hexobarbital and promethazine

hexobarbital has been researched along with promethazine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Borchert, HH; Pfeifer, S; Szołomicka-Orfinger, I1
Herr, F; Voith, K1
Borchert, HH; Pfeifer, S; Schulz, H; Schuster, S1
BEGUIN, M; FLEURY, C; FROMMEL, E; VON LEDEBUR, I1
HAPKE, HJ1
RIDING, JE1
BALINT, G1

Other Studies

11 other study(ies) available for hexobarbital and promethazine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Metabolic drug interactions of 9,9-dioxopromethazine (prothanon)].
    Die Pharmazie, 1978, Volume: 33, Issue:10

    Topics: Animals; Cyclic S-Oxides; Drug Interactions; Female; Hexobarbital; In Vitro Techniques; Liver; Promethazine; Rats

1978
Psychopharmacological evaluation of a new antidepressant: butriptyline.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:2

    Topics: Acetylcholine; Amphetamine; Animals; Antidepressive Agents; Atropine; Body Temperature; Consummatory Behavior; Depression, Chemical; Dibenzocycloheptenes; Drug Antagonism; Drug Synergism; Escape Reaction; Ethanol; Guinea Pigs; Hexobarbital; Histamine; Ileum; Imipramine; Male; Mice; Promethazine; Rats; Reserpine; Tremorine

1969
[Metabolic interactions of promethazine (author's transl)].
    Die Pharmazie, 1981, Volume: 36, Issue:12

    Topics: Animals; Cytochrome P-450 Enzyme System; Female; Glucuronosyltransferase; Hexobarbital; Liver; Metabolism; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Organ Size; Promethazine; Rats; Rats, Inbred Strains; Sleep; Time Factors

1981
[Deviations in the pharmacodynamic action of various drugs by hypo- and hyperthermia. 2].
    Helvetica physiologica et pharmacologica acta, 1962, Volume: Suppl 12

    Topics: Acetylcholine; Aminobutyrates; Amphetamine; Amphetamines; Atropine; Chlordiazepoxide; Chlorpromazine; Cocaine; Convulsive Therapy; Electroconvulsive Therapy; Fever; Hexobarbital; Histamine; Hypothermia; Hypothermia, Induced; Lidocaine; Lobeline; Morphine; Papaverine; Phenobarbital; Promethazine; Thiopental

1962
[Effect of narcotics, analeptics, secale preparations and phenothiazine derivatives on the vagal respiratory and circulatory reflexes in the rat and guinea pig].
    Medicina experimentalis : International journal of experimental medicine, 1962, Volume: 7

    Topics: Animals; Bemegride; Blood Circulation; Central Nervous System Stimulants; Chloralose; Chlorpromazine; Ergot Alkaloids; Guinea Pigs; Hexobarbital; Morphine; Narcotics; Pentobarbital; Pentylenetetrazole; Promazine; Promethazine; Rats; Reflex; Respiration; Secale; Thiopental; Vagus Nerve

1962
METHOHEXITAL.
    International anesthesiology clinics, 1964, Volume: 2

    Topics: Anesthesia; Anesthesia, Intravenous; Anesthesiology; Atropine; Hexobarbital; Humans; Meperidine; Methohexital; Pharmacology; Preanesthetic Medication; Promethazine; Scopolamine; Thiopental

1964
EXPERIMENTAL COMPARISON OF THE ANAESTHESIA POTENTIATING EFFECT OF HYDERGIN AND SOME PHENOTHIAZINE DERIVATIVES.
    Acta physiologica Academiae Scientiarum Hungaricae, 1964, Volume: 25

    Topics: Acepromazine; Anesthesia; Chlorpromazine; Dihydroergotoxine; Ergot Alkaloids; Hexobarbital; Hibernation; Hypothermia, Induced; Mice; Parasympatholytics; Pharmacology; Phenothiazines; Prochlorperazine; Promethazine; Research; Tranquilizing Agents

1964