hippuric acid and indican

hippuric acid has been researched along with indican in 59 studies

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (8.47)	18.7374
1990's	3 (5.08)	18.2507
2000's	14 (23.73)	29.6817
2010's	31 (52.54)	24.3611
2020's	6 (10.17)	2.80

Authors

Authors	Studies
Hosokawa, A; Motojima, M; Muraki, T; Yamato, H; Yoshioka, T	1
Asaba, H; Deguchi, T; Mori, S; Ohtsuki, S; Otagiri, M; Takanaga, H; Terasaki, T	1
Deguchi, T; Endou, H; Kusuhara, H; Otagiri, M; Sugiyama, Y; Takadate, A	1
Benet, LZ; Frassetto, L; Huang, Y; Sun, H	1
Hashimoto, N; Hayashi, H; Ise, M; Maeda, K; Miyazaki, T; Niwa, T; Uehara, Y	1
Gerlag, PG; Peeters, JA; Schoots, AC	1
Kawashima, Y	1
Mabuchi, H; Nakahashi, H	2
Gulyassy, PF; Jarrard, E; Stanfel, L	1
Dasgupta, A; Malik, S	1
Bernard, BF; de Jong, M; Docter, R; Hennemann, G; Krenning, EP; Lim, CF	1
De Smet, R; Dhondt, A; Duym, P; Lameire, N; Lesaffer, G; Vanholder, R	1
De Smet, R; Lameire, N; Vanholder, R	1
Dasgupta, A; Paul, A; Wells, A	1
Ivanov, AI; Korneeva, LN; Lindup, WE; Maslenny, VN; Nikolaev, VG; Niwa, T; Sarnatskaya, VV; Tjia, J; Yushko, LA	1
Buoncristiani, U; De Smet, R; Fagugli, RM; Lameire, N; Vanholder, R	1
Berland, Y; Brunet, P; Cerini, C; Dou, L	1
Deguchi, T; Kouno, Y; Otagiri, M; Takadate, A; Terasaki, T	1
Davilas, A; Koupparis, M; Macheras, P; Valsami, G	1
Grinenko, DV; Mikhalovsky, SV; Nikolaev, AV; Nikolaev, VG; Sakhno, LA; Sarnatskaya, VV; Yushko, LA	1
Kawai, K; Nishii, R; Nishio, T; Takamura, N; Tokunaga, J; Yoshimoto, M	1
Ezawa, A; Itoh, Y; Kikuchi, K; Murakami, K; Niwa, T; Tateoka, R	2
Fridolin, I; Jerotskaja, J; Lauri, K; Luman, M; Tanner, R	1
Hwang, GS; Kim, HS; Kim, KB; Kim, YJ; Kwack, SJ; Lee, BM; Park, KL; Ryu, DH; Yang, JY	1
Hostetter, TH; Li, Y; Luo, FY; Marquez, IO; Meyer, TW; Plummer, NS; Tambra, S	1
Abe, T; Akiyama, Y; Ito, S; Kikuchi, K; Mishima, E; Nagao, S; Soga, T; Suzuki, C; Suzuki, T; Takeuchi, Y; Tanemoto, M; Toyohara, T; Yoshihara, D	1
Boelaert, J; Eloot, S; Glorieux, G; Lynen, F; Sandra, P; Van Landschoot, M; Vanholder, R; Waterloos, MA	1
Aronov, PA; Hostetter, TH; Meyer, TW; Plummer, NS; Sirich, TL	1
Borneman, Z; Gerritsen, KG; Glorieux, G; Joles, JA; Stamatialis, D; Sun, J; Swart, PC; Tijink, MS; Vanholder, R; Wessling, M; Wester, M	1
Furukubo, T; Hiraoka, S; Hosoda, S; Izumi, S; Minegaki, T; Miyoshi, A; Nagano, Y; Nishiguchi, K; Shiraishi, A; Tsujimoto, M; Yamakawa, T	1
Funk, BA; Hostetter, TH; Meyer, TW; Plummer, NS; Sirich, TL	1
Dhondt, A; Eloot, S; Glorieux, G; Neirynck, N; Van Biesen, W; Vanholder, R	1
Bi, K; Chen, X; Gu, L; Jiang, Y; Lu, H; Wang, X; Zhang, Y	1
Barnes, KJ; Miners, JO; Polasek, TM; Rowland, A	1
Furukubo, T; Izumi, S; Minegaki, T; Nishiguchi, K; Oda, T; Ogino, H; Shinmoto, T; Tachiki, H; Tsujimoto, M; Uchiyama, H; Yamakawa, T; Yoshida, T	1
Avance, J; Denson, D; Harris, R; Stec, DF; Stothers, C; Voziyan, P; Wang, S	1
Banerjee, T; Coresh, J; Hostetter, TH; Hwang, S; Melamed, ML; Meyer, TW; Parekh, RS; Powe, NR; Shafi, T	1
Deltombe, O; Dhondt, A; Eloot, S; Glorieux, G; Massy, Z; Van Biesen, W	1
Bao, Y; Gao, P; Hong, CS; Jia, W; Luo, P; Tu, Y; Wei, L; Xu, G; Yin, P; Yu, H; Zhang, P; Zhao, X; Zhuang, Z	1
Bi, KS; Chen, XH; Gu, L; Shi, H; Wei, Z; Zhang, R	1
Hoofnagle, AN; Kestenbaum, BR; Kratz, M; Newitt, R; Rivara, MB; Tracy, RP; Weigle, DS; Zelnick, LR	1
Behr, C; Fabian, E; Kamp, H; Krennrich, G; Mellert, W; Peter, E; Rietjens, IMCM; Strauss, V; van Ravenzwaay, B; Walk, T	1
de Loor, H; Deltombe, O; Dhondt, A; Eloot, S; Glorieux, G; Meijers, B; Van Biesen, W	1
Banerjee, T; Coresh, J; Hostetter, TH; Hwang, S; Melamed, ML; Meyer, TW; Plummer, NS; Powe, NR; Shafi, T; Sirich, TL	1
