histamine has been researched along with clobenpropit in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (10.71) | 18.2507 |
| 2000's | 39 (69.64) | 29.6817 |
| 2010's | 8 (14.29) | 24.3611 |
| 2020's | 3 (5.36) | 2.80 |
| Authors | Studies |
|---|---|
| Christiaans, JA; Gynther, J; Kotisaari, S; Kovalainen, JT; Laitinen, JT; Männistö, PT; Tuomisto, L | 1 |
| Chang, H; Erlander, MG; Lovenberg, TW; Pyati, J; Wilson, SJ | 1 |
| Arrang, JM; Ganellin, CR; Gbahou, F; Ligneau, X; Morisset, S; Schunack, W; Schwartz, JC; Stark, H; Tardivel-Lacombe, J | 1 |
| Arrang, JM; Gbahou, F; Héron, A; Ligneau, X; Morisset, S; Sasse, A; Schwartz, JC; Tardivel-Lacombe, J | 1 |
| Blevitt, J; Carruthers, N; Chai, W; Hofstra, CL; Jiang, X; Li, X; Liu, C; Lovenberg, TW; Ma, X; Pyati, J; Wilson, SJ | 1 |
| Anthes, JC; Bayne, M; Behan, J; Gonsiorek, W; Greene, J; Greenfeder, SA; Gustafson, EL; Hedrick, JA; Hipkin, RW; Laz, TM; Monsma, FJ; Morse, KL; Qiao, X; Shin, N; Umland, S; Wan, Y; Wang, S; West, RE | 1 |
| Audinot, V; Beauverger, P; Boutin, JA; Cogé, F; Galizzi, JP; Guénin, SP; Macia, C; Nagel, N; Ouvry, C; Renouard-Try, A; Rique, H | 1 |
| Kuei, C; Liu, C; Lovenberg, TW; Wilson, SJ | 1 |
| Hastrup, S; Rimvall, K; Wulff, BS | 1 |
| Chen, J; Liu, C; Lovenberg, TW | 1 |
| Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM | 1 |
| Falus, A; Jelinek, I; Keseru, GM; Kiss, B; Kiss, R; Könczöl, A; László, V; Noszál, B; Szalai, F | 1 |
| Ito, S; Mitobe, Y; Mizutani, T; Nagase, T; Sato, N; Tokita, S | 1 |
| de Esch, IJ; de Graaf, C; Istyastono, EP; Kooistra, AJ; Leurs, R; Lim, HD; Nijmeijer, S; Roumen, L; van de Stolpe, A; Vischer, HF | 1 |
| Grätz, L; Humphrys, LJ; Işbilir, A; Lohse, MJ; Möller, J; Nagl, M; Pockes, S; Rosier, N; Schihada, H; Seibel, U | 1 |
| Buczko, W; Godlewski, G; Malinowska, B; Schlicker, E | 1 |
| Hemedah, M; Mitchelson, F | 1 |
| Bacciottini, L; Blandina, P; Cecchi, M; Giorgetti, M; Giovannini, MG | 1 |
| Aarden, LA; Alewijnse, AE; Boeije, LC; de Groot, ER; Leurs, R; Snijders, A; van der Pouw Kraan, TC | 1 |
| Schlicker, E; Werthwein, S; Zentner, J | 1 |
| de Wildt, DJ; Hendriksen, CF; van de Kuil, A; van den Hout, JW; Vleeming, W | 1 |
| Chen, Z; Fujii, Y; Ishizawa, K; Kamei, C; Okuma, C; Sugimoto, Y | 1 |
| Aceves, J; Arias-Montaño, JA; Floran, B; Garcia, M; Young, JM | 1 |
| Chen, Z | 1 |
| Barnes, W; Boyd, D; Hough, L | 1 |
| Blanco, I; Gomez-Ramirez, J; Ortiz, J | 1 |
| Chen, Z; Hu, WW; Huang, YW; Wei, EQ; Yanai, K; Zhang, LS | 1 |
| Buckland, KF; Conroy, DM; Williams, TJ | 1 |
| Fujii, Y; Hossen, MA; Kamei, C; Kayasuga, R; Sugimoto, Y | 1 |
