histamine has been researched along with 1-(5-isoquinolinesulfonyl)-2-methylpiperazine in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (17.14) | 18.7374 |
| 1990's | 18 (51.43) | 18.2507 |
| 2000's | 9 (25.71) | 29.6817 |
| 2010's | 2 (5.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Baux, G; Fossier, P; Tauc, L | 1 |
| Asano, K; Iizuka, H; Ito, F; Takahashi, H; Tamura, T; Tsutsui, M | 1 |
| Adeagbo, AS; Triggle, CR | 1 |
| Abe, S; Hirano, K; Kanaide, H; Nakamura, M | 1 |
| Bast, A; Leurs, R; Timmerman, H | 1 |
| Bomsztyk, K; Ostrowski, J | 1 |
| Abe, S; Hirano, K; Kai, H; Kanaide, H; Kodama, M; Nakamura, M | 1 |
| Endou, M; Hattori, Y; Kanno, M; Shirota, M | 1 |
| Souhrada, JF; Souhrada, M | 1 |
| Halldórsson, H; Thorgeirsson, G | 1 |
| el-Fakahany, EE; Lai, WS | 1 |
| Hashioka, T | 1 |
| Droogmans, G; Nilius, B; Oike, M; Schwartz, G | 1 |
| Black, JL; Yang, KX | 1 |
| Crockett, J; Levine, RA; Nandi, J | 1 |
| Kuga, T; Mitsuoka, W; Nakamura, M; Satoh, S; Shimokawa, H; Tagawa, H; Takeshita, A; Tomoike, H | 1 |
| Hashimoto, Y; Iizuka, H; Ishida-Yamamoto, A; Takahashi, H | 1 |
| Bosche, MC; Levine, RA; Nandi, J; Rotker, JD; Strapko, A | 1 |
| Cortijo, J; De Diego, A; Esplugues, J; Morcillo, EJ; Perpiñá, M; Villagrasa, V | 1 |
| Chock, PB; Huang, CY; Tekle, E; Zhu, DM | 1 |
| Cortijo, J; de Diego, A; Morcillo, EJ; Perpina, M; Villagrasa, V | 1 |
| Bristow, DR; Zamani, MR | 1 |
| Barnes, PJ; Dupont, LJ; Mak, JC; Pype, JL; Verleden, GM | 1 |
| Kim, SW; Levine, RA; Loo, A; Nandi, J | 1 |
| Blandizzi, C; Colucci, R; Del Tacca, M; Tognetti, M | 1 |
| Hishinuma, S; Ogura, K | 1 |
| Mikoshiba, K; Muto, Y; Nagao, T; Urushidani, T; Yamada, M | 1 |
| Katoh, Y; Kawamura, T; Morimoto-Ishizuka, T; Niimi, M; Sawada, M; Takemori, H; Yamamoto, Y; Yamatodani, A | 1 |
| Asano, T; Ikegaki, I; Sato, S; Shimokawa, H | 1 |
| Ito, M; Kaibuchi, K; Kandabashi, T; Kunihiro, I; Matoba, T; Morikawa, K; Mukai, Y; Shimokawa, H; Takahashi, S; Takeshita, A | 1 |
| Ichikawa, A; Mikura, S; Satoh, N; Takasu, Y; Tanaka, S | 1 |
| Burnstock, G; Smith, NC | 1 |
| Faraci, FM; Heistad, DD; Watanabe, Y | 1 |
| Akatsu, C; Hishinuma, S; Sato, Y; Shoji, M | 1 |
35 other study(ies) available for histamine and 1-(5-isoquinolinesulfonyl)-2-methylpiperazine
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Regulation of transmitter release by presynaptic receptors at a cholinergic neuro-neuronal synapse.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Aplysia; Calcium Channels; FMRFamide; Histamine; Invertebrate Hormones; Isoquinolines; Neuropeptides; Piperazines; Protein Kinase C; Synapses | 1992 |
Desensitization of the epidermal adenylate cyclase system: agonists and phorbol esters desensitize by independent mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alkaloids; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Epidermis; Epinephrine; Histamine; Isoquinolines; Pertussis Toxin; Piperazines; Receptors, Adrenergic, beta; Receptors, Histamine; Skin; Staurosporine; Swine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Effects of some inorganic divalent cations and protein kinase C inhibitors on endothelium-dependent relaxation in rat isolated aorta and mesenteric arteries.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Alkaloids; Animals; Aorta, Thoracic; Calcium; Cations, Divalent; Endothelium, Vascular; Histamine; In Vitro Techniques; Isoquinolines; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrendipine; Nitroprusside; Norepinephrine; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine | 1991 |
Temporal changes in the calcium-force relation during histamine-induced contractions of strips of the coronary artery of the pig.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Coronary Vessels; Cytosol; Female; Fura-2; Histamine; In Vitro Techniques; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Piperazines; Protein Kinase C; Spectrometry, Fluorescence; Swine | 1991 |
Ebselen inhibits contractile responses of guinea-pig parenchymal lung strips.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoles; Catechols; Cyclooxygenase Inhibitors; Guinea Pigs; Histamine; Indomethacin; Isoindoles; Isoquinolines; Lung; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Organoselenium Compounds; Piperazines; Potassium Chloride; Selenium; Thiazoles | 1990 |
