hexobarbital has been researched along with warfarin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (59.09) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Caron, G; Ermondi, G | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Conney, AH; Kapitulnik, J; Popper, PJ | 1 |
| Buening, MK; Conney, AH; Fortner, JG; Kapitulnik, J; Poppers, PJ | 1 |
| Conney, AH; Hsiao, KC; Kuntzman, R; Loub, WD; Pantuck, EJ; Wattenberg, LW | 1 |
| Herczeg, T; Mathur, PP; Reavey-Cantwell, NH; Smyth, RD | 1 |
| Lush, IE | 1 |
| Gibaldi, M | 1 |
| Apseloff, G; Gerber, N; Hilliard, JB; Mays, DC | 1 |
| Conney, AH; Kappas, A | 1 |
| Cooper, SD; De la Iglesia, FA; Feuer, G; Lumb, G | 1 |
| Jenner, P; Testa, B | 1 |
| Feuer, G; Granda, V | 1 |
| Baesl, TJ; Mallov, S | 1 |
| Feuer, G; Lumb, G; Moddel, G; Sosa-Lucero, JC | 1 |
| Azarnoff, DL; Mustala, OO | 1 |
| Lee, CK; Shin, KH; Woo, WS | 1 |
| Farghali, H; Hynie, S; Kren, V; Mráz, M | 1 |
| Maftouh, M; Mangelings, D; Massart, DL; Matthijs, N; Tanret, I; Vander Heyden, Y | 1 |
3 review(s) available for hexobarbital and warfarin
| Article | Year |
|---|---|
Drug interactions: Part I.
Topics: Antidepressive Agents, Tricyclic; Caffeine; Cimetidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Fluconazole; Fluoxetine; Hexobarbital; Humans; Ketoconazole; Nimodipine; Oxidoreductases; Pharmaceutical Preparations; Rifampin; Stereoisomerism; Warfarin; Zidovudine | 1992 |
Interindividual differences in the metabolism of xenobiotics.
Topics: Aflatoxin B1; Aflatoxins; Antipyrine; Benzopyrenes; Biotransformation; Carcinogens; Coumarins; Desipramine; Diet; Dihydroxydihydrobenzopyrenes; Hexobarbital; Humans; Liver; Microsomes, Liver; Pharmaceutical Preparations; Smoking; Steroids; Zoxazolamine | 1985 |
The influence of stereochemical factors on drug disposition.
Topics: Alcohols; Amphetamine; Analgesics; Animals; Barbiturates; Dealkylation; Deamination; Dextroamphetamine; Dihydroxyphenylalanine; Ephedrine; Guinea Pigs; Haplorhini; Hexobarbital; Humans; Hydantoins; Hydroxylation; Ketones; Male; Methamphetamine; Mice; Oxidation-Reduction; Pharmaceutical Preparations; Rabbits; Rats; Species Specificity; Stereoisomerism; Structure-Activity Relationship; Succinimides; Warfarin | 1973 |
19 other study(ies) available for hexobarbital and warfarin
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Comparative metabolism of benzo[a]pyrene and drugs in human liver.
Topics: Adolescent; Adult; Aged; Antipyrine; Benzopyrene Hydroxylase; Benzopyrenes; Coumarins; Female; Hexobarbital; Humans; In Vitro Techniques; Liver; Male; Middle Aged; Mixed Function Oxygenases; Oxidoreductases; Pharmaceutical Preparations; Zoxazolamine | 1977 |
Activation of monooxygenases in human liver by 7,8-benzoflavone.
Topics: Adolescent; Adult; Antipyrine; Autopsy; Benzopyrenes; Biopsy; Coumarins; Dealkylation; Enzyme Activation; Female; Flavonoids; Hexobarbital; Humans; Hydroxylation; In Vitro Techniques; Liver; Male; Microsomes, Liver; Middle Aged; Oxygenases; Zoxazolamine | 1977 |
Stimulatory effect of vegetables on intestinal drug metabolism in the rat.
