histamine has been researched along with 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid in 57 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (17.54) | 18.7374 |
| 1990's | 33 (57.89) | 18.2507 |
| 2000's | 12 (21.05) | 29.6817 |
| 2010's | 2 (3.51) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mayhan, WG | 1 |
| Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A | 1 |
| Jacques, CA; Johnson, M; Lee, TH; Spur, BW | 1 |
| Kanai, Y; Misawa, M | 1 |
| Bendele, AM; Fleisch, JH; Wong, WS | 1 |
| Brink, C; Gardiner, PJ; Labat, C; Norel, X | 1 |
| Francis, HP; Gardiner, PJ; Greenham, SJ; Patel, UP; Thompson, AM | 1 |
| Bonta, I; De Jongste, J; Jongejan, R; Kerrebijn, K; Raatgeep, R; Stijnen, T | 1 |
| Daikoku, M; Fukutomi, O; Inagaki, N; Kitagaki, K; Koda, A; Nagai, H; Tsuji, F | 1 |
| Bonta, IL; de Jongste, JC; Jongejan, RC; Kerrebijn, KF; Raatgeep, HC | 1 |
| Beasley, RC; Church, MK; Featherstone, RL; Harris, A; Holgate, ST; Rafferty, P; Robinson, C; Varley, JG | 1 |
| Lefer, AM; Nicolaou, KC; Ramphal, JY; Stahl, GL; Tsao, P | 1 |
| Boura, AL; King, RG; Lau, WA; Rechtman, MP | 1 |
| Inagaki, N; Koda, A; Nagai, H; Nakatomi, I; Yakuo, I | 1 |
| Aissa, J; Juan, H; Peskar, BA; Simmet, T; Sutter, D | 1 |
| Reeves, JJ; Stables, R | 1 |
| Argiolas, L; Bedetti, C; Carpi, A; Del Basso, P | 1 |
| Armour, CL; Black, JL; Johnson, PR | 1 |
| Bélanger, P; Bianchi, L; Ethier, D; Ford-Hutchinson, AW; Girard, Y; Hall, RA; Hamel, P; Hamel, R; Lord, A; Rokach, JR | 1 |
| Gordon, JL; Martin, W | 1 |
| Hull, AD; Pearce, WJ; White, CR | 1 |
| Coleman, RA; Mallett, A; Sheldrick, RL | 1 |
| Fleisch, JH; Rinkema, LE; Roman, CR; Spaethe, SM; VanAlstyne, EL | 1 |
| Borland, JA; Chester, AH; O'Neil, GS; Panda, R; Schyns, CJ; Tadjkarimi, S; Yacoub, MH | 1 |
| Borland, JA; Chester, AH; O'Neil, GS; Schyns, CJ; Tadjkarimi, S; Yacoub, MH | 1 |
| Beppu, S; Matsuda, H; Miyatake, K; Ohmori, F | 1 |
| Cai, B; Greenberg, S; Hyman, A; Kolls, J; Lippton, H; Nelson, S; Summer, WR; Wang, Y; Xie, J | 1 |
| Choppin, A; O'Connor, SE | 1 |
| Broadley, KJ; Lewis, CA | 1 |
| Högestätt, ED; Ryman, T; Zygmunt, PM | 1 |
| Arakawa, H; Kawikova, I; Löfdahl, CG; Lötvall, J; Skoogh, BE | 1 |
| Resta, TC; Walker, BR | 1 |
| Shikada, K; Tanaka, S | 1 |
| Canet, E; Dacquet, C; Dhainaut, A; Félétou, M; Lonchampt, M; Martin, CA | 1 |
| Ashida, Y; Fukuda, S; Matsumoto, T; Nagaya, H; Nakayama, T; Yamasaki, M | 1 |
| Arimura, A; Asanuma, F; Furue, Y; Yasui, K | 1 |
| Dobashi, K; Horie, T; Iizuka, K; Mori, M; Nakazawa, T; Suzuki, H; Yoshii, A | 1 |
| Kanaide, H; Kawasaki, J; Kobayashi, S; Nishimura, J; Sumiyoshi, R; Takahashi, S | 1 |
| Eidelman, DH; Michel, RP; Shi, W | 1 |
| Chan, CL; Lau, HY | 1 |
| Joos, G; Van de Voorde, J | 1 |
| Fujishima, M; Hirano, K; Kanaide, H; Kawasaki, J; Nishimura, J | 1 |
| Hirano, K; Kanaide, H; Kawakami, N; Kitamura, K; Nishimura, J; Yasui, H; Yasutsune, T | 1 |
| Hu, F; Kassouf, W; Michel, RP; Shi, W | 1 |
| Aizawa, H; Fukuyama, S; Hara, N; Inoue, H; Matsumoto, K; Nakano, H | 1 |
| Hirano, K; Ieiri, S; Kanaide, H; Nishimura, J; Suita, S | 1 |
| Calabrese, R; del Basso, P; Fabi, F; Stati, T | 1 |
| Bhattacharya, A; Cohen, ML; Schenck, KW | 1 |
| Dahlén, SE; Låstbom, L; Ryrfeldt, A; Sundström, E | 1 |
| Lao, TT; Leung, SW; Man, RY; Quan, A | 1 |
| Kraglund, K; Tottrup, A | 1 |
| Brayden, J; Morin, C; Proteau, S; Rousseau, E | 1 |
| Billington, CK; Gandhi, U; Kong, KC; Panettieri, RA; Penn, RB | 1 |
| Hiyama, Y; Ishimura, M; Kataoka, S; Maeda, T; Suda, M | 1 |
| Arimura, A; Asanuma, F; Deguchi, M; Hirano, Y; Shichijo, M; Yasui, K | 1 |
| Albadine, R; Lugnier, C; Morin, C; Rousseau, E; Senouvo, FY; Sirois, C; Yougbare, I | 1 |
| Adner, M; Al-Ameri, M; Bergman, P; Bood, J; Dahlén, SE; Delin, I; Manson, ML; Orre, AC; Säfholm, J | 1 |
57 other study(ies) available for histamine and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid
| Article | Year |
|---|---|
