histamine and alpha-methylhistamine

histamine has been researched along with alpha-methylhistamine in 105 studies

Research

Studies (105)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	55 (52.38)	18.2507
2000's	41 (39.05)	29.6817
2010's	7 (6.67)	24.3611
2020's	2 (1.90)	2.80

Authors

Authors	Studies
Chapman, RW; del Prado, M; Egan, RW; Hey, JA; Kreutner, W	1
Burgaud, JL; Javellaud, J; Oudart, N	1
Kilpatrick, GJ; Michel, AD; Taylor, SJ	1
Bull, HA; Courtney, PF; Dowd, PM; Rustin, MH	1
Bado, A; Laigneau, JP; Lewin, MJ; Moizo, L	1
Katsoulis, S; Racké, K; Schwörer, H	1
Maeyama, K; Sakai, N; Sakurai, A; Sakurai, E; Watanabe, T; Yanai, K	1
Anjelkovic, IZ; Collis, CS; Djuric, D; Rosic, M; Segal, MB; Zlokovic, BV	1
Bertaccini, G; Poli, E; Stark, H	1
Kohno, S; Nabe, T; Nakao, S; Ogawa, K; Ohata, K; Yamamura, H	1
Inoue, M; Kaya, H; Ohkubo, T; Shibata, M; Takahashi, H	1
Bynum, TE; Kronauge, JF; Morales, RE; Palitzsch, KD; Szabo, S	1
Banks, K; Merali, Z	1
Carson, CC; Davies, MG; Hagen, PO; Kim, YC; Lee, TH	1
Garbarg, M; Miller, HR; Newlands, GF; Rouleau, A; Schwartz, JC; Tuong, MD	1
Javellaud, J; Kim, LE; Oudart, N	1
Bertaccini, G; Bertini, S; Coruzzi, G; Intorre, L; Luchetti, E; Soldani, G	1
Bartolini, A; Ghelardini, C; Giotti, A; Lamberti, C; Malmberg-Aiello, P	1
Garbarg, M; Kjaer, A; Knigge, U; Rouleau, A; Warberg, J	1
Hikichi, N; Maeyama, K; Sakai, N; Sakurai, E; Watanabe, T; Yamasaki, S	1
Detzner, M; Kathmann, M; Schlicker, E; Timmerman, H	1
Endou, M; Levi, R; Poli, E	1
Maeyama, K; Onodera, K; Sakai, N; Watanabe, T; Yamazaki, S; Yanai, K	1
Kamei, C; Tasaka, K	1
Clapham, J; Kilpatrick, GJ	1
Bach, FW; Kjaer, A; Knigge, U; Madsen, EL; Søe-Jensen, P; Warberg, J	1
Bach, FW; Garbarg, M; Kjaer, A; Knigge, U; Rouleau, A; Schwartz, JC; Søe-Jensen, P; Warberg, J	1
Detzner, M; Fink, K; Göthert, M; Schlicker, E	1
Burgaud, JL; Oudart, N	1
Luo, XX	1
Garbarg, M; Krause, M; Luger, P; Rouleau, A; Schunack, W; Schwartz, JC; Stark, H	1
Assenmacher, I; Barbanel, G; Givalois, L; Ixart, G; Malaval, F; Mekaouche, M; Siaud, P	1
Allen, MC; Graham, P; Morris, G	1
Blandina, P; Cecchi, M; Giorgetti, M; Giovannini, MG; Leurs, R; Timmerman, H	1
Andrzejewski, W; Fogel, WA; Maslinski, C; Sasiak, K; Tuomisto, L	1
Bertini, S; Garbarg, M; Intorre, L; Rouleau, A; Schwartz, JC; Soldani, G	1
Del Prete, E; Lutz, TA; Scharrer, E; Walzer, B	1
Chiyotani, A; Konno, K; Nakata, J; Takeyama, K; Tamaoki, J	1
Buczko, W; Godlewski, G; Malinowska, B; Schlicker, E	1
Dimitriadou, V; Garbarg, M; Luffau, G; Miller, HR; Newlands, GJ; Rouleau, A; Schwartz, JC; Trung Tuong, MD	1
Arimura, A; Harrington, L; Schubert, ML; Vuyyuru, L	1
Jafri, MS; Moore, KA; Taylor, GE; Weinreich, D	1
Fu, LW; Longhurst, JC; Pan, HL	1
Ito, C; Onodera, K; Sakurai, E; Sato, M; Watanabe, T; Yamatodani, A; Yanai, K	1
Bast, A; Bruinier, B; Hol, BE; Jansen, HM; Krouwels, FH; Lutter, R; Out, TA	1
Archer, CB; Greaves, MW; Kavanagh, GM; Sabroe, RA	1
Akaike, N; Ishibashi, H; Munakata, M; Sakata, T; Takeshita, Y; Watanabe, T	1
Goldberg, SR; Munzar, P; Nosál, R	1
Arrang, JM; Morisset, S; Sahm, UG; Schwartz, JC; Tardivel-Lacombe, J; Traiffort, E	1
Erlander, MG; Huvar, A; Jackson, MR; Jiang, X; Lovenberg, TW; Pyati, J; Roland, BL; Wilson, SJ	1
Bertini, S; Coruzzi, G; Rouleau, A; Schwartz, JC; Soldani, G	1
Murakami, Y; Nakamura, K; Okada, S; Wang, M; Yokotani, K	1
Gao, C; Hu, Hz; Liu, S; Ren, J; Wood, JD; Xia, Y	1
Harasawa, K	1
Bielanski, W; Hahn, EG; Konturek, PC; Konturek, SJ; Kwiecien, N; Obtulowicz, W; Sito, E	1
Coupar, IM; Hemedah, M; Loiacono, R; Mitchelson, FJ	1
Blandizzi, C; Colucci, R; De Paolis, B; Del Tacca, M; Tognetti, M	1
Bauer, U; Göthert, M; Kathmann, M; Nickel, T; Sasse, A; Schlicker, E; Schunack, W; Stark, H	1
Oreland, L; Sakurai, E; Singh Jossan, S; Tanaka, Y; Watanabe, T	1
Attoub, S; Bado, A; Laigneau, JP; Lewin, MJ; Moizo, L; Sobhani, I	1
Pal, SN; Pillai, KK; Vohora, D	1
Arias, JL; Begega, A; Miranda, R; Rubio, S; Santín, LJ	1
Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Kwiecień, S; Pajdo, R; Pawlik, M; Ptak, A	1
Arias, JL; Begega, A; Rubio, S; Santin, LJ	1
Cremers, TI; De Boer, P; De Vries, JB; Liefers, H; Tran, N; Westerink, BH	1
Chotard, C; Morisset, S; Ouimet, T; Sahm, U; Schwartz, JC; Trottier, S	1
Chotard, C; Lacour, M; Mourre, C; Tighilet, B; Trottier, S	1
Fox, JL; von der Weid, PY	1
Baldi, E; Blandina, P; Bucherelli, C; Cangioli, I; Mannaioni, PF; Passani, MB	1
Bacon, KB; Center, DM; Cruikshank, WW; Gantner, F; Sakai, K; Tusche, MW	1
Furuta, H; Inoue, T; Nakano, M; Oda, N; Okano, Y; Onodera, K; Sogawa, CA; Sogawa, N; Yoneyama, T	1
Debilly, G; Gigout, S; Lin, JS; Vanni-Mercier, G	1
Coppé, MC; Gillardin, JM; Girard, P; Pansart, Y; Verniers, D	1
Foreman, J; Sodha, R; Taylor-Clark, T; Warner, B	1
Campbell, VC; Katz, JL; Kopajtic, TA; Newman, AH	1
Eckman, JR; Wagner, MC; Wick, TM	1
Alpini, G; Alvaro, D; DeMorrow, S; Fava, G; Franchitto, A; Francis, H; Gaudio, E; Glaser, S; Marzioni, M; Ueno, Y; Vaculin, B; Venter, J	1
Chen, T; Hu, J; Jia, M; Li, J; Li, M; Luo, X; Ma, X; Meng, J	1
Casali, KR; Dall'ago, P; Irigoyen, MC; Mostarda, C; Neckel, H; Quagliotto, E; Rasia-Filho, AA; Riveiro, DF	1
Hall, FS; Kitanaka, J; Kitanaka, N; Morita, Y; Nishiyama, N; Takemura, M; Tanaka, K; Tatsuta, T; Uhl, GR	1
Chepkova, A; Haas, HL; Lin, JS; Ohtsu, H; Parmentier, R; Sergeeva, OA; Yanovsky, E	1
Arrang, JM; Gbahou, F; Rouleau, A	1
Akhtar, M; Goswami, D; Jahan, K; Mahmood, D	1
Korosteleva, AS; Potapieva, NN; Shteinikov, VY; Tikhonov, DB; Tikhonova, TB	1
Timmerman, H	1
Leurs, R; Menge, WM; Timmerman, H; Vollinga, RC	1
Christiaans, JA; Gynther, J; Kotisaari, S; Kovalainen, JT; Laitinen, JT; Männistö, PT; Tuomisto, L	1
Harper, EA; Kalindjian, SB; Pether, MJ; Shankley, NP; Tozer, MJ; Watt, GF	1
Chang, H; Erlander, MG; Lovenberg, TW; Pyati, J; Wilson, SJ	1
Arrang, JM; Ganellin, CR; Gbahou, F; Ligneau, X; Morisset, S; Schunack, W; Schwartz, JC; Stark, H; Tardivel-Lacombe, J	1
Blevitt, J; Carruthers, N; Chai, W; Hofstra, CL; Jiang, X; Li, X; Liu, C; Lovenberg, TW; Ma, X; Pyati, J; Wilson, SJ	1
Alston, J; Ames, RS; Bergsma, DJ; Boyce, R; Davenport, CM; Dytko, GM; Fitzgerald, LR; Herrity, NC; Hieble, JP; Li, X; Mannan, IJ; Michalovich, D; Sarau, HM; Tan, KB; Tierney, LA; Vawter, L; Wilson, S; Wu, H; Zhu, Y	1
Anthes, JC; Bayne, M; Behan, J; Gonsiorek, W; Greene, J; Greenfeder, SA; Gustafson, EL; Hedrick, JA; Hipkin, RW; Laz, TM; Monsma, FJ; Morse, KL; Qiao, X; Shin, N; Umland, S; Wan, Y; Wang, S; West, RE	1
Audinot, V; Beauverger, P; Boutin, JA; Cogé, F; Galizzi, JP; Guénin, SP; Macia, C; Nagel, N; Ouvry, C; Renouard-Try, A; Rique, H	1
Kuei, C; Liu, C; Lovenberg, TW; Wilson, SJ	1