Delrue, W; Dhondt, A; Eloot, S; Glorieux, G; Roels, S; Schepers, E; Van Biesen, W; Vanholder, R	1
Charalambopoulou, G; Gerritsen, KGF; Giasafaki, D; Pavlenko, D; Stamatialis, D; Steriotis, T; van Geffen, E	1
Ding, F; Li, Y; Liu, T; Ma, S; Shi, Y; Tian, H; Wang, W; Wang, Y; Zhu, Q	1
Chinnappa, S; Glorieux, G; Mooney, A; Tu, YK; Vanholder, R; Yeh, YC	1
Deltombe, O; Eloot, S; Glorieux, G; Marzouki, S; Masereeuw, R; Schneditz, D	1
Nolin, TD; Prokopienko, AJ; Stubbs, JR; West, RE	1
Chen, P; Fang, JT; Hsiao, YS; Huang, CH; Juang, RS; Liu, ZW; Sahoo, S; Yen, SC	1
André, C; Bennis, Y; Bodeau, S; Caillard, P; Choukroun, G; Cluet, Y; Kamel, S; Liabeuf, S; Maizel, J; Titeca-Beauport, D	1
Chung, FM; Hsuan, CF; Hung, WC; Lee, TL; Lee, YJ; Lu, YC; Tsai, IT; Wang, CP; Wei, CT; Wu, CC; Yu, TH	1
Lee, S; Mair, RD; Meyer, TW; Plummer, NS; Sirich, TL	1
Abe, E; Alvarez, JC; Fabresse, N; Lamy, E; Larabi, IA; Massy, ZA; Rigothier, C	1
Balint, L; Bob, F; Cretu, OM; Gadalean, F; Glavan, M; Ienciu, S; Jianu, DC; Milas, O; Mogos, M; Petrica, L; Socaciu, AI; Socaciu, C; Suteanu-Simulescu, A; Vlad, A	1
Alvarez, JC; Bénard, A; Catros, S; Combe, C; Larabi, I; Massy, Z; Quintin, O; Rigothier, C; Samot, J	1

Reviews

2 review(s) available for hippuric acid and indican

Article	Year
Protein-bound uremic solutes: the forgotten toxins. Kidney international. Supplement, 2001, Volume: 78 Topics: Animals; Cresols; Furans; Hippurates; Homocysteine; Humans; Indican; Intestinal Mucosa; Kinetics; Propionates; Protein Binding; Proteins; Renal Dialysis; Toxins, Biological; Uremia	2001
Protein-bound uremic retention solutes. Advances in renal replacement therapy, 2003, Volume: 10, Issue:4 Topics: Animals; Blood Proteins; Cresols; Furans; Hippurates; Homocysteine; Humans; Indican; Propionates; Renal Dialysis; Uremia	2003

Trials

3 trial(s) available for hippuric acid and indican

Article	Year
Behavior of non-protein-bound and protein-bound uremic solutes during daily hemodialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002, Volume: 40, Issue:2 Topics: Creatinine; Cresols; Cross-Over Studies; Female; Furans; Hippurates; Humans; Indican; Indoleacetic Acids; Male; Membranes, Artificial; Middle Aged; Propionates; Protein Binding; Renal Dialysis; Solutions; Toxins, Biological; Urea; Uremia; Uric Acid	2002
Influences of haemodialysis on the binding sites of human serum albumin: possibility of an efficacious administration plan using binding inhibition. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:7 Topics: Adult; Aged; Barbiturates; Binding Sites; Carbon Radioisotopes; Diazepam; Diuretics; Fatty Acids, Nonesterified; Female; Furans; Furosemide; Hippurates; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Propionates; Protein Binding; Renal Dialysis; Serum Albumin; Treatment Outcome; Warfarin	2008
Results of the HEMO Study suggest that p-cresol sulfate and indoxyl sulfate are not associated with cardiovascular outcomes. Kidney international, 2017, Volume: 92, Issue:6 Topics: Adult; Aged; Cardiovascular Diseases; Cresols; Female; Glutamine; Hippurates; Humans; Indican; Kidney Failure, Chronic; Longitudinal Studies; Male; Middle Aged; Renal Dialysis; Risk Factors; Serum Albumin; Sulfuric Acid Esters; Uremia	2017

Other Studies

54 other study(ies) available for hippuric acid and indican

Article	Year
Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake. British journal of pharmacology, 2002, Volume: 135, Issue:2 Topics: Animals; Binding Sites; Cell Line; Cell Line, Transformed; Dose-Response Relationship, Drug; Free Radicals; Growth Inhibitors; Humans; Kidney Tubules, Proximal; Opossums; Organic Anion Transport Protein 1; p-Aminohippuric Acid; Rats; Toxins, Biological; Uremia	2002
Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney. Kidney international, 2002, Volume: 61, Issue:5 Topics: Animals; Anions; Biological Transport; Dose-Response Relationship, Drug; Female; Furans; Indican; Kidney; Kidney Failure, Chronic; Male; Oocytes; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Probenecid; Propionates; Rats; Rats, Wistar; Toxins, Biological; Tritium; Uremia; Uricosuric Agents; Xenopus laevis	2002
Characterization of uremic toxin transport by organic anion transporters in the kidney. Kidney international, 2004, Volume: 65, Issue:1 Topics: Animals; DNA, Complementary; GABA Modulators; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Tubules, Proximal; LLC-PK1 Cells; Male; Organ Culture Techniques; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Pravastatin; Rats; Rats, Sprague-Dawley; Swine; Toxins, Biological; Transfection; Uremia	2004
Effects of uremic toxins on hepatic uptake and metabolism of erythromycin. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:11 Topics: Animals; Cell Line; Dogs; Dose-Response Relationship, Drug; Erythromycin; Furans; Indican; Liver; Male; Propionates; Rats; Rats, Wistar; Uremia	2004
Suppressed serum and urine levels of indoxyl sulfate by oral sorbent in experimental uremic rats. American journal of nephrology, 1992, Volume: 12, Issue:4 Topics: Adsorption; Animals; Carbon; Chromatography, High Pressure Liquid; Female; Hippurates; Indican; Intestine, Small; Kidney; Liver; Oxides; Rats; Rats, Sprague-Dawley; Uremia	1992
Effect of hemodialysis on serum concentrations of HPLC-analyzed accumulating solutes in uremia. Nephron, 1989, Volume: 53, Issue:3 Topics: Adult; Aged; Blood Chemical Analysis; Blood Proteins; Chromatography, High Pressure Liquid; Female; Hematocrit; Hippurates; Humans; Indican; Male; Middle Aged; Protein Binding; Renal Dialysis; Uremia	1989
[Study on the uremic protein binding inhibitors as uremic toxin: toxic effect on erythroid colony formation, lymphocyte blast formation and renal function]. Nihon Jinzo Gakkai shi, 1989, Volume: 31, Issue:11 Topics: Animals; Cell Division; Cells, Cultured; Erythroid Precursor Cells; Hippurates; In Vitro Techniques; Indican; Kidney Tubules; Lymphocyte Activation; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Sodium; Uremia	1989
Profiling of endogenous ligand solutes that bind to serum proteins in sera of patients with uremia. Nephron, 1986, Volume: 43, Issue:2 Topics: Blood Proteins; Chromatography, High Pressure Liquid; Hippurates; Hot Temperature; Humans; Indican; Indoleacetic Acids; Ligands; Protein Binding; Ultrafiltration; Uremia	1986
Roles of hippurate and indoxyl sulfate in the impaired ligand binding by azotemic plasma. Advances in experimental medicine and biology, 1987, Volume: 223 Topics: Blood Proteins; Hippurates; Humans; Indican; Protein Binding; Salicylates; Salicylic Acid; Toxins, Biological; Uremia	1987
Displacement by anionic drugs of endogenous ligands bound to albumin in uremic serum. Therapeutic drug monitoring, 1988, Volume: 10, Issue:3 Topics: Binding Sites; Furans; Hippurates; Humans; Indican; Indoleacetic Acids; Propionates; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Uremia; Warfarin	1988
Fast atom bombardment mass spectrometric determination of the molecular weight range of uremic compounds that displace phenytoin from protein binding: absence of midmolecular uremic toxins. American journal of nephrology, 1994, Volume: 14, Issue:3 Topics: Drug Interactions; Guanidine; Guanidines; Hippurates; Humans; In Vitro Techniques; Indican; Methylguanidine; Phenytoin; Protein Binding; Renal Dialysis; Spectrometry, Mass, Fast Atom Bombardment; Succinates; Toxins, Biological; Uremia	1994
