Compounds > higenamine
Page last updated: 2024-09-02

higenamine and isoproterenol

higenamine has been researched along with isoproterenol in 10 studies

Compound Research Comparison

Studies
(higenamine)		Trials
(higenamine)		Recent Studies (post-2010)
(higenamine)		Studies
(isoproterenol)		Trials
(isoproterenol)		Recent Studies (post-2010) (isoproterenol)
13647030,7808032,640

Protein Interaction Comparison

ProteinTaxonomyhigenamine (IC50)isoproterenol (IC50)
Beta-2 adrenergic receptorHomo sapiens (human)0.246
Beta-1 adrenergic receptorHomo sapiens (human)0.333
Beta-2 adrenergic receptorRattus norvegicus (Norway rat)0.2125
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)1.77
Beta-1 adrenergic receptorRattus norvegicus (Norway rat)0.2125
Beta-3 adrenergic receptorRattus norvegicus (Norway rat)0.2125
Beta-2 adrenergic receptorCanis lupus familiaris (dog)0.6667

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Feng, YP; Gao, H; Zeng, GY1
Liu, WH; Zeng, GY; Zhou, YP1
Feng, YP; Zeng, GY1
Feng, YP; Jia, HJ; Zeng, GY; Zhang, LY1
Han, HW; Sun, FL; Wang, JZ1
Feng, YP; Zeng, GY; Zhan, HS; Zhang, Y1
Liu, XJ; Tao, S; Wagner, HN1
Chen, ZZ; Li, QA; Liu, L; Wang, HX; Zhou, TJ1
Islam, MA; Kimura, I; Kimura, M1
Ling, W; Wu, MP; Xue, C; Yan, C; Zhang, YS; Zhou, Z; Zhu, JX1

Other Studies

10 other study(ies) available for higenamine and isoproterenol

ArticleYear
[Effect of higenamine on alpha-adrenoceptors].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:3

    Topics: Adrenergic beta-Antagonists; Alkaloids; Animals; Female; Isoproterenol; Male; Muscle Contraction; Rats; Receptors, Adrenergic, alpha; Tetrahydroisoquinolines

1986
[Effects of DL-demethylcoclaurine on experimental heart failure].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1988, Volume: 23, Issue:2

    Topics: Adrenergic beta-Agonists; Alkaloids; Animals; Cardiotonic Agents; Female; Guinea Pigs; Heart Failure; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Tetrahydroisoquinolines

1988
Effect of dl-demethylcoclaurine on alpha and beta-adrenergic receptors.
    Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, 1988, Volume: 3, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Alkaloids; Animals; Cerebral Cortex; Erythrocyte Membrane; Isoproterenol; Male; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tetrahydroisoquinolines; Turkeys; Vas Deferens

1988
[Effects of dl-demethyl coclaurine on beta-adrenergic receptors and adenylate cyclase in turkey erythrocyte membrane].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1982, Volume: 17, Issue:9

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Alkaloids; Animals; Erythrocyte Membrane; Erythrocytes; In Vitro Techniques; Isoproterenol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetrahydroisoquinolines; Turkeys

1982
[Effect of dl-demethylcoclaurine on cultured rat heart cells (author's transl)].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1981, Volume: 2, Issue:2

    Topics: Alkaloids; Animals; Cardiotonic Agents; Cells, Cultured; Female; Heart; Heart Rate; Isoproterenol; Male; Myocardial Contraction; Rats; Receptors, Adrenergic, beta; Tetrahydroisoquinolines

1981
[Effect of dl-demethylcoclaurine on plasma cAMP in mice (author's transl)].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1981, Volume: 2, Issue:2

    Topics: Alkaloids; Animals; Cardiotonic Agents; Cyclic AMP; Dose-Response Relationship, Drug; Isoproterenol; Mice; Receptors, Adrenergic, alpha; Tetrahydroisoquinolines

1981
Measurement of effects of the Chinese herbal medicine higenamine on left ventricular function using a cardiac probe.
    European journal of nuclear medicine, 1983, Volume: 8, Issue:6

    Topics: Adult; Alkaloids; Cardiac Output; Dose-Response Relationship, Drug; Female; Heart Diseases; Heart Rate; Humans; Infusions, Parenteral; Isoproterenol; Male; Middle Aged; Stroke Volume; Tetrahydroisoquinolines

1983
[Effect of Asarum heterotropoides on the left ventricular function of dogs (author's transl)].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1981, Volume: 16, Issue:10

    Topics: Alkaloids; Animals; China; Dogs; Heart; Isoproterenol; Plants, Medicinal; Tetrahydroisoquinolines

1981
Cholera toxin accentuates the antagonism by acetylcholine of higenamine-induced positive chronotropy is isolated right atria of mice.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:11

    Topics: Acetylcholine; Alkaloids; Animals; Cardiotonic Agents; Cholera Toxin; Colforsin; Dobutamine; Drug Synergism; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Mice; Mice, Inbred Strains; Pertussis Toxin; Stimulation, Chemical; Tetrahydroisoquinolines; Virulence Factors, Bordetella

1995
Higenamine attenuates cardiac fibroblast abstract and fibrosis via inhibition of TGF-β1/Smad signaling.
    European journal of pharmacology, 2021, Jun-05, Volume: 900

    Topics: Actins; Adrenergic beta-Agonists; Alkaloids; Animals; Aorta; Apoptosis; Cardiomegaly; Fibrinolytic Agents; Fibroblasts; Fibrosis; Heart Diseases; Hypertension; Isoproterenol; Mice; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Tetrahydroisoquinolines; Transforming Growth Factor beta1

2021