hexobarbital and phenacetin

hexobarbital has been researched along with phenacetin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199010 (83.33)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Conney, AH; Hsiao, KC; Kuntzman, R; Loub, WD; Pantuck, EJ; Wattenberg, LW1
Jablońska, JK; Piotrowski, JK; Wiśniewska-Knypl, JM1
Orrenius, S; Schenkman, JB; von Bahr, C; Wilson, BJ1
Kato, R; Onoda, K; Takayanagi, M1
Kaltiala, EH; Kärki, NT; Larmi, TK; Pelkonen, O1
McEwen, J; Stevenson, IH1
Bacci, MC; Bianchi, C; Bonardi, G; Coppi, G; Molino, C; Tomasi, L; Vidi, A1
Hiskey, CF; Lachman, L; Mayell, JS1
Cinti, DL; Kraschnitz, R; Moldeus, P; Orrenius, S; Schenkman, JB1
Orrenius, S; Schenkman, JB; Von Bahr, C; Wilson, B1

Reviews

2 review(s) available for hexobarbital and phenacetin

ArticleYear
On the significance of drug-induced spectral changes in liver microsomes.
    Biochemical Society symposium, 1972, Volume: 34

    Topics: Alkaloids; Amphetamine; Aniline Compounds; Animals; Binding Sites; Cytochrome P-450 Enzyme System; Desipramine; Hexobarbital; Hydroxylation; Microsomes, Liver; NADP; Nortriptyline; Oxidoreductases; Phenacetin; Rats; Spectrum Analysis; Testosterone; Tryptophan

1972
Drug metabolism.
    Scottish medical journal, 1972, Volume: 17, Issue:2

    Topics: Adult; Aged; Alcohol Oxidoreductases; Animals; Antipyrine; Dogs; Enzyme Induction; Enzyme Inhibitors; Enzymes; Female; Half-Life; Hexobarbital; Humans; Liver; Liver Diseases; Male; Mice; Middle Aged; Pharmaceutical Preparations; Phenacetin; Rabbits; Rats; Species Specificity

1972

Other Studies

10 other study(ies) available for hexobarbital and phenacetin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Stimulatory effect of vegetables on intestinal drug metabolism in the rat.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 198, Issue:2

    Topics: Animals; Benzopyrene Hydroxylase; Coumarins; Diet; Enzyme Induction; Hexobarbital; Indoles; Intestinal Mucosa; Intestines; Male; Mixed Function Oxygenases; Oxidoreductases; Pharmaceutical Preparations; Phenacetin; Rats; Vegetables

1976
Effect of repeated exposure to aniline, nitrobenzene, and benzene on liver microsomal metabolism in the rat.
    British journal of industrial medicine, 1975, Volume: 32, Issue:1

    Topics: Aminopyrine N-Demethylase; Aniline Compounds; Animals; Benzene; Depression, Chemical; Fever; Hexobarbital; Male; Microsomes, Liver; Mixed Function Oxygenases; Nitrobenzenes; Oxidoreductases; Phenacetin; Phenobarbital; Proadifen; Rats; Sleep; Stimulation, Chemical

1975
Species difference in the inhibition of drug metabolism by liver microsomes by different inhibitors.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:3

    Topics: Aminopyrine; Aniline Compounds; Animals; Cocaine; Depression, Chemical; Drug Antagonism; Ethylamines; Hexobarbital; Histamine H1 Antagonists; Kinetics; Male; Meperidine; Mice; Microsomes, Liver; Morphine; Nitrophenols; Oxidation-Reduction; Pentobarbital; Pharmaceutical Preparations; Phenacetin; Phenylhydrazines; Piperazines; Proadifen; Rabbits; Rats; Species Specificity; Zoxazolamine

1969
Cytochrome P-450-linked monooxygenase system and drug-induced spectral interactions in human liver microsomes.
    Chemico-biological interactions, 1974, Volume: 9, Issue:3

    Topics: Amines; Aniline Compounds; Animals; Antimetabolites; Benzene Derivatives; Butanols; Carbon Monoxide; Cholelithiasis; Cyanides; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Guinea Pigs; Hexobarbital; Humans; Liver; Microsomes, Liver; Oxygenases; Phenacetin; Proadifen; Rabbits; Rats; Smoking; Species Specificity; Spectrophotometry

1974
Experimental models for the in vivo evaluation of enzyme induction properties of drugs.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:12

    Topics: Acetanilides; Amides; Aminopyrine; Amphetamine; Aniline Compounds; Animals; Central Nervous System; Codeine; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Hexobarbital; Male; Meperidine; Mice; Oxotremorine; Pentobarbital; Phenacetin; Phenytoin; Rabbits; Rats; Strychnine; Tolbutamide; Tremorine; Zoxazolamine

1973
Quantitative analysis of a multicomponent drug product using liquid chromatography.
    Analytical chemistry, 1974, Volume: 46, Issue:3

    Topics: Analgesics; Aspirin; Caffeine; Chromatography, Gas; Hexobarbital; Phenacetin; Solvents; Temperature

1974
The nature of the reverse type I (modified type II) spectral change in liver microsomes.
    Biochemistry, 1972, Nov-07, Volume: 11, Issue:23

    Topics: Alcohols; Aminopyrine; Aniline Compounds; Animals; Benzopyrenes; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Drug Synergism; Hexobarbital; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Phenacetin; Rabbits; Rats; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet

1972
The significance of drug-induced spectral changes in liver microsomal fraction.
    The Biochemical journal, 1971, Volume: 125, Issue:2

    Topics: Animals; Binding Sites; Cytochromes; Hexobarbital; Methylcholanthrene; Microsomes, Liver; Naphthalenes; Nortriptyline; Oxidoreductases; Phenacetin; Rabbits; Spectrum Analysis

1971