histamine has been researched along with 4-(1h-imidazol-4-ylmethyl)piperidine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (10.34) | 18.2507 |
| 2000's | 20 (68.97) | 29.6817 |
| 2010's | 6 (20.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leurs, R; Menge, WM; Timmerman, H; Vollinga, RC | 1 |
| Christiaans, JA; Gynther, J; Kotisaari, S; Kovalainen, JT; Laitinen, JT; Männistö, PT; Tuomisto, L | 1 |
| Chang, H; Erlander, MG; Lovenberg, TW; Pyati, J; Wilson, SJ | 1 |
| Blevitt, J; Carruthers, N; Chai, W; Hofstra, CL; Jiang, X; Li, X; Liu, C; Lovenberg, TW; Ma, X; Pyati, J; Wilson, SJ | 1 |
| Alston, J; Ames, RS; Bergsma, DJ; Boyce, R; Davenport, CM; Dytko, GM; Fitzgerald, LR; Herrity, NC; Hieble, JP; Li, X; Mannan, IJ; Michalovich, D; Sarau, HM; Tan, KB; Tierney, LA; Vawter, L; Wilson, S; Wu, H; Zhu, Y | 1 |
| Audinot, V; Beauverger, P; Boutin, JA; Cogé, F; Galizzi, JP; Guénin, SP; Macia, C; Nagel, N; Ouvry, C; Renouard-Try, A; Rique, H | 1 |
| Hastrup, S; Rimvall, K; Wulff, BS | 1 |
| Chen, J; Liu, C; Lovenberg, TW | 1 |
| Bakker, R; Cavoy, E; De Esch, IJ; Deltent, MF; Kitbunnadaj, R; Leurs, R; Lutz, M; Menge, WM; Spek, AL; Timmerman, H; Vollinga, RC; Zuiderveld, OP | 1 |
| Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM | 1 |
| Buschauer, A; Dove, S; Igel, P | 1 |
| de Esch, IJ; de Graaf, C; Istyastono, EP; Kooistra, AJ; Leurs, R; Lim, HD; Nijmeijer, S; Roumen, L; van de Stolpe, A; Vischer, HF | 1 |
| Argyriou, A; Philippu, A; Prast, H | 1 |
| Aceves, J; Arias-Montaño, JA; Floran, B; Garcia, M; Young, JM | 1 |
| Baldi, E; Blandina, P; Bucherelli, C; Cangioli, I; Mannaioni, PF; Passani, MB | 1 |
| Chen, Z; Hu, WW; Huang, YW; Wei, EQ; Yanai, K; Zhang, LS | 1 |
| Fujii, Y; Hossen, MA; Kamei, C; Kayasuga, R; Sugimoto, Y | 1 |
| Chen, Z; Hu, WW; Jin, CL; Shen, HQ; Zhang, LS; Zhao, MH | 1 |
| Kuramasu, A; Mobarakeh, JI; Nunoki, K; Sukegawa, J; Suzuki, H; Watanabe, H; Watanabe, T; Yanagisawa, T; Yanai, K | 1 |
| Bakker, RA; Coruzzi, G; de Esch, IJ; Hashimoto, T; Hidaka, R; Kitbunnadaj, R; Leurs, R; Menge, WM; Menozzi, A; Poli, E; Timmerman, H; Yamatodani, A; Zuiderveld, OP | 1 |
| Acevedo, SF; de Esch, IJ; Raber, J | 1 |
| Arias-Montaño, JA; Garduño-Torres, B | 1 |
| Bergquist, F; Dutia, MB; Ludwig, M; Ruthven, A | 1 |
| Acevedo, SF; Pfankuch, T; Raber, J; van Meer, P | 1 |
| Alleva, L; Brabant, C; Grisar, T; Jatlow, P; Lakaye, B; Lin, JS; Ohtsu, H; Picciotto, MR; Quertemont, E; Tirelli, E | 1 |
| Hall, FS; Kitanaka, J; Kitanaka, N; Morita, Y; Nishiyama, N; Takemura, M; Tanaka, K; Tatsuta, T; Uhl, GR | 1 |
| Cremers, TI; Dremencov, E; Flik, G; Folgering, JH; Westerink, BH | 1 |
| Jin, C; Karlstedt, K; Panula, P | 1 |
| Eto, C; Fin, FE; Mascarin, L; Souza-Silva, E; Stein, T; Tonussi, CR | 1 |
29 other study(ies) available for histamine and 4-(1h-imidazol-4-ylmethyl)piperidine
| Article | Year |
|---|---|
Homologs of histamine as histamine H3 receptor antagonists: a new potent and selective H3 antagonist, 4(5)-(5-aminopentyl)-1H-imidazole.
Topics: Animals; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Jejunum; Magnetic Resonance Spectroscopy; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Structure-Activity Relationship | 1995 |
Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives.
