histamine and clobenpropit

histamine has been researched along with clobenpropit in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (10.71)18.2507
2000's39 (69.64)29.6817
2010's8 (14.29)24.3611
2020's3 (5.36)2.80

Authors

AuthorsStudies
Christiaans, JA; Gynther, J; Kotisaari, S; Kovalainen, JT; Laitinen, JT; Männistö, PT; Tuomisto, L1
Chang, H; Erlander, MG; Lovenberg, TW; Pyati, J; Wilson, SJ1
Arrang, JM; Ganellin, CR; Gbahou, F; Ligneau, X; Morisset, S; Schunack, W; Schwartz, JC; Stark, H; Tardivel-Lacombe, J1
Arrang, JM; Gbahou, F; Héron, A; Ligneau, X; Morisset, S; Sasse, A; Schwartz, JC; Tardivel-Lacombe, J1
Blevitt, J; Carruthers, N; Chai, W; Hofstra, CL; Jiang, X; Li, X; Liu, C; Lovenberg, TW; Ma, X; Pyati, J; Wilson, SJ1
Anthes, JC; Bayne, M; Behan, J; Gonsiorek, W; Greene, J; Greenfeder, SA; Gustafson, EL; Hedrick, JA; Hipkin, RW; Laz, TM; Monsma, FJ; Morse, KL; Qiao, X; Shin, N; Umland, S; Wan, Y; Wang, S; West, RE1
Audinot, V; Beauverger, P; Boutin, JA; Cogé, F; Galizzi, JP; Guénin, SP; Macia, C; Nagel, N; Ouvry, C; Renouard-Try, A; Rique, H1
Kuei, C; Liu, C; Lovenberg, TW; Wilson, SJ1
Hastrup, S; Rimvall, K; Wulff, BS1
Chen, J; Liu, C; Lovenberg, TW1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM1
Falus, A; Jelinek, I; Keseru, GM; Kiss, B; Kiss, R; Könczöl, A; László, V; Noszál, B; Szalai, F1
Ito, S; Mitobe, Y; Mizutani, T; Nagase, T; Sato, N; Tokita, S1
de Esch, IJ; de Graaf, C; Istyastono, EP; Kooistra, AJ; Leurs, R; Lim, HD; Nijmeijer, S; Roumen, L; van de Stolpe, A; Vischer, HF1
Grätz, L; Humphrys, LJ; Işbilir, A; Lohse, MJ; Möller, J; Nagl, M; Pockes, S; Rosier, N; Schihada, H; Seibel, U1
Buczko, W; Godlewski, G; Malinowska, B; Schlicker, E1
Hemedah, M; Mitchelson, F1
Bacciottini, L; Blandina, P; Cecchi, M; Giorgetti, M; Giovannini, MG1
Aarden, LA; Alewijnse, AE; Boeije, LC; de Groot, ER; Leurs, R; Snijders, A; van der Pouw Kraan, TC1
Schlicker, E; Werthwein, S; Zentner, J1
de Wildt, DJ; Hendriksen, CF; van de Kuil, A; van den Hout, JW; Vleeming, W1
Chen, Z; Fujii, Y; Ishizawa, K; Kamei, C; Okuma, C; Sugimoto, Y1
Aceves, J; Arias-Montaño, JA; Floran, B; Garcia, M; Young, JM1
Chen, Z1
Barnes, W; Boyd, D; Hough, L1
Blanco, I; Gomez-Ramirez, J; Ortiz, J1
Chen, Z; Hu, WW; Huang, YW; Wei, EQ; Yanai, K; Zhang, LS1
Buckland, KF; Conroy, DM; Williams, TJ1
Fujii, Y; Hossen, MA; Kamei, C; Kayasuga, R; Sugimoto, Y1
Chen, Z; Hu, WW; Jin, CL; Shen, HQ; Zhang, LS; Zhao, MH1
Fu, YL; He, SH; Xie, H1
Djahanguiri, B; Khalilzadeh, A; Zarrindast, MR1
Blanks, AM; Lee, K; Renaud, LP; Spanswick, D; Whyment, AD1
Eckman, JR; Wagner, MC; Wick, TM1
Holopainen, IE; Kukko-Lukjanov, TK; Michelsen, KA; Panula, P; Soini, S; Taira, T1
Carr, TL; Cassar, S; Esbenshade, TA; Faghih, R; Hancock, AA; Krueger, KM; Miller, TR; Sharma, R; Surber, BW; Witte, DG; Yao, BB1
Blanco, I; de Esch, I; Gómez-Ramírez, J; Moreno-Delgado, D; Ortiz, J; Torrent, A1
Arias-Montaño, JA; Garduño-Torres, B; Gutiérrez, R; Treviño, M1
Chen, Z; Dai, HB; Fu, QL; Shen, Y1
Chazot, P; Dijkstra, D; Gutzmer, R; Leurs, R; Shenton, FC; Stark, H; Werfel, T1
Brzozowski, T; Gaca, P; Hahn, EG; Konturek, PC; Konturek, SJ; Pawlik, M; Raithel, M1
Bergoc, R; Crescenti, E; Cricco, G; Croci, M; Martin, G; Massari, N; Medina, V; Mohamad, N; Nuñez, M; Rivera, E; Sanchez-Jiménez, F1
Hatano, K; Ishizuka, T; Murotani, T; Yamatodani, A1
Kamei, C; Kuyama, S; Ogawa, M; Yokota, E1
Bäumer, W; Chazot, P; Dijkstra, D; Gutzmer, R; Kietzmann, M; Stark, H; Wendorff, S; Werfel, T1
Barrett, P; Ebling, FJ; Enright, RA; Jethwa, PH; Murphy, M; Turnbull, Y; Warner, A1
Khodarahmi, P; Oryan, S; Rezayof, A; Zarrindast, MR1
Bäumer, W; Kietzmann, M; Leurs, R; Rossbach, K; Sander, K; Stark, H1
Khanam, R; Manocha, A; Uma Devi, P; Vohora, D1
Bertron, AF; Dy, M; Schneider, E1
Bergoc, RM; Cricco, GP; Croci, M; Martinel Lamas, DJ; Massari, NA; Medina, VA; Rivera, ES; Sambuco, L1
Akhtar, M; Goswami, D; Jahan, K; Mahmood, D1
Bachelerie, F; Chauveau, L; Cutolo, P; Davidson, S; Durroux, T; Dutrieux, J; Dy, M; Herbeuval, JP; Manoury, B; McCort-Tranchepain, I; Münch, J; Nisole, S; Pietrancosta, N; Schwartz, O; Scott-Algara, D; Smith, N; Wack, A; Zirafi, O1
An, S; Chen, LY; Guo, XX; Hao, Q; Liu, Y; Ma, L; Pediani, JD; Tang, M; Ward, RJ; Wu, N; Xu, TR; Yang, Y; Zeng, H1
Bryukhovetskiy, I; Buzoianu, AD; Castellani, RJ; Lafuente, JV; Manzhulo, I; Menon, PK; Muresanu, DF; Nozari, A; Patnaik, R; Sahib, S; Sharma, A; Sharma, HS; Skaper, SD; Tian, ZR; Wiklund, L1
Buzoianu, AD; Chen, L; Feng, L; Huang, H; Lafuente, JV; Muresanu, DF; Nozari, A; Sharma, A; Sharma, HS; Tian, ZR; Wiklund, L1