| Chen, Z; Hu, WW; Jin, CL; Shen, HQ; Zhang, LS; Zhao, MH | 1 |
| Fu, YL; He, SH; Xie, H | 1 |
| Djahanguiri, B; Khalilzadeh, A; Zarrindast, MR | 1 |
| Blanks, AM; Lee, K; Renaud, LP; Spanswick, D; Whyment, AD | 1 |
| Eckman, JR; Wagner, MC; Wick, TM | 1 |
| Holopainen, IE; Kukko-Lukjanov, TK; Michelsen, KA; Panula, P; Soini, S; Taira, T | 1 |
| Carr, TL; Cassar, S; Esbenshade, TA; Faghih, R; Hancock, AA; Krueger, KM; Miller, TR; Sharma, R; Surber, BW; Witte, DG; Yao, BB | 1 |
| Blanco, I; de Esch, I; Gómez-Ramírez, J; Moreno-Delgado, D; Ortiz, J; Torrent, A | 1 |
| Arias-Montaño, JA; Garduño-Torres, B; Gutiérrez, R; Treviño, M | 1 |
| Chen, Z; Dai, HB; Fu, QL; Shen, Y | 1 |
| Chazot, P; Dijkstra, D; Gutzmer, R; Leurs, R; Shenton, FC; Stark, H; Werfel, T | 1 |
| Brzozowski, T; Gaca, P; Hahn, EG; Konturek, PC; Konturek, SJ; Pawlik, M; Raithel, M | 1 |
| Bergoc, R; Crescenti, E; Cricco, G; Croci, M; Martin, G; Massari, N; Medina, V; Mohamad, N; Nuñez, M; Rivera, E; Sanchez-Jiménez, F | 1 |
| Hatano, K; Ishizuka, T; Murotani, T; Yamatodani, A | 1 |
| Kamei, C; Kuyama, S; Ogawa, M; Yokota, E | 1 |
| Bäumer, W; Chazot, P; Dijkstra, D; Gutzmer, R; Kietzmann, M; Stark, H; Wendorff, S; Werfel, T | 1 |
| Barrett, P; Ebling, FJ; Enright, RA; Jethwa, PH; Murphy, M; Turnbull, Y; Warner, A | 1 |
| Khodarahmi, P; Oryan, S; Rezayof, A; Zarrindast, MR | 1 |
| Bäumer, W; Kietzmann, M; Leurs, R; Rossbach, K; Sander, K; Stark, H | 1 |
| Khanam, R; Manocha, A; Uma Devi, P; Vohora, D | 1 |
| Bertron, AF; Dy, M; Schneider, E | 1 |
| Bergoc, RM; Cricco, GP; Croci, M; Martinel Lamas, DJ; Massari, NA; Medina, VA; Rivera, ES; Sambuco, L | 1 |
| Akhtar, M; Goswami, D; Jahan, K; Mahmood, D | 1 |
| Bachelerie, F; Chauveau, L; Cutolo, P; Davidson, S; Durroux, T; Dutrieux, J; Dy, M; Herbeuval, JP; Manoury, B; McCort-Tranchepain, I; Münch, J; Nisole, S; Pietrancosta, N; Schwartz, O; Scott-Algara, D; Smith, N; Wack, A; Zirafi, O | 1 |
| An, S; Chen, LY; Guo, XX; Hao, Q; Liu, Y; Ma, L; Pediani, JD; Tang, M; Ward, RJ; Wu, N; Xu, TR; Yang, Y; Zeng, H | 1 |
| Bryukhovetskiy, I; Buzoianu, AD; Castellani, RJ; Lafuente, JV; Manzhulo, I; Menon, PK; Muresanu, DF; Nozari, A; Patnaik, R; Sahib, S; Sharma, A; Sharma, HS; Skaper, SD; Tian, ZR; Wiklund, L | 1 |
| Buzoianu, AD; Chen, L; Feng, L; Huang, H; Lafuente, JV; Muresanu, DF; Nozari, A; Sharma, A; Sharma, HS; Tian, ZR; Wiklund, L | 1 |
3 review(s) available for histamine and clobenpropit
| Article | Year |
|---|---|
Modulation of hematopoiesis through histamine receptor signaling.
