histamine has been researched along with azelastine in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (24.44) | 18.7374 |
| 1990's | 22 (48.89) | 18.2507 |
| 2000's | 6 (13.33) | 29.6817 |
| 2010's | 6 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Baroody, F; Kagey-Sobotka, A; Lichtenstein, LM; Naclerio, RM; Proud, D; Shin, MH | 1 |
| Go, K; Namimatsu, A; Okuda, M; Tanimoto, H | 1 |
| Davies, RJ; Ferguson, H; Ollier, S; Thomas, KE | 1 |
| Lefort, J; Perrisoud, D; Pretolani, M; Vargaftig, BB; Venco, C | 1 |
| Chiyotani, A; Isono, K; Kanemura, T; Sakai, N; Takeuchi, S; Takeyama, K; Takizawa, T; Tamaoki, J | 1 |
| Holgate, ST; Lai, CK; Lau, CK; Ollier, S | 1 |
| Cordeiro, RS; Lima, MC; Martins, MA; Perez, SA; Silva, PM; Vargaftig, BB | 1 |
| Herold, H; Stroman, F; Szelenyi, I | 1 |
| Nakagawa, T | 1 |
| Kanai, Y; Misawa, M | 1 |
| Kurosawa, M | 1 |
| Rafferty, P | 1 |
| Aurich, R; Bauer, K; Kaik, G | 1 |
| Hoshino, K; Kawasaki, A; Mizushima, Y; Yano, S | 1 |
| Aurich, R; Jörres, R; Magnussen, H; Reuss, G | 1 |
| Horie, T; Kikuchi, H; Ohkuma, A; Ohtsuka, A; Okayasu, M; Yoshizawa, T | 1 |
| Lee, HK; Sperelakis, N | 1 |
| Aurich, R; Church, MK; Clough, J; Holgate, ST; Ng, WH; Ollier, S; Phillips, G; Rafferty, P | 1 |
| Holgate, ST; Rafferty, P | 1 |
| Magnussen, H | 1 |
| Albazzaz, MK; Patel, KR | 1 |
| Achterrath-Tuckermann, U; Szelenyi, I | 1 |
| Aurich, R; Harrison, PJ; Holgate, ST; Rafferty, P | 1 |
| Aizawa, H; Ejima, T; Miyazaki, N; Shigematsu, N; Tomooka, M | 1 |
| Hamada, M; Hasegawa, M; Ida, M; Matsui, C; Morohashi, M | 1 |
| Kamikawa, Y | 1 |
| Holgate, ST; Ollier, S; Twentyman, OP | 1 |
| Berkebile, C; Friedman, BS; Metcalfe, DD; Santiago, ML | 1 |
| Horio, T; Miyauchi, H | 1 |
| Ashida, Y; Fukuda, S; Matsumoto, T; Nagaya, H; Nakayama, T; Yamasaki, M | 1 |
| Andersson, M; Greiff, L; Persson, CG; Svensson, C | 1 |
| Asai, S; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Takao, A | 1 |
| Jacobi, HH; Malling, HJ; Mygind, N; Poulsen, LK; Skov, PS | 1 |
| Andoh, T; Kuraishi, Y | 1 |
| Grossman, J; Meltzer, EO; Pearlman, DS | 1 |
| Kim, DH; Shin, YW | 1 |
| Beauregard, C; Gamache, D; Roberts, L; Stephens, D; Yanni, J | 1 |
| Agarwal, MK; Vermani, M; Vijayan, VK | 1 |
| Bonini, S; Lambiase, A; Micera, A | 1 |
| Andoh, T; Hattori, M; Kuraishi, Y; Tanaka, K; Tayama, M; Yamamoto, T; Zhang, Q | 1 |
| Asano, K; Furuta, A; Hirano, K; Shoji, N; Suzaki, H | 1 |
| Han, MJ; Jang, SE; Joh, EH; Jung, IH; Kim, DH | 1 |
| Bäumer, W; Kietzmann, M; Schumacher, S; Stark, H | 1 |
| Chen, SG; Chu, YH; Lee, FP; Lin, CS; Liu, SC; Lu, HH; Wang, HW | 1 |
2 review(s) available for histamine and azelastine
| Article | Year |
|---|---|
Antihistamines in the treatment of clinical asthma.