Hastrup, S; Rimvall, K; Wulff, BS	1
Chen, J; Liu, C; Lovenberg, TW	1
Furuichi, K; Hirano, K; Kazuta, Y; Kimura, R; Matsuda, A; Matsumoto, S; Natsume, K; Shuto, S; Yamada, S	1
Bakker, R; Cavoy, E; De Esch, IJ; Deltent, MF; Kitbunnadaj, R; Leurs, R; Lutz, M; Menge, WM; Spek, AL; Timmerman, H; Vollinga, RC; Zuiderveld, OP	1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM	1
Falus, A; Jelinek, I; Keseru, GM; Kiss, B; Kiss, R; Könczöl, A; László, V; Noszál, B; Szalai, F	1
Ishikawa, M; Kakui, N; Kato, K; Nagayama, T; Okuma, K; Oyama, M; Sato, Y; Shinei, R; Yamauchi, M; Yokoyama, F	1
Buschauer, A; Dove, S; Igel, P	1
Capet, M; Krief, S; Labeeuw, O; Reiner, D; Stark, H; Zivkovic, A	1
Grätz, L; Humphrys, LJ; Işbilir, A; Lohse, MJ; Möller, J; Nagl, M; Pockes, S; Rosier, N; Schihada, H; Seibel, U	1

Reviews

1 review(s) available for histamine and alpha-methylhistamine

Article	Year
Histamine H3 ligands: just pharmacological tools or potential therapeutic agents? Journal of medicinal chemistry, 1990, Volume: 33, Issue:1 Topics: Animals; Histamine; Histamine Antagonists; Molecular Structure; Neurotransmitter Agents; Receptors, Histamine; Receptors, Histamine H3; Structure-Activity Relationship	1990

Trials

1 trial(s) available for histamine and alpha-methylhistamine

Article	Year
The intradermal effects of the H3 receptor agonist R alpha methylhistamine in human skin. The British journal of dermatology, 1998, Volume: 138, Issue:4 Topics: Adult; Dose-Response Relationship, Drug; Female; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Intradermal Tests; Male; Methylhistamines; Skin; Terfenadine	1998

Other Studies

103 other study(ies) available for histamine and alpha-methylhistamine

Article	Year
(R)-alpha-methylhistamine augments neural, cholinergic bronchospasm in guinea pigs by histamine H1 receptor activation. European journal of pharmacology, 1992, Feb-18, Volume: 211, Issue:3 Topics: Animals; Bronchial Spasm; Bronchoconstriction; Central Nervous System; Chlorpheniramine; Cholinergic Fibers; Electric Stimulation; Guinea Pigs; Histamine; Lung; Male; Medulla Oblongata; Methylhistamines; Parasympathetic Nervous System; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H3; Synaptic Transmission; Trachea	1992
Bronchodilator action of an agonist for histamine H3-receptors in guinea pig perfused bronchioles and lung parenchymal strips. Lung, 1992, Volume: 170, Issue:2 Topics: Acetylcholine; Animals; Bronchi; Bronchoconstriction; Bronchodilator Agents; Dose-Response Relationship, Drug; Female; Fenoterol; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Methylhistamines; Muscle Relaxation; Papaverine; Perfusion; Receptors, Histamine; Receptors, Histamine H3	1992
In vivo occupancy of histamine H3 receptors by thioperamide and (R)-alpha-methylhistamine measured using histamine turnover and an ex vivo labeling technique. Biochemical pharmacology, 1992, Oct-06, Volume: 44, Issue:7 Topics: Animals; Brain Chemistry; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Methylhistamines; Mice; Piperidines; Rats; Receptors, Histamine; Receptors, Histamine H3	1992
Characterization of histamine receptor sub-types regulating prostacyclin release from human endothelial cells. British journal of pharmacology, 1992, Volume: 107, Issue:2 Topics: Cells, Cultured; Dimaprit; Endothelium, Vascular; Epoprostenol; Histamine; Histamine Agonists; Humans; Impromidine; Methylhistamines; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Thiazoles; Umbilical Veins	1992
Pharmacological characterization of histamine H3 receptors in isolated rabbit gastric glands. The American journal of physiology, 1992, Volume: 262, Issue:1 Pt 1 Topics: Aminopyrine; Animals; Carbachol; Gastric Mucosa; Histamine; Histamine Release; In Vitro Techniques; Male; Methylhistamines; Piperidines; Rabbits; Ranitidine; Receptors, Histamine H1	1992
Histamine inhibits 5-hydroxytryptamine release from the porcine small intestine: involvement of H3 receptors. Gastroenterology, 1992, Volume: 102, Issue:6 Topics: Animals; Female; Histamine; Hydroxyindoleacetic Acid; In Vitro Techniques; Intestine, Small; Male; Methylhistamines; Pyrilamine; Receptors, Histamine; Serotonin; Swine	1992
Effects of the histamine H3 receptor ligands thioperamide and (R)-alpha-methylhistamine on histidine decarboxylase activity of mouse brain. Biochemical and biophysical research communications, 1992, May-29, Volume: 185, Issue:1 Topics: Animals; Brain; Histamine; Histamine Antagonists; Histidine Decarboxylase; Injections, Intraperitoneal; Male; Methylhistamines; Mice; Mice, Inbred Strains; Piperidines; Time Factors	1992
The effects of (R) alpha-methyl histamine on the isolated guinea pig aorta. Agents and actions. Supplements, 1991, Volume: 33 Topics: Animals; Aorta; Cimetidine; Female; Guanidines; Guinea Pigs; Histamine; Histamine Antagonists; Imidazoles; Impromidine; Male; Methylhistamines; Muscle, Smooth, Vascular; Potassium; Pyrilamine; Receptors, Histamine; Receptors, Histamine H3; Vasoconstriction; Vasodilation	1991
Histamine H3-receptor activation inhibits acetylcholine release from the guinea pig myenteric plexus. Agents and actions, 1991, Volume: 33, Issue:1-2 Topics: Acetylcholine; Animals; Electric Stimulation; Guanidines; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; Imidazoles; Impromidine; Methylhistamines; Myenteric Plexus; Piperidines; Receptors, Histamine; Receptors, Histamine H3; Tritium	1991
Possible participation of histamine H3-receptors in the regulation of anaphylactic histamine release from isolated rat peritoneal mast cells. Japanese journal of pharmacology, 1994, Volume: 66, Issue:2 Topics: Anaphylaxis; Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Histamine Antagonists; Histamine Release; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Mast Cells; Methylhistamines; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Peritoneum; Piperidines; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H3	1994
Regulation of substance P release mediated via prejunctional histamine H3 receptors. European journal of pharmacology, 1995, Jan-24, Volume: 273, Issue:1-2 Topics: Animals; Capillary Permeability; Electric Stimulation; Histamine; Histamine Agonists; Histamine Antagonists; Male; Methylhistamines; Nerve Endings; Neurons, Afferent; Perfusion; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H3; Receptors, Presynaptic; Sciatic Nerve; Stimulation, Chemical; Substance P	1995