A furan fatty acid and indoxyl sulfate are the putative inhibitors of thyroxine hepatocyte transport in uremia. The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:2 Topics: Adsorption; Animals; Biological Transport; Cells, Cultured; Furans; Hippurates; Humans; Indican; Iodides; Kidney Failure, Chronic; Liver; Male; Propionates; Rats; Rats, Wistar; Renal Dialysis; Thyroxine; Uremia	1993
Intradialytic removal of protein-bound uraemic toxins: role of solute characteristics and of dialyser membrane. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2000, Volume: 15, Issue:1 Topics: Aged; Aged, 80 and over; Creatinine; Cresols; Female; Furans; Hippurates; Humans; Indican; Kidneys, Artificial; Male; Membranes, Artificial; Middle Aged; Propionates; Protein Binding; Renal Dialysis; Toxins, Biological; Urea; Uremia	2000
Uremic sera contain inhibitors that block digitoxin-valproic acid interaction. The American journal of the medical sciences, 2001, Volume: 322, Issue:4 Topics: Anticonvulsants; Binding Sites; Binding, Competitive; Cardiotonic Agents; Digitoxin; Drug Interactions; Hippurates; Humans; In Vitro Techniques; Indican; Protein Binding; Serum Albumin; Uremia; Valproic Acid	2001
Effect of protein-bound uraemic toxins on the thermodynamic characteristics of human albumin. Biochemical pharmacology, 2002, Apr-01, Volume: 63, Issue:7 Topics: Albumins; Furans; Hippurates; Humans; Indican; Propionates; Thermodynamics	2002
Differential contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in vivo renal uptake of uremic toxins in rats. Pharmaceutical research, 2005, Volume: 22, Issue:4 Topics: Animals; Biological Transport; Carbon Radioisotopes; Estrone; Furans; Hippurates; Indican; Indoleacetic Acids; Kidney; Male; Metabolic Clearance Rate; Organic Anion Transport Protein 1; Organic Cation Transport Proteins; p-Aminohippuric Acid; Penicillin G; Propionates; Rats; Rats, Wistar; Serum; Tritium	2005
In-vitro study on the competitive binding of diflunisal and uraemic toxins to serum albumin and human plasma using a potentiometric ion-probe technique. The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:11 Topics: Algorithms; Animals; Binding, Competitive; Blood Proteins; Calibration; Diflunisal; Hippurates; Humans; Indican; Indoleacetic Acids; Ion-Selective Electrodes; Potentiometry; Serum Albumin; Serum Albumin, Bovine; Technology, Pharmaceutical; Toxins, Biological; Uremia	2006
New approaches to the removal of protein-bound toxins from blood plasma of uremic patients. Artificial cells, blood substitutes, and immobilization biotechnology, 2007, Volume: 35, Issue:3 Topics: Adsorption; Binding Sites; Calorimetry, Differential Scanning; Charcoal; Furans; Hemoperfusion; Hippurates; Humans; Hydrogen-Ion Concentration; Indican; Membranes, Artificial; Plasma; Propionates; Protein Binding; Reference Values; Renal Dialysis; Serum Albumin; Toxins, Biological; Treatment Outcome; Uremia	2007
Metabolomic analysis of uremic toxins by liquid chromatography/electrospray ionization-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Jun-15, Volume: 878, Issue:20 Topics: Animals; Chromatography, Liquid; Cresols; Disease Models, Animal; Hippurates; Humans; Indican; Kidney; Kidney Failure, Chronic; Male; Metabolomics; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Sulfuric Acid Esters; Toxins, Biological	2010
HPLC study of uremic fluids related to optical dialysis adequacy monitoring. The International journal of artificial organs, 2010, Volume: 33, Issue:2 Topics: Aged; Aged, 80 and over; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Creatinine; Dialysis Solutions; Female; Hippurates; Humans; Indican; Male; Middle Aged; Renal Dialysis; Spectrophotometry, Ultraviolet; Urea; Uremia; Uric Acid	2010