Topics: Animals; Cell Cycle; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p21; Hematopoiesis; Hematopoietic Stem Cells; Histamine; Humans; Imidazoles; Mice; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Signal Transduction; Thiourea | 2011 |
Histamine H3 and H4 receptors modulate Parkinson's disease induced brain pathology. Neuroprotective effects of nanowired BF-2649 and clobenpropit with anti-histamine-antibody therapy.
Topics: Corpus Striatum; Histamine; Humans; Imidazoles; Neuroprotective Agents; Parkinson Disease; Receptors, Histamine H4; Thiourea | 2021 |
Nanodelivery of Histamine H3/H4 Receptor Modulators BF-2649 and Clobenpropit with Antibodies to Amyloid Beta Peptide in Combination with Alpha Synuclein Reduces Brain Pathology in Parkinson's Disease.
Topics: alpha-Synuclein; Amyloid beta-Peptides; Antibodies, Monoclonal; Brain; Drug Inverse Agonism; Histamine; Humans; Nanoparticle Drug Delivery System; Parkinson Disease; Receptors, Histamine H3; Receptors, Histamine H4 | 2023 |
53 other study(ies) available for histamine and clobenpropit
| Article | Year |
|---|---|
Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.
Topics: Animals; Autoradiography; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Histamine Agonists; Histamine Antagonists; Imidazoles; In Vitro Techniques; Ligands; Male; Propylamines; Rats; Rats, Wistar; Receptors, Histamine H3; Stereoisomerism; Structure-Activity Relationship | 1999 |
Cloning of rat histamine H(3) receptor reveals distinct species pharmacological profiles.
Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Animals; Cloning, Molecular; Dose-Response Relationship, Drug; Humans; Methylhistamines; Molecular Sequence Data; Rats; Receptors, Histamine H3; Recombinant Proteins; RNA, Messenger | 2000 |
Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Binding, Competitive; COS Cells; DNA, Complementary; Dose-Response Relationship, Drug; Histamine Antagonists; Humans; Imidazoles; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Piperidines; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, Histamine H3; Sequence Alignment; Sequence Homology, Amino Acid; Tritium | 2000 |
The rat H3 receptor: gene organization and multiple isoforms.
Topics: Animals; Autoradiography; Brain; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Frameshift Mutation; Genetic Variation; In Situ Hybridization; Introns; Iodine Radioisotopes; Organ Specificity; Protein Isoforms; Radioligand Assay; Rats; Receptors, Histamine H3; Recombinant Proteins; Sequence Deletion; Transcription, Genetic; Transfection | 2001 |
Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Bone Marrow; Cloning, Molecular; Histamine; Humans; Methylhistamines; Molecular Sequence Data; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; RNA, Messenger; Sequence Homology, Amino Acid; Tissue Distribution; Tritium | 2001 |
Cloning and characterization of a novel human histamine receptor.
Topics: Amino Acid Sequence; Cells, Cultured; Cloning, Molecular; Histamine; Histamine Agonists; Humans; Imidazoles; Molecular Sequence Data; Radioligand Assay; Receptors, Histamine; Receptors, Histamine H3; RNA, Messenger; Sequence Homology, Amino Acid; Thiourea; Tissue Distribution; Transfection | 2001 |
Genomic organization and characterization of splice variants of the human histamine H3 receptor.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Calcium; CHO Cells; Cloning, Molecular; Cricetinae; DNA, Complementary; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Microscopy, Fluorescence; Molecular Sequence Data; Protein Binding; Receptors, Histamine H3; Sequence Homology, Amino Acid; Sulfur Radioisotopes | 2001 |
Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation.
Topics: Amino Acid Sequence; Animals; Calcium; Cell Line; Cloning, Molecular; COS Cells; Cyclic AMP; DNA Fragmentation; Guinea Pigs; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity; Transfection | 2001 |
Characteristics of recombinantly expressed rat and human histamine H3 receptors.