Effect of histamine on haemorrhagic mucosal lesions is related to vascular permeability in rats: studies with histamine, H1-, H2- and H3-agonists and bradykinin. European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:5 Topics: Absorption; Animals; Betahistine; Bradykinin; Capillary Permeability; Dimaprit; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Histamine; Histamine Agonists; Injections, Subcutaneous; Intubation, Gastrointestinal; Methylhistamines; Organotechnetium Compounds; Rats; Rats, Sprague-Dawley; Stomach Diseases; Sugar Acids	1995
Does the histaminergic system mediate bombesin/GRP-induced suppression of food intake? The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 2 Topics: Animals; Behavior, Animal; Bombesin; Eating; Gastrin-Releasing Peptide; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Male; Methylhistamines; Motor Activity; Peptides; Piperidines; Rats; Rats, Sprague-Dawley; Satiation; Sincalide; Thiourea	1994
Characterization and function of histamine receptors in corpus cavernosum. The Journal of urology, 1995, Volume: 153, Issue:2 Topics: Acetylcholine; Animals; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Electric Stimulation; Histamine; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Male; Methylhistamines; Muscle Contraction; Papaverine; Penis; Piperidines; Pyrilamine; Rabbits; Receptors, Histamine; Thiazoles	1995
Fasting or dexamethasone treatment reduce protease content in rat lung mast cells and modulation of histamine synthesis by H3 receptors. Agents and actions, 1994, Volume: 42, Issue:1-2 Topics: Animals; Chymases; Dexamethasone; Dose-Response Relationship, Drug; Fasting; Histamine; Histamine Agonists; Lung; Male; Mast Cells; Methylhistamines; Rats; Rats, Wistar; Receptors, Histamine H3; Serine Endopeptidases	1994
Histamine H3 agonist decreases arterial blood pressure in the guinea-pig. The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:10 Topics: Anesthesia; Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Agonists; Male; Methylhistamines; Nitric Oxide; Nitroarginine; Receptors, Histamine H3	1993
Regulation of gastric acid secretion by histamine H3 receptors in the dog: an investigation into the site of action. Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:2 Topics: Animals; Bombesin; Dogs; Female; Gastric Acid; Gastrins; Histamine; Male; Methylhistamines; Pentagastrin; Receptors, Histamine H3	1994
Role of histamine in rodent antinociception. British journal of pharmacology, 1994, Volume: 111, Issue:4 Topics: Analgesics; Animals; Histamine; Histidine; Hyperalgesia; Male; Methylhistamines; Methylhistidines; Mice; Piperidines; Pyrimethamine; Rats; Rats, Wistar; Sensory Thresholds	1994
Dehydration-induced release of vasopressin involves activation of hypothalamic histaminergic neurons. Endocrinology, 1994, Volume: 135, Issue:2 Topics: Animals; Arginine Vasopressin; Blood; Cimetidine; Dehydration; Histamine; Hypothalamus; Male; Methylhistamines; Methylhistidines; Neurons; Osmolar Concentration; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2	1994
The disposition of (R)-alpha-methylhistamine, a histamine H3-receptor agonist, in rats. The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:5 Topics: Animals; Blood-Brain Barrier; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Injections, Intravenous; Male; Methylhistamines; Rats; Rats, Wistar; Receptors, Histamine H3; Spectrometry, Fluorescence; Tissue Distribution	1994
Nordimaprit, homodimaprit, clobenpropit and imetit: affinities for H3 binding sites and potencies in a functional H3 receptor model. Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:5 Topics: Animals; Cerebral Cortex; Electric Stimulation; Histamine; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Male; Methylhistamines; Neurons; Norepinephrine; Rats; Rats, Wistar; Receptors, Histamine H3	1993
Histamine H3-receptor signaling in the heart: possible involvement of Gi/Go proteins and N-type Ca++ channels. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:1 Topics: Adrenergic Fibers; Animals; Atrial Function; Calcium Channels; Cardiotonic Agents; Drug Synergism; Electric Stimulation; GTP-Binding Proteins; Guinea Pigs; Heart; Heart Atria; Histamine; Histamine Agonists; In Vitro Techniques; Male; Methylhistamines; Myocardial Contraction; Norepinephrine; omega-Conotoxin GVIA; Peptides; Pertussis Toxin; Receptors, Histamine H3; Signal Transduction; Sympathetic Nervous System; Virulence Factors, Bordetella	1994
Effects of (S)-alpha-fluoromethylhistidine and (R)-alpha-methylhistamine on locomotion of W/Wv mice. Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:1 Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Histamine; Histamine Agonists; Histidine Decarboxylase; Locomotion; Male; Methylhistamines; Methylhistidines; Mice; Mice, Mutant Strains; Motor Activity; Receptors, Histamine H3; Spectrometry, Fluorescence	1993
Effect of histamine on memory retrieval in old rats. Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:2 Topics: Acetylcholine; Aging; Animals; Anticonvulsants; Avoidance Learning; Cerebrovascular Circulation; Cimetidine; Dose-Response Relationship, Drug; Exploratory Behavior; Histamine; Histamine Agonists; Injections, Intraventricular; Male; Memory; Methylhistamines; Motor Activity; Piperidines; Pyrilamine; Rats; Rats, Wistar	1993
Histamine H3 receptor-mediated modulation of water consumption in the rat. European journal of pharmacology, 1993, Feb-23, Volume: 232, Issue:1 Topics: Animals; Drinking; Histamine; Histamine Antagonists; Male; Methylhistamines; Nicotinic Acids; Piperidines; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H3; Tetrazoles; Triazoles	1993
Insulin/hypoglycemia-induced adrenocorticotropin and beta-endorphin release: involvement of hypothalamic histaminergic neurons. Endocrinology, 1993, Volume: 132, Issue:5 Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Cetirizine; Cimetidine; Histamine; Histamine Agonists; Histamine Antagonists; Hypoglycemia; Hypothalamus; Insulin; Male; Methylhistamines; Neurons; Pyrilamine; Pyrimidinones; Rats; Rats, Wistar	1993
Responses of anterior pituitary hormones and hypothalamic histamine to blockade of histamine synthesis and to selective activation or inactivation of presynaptic histamine H3 receptors in stressed rats. Neuroendocrinology, 1993, Volume: 57, Issue:3 Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Histamine; Histamine Antagonists; Hypoglycemia; Hypothalamus; Insulin; Kinetics; Male; Methylhistamines; Methylhistidines; Piperidines; Pituitary Hormones, Anterior; Prolactin; Rats; Rats, Wistar; Receptors, Histamine; Receptors, Histamine H3; Restraint, Physical; Stress, Physiological	1993
