histamine and jnj 7777120

histamine has been researched along with jnj 7777120 in 46 studies

Research

Studies (46)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	15 (32.61)	29.6817
2010's	30 (65.22)	24.3611
2020's	1 (2.17)	2.80

Authors

Authors	Studies
Bakker, RA; De Esch, IJ; Leurs, R; Terzioglu, N; van Rijn, RM	1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM	1
Adami, M; Coruzzi, G; de Esch, IJ; Guaita, E; Hanzer, A; Leurs, R; Lim, HD; Smits, RA; Zuiderveld, OP	1
Falus, A; Jelinek, I; Keseru, GM; Kiss, B; Kiss, R; Könczöl, A; László, V; Noszál, B; Szalai, F	1
Adami, M; Broeker, J; Coruzzi, G; de Esch, IJ; Guaita, E; Haaksma, E; Leurs, R; Sansuk, K; Smits, RA; Zuiderveld, OP	1
Kottke, T; Proschak, E; Sander, K; Schneider, EH; Schneider, G; Seifert, R; Stark, H; Tanrikulu, Y; Weizel, L	1
Buschauer, A; Dove, S; Geyer, R; Igel, P; Seifert, R; Strasser, A	1
de Esch, IJ; de Graaf, C; Istyastono, EP; Kooistra, AJ; Leurs, R; Lim, HD; Nijmeijer, S; Roumen, L; van de Stolpe, A; Vischer, HF	1
Bessembinder, K; de Esch, IJ; Kuhne, S; Leurs, R; Lim, HD; Smits, RA; van der Meer, T; Wijtmans, M; Zuiderveld, OP	1
Savall, BM; Thurmond, RL; Tichenor, MS; Venable, JD	1
Elz, S; Gobleder, S; Hammer, SG; Heinrich, MR; Naporra, F; Strasser, A; Wittmann, HJ	1
Buschauer, A; Geyer, R; Nordemann, U; Strasser, A; Wittmann, HJ	1
Desai, PJ; Dunford, PJ; Karlsson, L; McQueen, D; Thurmond, RL; Williams, KN	1
Chazot, P; Dijkstra, D; Gutzmer, R; Leurs, R; Shenton, FC; Stark, H; Werfel, T	1
Eros, D; Falus, A; Keseru, GM; Kiss, R; Noszál, B; Rácz, A	1
Jójárt, B; Keseru, GM; Kiss, R; Viskolcz, B	1
Bakker, RA; de Esch, IJ; Haaksma, E; Jongejan, A; Leurs, R; Lim, HD	1
Thurmond, RL; Tiligada, E; Zampeli, E	1
Oda, M; Sato, H; Suwa, E; Suzuki, M; Ueno, K; Yamaura, K	1
Kamitani, S; Kawasaki, S; Kohyama, T; Nagase, T; Takizawa, H; Yamauchi, Y	1
Bäumer, W; Kietzmann, M; Leurs, R; Rossbach, K; Sander, K; Stark, H	1
Beermann, S; Neumann, D; Seifert, R	1
Gschwandtner, M; Gutzmer, R; Schäkel, K; Werfel, T	1
Borrebaeck, CA; Broos, S; Greiff, L; Lindstedt, M; Lundberg, K	1
Desai, P; Thurmond, RL	1
Bäumer, W; Kietzmann, M; Olivry, T; Paps, J; Petersen, LJ; Sander, K; Stahl, J; Stark, H	1
Bergoc, RM; Cricco, GP; Croci, M; Martinel Lamas, DJ; Massari, NA; Medina, VA; Rivera, ES; Sambuco, L	1
Dartt, DA; Hayashi, C; Hayashi, D; Hodges, RR; Li, D; Shatos, M	1
Hirasawa, N; Ohsawa, Y	1
Jin, C; Karlstedt, K; Panula, P	1
Gschwandtner, M; Gutzmer, R; Koether, B; Stark, H; Werfel, T	1
Bäumer, W; Ehling, S; Glatzer, F; Gschwandtner, M; Gutzmer, R; Janik, K; Kietzmann, M; Klos, A; Rossbach, K; Werfel, T	1
Sato, S; Suwa, E; Ueno, K; Yamaura, K	1
De Man, JG; De Winter, BY; Deiteren, A; Moreels, TG; Pelckmans, PA; Ruyssers, NE	1
Brown, V; Chazot, PL; Comer, D; Dib, K; Ennis, M; Jenei, V; Katebe, M; McFarlane, C; Perecko, T; Scheithauer, T; Thurmond, RL	1
Kyriakidis, K; Palaiologou, M; Tiligada, E; Tiniakos, D; Zampeli, E	1
Camussi, G; Chazot, PL; Grange, C; Lanzi, C; Moggio, A; Pini, A; Rosa, AC; Veglia, E	1
Aromando, RF; Curotto, P; Farías, RO; Garabalino, MA; Gonzalez, SJ; Heber, EM; Itoiz, ME; Martinel Lamas, DJ; Medina, VA; Monti Hughes, A; Nigg, DW; Pozzi, E; Rivera, ES; Schwint, AE; Thorp, SI; Trivillin, VA	1
Hong, SM; Lee, HM; Park, IH; Shin, JM; Um, JY	1
Chlopicki, S; Grosicki, M; Kieć-Kononowicz, K; Wójcik, T	1
Bäumer, W; Dunston, SM; Ehling, S; Roßbach, K; Stark, H	1
Ahn, KJ; Choe, YB; Han, SH; Hur, MS; Kim, BM; Kim, HR; Kim, KW; Kim, MJ; Lee, YW	1
Barbieri van Haaster, MM; Benítez, MB; Brandt, M; González, DA; Orman, B; Quinteros Villarruel, E; Stranieri, GM	1
Ebenezer, AJ; Prasad, K; Rajan, S; Thangam, EB	1
Fang, Q; Homberg, JR; Li, W; Liao, P; Liu, C; Luan, Y; Meng, X; Shan, L; Shen, J; Swaab, DF; Wang, J; Zhou, P	1
Cremaschi, GA; Formoso, K; Herrero Ducloux, MV; Martinel Lamas, D; Massari, NA; Medina, VA; Nicoud, MB; Sterle, HA; Táquez Delgado, MA	1

