hexobarbital and pentobarbital

hexobarbital has been researched along with pentobarbital in 141 studies

Research

Studies (141)

Timeframe	Studies, this research(%)	All Research%
pre-1990	134 (95.04)	18.7374
1990's	2 (1.42)	18.2507
2000's	4 (2.84)	29.6817
2010's	1 (0.71)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baker, JK; Borne, RF; Rauls, DO	1
Brent, DA; Henry, DW; Minick, DJ; Sabatka, JJ	1
Caron, G; Ermondi, G	1
Lombardo, F; Obach, RS; Waters, NJ	1
Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Dubský, H; Hána, K; Pestálovă, M; Pracharová, M	1
Airall, AA; Jackson, MJ	1
Akashi, Y; Chiba, T; Horiuchi, M	1
Hiller, HH; Merkenschlager, M	1
Lovell, D; Lush, IE	1
Anda, LP; Bantzer, P; Liappis, N	1
Bjertnaes, LJ	1
Adams, HR; Isaacson, EL; Masters, BS	1
Canfield, RE; Kappas, A; Rifkind, AB	1
Turnbull, MJ; Watkins, JW	1
Gizhlarian, MS	1
Endell, W; Seidel, G	1
Dvorchik, BH	1
Formánek, J; Holoubková, E; Plevová, J; Vanícková, M	1
Lal, H; Shan, HC	1
Buchholz, J; Fraser, IM; Strother, A	1
Akaike, N; Oyama, Y; Yakushiji, T	1
Alila, A; Heavner, JE; Rosenberg, PH	1
Jackson, JA; Paul, SM; Schwartz, RD; Skolnick, P; Weigert, D	1
Chang, YF; Feigenbaum, P	1
Devor, DE; Henneman, JR; Lubet, RA; Nims, RW	1
Reinberg, A	1
Dennhardt, R; Gramm, HJ; Heinemeyer, G; Roots, I; Simgen, W	1
Lovell, DP	1
Blumberg, JB; Hayes, KC; Meydani, M	1
Edds, GT; Himes, JA; Shetty, SN	1
Kato, R	3
Cutler, RW; Dudzinski, DS; Markowitz, D	1
Gogolák, G; Liebeswar, G; Stumpf, C	1
Grivel, ML; Ruckebusch, Y	1
Friemel, G; Kurz, H	1
Kurz, H; Mohr, E	1
Absil, J; Buchel, L	2
Bousquet, WF; Driever, CW; Miya, TS	1
Greengard, P; Quinn, GP; Reid, MB	1
Kato, R; Takanaka, A	2
Barnes, DW; Wooles, WR	1
Burke, JC; Furgiuele, AR; High, JP; Horovitz, ZP	1
Daly, MJ; Lightowler, JE; Pickering, RW	1
Burberi, S; Catanese, B; Cioli, V; Silvestrini, B	1
Kato, R; Onoda, K; Takayanagi, M	1
Topham, JC	1
Mandel, HG; Riis, M	1
Peters, MA; Strother, A	1
Ernster, L; Jansson, I; Orrenius, S; Schenkman, JB	1
Gogerty, JH; Iorio, LC; Kerestan, SP; Ryan, EA	1
Edström, A; Larsson, H	1
Gilleran, TG; Lukas, G; Zak, SB	1
Flanagan, RJ; Withers, G	1
Bradley, SG; Munson, AE; Rose, WC	1
Furst, A; Ho, W	1
Faupel, RP; Kampf, SC; Seitz, HJ; Tarnowski, W	1
Jaeger, RJ; Murphy, SD	1
Frumin, MJ; Halevy, S	1
Bacci, MC; Bianchi, C; Bonardi, G; Coppi, G; Molino, C; Tomasi, L; Vidi, A	1
Feller, DR; Lewis, NJ; Witiak, DT	1
Greeley, RH	1
Balacescu, C	1
Gogolák, G; Huck, S; Porges, P; Stumpf, C	1
Dundee, JW	1
Brodeur, J; Lacombe, R	1
Rasmussen, KE; Rasmussen, S; Svendsen, AB	1
Nicoll, RA	1
Hatch, RC	1
Bousquet, WF; Hatfield, GK; Miya, TS	1
Fiereck, EA; Tietz, NW	1
Brown, BR	1
Remmer, H	1
Street, HV	1
Lal, H; Shah, HC	1
Dóda, M; Gellén, B; György, L; Sterk, L	1
Kato, R; Oshima, T; Takayanagi, M	1
Baumel, I; DeFeo, JJ; Lal, H	1
Blackham, A; Spencer, PS	1
Mikikits, W; Mortara, A; Spector, RG	1
Döring, HJ; Olbrisch, RR	2
Feller, DR; Gerald, MC	2
Roberts, P; Turnbull, MJ; Winterburn, A	1
Levine, WG	1
Balazs, T; Dairman, W	1
Gang, H; Lieber, CS; Rubin, E	1
Jarowski, CI; Ward, CO	1
Clark, R; Lynes, TE; Marvel, JP; Price, WA; Smith, DH; Vernier, VG; Woodward, JK	1
Kündig, H	1
Burgison, RM; Dietz, AJ	1
Wahlström, G	1
Delaunois, AL; Marcus, WL; Sperling, F	1
Hadfield, DA; Ramsay, DJ	1
Becker, BA; Harbison, RD	1
Arnold, W; Grützmacher, HF	1
Dickerson, G	1
Chappel, CI; Marton, AV	1
Bousquet, WF; Hoffman, DG; Miya, TS	1
Aboul-Enein, MN; Ahmed, ZF; el-Darawy, ZI; el-Leithy, SA; el-Naga, MA	1
Borzelleca, JF; Wooles, WR	1
McMartin, C; Street, HV	1
Azarnoff, DL; Grady, HJ; Svoboda, DJ	1
Nair, V	1
Chiesara, E; Clementi, F; Conti, F; Meldolesi, J	1
Buchel, L; Tanguy, O	1
Bollkämper, A; Siegers, CP; Younes, M	1
Bainton, CR; Eger, EI; Koblin, DD; Lurz, FW; Nelson, NT; O'Connor, B	1
Gardner, DE; Graham, JA; Illing, JW; Menzel, DB; Miller, FJ	1
Furusawa, S; Sasaki, K; Takayanagi, G	1
Ross, FH; Sermons, AL; Walker, CA	1
Chen, XH; de Zeeuw, RA; Franke, JP; Wijsbeek, J	1
Bhave, SV; Hoffmann, E; Hoffmann, PL; Olsen, RW; Tabakoff, B; Tobin, AJ; Tyndale, RF	1
COMSTOCK, JP; GABOUREL, JD	1
HIRAI, K; KAMO, M; SUZUKI, T; YAMASHITA, K	1
KARAMUSTAFAOGLU, V; LEHMANN, J	1
HAPKE, HJ	1
HINTON, JM	1
CHIESARA, E; KATO, R; VASSANELLI, P	2
FRAHM, M; LOEBKENS, K; SOEHRING, K	1
BOUSQUET, WF; MIYA, TS; RUPE, BD	2
FRAHM, M; GOTTESLEBEN, A; SOEHRING, K	1
LECHAT, P; STREICHENBERGER, G	1
ARUSHANIAN, EB; SHAPAVALOV, AI	1
CHIESARA, E; FRONTINO, G; KATO, R; VASSANELLI, P	1
CARPI, A; KRUPP, P	1
FINE, BC; MOLLOY, JO	1
REINERT, H	1
ALSLEBEN, B; LIEBENSCHUETZ, W; REMMER, H; SIEGERT, M	1
BOUSQUET, WF; DRIEVER, CW	1
LECHAT, P; MAGET, E; STREICHENBERGER, G	1
Lukashin, VG; Vshivtseva, VV	1
LARSON, E	1

Reviews

3 review(s) available for hexobarbital and pentobarbital

Article	Year
[Elimination of pain in laboratory animals]. Berliner und Munchener tierarztliche Wochenschrift, 1975, Aug-01, Volume: 88, Issue:15 Topics: Acepromazine; Anesthesia, General; Anesthetics; Animals; Animals, Laboratory; Azaperone; Chloroform; Chlorpromazine; Cricetinae; Dose-Response Relationship, Drug; Droperidol; Ethers; Gerbillinae; Guinea Pigs; Halothane; Hexobarbital; Imidazoles; Ketamine; Lethal Dose 50; Methoxyflurane; Mice; Pentobarbital; Rabbits; Rats; Swine; Urethane	1975
Circadian rhythms in effects of hypnotics and sleep inducers. International journal of clinical pharmacology research, 1986, Volume: 6, Issue:1 Topics: Adaptation, Physiological; Anesthetics; Animals; Biological Availability; Circadian Rhythm; Ethanol; Hexobarbital; Humans; Hypnotics and Sedatives; Kinetics; Pentobarbital; Psychomotor Performance; Rats; Sleep	1986
Sex-related differences in drug metabolism. Drug metabolism reviews, 1974, Volume: 3, Issue:1 Topics: Aniline Compounds; Animals; Benzopyrenes; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Electron Transport; Estradiol; Female; Hexobarbital; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADH, NADPH Oxidoreductases; Oxidoreductases, N-Demethylating; Pentobarbital; Pharmaceutical Preparations; Pharmacology; Phenobarbital; Proadifen; Rats; Sex Factors; Spectrophotometry; Spectrophotometry, Ultraviolet; Strychnine; Testosterone	1974

Other Studies

138 other study(ies) available for hexobarbital and pentobarbital

Article	Year
Correlation of biological activity and high-pressure liquid chromatographic retention index for a series of propranolol, barbiturate, and anthranilic acid analogues. Journal of medicinal chemistry, 1979, Volume: 22, Issue:11 Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Barbiturates; Cell Division; Chromatography, High Pressure Liquid; In Vitro Techniques; Myocardial Contraction; ortho-Aminobenzoates; Propranolol; Rabbits; Rats; Sleep; Solubility	1979
A simplified high-pressure liquid chromatography method for determining lipophilicity for structure-activity relationships. Journal of medicinal chemistry, 1983, Volume: 26, Issue:7 Topics: Animals; Bacteria; Barbiturates; Biological Assay; Cell Division; Chromatography, High Pressure Liquid; Female; Ovum; Oxygen Consumption; Rabbits; Solubility; Structure-Activity Relationship; Sulfanilamides	1983
