hexobarbital and rifampin

hexobarbital has been researched along with rifampin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19908 (57.14)18.7374
1990's3 (21.43)18.2507
2000's2 (14.29)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Breimer, DD; Richter, E; Zilly, W4
Breimer, DD; Buchenau, D; Richter, E; Wernze, H; Zilly, W1
Mazel, P; Pessayre, D1
Gibaldi, M1
Blouin, RA; Chandler, MH; Shedlofsky, SI; Smith, DA; Wedlund, PJ1
Hatano, M; Ishihara, M; Katsu, K1
Mitcheva, M; Staneva-Stoytcheva, D1
Belpaire, FM; De Rick, A; Rosseel, MT1

Reviews

1 review(s) available for hexobarbital and rifampin

ArticleYear
Drug interactions: Part I.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:5

    Topics: Antidepressive Agents, Tricyclic; Caffeine; Cimetidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Fluconazole; Fluoxetine; Hexobarbital; Humans; Ketoconazole; Nimodipine; Oxidoreductases; Pharmaceutical Preparations; Rifampin; Stereoisomerism; Warfarin; Zidovudine

1992

Other Studies

13 other study(ies) available for hexobarbital and rifampin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Influence of rifampicin on drug metabolism: differences between hexobarbital and antipyrine.
    Clinical pharmacology and therapeutics, 1977, Volume: 21, Issue:4

    Topics: Adult; Antipyrine; Galactose; Half-Life; Hexobarbital; Humans; Indocyanine Green; Male; Metabolic Clearance Rate; Rifampin

1977
Stimulation of drug metabolism by rifampicin in patients with cirrhosis or cholestasis measured by increased hexobarbital and tolbutamide clearance.
    European journal of clinical pharmacology, 1977, Apr-20, Volume: 11, Issue:4

    Topics: Adult; Aged; Cholestasis; Female; Hexobarbital; Humans; Kinetics; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged; Rifampin; Stimulation, Chemical; Time Factors; Tolbutamide

1977
[Influence of rifampicin on the metabolic clearance of galactose and antipyrine as compared with hexobarbital].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1975, Volume: 81

    Topics: Adult; Antipyrine; Galactose; Hexobarbital; Humans; Liver; Metabolic Clearance Rate; Rifampin; Stimulation, Chemical

1975
Induction of drug metabolism in man after rifampicin treatment measured by increased hexobarbital and tolbutamide clearance.
    European journal of clinical pharmacology, 1975, Dec-19, Volume: 9, Issue:2-3

    Topics: Adult; Creatine; Half-Life; Hexobarbital; Humans; Kinetics; Liver Function Tests; Male; Metabolic Clearance Rate; Models, Biological; Rifampin; Tolbutamide

1975
Induction and inhibition of hepatic drug metabolizing enzymes by rifampin.
    Biochemical pharmacology, 1976, Apr-15, Volume: 25, Issue:8

    Topics: Aniline Compounds; Animals; Benzopyrenes; Enzyme Induction; Estradiol; Hexobarbital; Liver; Male; Mice; Mice, Inbred ICR; Morphinans; Nitrophenols; Rifampin; Time Factors; Zoxazolamine

1976
Age-dependent stereoselective increase in the oral clearance of hexobarbitone isomers caused by rifampicin.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:6

    Topics: Administration, Oral; Adult; Aged; Aging; Chromatography, High Pressure Liquid; Drug Interactions; Hexobarbital; Humans; Male; Metabolic Clearance Rate; Rifampin; Stereoisomerism

1991
Examination of toxicity of diisopropylammonium dichloracetate (DADA), remedies for cardiac diseases, toward isolated rat hepatocytes.
    Meikai Daigaku shigaku zasshi = The Journal of Meikai University School of Dentistry, 1990, Volume: 19, Issue:1

    Topics: Animals; Calcium Gluconate; Cell Survival; Cells, Cultured; Drug Combinations; Felypressin; Hexobarbital; Liver; Male; N-substituted Glycines; Oxygen Consumption; Prilocaine; Propylamines; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Rifampin; Thiopental; Trapidil; Vitamin B Complex

1990
Influence of the combined chemotherapeutic drug tuboprim on drug metabolism.
    Acta physiologica et pharmacologica Bulgarica, 1988, Volume: 14, Issue:1

    Topics: Animals; Drug Combinations; Hexobarbital; Male; Mice; Mice, Inbred Strains; Mixed Function Oxygenases; Pharmaceutical Preparations; Rats; Rats, Inbred Strains; Rifampin; Sleep; Trimethoprim

1988
Enhanced plasma binding of propranolol and oxprenolol and induction of hexobarbital and antipyrine metabolism by rifampicin treatment in the dog.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 259, Issue:2

    Topics: Animals; Antipyrine; Blood Proteins; Dogs; Female; Half-Life; Hexobarbital; Male; Oxprenolol; Propranolol; Protein Binding; Rifampin

1982
Disposition of hexobarbital in intra- and extrahepatic cholestasis in man and the influence of drug metabolism-inducing agents.
    European journal of clinical pharmacology, 1980, Volume: 17, Issue:3

    Topics: Adult; Aged; Cholestasis, Extrahepatic; Cholestasis, Intrahepatic; Enzyme Induction; Female; Hexobarbital; Humans; Inactivation, Metabolic; Kinetics; Liver; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Phenytoin; Rifampin

1980