Metabolomic search for uremic toxins as indicators of the effect of an oral sorbent AST-120 by liquid chromatography/tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Nov-01, Volume: 878, Issue:29 Topics: Adsorption; Animals; Carbon; Chromatography, Liquid; Hippurates; Indican; Kidney Failure, Chronic; Male; Metabolomics; Oxides; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Toxins, Biological; Uremia	2010
Toxicometabolomics of urinary biomarkers for human gastric cancer in a mouse model. Journal of toxicology and environmental health. Part A, 2010, Volume: 73, Issue:21-22 Topics: Adenocarcinoma; Animals; Biomarkers, Tumor; Cell Line, Tumor; Citric Acid; Discriminant Analysis; Disease Models, Animal; Hippurates; Humans; Indican; Ketoglutaric Acids; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methylamines; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Principal Component Analysis; Stomach Neoplasms; Xenograft Model Antitumor Assays	2010
Contribution of residual function to removal of protein-bound solutes in hemodialysis. Clinical journal of the American Society of Nephrology : CJASN, 2011, Volume: 6, Issue:2 Topics: Adult; Aged; Cresols; Female; Glomerular Filtration Rate; Hippurates; Humans; Indican; Kidney; Kidney Diseases; Linear Models; Male; Middle Aged; Models, Biological; Practice Guidelines as Topic; Protein Binding; Renal Dialysis; Sulfuric Acid Esters; Time Factors; Treatment Outcome; Urea	2011
Metabolomic profiling of the autosomal dominant polycystic kidney disease rat model. Clinical and experimental nephrology, 2011, Volume: 15, Issue:5 Topics: Aconitic Acid; Animals; Disease Models, Animal; Electrophoresis, Capillary; Hippurates; Humans; Indican; Male; Mass Spectrometry; Metabolomics; Polycystic Kidney, Autosomal Dominant; Rats; Renal Insufficiency	2011
A novel UPLC-MS-MS method for simultaneous determination of seven uremic retention toxins with cardiovascular relevance in chronic kidney disease patients. Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:6 Topics: Cardiovascular Diseases; Case-Control Studies; Chromatography, High Pressure Liquid; Cresols; Female; Furans; Glucuronides; Hippurates; Humans; Indican; Indoleacetic Acids; Male; Propionates; Renal Insufficiency, Chronic; Severity of Illness Index; Sulfuric Acid Esters; Tandem Mass Spectrometry; Uremia; Uric Acid	2013
Numerous protein-bound solutes are cleared by the kidney with high efficiency. Kidney international, 2013, Volume: 84, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Chromatography, Liquid; Cresols; Female; Hippurates; Humans; Indican; Kidney; Kidney Diseases; Male; Metabolic Clearance Rate; Middle Aged; Protein Binding; Renal Dialysis; Sulfuric Acid Esters; Tandem Mass Spectrometry	2013
Mixed matrix hollow fiber membranes for removal of protein-bound toxins from human plasma. Biomaterials, 2013, Volume: 34, Issue:32 Topics: Adsorption; Cresols; Hippurates; Humans; Indican; Membranes, Artificial; Microscopy, Electron, Scanning; Sulfuric Acid Esters; Toxins, Biological; Ultrafiltration	2013
Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease. Toxins, 2013, Aug-19, Volume: 5, Issue:8 Topics: Cell Line, Tumor; Cytochrome P-450 CYP3A; Erythromycin; Furans; Hippurates; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Liver; Microsomes, Liver; Pregnane X Receptor; Propionates; Receptors, Calcitriol; Receptors, Steroid; RNA, Messenger; Steroid Hydroxylases; Toxins, Biological; Vitamin D; Vitamin D3 24-Hydroxylase	2013
