hexobarbital has been researched along with nortriptyline in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bobkiewicz, T; Chodera, A; Nowakowska, E; Okulicz-Kozaryn, I | 1 |
| Orrenius, S; Schenkman, JB; von Bahr, C; Wilson, BJ | 1 |
| Brodin, A | 1 |
| O'Malley, K; Sawyer, PR; Stevenson, IH | 1 |
| Orrenius, S; Schenkman, JB; von Bahr, C | 1 |
| Grundin, R; Moldéus, P; Orrenius, S; von Bahr, C | 1 |
| Orrenius, S; Schenkman, JB; Von Bahr, C; Wilson, B | 1 |
| Galantay, E; Gogerty, J; Hoffman, C; Iorio, L; Leslie, G; Paolella, N; Trapold, JH | 1 |
1 review(s) available for hexobarbital and nortriptyline
| Article | Year |
|---|---|
On the significance of drug-induced spectral changes in liver microsomes.
Topics: Alkaloids; Amphetamine; Aniline Compounds; Animals; Binding Sites; Cytochrome P-450 Enzyme System; Desipramine; Hexobarbital; Hydroxylation; Microsomes, Liver; NADP; Nortriptyline; Oxidoreductases; Phenacetin; Rats; Spectrum Analysis; Testosterone; Tryptophan | 1972 |
11 other study(ies) available for hexobarbital and nortriptyline
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Influence of tricyclic antidepressant drugs on experimental arterial hypertension.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Female; Hexobarbital; Hypertension; Imipramine; Kidney; Male; Nephrectomy; Nortriptyline; Opipramol; Rats | 1975 |
Rates of transfer of organic protolytic solutes between an aqueous and an organic phase. 3. Mass transfer between water and some polar organic liquids.
Topics: Acetates; Alprenolol; Ephedrine; Fatty Alcohols; Hexobarbital; Hydrogen-Ion Concentration; Ketones; Methods; Nortriptyline; Solubility; Solvents; Spectrophotometry, Ultraviolet; Water | 1974 |
Proceedings: Effect of tricyclic antidepressants on drug metabolism.
Topics: Adult; Amitriptyline; Animals; Antidepressive Agents; Antipyrine; Desipramine; Dibenzazepines; Female; Half-Life; Hexobarbital; Humans; Imipramine; Liver; Male; Nortriptyline; Rats | 1972 |
Effect of phenobarbital and 3,4-benzpyrene treatment of rats on the microsomal binding and hydroxylation of nortriptyline and desmethyl-imipramine: evidence for qualitative changes in cytochrome P-450-ligand interaction following phenobarbital pretreatmen
Topics: Animals; Benzopyrenes; Binding Sites; Chromatography, Gas; Cytochrome P-450 Enzyme System; Desipramine; Hexobarbital; Ligands; Male; Microsomes, Liver; Mixed Function Oxygenases; Nortriptyline; Phenobarbital; Protein Binding; Rats; Receptors, Drug; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1972 |
Spectral studies on drug-cytochrome P-450 interaction in isolated rat liver cells.
Topics: Animals; Binding Sites; Cytochrome P-450 Enzyme System; Hexobarbital; Humans; Kinetics; Lidocaine; Liver; Male; Nortriptyline; Phenobarbital; Protein Binding; Rats; Spectrophotometry; Substance-Related Disorders; Time Factors | 1973 |
The significance of drug-induced spectral changes in liver microsomal fraction.
Topics: Animals; Binding Sites; Cytochromes; Hexobarbital; Methylcholanthrene; Microsomes, Liver; Naphthalenes; Nortriptyline; Oxidoreductases; Phenacetin; Rabbits; Spectrum Analysis | 1971 |
Dibenz[c,d,h]azulenes. II. "Bridged" amitriptyline analogs.
Topics: Amitriptyline; Amphetamine; Animals; Biological Assay; Body Temperature; Central Nervous System; Chemical Phenomena; Chemistry; Hexobarbital; Hypothermia, Induced; Mice; Nortriptyline; Reserpine; Sympathetic Nervous System; Sympathomimetics; Terpenes | 1969 |