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins. Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2 Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
[Determination of barbiturates from biological material]. Soudni lekarstvi, 1975, Volume: 20, Issue:3 Topics: Amobarbital; Barbital; Barbiturates; Chromatography, Gas; Forensic Medicine; Hexobarbital; Humans; Hydrogen-Ion Concentration; Pentobarbital; Phenobarbital	1975
Transport of heterocyclic acids across rat small intestine in vitro. The Journal of membrane biology, 1978, Jan-18, Volume: 38, Issue:3 Topics: Amobarbital; Animals; Barbital; Barbiturates; Biological Transport; Dimethadione; Hexobarbital; Hydrogen-Ion Concentration; In Vitro Techniques; Jejunum; Male; Oxazoles; Pentobarbital; Phenobarbital; Rats; Secobarbital	1978
[Effect of thiol compounds on experimental liver damage (III). Effect of tiopronin (2-mercaptopropionylglycine) and glutathione on drug metabolizing activity (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1979, Volume: 75, Issue:6 Topics: Amino Acids, Sulfur; Aminopyrine; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Ethionine; Female; Glutathione; Hexobarbital; Liver Diseases; Microsomes, Liver; NADH Dehydrogenase; NADPH-Ferrihemoprotein Reductase; Pentobarbital; Rats; Sleep; Tiopronin	1979
A correlation between hexobarbitone and pentobarbitone sleeping times in fifteen different inbred strains of mice (Mus musculus). General pharmacology, 1978, Volume: 9, Issue:3 Topics: Animals; Female; Hexobarbital; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Pentobarbital; Sex Factors; Sleep; Species Specificity; Time Factors	1978
[Effect of urethane (DAB-6 product), hexobarbital-Na and pentobarbital-Na on the amino acid concentrations in blood serum of rats. I. Communication (author's transl)]. Der Anaesthesist, 1977, Volume: 26, Issue:1 Topics: Amino Acids; Animals; Arginine; Chromatography, Ion Exchange; Hexobarbital; Isoleucine; Leucine; Lysine; Male; Methionine; Methods; Ornithine; Pentobarbital; Phenylalanine; Rats; Taurine; Tryptophan; Tyrosine; Urethane	1977
Hypoxia-induced vasoconstriction in isolated perfused lungs exposed to injectable or inhalation anesthetics. Acta anaesthesiologica Scandinavica, 1977, Volume: 21, Issue:2 Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Animals; Diazepam; Dose-Response Relationship, Drug; Droperidol; Ether; Fentanyl; Halothane; Hexobarbital; Hypoxia; Ketamine; Methoxyflurane; Nitrous Oxide; Partial Pressure; Pentazocine; Pentobarbital; Rats; Thiopental; Vasomotor System; Ventilation-Perfusion Ratio	1977
Inhibition of hepatic microsomal enzymes by chloramphenicol. The Journal of pharmacology and experimental therapeutics, 1977, Volume: 203, Issue:2 Topics: Animals; Benzphetamine; Chloramphenicol; Cytochrome P-450 Enzyme System; Drug Interactions; Ethylmorphine-N-Demethylase; Hexobarbital; In Vitro Techniques; Male; Mice; Microsomes, Liver; Oxidoreductases, N-Demethylating; Pentobarbital; Phenobarbital	1977
Inhibition of chemical induction of porphyrin synthesis in chick embryo liver cells by partially purified human chorionic gonadotropin. Biochemical and biophysical research communications, 1976, Jan-26, Volume: 68, Issue:2 Topics: 5-Aminolevulinate Synthetase; Aminopyrine; Animals; Chick Embryo; Chorionic Gonadotropin; Enzyme Induction; Etiocholanolone; Hexobarbital; Humans; Liver; Meprobamate; Molecular Weight; Pentobarbital; Porphyrins; Secobarbital	1976
Acute tolerance to barbiturate in the rat. European journal of pharmacology, 1976, Volume: 36, Issue:1 Topics: Animals; Barbital; Barbiturates; Brain; Disease Models, Animal; Drug Tolerance; Female; Hexobarbital; Humans; Male; Pentobarbital; Rats; Sleep; Substance-Related Disorders; Time Factors	1976
[New data on the use of the hexenal test in a toxicological experiment]. Gigiena truda i professional'nye zabolevaniia, 1976, Issue:10 Topics: Animals; Butadienes; Carbon Tetrachloride; Enzyme Activation; Hexobarbital; Hydrocarbons, Chlorinated; Male; Microsomes, Liver; Oxidoreductases; Pentobarbital; Rats; Toxicology	1976
Influence of surgical manipulations on hexobarbital effects in rats. Pharmacology, 1976, Volume: 14, Issue:6 Topics: Anesthesia, General; Animals; Brain; Half-Life; Hexobarbital; Lymph; Lymph Node Excision; Lymph Nodes; Male; Muscles; Pentobarbital; Rats; Time Factors	1976
Gas chromatographic method for the microdetermination of barbiturates in blood using a nitrogen-selective flame ionization detector. Journal of chromatography, 1975, Feb-19, Volume: 105, Issue:1 Topics: Barbiturates; Chromatography, Gas; Hexobarbital; Hot Temperature; Humans; Microchemistry; Nitrogen; Pentobarbital; Secobarbital; Solvents; Time Factors	1975
Proceedings: The effect of barbiturates on EEG in rats. I. The problem of data reduction (preliminary results). Activitas nervosa superior, 1975, Volume: 17, Issue:4 Topics: Animals; Barbiturates; Brain; Electroencephalography; Hexobarbital; Pentobarbital; Rats	1975
Effects of 1,1,1-trichloroethane administered by different routes and in different solvents on barbiturate hypnosis and metabolism in mice. Journal of toxicology and environmental health, 1976, Volume: 1, Issue:5 Topics: Administration, Topical; Aerosols; Animals; Hexobarbital; Injections, Intraperitoneal; Liver; Male; Mice; Oxidoreductases; Pentobarbital; Sleep; Time Factors; Trichloroethylene	1976
Effect of glucose administration on various rat hepatic constituents and on the spectral binding of hexobarbital and methadone to rat hepatic cytochrome P450. Pharmacology, 1989, Volume: 38, Issue:2 Topics: Animals; Cholesterol; Cytochrome P-450 Enzyme System; Glucose; Hexobarbital; Lipid Metabolism; Liver; Liver Glycogen; Male; Methadone; Microsomes, Liver; Pentobarbital; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains	1989
Comparative study on barbiturates using isolated single neurons: GABA-mimetic action and augmentatory action on GABA response. Brain research, 1989, May-29, Volume: 488, Issue:1-2 Topics: Animals; Barbiturates; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; Hexobarbital; In Vitro Techniques; Membrane Potentials; Pentobarbital; Ranidae; Secobarbital	1989
A simple and rapid high-pressure liquid chromatographic assay for pentobarbital and other barbiturates in serum. American journal of veterinary research, 1988, Volume: 49, Issue:5 Topics: Animals; Barbiturates; Chromatography, High Pressure Liquid; Hexobarbital; In Vitro Techniques; Pentobarbital; Phenobarbital; Rabbits	1988
Characterization of barbiturate-stimulated chloride efflux from rat brain synaptoneurosomes. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1985, Volume: 5, Issue:11 Topics: Amobarbital; Animals; Barbiturates; Bicuculline; Brain; Cell Membrane Permeability; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Hexobarbital; Male; Mephobarbital; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Rubidium; Secobarbital; Synapses	1985
Pipecolic acid antagonizes barbiturate-enhanced GABA binding to bovine brain membranes. Brain research, 1986, Apr-30, Volume: 372, Issue:1 Topics: Animals; Binding, Competitive; Brain; Cattle; Hexobarbital; Pentobarbital; Pipecolic Acids; Receptors, GABA-A; Synaptic Membranes	1986