Prominent accumulation in hemodialysis patients of solutes normally cleared by tubular secretion. Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:3 Topics: Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Cresols; Female; Glutamine; Hippurates; Humans; Indican; Kidney Failure, Chronic; Kidney Tubules; Male; Middle Aged; Models, Statistical; Renal Dialysis	2014
Does the adequacy parameter Kt/V(urea) reflect uremic toxin concentrations in hemodialysis patients? PloS one, 2013, Volume: 8, Issue:11 Topics: Aged; Aged, 80 and over; beta 2-Microglobulin; Biomarkers; Creatinine; Cresols; Diabetes Mellitus; Female; Furans; Glucuronides; Hippurates; Humans; Indican; Indoleacetic Acids; Male; Middle Aged; Multivariate Analysis; Propionates; Renal Dialysis; Sulfuric Acid Esters; Treatment Outcome; Urea; Uremia; Uric Acid	2013
Determination of 12 potential nephrotoxicity biomarkers in rat serum and urine by liquid chromatography with mass spectrometry and its application to renal failure induced by Semen Strychni. Journal of separation science, 2014, Volume: 37, Issue:9-10 Topics: Animals; Biomarkers; Chromatography, Liquid; Citric Acid; Creatinine; Drugs, Chinese Herbal; Glycine; Guanidines; Hippurates; Indican; Indoleacetic Acids; Kynurenic Acid; Male; Mass Spectrometry; Medicine, Chinese Traditional; Molecular Structure; Plant Extracts; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Succinates; Taurine; Uric Acid; Xanthurenates	2014
Inhibition of human drug-metabolising cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in vitro by uremic toxins. European journal of clinical pharmacology, 2014, Volume: 70, Issue:9 Topics: Benzyl Alcohol; Cresols; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Hippurates; Humans; Indican; Microsomes, Liver; Toxins, Biological; Uremia	2014
Uremic toxins enhance statin-induced cytotoxicity in differentiated human rhabdomyosarcoma cells. Toxins, 2014, Sep-03, Volume: 6, Issue:9 Topics: Apoptosis; Cell Differentiation; Cell Line, Tumor; Cell Survival; Drug Synergism; Furans; Hippurates; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indican; Indoleacetic Acids; Pravastatin; Propionates; Rhabdomyosarcoma; Simvastatin; Toxins, Biological; Uremia	2014
Alterations of urinary metabolite profile in model diabetic nephropathy. Biochemical and biophysical research communications, 2015, Jan-09, Volume: 456, Issue:2 Topics: Aconitic Acid; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycine; Hippurates; Indican; Keto Acids; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; Phenylacetates	2015
Free Levels of Selected Organic Solutes and Cardiovascular Morbidity and Mortality in Hemodialysis Patients: Results from the Retained Organic Solutes and Clinical Outcomes (ROSCO) Investigators. PloS one, 2015, Volume: 10, Issue:5 Topics: Adult; Aged; Biomarkers; Cardiovascular Diseases; Cause of Death; Cresols; Female; Glutamine; Hippurates; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Morbidity; Mortality; Patient Outcome Assessment; Renal Dialysis; Sulfuric Acid Esters; United States	2015
Exploring Protein Binding of Uremic Toxins in Patients with Different Stages of Chronic Kidney Disease and during Hemodialysis. Toxins, 2015, Sep-28, Volume: 7, Issue:10 Topics: Aged; Aged, 80 and over; Cresols; Cross-Sectional Studies; Female; Glucuronides; Hippurates; Humans; Indican; Indoleacetic Acids; Male; Middle Aged; Protein Binding; Renal Dialysis; Renal Insufficiency, Chronic; Serum Albumin; Severity of Illness Index; Sulfuric Acid Esters; Uremia	2015
