hexobarbital and probenecid

hexobarbital has been researched along with probenecid in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Wahlström, G1
Bolander, HG; Wahlström, G1
Lyness, WH; Mycek, MJ1
BURNS, JJ1

Reviews

1 review(s) available for hexobarbital and probenecid

ArticleYear
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY.
    The American journal of medicine, 1964, Volume: 37

    Topics: Animals; Benzopyrenes; Cyclizine; Dicumarol; Diphenhydramine; Dogs; Drug Therapy; Enzyme Induction; Enzymes; Glutethimide; Hexobarbital; Liver; Meprobamate; Metabolism; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Probenecid; Rats; Research; Tolbutamide; Toxicology; Zoxazolamine

1964

Other Studies

7 other study(ies) available for hexobarbital and probenecid

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Increased penetration of barbital through the bloodbrain barrier in the rat after pretreatment with probenecid.
    Acta pharmacologica et toxicologica, 1978, Volume: 43, Issue:4

    Topics: Anesthesia; Animals; Barbital; Barbiturates; Biological Transport, Active; Blood-Brain Barrier; Brain; Hexobarbital; Infusions, Parenteral; Injections, Intraperitoneal; Male; Probenecid; Rats; Time Factors

1978
Interaction between probenecid and two lipid-soluble barbiturates in the rat.
    Neuropharmacology, 1984, Volume: 23, Issue:8

    Topics: Animals; Barbiturates; Brain Chemistry; Drug Interactions; Electroencephalography; Hexobarbital; Male; Probenecid; Rats; Rats, Inbred Strains; Thiopental; Tissue Distribution

1984
Potentiation of barbiturate hypnosis by probenecid: differential effect in tolerant animals.
    Neuropharmacology, 1981, Volume: 20, Issue:3

    Topics: Animals; Barbiturates; Brain; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Hexobarbital; Injections, Intraventricular; Liver; Male; Motor Activity; Phenobarbital; Probenecid; Rats; Reflex

1981