Induction of alkoxyresorufin O-dealkylases, epoxide hydrolase, and liver weight gain: correlation with liver tumor-promoting potential in a series of barbiturates. Carcinogenesis, 1987, Volume: 8, Issue:1 Topics: 7-Alkoxycoumarin O-Dealkylase; Amobarbital; Animals; Barbital; Barbiturates; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Enzyme Induction; Epoxide Hydrolases; Hexobarbital; Isoenzymes; Liver; Liver Neoplasms; Male; Organ Size; Oxidoreductases; Oxygenases; Pentobarbital; Phenobarbital; Rats; Rats, Inbred F344	1987
Kinetics of hexobarbital and dipyrone in critical care patients receiving high-dose pentobarbital. European journal of clinical pharmacology, 1987, Volume: 32, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Aminopyrine; Critical Care; Dipyrone; Drug Interactions; Female; Glucaric Acid; Hexobarbital; Humans; Kinetics; Male; Middle Aged; Pentobarbital	1987
Variation in pentobarbitone sleeping time in mice. 2. Variables affecting test results. Laboratory animals, 1986, Volume: 20, Issue:2 Topics: Age Factors; Animals; Body Weight; Dose-Response Relationship, Drug; Fasting; Female; Hexobarbital; Litter Size; Male; Mice; Mice, Inbred Strains; Pentobarbital; Research Design; Sleep	1986
Dietary fat unsaturation enhances drug metabolism in cebus but not in squirrel monkeys. The Journal of nutrition, 1985, Volume: 115, Issue:5 Topics: Animals; Antipyrine; Cebus; Chromatography, High Pressure Liquid; Dietary Fats; Drug Interactions; Fats, Unsaturated; Female; Half-Life; Hexobarbital; Injections, Intravenous; Male; Pentobarbital; Saimiri; Sex Factors; Sleep; Species Specificity	1985
Enzyme induction in sheep: effects of phenobarbital on in vivo and in vitro drug metabolism. American journal of veterinary research, 1972, Volume: 33, Issue:5 Topics: Anesthesia; Aniline Compounds; Animals; Antipyrine; Cytochromes; Dicumarol; Enzyme Induction; Female; Formaldehyde; Half-Life; Hexobarbital; Metabolic Clearance Rate; Microsomes, Liver; Pentobarbital; Phenobarbital; Phenols; Proteins; Sheep; Sleep; Sulfobromophthalein; Time Factors	1972
The effect of barbiturates on (3H)GABA transport in rat cerebral cortex slices. Brain research, 1974, Dec-06, Volume: 81, Issue:2 Topics: Aminobutyrates; Amobarbital; Animals; Binding, Competitive; Biological Transport; Cell Membrane; Cerebral Cortex; Depression, Chemical; Dose-Response Relationship, Drug; Drug Synergism; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Hexobarbital; Male; Ouabain; Pentobarbital; Phenobarbital; Potassium; Rats; Sodium; Stimulation, Chemical; Time Factors; Tritium	1974
Action of drugs on the electrical activity of the red nucleus. Electroencephalography and clinical neurophysiology, 1969, Volume: 27, Issue:3 Topics: Animals; Barbiturates; Cerebral Cortex; Chlordiazepoxide; Diazepam; Electrodes; Electrophysiology; Ethanol; Hexobarbital; Hippocampus; Male; Mephenesin; Meprobamate; Oxazepam; Pentobarbital; Phenobarbital; Rabbits; Red Nucleus; Thiopental; Urethane	1969
[Hepatic insufficiency and neurotropic medicinal activity]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1966, Volume: 160, Issue:4 Topics: Animals; Chemical and Drug Induced Liver Injury; Dogs; Drug Synergism; Female; Hexobarbital; Iproniazid; Lysergic Acid Diethylamide; Male; Pentobarbital; Rats; Reserpine	1966
[Species specific difference in binding to plasma proteins]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:1 Topics: Aminobenzoates; Aniline Compounds; Animals; Barbiturates; Blood Proteins; Cattle; Chlorpromazine; Dipyridamole; Dogs; Guanidines; Guinea Pigs; Hexobarbital; Methohexital; Mice; Nitrofurantoin; Pentobarbital; Phenylbutazone; Protein Binding; Rabbits; Rats; Salicylamides; Salicylates; Species Specificity; Sulfadimethoxine; Sulfaguanidine; Sulfinpyrazone; Sulfonamides; Swine; Thiopental	1967
[Influence of acidosis and alkalosis on the binding of drugs to plasma proteins]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2 Topics: Acidosis; Alkalosis; Aniline Compounds; Animals; Blood Proteins; Cattle; Chemical Phenomena; Chemistry; Chlorpromazine; Hexobarbital; Hydrogen-Ion Concentration; Methohexital; Nitrofurantoin; Pentobarbital; Phenylbutazone; Protein Binding; Quinine; Salicylamides; Salicylates; Thiopental	1968
[Demonstration of a depressive component in the central effects of nikethamide]. Archives des sciences physiologiques, 1972, Volume: 26, Issue:2 Topics: Animals; Body Temperature; Central Nervous System; Chloral Hydrate; Drug Synergism; Female; Hexobarbital; Hypnotics and Sedatives; Male; Mice; Niacinamide; Nikethamide; Pentobarbital; Proadifen; Sleep; Time Factors; Wakefulness	1972
Stress stimulation of drug metabolism in the rat. International journal of neuropharmacology, 1966, Volume: 5, Issue:2 Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Corticosterone; Dactinomycin; Hexobarbital; Hypophysectomy; In Vitro Techniques; Meprobamate; Pentobarbital; Phenobarbital; Pituitary Gland; Pituitary-Adrenal System; Rats; Stress, Physiological	1966
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism. Molecular pharmacology, 1966, Volume: 2, Issue:4 Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine	1966
Effect of starvation on the in vivo metabolism and effect of drugs in female and male rats. Japanese journal of pharmacology, 1967, Volume: 17, Issue:2 Topics: Amides; Anesthesia; Animals; Barbiturates; Body Weight; Carisoprodol; Diphosphates; Female; Hexobarbital; Kidney; Liver; Male; Organ Size; Paralysis; Pentobarbital; Phenobarbital; Rats; Starvation; Strychnine; Sucrose; Zoxazolamine	1967
Reticuloendothelial stimulation and drug metabolism. Journal of the Reticuloendothelial Society, 1970, Volume: 7, Issue:6 Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Barbiturates; Brain Chemistry; Corticosterone; Hexobarbital; Liver; Male; Mice; Mononuclear Phagocyte System; Organ Size; Pentobarbital; Sleep; Zymosan	1970
Comparative central activities of a new dihydrodibenzoxazepine antihistaminic and of pyrilamine. Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 160, Issue:1 Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System; Hexobarbital; Histamine H1 Antagonists; Movement; Pentobarbital; Rats; Sleep	1966
Possible role of P-450 in the oxidation of drugs in liver microsomes. Journal of biochemistry, 1966, Volume: 59, Issue:6 Topics: Aminopyrine; Aniline Compounds; Animals; Carisoprodol; Chlorpromazine; Cytochromes; Glutethimide; Hexobarbital; In Vitro Techniques; Liver; Microsomes; Oxidoreductases; Pentobarbital; Phenobarbital; Piperazines; Rats	1966
Taloximine, a new respiratory stimulant with brochodilator properties. British journal of pharmacology, 1969, Volume: 35, Issue:2 Topics: Anaphylaxis; Animals; Bronchi; Bronchodilator Agents; Cats; Dogs; Guinea Pigs; Heterocyclic Compounds; Hexobarbital; Histamine; Histamine H1 Antagonists; Humans; Mice; Morphine; Pentobarbital; Rabbits; Respiration; Stimulation, Chemical	1969