Topics: Animals; Cell Line; Cloning, Molecular; Histamine Agonists; Histamine Antagonists; Humans; Rats; Receptors, Histamine; Receptors, Histamine H3; Recombination, Genetic | 2002 |
Molecular and pharmacological characterization of the mouse histamine H3 receptor.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Brain; Calcium; Cells, Cultured; Chlorocebus aethiops; Cloning, Molecular; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Mice; Molecular Sequence Data; Rats; Receptors, Histamine H3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology; Thiourea | 2003 |
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4 | 2005 |
Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening.
Topics: Binding, Competitive; Cell Line, Tumor; Databases, Factual; Histamine Antagonists; Humans; Ligands; Models, Molecular; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship | 2008 |
Development of a selective and potent radioactive ligand for histamine H(3) receptors: A compound potentially useful for receptor occupancy studies.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Brain; Chemistry, Pharmaceutical; Drug Design; Humans; Kinetics; Ligands; Mice; Models, Chemical; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Histamine H3; Structure-Activity Relationship | 2009 |
Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies.
Topics: Cell Line, Tumor; Histamine Antagonists; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Quantitative Structure-Activity Relationship; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Stereoisomerism; Thiourea | 2011 |
A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H
Topics: Binding Sites; Bioluminescence Resonance Energy Transfer Techniques; Dose-Response Relationship, Drug; Fluorescent Dyes; HEK293 Cells; Histamine H3 Antagonists; Humans; Ligands; Molecular Structure; Receptors, Histamine H3; Single Molecule Imaging; Structure-Activity Relationship | 2021 |
Inhibitory H3 receptors on sympathetic nerves of the pithed rat: activation by endogenous histamine and operation in spontaneously hypertensive rats.
Topics: Adrenergic Fibers; Animals; Blood Pressure; Decerebrate State; Electric Stimulation; Histamine; Histamine Agonists; Histamine Antagonists; Hypertension; Imidazoles; Male; Methylhistamines; Piperidines; Pyrimethamine; Rats; Rats, Wistar; Receptors, Histamine H3; Thiourea; Vagotomy; Vascular Resistance | 1997 |
Comparison of the effects of histamine and N(alpha)-methylhistamine on neuronal function in the guinea-pig oesophagus and ileum.
Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Esophagus; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; Imidazoles; In Vitro Techniques; Methylhistamines; Muscle, Skeletal; Muscle, Smooth; Neurons; Neurons, Afferent; Pyrilamine; Receptors, Cholinergic; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Tetrodotoxin; Thiourea; Vagus Nerve | 1997 |
Increase of acetylcholine release from cortex of freely moving rats by administration of histamine into the nucleus basalis magnocellularis.
Topics: Acetylcholine; Animals; Cerebral Cortex; Cimetidine; Electroencephalography; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Imidazoles; Male; Neurons; Rats; Rats, Wistar; Substantia Innominata; Telencephalon; Thiourea; Triprolidine | 1998 |
Histamine inhibits the production of interleukin-12 through interaction with H2 receptors.
Topics: Dinoprostone; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Interleukin-12; Interleukins; Monocytes; Ranitidine; Receptors, Histamine H2; RNA, Messenger; Thiourea; Triprolidine | 1998 |
Histamine H3 receptor-mediated inhibition of noradrenaline release in the human brain.
Topics: Animals; Brain; Cerebral Cortex; Dimethindene; Electric Stimulation; Hippocampus; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Male; Mice; Mice, Inbred Strains; Norepinephrine; Piperidines; Ranitidine; Receptors, Histamine H3; Thiourea; Tritium | 1999 |
Mepyramine but not cimetidine or clobenpropit blocks pertussis toxin-induced histamine sensitization in rats.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Cimetidine; Drug Interactions; Histamine; Histamine Antagonists; Imidazoles; Male; Pertussis Toxin; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine; Thiourea; Virulence Factors, Bordetella | 2000 |
Participation of GABAergic and histaminergic systems in inhibiting amygdaloid kindled seizures.