Histamine inhibits dopamine release in the mouse striatum via presynaptic H3 receptors. Journal of neural transmission. General section, 1993, Volume: 93, Issue:1 Topics: Animals; Calcium; Corpus Striatum; Dopamine; Electric Stimulation; Histamine; Histamine Agonists; In Vitro Techniques; Male; Methylhistamines; Mice; Mice, Inbred Strains; Piperidines; Receptors, Histamine; Receptors, Histamine H3; Stereoisomerism; Synapses; Tritium	1993
Bronchodilatation of guinea-pig perfused bronchioles induced by the H3-receptor for histamine: role of epithelium. British journal of pharmacology, 1993, Volume: 109, Issue:4 Topics: Acetylcholine; Animals; Anticonvulsants; Arginine; Bronchi; Bronchodilator Agents; Epithelium; Female; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Indomethacin; Male; Methylhistamines; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Papaverine; Perfusion; Piperidines; Prostaglandins; Receptors, Histamine H3; Tranylcypromine	1993
[Presynaptic histamine H3-receptors exist on cardiac sympathetic terminals of guinea pig]. Sheng li ke xue jin zhan [Progress in physiology], 1995, Volume: 26, Issue:3 Topics: Animals; Guinea Pigs; Heart; Histamine; Histamine Agonists; Methylhistamines; Myocardial Contraction; Norepinephrine; Presynaptic Terminals; Receptors, Histamine H3; Stimulation, Chemical; Sympathetic Nervous System	1995
New potent azomethine prodrugs of the histamine H3-receptor agonist (R)-alpha-methylhistamine containing a heteroarylphenyl partial structure. Archiv der Pharmazie, 1996, Volume: 329, Issue:4 Topics: Animals; Heterocyclic Compounds; Histamine; Histamine Agonists; Imines; Male; Methylhistamines; Mice; Molecular Structure; Prodrugs; Structure-Activity Relationship	1996
Involvement of central histamine in the early phase of ACTH and corticosterone responses to endotoxin in rats. Neuroendocrinology, 1996, Volume: 63, Issue:3 Topics: Adrenocorticotropic Hormone; Animals; Cimetidine; Corticosterone; Escherichia coli; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Kinetics; Lipopolysaccharides; Male; Median Eminence; Methylhistamines; Pyrilamine; Rats; Rats, Sprague-Dawley	1996
Histamine forming capacity (HFC) and its modulation by H3 receptor ligands in a model of bronchial hyper-responsiveness. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45, Issue:3 Topics: Animals; Binding Sites; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Injections, Intraperitoneal; Ligands; Lung; Male; Methylhistamines; Muscle, Smooth; Piperidines; Receptors, Histamine H3; Serum Albumin, Bovine; Trachea	1996
Histamine H3 receptor inhibition of K(+)-evoked release of acetylcholine from rat cortex in vivo. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45 Suppl 1 Topics: Acetylcholine; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Dimaprit; Histamine; Histamine Agonists; Histamine Antagonists; Male; Methylhistamines; Microdialysis; Neurons; Parietal Lobe; Piperidines; Potassium; Rats; Rats, Wistar; Receptors, Histamine H3; Thiazoles	1996
The effect of an ICV H3-agonist on plasma prolactin in portocaval shunted and sham operated rats. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45 Suppl 1 Topics: Analysis of Variance; Animals; Brain; Dopamine; Histamine; Histamine Agonists; Histamine Antagonists; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypothalamus; Injections, Intraventricular; Male; Methylhistamines; Norepinephrine; Piperidines; Portacaval Shunt, Surgical; Prolactin; Rats; Rats, Wistar; Receptors, Histamine H3; Serotonin	1996
Modulation of pentagastrin-induced histamine release by histamine H3 receptors in the dog. Scandinavian journal of gastroenterology, 1996, Volume: 31, Issue:7 Topics: Animals; Dogs; Female; Gastric Acid; Gastric Mucosa; Histamine; Histamine Agonists; Histamine Antagonists; Histamine Release; Male; Methylhistamines; Pentagastrin; Piperidines; Receptors, Histamine H3	1996
The histaminergic, but not the serotoninergic, system mediates amylin's anorectic effect. Peptides, 1996, Volume: 17, Issue:8 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amyloid; Animals; Appetite Depressants; Eating; Food Deprivation; Histamine; Histamine Agonists; Islet Amyloid Polypeptide; Male; Metergoline; Methylhistamines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Synaptic Transmission	1996
Histamine H2 receptor-mediated airway goblet cell secretion and its modulation by histamine-degrading enzymes. The Journal of allergy and clinical immunology, 1997, Volume: 99, Issue:2 Topics: Amine Oxidase (Copper-Containing); Animals; Asthma; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycoproteins; Guanidines; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine N-Methyltransferase; Male; Methylhistamines; Mucus; Piperidines; Pyrilamine; Recombinant Proteins; Trachea	1997
Inhibitory H3 receptors on sympathetic nerves of the pithed rat: activation by endogenous histamine and operation in spontaneously hypertensive rats. Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:2 Topics: Adrenergic Fibers; Animals; Blood Pressure; Decerebrate State; Electric Stimulation; Histamine; Histamine Agonists; Histamine Antagonists; Hypertension; Imidazoles; Male; Methylhistamines; Piperidines; Pyrimethamine; Rats; Rats, Wistar; Receptors, Histamine H3; Thiourea; Vagotomy; Vascular Resistance	1997
Functional relationships between sensory nerve fibers and mast cells of dura mater in normal and inflammatory conditions. Neuroscience, 1997, Volume: 77, Issue:3 Topics: Animals; Animals, Newborn; Capsaicin; Cerebral Cortex; Chymases; Denervation; Dura Mater; Enzyme-Linked Immunosorbent Assay; Histamine; Histamine Antagonists; Inflammation; Male; Mast Cells; Methylhistamines; Nerve Fibers; Neurons, Afferent; Nippostrongylus; Piperidines; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Serine Endopeptidases; Strongylida Infections	1997
Reciprocal inhibitory paracrine pathways link histamine and somatostatin secretion in the fundus of the stomach. The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1 Topics: Animals; Antibodies; Gastric Fundus; Gastric Mucosa; Histamine; Histamine Agonists; Histamine Antagonists; Histamine Release; In Vitro Techniques; Kinetics; Methacholine Chloride; Methylhistamines; Piperidines; Rats; Receptors, Histamine H3; Somatostatin; Virulence Factors, Bordetella	1997
Histamine H1 receptor activation blocks two classes of potassium current, IK(rest) and IAHP, to excite ferret vagal afferents. The Journal of physiology, 1997, Sep-15, Volume: 503 ( Pt 3) Topics: Action Potentials; Animals; Diphenhydramine; Electric Conductivity; Ferrets; Histamine; Histamine Agonists; Histamine H1 Antagonists; Impromidine; Male; Methylhistamines; Neurons, Afferent; Nodose Ganglion; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Pyrilamine; Receptors, Histamine H1; Thiazoles; Vagus Nerve	1997