Reviews

3 review(s) available for histamine and clobenpropit

ArticleYear
Modulation of hematopoiesis through histamine receptor signaling.
    Frontiers in bioscience (Scholar edition), 2011, 01-01, Volume: 3, Issue:2

    Topics: Animals; Cell Cycle; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p21; Hematopoiesis; Hematopoietic Stem Cells; Histamine; Humans; Imidazoles; Mice; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Signal Transduction; Thiourea

2011
Histamine H3 and H4 receptors modulate Parkinson's disease induced brain pathology. Neuroprotective effects of nanowired BF-2649 and clobenpropit with anti-histamine-antibody therapy.
    Progress in brain research, 2021, Volume: 266

    Topics: Corpus Striatum; Histamine; Humans; Imidazoles; Neuroprotective Agents; Parkinson Disease; Receptors, Histamine H4; Thiourea

2021
Nanodelivery of Histamine H3/H4 Receptor Modulators BF-2649 and Clobenpropit with Antibodies to Amyloid Beta Peptide in Combination with Alpha Synuclein Reduces Brain Pathology in Parkinson's Disease.
    Advances in neurobiology, 2023, Volume: 32

    Topics: alpha-Synuclein; Amyloid beta-Peptides; Antibodies, Monoclonal; Brain; Drug Inverse Agonism; Histamine; Humans; Nanoparticle Drug Delivery System; Parkinson Disease; Receptors, Histamine H3; Receptors, Histamine H4