Topics: Animals; Autoradiography; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Histamine Agonists; Histamine Antagonists; Imidazoles; In Vitro Techniques; Ligands; Male; Propylamines; Rats; Rats, Wistar; Receptors, Histamine H3; Stereoisomerism; Structure-Activity Relationship | 1999 |
Cloning of rat histamine H(3) receptor reveals distinct species pharmacological profiles.
Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Animals; Cloning, Molecular; Dose-Response Relationship, Drug; Humans; Methylhistamines; Molecular Sequence Data; Rats; Receptors, Histamine H3; Recombinant Proteins; RNA, Messenger | 2000 |
Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Bone Marrow; Cloning, Molecular; Histamine; Humans; Methylhistamines; Molecular Sequence Data; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; RNA, Messenger; Sequence Homology, Amino Acid; Tissue Distribution; Tritium | 2001 |
Cloning, expression, and pharmacological characterization of a novel human histamine receptor.
Topics: Amino Acid Sequence; Animals; Calcium; Cloning, Molecular; Dose-Response Relationship, Drug; Gene Expression; Genes, Reporter; Histamine; Humans; Luciferases; Mice; Molecular Sequence Data; Radioligand Assay; Receptors, Histamine; Receptors, Histamine H3; Sequence Homology, Amino Acid; Tissue Distribution; Tritium | 2001 |
Genomic organization and characterization of splice variants of the human histamine H3 receptor.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Calcium; CHO Cells; Cloning, Molecular; Cricetinae; DNA, Complementary; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Microscopy, Fluorescence; Molecular Sequence Data; Protein Binding; Receptors, Histamine H3; Sequence Homology, Amino Acid; Sulfur Radioisotopes | 2001 |
Characteristics of recombinantly expressed rat and human histamine H3 receptors.
Topics: Animals; Cell Line; Cloning, Molecular; Histamine Agonists; Histamine Antagonists; Humans; Rats; Receptors, Histamine; Receptors, Histamine H3; Recombination, Genetic | 2002 |
Molecular and pharmacological characterization of the mouse histamine H3 receptor.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Brain; Calcium; Cells, Cultured; Chlorocebus aethiops; Cloning, Molecular; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Mice; Molecular Sequence Data; Rats; Receptors, Histamine H3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology; Thiourea | 2003 |
Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists.
Topics: Binding, Competitive; Cell Line; Colorimetry; Crystallography, X-Ray; Cyclic AMP; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Ligands; Molecular Conformation; Piperidines; Pyrrolidines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2003 |
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4 | 2005 |
Histamine H4 receptor agonists.
Topics: Animals; Benzimidazoles; Binding Sites; Clozapine; Guanidines; Humans; Ligands; Mice; Oximes; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship | 2010 |
Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies.
Topics: Cell Line, Tumor; Histamine Antagonists; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Quantitative Structure-Activity Relationship; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Stereoisomerism; Thiourea | 2011 |
Histaminergic neurons facilitate social memory in rats.
Topics: Animals; Behavior, Animal; Histamine; Histamine Agonists; Histamine Antagonists; Histidine; Imidazoles; Male; Memory, Short-Term; Methylhistidines; Neurons; Piperidines; Rats; Rats, Sprague-Dawley; Social Behavior; Time Factors | 1996 |
Histamine H(3) receptor-mediated inhibition of depolarization-induced, dopamine D(1) receptor-dependent release of [(3)H]-gamma-aminobutryic acid from rat striatal slices.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Calcium; Dopamine; Dopamine D2 Receptor Antagonists; gamma-Aminobutyric Acid; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; In Vitro Techniques; Male; Membrane Potentials; Neostriatum; Piperidines; Potassium; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Histamine H3; Reserpine; Sulpiride; Thiourea | 2001 |
Activation of histaminergic H3 receptors in the rat basolateral amygdala improves expression of fear memory and enhances acetylcholine release.
Topics: Acetylcholine; Amygdala; Animals; Cholinesterase Inhibitors; Conditioning, Psychological; Dose-Response Relationship, Drug; Fear; Histamine; Histamine Agonists; Imidazoles; Male; Memory; Methylhistamines; Muscarinic Agonists; Neurons; Oxotremorine; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H3; Synaptic Transmission | 2002 |
Effects of endogenous histamine on seizure development of pentylenetetrazole-induced kindling in rats.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Histamine; Histamine Release; Histidine; Imidazoles; Injections, Intraventricular; Kindling, Neurologic; Male; Methylhistidines; Pentylenetetrazole; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Seizures; Thiourea | 2003 |
Histamine H3 receptors regulate vascular permeability changes in the skin of mast cell-deficient mice.