Topics: Animals; Asthma; Benzhydryl Compounds; Cetirizine; Dose-Response Relationship, Drug; Forced Expiratory Volume; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Delayed; Peak Expiratory Flow Rate; Phthalazines; Terfenadine | 1990 |
Multiple action agents and the eye: do they really stabilize mast cells?
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Conjunctivitis, Allergic; Cytokines; Dibenzazepines; Dibenzoxepins; Histamine; Histamine Antagonists; Humans; Imidazoles; Immunity, Innate; Ketotifen; Mast Cells; Olopatadine Hydrochloride; Phthalazines | 2009 |
17 trial(s) available for histamine and azelastine
| Article | Year |
|---|---|
The effect of azelastine on the early allergic response.
Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Kinins; Male; Nasal Cavity; Nasal Provocation Tests; Peptide Hydrolases; Phthalazines; Prostaglandin D2; Sneezing; Therapeutic Irrigation | 1992 |
The effect of intranasal azelastine, Rhinolast, on nasal airways obstruction and sneezing following provocation testing with histamine and allergen.
Topics: Administration, Intranasal; Adult; Allergens; Bronchodilator Agents; Female; Hemodynamics; Histamine; Humans; Male; Middle Aged; Nasal Obstruction; Nasal Provocation Tests; Phthalazines; Rhinitis, Allergic, Seasonal; Sneezing | 1992 |
Effect of azelastine and ketotifen on the bronchial and skin responses to platelet-activating factor in humans.
Topics: Adult; Bronchoconstriction; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Ketotifen; Male; Middle Aged; Phthalazines; Platelet Activating Factor; Skin | 1991 |
Dose related protective effect of azelastine on histamine induced bronchoconstriction in extrinsic asthma.
Topics: Airway Resistance; Blood Pressure; Bronchi; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Histamine; Histamine H1 Antagonists; Humans; Phthalazines | 1990 |
Duration of the effect of a single dose of azelastine on histamine-induced bronchoconstriction.
Topics: Administration, Oral; Adult; Airway Resistance; Bronchial Provocation Tests; Bronchial Spasm; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Phthalazines; Pyridazines; Random Allocation | 1989 |
The inhibitory actions of azelastine hydrochloride on the early and late bronchoconstrictor responses to inhaled allergen in atopic asthma.
Topics: Adult; Allergens; Asthma; Bronchi; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Phthalazines; Pyridazines; Time Factors | 1989 |
The inhibitory effect of azelastine hydrochloride on histamine- and allergen-induced bronchoconstriction in atopic asthma.
Topics: Administration, Inhalation; Administration, Oral; Adult; Asthma; Bronchi; Double-Blind Method; Forced Expiratory Volume; Histamine; Humans; Phthalazines; Pollen; Pyridazines; Random Allocation; Time Factors | 1989 |
The inhibitory effect of azelastine and ketotifen on histamine-induced bronchoconstriction in asthmatic patients.
Topics: Adult; Asthma; Bronchial Provocation Tests; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Ketotifen; Male; Phthalazines; Pyridazines; Random Allocation | 1987 |
Effect of azelastine on bronchoconstriction induced by histamine and leukotriene C4 in patients with extrinsic asthma.
Topics: Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Male; Phthalazines; Pyridazines; SRS-A | 1988 |
The in vivo potency and selectivity of azelastine as an H1 histamine-receptor antagonist in human airways and skin.
Topics: Administration, Inhalation; Adult; Bronchial Spasm; Dose-Response Relationship, Immunologic; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Methacholine Chloride; Methacholine Compounds; Middle Aged; Phthalazines; Pyridazines; Skin Tests | 1988 |
Effects of azelastin on pruritus and plasma histamine levels in hemodialysis patients.