Topics: Amygdala; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Histamine; Imidazoles; Kindling, Neurologic; Male; Muscimol; Rats; Rats, Wistar; Seizures; Thiourea; Valproic Acid | 2000 |
Histamine H(3) receptor-mediated inhibition of depolarization-induced, dopamine D(1) receptor-dependent release of [(3)H]-gamma-aminobutryic acid from rat striatal slices.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Calcium; Dopamine; Dopamine D2 Receptor Antagonists; gamma-Aminobutyric Acid; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; In Vitro Techniques; Male; Membrane Potentials; Neostriatum; Piperidines; Potassium; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Histamine H3; Reserpine; Sulpiride; Thiourea | 2001 |
Effect of histamine H3-receptor antagonist clobenpropit on spatial memory of radial maze performance in rats.
Topics: Animals; Brain; Histamine; Histamine Antagonists; Imidazoles; Injections, Intraventricular; Male; Maze Learning; Memory Disorders; Rats; Rats, Wistar; Scopolamine; Thiourea | 2000 |
Dynamics of histamine H(3) receptor antagonists on brain histamine metabolism: do all histamine H(3) receptor antagonists act at a single site?
Topics: Analysis of Variance; Animals; Binding Sites; Brain; Histamine; Histamine Antagonists; Imidazoles; Male; Methylhistamines; Mice; Pargyline; Piperidines; Rats; Receptors, Histamine H3; Thiourea | 2001 |
Presynaptic H3 autoreceptors modulate histamine synthesis through cAMP pathway.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Bucladesine; Colforsin; Cyclic AMP; Drug Interactions; Histamine; Imidazoles; In Vitro Techniques; Male; Piperidines; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Thionucleotides; Thiourea | 2002 |
Effects of endogenous histamine on seizure development of pentylenetetrazole-induced kindling in rats.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Histamine; Histamine Release; Histidine; Imidazoles; Injections, Intraventricular; Kindling, Neurologic; Male; Methylhistidines; Pentylenetetrazole; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Seizures; Thiourea | 2003 |
Histamine induces cytoskeletal changes in human eosinophils via the H(4) receptor.
Topics: Actins; Calcium; CD11b Antigen; Cell Size; Chemokine CCL11; Chemokines, CC; Chemotaxis; Clozapine; Cytoskeleton; Dose-Response Relationship, Drug; Eosinophils; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Pertussis Toxin; Piperidines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Thiourea; Up-Regulation | 2003 |
Histamine H3 receptors regulate vascular permeability changes in the skin of mast cell-deficient mice.
Topics: Animals; Capillary Permeability; Chlorpheniramine; Diphenhydramine; Evans Blue; Female; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Injections, Intradermal; Injections, Intravenous; Isothiuronium; Mast Cells; Mice; Mice, Mutant Strains; Piperidines; Receptors, Histamine H3; Skin; Thiourea; Tryptophan | 2003 |
[Mechanisms of the effect of brain histamine on chronic epilepsy induced by pentylenetetrazole].
Topics: Animals; Brain; Chronic Disease; Dose-Response Relationship, Drug; Epilepsy; Histamine; Histidine; Imidazoles; Male; Pentylenetetrazole; Piperidines; Rats; Rats, Sprague-Dawley; Thiourea | 2004 |
Inhibition of tryptase release from human colon mast cells by histamine receptor antagonists.
Topics: Calcimycin; Cells, Cultured; Cimetidine; Colon; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Ionophores; Mast Cells; Serine Endopeptidases; Serine Proteinase Inhibitors; Terfenadine; Thiourea; Tryptases | 2005 |
Effects of intracerebroventricular administration of ultra low doses of histaminergic drugs on morphine state-dependent memory of passive avoidance in mice.
Topics: Analgesics, Opioid; Animals; Avoidance Learning; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histamine Agents; Imidazoles; Injections, Intraventricular; Male; Memory; Mice; Morphine; Morphine Dependence; Pyrilamine; Reaction Time; Thiourea | 2006 |
Histamine excites neonatal rat sympathetic preganglionic neurons in vitro via activation of H1 receptors.