Endogenous histamine stimulates ischemically sensitive abdominal visceral afferents through H1 receptors. The American journal of physiology, 1997, Volume: 273, Issue:6 Topics: Abdomen; Afferent Pathways; Animals; Bile Ducts; Blood Pressure; Cats; Chlorpheniramine; Dimaprit; Duodenum; Female; Gallbladder; Histamine; Histamine H1 Antagonists; Indomethacin; Ischemia; Male; Methylhistamines; Nerve Fibers; Neural Conduction; Pancreas; Pyrilamine; Receptors, Histamine H1	1997
The effect of haloperidol on the histaminergic neuron system in the rat brain. The Tohoku journal of experimental medicine, 1997, Volume: 183, Issue:4 Topics: Animals; Brain; Brain Chemistry; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Histamine; Histamine Agonists; Histidine Decarboxylase; Methylhistamines; Neurons; Rats; Rats, Wistar	1997
Histamine affects interleukin-4, interleukin-5, and interferon-gamma production by human T cell clones from the airways and blood. American journal of respiratory cell and molecular biology, 1998, Volume: 18, Issue:5 Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Albuterol; Asthma; Bronchoalveolar Lavage Fluid; Clone Cells; Cyclic AMP; Dinoprostone; Enzyme Activation; Famotidine; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Impromidine; Interferon-gamma; Interleukin-2; Interleukin-4; Interleukin-5; Lung; Methylhistamines; Piperidines; Pyridines; Ranitidine; T-Lymphocytes; Triprolidine	1998
Histamine modulates high-voltage-activated calcium channels in neurons dissociated from the rat tuberomammillary nucleus. Neuroscience, 1998, Volume: 87, Issue:4 Topics: Animals; Calcium; Calcium Channels; Calcium Channels, N-Type; Depression, Chemical; Dimaprit; Histamine; Histamine Agonists; Histamine Antagonists; Ion Channel Gating; Mammillary Bodies; Methylhistamines; Nerve Tissue Proteins; Neurons; Nicardipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Peptides; Pertussis Toxin; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H3; Spider Venoms; Tuber Cinereum; Virulence Factors, Bordetella	1998
Potentiation of the discriminative-stimulus effects of methamphetamine by the histamine H3 receptor antagonist thioperamide in rats. European journal of pharmacology, 1998, Dec-18, Volume: 363, Issue:2-3 Topics: Animals; Central Nervous System Stimulants; Discrimination Learning; Dose-Response Relationship, Drug; Drug Synergism; Histamine; Histamine Agonists; Histamine Antagonists; Male; Methamphetamine; Methylhistamines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Time Factors	1998
Atypical neuroleptics enhance histamine turnover in brain via 5-Hydroxytryptamine2A receptor blockade. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:2 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Catalepsy; Clozapine; Drug Interactions; Haloperidol; Histamine; Histamine Antagonists; Imidazoles; Male; Methylhistamines; Mice; Olanzapine; Pirenzepine; Receptor, Serotonin, 5-HT2A; Receptors, Histamine H3; Receptors, Serotonin; Serotonin Antagonists	1999
Cloning and functional expression of the human histamine H3 receptor. Molecular pharmacology, 1999, Volume: 55, Issue:6 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acid Sequence; Animals; Binding, Competitive; Cells, Cultured; Central Nervous System; Cloning, Molecular; DNA, Complementary; Histamine; Humans; Methylhistamines; Molecular Sequence Data; Rats; Receptors, Histamine H3; Receptors, Neurotransmitter; Sequence Homology, Amino Acid; Thymus Gland; Tritium	1999
Gastric antisecretory effects of compound BP 2-94: a histamine H3-receptor agonist prodrug. Digestive diseases and sciences, 1999, Volume: 44, Issue:12 Topics: Animals; Bombesin; Deoxyglucose; Dogs; Dose-Response Relationship, Drug; Gastric Mucosa; Gastrins; Histamine; Histamine Agonists; Histamine Release; Imines; Methylhistamines; Phenols; Prodrugs; Receptors, Histamine H3; Somatostatin	1999
Histamine H(3) receptor-mediated inhibition of endogenous acetylcholine release from the isolated, vascularly perfused rat stomach. European journal of pharmacology, 2000, Mar-24, Volume: 392, Issue:1-2 Topics: Acetylcholine; Animals; Atropine; Gastric Mucosa; GTP-Binding Proteins; Histamine; Imidazoles; Male; Methylhistamines; Perfusion; Pertussis Toxin; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H3; Thiourea; Vagus Nerve; Virulence Factors, Bordetella	2000
Histamine H3 receptor-mediated suppression of inhibitory synaptic transmission in the submucous plexus of guinea-pig small intestine. European journal of pharmacology, 2000, May-26, Volume: 397, Issue:1 Topics: Animals; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Intestine, Small; Male; Methylhistamines; Norepinephrine; Phentolamine; Piperidines; Receptors, Histamine H3; Submucous Plexus; Synaptic Transmission	2000
Does the histaminergic system play a role in spinal nociception? [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 2000, Volume: 75, Issue:4 Topics: Animals; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Methylhistamines; Motor Neurons; Pain; Pyrilamine; Ranitidine; Rats; Spinal Cord; Synaptic Transmission	2000
Luminal Nalpha-methyl histamine stimulates gastric acid secretion in duodenal ulcer patients via releasing gastrin. European journal of pharmacology, 2001, Jan-26, Volume: 412, Issue:2 Topics: Adult; Duodenal Ulcer; Gastric Acid; Gastrins; Helicobacter Infections; Helicobacter pylori; Histamine; Histamine Agonists; Humans; Male; Methylhistamines; Middle Aged; Statistics, Nonparametric	2001
Lack of evidence for histamine H3 receptor function in rat ileum and human colon. Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:2 Topics: Aged; Animals; Brain; Colon; Female; Guinea Pigs; Histamine; Histamine Agonists; Humans; Ileum; Male; Methylhistamines; Muscle Contraction; Rats; Rats, Wistar; Receptors, Histamine H3; RNA, Messenger; Species Specificity	2001
H3 receptor-mediated inhibition of intestinal acetylcholine release: pharmacological characterization of signal transduction pathways. Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:2 Topics: Acetylcholine; Animals; Calcium; Calcium Channels; Cholinergic Fibers; Dose-Response Relationship, Drug; Electric Stimulation; GTP-Binding Proteins; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Ileum; Male; Methylhistamines; Myenteric Plexus; Receptors, Histamine H3; Signal Transduction	2001