2023

Other Studies

53 other study(ies) available for histamine and clobenpropit

ArticleYear
Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.
    Journal of medicinal chemistry, 1999, Apr-08, Volume: 42, Issue:7

    Topics: Animals; Autoradiography; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Histamine Agonists; Histamine Antagonists; Imidazoles; In Vitro Techniques; Ligands; Male; Propylamines; Rats; Rats, Wistar; Receptors, Histamine H3; Stereoisomerism; Structure-Activity Relationship

1999
Cloning of rat histamine H(3) receptor reveals distinct species pharmacological profiles.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Animals; Cloning, Molecular; Dose-Response Relationship, Drug; Humans; Methylhistamines; Molecular Sequence Data; Rats; Receptors, Histamine H3; Recombinant Proteins; RNA, Messenger

2000
Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain.
    British journal of pharmacology, 2000, Volume: 131, Issue:7

    Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Binding, Competitive; COS Cells; DNA, Complementary; Dose-Response Relationship, Drug; Histamine Antagonists; Humans; Imidazoles; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Piperidines; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, Histamine H3; Sequence Alignment; Sequence Homology, Amino Acid; Tritium

2000
The rat H3 receptor: gene organization and multiple isoforms.
    Biochemical and biophysical research communications, 2001, Jan-12, Volume: 280, Issue:1

    Topics: Animals; Autoradiography; Brain; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Frameshift Mutation; Genetic Variation; In Situ Hybridization; Introns; Iodine Radioisotopes; Organ Specificity; Protein Isoforms; Radioligand Assay; Rats; Receptors, Histamine H3; Recombinant Proteins; Sequence Deletion; Transcription, Genetic; Transfection

2001
Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow.
    Molecular pharmacology, 2001, Volume: 59, Issue:3

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Bone Marrow; Cloning, Molecular; Histamine; Humans; Methylhistamines; Molecular Sequence Data; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; RNA, Messenger; Sequence Homology, Amino Acid; Tissue Distribution; Tritium

2001
Cloning and characterization of a novel human histamine receptor.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3

    Topics: Amino Acid Sequence; Cells, Cultured; Cloning, Molecular; Histamine; Histamine Agonists; Humans; Imidazoles; Molecular Sequence Data; Radioligand Assay; Receptors, Histamine; Receptors, Histamine H3; RNA, Messenger; Sequence Homology, Amino Acid; Thiourea; Tissue Distribution; Transfection

2001
Genomic organization and characterization of splice variants of the human histamine H3 receptor.
    The Biochemical journal, 2001, Apr-15, Volume: 355, Issue:Pt 2

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Calcium; CHO Cells; Cloning, Molecular; Cricetinae; DNA, Complementary; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Microscopy, Fluorescence; Molecular Sequence Data; Protein Binding; Receptors, Histamine H3; Sequence Homology, Amino Acid; Sulfur Radioisotopes

2001
Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:1

    Topics: Amino Acid Sequence; Animals; Calcium; Cell Line; Cloning, Molecular; COS Cells; Cyclic AMP; DNA Fragmentation; Guinea Pigs; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity; Transfection

2001
Characteristics of recombinantly expressed rat and human histamine H3 receptors.
    European journal of pharmacology, 2002, Oct-18, Volume: 453, Issue:1

    Topics: Animals; Cell Line; Cloning, Molecular; Histamine Agonists; Histamine Antagonists; Humans; Rats; Receptors, Histamine; Receptors, Histamine H3; Recombination, Genetic

2002
Molecular and pharmacological characterization of the mouse histamine H3 receptor.
    European journal of pharmacology, 2003, Apr-25, Volume: 467, Issue:1-3

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Brain; Calcium; Cells, Cultured; Chlorocebus aethiops; Cloning, Molecular; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Mice; Molecular Sequence Data; Rats; Receptors, Histamine H3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology; Thiourea

2003
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4

2005
Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening.
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Binding, Competitive; Cell Line, Tumor; Databases, Factual; Histamine Antagonists; Humans; Ligands; Models, Molecular; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship

2008
Development of a selective and potent radioactive ligand for histamine H(3) receptors: A compound potentially useful for receptor occupancy studies.
    Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Brain; Chemistry, Pharmaceutical; Drug Design; Humans; Kinetics; Ligands; Mice; Models, Chemical; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Histamine H3; Structure-Activity Relationship