Topics: Adult; Aged; Erythropoietin; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Phthalazines; Pruritus; Renal Dialysis | 1994 |
The effect of H1-receptor blockade on the development of early- and late-phase bronchoconstriction and increased bronchial responsiveness in allergen-induced asthma.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Male; Methacholine Chloride; Phthalazines; Prostaglandin D2 | 1993 |
Comparison of azelastine and chlorpheniramine in the treatment of mastocytosis.
Topics: Adult; Aged; Chlorpheniramine; Double-Blind Method; Drug Administration Schedule; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Mastocytosis; Middle Aged; Phthalazines; Skin Tests; Urticaria | 1993 |
Topical azelastine has a 12-hour duration of action as assessed by histamine challenge-induced exudation of alpha 2-macroglobulin into human nasal airways.
Topics: Administration, Intranasal; Administration, Oral; Adult; alpha-Macroglobulins; Cetirizine; Cross-Over Studies; Double-Blind Method; Exudates and Transudates; Histamine; Histamine H1 Antagonists; Humans; Nasal Mucosa; Nasal Provocation Tests; Phthalazines; Therapeutic Irrigation; Time Factors | 1997 |
Histamine and tryptase in nasal lavage fluid after allergen challenge: effect of 1 week of pretreatment with intranasal azelastine or systemic cetirizine.
Topics: Administration, Intranasal; Adult; Cetirizine; Chymases; Double-Blind Method; Female; Histamine; Humans; Inflammation Mediators; Male; Mast Cells; Nasal Lavage Fluid; Nasal Provocation Tests; Phthalazines; Premedication; Serine Endopeptidases; Time Factors; Tryptases | 1999 |
Histamine skin test reactivity following single and multiple doses of azelastine nasal spray in patients with seasonal allergic rhinitis.
Topics: Administration, Intranasal; Adolescent; Adult; Anti-Allergic Agents; Child; Double-Blind Method; Female; Histamine; Humans; Male; Middle Aged; Phthalazines; Rhinitis, Allergic, Seasonal; Skin Tests; Southwestern United States; Time Factors | 2003 |
Effect of azelastine nasal spray on histamine-and allergen-induced skin wheal response in patients with allergic rhinitis.
Topics: Administration, Intranasal; Adolescent; Adult; Anti-Allergic Agents; Child; Female; Histamine; Humans; Male; Middle Aged; Phthalazines; Rhinitis, Allergic, Seasonal; Skin Tests; Time Factors | 2008 |
26 other study(ies) available for histamine and azelastine
| Article | Year |
|---|---|
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Mechanism of nasal secretion mediated via nerve reflex in guinea pigs and evaluation of antiallergic drugs.
Topics: Allergens; Aminopyridines; Animals; Atropine Derivatives; Bronchodilator Agents; Capsaicin; Ganglionic Blockers; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Histamine; Hypersensitivity; Lidocaine; Methacholine Chloride; Nasal Mucosa; ortho-Aminobenzoates; Parasympatholytics; Phthalazines; Pyrilamine; Reflex | 1992 |
Inhibition by azelastine of the effects of platelet-activating factor in lungs from actively sensitised guinea-pigs.
Topics: Animals; Arachidonic Acid; Bronchoconstriction; Guinea Pigs; Histamine; Immunization; Injections, Intra-Arterial; Leukotrienes; Lung; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pulmonary Artery; Thromboxane B2 | 1992 |
[Effect of histamine on electrical properties of airway epithelium and its antagonism by azelastine].
Topics: Animals; Cells, Cultured; Chlorine; Dogs; Dose-Response Relationship, Drug; Epithelial Cells; Histamine; Histamine H1 Antagonists; Membrane Potentials; Phthalazines; Prostaglandins; Trachea | 1991 |
Effect of azelastine on platelet-activating factor and antigen-induced pleurisy in rats.
Topics: Animals; Antigens; Female; Histamine; Histamine H1 Antagonists; Leukocytes; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Pleural Effusion; Pleurisy; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Protective property of azelastine against histamine challenge of rhinal mucosa in domestic pigs.