Novel histamine H(3)-receptor antagonists and partial agonists with a non-aminergic structure. British journal of pharmacology, 2001, Volume: 132, Issue:8 Topics: Amines; Animals; Brain Chemistry; Cerebral Cortex; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Histamine; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Methylhistamines; Mice; Norepinephrine; Perfusion; Rats; Rats, Wistar; Receptors, Histamine H3	2001
Effects of histamine H3-receptor ligands on brain monoamine oxidase in various mammalian species. Brain research, 2001, Jul-06, Volume: 906, Issue:1-2 Topics: Aged; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Hypothalamus; Imidazoles; Ligands; Macaca; Methylhistamines; Middle Aged; Monoamine Oxidase; Neurons; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Subcellular Fractions; Synaptic Transmission	2001
The H3 receptor is involved in cholecystokinin inhibition of food intake in rats. Life sciences, 2001, Jun-15, Volume: 69, Issue:4 Topics: Animals; Brain; Cholecystokinin; Dose-Response Relationship, Drug; Eating; Gastric Mucosa; Histamine; Histamine Agonists; Histamine Antagonists; Injections, Intraperitoneal; Male; Methylhistamines; Piperidines; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Receptors, Histamine H3; Sincalide; Stomach	2001
Histamine and selective H3-receptor ligands: a possible role in the mechanism and management of epilepsy. Pharmacology, biochemistry, and behavior, 2001, Volume: 68, Issue:4 Topics: Animals; Anticonvulsants; Brain; Convulsants; Drug Synergism; Epilepsy; Histamine; Histamine Agonists; Histamine Antagonists; Male; Methylhistamines; Mice; Pentylenetetrazole; Piperidines; Receptors, Histamine H3	2001
Effects of histamine precursor and (R)-alpha-methylhistamine on the avoidance response in rats. Behavioural brain research, 2001, Oct-15, Volume: 124, Issue:2 Topics: Animals; Avoidance Learning; Brain; Histamine; Histidine; Male; Mental Recall; Methylhistamines; Rats; Receptors, Histamine H3	2001
Effect of central and peripheral actions of histamine and its metabolite N-alpha methyl histamine on gastric secretion and acute gastric lesions. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2001, Volume: 52, Issue:4 Pt 1 Topics: Animals; Brain; Cytoprotection; Enterochromaffin Cells; Ethanol; Gastric Acid; Gastric Mucosa; Histamine; Injections, Intraventricular; Male; Methylhistamines; Neurons, Afferent; Rats; Regional Blood Flow	2001
Improvement of spatial memory by (R)-alpha-methylhistamine, a histamine H(3)-receptor agonist, on the Morris water-maze in rat. Behavioural brain research, 2002, Feb-01, Volume: 129, Issue:1-2 Topics: Animals; Brain Chemistry; Cues; Histamine; Histamine Agonists; Male; Maze Learning; Memory; Methylhistamines; Rats; Rats, Wistar; Space Perception; Transfer, Psychology	2002
Evidence for activation of histamine H3 autoreceptors during handling stress in the prefrontal cortex of the rat. Synapse (New York, N.Y.), 2002, Mar-15, Volume: 43, Issue:4 Topics: Animals; Autoreceptors; Biological Assay; Chromatography, High Pressure Liquid; Histamine; Histamine Agonists; Histamine Antagonists; Male; Methylhistamines; Microdialysis; Neurons; Piperidines; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Histamine H3; Stress, Physiological; Synaptic Transmission; Tetrodotoxin	2002
Effects of histamine H3 receptor agonist and antagonist on histamine co-transmitter expression in rat brain. Journal of neural transmission (Vienna, Austria : 1996), 2002, Volume: 109, Issue:3 Topics: Animals; Galanin; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Histamine; Histamine Agonists; Histamine Antagonists; Histidine Decarboxylase; Hypothalamic Area, Lateral; Hypothalamus; Imidazoles; Isoenzymes; Male; Methylhistamines; Neurons; Rats; Rats, Wistar; Receptors, Histamine H3; RNA, Messenger	2002
Betahistine dihydrochloride interaction with the histaminergic system in the cat: neurochemical and molecular mechanisms. European journal of pharmacology, 2002, Jun-20, Volume: 446, Issue:1-3 Topics: Administration, Oral; Animals; Autoradiography; Betahistine; Binding Sites; Binding, Competitive; Cats; Histamine; Histamine Agonists; Histidine Decarboxylase; Hypothalamic Area, Lateral; In Situ Hybridization; Methylhistamines; Piperidines; Radioligand Assay; Receptors, Histamine H3; RNA, Messenger; Vestibule, Labyrinth	2002
Effects of histamine on the contractile and electrical activity in isolated lymphatic vessels of the guinea-pig mesentery. British journal of pharmacology, 2002, Volume: 136, Issue:8 Topics: Animals; Dimaprit; Dose-Response Relationship, Drug; Endothelium, Lymphatic; Female; Guinea Pigs; Histamine; Histamine Agonists; In Vitro Techniques; Lymphatic System; Male; Membrane Potentials; Mesentery; Methylhistamines; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Nitroarginine; Receptors, Histamine H2; Receptors, Histamine H3	2002
Activation of histaminergic H3 receptors in the rat basolateral amygdala improves expression of fear memory and enhances acetylcholine release. The European journal of neuroscience, 2002, Volume: 16, Issue:3 Topics: Acetylcholine; Amygdala; Animals; Cholinesterase Inhibitors; Conditioning, Psychological; Dose-Response Relationship, Drug; Fear; Histamine; Histamine Agonists; Imidazoles; Male; Memory; Methylhistamines; Muscarinic Agonists; Neurons; Oxotremorine; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H3; Synaptic Transmission	2002
Histamine h(4) and h(2) receptors control histamine-induced interleukin-16 release from human CD8(+) T cells. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1 Topics: Base Sequence; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Cimetidine; Dimaprit; DNA Primers; Female; Gene Expression Regulation; Histamine; Humans; Interleukin-16; Male; Methylhistamines; Polymerase Chain Reaction; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H2; Receptors, Histamine H4	2002
The effects of histamine on the lipopolysaccharide-induced metallothionein-I mRNA expression in the mouse spleen. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2003, Volume: 52 Suppl 1 Topics: Animals; Diphenhydramine; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Lipopolysaccharides; Male; Metallothionein; Methylhistamines; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spleen	2003
