hippolachnin-a and dithiane

hippolachnin-a has been researched along with dithiane* in 1 studies

Other Studies

1 other study(ies) available for hippolachnin-a and dithiane

Article	Year
Total Synthesis of the Antitumor Antibiotic Basidalin. The Journal of organic chemistry, 2016, 08-05, Volume: 81, Issue:15 The first synthesis of the tetronamide antibiotic basidalin was accomplished in five steps and 39% overall yield from readily available 4-bromo-2-triisopropylsilyloxyfuran and 2-formyl-1,3-dithiane. Highlights include: (i) regio- and stereocontrolled assemblage of a pivotal (Z)-γ-ylidene-β-bromobutenolide intermediate by stereodirected vinylogous aldol condensation (SVAC), (ii) installation of the amino group via aza-Michael addition/elimination, and crucially (iii) facile access to basidalin by late-stage dithiane removal. Topics: Aldehydes; Antibiotics, Antineoplastic; Furans; Magnetic Resonance Spectroscopy; Molecular Structure; Polyketides; Quinolizines; Stereoisomerism; Sulfur Compounds	2016

Article

Year

Total Synthesis of the Antitumor Antibiotic Basidalin.

The Journal of organic chemistry, 2016, 08-05, Volume: 81, Issue:15

The first synthesis of the tetronamide antibiotic basidalin was accomplished in five steps and 39% overall yield from readily available 4-bromo-2-triisopropylsilyloxyfuran and 2-formyl-1,3-dithiane. Highlights include: (i) regio- and stereocontrolled assemblage of a pivotal (Z)-γ-ylidene-β-bromobutenolide intermediate by stereodirected vinylogous aldol condensation (SVAC), (ii) installation of the amino group via aza-Michael addition/elimination, and crucially (iii) facile access to basidalin by late-stage dithiane removal.

Topics: Aldehydes; Antibiotics, Antineoplastic; Furans; Magnetic Resonance Spectroscopy; Molecular Structure; Polyketides; Quinolizines; Stereoisomerism; Sulfur Compounds

2016