2009
Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies.
    Journal of medicinal chemistry, 2011, Dec-08, Volume: 54, Issue:23

    Topics: Cell Line, Tumor; Histamine Antagonists; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Quantitative Structure-Activity Relationship; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Stereoisomerism; Thiourea

2011
A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H
    Journal of medicinal chemistry, 2021, 08-12, Volume: 64, Issue:15

    Topics: Binding Sites; Bioluminescence Resonance Energy Transfer Techniques; Dose-Response Relationship, Drug; Fluorescent Dyes; HEK293 Cells; Histamine H3 Antagonists; Humans; Ligands; Molecular Structure; Receptors, Histamine H3; Single Molecule Imaging; Structure-Activity Relationship

2021
Inhibitory H3 receptors on sympathetic nerves of the pithed rat: activation by endogenous histamine and operation in spontaneously hypertensive rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:2

    Topics: Adrenergic Fibers; Animals; Blood Pressure; Decerebrate State; Electric Stimulation; Histamine; Histamine Agonists; Histamine Antagonists; Hypertension; Imidazoles; Male; Methylhistamines; Piperidines; Pyrimethamine; Rats; Rats, Wistar; Receptors, Histamine H3; Thiourea; Vagotomy; Vascular Resistance

1997
Comparison of the effects of histamine and N(alpha)-methylhistamine on neuronal function in the guinea-pig oesophagus and ileum.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:12

    Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Esophagus; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; Imidazoles; In Vitro Techniques; Methylhistamines; Muscle, Skeletal; Muscle, Smooth; Neurons; Neurons, Afferent; Pyrilamine; Receptors, Cholinergic; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Tetrodotoxin; Thiourea; Vagus Nerve

1997
Increase of acetylcholine release from cortex of freely moving rats by administration of histamine into the nucleus basalis magnocellularis.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47 Suppl 1

    Topics: Acetylcholine; Animals; Cerebral Cortex; Cimetidine; Electroencephalography; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Imidazoles; Male; Neurons; Rats; Rats, Wistar; Substantia Innominata; Telencephalon; Thiourea; Triprolidine

1998
Histamine inhibits the production of interleukin-12 through interaction with H2 receptors.
    The Journal of clinical investigation, 1998, Nov-15, Volume: 102, Issue:10

    Topics: Dinoprostone; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Interleukin-12; Interleukins; Monocytes; Ranitidine; Receptors, Histamine H2; RNA, Messenger; Thiourea; Triprolidine

1998
Histamine H3 receptor-mediated inhibition of noradrenaline release in the human brain.
    Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:1

    Topics: Animals; Brain; Cerebral Cortex; Dimethindene; Electric Stimulation; Hippocampus; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Male; Mice; Mice, Inbred Strains; Norepinephrine; Piperidines; Ranitidine; Receptors, Histamine H3; Thiourea; Tritium

1999
Mepyramine but not cimetidine or clobenpropit blocks pertussis toxin-induced histamine sensitization in rats.
    British journal of pharmacology, 2000, Volume: 129, Issue:8

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Cimetidine; Drug Interactions; Histamine; Histamine Antagonists; Imidazoles; Male; Pertussis Toxin; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine; Thiourea; Virulence Factors, Bordetella

2000
Participation of GABAergic and histaminergic systems in inhibiting amygdaloid kindled seizures.
    Japanese journal of pharmacology, 2000, Volume: 82, Issue:1

    Topics: Amygdala; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Histamine; Imidazoles; Kindling, Neurologic; Male; Muscimol; Rats; Rats, Wistar; Seizures; Thiourea; Valproic Acid

2000
Histamine H(3) receptor-mediated inhibition of depolarization-induced, dopamine D(1) receptor-dependent release of [(3)H]-gamma-aminobutryic acid from rat striatal slices.
    British journal of pharmacology, 2001, Volume: 133, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Calcium; Dopamine; Dopamine D2 Receptor Antagonists; gamma-Aminobutyric Acid; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; In Vitro Techniques; Male; Membrane Potentials; Neostriatum; Piperidines; Potassium; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Histamine H3; Reserpine; Sulpiride; Thiourea

2001
Effect of histamine H3-receptor antagonist clobenpropit on spatial memory of radial maze performance in rats.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:10

    Topics: Animals; Brain; Histamine; Histamine Antagonists; Imidazoles; Injections, Intraventricular; Male; Maze Learning; Memory Disorders; Rats; Rats, Wistar; Scopolamine; Thiourea