Waking selective neurons in the posterior hypothalamus and their response to histamine H3-receptor ligands: an electrophysiological study in freely moving cats. Behavioural brain research, 2003, Sep-15, Volume: 144, Issue:1-2 Topics: Action Potentials; Animals; Cats; Drug Administration Schedule; Electroencephalography; Electromyography; Electrooculography; Electrophysiology; Female; Geniculate Bodies; Hippocampus; Histamine; Histamine Agonists; Histamine Antagonists; Hypothalamus, Posterior; Imidazoles; Immunohistochemistry; Male; Methylhistamines; Neurons; Thiourea; Time Factors; Wakefulness	2003
Role of the histamine system in nefopam-induced antinociception in mice. European journal of pharmacology, 2004, Oct-25, Volume: 503, Issue:1-3 Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Enzyme Inhibitors; Formaldehyde; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Male; Methylhistamines; Methylhistidines; Mice; Mice, Inbred ICR; Nefopam; Pain Measurement; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3	2004
Histamine receptors that influence blockage of the normal human nasal airway. British journal of pharmacology, 2005, Volume: 144, Issue:6 Topics: Adult; Cetirizine; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Methylhistamines; Middle Aged; Nasal Cavity; Nasal Obstruction; Ranitidine; Receptors, Histamine; Time Factors	2005
Assessment of the influence of histaminergic actions on cocaine-like effects of 3alpha-diphenylmethoxytropane analogs. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:2 Topics: Animals; Benztropine; Binding, Competitive; Brain; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Guanidines; Histamine; Histamine Agonists; Histamine H1 Antagonists; In Vitro Techniques; Male; Methylhistamines; Motor Activity; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Tropanes	2005
Histamine increases sickle erythrocyte adherence to endothelium. British journal of haematology, 2006, Volume: 132, Issue:4 Topics: Analysis of Variance; Anemia, Sickle Cell; Cell Adhesion; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Erythrocytes; Famotidine; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Methylhistamines; P-Selectin; Piperidines; Pyrilamine; Stimulation, Chemical; Thiazoles; Thiourea; Venules	2006
H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway. Laboratory investigation; a journal of technical methods and pathology, 2007, Volume: 87, Issue:5 Topics: Animals; Bile Ducts; Bile Ducts, Intrahepatic; Cell Proliferation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Down-Regulation; Drug Therapy, Combination; Gene Expression Regulation, Enzymologic; Histamine; Histamine Agonists; Hyperplasia; Ligation; Liver; Male; MAP Kinase Signaling System; Methylhistamines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Piperidines; Protein Serine-Threonine Kinases; Rats; Rats, Inbred F344; Receptor, EphA8; Receptors, Histamine H3	2007
Histamine in Macaca mulatto monkey cardiac sympathetic nerve system: a morphological and functional assessment. Autonomic neuroscience : basic & clinical, 2007, Dec-30, Volume: 137, Issue:1-2 Topics: Animals; Calcium Chloride; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Histamine; Histamine Agonists; Histamine Release; Histidine; Macaca mulatta; Male; Methylhistamines; Myocardium; Neurons; Norepinephrine; Potassium Chloride; Quinacrine; Superior Cervical Ganglion; Sympathetic Nervous System; Synaptosomes	2007
Histamine in the posterodorsal medial amygdala modulates cardiovascular reflex responses in awake rats. Neuroscience, 2008, Dec-10, Volume: 157, Issue:4 Topics: Amygdala; Analysis of Variance; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Histamine; Histamine Agonists; Male; Methylhistamines; Microinjections; Rats; Rats, Wistar; Spectrum Analysis; Wakefulness	2008
Histamine H3 receptor agonists decrease hypothalamic histamine levels and increase stereotypical biting in mice challenged with methamphetamine. Neurochemical research, 2011, Volume: 36, Issue:10 Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Histamine; Histamine Agonists; Hypothalamus; Imidazoles; Male; Methamphetamine; Methylhistamines; Mice; Motor Activity; Piperidines; Random Allocation; Stereotyped Behavior; Thiourea	2011
Histamine receptor expression, hippocampal plasticity and ammonia in histidine decarboxylase knockout mice. Cellular and molecular neurobiology, 2012, Volume: 32, Issue:1 Topics: Ammonia; Animals; Gene Expression; Hippocampus; Histamine; Histamine Agonists; Histidine Decarboxylase; Male; Methylhistamines; Mice; Mice, Knockout; Neuronal Plasticity; Receptors, Histamine; Receptors, Histamine H3; Synaptic Transmission	2012
The histamine autoreceptor is a short isoform of the H₃ receptor. British journal of pharmacology, 2012, Volume: 166, Issue:6 Topics: Animals; Arachidonic Acid; Autoreceptors; Brain; Calcimycin; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Histamine; Imidazoles; In Vitro Techniques; Male; Methylhistamines; Protein Isoforms; Rats; Rats, Wistar; Receptors, Histamine H3	2012
Histamine H3 receptor antagonists display antischizophrenic activities in rats treated with MK-801. Journal of basic and clinical physiology and pharmacology, 2016, Sep-01, Volume: 27, Issue:5 Topics: Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Histamine; Histamine H3 Antagonists; Imidazoles; Methylhistamines; Motor Activity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Thiourea	2016
Ligands of histamine receptors modulate acid-sensing ion channels. Biochemical and biophysical research communications, 2017, 09-02, Volume: 490, Issue:4 Topics: Acid Sensing Ion Channels; Animals; CHO Cells; Cricetulus; Dimaprit; Gene Expression Regulation; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Hydrogen-Ion Concentration; Ligands; Methylhistamines; Patch-Clamp Techniques; Piperidines; Receptors, Histamine; Recombinant Proteins; Signal Transduction	2017
Homologs of histamine as histamine H3 receptor antagonists: a new potent and selective H3 antagonist, 4(5)-(5-aminopentyl)-1H-imidazole. Journal of medicinal chemistry, 1995, Jan-20, Volume: 38, Issue:2 Topics: Animals; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Jejunum; Magnetic Resonance Spectroscopy; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Structure-Activity Relationship	1995
Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives. Journal of medicinal chemistry, 1999, Apr-08, Volume: 42, Issue:7 Topics: Animals; Autoradiography; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Histamine Agonists; Histamine Antagonists; Imidazoles; In Vitro Techniques; Ligands; Male; Propylamines; Rats; Rats, Wistar; Receptors, Histamine H3; Stereoisomerism; Structure-Activity Relationship	1999