Responses of cerebral arterioles during chronic ethanol exposure.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine Diphosphate; Alcoholism; Animals; Arterioles; Blood Pressure; Cerebrovascular Circulation; Histamine; Male; Nitroglycerin; Pia Mater; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Reference Values; Vasodilation | 1992 |
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Animals; Bronchoconstriction; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pyridazines; Pyrilamine; Rats; Rats, Inbred Strains; Regression Analysis; SRS-A | 1992 |
The mechanism of LTE4-induced histamine hyperresponsiveness in guinea-pig tracheal and human bronchial smooth muscle, in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Animals; Atropine; Biphenyl Compounds; Bronchi; Carbachol; Electric Stimulation; Guinea Pigs; Heptanoic Acids; Histamine; Humans; In Vitro Techniques; Indomethacin; Leukotriene E4; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; SRS-A; Trachea | 1991 |
Effect of the new antiallergic drug epinastine on chemical mediator induced bronchoconstrictions in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bradykinin; Bronchoconstriction; Dibenzazepines; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Neurokinin A; Phthalazines; Piperazines; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; SRS-A; Substance P | 1991 |
Pharmacologic evaluation of A23187-induced contractions of three distinct preparations of guinea pig lung parenchymal strips.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcimycin; Drug Interactions; Guinea Pigs; Histamine; Hydroxyurea; In Vitro Techniques; Indomethacin; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Pyrilamine; SRS-A | 1992 |
Inhibitory effects of BAY u3405 on prostanoid-induced contractions in human isolated bronchial and pulmonary arterial muscle preparations.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Bronchi; Carbazoles; Histamine; Humans; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Prostaglandin Antagonists; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Pulmonary Artery; Sulfonamides; Thromboxanes | 1991 |
BAY u3405 an antagonist of thromboxane A2- and prostaglandin D2-induced bronchoconstriction in the guinea-pig.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Oral; Aerosols; Animals; Blood Pressure; Bronchoconstriction; Carbazoles; Guinea Pigs; Histamine; In Vitro Techniques; Injections, Intravenous; Male; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Serotonin; SRS-A; Sulfonamides; Thromboxane A2; Thromboxanes | 1991 |
Effect of epithelial denudation, inflammatory mediators and mast cell activation on the sensitivity of isolated human airways to methacholine.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aged; Aged, 80 and over; Antibodies, Anti-Idiotypic; Dinoprost; Epithelium; Histamine; Humans; Hypersensitivity; Immunoglobulin E; In Vitro Techniques; Inflammation; Kinetics; Lung; Male; Mast Cells; Methacholine Chloride; Middle Aged; Muscle Contraction; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; SRS-A | 1991 |
The effect of ONO-3708, a novel TxA2 receptor antagonist, on U-46619-induced contraction of guinea pig and human tracheal strips in vitro and on bronchoconstriction in guinea pigs in vivo.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Bronchoconstriction; Guinea Pigs; Histamine; Humans; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Respiration; SRS-A; Thromboxane A2; Trachea | 1991 |
Additive effect of epithelial denudation and low levels of inflammatory mediators on the sensitivity of isolated human airways to methacholine.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Bronchi; Dose-Response Relationship, Drug; Epithelium; Histamine; Histological Techniques; Humans; In Vitro Techniques; Methacholine Chloride; Osmolar Concentration; Prostaglandin Endoperoxides, Synthetic | 1990 |