Reviews

2 review(s) available for histamine and jnj 7777120

Article	Year
Functional Profiling of 2-Aminopyrimidine Histamine H4 Receptor Modulators. Journal of medicinal chemistry, 2015, Sep-24, Volume: 58, Issue:18 Topics: Aminopyridines; Animals; Arthritis, Rheumatoid; Asthma; Dermatitis, Atopic; Drug Partial Agonism; Histamine Agonists; Histamine Antagonists; Humans; Hypersensitivity; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship	2015
Does the histamine H4 receptor have a pro- or anti-inflammatory role in murine bronchial asthma? Pharmacology, 2010, Volume: 85, Issue:4 Topics: Animals; Asthma; Disease Models, Animal; Histamine; Humans; Indoles; Inflammation; Mice; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4	2010

Article

Year

Functional Profiling of 2-Aminopyrimidine Histamine H4 Receptor Modulators.

Journal of medicinal chemistry, 2015, Sep-24, Volume: 58, Issue:18

Topics: Aminopyridines; Animals; Arthritis, Rheumatoid; Asthma; Dermatitis, Atopic; Drug Partial Agonism; Histamine Agonists; Histamine Antagonists; Humans; Hypersensitivity; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship

2015

Does the histamine H4 receptor have a pro- or anti-inflammatory role in murine bronchial asthma?

Pharmacology, 2010, Volume: 85, Issue:4

Topics: Animals; Asthma; Disease Models, Animal; Histamine; Humans; Indoles; Inflammation; Mice; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4