Topics: Action Potentials; Animals; Animals, Newborn; Autonomic Fibers, Preganglionic; Barium; Dimaprit; Female; Ganglia, Sympathetic; Histamine; Histamine Agonists; Histamine H1 Antagonists; Imidazoles; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium; Rats; Rats, Inbred WKY; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiourea; Triprolidine | 2006 |
Histamine increases sickle erythrocyte adherence to endothelium.
Topics: Analysis of Variance; Anemia, Sickle Cell; Cell Adhesion; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Erythrocytes; Famotidine; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Methylhistamines; P-Selectin; Piperidines; Pyrilamine; Stimulation, Chemical; Thiazoles; Thiourea; Venules | 2006 |
Histaminergic neurons protect the developing hippocampus from kainic acid-induced neuronal damage in an organotypic coculture system.
Topics: Animals; Cell Death; Cells, Cultured; Coculture Techniques; Convulsants; Hippocampus; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Hypothalamus, Anterior; Hypothalamus, Posterior; Imidazoles; Kainic Acid; Methylhistidines; Microscopy, Confocal; Neurons; Neuroprotective Agents; Organ Culture Techniques; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Receptors, Histamine H3; Thiourea; Triprolidine | 2006 |
Detection of multiple H3 receptor affinity states utilizing [3H]A-349821, a novel, selective, non-imidazole histamine H3 receptor inverse agonist radioligand.
Topics: Animals; Binding, Competitive; Biphenyl Compounds; Cells, Cultured; Guanosine Diphosphate; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Methylhistamines; Models, Biological; Protein Binding; Radioligand Assay; Rats; Receptors, Histamine H3; Thiourea | 2006 |
Constitutive activity of H3 autoreceptors modulates histamine synthesis in rat brain through the cAMP/PKA pathway.
Topics: Animals; Biphenyl Compounds; Brain; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; In Vitro Techniques; Male; Models, Biological; Nitriles; Piperidines; Potassium; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Thiourea | 2006 |
Pre-synaptic histamine H3 receptors regulate glutamate, but not GABA release in rat thalamus.
Topics: 4-Aminopyridine; Animals; Dose-Response Relationship, Drug; Drug Interactions; Evoked Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Histamine; Histamine Antagonists; Imidazoles; In Vitro Techniques; Male; Methylhistamines; Pertussis Toxin; Presynaptic Terminals; Protein Binding; Rats; Rats, Wistar; Receptors, Histamine H3; Synaptosomes; Thalamus; Thiourea; Tritium | 2007 |
[Reversing effect of histamine on neurotoxicity induced by beta-amyloid1-42].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Histamine H2 Antagonists; Histamine H3 Antagonists; Imidazoles; Neuroprotective Agents; PC12 Cells; Phenoxypropanolamines; Piperidines; Rats; Receptors, Histamine H2; Receptors, Histamine H3; Thiourea | 2007 |
Histamine downregulates monocyte CCL2 production through the histamine H4 receptor.
Topics: Calcium; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Down-Regulation; Histamine; Histamine Agonists; Humans; Imidazoles; Indoles; Interferon-gamma; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Matrix Metalloproteinase 8; Methylhistamines; Monocytes; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Thiourea; Up-Regulation | 2007 |
Role of histamine in ghrelin-induced gastroprotection against acute gastric lesions.
Topics: Animals; Anti-Ulcer Agents; Cytoprotection; Ethanol; Gastric Mucosa; Ghrelin; Histamine; Histamine Antagonists; Imidazoles; Male; Peptide Hormones; Ranitidine; Rats; Rats, Wistar; Regional Blood Flow; Thiourea | 2007 |
The role of histamine in human mammary carcinogenesis: H3 and H4 receptors as potential therapeutic targets for breast cancer treatment.
Topics: Adult; Aged; Breast; Breast Neoplasms; Cell Movement; Cell Proliferation; Female; Histamine; Histidine Decarboxylase; Humans; Imidazoles; Middle Aged; Proliferating Cell Nuclear Antigen; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Thiourea | 2008 |
Comparison of the effect of an H(3)-inverse agonist on energy intake and hypothalamic histamine release in normal mice and leptin resistant mice with high fat diet-induced obesity.