Pharmacological properties of AF 1161, a new psychotropic drug. International journal of neuropharmacology, 1968, Volume: 7, Issue:6 Topics: Amphetamine; Animals; Avoidance Learning; Cats; Chlordiazepoxide; Chlorpromazine; Conditioning, Psychological; Depression, Chemical; Dogs; Electroencephalography; Female; Guinea Pigs; Hexobarbital; Histamine H1 Antagonists; Male; Mice; Morphine; Motor Activity; Pentobarbital; Piperazines; Psychopharmacology; Pyridines; Rabbits; Rats; Reflex; Serotonin Antagonists; Sleep; Triazoles	1968
Species difference in the inhibition of drug metabolism by liver microsomes by different inhibitors. Japanese journal of pharmacology, 1969, Volume: 19, Issue:3 Topics: Aminopyrine; Aniline Compounds; Animals; Cocaine; Depression, Chemical; Drug Antagonism; Ethylamines; Hexobarbital; Histamine H1 Antagonists; Kinetics; Male; Meperidine; Mice; Microsomes, Liver; Morphine; Nitrophenols; Oxidation-Reduction; Pentobarbital; Pharmaceutical Preparations; Phenacetin; Phenylhydrazines; Piperazines; Proadifen; Rabbits; Rats; Species Specificity; Zoxazolamine	1969
Relationship between difference spectra and metabolism. Barbiturates, drug interaction and species difference. Biochemical pharmacology, 1970, Volume: 19, Issue:5 Topics: Acetanilides; Acetates; Amino Alcohols; Aminopyrine; Aniline Compounds; Animals; Barbiturates; Binding Sites; Chemical Phenomena; Chemistry; Chlorpromazine; Cytochromes; Drug Antagonism; Drug Synergism; Ethanolamines; Hexobarbital; Macaca; Male; Mice; Microsomes, Liver; Pentobarbital; Phenobarbital; Proadifen; Propranolol; Protein Binding; Rats; Sleep; Species Specificity; Spectrophotometry; Thiazoles; Tremorine	1970
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus. Biochemical pharmacology, 1970, Volume: 19, Issue:6 Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea	1970
A study of some possible mechanisms by which glucose inhibits drug metabolism in vivo and in vitro. The Journal of pharmacology and experimental therapeutics, 1972, Volume: 180, Issue:1 Topics: Animals; Barbiturates; Benzphetamine; Brain Chemistry; Carbon Isotopes; Electron Transport Complex IV; Glucose; Glucosephosphate Dehydrogenase; Hexobarbital; Kinetics; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; NADP; Organ Size; Oxidoreductases; Pentobarbital; Sleep	1972
A study of the interaction of a series of substituted barbituric acids with the hepatic microsomal monooxygenase. Archives of biochemistry and biophysics, 1972, Volume: 151, Issue:2 Topics: Amobarbital; Animals; Barbiturates; Cytochromes; Hexobarbital; Hydrogen-Ion Concentration; Lipids; Male; Microsomes, Liver; NAD; NADP; Oxygenases; Pentobarbital; Phenobarbital; Rats; Secobarbital; Solubility; Spectrophotometry	1972
Analeptic effects of N-sulfamoyl-hexahydro-azepine, SaH 41-178. Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 200, Issue:2 Topics: Analgesics; Animals; Azepines; Cardiovascular System; Cats; Central Nervous System; Central Nervous System Stimulants; Doxapram; Electrodes, Implanted; Electroencephalography; Hexobarbital; Male; Mice; Pentobarbital; Pentylenetetrazole; Respiratory System; Sleep; Sulfonamides	1972
Effects of barbiturates on synthesis and rapid axonal transport of protein in vitro in the sciatic system of the frog. Acta physiologica Scandinavica, 1974, Volume: 91, Issue:4 Topics: Animals; Anura; Axons; Biological Transport; Depression, Chemical; Ganglia, Spinal; Hexobarbital; Leucine; Ligation; Methohexital; Pentobarbital; Protein Biosynthesis; Sciatic Nerve; Thiopental; Time Factors; Trichloroacetic Acid; Tritium	1974
[Effects of picrotoxin and pentetrazol on experimental sleep in the mouse]. Archives des sciences physiologiques, 1974, Volume: 28, Issue:3 Topics: Animals; Brain Chemistry; Chloral Hydrate; Chlormethiazole; Hexobarbital; Pentobarbital; Pentylenetetrazole; Picrotoxin; Sleep; Time Factors	1974
Interaction of the imidazolone derivative GPA 1851 with hepatic microsomal drug metabolism. Pharmacology, 1972, Volume: 8, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Barbiturates; Benzene Derivatives; Benzopyrenes; Dogs; Drug Interactions; Drug Synergism; Female; Haplorhini; Hexobarbital; Hydroxylation; Imidazoles; Kinetics; Macaca; Microsomes, Liver; Mixed Function Oxygenases; Pentobarbital; Proadifen; Rats; Sleep; Time Factors	1972
A rapid micro-method for the screening and measurement of barbiturates and related compounds in plasma by gas-liquid chromatography. Journal of clinical pathology, 1972, Volume: 25, Issue:10 Topics: Amobarbital; Animals; Barbiturates; Blood Specimen Collection; Cattle; Chromatography, Gas; Evaluation Studies as Topic; Glutethimide; Hexobarbital; Humans; Methaqualone; Methods; Microchemistry; Pentobarbital; Phenobarbital; Secobarbital; Time Factors	1972
Acute lethality for mice following administration of cyclophosphamide with barbiturates. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 143, Issue:1 Topics: Aminopyrine; Animals; Cyclophosphamide; Drug Synergism; Hexobarbital; Lethal Dose 50; Liver; Mice; Mice, Inbred BALB C; Microsomes, Liver; Mortality; Pentobarbital; Phenobarbital	1973
Intratracheal instillation method for mouse lungs. Oncology, 1973, Volume: 27, Issue:5 Topics: Air Pollution; Anesthesia, General; Animals; Benzopyrenes; Carcinogens; Chloral Hydrate; Chloralose; Female; Hexobarbital; Hyperplasia; Intubation, Intratracheal; Iron; Lung; Lung Diseases; Lymphoid Tissue; Mice; Pentobarbital; Peritoneum; Succinylcholine	1973
Influence of different types of narcosis and of neck fracture on the concentration of glycolytic intermediates and related compounds in rat liver. Archives of biochemistry and biophysics, 1973, Volume: 158, Issue:1 Topics: Adenosine Monophosphate; Adenosine Triphosphate; Anesthetics; Animals; Citrates; Ethyl Ethers; Fractures, Bone; Glycerophosphates; Glycolysis; Halothane; Hexobarbital; Hexosephosphates; Lactates; Liver; Malates; Male; Neck; Oxaloacetates; Pentobarbital; Phenobarbital; Pyruvates; Rats; Time Factors; Urethane	1973
Alterations of barbiturate action following 1,1-dichloroethylene, corticosterone, or acrolein. Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 205, Issue:2 Topics: Acrolein; Aldehydes; Animals; Barbiturates; Brain Chemistry; Corticosterone; Drug Interactions; Ethylenes; Hexobarbital; Hydrocarbons, Chlorinated; Male; Motor Activity; Pentobarbital; Postural Balance; Rats; Sleep; Time Factors	1973
Genetic control of barbiturate depression: strain and sex variation. British journal of anaesthesia, 1973, Volume: 45, Issue:10 Topics: Anesthesia, General; Animals; Barbiturates; Drug Resistance; Female; Genotype; Hexobarbital; Male; Mice; Mice, Inbred Strains; Pentobarbital; Reflex; Sex Factors; Sleep; Time Factors	1973
Experimental models for the in vivo evaluation of enzyme induction properties of drugs. Arzneimittel-Forschung, 1973, Volume: 23, Issue:12 Topics: Acetanilides; Amides; Aminopyrine; Amphetamine; Aniline Compounds; Animals; Central Nervous System; Codeine; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Hexobarbital; Male; Meperidine; Mice; Oxotremorine; Pentobarbital; Phenacetin; Phenytoin; Rabbits; Rats; Strychnine; Tolbutamide; Tremorine; Zoxazolamine	1973