2000
Dynamics of histamine H(3) receptor antagonists on brain histamine metabolism: do all histamine H(3) receptor antagonists act at a single site?
    European journal of pharmacology, 2001, Nov-16, Volume: 431, Issue:2

    Topics: Analysis of Variance; Animals; Binding Sites; Brain; Histamine; Histamine Antagonists; Imidazoles; Male; Methylhistamines; Mice; Pargyline; Piperidines; Rats; Receptors, Histamine H3; Thiourea

2001
Presynaptic H3 autoreceptors modulate histamine synthesis through cAMP pathway.
    Molecular pharmacology, 2002, Volume: 61, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Bucladesine; Colforsin; Cyclic AMP; Drug Interactions; Histamine; Imidazoles; In Vitro Techniques; Male; Piperidines; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Thionucleotides; Thiourea

2002
Effects of endogenous histamine on seizure development of pentylenetetrazole-induced kindling in rats.
    Pharmacology, 2003, Volume: 69, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Histamine; Histamine Release; Histidine; Imidazoles; Injections, Intraventricular; Kindling, Neurologic; Male; Methylhistidines; Pentylenetetrazole; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Seizures; Thiourea

2003
Histamine induces cytoskeletal changes in human eosinophils via the H(4) receptor.
    British journal of pharmacology, 2003, Volume: 140, Issue:6

    Topics: Actins; Calcium; CD11b Antigen; Cell Size; Chemokine CCL11; Chemokines, CC; Chemotaxis; Clozapine; Cytoskeleton; Dose-Response Relationship, Drug; Eosinophils; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Pertussis Toxin; Piperidines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Thiourea; Up-Regulation

2003
Histamine H3 receptors regulate vascular permeability changes in the skin of mast cell-deficient mice.
    International immunopharmacology, 2003, Volume: 3, Issue:12

    Topics: Animals; Capillary Permeability; Chlorpheniramine; Diphenhydramine; Evans Blue; Female; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Injections, Intradermal; Injections, Intravenous; Isothiuronium; Mast Cells; Mice; Mice, Mutant Strains; Piperidines; Receptors, Histamine H3; Skin; Thiourea; Tryptophan

2003
[Mechanisms of the effect of brain histamine on chronic epilepsy induced by pentylenetetrazole].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2004, Volume: 33, Issue:3

    Topics: Animals; Brain; Chronic Disease; Dose-Response Relationship, Drug; Epilepsy; Histamine; Histidine; Imidazoles; Male; Pentylenetetrazole; Piperidines; Rats; Rats, Sprague-Dawley; Thiourea

2004
Inhibition of tryptase release from human colon mast cells by histamine receptor antagonists.
    Asian Pacific journal of allergy and immunology, 2005, Volume: 23, Issue:1

    Topics: Calcimycin; Cells, Cultured; Cimetidine; Colon; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Ionophores; Mast Cells; Serine Endopeptidases; Serine Proteinase Inhibitors; Terfenadine; Thiourea; Tryptases

2005
Effects of intracerebroventricular administration of ultra low doses of histaminergic drugs on morphine state-dependent memory of passive avoidance in mice.
    Behavioural brain research, 2006, Jan-06, Volume: 166, Issue:1

    Topics: Analgesics, Opioid; Animals; Avoidance Learning; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histamine Agents; Imidazoles; Injections, Intraventricular; Male; Memory; Mice; Morphine; Morphine Dependence; Pyrilamine; Reaction Time; Thiourea

2006
Histamine excites neonatal rat sympathetic preganglionic neurons in vitro via activation of H1 receptors.
    Journal of neurophysiology, 2006, Volume: 95, Issue:4

    Topics: Action Potentials; Animals; Animals, Newborn; Autonomic Fibers, Preganglionic; Barium; Dimaprit; Female; Ganglia, Sympathetic; Histamine; Histamine Agonists; Histamine H1 Antagonists; Imidazoles; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium; Rats; Rats, Inbred WKY; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiourea; Triprolidine

2006
Histamine increases sickle erythrocyte adherence to endothelium.
    British journal of haematology, 2006, Volume: 132, Issue:4

    Topics: Analysis of Variance; Anemia, Sickle Cell; Cell Adhesion; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Erythrocytes; Famotidine; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Methylhistamines; P-Selectin; Piperidines; Pyrilamine; Stimulation, Chemical; Thiazoles; Thiourea; Venules