Effect of a thromboxane receptor antagonist on PGD2- and allergen-induced bronchoconstriction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adolescent; Adult; Animals; Asthma; Biphenyl Compounds; Bronchi; Dinoprost; Guinea Pigs; Heptanoic Acids; Histamine; Humans; Male; Methacholine Compounds; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2 | 1989 |
Pharmacologic profile of lipoxins A5 and B5: new biologically active eicosanoids.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Biological Factors; Eicosapentaenoic Acid; Guinea Pigs; Histamine; In Vitro Techniques; Lipoxins; Lung; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Prostaglandin Endoperoxides, Synthetic; Radioimmunoassay | 1989 |
Synergistic potentiation by captopril and propranolol of bradykinin-induced bronchoconstriction in the guinea-pig.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Arrhythmia Agents; Arachidonic Acids; Biphenyl Compounds; Bradykinin; Bronchi; Captopril; Drug Synergism; Guinea Pigs; Histamine; In Vitro Techniques; Injections, Intravenous; Male; Muscle Contraction; Muscle, Smooth; Propranolol; Prostaglandin Endoperoxides, Synthetic | 1989 |
The role of thromboxane A2 (TxA2) in allergic cutaneous reactions and the effect of (E)-3-[p-(1H-imidazol-1-ylmethyl) phenyl]-2-propenoic acid hydrochloride (OKY-046), a TxA2 synthetase inhibitor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acrylates; Animals; Dermatitis, Contact; Female; Histamine; Hypersensitivity, Delayed; Male; Methacrylates; Mice; Mice, Inbred BALB C; Prostaglandin Endoperoxides, Synthetic; Rabbits; Rats; Rats, Inbred Strains; Serotonin; SRS-A; Thromboxane A2; Thromboxane-A Synthase | 1989 |
Modulation of the contractile activity of the guinea-pig lung parenchymal strip by exogenous 5,8,11,14,17-eicosapentaenoic acid.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anaphylaxis; Animals; Chromatography, High Pressure Liquid; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Lung; Male; Prostaglandin Endoperoxides, Synthetic; SRS-A; Umbelliferones | 1987 |
Effects of indomethacin, piroxicam and selected prostanoids on gastric acid secretion by the rat isolated gastric mucosa.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; Female; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Indomethacin; Piroxicam; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Secretory Rate; Thiazines | 1985 |
Arachidonic acid and pulmonary function in heart-lung-preparation of guinea-pig: modulation by PCO2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Carbon Dioxide; Guinea Pigs; Heart; Hemodynamics; Histamine; In Vitro Techniques; Indomethacin; Lung; Muscle Contraction; Muscle, Smooth, Vascular; Prostaglandin Endoperoxides, Synthetic; Respiration; Serotonin; Thromboxane A2; Vasoconstriction | 1987 |
Potentiation of contraction of rabbit airway smooth muscle by some cyclooxygenase products.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchi; Carbachol; Dinoprost; Electric Stimulation; Histamine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Prostaglandins D; Rabbits | 1988 |
L-641,953 (R-8-fluoro-dibenzo[b, f]thiepin-3-carboxylic acid-5-oxide): a novel thromboxane-prostaglandin endoperoxide antagonist.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchi; Dibenzothiepins; Dogs; Female; Gallbladder; Guinea Pigs; Histamine; Humans; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Thromboxanes; Trachea | 1987 |
Differential calcium dependence of contractile responses and 86Rb efflux from the rabbit aorta induced by vasoactive stimuli.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Aorta, Abdominal; Calcium; Female; Histamine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Prostaglandin Endoperoxides, Synthetic; Rabbits; Rubidium | 1983 |