Influence of clofibrate (ethyl-4-chlorophenoxyisobutyrate) on hepatic drug metabolism in male rats. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 145, Issue:1 Topics: Age Factors; Aminopyrine; Aniline Compounds; Animals; Clofibrate; Cytochrome P-450 Enzyme System; Glucosephosphate Dehydrogenase; Hexobarbital; Hydroxylation; Liver; Male; Microsomes, Liver; Morphine; Pentobarbital; Proteins; Rats; Sleep; Zoxazolamine	1974
New approach to derivatization and gas-chromatographic analysis of barbiturates. Clinical chemistry, 1974, Volume: 20, Issue:2 Topics: Amobarbital; Barbiturates; Chromatography, Gas; Evaluation Studies as Topic; Hexobarbital; Humans; Mephobarbital; Methods; Pentobarbital; Phenobarbital; Secobarbital	1974
[Effect of diethyl ether, Epontol, Evipan and Nembutal on serological tests]. Zeitschrift fur Versuchstierkunde, 1974, Volume: 16, Issue:1 Topics: Anesthesia, General; Animals; Diagnostic Errors; Ethyl Ethers; Female; Hexobarbital; Male; Pentobarbital; Propanidid; Rabbits; Serologic Tests	1974
Action of strychnine and central depressants on the cerebello-rubral system. Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 207, Issue:2 Topics: Action Potentials; Animals; Anticonvulsants; Benzodiazepinones; Cerebellum; Chlorobenzenes; Drug Interactions; Electrodes; Electroencephalography; Guaifenesin; Halothane; Hexobarbital; Male; Neurons; Nitro Compounds; Pentobarbital; Propanidid; Rabbits; Red Nucleus; Strychnine; Time Factors	1974
Biotransformation of thiopental and other thiobarbiturates. International anesthesiology clinics, 1974,Summer, Volume: 12, Issue:2 Topics: Adipose Tissue; Anesthesia; Anesthesia, Intravenous; Animals; Barbiturates; Biotransformation; Brain; Carboxylic Acids; Dogs; Ethanol; Female; Hexobarbital; Humans; Ketones; Kidney; Lipids; Liver; Male; Microsomes, Liver; Muscles; Pentobarbital; Protein Binding; Rabbits; Rats; Solubility; Thiones; Thiopental	1974
The effect of pretreatment with dieldrin on certain in vivo parameters of enzyme induction in mice. Toxicology and applied pharmacology, 1974, Volume: 27, Issue:1 Topics: Animals; Barbiturates; Brain Chemistry; Cytochrome P-450 Enzyme System; Dieldrin; Enzyme Induction; Hexobarbital; Lethal Dose 50; Male; Mice; Microsomes, Liver; Pentobarbital; Phenobarbital; Sleep; Thiopental; Time Factors	1974
A new technique for solid injection in gas-liquid chromatography. Analysis of barbiturates in urine. Journal of chromatography, 1972, Mar-22, Volume: 66, Issue:1 Topics: Barbiturates; Chromatography, Gas; Ethers; Hexobarbital; Humans; Methods; Microchemistry; Pentobarbital; Phenobarbital	1972
The effects of anaesthetics on synaptic excitation and inhibition in the olfactory bulb. The Journal of physiology, 1972, Volume: 223, Issue:3 Topics: Acetates; Aminobutyrates; Anesthetics; Animals; Chloral Hydrate; Chloralose; Dendrites; Ethanol; Halothane; Hexobarbital; Limbic System; Neural Inhibition; Olfactory Bulb; Pentobarbital; Rabbits; Synapses; Urethane	1972
Simultaneous identification and quantitation of submicrogram amounts of barbiturates by gas chromatography. American journal of veterinary research, 1972, Volume: 33, Issue:1 Topics: Barbiturates; Chromatography, Gas; Hexobarbital; Methaqualone; Methods; Methohexital; Pentobarbital; Phenobarbital; Thiamylal; Thiopental	1972
Ethanol tolerance and ethanol-drug interactions in the rat. Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3 Topics: Animals; Barbiturates; Behavior, Animal; Body Weight; Depression, Chemical; Drug Interactions; Drug Tolerance; Ethanol; Female; Hexobarbital; Injections, Intraperitoneal; Male; Meprobamate; Motor Activity; Organ Size; Pentobarbital; Phenobarbital; Rats; Rats, Inbred Strains; Zoxazolamine	1972
A gas-chromatographic method for separating and measuring barbiturates and glutethimide in blood. Clinical chemistry, 1971, Volume: 17, Issue:10 Topics: Amobarbital; Barbiturates; Blood Chemical Analysis; Chloroform; Chromatography, Gas; Evaluation Studies as Topic; Glass; Glutethimide; Hexobarbital; Humans; Hydrogen-Ion Concentration; Mathematics; Mephobarbital; Methods; Methohexital; Methylation; Pentobarbital; Phenobarbital; Secobarbital; Solubility; Spectrophotometry; Time Factors; Ultraviolet Rays	1971
The diphasic action of halothane on the oxidative metabolism of drugs by the liver. An in-vitro study in the rat. Anesthesiology, 1971, Volume: 35, Issue:3 Topics: Acetanilides; Acetone; Aminopyrine; Amobarbital; Aniline Compounds; Animals; Biotransformation; Depression, Chemical; Enzyme Induction; Halothane; Hexobarbital; Hydroxylation; Male; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Pentobarbital; Rats; Zoxazolamine	1971
[Changes of drug effects caused by their metabolism in the liver]. Monatsschrift fur Kinderheilkunde, 1971, Volume: 119, Issue:7 Topics: Aminopyrine; Animals; Cytochromes; Dogs; Drug Stability; Endoplasmic Reticulum; Female; Fetus; Hexobarbital; Humans; Liver; Male; Metabolism; Mice; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Pregnancy; Rabbits; Rats; Thiopental	1971
Determination of barbiturates in blood by GLC. Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 34, Issue:2 Topics: Acetamides; Amobarbital; Aniline Compounds; Barbiturates; Chromatography, Gas; Hexobarbital; Humans; Methods; Methylation; Pentobarbital; Secobarbital; Silicon	1971
The potentiation of barbiturates by desipramine in the mouse: mechanism of action. The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:2 Topics: Animals; Barbiturates; Body Temperature; Brain Chemistry; Carbon Isotopes; Desipramine; Drug Synergism; Hexobarbital; Male; Mice; Pentobarbital; Time Factors; Urea	1971
Pharmacology of 1-(2-oxo-1-pyrrolidino)-4-(2-chloroethyl-methylamino)but-2-yne-HCl (DSO-16), I. Its central cholinomimetic and cholinolytic effects on mice. Acta physiologica Academiae Scientiarum Hungaricae, 1971, Volume: 40, Issue:3 Topics: Alkynes; Analgesia; Animals; Drug Antagonism; Drug Synergism; Female; Hexobarbital; Male; Methylamines; Mice; Myasthenia Gravis; Mydriatics; Nicotine; Nicotinic Acids; Parasympatholytics; Parasympathomimetics; Pentobarbital; Physostigmine; Pyrrolidinones; Tremor	1971
Effect of administration of 3-aminotriazole on the activity of microsomal drug-metabolizing enzyme systems of rat liver. Japanese journal of pharmacology, 1967, Volume: 17, Issue:1 Topics: Aminopyrine; Aniline Compounds; Animals; Blood Proteins; Brain; Brain Chemistry; Cytochromes; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Nitrobenzenes; Pentobarbital; Phenobarbital; Pigments, Biological; Rats; Spectrophotometry; Triazoles; Zoxazolamine	1967
Metabolism of drugs in old rats. II. Metabolism in vivo and effect of drugs in old rats. Japanese journal of pharmacology, 1968, Volume: 18, Issue:4 Topics: Aging; Anesthesia; Animals; Carisoprodol; Female; Hexobarbital; Injections, Intraperitoneal; Insecticides; Liver; Male; Microsomes; Paralysis; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Rats; Sex Factors; Strychnine; Time Factors; Zoxazolamine	1968