2006
Histaminergic neurons protect the developing hippocampus from kainic acid-induced neuronal damage in an organotypic coculture system.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Jan-25, Volume: 26, Issue:4

    Topics: Animals; Cell Death; Cells, Cultured; Coculture Techniques; Convulsants; Hippocampus; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Hypothalamus, Anterior; Hypothalamus, Posterior; Imidazoles; Kainic Acid; Methylhistidines; Microscopy, Confocal; Neurons; Neuroprotective Agents; Organ Culture Techniques; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Receptors, Histamine H3; Thiourea; Triprolidine

2006
Detection of multiple H3 receptor affinity states utilizing [3H]A-349821, a novel, selective, non-imidazole histamine H3 receptor inverse agonist radioligand.
    British journal of pharmacology, 2006, Volume: 148, Issue:5

    Topics: Animals; Binding, Competitive; Biphenyl Compounds; Cells, Cultured; Guanosine Diphosphate; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Methylhistamines; Models, Biological; Protein Binding; Radioligand Assay; Rats; Receptors, Histamine H3; Thiourea

2006
Constitutive activity of H3 autoreceptors modulates histamine synthesis in rat brain through the cAMP/PKA pathway.
    Neuropharmacology, 2006, Volume: 51, Issue:3

    Topics: Animals; Biphenyl Compounds; Brain; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; In Vitro Techniques; Male; Models, Biological; Nitriles; Piperidines; Potassium; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Thiourea

2006
Pre-synaptic histamine H3 receptors regulate glutamate, but not GABA release in rat thalamus.
    Neuropharmacology, 2007, Volume: 52, Issue:2

    Topics: 4-Aminopyridine; Animals; Dose-Response Relationship, Drug; Drug Interactions; Evoked Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Histamine; Histamine Antagonists; Imidazoles; In Vitro Techniques; Male; Methylhistamines; Pertussis Toxin; Presynaptic Terminals; Protein Binding; Rats; Rats, Wistar; Receptors, Histamine H3; Synaptosomes; Thalamus; Thiourea; Tritium

2007
[Reversing effect of histamine on neurotoxicity induced by beta-amyloid1-42].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2007, Volume: 36, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Histamine H2 Antagonists; Histamine H3 Antagonists; Imidazoles; Neuroprotective Agents; PC12 Cells; Phenoxypropanolamines; Piperidines; Rats; Receptors, Histamine H2; Receptors, Histamine H3; Thiourea

2007
Histamine downregulates monocyte CCL2 production through the histamine H4 receptor.
    The Journal of allergy and clinical immunology, 2007, Volume: 120, Issue:2

    Topics: Calcium; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Down-Regulation; Histamine; Histamine Agonists; Humans; Imidazoles; Indoles; Interferon-gamma; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Matrix Metalloproteinase 8; Methylhistamines; Monocytes; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Thiourea; Up-Regulation

2007
Role of histamine in ghrelin-induced gastroprotection against acute gastric lesions.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2007, Volume: 56 Suppl 1

    Topics: Animals; Anti-Ulcer Agents; Cytoprotection; Ethanol; Gastric Mucosa; Ghrelin; Histamine; Histamine Antagonists; Imidazoles; Male; Peptide Hormones; Ranitidine; Rats; Rats, Wistar; Regional Blood Flow; Thiourea

2007
The role of histamine in human mammary carcinogenesis: H3 and H4 receptors as potential therapeutic targets for breast cancer treatment.
    Cancer biology & therapy, 2008, Volume: 7, Issue:1

    Topics: Adult; Aged; Breast; Breast Neoplasms; Cell Movement; Cell Proliferation; Female; Histamine; Histidine Decarboxylase; Humans; Imidazoles; Middle Aged; Proliferating Cell Nuclear Antigen; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Thiourea

2008
Comparison of the effect of an H(3)-inverse agonist on energy intake and hypothalamic histamine release in normal mice and leptin resistant mice with high fat diet-induced obesity.
    Behavioural brain research, 2008, Apr-09, Volume: 188, Issue:2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Body Weight; Chromatography, High Pressure Liquid; Electrochemistry; Energy Intake; Fats; Histamine; Histamine H3 Antagonists; Hypothalamus; Imidazoles; Leptin; Male; Mice; Mice, Inbred C57BL; Microdialysis; Obesity; Thiourea; Time Factors