Metabolomics Study of Roux-en-Y Gastric Bypass Surgery (RYGB) to Treat Type 2 Diabetes Patients Based on Ultraperformance Liquid Chromatography-Mass Spectrometry. Journal of proteome research, 2016, Apr-01, Volume: 15, Issue:4 Topics: Adult; Amino Acids; Bile Acids and Salts; Bilirubin; Biomarkers; Carnitine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Energy Metabolism; Fatty Acids, Nonesterified; Female; Gastric Bypass; Hippurates; Humans; Indican; Insulin Resistance; Male; Mass Spectrometry; Metabolomics; Middle Aged; Obesity, Morbid; Oxidative Stress; Prognosis; Remission Induction; Treatment Outcome; Tryptophan; Weight Loss	2016
Simultaneous Determination of Five Specific and Sensitive Nephrotoxicity Biomarkers in Serum and Urine Samples of Four Drug-Induced Kidney Injury Models. Journal of chromatographic science, 2017, Volume: 55, Issue:1 Topics: Acute Kidney Injury; Animals; Biomarkers; Creatinine; Glycine; Hippurates; Indican; Kidney; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; ROC Curve; Sensitivity and Specificity; Uric Acid	2017
Diurnal and Long-term Variation in Plasma Concentrations and Renal Clearances of Circulating Markers of Kidney Proximal Tubular Secretion. Clinical chemistry, 2017, Volume: 63, Issue:4 Topics: Adult; Biomarkers; Chromatography, Liquid; Cresols; Female; Glycine; Hippurates; Humans; Indican; Kidney Tubules, Proximal; Male; Sulfuric Acid Esters; Tandem Mass Spectrometry	2017
Gut microbiome-related metabolic changes in plasma of antibiotic-treated rats. Archives of toxicology, 2017, Volume: 91, Issue:10 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Blood; Body Weight; Eating; Fluoroquinolones; Gastrointestinal Microbiome; Glycerol; Hippurates; Indican; Indoleacetic Acids; Metabolome; Metabolomics; Rats, Wistar; Tetracyclines	2017
Exploring binding characteristics and the related competition of different protein-bound uremic toxins. Biochimie, 2017, Volume: 139 Topics: Binding, Competitive; Case-Control Studies; Chromatography, High Pressure Liquid; Cresols; Hippurates; Humans; Indican; Indoleacetic Acids; Protein Binding; Protein Processing, Post-Translational; Renal Dialysis; Renal Insufficiency, Chronic; Serum Albumin; Sulfuric Acid Esters; Tandem Mass Spectrometry; Toxins, Biological; Uremia	2017
Spontaneous variability of pre-dialysis concentrations of uremic toxins over time in stable hemodialysis patients. PloS one, 2017, Volume: 12, Issue:10 Topics: Aged; Aged, 80 and over; Analysis of Variance; Arginine; beta 2-Microglobulin; Creatinine; Female; Hemodialysis Solutions; Hippurates; Humans; Indican; Male; Middle Aged; Observer Variation; Phosphorus; Renal Dialysis; Renal Insufficiency, Chronic; Toxins, Biological; Urea; Uric Acid	2017
Carbon Adsorbents With Dual Porosity for Efficient Removal of Uremic Toxins and Cytokines from Human Plasma. Scientific reports, 2017, 11-02, Volume: 7, Issue:1 Topics: Adsorption; beta 2-Microglobulin; Carbon; Cytokines; Hippurates; Humans; Indican; Porosity; Sorption Detoxification; Toxins, Biological; Uremia	2017
Increasing the removal of protein-bound uremic toxins by liposome-supported hemodialysis. Artificial organs, 2019, Volume: 43, Issue:5 Topics: Animals; Cresols; Dialysis Solutions; Equipment Design; Hippurates; Indican; Kidney Failure, Chronic; Liposomes; Male; Rats, Sprague-Dawley; Renal Dialysis; Sulfuric Acid Esters; Toxins, Biological; Uremia	2019
Association between Protein-Bound Uremic Toxins and Asymptomatic Cardiac Dysfunction in Patients with Chronic Kidney Disease. Toxins, 2018, 12-05, Volume: 10, Issue:12 Topics: Adult; Arterial Pressure; Cardiac Output; Cresols; Exercise; Glucuronides; Heart Diseases; Heart Rate; Hippurates; Humans; Indican; Indoleacetic Acids; Male; Middle Aged; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Toxins, Biological; Uremia	2018