Differences in the oxidative metabolism of drugs by liver microsomes. Japanese journal of pharmacology, 1969, Volume: 19, Issue:1 Topics: Aminopyrine; Aniline Compounds; Animals; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Oxidation-Reduction; Oxidoreductases; Pentobarbital; Phenobarbital; Proadifen; Rats; Sex Factors; Starvation; Thyroxine; Zoxazolamine	1969
Decreased potency of CNS depressants after prolonged social isolation in mice. Psychopharmacologia, 1969, Volume: 15, Issue:2 Topics: Animals; Barbiturates; Chloral Hydrate; Hexobarbital; Hypnotics and Sedatives; Male; Mice; Microsomes, Liver; Organ Size; Pentobarbital; Social Isolation	1969
The effects of oestrogens and progestins on the response of mice to barbiturates. British journal of pharmacology, 1969, Volume: 37, Issue:1 Topics: Animals; Barbiturates; Body Temperature; Drug Synergism; Female; Hexobarbital; Lynestrenol; Male; Mestranol; Mice; Pentobarbital; Proadifen; Sleep; Time Factors	1969
Effect of drugs on red cell fragility. Nature, 1970, Mar-21, Volume: 225, Issue:5238 Topics: Acetylcholine; Amobarbital; Amphetamine; Atropine; Barbiturates; Bemegride; Cell Membrane; Chlorpromazine; Epinephrine; Erythrocytes; Hemolysis; Hexobarbital; Norepinephrine; Osmotic Fragility; Pentobarbital; Phentolamine; Physostigmine; Scopolamine; Thiopental	1970
[Electrocorticogram, steady potential of the brain and energy-rich phosphate fractions of the cerebral cortex during anesthetic overdosage, ischemia and cyanide poisoning]. Pflugers Archiv : European journal of physiology, 1970, Volume: 319, Issue:1 Topics: Adenine Nucleotides; Adenosine Triphosphate; Anesthetics; Animals; Cerebral Cortex; Chloral Hydrate; Chlorobutanol; Cyanides; Depression, Chemical; Electroencephalography; Ethers; Female; Guinea Pigs; Hexobarbital; Ischemia; Male; Membrane Potentials; Methoxyflurane; Pentobarbital; Phenobarbital; Phosphates; Phosphocreatine; Propanidid; Rats; Urethane	1970
Stimulation of barbiturate metabolism by spironolactone in mice. Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 187, Issue:1 Topics: Animals; Enzyme Induction; Hexobarbital; Male; Mice; Microsomes, Liver; Pentobarbital; Sleep; Spironolactone; Stimulation, Chemical	1970
Diurnal variation in sensitivity to and metabolism of barbiturate in the rat: lack of correlation between in vivo and in vitro findings. European journal of pharmacology, 1970, Volume: 12, Issue:3 Topics: Animals; Brain; Carbon Isotopes; Circadian Rhythm; Female; Hexobarbital; In Vitro Techniques; Liver; Pentobarbital; Rats	1970
Effect of SKF 525-A on biliary function. Influence of body temperature. Life sciences. Pt. 1: Physiology and pharmacology, 1970, Apr-15, Volume: 9, Issue:8 Topics: Animals; Bile; Biliary Tract; Body Temperature; Drug Synergism; Female; Hexobarbital; Pentobarbital; Proadifen; Rats	1970
Comparison of liver microsome enzyme systems and barbiturate sleep times in rats caged individually or communally. Biochemical pharmacology, 1970, Volume: 19, Issue:3 Topics: Adrenal Glands; Aniline Compounds; Animals; Barbiturates; Body Weight; Crowding; Hexobarbital; In Vitro Techniques; Liver; Male; Microsomes, Liver; Organ Size; Pentobarbital; Rats; Sleep; Time Factors	1970
Evidence for spironolactone as a possible inducer of liver microsomal enzymes in mice. Biochemical pharmacology, 1970, Volume: 19, Issue:8 Topics: Aniline Compounds; Animals; Body Weight; Enzyme Induction; Hexobarbital; Liver; Male; Metabolism; Mice; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; Organ Size; Oxidoreductases; Pentobarbital; Proteins; Sleep; Spironolactone; Testosterone	1970
Interaction of ethanol and pyrazole with hepatic microsomes. Biochemical and biophysical research communications, 1971, Jan-08, Volume: 42, Issue:1 Topics: Alcohol Oxidoreductases; Aniline Compounds; Animals; Cytochromes; Ethanol; Hexobarbital; In Vitro Techniques; Male; Microsomes, Liver; Mixed Function Oxygenases; Pentobarbital; Pyrazoles; Rats; Spectrophotometry	1971
Effect of tryptophan on toxicity and depressant effects of barbiturates and ethanol in rats. Toxicology and applied pharmacology, 1971, Volume: 18, Issue:3 Topics: Amino Acids; Animals; Central Nervous System; Depression, Chemical; Drug Antagonism; Ethanol; Hexobarbital; Immobilization; Lethal Dose 50; Male; Methionine; Pentobarbital; Rats; Sleep; Tryptophan	1971
The pharmacology and toxicology of midaflur. Toxicology and applied pharmacology, 1971, Volume: 18, Issue:4 Topics: Analgesics; Animals; Appetite; Avoidance Learning; Benzimidazoles; Body Temperature; Body Weight; Carbon Isotopes; Cardiovascular System; Cats; Central Nervous System; Chlordiazepoxide; Chlorpromazine; Decerebrate State; Diazepam; Dogs; Electroencephalography; Female; Glucuronates; Guinea Pigs; Hexobarbital; Imidazoles; Lethal Dose 50; Meprobamate; Mice; Muscle Relaxants, Central; Ovulation; Pentobarbital; Rabbits; Rats; Seizures; Tetrabenazine	1971
Separation of oxy- and thiobarbiturates by thin-layer chromatography. Analytical biochemistry, 1968, Volume: 23, Issue:1 Topics: Amobarbital; Barbiturates; Chromatography, Thin Layer; Hexobarbital; Methods; Methohexital; Pentobarbital; Phenobarbital; Secobarbital; Thiopental	1968
The hypnotic properties of 8-ethylthio-6-thiotheophylline sodium. Toxicology and applied pharmacology, 1968, Volume: 12, Issue:2 Topics: Amphetamine; Animals; Caffeine; Chloral Hydrate; Chlorpromazine; Dogs; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Male; Meprobamate; Methylphenidate; Mice; Morphine; Nalorphine; Nikethamide; Pentobarbital; Pentylenetetrazole; Phenobarbital; Rabbits; Rats; Reserpine; Sleep; Theophylline; Thiopental	1968
Hexobarbital (enhexymalum NFN) sleeping times and EEG threshold doses as measurements of tolerance to barbiturates in the rat. Acta pharmacologica et toxicologica, 1968, Volume: 26, Issue:1 Topics: Animals; Barbiturates; Drug Tolerance; Electroencephalography; Hexobarbital; Male; Pentobarbital; Rats; Sleep; Time Factors	1968
Responses of isolated, perfused rat and guinea pig lungs to barbiturates. Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 176, Issue:2 Topics: Animals; Female; Guinea Pigs; Hexobarbital; In Vitro Techniques; Lung; Male; Pentobarbital; Perfusion; Phenobarbital; Rats; Respiration; Species Specificity; Spirometry; Thiopental; Vascular Resistance	1968
[Behavior of energy-rich phosphates in the cerebral cortex during elimination of electrical activity by high doses of various anesthetics]. Archiv fur Toxikologie, 1968, Volume: 24, Issue:1 Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Blood Pressure; Cats; Cerebral Cortex; Chloral Hydrate; Electroencephalography; Electrophysiology; Guinea Pigs; Heart Rate; Hexobarbital; Methoxyflurane; Pentobarbital; Phenobarbital; Phenylacetates; Phosphates; Phosphocreatine; Rats; Respiration, Artificial; Urethane	1968
Inhibition of the action of antidiuretic hormone by thiobarbiturates in dogs, and on isolated frog skin. The Journal of physiology, 1969, Volume: 200, Issue:2 Topics: Animals; Anura; Barbiturates; Diuresis; Dogs; Hexobarbital; In Vitro Techniques; Pentobarbital; Skin; Thiopental; Vasopressins	1969
