hippuristanol and rocaglamide

hippuristanol has been researched along with rocaglamide* in 1 studies

Other Studies

1 other study(ies) available for hippuristanol and rocaglamide

Article	Year
Inhibitors of translation targeting eukaryotic translation initiation factor 4A. Methods in enzymology, 2012, Volume: 511 The RNA helicases eIF4AI and eIF4AII play key roles in recruiting ribosomes to mRNA templates during eukaryotic translation initiation. Small molecule inhibitors of eIF4AI and eIF4AII have been useful for chemically dissecting their role in translation in vitro and in vivo. Here, we describe a screen performed on a small focused library of kinase inhibitors to identify a novel helicase inhibitor. We describe assays that have been critical for characterizing novel RNA helicase inhibitors. Topics: Animals; Anthracenes; Benzofurans; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Humans; Macrolides; Perylene; Protein Kinase Inhibitors; Sterols; Thiazoles	2012

Article

Year

Inhibitors of translation targeting eukaryotic translation initiation factor 4A.

Methods in enzymology, 2012, Volume: 511

The RNA helicases eIF4AI and eIF4AII play key roles in recruiting ribosomes to mRNA templates during eukaryotic translation initiation. Small molecule inhibitors of eIF4AI and eIF4AII have been useful for chemically dissecting their role in translation in vitro and in vivo. Here, we describe a screen performed on a small focused library of kinase inhibitors to identify a novel helicase inhibitor. We describe assays that have been critical for characterizing novel RNA helicase inhibitors.

Topics: Animals; Anthracenes; Benzofurans; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Humans; Macrolides; Perylene; Protein Kinase Inhibitors; Sterols; Thiazoles

2012