Topics: Animals; Benzopyrene Hydroxylase; Coumarins; Diet; Enzyme Induction; Hexobarbital; Indoles; Intestinal Mucosa; Intestines; Male; Mixed Function Oxygenases; Oxidoreductases; Pharmaceutical Preparations; Phenacetin; Rats; Vegetables | 1976 |
Induction of hepatic enzymes by methaqualone and effect on warfarin-induced hypoprothrombinemia.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Enzyme Induction; Hexobarbital; Hypoprothrombinemias; Liver; Male; Methaqualone; Phenobarbital; Proadifen; Prothrombin Time; Rats; Sleep; Time Factors; Warfarin | 1976 |
A survey of the response of different strains of mice to substances metabolised by microsomal oxidation; hexobarbitone, zoxazolamine and warfarin.
Topics: Animals; Female; Hexobarbital; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Paralysis; Sex Factors; Sleep; Species Specificity; Warfarin; Zoxazolamine | 1976 |
Inhibition and induction of drug metabolism by psoralens: alterations in duration of sleep induced by hexobarbital and in clearance of caffeine and hexobarbital in mice.
Topics: Animals; Caffeine; Coumarins; Furocoumarins; Half-Life; Hexobarbital; Male; Methoxsalen; Mice; Sleep; Time Factors; Warfarin | 1991 |
Microsomal phospholipids and drug action--quantitative biochemical and electron microscopic studies.
Topics: Animals; Carbon Tetrachloride; Choline; Coumarins; Dactinomycin; Endoplasmic Reticulum; Ethanol; Ethionine; Female; Glucose-6-Phosphatase; Hexobarbital; Histocytochemistry; In Vitro Techniques; Male; Methylcholanthrene; Microscopy, Electron; Microsomes, Liver; Nitrosamines; Phenobarbital; Phosphatidylethanolamines; Phospholipases; Phospholipids; Rats | 1972 |
Antagonistic effect of foreign compounds on microsomal enzymes of the liver of the rat.
Topics: Acetates; Amides; Animals; Carbon Tetrachloride; Coumarins; Drug Antagonism; Enzymes; Ethionine; Female; Hexobarbital; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Phosphoric Monoester Hydrolases; Rats; Toluene | 1970 |
Effect of ethanol on rates of elimination and metabolism of zoxazolamine, hexobarbital and warfarin sodium in the rat.
Topics: Animals; Ethanol; Glucose; Hexobarbital; Kinetics; Liver; Male; Microsomes, Liver; Proteins; Rats; Time Factors; Trichloroacetic Acid; Warfarin; Zoxazolamine | 1972 |
Failure of various drugs to induce drug-metabolizing enzymes in extrahepatic tissues of the rat.
Topics: Adrenal Glands; Aminopyrine; Aniline Compounds; Animals; Brain; Chlorpromazine; Coumarins; Enzyme Induction; Female; Hexobarbital; Hydrochlorothiazide; Intestines; Kidney; Liver; Male; Methylcholanthrene; Metyrapone; Mixed Function Oxygenases; Organ Size; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors | 1971 |
Effect of oxygen tension on drug levels and pharmacological action in the intact animal.
Topics: Animals; Barbiturates; Brain Chemistry; Hexobarbital; Hyperbaric Oxygenation; Hypoxia; Isoniazid; Male; Phenylbutazone; Propiophenones; Rats; Sulfadiazine; Warfarin; Zoxazolamine | 1969 |
Effect of naturally occurring coumarins on the activity of drug metabolizing enzymes.
Topics: Animals; Coumarins; Hexobarbital; Liver; Male; Mice; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Rats; Rats, Inbred Strains; Sleep; Structure-Activity Relationship | 1983 |
Phase I and phase II xenobiotic biotransformation in different inbred strains of rats: study in immobilized perfused hepatocytes.
Topics: Animals; Biotransformation; Cells, Immobilized; Coumarins; Dinitrochlorobenzene; Drug Resistance; Hexobarbital; In Vitro Techniques; Isoproterenol; Liver; Male; Nitrophenols; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Wistar; Species Specificity; Xenobiotics | 1998 |
Separation strategy for acidic chiral pharmaceuticals with capillary electrochromatography on polysaccharide stationary phases.
Topics: Acetonitriles; Buffers; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Flurbiprofen; Hexobarbital; Hydrogen-Ion Concentration; Ibuprofen; Pharmaceutical Preparations; Polysaccharides; Stereoisomerism; Temperature; Warfarin | 2005 |