Topics: Animals; Capillary Permeability; Chlorpheniramine; Diphenhydramine; Evans Blue; Female; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Injections, Intradermal; Injections, Intravenous; Isothiuronium; Mast Cells; Mice; Mice, Mutant Strains; Piperidines; Receptors, Histamine H3; Skin; Thiourea; Tryptophan | 2003 |
[Mechanisms of the effect of brain histamine on chronic epilepsy induced by pentylenetetrazole].
Topics: Animals; Brain; Chronic Disease; Dose-Response Relationship, Drug; Epilepsy; Histamine; Histidine; Imidazoles; Male; Pentylenetetrazole; Piperidines; Rats; Rats, Sprague-Dawley; Thiourea | 2004 |
Effects of activation of central nervous histamine receptors in cardiovascular regulation; studies in H(1) and H(2) receptor gene knockout mice.
Topics: Animals; Blood Pressure; Central Nervous System; Dimaprit; Heart Rate; Histamine; Histamine Agonists; Imidazoles; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Piperidines; Receptors, Histamine | 2005 |
N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist.
Topics: Animals; Binding, Competitive; Cell Line; Chlorocebus aethiops; Cricetinae; Cricetulus; Electric Stimulation; Guinea Pigs; Histamine; Histamine Agonists; Humans; Hypothalamus; Ileum; Imidazoles; In Vitro Techniques; Male; Microdialysis; Muscle Contraction; Muscle, Smooth; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Histamine H3 | 2005 |
Sex- and histamine-dependent long-term cognitive effects of methamphetamine exposure.
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Cognition; Dopamine Uptake Inhibitors; Exploratory Behavior; Histamine; Histamine Antagonists; Imidazoles; Inhibition, Psychological; Maze Learning; Methamphetamine; Mice; Mice, Inbred C57BL; Piperidines; Reflex, Startle; Rotarod Performance Test; Sex Characteristics; Spatial Behavior | 2007 |
Homologous down-regulation of histamine H3 receptors in rat striatal slices.
Topics: Animals; Arsenicals; Binding, Competitive; Colforsin; Corpus Striatum; Cyclic AMP; Down-Regulation; Endocytosis; Enzyme Inhibitors; Histamine; Histamine Agonists; Imidazoles; Male; Organ Culture Techniques; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptor Aggregation; Receptors, Histamine H3 | 2006 |
Histaminergic and glycinergic modulation of GABA release in the vestibular nuclei of normal and labyrinthectomised rats.
Topics: Amino Acids; Animals; Ear, Inner; GABA Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Histamine; Histamine Agents; Histamine Agonists; Imidazoles; Male; Piperidines; Potassium; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Strychnine; Vestibular Nuclei | 2006 |
Role of histamine in short- and long-term effects of methamphetamine on the developing mouse brain.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Central Nervous System Stimulants; Corticosterone; Enzyme-Linked Immunosorbent Assay; Female; Histamine; Histamine H3 Antagonists; Hypothalamo-Hypophyseal System; Imidazoles; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Piperidines; Pituitary-Adrenal System; Sex Factors; Time Factors | 2008 |
Effects of the H3 receptor inverse agonist thioperamide on cocaine-induced locomotion in mice: role of the histaminergic system and potential pharmacokinetic interactions.
Topics: Animals; Area Under Curve; Biphenyl Compounds; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histamine Agonists; Histamine Release; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nitriles; Piperidines; Pyrrolidines; Receptors, Histamine H3 | 2009 |
Histamine H3 receptor agonists decrease hypothalamic histamine levels and increase stereotypical biting in mice challenged with methamphetamine.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Histamine; Histamine Agonists; Hypothalamus; Imidazoles; Male; Methamphetamine; Methylhistamines; Mice; Motor Activity; Piperidines; Random Allocation; Stereotyped Behavior; Thiourea | 2011 |
The role of cortical and hypothalamic histamine-3 receptors in the modulation of central histamine neurotransmission: an in vivo electrophysiology and microdialysis study.
Topics: Animals; Cerebral Cortex; Electrophysiology; Histamine; Histamine H3 Antagonists; Hypothalamus; Imidazoles; Male; Microdialysis; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H3; Synaptic Transmission | 2011 |
Expression of histamine receptor genes Hrh3 and Hrh4 in rat brain endothelial cells.
Topics: Animals; Blood-Brain Barrier; Brain; Cell Line; Dose-Response Relationship, Drug; Endothelial Cells; Histamine; Imidazoles; Indoles; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Piperazines; Piperidines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2013 |
Histaminergic Pharmacology Modulates the Analgesic and Antiedematogenic Effects of Spinally Injected Morphine.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Carrageenan; Cetirizine; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists, Non-Sedating; Histamine H3 Antagonists; Imidazoles; Injections, Spinal; Joints; Male; Morphine; Osteoarthritis; Piperidines; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H3; Spinal Cord | 2016 |