2010

Other Studies

44 other study(ies) available for histamine and jnj 7777120

Article	Year
Synthesis and structure-activity relationships of indole and benzimidazole piperazines as histamine H(4) receptor antagonists. Bioorganic & medicinal chemistry letters, 2004, Nov-01, Volume: 14, Issue:21 Topics: Benzimidazoles; Binding, Competitive; Cell Line; Histamine H1 Antagonists; Humans; Indoles; Ligands; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship	2004
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3 Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4	2005
Fragment based design of new H4 receptor-ligands with anti-inflammatory properties in vivo. Journal of medicinal chemistry, 2008, Apr-24, Volume: 51, Issue:8 Topics: Anti-Inflammatory Agents; Drug Design; Humans; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Receptors, Histamine; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship	2008
Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening. Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Binding, Competitive; Cell Line, Tumor; Databases, Factual; Histamine Antagonists; Humans; Ligands; Models, Molecular; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship	2008
Discovery of quinazolines as histamine H4 receptor inverse agonists using a scaffold hopping approach. Journal of medicinal chemistry, 2008, Dec-25, Volume: 51, Issue:24 Topics: Animals; Anti-Inflammatory Agents; Chemistry, Pharmaceutical; Drug Design; Histamine Agonists; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4	2008
2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization. Bioorganic & medicinal chemistry, 2009, Oct-15, Volume: 17, Issue:20 Topics: Ligands; Magnetic Resonance Spectroscopy; Pyrimidines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship	2009
Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H4 receptor agonists. Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20 Topics: Animals; Drug Discovery; Guanidine; Guanidines; Guanosine Triphosphate; Histamine Agonists; Humans; Hydrolysis; Isotope Labeling; Mice; Models, Molecular; Protein Conformation; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship; Substrate Specificity	2009
Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies. Journal of medicinal chemistry, 2011, Dec-08, Volume: 54, Issue:23 Topics: Cell Line, Tumor; Histamine Antagonists; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Quantitative Structure-Activity Relationship; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Stereoisomerism; Thiourea	2011
Ligand based design of novel histamine H₄ receptor antagonists; fragment optimization and analysis of binding kinetics. Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1 Topics: Animals; Biological Availability; Chemistry, Pharmaceutical; Drug Design; Histamine Antagonists; Humans; Hypersensitivity; Inhibitory Concentration 50; Kinetics; Ligands; Mice; Models, Chemical; Models, Molecular; Molecular Conformation; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship; Time Factors	2012
2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor-H1/H4-receptor selectivity. Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2 Topics: Animals; Cell Line; Drug Inverse Agonism; Drug Partial Agonism; Histamine Agonists; Histamine Antagonists; Humans; Indoles; Ligands; Molecular Docking Simulation; Piperazines; Pyrimidines; Quinazolines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H4; Spodoptera	2016
Conformational Restriction and Enantioseparation Increase Potency and Selectivity of Cyanoguanidine-Type Histamine H4 Receptor Agonists. Journal of medicinal chemistry, 2016, Apr-14, Volume: 59, Issue:7 Topics: Animals; Guanidines; Guanosine 5'-O-(3-Thiotriphosphate); HEK293 Cells; Histamine Agonists; Humans; Imidazoles; Mice; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Protein Conformation; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Sf9 Cells; Spodoptera; Stereoisomerism; Structure-Activity Relationship	2016
Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus. The Journal of allergy and clinical immunology, 2007, Volume: 119, Issue:1 Topics: Animals; Disease Models, Animal; Edema; Female; Foot; Histamine; Histamine Agonists; Histamine Antagonists; Indoles; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Knockout; Piperazines; Pruritus; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H4	2007
Histamine downregulates monocyte CCL2 production through the histamine H4 receptor. The Journal of allergy and clinical immunology, 2007, Volume: 120, Issue:2 Topics: Calcium; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Down-Regulation; Histamine; Histamine Agonists; Humans; Imidazoles; Indoles; Interferon-gamma; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Matrix Metalloproteinase 8; Methylhistamines; Monocytes; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Thiourea; Up-Regulation	2007