Endothelium-derived relaxing factor and cyclic GMP-dependent vasorelaxation in human chorionic plate arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Arteries; Bradykinin; Calcimycin; Chorion; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Female; Histamine; Humans; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Pregnancy; Prostaglandin Endoperoxides, Synthetic; Serotonin; Substance P; Thromboxane A2; Vasoconstrictor Agents; Vasodilation | 1994 |
EP4-receptors and cyclic AMP in pig venous smooth muscle: evidence with agonists and the EP4-antagonist, AH22921.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Biphenyl Compounds; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Histamine; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Receptors, Prostaglandin E; Saphenous Vein; Swine; Thromboxane A2; Vasoconstrictor Agents; Venae Cavae | 1995 |
Contraction of guinea pig inferior vena cava by eicosanoids.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetophenones; Animals; Eicosanoids; Guinea Pigs; Histamine; Hydroxyquinolines; In Vitro Techniques; Leukotriene C4; Leukotriene E4; Male; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; SRS-A; Tetrazoles; Thromboxane A2; Vena Cava, Inferior | 1993 |
Effect of mode of application of papaverine on the contractile response of the internal mammary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Dopamine; Dose-Response Relationship, Drug; Histamine; Humans; In Vitro Techniques; Injections, Intra-Arterial; Mammary Arteries; Middle Aged; Muscle Contraction; Norepinephrine; Papaverine; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Serotonin; Thromboxane A2; Time Factors; Vasoconstrictor Agents | 1994 |
Vasoconstrictor profile of the inferior epigastric artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Abdominal Muscles; Adolescent; Adult; Arteries; Dopamine; Endothelins; Female; Histamine; Humans; Male; Mammary Arteries; Middle Aged; Norepinephrine; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Serotonin; Vasoconstrictor Agents | 1993 |
Different modes of endothelin-1 action in pressor response in vivo and pulmonary parenchymal contraction in vitro in the guinea pig.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Pressure; Dose-Response Relationship, Drug; Endothelins; Female; Guinea Pigs; Histamine; Indomethacin; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Phospholipid Ethers; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2 | 1993 |
Tumor necrosis factor-alpha inhibits endothelium-dependent relaxation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Cattle; Endothelium, Vascular; Histamine; Ibuprofen; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Pentoxifylline; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Veins; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 1993 |
Pre-contraction with histamine and U46619 unmasks a 5-HT1-like receptor in rabbit renal artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Prostaglandin Endoperoxides, Synthetic; Rabbits; Receptors, Serotonin; Renal Artery; Serotonin; Serotonin Receptor Agonists; Vasoconstrictor Agents | 1993 |
Airway hyper- or hyporeactivity to inhaled spasmogens 24 h after ovalbumin challenge of sensitized guinea-pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Administration, Inhalation; Airway Resistance; Animals; Asthma; Atropine; Bronchial Spasm; Bronchoconstrictor Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Methacholine Chloride; Ovalbumin; Plethysmography, Whole Body; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Regional differences in endothelium-dependent relaxation in the rat: contribution of nitric oxide and nitric oxide-independent mechanisms.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aorta; Arginine; Benzopyrans; Calcimycin; Calcitonin Gene-Related Peptide; Cromakalim; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Femoral Artery; Histamine; Ionophores; Liver; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Rats; Rats, Sprague-Dawley; Renal Artery; Thromboxane A2; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1995 |