Topics: Animals; Female; Hemodynamics; Histamine; Histamine H1 Antagonists; Male; Nasal Mucosa; Phthalazines; Swine | 1991 |
[Chemical mediators and anti-mediator drugs].
Topics: Asthma; Chemotactic Factors, Eosinophil; Cromolyn Sodium; Cytokines; Depression, Chemical; Histamine; Humans; Hypersensitivity; Ketotifen; Mast Cells; ortho-Aminobenzoates; Phthalazines; SRS-A | 1991 |
Effect of the new antiallergic drug epinastine on chemical mediator induced bronchoconstrictions in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bradykinin; Bronchoconstriction; Dibenzazepines; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Neurokinin A; Phthalazines; Piperazines; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; SRS-A; Substance P | 1991 |
Inhibitory effects of azelastine on protein kinase C and diphosphoinositide kinase in rat mast cells.
Topics: Adenine; Animals; Cytoplasmic Granules; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Leukocytes; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Phosphorus Radioisotopes; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Phthalazines; Protein Kinase C; Pyridazines; Rats; Rats, Inbred Strains; Theophylline | 1990 |
[Improvement of airway hyperreactivity in bronchial asthma patients with short disease duration treated with anti-allergic agents].
Topics: Adult; Asthma; Bronchi; Cromolyn Sodium; Drug Therapy, Combination; Female; Histamine; Humans; Ketotifen; Male; Middle Aged; ortho-Aminobenzoates; Phthalazines; Time Factors | 1989 |
[Role of plasma histamine and neutrophil chemotactic factor in exercise-induced asthma].
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Chemotactic Factors; Female; Histamine; Histamine H1 Antagonists; Humans; Interleukin-8; Male; Middle Aged; Phthalazines | 1989 |
Azelastine inhibits agonist-induced electromechanical activity in canine tracheal muscle.
Topics: Acetylcholine; Animals; Asthma; Bronchodilator Agents; Dogs; Histamine; Histamine H1 Antagonists; Isometric Contraction; Membrane Potentials; Muscle, Smooth; Phthalazines; Pyridazines; Tetraethylammonium Compounds; Trachea | 1989 |
Azelastine inhibits bronchial hyperreactivity to acetylcholine in guinea pigs.
Topics: Acetylcholine; Animals; Antigens; Asthma; Bronchi; Guinea Pigs; Histamine; Histamine H1 Antagonists; Muscle Contraction; Ovalbumin; Phthalazines; Pyridazines; Trachea | 1988 |
[Azelastine inhibits bronchoconstriction induced by histamine and leukotriene C4].
Topics: Airway Resistance; Animals; Bronchi; Constriction, Pathologic; Guinea Pigs; Histamine; Histamine H1 Antagonists; Phthalazines; Platelet Activating Factor; Pyridazines; SRS-A | 1988 |
Influence of epithelial removal on the antihistaminic activity of azelastine in the guinea-pig airway smooth muscles.
Topics: Animals; Bronchi; Carbachol; Epithelium; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Phthalazines; Trachea | 1993 |
Detection of action, inhibition and augmentation spectra in solar urticaria.
Topics: Anaphylaxis; Anti-Allergic Agents; Betamethasone; Cyclizine; Erythema; Female; Glucocorticoids; Histamine; Histamine H1 Antagonists; Humans; Light; Middle Aged; Molecular Weight; Photosensitizing Agents; Phthalazines; Radiation Dosage; Skin; Spectrophotometry; Spectrophotometry, Ultraviolet; Sunlight; Terfenadine; Ultrafiltration; Ultraviolet Rays; Urticaria | 1995 |
Involvement of thromboxane A2 and histamine in experimental allergic rhinitis of guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antigens; Benzoquinones; Capillary Permeability; Guinea Pigs; Heptanoic Acids; Histamine; Histamine H1 Antagonists; Male; Nasal Mucosa; Phthalazines; Prostaglandin Antagonists; Prostaglandin Endoperoxides, Synthetic; Rhinitis, Allergic, Seasonal; Thromboxane A2 | 1997 |
Inhibitory effects of azelastine hydrochloride in alcohol-induced asthma.