Binding mode analysis and enrichment studies on homology models of the human histamine H4 receptor. European journal of medicinal chemistry, 2008, Volume: 43, Issue:5 Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Crystallography, X-Ray; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Indoles; Models, Molecular; Molecular Sequence Data; Piperazines; Protein Conformation; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Rhodopsin; Sequence Homology, Amino Acid	2008
Activation mechanism of the human histamine H4 receptor--an explicit membrane molecular dynamics simulation study. Journal of chemical information and modeling, 2008, Volume: 48, Issue:6 Topics: Binding Sites; Cell Membrane; Computer Simulation; Conserved Sequence; Drug Design; Extracellular Space; Histamine; Humans; Indoles; Intracellular Space; Ligands; Models, Molecular; Movement; Phosphatidylcholines; Piperazines; Protein Structure, Secondary; Protons; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Water	2008
Phenylalanine 169 in the second extracellular loop of the human histamine H4 receptor is responsible for the difference in agonist binding between human and mouse H4 receptors. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:1 Topics: Amino Acid Sequence; Animals; Cell Line; Histamine; Humans; Indoles; Mice; Molecular Sequence Data; Phenylalanine; Piperazines; Receptors, Adrenergic, beta-2; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Species Specificity	2008
The histamine H4 receptor antagonist JNJ7777120 induces increases in the histamine content of the rat conjunctiva. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2009, Volume: 58, Issue:6 Topics: Animals; Conjunctiva; Conjunctivitis; Histamine; Histamine Antagonists; Indoles; Male; p-Methoxy-N-methylphenethylamine; Piperazines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4	2009
Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist. The Journal of toxicological sciences, 2009, Volume: 34, Issue:4 Topics: Animals; Disease Models, Animal; Epidermis; Histamine; Histamine Antagonists; Humans; Indoles; Keratinocytes; Male; Mice; Mice, Inbred ICR; Piperazines; Pruritus; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Substance P	2009
Histamine stimulates human lung fibroblast migration. Molecular and cellular biochemistry, 2010, Volume: 337, Issue:1-2 Topics: Cell Migration Assays; Cell Movement; Cells, Cultured; Diphenhydramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Fibroblasts; Fibronectins; Histamine; Histamine Antagonists; Humans; Indoles; Lung; Piperazines; Ranitidine; Receptors, Histamine; Wound Healing	2010
The histamine H receptor as a new target for treatment of canine inflammatory skin diseases. Veterinary dermatology, 2009, Volume: 20, Issue:5-6 Topics: Animals; Calcium; Cell Line; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Female; Guanidines; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Indoles; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Mastocytoma; Mice; Mice, Inbred BALB C; Peptides; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Skin Diseases; Thiourea; Wasp Venoms	2009
Histamine H(4) receptor activation on human slan-dendritic cells down-regulates their pro-inflammatory capacity. Immunology, 2011, Volume: 132, Issue:1 Topics: Amino Sugars; Cytokines; Dendritic Cells; Dermatitis, Atopic; Flow Cytometry; Histamine; Humans; Indoles; Inflammation; Interferon-gamma; Lipopolysaccharides; Methylhistamines; Piperazines; Psoriasis; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2011
Histamine H(4) receptor antagonism inhibits allergen-specific T-cell responses mediated by human dendritic cells. European journal of pharmacology, 2011, Jan-25, Volume: 651, Issue:1-3 Topics: Adult; Allergens; Case-Control Studies; Dendritic Cells; Female; Gene Expression Regulation; Histamine; Humans; Hypersensitivity; Indoles; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Piperazines; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H4; T-Lymphocytes; Transcription, Genetic; Young Adult	2011
Histamine H₄ receptor activation enhances LPS-induced IL-6 production in mast cells via ERK and PI3K activation. European journal of immunology, 2011, Volume: 41, Issue:6 Topics: Animals; Bone Marrow; Cells, Cultured; Enzyme Activation; Histamine; Indoles; Inflammation; Interleukin-6; Lipopolysaccharides; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Signal Transduction	2011