U46619 (a thromboxane A2 mimetic) induces airflow obstruction and airway plasma extravasation in the guinea pig: the role of histamine, cyclooxygenase metabolites, leukotrienes and PAF.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Dose-Response Relationship, Drug; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Histamine; Leukotrienes; Male; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Pulmonary Ventilation; Thromboxane A2; Trachea; Vasoconstrictor Agents | 1996 |
Chronic hypoxia selectively augments endothelium-dependent pulmonary arterial vasodilation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Biological Factors; Endothelins; Endothelium, Vascular; Histamine; Hypoxia; Ionomycin; Ionophores; Male; Muscle, Smooth, Vascular; Nitric Oxide; Oligopeptides; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstrictor Agents; Vasodilation | 1996 |
Effect of the K+ channel openers NIP-121 and cromakalim on melittin-induced relaxation of guinea-pig isolated trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzopyrans; Cromakalim; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Epithelium; Guinea Pigs; Histamine; Indomethacin; Leukotriene D4; Male; Melitten; Muscle Relaxation; Muscle, Smooth; Oxadiazoles; Phospholipases A; Phospholipases A2; Piperidines; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Thromboxane A2; Trachea | 1996 |
In vitro pharmacological effects of S 12370 (2-[4-benzhydryloxypiperidinoethyl]isoxindole; an antibronchoconstrictor agent) in normal and sensitized tissue.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arachidonic Acid; Benzhydryl Compounds; Binding, Competitive; Electric Stimulation; Guinea Pigs; Heart; Histamine; Leukotriene D4; Lung; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Ovalbumin; Oxindoles; Prostaglandin Endoperoxides, Synthetic; Rats; Receptors, Adrenergic, beta; Serotonin; Substance P; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Involvement of thromboxane A2 and histamine in experimental allergic rhinitis of guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antigens; Benzoquinones; Capillary Permeability; Guinea Pigs; Heptanoic Acids; Histamine; Histamine H1 Antagonists; Male; Nasal Mucosa; Phthalazines; Prostaglandin Antagonists; Prostaglandin Endoperoxides, Synthetic; Rhinitis, Allergic, Seasonal; Thromboxane A2 | 1997 |
Involvement of thromboxane A2 in antigen-induced nasal blockage in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Animals; Antigens; Bridged Bicyclo Compounds; Diphenhydramine; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Male; Nasal Obstruction; Ovalbumin; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Thromboxane B2 | 1997 |
Receptor-dependent G protein-mediated Ca2+ sensitization in canine airway smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aluminum; Animals; Bacterial Toxins; Calcium; Calcium-Binding Proteins; Calponins; Carbachol; Cell Membrane Permeability; Dogs; Endothelin-1; Escin; Female; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hemolysin Proteins; Histamine; Isometric Contraction; Male; Microfilament Proteins; Muscle, Smooth; Peptide Fragments; Phorbol 12,13-Dibutyrate; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Muscarinic; Serotonin; Thromboxane A2; Trachea | 1997 |
Diadenosine polyphosphates directly relax porcine coronary arterial smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Caffeine; Calcium; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dinucleoside Phosphates; Histamine; In Vitro Techniques; Muscle, Smooth, Vascular; Potassium Channel Blockers; Swine; Vasodilation | 1997 |
Differential relaxant responses of pulmonary arteries and veins in lung explants of guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Guinea Pigs; Histamine; Image Processing, Computer-Assisted; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Organ Culture Techniques; Pulmonary Artery; Pulmonary Veins; Vasoconstrictor Agents | 1997 |