Interaction of signal transduction pathways in mediating acid secretion by rat parietal cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Bucladesine; Cell Membrane; Diglycerides; Female; Gastric Acid; Histamine; Isoquinolines; Parietal Cells, Gastric; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1989 |
Endothelin-induced Ca-independent contraction of the porcine coronary artery.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Caffeine; Calcium; Coronary Vessels; Dose-Response Relationship, Drug; Egtazic Acid; Endothelins; Endothelium, Vascular; Histamine; Isoquinolines; Kinetics; Muscle Contraction; Peptides; Piperazines; Protein Kinase C; Spectrometry, Fluorescence; Swine | 1989 |
Dissociation of phosphoinositide hydrolysis and positive inotropic effect of histamine mediated by H1-receptors in guinea-pig left atria.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carbamates; Chlorides; Electric Stimulation; Female; Guinea Pigs; Heart; Histamine; Hydrolysis; In Vitro Techniques; Isoquinolines; Lithium; Lithium Chloride; Male; Myocardial Contraction; Myocardium; Neomycin; Phenylcarbamates; Phorbol Esters; Phosphatidylinositols; Piperazines; Receptors, Histamine H1; Type C Phospholipases | 1989 |
The role of protein kinase-C in sensitization and antigen response of airway smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Antibody Specificity; Antigens; Carbazoles; Guinea Pigs; Histamine; Immunization; Immunoglobulin G; Indoles; Indomethacin; Isoquinolines; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Ovalbumin; Piperazines; Potassium Chloride; Protein Kinase C; Tetradecanoylphorbol Acetate; Trachea | 1989 |
Desensitization of inositol phosphate production after agonist stimulation of endothelial cells is not mediated by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Histamine; Humans; Inositol Phosphates; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; Sugar Phosphates; Tetradecanoylphorbol Acetate; Thrombin | 1989 |
Phorbol ester-induced inhibition of cyclic GMP formation mediated by muscarinic receptors in murine neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Carbachol; Cell Line; Cyclic GMP; Dose-Response Relationship, Drug; Histamine; Isoquinolines; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Piperazines; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1987 |
Recepto-secretory mechanism in histamine-stimulated amylase release from rat parotid gland.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amylases; Animals; Azepines; Calmodulin; Cimetidine; Culture Techniques; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Isoquinolines; Male; Myosin-Light-Chain Kinase; Parotid Gland; Piperazines; Protein Kinase C; Pyrilamine; Rats; Rats, Wistar; Sulfonamides | 1995 |
Histamine-activated, non-selective cation currents and Ca2+ transients in endothelial cells from human umbilical vein.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium Channels; Cations, Divalent; Electrophysiology; Endothelium, Vascular; Female; Histamine; Humans; In Vitro Techniques; Ion Channels; Isoquinolines; Membrane Potentials; Muscle, Smooth, Vascular; Nystatin; Phorbol Esters; Piperazines; Pregnancy; Protein Kinase C; Signal Transduction; Umbilical Veins | 1993 |
The involvement of protein kinase C in the contraction of human airway smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Bronchi; Histamine; Humans; In Vitro Techniques; Indoles; Isoquinolines; Maleimides; Muscle Contraction; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Staurosporine | 1995 |
A possible role of protein kinase C in augmenting H+ secretion by nonsteroidal anti-inflammatory drugs.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bucladesine; Histamine; Ibuprofen; Isoquinolines; Male; Piperazines; Protein Kinase C; Protons; Rabbits; Rana catesbeiana; Tetradecanoylphorbol Acetate | 1994 |
Hyperreactivity of aortic smooth muscle to serotonin is related to the presence of atheroma in Watanabe heritable hyperlipidaemic rabbits.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Arteriosclerosis; Calcium; Culture Techniques; Female; Histamine; Hyperlipidemias; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phorbol Esters; Piperazines; Protein Kinase Inhibitors; Rabbits; Serotonin | 1993 |