Topics: Analysis of Variance; Animals; Behavior, Animal; Body Weight; Chromatography, High Pressure Liquid; Electrochemistry; Energy Intake; Fats; Histamine; Histamine H3 Antagonists; Hypothalamus; Imidazoles; Leptin; Male; Mice; Mice, Inbred C57BL; Microdialysis; Obesity; Thiourea; Time Factors | 2008 |
Substance P is involved in the effect of histamine H3 receptor agonist, Sch 50971 on nasal allergic symptoms in mice.
Topics: Animals; Capsaicin; Cetirizine; Disease Models, Animal; Female; Histamine; Histamine Agonists; Histamine H1 Antagonists, Non-Sedating; Imidazoles; Mice; Mice, Inbred BALB C; Ovalbumin; Piperidines; Pyrrolidines; Receptors, Histamine H3; Rhinitis, Allergic, Perennial; Substance P; Thiourea | 2008 |
Histamine H4 receptors modulate dendritic cell migration through skin--immunomodulatory role of histamine.
Topics: Animals; Cell Movement; Chemotaxis, Leukocyte; Dendritic Cells; Female; Guinea Pigs; Histamine; Histamine H3 Antagonists; Imidazoles; Immunologic Factors; Injections, Intradermal; Mice; Mice, Inbred BALB C; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Skin; Thiourea | 2008 |
The role of histamine 3 receptors in the control of food intake in a seasonal model of obesity: the Siberian hamster.
Topics: Animals; Body Temperature; Cell Line, Transformed; Cricetinae; Disease Models, Animal; Eating; Histamine; Imidazoles; Injections, Intraventricular; Motor Activity; Obesity; Phodopus; Photoperiod; Piperidines; Receptors, Histamine H3; Seasons; Thiourea; Transfection | 2009 |
Withdrawal from repeated administration of morphine alters histamine-induced anxiogenic effects produced by intra-ventral hippocampal microinjection.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Hippocampus; Histamine; Histamine Antagonists; Imidazoles; Male; Microinjections; Morphine; Motor Activity; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Thiourea | 2010 |
The histamine H receptor as a new target for treatment of canine inflammatory skin diseases.
Topics: Animals; Calcium; Cell Line; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Female; Guanidines; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Indoles; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Mastocytoma; Mice; Mice, Inbred BALB C; Peptides; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Skin Diseases; Thiourea; Wasp Venoms | 2009 |
Beneficial interaction between clobenpropit and pyridoxine in prevention of electroshock-induced seizures in mice: lack of histaminergic mechanisms.
Topics: Animals; Anticonvulsants; Brain; Drug Interactions; Electroshock; Female; Histamine; Histamine H3 Antagonists; Histidine Decarboxylase; Imidazoles; Male; Mice; Pyridoxine; Seizures; Thiourea | 2011 |
Role of H4 receptor in histamine-mediated responses in human melanoma.
Topics: Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Guanidines; Histamine; Humans; Imidazoles; Immunohistochemistry; Indoles; Melanoma; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; RNA, Messenger; Skin Neoplasms; Thiourea | 2011 |
Histamine H3 receptor antagonists display antischizophrenic activities in rats treated with MK-801.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Histamine; Histamine H3 Antagonists; Imidazoles; Methylhistamines; Motor Activity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Thiourea | 2016 |
Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement.
Topics: Amines; Ammonium Compounds; Animals; Dendritic Cells; Histamine; HIV; Humans; Imidazoles; Interferon Type I; Mice; Orthomyxoviridae; Receptors, CXCR4; Receptors, Histamine; Thiourea; TNF-Related Apoptosis-Inducing Ligand | 2017 |
Visualization of the activation of the histamine H3 receptor (H3R) using novel fluorescence resonance energy transfer biosensors and their potential application to the study of H3R pharmacology.
Topics: Bacterial Proteins; Biosensing Techniques; Cyclic AMP; Fluorescence Resonance Energy Transfer; Gene Expression; Green Fluorescent Proteins; HEK293 Cells; Histamine; Histamine Agonists; Histamine H3 Antagonists; Humans; Imidazoles; Kinetics; Luminescent Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Plasmids; Receptors, Histamine H3; Thiourea; Transfection; Tritium | 2018 |