Effects of prostanoid receptor agonists on immunologically-activated rat peritoneal mast cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Dinoprost; Dinoprostone; Epoprostenol; Histamine; Histamine Release; Immunoglobulin E; Male; Mast Cells; Oxytocics; Peritoneal Cavity; Platelet Aggregation Inhibitors; Prostaglandin D2; Prostaglandins, Synthetic; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Structure-Activity Relationship; Vasoconstrictor Agents | 1998 |
Regionally different influence of contractile agonists on isolated rat airway segments.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bradykinin; Bronchi; Carbachol; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Organ Specificity; Rats; Rats, Inbred F344; Rats, Wistar; Respiratory Physiological Phenomena; Serotonin; Species Specificity; Trachea | 1998 |
Mechanisms of vasorelaxation induced by troglitazone, a novel antidiabetic drug, in the porcine coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Calcium; Chromans; Coronary Vessels; Cytosol; Histamine; Hypoglycemic Agents; In Vitro Techniques; Isometric Contraction; Potassium; Swine; Thiazoles; Thiazolidinediones; Troglitazone; Vasodilation; Vasodilator Agents | 1998 |
Vasorelaxation and inhibition of the voltage-operated Ca2+ channels by FK506 in the porcine coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Caffeine; Calcium; Calcium Channels; Central Nervous System Stimulants; Coronary Vessels; Electric Stimulation; Endothelin-1; Histamine; Immunosuppressive Agents; In Vitro Techniques; Isotonic Solutions; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium; Swine; Tacrolimus; Vasoconstrictor Agents; Vasodilation | 1999 |
Altered reactivity of pulmonary vessels in postobstructive pulmonary vasculopathy.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Ligation; Lung; Male; Muscle, Smooth, Vascular; Neovascularization, Physiologic; Nitroprusside; Pulmonary Artery; Pulmonary Veins; Serotonin; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2000 |
Cyclooxygenase-2 participates in the late phase of airway hyperresponsiveness after ozone exposure in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Animals; Benzenesulfonates; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Guinea Pigs; Histamine; Immunohistochemistry; Isoenzymes; Male; Oxazoles; Oxidants, Photochemical; Ozone; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxane A2 | 2000 |
Alteration of the [Ca(2+)](i)-force relationship during the vasorelaxation induced by a Ca(2+) channel blocker SR33805 in the porcine coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Caffeine; Calcium; Calcium Channel Blockers; Coronary Vessels; Dose-Response Relationship, Drug; Histamine; In Vitro Techniques; Indoles; Myosin Light Chains; Phosphorylation; Potassium; Sulfones; Swine; Time Factors; Vasoconstrictor Agents; Vasodilation | 2000 |
Nitric oxide (NO) modulation of PAF-induced cardiopulmonary action: interaction between NO synthase and cyclo-oxygenase-2 pathways.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Animals; Arginine; Blood Pressure; Cardiac Output; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart; Heart Rate; Histamine; Indomethacin; Isoenzymes; Lung; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitrobenzenes; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pulmonary Ventilation; Serotonin; Signal Transduction; Sulfonamides | 2001 |
Amplification of sumatriptan-induced contraction in rabbit saphenous vein but not in basilar artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Basilar Artery; Drug Synergism; Histamine; Male; Nitrendipine; Rabbits; Saphenous Vein; Serotonin Receptor Agonists; Sumatriptan; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
Interactions among three classes of mediators explain antigen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchoconstriction; Cysteine; Drug Interactions; Guinea Pigs; Histamine; Histamine Antagonists; Leukotriene D4; Leukotrienes; Lung; Male; Ovalbumin; Perfusion; Pyrilamine; Thromboxanes | 2003 |