From histamine to imidazolylalkyl-sulfonamides: the design of a novel series of histamine H3-receptor antagonists. Bioorganic & medicinal chemistry letters, 1999, Jul-05, Volume: 9, Issue:13 Topics: Animals; Drug Design; Guinea Pigs; Histamine Antagonists; Imidazoles; Kinetics; Models, Chemical; Receptors, Histamine H3; Sulfonamides	1999
Cloning of rat histamine H(3) receptor reveals distinct species pharmacological profiles. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:3 Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Animals; Cloning, Molecular; Dose-Response Relationship, Drug; Humans; Methylhistamines; Molecular Sequence Data; Rats; Receptors, Histamine H3; Recombinant Proteins; RNA, Messenger	2000
Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain. British journal of pharmacology, 2000, Volume: 131, Issue:7 Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Binding, Competitive; COS Cells; DNA, Complementary; Dose-Response Relationship, Drug; Histamine Antagonists; Humans; Imidazoles; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Piperidines; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, Histamine H3; Sequence Alignment; Sequence Homology, Amino Acid; Tritium	2000
Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow. Molecular pharmacology, 2001, Volume: 59, Issue:3 Topics: Adenylyl Cyclases; Amino Acid Sequence; Bone Marrow; Cloning, Molecular; Histamine; Humans; Methylhistamines; Molecular Sequence Data; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; RNA, Messenger; Sequence Homology, Amino Acid; Tissue Distribution; Tritium	2001
Cloning, expression, and pharmacological characterization of a novel human histamine receptor. Molecular pharmacology, 2001, Volume: 59, Issue:3 Topics: Amino Acid Sequence; Animals; Calcium; Cloning, Molecular; Dose-Response Relationship, Drug; Gene Expression; Genes, Reporter; Histamine; Humans; Luciferases; Mice; Molecular Sequence Data; Radioligand Assay; Receptors, Histamine; Receptors, Histamine H3; Sequence Homology, Amino Acid; Tissue Distribution; Tritium	2001
Cloning and characterization of a novel human histamine receptor. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:3 Topics: Amino Acid Sequence; Cells, Cultured; Cloning, Molecular; Histamine; Histamine Agonists; Humans; Imidazoles; Molecular Sequence Data; Radioligand Assay; Receptors, Histamine; Receptors, Histamine H3; RNA, Messenger; Sequence Homology, Amino Acid; Thiourea; Tissue Distribution; Transfection	2001
Genomic organization and characterization of splice variants of the human histamine H3 receptor. The Biochemical journal, 2001, Apr-15, Volume: 355, Issue:Pt 2 Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Calcium; CHO Cells; Cloning, Molecular; Cricetinae; DNA, Complementary; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Microscopy, Fluorescence; Molecular Sequence Data; Protein Binding; Receptors, Histamine H3; Sequence Homology, Amino Acid; Sulfur Radioisotopes	2001
Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:1 Topics: Amino Acid Sequence; Animals; Calcium; Cell Line; Cloning, Molecular; COS Cells; Cyclic AMP; DNA Fragmentation; Guinea Pigs; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity; Transfection	2001
Characteristics of recombinantly expressed rat and human histamine H3 receptors. European journal of pharmacology, 2002, Oct-18, Volume: 453, Issue:1 Topics: Animals; Cell Line; Cloning, Molecular; Histamine Agonists; Histamine Antagonists; Humans; Rats; Receptors, Histamine; Receptors, Histamine H3; Recombination, Genetic	2002
Molecular and pharmacological characterization of the mouse histamine H3 receptor. European journal of pharmacology, 2003, Apr-25, Volume: 467, Issue:1-3 Topics: Alternative Splicing; Amino Acid Sequence; Animals; Brain; Calcium; Cells, Cultured; Chlorocebus aethiops; Cloning, Molecular; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Mice; Molecular Sequence Data; Rats; Receptors, Histamine H3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology; Thiourea	2003
Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure. Journal of medicinal chemistry, 2003, May-08, Volume: 46, Issue:10 Topics: Animals; Brain; CHO Cells; Cricetinae; Cyclopropanes; Histamine Agonists; Humans; Imidazoles; In Vitro Techniques; Male; Molecular Conformation; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Stereoisomerism; Structure-Activity Relationship	2003
Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists. Journal of medicinal chemistry, 2003, Dec-04, Volume: 46, Issue:25 Topics: Binding, Competitive; Cell Line; Colorimetry; Crystallography, X-Ray; Cyclic AMP; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Ligands; Molecular Conformation; Piperidines; Pyrrolidines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship	2003
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3 Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4	2005
Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening. Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Binding, Competitive; Cell Line, Tumor; Databases, Factual; Histamine Antagonists; Humans; Ligands; Models, Molecular; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship	2008
Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active histamine type 3 receptor agonist and evaluation of its antistress activity in mice. Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Administration, Oral; Animals; Brain Chemistry; Histamine; Histamine Agonists; Hydrophobic and Hydrophilic Interactions; Methylhistamines; Mice; Receptors, Histamine; Receptors, Histamine H3; Stress, Psychological; Structure-Activity Relationship	2010
Histamine H4 receptor agonists. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Animals; Benzimidazoles; Binding Sites; Clozapine; Guanidines; Humans; Ligands; Mice; Oximes; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship	2010
Novel pyrrolidinone derivative lacks claimed histamine H European journal of medicinal chemistry, 2020, Apr-01, Volume: 191 Topics: Dose-Response Relationship, Drug; Fluorescence Polarization; HEK293 Cells; Humans; Molecular Structure; Protein Binding; Pyrrolidinones; Receptors, Histamine H3; Structure-Activity Relationship	2020
A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H Journal of medicinal chemistry, 2021, 08-12, Volume: 64, Issue:15 Topics: Binding Sites; Bioluminescence Resonance Energy Transfer Techniques; Dose-Response Relationship, Drug; Fluorescent Dyes; HEK293 Cells; Histamine H3 Antagonists; Humans; Ligands; Molecular Structure; Receptors, Histamine H3; Single Molecule Imaging; Structure-Activity Relationship	2021