Barbiturate mortality in hypothyroid and hyperthyroid rats. Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:2 Topics: Amobarbital; Animals; Barbiturates; Basal Metabolism; Body Temperature; Body Weight; Hexobarbital; Hyperthyroidism; Hypothyroidism; Male; Pentobarbital; Phenobarbital; Rats; Thiopental; Thyroidectomy; Triiodothyronine; Zoxazolamine	1969
[Identification of barbiturate metabolites by means of mass spectrometry and infrared spectroscopy]. Archiv fur Toxikologie, 1969, Volume: 25, Issue:2 Topics: Amobarbital; Barbiturates; Cycloheptanes; Hexobarbital; Infrared Rays; Methods; Pentobarbital; Phenobarbital; Spectrum Analysis	1969
Effect of anaesthetics on mature infections of Schistosoma mansoni in the white mouse. Nature, 1965, May-29, Volume: 206, Issue:987 Topics: Amobarbital; Animals; Barbiturates; Chloroform; Ethyl Ethers; Halothane; Hexobarbital; In Vitro Techniques; Liver Circulation; Mesenteric Arteries; Mesenteric Veins; Mice; Pentobarbital; Phenobarbital; Schistosoma; Schistosomiasis; Secobarbital	1965
Inhibition of drug metabolism in the mouse by a hypocholesterolemic agent, AY-9944. Experientia, 1964, Sep-15, Volume: 20, Issue:9 Topics: Animals; Anticholesteremic Agents; Body Temperature; Carisoprodol; Chlorpromazine; Cholinesterase Inhibitors; Hexobarbital; Hypothermia, Induced; In Vitro Techniques; Liver; Meprobamate; Mice; Pentobarbital; Strychnine	1964
Lycorine inhibition of drug metabolism and ascorbic acid biosynthesis in the rat. Biochemical pharmacology, 1966, Volume: 15, Issue:3 Topics: Alkaloids; Amines; Animals; Ascorbic Acid; Barbiturates; Hexobarbital; In Vitro Techniques; Liver; Meprobamate; Pentobarbital; Proadifen; Rats	1966
Identification of some barbiturates by paper and thin-layer chromatography. Journal of pharmaceutical sciences, 1966, Volume: 55, Issue:4 Topics: Amobarbital; Barbiturates; Chromatography, Paper; Chromatography, Thin Layer; Hexobarbital; Pentobarbital; Phenobarbital; Secobarbital	1966
Prolongation of barbiturate sleeping time in mice by stimulation of the reticuloendothelial system (RES). Journal of the Reticuloendothelial Society, 1966, Volume: 3, Issue:1 Topics: Animals; Barbiturates; Hexobarbital; Liver; Liver Glycogen; Lung; Mice; Mononuclear Phagocyte System; Pentobarbital; Phagocytosis; Sleep; Spleen; Zymosan	1966
Gas-liquid chromatography of submicrogram amounts of drugs. II. Analysis of barbiturates and related drugs in biological media. Journal of chromatography, 1966, Volume: 23, Issue:2 Topics: Amobarbital; Aspirin; Barbiturates; Bemegride; Caffeine; Chromatography, Gas; Glutethimide; Hexobarbital; Humans; Liver Extracts; Pentobarbital; Salicylates; Secobarbital	1966
The effect of DDD on barbiturate and steroid-induced hypnosis in the dog and rat. Biochemical pharmacology, 1966, Volume: 15, Issue:12 Topics: Amobarbital; Animals; Cortisone; Desoxycorticosterone; Dichlorodiphenyldichloroethane; Dogs; Drug Antagonism; Drug Synergism; Endoplasmic Reticulum; Female; Hexobarbital; Hydrocarbons, Halogenated; Liver; Male; Microscopy, Electron; Pentobarbital; Progesterone; Rats; Secobarbital; Sleep	1966
Modification of pharmacological activity following x-irradiation. Radiation research, 1967, Volume: 30, Issue:2 Topics: Animals; Barbiturates; Biotransformation; Brain; Hexobarbital; Pentobarbital; Radiation Effects; Rats; Serotonin; Thiopental	1967
The induction of drug-metabolizing enzymes in rat liver during growth and regeneration. A biochemical and ultrastructural study. Laboratory investigation; a journal of technical methods and pathology, 1967, Volume: 16, Issue:2 Topics: Animals; Butylene Glycols; Endoplasmic Reticulum; Enzyme Induction; Female; Hepatectomy; Hexobarbital; Liver; Liver Regeneration; Microscopy, Electron; Microsomes; Pentobarbital; Phenobarbital; Rats; Strychnine; Tranquilizing Agents	1967
[Influence of environmental temperature on the duration of experimental sleep and cerebral metabolism of hypnotics in rodents]. Archives des sciences physiologiques, 1967, Volume: 21, Issue:4 Topics: Alcohols; Animals; Brain; Chloral Hydrate; Hexobarbital; Hypothermia; Mice; Pentobarbital; Rats; Sleep; Temperature; Time Factors; Trichloroacetic Acid	1967
[Effect of diazepam and barbiturates on the in vivo metabolism of halothane and enflurane in rats]. Der Anaesthesist, 1983, Volume: 32, Issue:8 Topics: Animals; Barbiturates; Diazepam; Dose-Response Relationship, Drug; Enflurane; Half-Life; Halothane; Hexobarbital; Male; Methohexital; Pentobarbital; Rats; Rats, Inbred Strains; Thiopental	1983
Potencies of barbiturates in mice selectively bred for resistance or susceptibility to nitrous oxide anesthesia. Anesthesia and analgesia, 1984, Volume: 63, Issue:1 Topics: Anesthesia; Animals; Barbital; Barbiturates; Drug Resistance; Hexobarbital; Mice; Mice, Inbred Strains; Nitrous Oxide; Pentobarbital; Reflex; Secobarbital; Sleep	1984
Effect of ozone on drug-induced sleeping time in mice pretreated with mixed-function oxidase inducers and inhibitors. Toxicology and applied pharmacology, 1982, Mar-15, Volume: 62, Issue:3 Topics: Animals; Drug Interactions; Enzyme Induction; Female; Hexobarbital; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mixed Function Oxygenases; Oxidoreductases; Ozone; Paralysis; Pentobarbital; Sleep; Thiopental; Zoxazolamine	1982
Effect of doxapram on the action of other drugs and the hepatic drug-metabolizing system in mice. Japanese journal of pharmacology, 1982, Volume: 32, Issue:4 Topics: Aminopyrine; Animals; Body Temperature; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Doxapram; Drug Interactions; Hexobarbital; Liver; Male; Mice; Pentobarbital; Sleep	1982
Twenty-four hour toxicity rhythms of sedative-hypnotic drugs in mice. Archives of toxicology, 1980, Volume: 45, Issue:1 Topics: Animals; Circadian Rhythm; Hexobarbital; Hypnotics and Sedatives; Lethal Dose 50; Male; Mice; Pentobarbital; Secobarbital; Time Factors	1980
Study of lot-to-lot reproducibilities of Bond Elut Certify and Clean Screen DAU mixed-mode solid-phase extraction columns in the extraction of drugs from whole blood. Journal of chromatography, 1993, Jul-23, Volume: 617, Issue:1 Topics: Animals; Cattle; Chromatography, Liquid; Hexobarbital; Mepivacaine; Methamphetamine; Pentobarbital; Pharmaceutical Preparations; Prazepam; Reproducibility of Results; Trimipramine	1993
Pentobarbital decreases the gamma-aminobutyric acidA receptor subunit gamma-2 long/short mRNA ratio by a mechanism distinct from receptor occupation. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:1 Topics: Animals; Ethanol; GABA Modulators; Hexobarbital; Pentobarbital; Picrotoxin; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA Splicing; RNA, Messenger	1997
Effect of diacetylmonoxime on the action of convulsant and sedative-hypnotic barbiturates. The Journal of pharmacology and experimental therapeutics, 1962, Volume: 137 Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Barbiturates; Convulsants; Diacetyl; Hexobarbital; Hydroxylamines; Hypnotics and Sedatives; Pentobarbital	1962
Effect of sodium pentobarbital and sodium hexobarbital anesthesia on the adrenal 17-hydroxycorticosteroid secretion rate in the dog. Endocrinology, 1962, Volume: 70 Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Anesthesia; Animals; Dogs; Hexobarbital; Humans; Pentobarbital; Sodium	1962