Lack of preventing effect of systemically and topically administered histamine H(1) or H(4) receptor antagonists in a dog model of acute atopic dermatitis. Experimental dermatology, 2011, Volume: 20, Issue:7 Topics: Aging; Animals; Antigens, Dermatophagoides; Cetirizine; Dermatitis, Atopic; Dermatophagoides farinae; Disease Models, Animal; Dogs; Erythema; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Hydroxyzine; Indoles; Male; Permeability; Piperazines; Skin; Skin Absorption; Triamcinolone	2011
Role of H4 receptor in histamine-mediated responses in human melanoma. Melanoma research, 2011, Volume: 21, Issue:5 Topics: Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Guanidines; Histamine; Humans; Imidazoles; Immunohistochemistry; Indoles; Melanoma; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; RNA, Messenger; Skin Neoplasms; Thiourea	2011
Role of histamine and its receptor subtypes in stimulation of conjunctival goblet cell secretion. Investigative ophthalmology & visual science, 2012, May-17, Volume: 53, Issue:6 Topics: Animals; Blotting, Western; Cells, Cultured; Cimetidine; Conjunctiva; Conjunctivitis, Allergic; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Goblet Cells; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Indoles; Male; Methylhistamines; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Histamine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles	2012
The antagonism of histamine H1 and H4 receptors ameliorates chronic allergic dermatitis via anti-pruritic and anti-inflammatory effects in NC/Nga mice. Allergy, 2012, Volume: 67, Issue:8 Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Bone Marrow Cells; Chemokine CCL17; Chemokine CCL22; Cytokines; Dermatitis, Atopic; Dibenzoxepins; Disease Models, Animal; Down-Regulation; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine Release; Immunoglobulin E; Indoles; Male; Mast Cells; Mice; Olopatadine Hydrochloride; Picryl Chloride; Piperazines; Receptors, Histamine H1; Semaphorin-3A	2012
Expression of histamine receptor genes Hrh3 and Hrh4 in rat brain endothelial cells. British journal of pharmacology, 2013, Volume: 170, Issue:1 Topics: Animals; Blood-Brain Barrier; Brain; Cell Line; Dose-Response Relationship, Drug; Endothelial Cells; Histamine; Imidazoles; Indoles; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Piperazines; Piperidines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2013
Profiling of histamine H4 receptor agonists in native human monocytes. British journal of pharmacology, 2013, Volume: 170, Issue:1 Topics: Cell Line; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Indoles; Interleukin-12; Ligands; Monocytes; Piperazines; Ranitidine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H2; Receptors, Histamine H4; Transfection	2013
Histamine induces proliferation in keratinocytes from patients with atopic dermatitis through the histamine 4 receptor. The Journal of allergy and clinical immunology, 2013, Volume: 132, Issue:6 Topics: Animals; Cell Line; Cell Proliferation; Dermatitis, Atopic; Female; Gene Expression Regulation; Histamine; Histamine Antagonists; Humans; Indoles; Keratinocytes; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Peptidoglycan; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4	2013
Increased expression of the histamine H4 receptor following differentiation and mediation of the H4 receptor on interleukin-8 mRNA expression in HaCaT keratinocytes. Experimental dermatology, 2014, Volume: 23, Issue:2 Topics: Cell Differentiation; Cell Line; Gene Expression Regulation; Histamine; Humans; Indoles; Interleukin-8; Keratinocytes; Piperazines; Protein Precursors; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; RNA, Messenger; Tumor Necrosis Factor-alpha	2014
Histamine H4 and H1 receptors contribute to postinflammatory visceral hypersensitivity. Gut, 2014, Volume: 63, Issue:12 Topics: Animals; Cetirizine; Colitis; Colonoscopy; Convalescence; Disease Models, Animal; Histamine; Histamine H1 Antagonists, Non-Sedating; Histamine Release; Hypersensitivity; Indoles; Intestinal Mucosa; Male; Mast Cells; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H4; Regeneration; Trinitrobenzenesulfonic Acid	2014
The histamine H4 receptor is a potent inhibitor of adhesion-dependent degranulation in human neutrophils. Journal of leukocyte biology, 2014, Volume: 96, Issue:3 Topics: Cell Adhesion; Cell Degranulation; Cell Line, Tumor; Cell Shape; Cells, Cultured; Cytochalasin B; Fibrinogen; Histamine; Humans; Indoles; Leukemia, Promyelocytic, Acute; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen; MAP Kinase Signaling System; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oximes; p38 Mitogen-Activated Protein Kinases; Piperazines; Piperidines; Protein Conformation; Pyridines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; RNA, Messenger	2014