Topics: Acetaldehyde; Adult; Aged; Asthma; Bronchoconstrictor Agents; Bronchodilator Agents; Ethanol; Female; Histamine; Humans; Leukotriene C4; Male; Middle Aged; Phthalazines; Respiratory Function Tests; Thromboxane B2 | 1999 |
Inhibitory effects of azelastine on substance P-induced itch-associated response in mice.
Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Calcium; Dinoprostone; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Leukotriene B4; Male; Mice; Mice, Inbred ICR; Neutrophils; Phthalazines; Pruritus; Skin; Substance P | 2002 |
Antipruritic effect of ginsenoside rb1 and compound k in scratching behavior mouse models.
Topics: Animals; Antipruritics; Behavior, Animal; Capillary Permeability; Disease Models, Animal; Ginsenosides; Histamine; Inhibitory Concentration 50; Male; Mice; p-Methoxy-N-methylphenethylamine; Phthalazines; Pruritus; Substance P; Time Factors | 2005 |
Duration of action of topical antiallergy drugs in a Guinea pig model of histamine-induced conjunctival vascular permeability.
Topics: Administration, Topical; Animals; Anti-Allergic Agents; Capillary Permeability; Conjunctiva; Delayed-Action Preparations; Dibenzazepines; Dibenzoxepins; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Olopatadine Hydrochloride; Ophthalmic Solutions; Phthalazines | 2007 |
Inhibitory effects of the methanol extract of Ganoderma lucidum on mosquito allergy-induced itch-associated responses in mice.
Topics: Animals; Antipruritics; Culicidae; Drugs, Chinese Herbal; Fruit; Histamine; Histamine H1 Antagonists, Non-Sedating; Histamine Release; Hypersensitivity; Injections, Intradermal; Male; Mast Cells; Methanol; Mice; Mice, Inbred ICR; Phthalazines; Phytotherapy; Pruritus; Receptors, Histamine; Reishi; Skin; Terfenadine | 2010 |
Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro.
Topics: Adult; Antigens, Plant; Cell Proliferation; Chemokine CCL17; Chemokine CCL22; Chlorpheniramine; Extracellular Signal-Regulated MAP Kinases; GATA1 Transcription Factor; Gene Expression; Histamine; Histamine H1 Antagonists; Humans; Ketotifen; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Macrophages; Male; Middle Aged; NF-kappa B; Phosphorylation; Phthalazines; Piperazines; Plant Proteins; Rhinitis, Allergic, Seasonal; Signal Transduction; Terfenadine; Tuberculin; Young Adult | 2011 |
Antibiotics attenuate anti-scratching behavioral effect of ginsenoside Re in mice.
Topics: Adult; Aged; Animals; Anti-Allergic Agents; Anti-Bacterial Agents; Bacteria, Anaerobic; Behavior, Animal; beta-Glucosidase; Enterobacteriaceae; Feces; Female; Ginsenosides; Glycoside Hydrolases; Histamine; Humans; Interleukin-4; Male; Mice; Mice, Inbred ICR; Middle Aged; Phthalazines; Pruritus; Tumor Necrosis Factor-alpha; Young Adult | 2012 |
Unique immunomodulatory effects of azelastine on dendritic cells in vitro.
Topics: Animals; Anti-Allergic Agents; Cell Proliferation; Dendritic Cells; Dermatitis, Allergic Contact; Disease Models, Animal; Female; Histamine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; In Vitro Techniques; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Phthalazines; T-Lymphocytes; Th2 Cells | 2014 |
Effect of budesonide and azelastine on histamine signaling regulation in human nasal epithelial cells.
Topics: Biomarkers; Blotting, Western; Budesonide; Cells, Cultured; Epithelial Cells; Glucocorticoids; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Immunohistochemistry; Nasal Mucosa; Phthalazines; Signal Transduction; Up-Regulation | 2017 |