2008
Substance P is involved in the effect of histamine H3 receptor agonist, Sch 50971 on nasal allergic symptoms in mice.
    International immunopharmacology, 2008, Volume: 8, Issue:8

    Topics: Animals; Capsaicin; Cetirizine; Disease Models, Animal; Female; Histamine; Histamine Agonists; Histamine H1 Antagonists, Non-Sedating; Imidazoles; Mice; Mice, Inbred BALB C; Ovalbumin; Piperidines; Pyrrolidines; Receptors, Histamine H3; Rhinitis, Allergic, Perennial; Substance P; Thiourea

2008
Histamine H4 receptors modulate dendritic cell migration through skin--immunomodulatory role of histamine.
    Allergy, 2008, Volume: 63, Issue:10

    Topics: Animals; Cell Movement; Chemotaxis, Leukocyte; Dendritic Cells; Female; Guinea Pigs; Histamine; Histamine H3 Antagonists; Imidazoles; Immunologic Factors; Injections, Intradermal; Mice; Mice, Inbred BALB C; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Skin; Thiourea

2008
The role of histamine 3 receptors in the control of food intake in a seasonal model of obesity: the Siberian hamster.
    Behavioural pharmacology, 2009, Volume: 20, Issue:2

    Topics: Animals; Body Temperature; Cell Line, Transformed; Cricetinae; Disease Models, Animal; Eating; Histamine; Imidazoles; Injections, Intraventricular; Motor Activity; Obesity; Phodopus; Photoperiod; Piperidines; Receptors, Histamine H3; Seasons; Thiourea; Transfection

2009
Withdrawal from repeated administration of morphine alters histamine-induced anxiogenic effects produced by intra-ventral hippocampal microinjection.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:6

    Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Hippocampus; Histamine; Histamine Antagonists; Imidazoles; Male; Microinjections; Morphine; Motor Activity; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Thiourea

2010
The histamine H receptor as a new target for treatment of canine inflammatory skin diseases.
    Veterinary dermatology, 2009, Volume: 20, Issue:5-6

    Topics: Animals; Calcium; Cell Line; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Female; Guanidines; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Indoles; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Mastocytoma; Mice; Mice, Inbred BALB C; Peptides; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Skin Diseases; Thiourea; Wasp Venoms

2009
Beneficial interaction between clobenpropit and pyridoxine in prevention of electroshock-induced seizures in mice: lack of histaminergic mechanisms.
    Human & experimental toxicology, 2011, Volume: 30, Issue:1

    Topics: Animals; Anticonvulsants; Brain; Drug Interactions; Electroshock; Female; Histamine; Histamine H3 Antagonists; Histidine Decarboxylase; Imidazoles; Male; Mice; Pyridoxine; Seizures; Thiourea

2011
Role of H4 receptor in histamine-mediated responses in human melanoma.
    Melanoma research, 2011, Volume: 21, Issue:5

    Topics: Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Guanidines; Histamine; Humans; Imidazoles; Immunohistochemistry; Indoles; Melanoma; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; RNA, Messenger; Skin Neoplasms; Thiourea

2011
Histamine H3 receptor antagonists display antischizophrenic activities in rats treated with MK-801.
    Journal of basic and clinical physiology and pharmacology, 2016, Sep-01, Volume: 27, Issue:5

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Histamine; Histamine H3 Antagonists; Imidazoles; Methylhistamines; Motor Activity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Thiourea

2016
Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement.
    Nature communications, 2017, 02-09, Volume: 8

    Topics: Amines; Ammonium Compounds; Animals; Dendritic Cells; Histamine; HIV; Humans; Imidazoles; Interferon Type I; Mice; Orthomyxoviridae; Receptors, CXCR4; Receptors, Histamine; Thiourea; TNF-Related Apoptosis-Inducing Ligand

2017
Visualization of the activation of the histamine H3 receptor (H3R) using novel fluorescence resonance energy transfer biosensors and their potential application to the study of H3R pharmacology.
    The FEBS journal, 2018, Volume: 285, Issue:12

    Topics: Bacterial Proteins; Biosensing Techniques; Cyclic AMP; Fluorescence Resonance Energy Transfer; Gene Expression; Green Fluorescent Proteins; HEK293 Cells; Histamine; Histamine Agonists; Histamine H3 Antagonists; Humans; Imidazoles; Kinetics; Luminescent Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Plasmids; Receptors, Histamine H3; Thiourea; Transfection; Tritium

2018