Activators of protein kinase C but not of phospholipase C modulate adenylate cyclase-responses of normal pig epidermis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenylyl Cyclases; Animals; Bradykinin; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Epidermal Growth Factor; Epidermis; Epinephrine; Histamine; Isoquinolines; Keratinocytes; Piperazines; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1995 |
Effects of cyclic adenosine monophosphate-dependent protein kinase and calcium-dependent protein kinase modulators on stimulated gastric acid secretion in the perfused rat stomach.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Administration, Oral; Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gastric Acid; Histamine; Injections, Intravenous; Isoquinolines; Male; Naphthalenes; Pentagastrin; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetradecanoylphorbol Acetate | 1995 |
Effects of phorbol 12,13-diacetate and its influence on spasmogenic responses in normal and sensitized guinea-pig trachea.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium; Diuretics; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth; Phorbol Esters; Piperazines; Potassium Chloride; Protein Kinase C; Serotonin; Trachea; Vasodilator Agents; Verapamil | 1995 |
Reversible phosphorylation as a controlling factor for sustaining calcium oscillations in HeLa cells: Involvement of calmodulin-dependent kinase II and a calyculin A-inhibitable phosphatase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Binding Sites; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Enzyme Inhibitors; Ethers, Cyclic; HeLa Cells; Histamine; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoquinolines; Maleimides; Marine Toxins; Molecular Sequence Data; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Piperazines; Protein Kinase C; Receptors, Cytoplasmic and Nuclear; Ryanodine; Spectrometry, Fluorescence; Staurosporine; Sulfonamides | 1996 |
H-7, a protein kinase C inhibitor, inhibits spontaneous tone and spasmogenic responses in normal and sensitized guinea pig trachea.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Chloride; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Histamine; In Vitro Techniques; Isoquinolines; Male; Muscle, Smooth; Piperazines; Potassium Chloride; Protein Kinase C; Trachea | 1995 |
The histamine H1 receptor in GT1-7 neuronal cells is regulated by calcium influx and KN-62, a putative inhibitor of calcium/calmodulin protein kinase II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bradykinin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Receptors, Histamine H1; Signal Transduction; Tumor Cells, Cultured | 1996 |
Regulation of H1-receptor coupling and H1-receptor mRNA by histamine in bovine tracheal smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cattle; Cimetidine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Indoles; Indomethacin; Maleimides; Muscle, Smooth; Pyrilamine; Receptors, Histamine H1; RNA, Messenger; Trachea | 1998 |
Expression and characterization of protein kinase C in isolated rabbit parietal cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aminopyrine; Animals; Calcium; Cimetidine; Enzyme Inhibitors; Histamine; In Vitro Techniques; Isoenzymes; Male; Parietal Cells, Gastric; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protons; Rabbits; Staurosporine; Tetradecanoylphorbol Acetate | 1999 |
Histamine H(3) receptors mediate inhibition of noradrenaline release from intestinal sympathetic nerves.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Adrenergic alpha-Antagonists; Animals; Calcium; Colforsin; Dose-Response Relationship, Drug; Ethylmaleimide; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Ileum; In Vitro Techniques; Intestinal Mucosa; Intestines; Male; Muscle, Smooth; Myenteric Plexus; Nifedipine; Norepinephrine; omega-Conotoxins; Pertussis Toxin; Phenols; Receptors, Histamine H3; Rolipram; Sympathetic Nervous System; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetrodotoxin; Virulence Factors, Bordetella; Yohimbine | 2000 |