Rapid differentiation of barbiturates in blood serum by thin-layer chromatography. Scandinavian journal of clinical and laboratory investigation, 1962, Volume: 14 Topics: Amobarbital; Barbiturates; Chromatography; Chromatography, Thin Layer; Hexobarbital; Pentobarbital; Phenobarbital; Serum	1962
[Effect of narcotics, analeptics, secale preparations and phenothiazine derivatives on the vagal respiratory and circulatory reflexes in the rat and guinea pig]. Medicina experimentalis : International journal of experimental medicine, 1962, Volume: 7 Topics: Animals; Bemegride; Blood Circulation; Central Nervous System Stimulants; Chloralose; Chlorpromazine; Ergot Alkaloids; Guinea Pigs; Hexobarbital; Morphine; Narcotics; Pentobarbital; Pentylenetetrazole; Promazine; Promethazine; Rats; Reflex; Respiration; Secale; Thiopental; Vagus Nerve	1962
A comparison of the effects of six barbiturates and a placebo on insomnia and motility in psychiatric patients. British journal of pharmacology and chemotherapy, 1963, Volume: 20 Topics: Barbiturates; Double-Blind Method; Female; Hexobarbital; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pentobarbital; Phenobarbital; Secobarbital; Sleep; Sleep Initiation and Maintenance Disorders	1963
Mechanism of potentiation of barbiturates and mepbrobamate actions by imipramine. Biochemical pharmacology, 1963, Volume: 12 Topics: Barbiturates; Chloral Hydrate; Hexobarbital; Imipramine; Meprobamate; Muscle Relaxants, Central; Pentobarbital	1963
[The influence of subchronic alcohol doses on barbiturate narcosis in the guinea pig]. Arzneimittel-Forschung, 1962, Volume: 12 Topics: Barbiturates; Ethanol; Guinea Pigs; Hexobarbital; Pentobarbital; Stupor	1962
STRESS MODIFICATION OF DRUG RESPONSE. Science (New York, N.Y.), 1963, Sep-20, Volume: 141, Issue:3586 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Corticosterone; Drug Tolerance; Hexobarbital; Meprobamate; Morphine; Pentobarbital; Pituitary Gland; Rats; Research; Stress, Physiological	1963
[IDENTIFICATION OF SEDATIVES IN AQUEOUS SOLUTIONS AND URINE BY THIN-LAYER CHROMATOGRAPHY]. Pharmaceutica acta Helvetiae, 1963, Volume: 38 Topics: Barbiturates; Bemegride; Chromatography; Chromatography, Thin Layer; Glutethimide; Hexobarbital; Hypnotics and Sedatives; Pentobarbital; Phenobarbital; Research; Thalidomide; Thiopental; Urine	1963
FURTHER STUDIES ON THE INHIBITION AND STIMULATION OF MICROSOMAL DRUG METABOLIZING ENZYMES OF RAT LIVER BY VARIOUS COMPOUNDS. Biochemical pharmacology, 1964, Volume: 13 Topics: Carisoprodol; Enzyme Inhibitors; Hexobarbital; Liver; Meprobamate; Metabolism; Pentobarbital; Pharmacology; Rats; Research; Strychnine	1964
[ON INDUCED RE-SOPORIFICATION IN THE RAT BY A SUDDEN CHANGE OF ENVIRONMENTAL TEMPERATURE]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Jan-06, Volume: 258 Topics: Chloral Hydrate; Hexobarbital; Hypnotics and Sedatives; Pentobarbital; Pharmacology; Pregnanediones; Rats; Research; Sleep; Temperature	1964
[EFFECT OF STIMULANTS AND DEPRESSANTS ON THE ACTIVITY OF SINGLE NEURONS OF THE SPINAL CORD FOLLOWING CEREBELLAR STIMULATION]. Biulleten' eksperimental'noi biologii i meditsiny, 1964, Volume: 57 Topics: Brain; Caffeine; Cats; Cerebellum; Electric Stimulation; Electrophysiology; Hexobarbital; Neurons; Pentobarbital; Pentylenetetrazole; Pharmacology; Piperidines; Research; Spinal Cord; Spinal Nerves; Urethane	1964
VARIATION IN THE ACTIVITY OF LIVER MICROSOMAL DRUG-METABOLIZING ENZYMES IN RATS IN RELATION TO THE AGE. Biochemical pharmacology, 1964, Volume: 13 Topics: Aging; Animals, Newborn; Carisoprodol; Diphosphates; Hexobarbital; Insecticides; Liver; Meprobamate; Metabolism; Microsomes; NADP; Oxidoreductases; Pentobarbital; Pharmacology; Rats; Research; Seizures; Strychnine; Toxicology	1964
[THE RELATION BETWEEN THE CEREBROVASCULAR AND ELECTROGRAPHIC EFFECT OF HYPERCAPNIA UNDER THE INFLUENCE OF BARBITURATES]. Helvetica physiologica et pharmacologica acta, 1964, Volume: 22 Topics: Animals; Barbiturates; Brain; Carbon Dioxide; Cerebrovascular Circulation; Dogs; Electrophysiological Phenomena; Electrophysiology; Hexobarbital; Hypercapnia; Hypoxia, Brain; Pentobarbital; Pharmacology; Research; Thiopental	1964
EFFECTS OF INSECTICIDE SYNERGISTS ON DURATION OF SLEEP INDUCED IN MICE BY BARBITURATES. Nature, 1964, Nov-21, Volume: 204 Topics: Anesthesia; Anesthesia, Intravenous; Anesthesiology; Animals; Barbiturates; Drug Synergism; Hexobarbital; Injections, Intraperitoneal; Insecticides; Mice; Pentobarbital; Pharmacology; Research; Sleep	1964
URETHANE HYPERGLYCAEMIA AND HYPOTHALAMIC ACTIVATION. Nature, 1964, Nov-28, Volume: 204 Topics: Adrenalectomy; Brain; Cats; Chloralose; Denervation; Dibenzylchlorethamine; Guanethidine; Hexamethonium Compounds; Hexobarbital; Hyperglycemia; Hypothalamus; Injections; Injections, Intraperitoneal; Pentobarbital; Pharmacology; Rabbits; Research; Reserpine; Sympatholytics; Toxicology; Urethane	1964
[DIFFERENCES IN MICROSOMAL OXIDATION AND ACETYLATION OF DRUGS IN DIFFERENT SPECIES AND RACES]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1964, Jul-28, Volume: 247 Topics: Acetylation; Aminopyrine; Dogs; Hexobarbital; Liver; Metabolism; Microsomes; Oxidation-Reduction; Pentobarbital; Rats; Research; Species Specificity; Thiopental; Toxicology	1964
ENDOCRINE MODIFICATION OF DRUG RESPONSES IN THE RAT. The Journal of pharmacology and experimental therapeutics, 1965, Volume: 147 Topics: Adrenalectomy; Adrenocorticotropic Hormone; Ascorbic Acid; Barbiturates; Corticosterone; Hexobarbital; Histamine; Hypophysectomy; Injections, Intraperitoneal; Meprobamate; Pentobarbital; Pharmacology; Phenobarbital; Rats; Research; Stress, Physiological; Zoxazolamine	1965
STRESS-DRUG INTERACTIONS: EVIDENCE FOR RAPID ENZYME INDUCTION. Life sciences (1962), 1965, Volume: 4 Topics: Adrenalectomy; Adrenocorticotropic Hormone; Blood; Corticosterone; Dactinomycin; Drug Interactions; Enzyme Induction; Hexobarbital; Hypophysectomy; Liver; Meprobamate; Metabolism; Morphine; Pentobarbital; Pharmacology; Phenobarbital; Physiology; Rats; Research; Stress, Physiological	1965
[PHARMACOLOGIC STUDY OF RETURN TO SLEEP INDUCED IN THE RAT BY SUDDEN CHANGE IN ENVIRONMENTAL TEMPERATURE]. Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1965, Volume: 13 Topics: Adrenalectomy; Amphetamine; Amphetamines; Caffeine; Chloral Hydrate; Cocaine; Dihydroergotoxine; Ergot Alkaloids; Hexobarbital; Hypnotics and Sedatives; Iproniazid; Pentobarbital; Pentylenetetrazole; Pharmacology; Pregnanediones; Rats; Research; Reserpine; Sleep; Temperature; Yohimbine	1965
[Morpho-functional changes in the frog urinary bladder receptors under the influence of barbiturates]. Morfologiia (Saint Petersburg, Russia), 2009, Volume: 136, Issue:6 Topics: Animals; Hexobarbital; Hypnotics and Sedatives; In Vitro Techniques; Nociceptors; Pentobarbital; Rana temporaria; Urinary Bladder	2009
The effect of pentobarbital sodium, evipal sodium and demerol on the action of insulin. Federation proceedings, 1946, Volume: 5, Issue:1 Pt 2 Topics: Barbital; Barbiturates; Hexobarbital; Insulin; Meperidine; Pentobarbital; Sodium	1946