Selective Transport of Protein-Bound Uremic Toxins in Erythrocytes. Toxins, 2019, 07-01, Volume: 11, Issue:7 Topics: Biological Transport; Cresols; Erythrocytes; Hippurates; Humans; Indican; Indoleacetic Acids; Protein Binding; Renal Dialysis; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Uremia	2019
Development and validation of a UHPLC-MS/MS method for measurement of a gut-derived uremic toxin panel in human serum: An application in patients with kidney disease. Journal of pharmaceutical and biomedical analysis, 2019, Sep-10, Volume: 174 Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cresols; Hippurates; Humans; Hydrogen-Ion Concentration; Indican; Kidney Diseases; Kynurenic Acid; Quality Control; Reproducibility of Results; Risk Factors; Solvents; Sulfuric Acid Esters; Tandem Mass Spectrometry; Time Factors; Uremia	2019
Carbon Nanotube/Conducting Polymer Hybrid Nanofibers as Novel Organic Bioelectronic Interfaces for Efficient Removal of Protein-Bound Uremic Toxins. ACS applied materials & interfaces, 2019, Nov-27, Volume: 11, Issue:47 Topics: Adsorption; Cresols; Electronics; Hippurates; Humans; Indican; Nanotubes, Carbon; Polymers; Proteins; Renal Dialysis; Toxins, Biological; Uremia	2019
Two rapid, accurate liquid chromatography tandem mass spectrometry methods for the quantification of seven uremic toxins: An application for describing their accumulation kinetic profile in a context of acute kidney injury. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Sep-01, Volume: 1152 Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Biomarkers; Chromatography, Liquid; Cresols; Female; Furans; Hippurates; Humans; Indican; Limit of Detection; Linear Models; Male; Middle Aged; Propionates; Reproducibility of Results; Tandem Mass Spectrometry	2020
Associations among total p-cresylsulfate, indoxyl sulfate and hippuric acid levels with hemodialysis quality indicators in maintenance hemodialysis patients. Clinica chimica acta; international journal of clinical chemistry, 2021, Volume: 516 Topics: Cresols; Hippurates; Humans; Indican; Quality Indicators, Health Care; Renal Dialysis; Sulfuric Acid Esters; Uremia	2021
Impaired Tubular Secretion of Organic Solutes in Advanced Chronic Kidney Disease. Journal of the American Society of Nephrology : JASN, 2021, Volume: 32, Issue:11 Topics: Adult; Aged; Creatinine; Cresols; Female; Glomerular Filtration Rate; Glutamine; Hippurates; Humans; Indican; Kidney Tubules; Male; Metabolomics; Middle Aged; Renal Insufficiency, Chronic; Solubility; Uremic Toxins	2021
Correlation between Saliva Levels and Serum Levels of Free Uremic Toxins in Healthy Volunteers. Toxins, 2023, 02-13, Volume: 15, Issue:2 Topics: Chromatography, Liquid; Healthy Volunteers; Humans; Indican; Renal Dialysis; Saliva; Sulfates; Tandem Mass Spectrometry; Toxins, Biological; Tyrosine; Uremia; Uremic Toxins	2023
Quantitative, Targeted Analysis of Gut Microbiota Derived Metabolites Provides Novel Biomarkers of Early Diabetic Kidney Disease in Type 2 Diabetes Mellitus Patients. Biomolecules, 2023, 07-07, Volume: 13, Issue:7 Topics: Arginine; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Gastrointestinal Microbiome; Humans; Indican; Metabolomics; Sulfates	2023
Association between Dental Scores and Saliva Uremic Toxins. Toxins, 2023, Nov-20, Volume: 15, Issue:11 Topics: Chromatography, Liquid; Humans; Indican; Prospective Studies; Renal Insufficiency, Chronic; Saliva; Tandem Mass Spectrometry; Toxins, Biological; Uremia; Uremic Toxins	2023