Histamine H3 and H4 receptor ligands modify vascular histamine levels in normal and arthritic large blood vessels in vivo. Inflammation, 2015, Volume: 38, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Aorta; Arthritis, Experimental; Azepines; Dimethindene; Endothelium; Freund's Adjuvant; Histamine; Histamine H1 Antagonists; Histamine H3 Antagonists; Indoles; Inflammation; Male; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Vena Cava, Inferior	2015
Histamine receptor expression in human renal tubules: a comparative pharmacological evaluation. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2015, Volume: 64, Issue:3-4 Topics: Benzazepines; Cell Line; Chlorpheniramine; Dose-Response Relationship, Drug; Epithelial Cells; Histamine; Histamine Antagonists; Humans; In Vitro Techniques; Indoles; Kidney Tubules; Niacinamide; Piperazines; Ranitidine; Receptors, Histamine; Second Messenger Systems	2015
Histamine reduces boron neutron capture therapy-induced mucositis in an oral precancer model. Oral diseases, 2015, Volume: 21, Issue:6 Topics: Animals; Boron Neutron Capture Therapy; Cricetinae; Disease Models, Animal; Histamine; Indoles; Mouth Neoplasms; Piperazines; Precancerous Conditions; Radiation Injuries, Experimental; Radiation-Protective Agents; Stomatitis	2015
Stimulatory effects of histamine on migration of nasal fibroblasts. International forum of allergy & rhinology, 2015, Volume: 5, Issue:10 Topics: Cell Adhesion; Cell Movement; Cells, Cultured; Cytoskeleton; Estrenes; Fibroblasts; Histamine; Humans; Immunization; Indoles; Pertussis Toxin; Piperazines; Pyrrolidinones; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Signal Transduction; Turbinates	2015
In vitro study of histamine and histamine receptor ligands influence on the adhesion of purified human eosinophils to endothelium. European journal of pharmacology, 2016, Apr-15, Volume: 777 Topics: Cell Adhesion; Cell Communication; Cell Line; Cell Separation; Cell Survival; Drug Inverse Agonism; Endothelium; Eosinophils; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Indoles; Ligands; Methylhistamines; N-Formylmethionine Leucyl-Phenylalanine; Piperazines; Piperidines; Receptors, Histamine	2016
Allergic inflammation is augmented via histamine H4 receptor activation: The role of natural killer cells in vitro and in vivo. Journal of dermatological science, 2016, Volume: 83, Issue:2 Topics: Animals; Chemokine CCL17; Chemotaxis; Coculture Techniques; Dendritic Cells; Dermatitis, Atopic; Disease Models, Animal; Female; Histamine; Humans; Indoles; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Mice, Knockout; Ovalbumin; Piperazines; Pyrimidines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Skin; Toluene 2,4-Diisocyanate	2016
Preliminary study of histamine H Journal of dermatological science, 2017, Volume: 88, Issue:1 Topics: Cell Separation; Dermatitis, Seborrheic; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Histamine; Humans; Indoles; Interleukin-17; Interleukin-23; Piperazines; Psoriasis; Receptors, Histamine H4; Recombinant Proteins; Signal Transduction; Th17 Cells	2017
Histamine stimulates secretion of extracellular vesicles with nucleotidase activity in rat submandibular gland. Archives of oral biology, 2018, Volume: 85 Topics: Animals; Extracellular Vesicles; Histamine; In Vitro Techniques; Indoles; Male; Microscopy, Electron, Transmission; Nucleotidases; Piperazines; Rats; Rats, Wistar; Submandibular Gland	2018
Silencing of H4R inhibits the production of IL-1β through SAPK/JNK signaling in human mast cells. Journal of receptor and signal transduction research, 2018, Volume: 38, Issue:3 Topics: Calcium; Cell Line; Gene Expression Regulation; Gene Silencing; Histamine; Humans; Indoles; Interleukin-1beta; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mast Cells; Methylhistamines; Piperazines; Pyrilamine; Receptors, Histamine H4; RNA, Small Interfering	2018
Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model. Brain, behavior, and immunity, 2019, Volume: 76 Topics: alpha-Synuclein; Animals; Behavior, Animal; Brain; Corpus Striatum; Disease Models, Animal; Disease Progression; Dopaminergic Neurons; Histamine; Indoles; Inflammation; Male; Microglia; Nerve Degeneration; Parkinson Disease; Parkinsonian Disorders; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H4; Rotenone	2019
Study of the antitumour effects and the modulation of immune response by histamine in breast cancer. British journal of cancer, 2020, Volume: 122, Issue:3 Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Databases, Factual; Female; Histamine; Histamine Agonists; Histamine Antagonists; Histidine Decarboxylase; Humans; Indoles; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Inbred BALB C; Mice, Knockout; Oximes; Piperazines; Prognosis; Receptors, Histamine H4; Triple Negative Breast Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays	2020