadine; Mice; Rhinitis, Allergic | 2022 |
IgG Autoantibodies Against IgE from Atopic Dermatitis Can Induce the Release of Cytokines and Proinflammatory Mediators from Basophils and Mast Cells.
Topics: Animals; Autoantibodies; Basophils; Cytokines; Dermatitis, Atopic; Eicosanoids; Histamine; Humans; Immunoglobulin E; Immunoglobulin G; Interleukin-13; Interleukin-4; Leukotriene C4; Mast Cells; Prostaglandins; Rabbits | 2022 |
Effect of Temperature and Humidity on the Allegro-inflammatory Factors and Allergic Rhinitis-related Behavior.
Topics: Animals; Disease Models, Animal; Histamine; Humidity; Immunoglobulin E; Interleukin-4; Leukotriene C4; Mice; Mice, Inbred BALB C; Nasal Mucosa; Ovalbumin; Rhinitis, Allergic; Sneezing; Temperature | 2022 |