5-hydroxytryptamine and thromboxane A2 as physiologic mediators of human umbilical artery closure.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II; Bradykinin; Endothelin-1; Female; Histamine; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxygen; Phenylephrine; Pregnancy; Serotonin; Thromboxane A2; Umbilical Arteries; Vasoconstriction; Vasoconstrictor Agents | 2003 |
Endothelium-dependent responses in small human mesenteric arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Biological Factors; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Histamine; Humans; In Vitro Techniques; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Potassium; Potassium Channels; Splanchnic Circulation; Substance P | 2004 |
Organ-cultured airway explants: a new model of airway hyperresponsiveness.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Apoptosis; Biomechanical Phenomena; Bronchi; Bronchial Hyperreactivity; Calcium; Calcium Signaling; Carbachol; Electrophysiology; Female; Guinea Pigs; Histamine; Indomethacin; Male; Membrane Potentials; Models, Biological; Norepinephrine; Organ Culture Techniques; Time Factors; Trachea | 2005 |
Cooperative mitogenic signaling by G protein-coupled receptors and growth factors is dependent on G(q/11).
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Cells, Cultured; Epidermal Growth Factor; Growth Substances; GTP-Binding Protein alpha Subunits, Gq-G11; Histamine; Humans; Muscle, Smooth; Receptors, G-Protein-Coupled; Respiratory Mucosa; Signal Transduction; Thrombin; Vasoconstrictor Agents | 2006 |
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Acetylcholine; Albuterol; Animals; Atropine; Benzoquinones; Carbachol; Chromones; Cyclopropanes; Dinoprost; Drug Evaluation, Preclinical; Guinea Pigs; Heptanoic Acids; Histamine; In Vitro Techniques; Indoles; Indomethacin; Ketanserin; Ketotifen; Leukotriene Antagonists; Leukotriene D4; Male; Muscle Contraction; Muscle, Smooth; Phenylcarbamates; Powders; Procaterol; Prostaglandin Antagonists; Prostaglandin D2; Quinolines; Receptors, Thromboxane A2, Prostaglandin H2; Serotonin; Substance P; Sulfides; Sulfonamides; Tosyl Compounds; Trachea; Tryptophan | 2006 |
Contribution of prostaglandin D2 via prostanoid DP receptor to nasal hyperresponsiveness in guinea pigs repeatedly exposed to antigen.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Intranasal; Allergens; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Histamine; Male; Nasal Mucosa; Nasal Obstruction; Nose; Ovalbumin; Pressure; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Rhinitis, Allergic, Perennial; Thiophenes; Time Factors | 2008 |
NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anti-Inflammatory Agents; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Cell Fractionation; Cell Separation; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Histamine; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Isoenzymes; Methacholine Chloride; Middle Aged; Muscle Proteins; Myosin-Light-Chain Phosphatase; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase 4 Inhibitors; Phosphoprotein Phosphatases; Pneumonia; Rolipram; Tissue Culture Techniques; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 2011 |
Prostaglandin E2 inhibits mast cell-dependent bronchoconstriction in human small airways through the E prostanoid subtype 2 receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Asthma; Azetidines; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Bronchoconstriction; Cells, Cultured; Dinoprost; Dinoprostone; Fatty Acids, Unsaturated; Histamine; Humans; Hydrazines; Immunoglobulin E; In Vitro Techniques; Mast Cells; Molecular Targeted Therapy; Naphthalenes; Phenylbutyrates; Prostaglandin D2; Receptors, Prostaglandin; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Receptors, Thromboxane | 2015 |