Ca(2+)/calmodulin-mediated regulation of the desensitizing process in G(q) protein-coupled histamine H(1) receptor-mediated Ca(2+) responses in human U373 MG astrocytoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Astrocytoma; Calcineurin Inhibitors; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cyclosporine; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Histamine; Histamine H1 Antagonists; Humans; Kinetics; Okadaic Acid; Piperidines; Pyrilamine; Ranitidine; Receptors, Histamine H1; Sulfonamides; Tacrolimus; Tumor Cells, Cultured | 2000 |
A proposed mechanism for the potentiation of cAMP-mediated acid secretion by carbachol.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Aminopyrine; Animals; Bucladesine; Calcium; Calcium Channels; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Carbon Radioisotopes; Cyclic AMP; Cytochalasin D; Cytoskeleton; Drug Interactions; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Maleimides; Parietal Cells, Gastric; Protein Kinase C; Rabbits; Receptors, Cytoplasmic and Nuclear; Stomach | 2001 |
Histamine production by cultured microglial cells of the mouse.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Inhibitors; Histamine; Histidine Decarboxylase; Lipopolysaccharides; Mice; Microglia; RNA, Messenger | 2001 |
Antiischemic properties of fasudil in experimental models of vasospastic angina.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angina Pectoris; Animals; Coronary Vasospasm; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Endothelins; Histamine; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Protein Serine-Threonine Kinases; Rabbits; Rats; Rats, Wistar; rho-Associated Kinases; Swine; Time Factors; Vasodilation; Vasodilator Agents; Vasopressins | 2001 |
Involvement of rho-kinase in agonists-induced contractions of arteriosclerotic human arteries.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Coronary Artery Disease; Dose-Response Relationship, Drug; Enzyme Inhibitors; Histamine; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle Proteins; Muscle, Smooth, Vascular; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; rho-Associated Kinases; Serotonin; Succinates; Thoracic Arteries; Vasoconstriction; Vasodilator Agents | 2002 |
Antigen-independent induction of histamine synthesis by immunoglobulin E in mouse bone marrow-derived mast cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antigens; Calcimycin; Calcium Signaling; Enzyme Inhibitors; Estrenes; Female; Histamine; Histidine Decarboxylase; Immunoglobulin E; In Vitro Techniques; Interleukin-3; Mast Cells; Mice; Mice, Inbred BALB C; Protein Kinase C; Pyrrolidinones; Receptors, IgE; RNA, Messenger; src-Family Kinases; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2002 |
Mechanisms underlying postjunctional synergism between responses of the vas deferens to noradrenaline and ATP.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Cantharidin; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Histamine; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Muscle, Smooth; Naphthalenes; Norepinephrine; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Prazosin; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; rho-Associated Kinases; Vas Deferens | 2004 |
Activation of Rho-associated kinase during augmented contraction of the basilar artery to serotonin after subarachnoid hemorrhage.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Basilar Artery; Disease Models, Animal; Enzyme Activation; Histamine; Intracellular Signaling Peptides and Proteins; Male; Motor Activity; Muscle Contraction; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Rabbits; rho-Associated Kinases; Serotonin; Subarachnoid Hemorrhage | 2005 |
The affinity of histamine for Gq protein-coupled histamine H(1)-receptors is predominantly regulated by their internalization in human astrocytoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Astrocytoma; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Chlorides; Clathrin; Endocytosis; G-Protein-Coupled Receptor Kinases; GTP-Binding Protein alpha Subunits, Gq-G11; Histamine; Histamine H1 Antagonists; Humans; Receptors, Histamine H1; Tumor Cells, Cultured; Zinc Compounds | 2012 |