hexobarbital and nadp

hexobarbital has been researched along with nadp in 95 studies

Research

Studies (95)

TimeframeStudies, this research(%)All Research%
pre-199094 (98.95)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (1.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brand, K; Junge, O1
Sies, H2
Baron, J; Matsubara, T; Peterson, JA; Peterson, LL1
Klinger, W; Muller, D1
Dvorchik, BH; Hartman, RD; Marietta, MP; Vesell, ES; Weisz, J1
Kauffman, FC; Reinke, LA; Thurman, RG1
Kageura, E; Toki, S2
Ahmad, N; Bederka, JP; Davitiyananda, D; Moses, ML1
Illing, A; Netter, KJ; Paul, H1
Jansson, I; Schenkman, JB1
Gillette, JR; Mitchell, JR; Sasame, HA; Thorgeirsson, SS1
Bridges, JW; Elcombe, CR; Illing, HP; King, LJ; Netter, KJ; Nimmo-Smith, RH; Wolf, CR1
Hayashi, N; Kamada, T; Kasahara, A; Peterson, JA; Sato, N1
Freytag, A; Klinger, W; Schmitt, W1
Kaul, KL; Novak, RF1
Dânşoreanu, MM; Telia, MI1
Eklöw-Låstbom, L; Moldéus, P; Orrenius, S1
Miyazaki, Y; Motohashi, Y; Takano, T1
Orrenius, S; Schenkman, JB; von Bahr, C; Wilson, BJ1
Carlson, GP; DeFeo, JJ; Springfield, AC1
Rösen, P; Stier, A1
Franklin, MR2
Wilson, JT1
Pelkonen, O1
Estabrook, RW; Werringloer, J1
Bergheim, P1
Richter, E; Rietbrock, I1
Bock, KW1
Blake, DA; Buterbaugh, GG; Weiner, M1
Lal, H; Roffman, M1
Baron, J; Estabrook, RW; Lambeth, D; Mason, JI; Waterman, M1
Conney, AH; Kuntzman, R; Welch, R1
Greene, FE; Hilliard, CC; Holl, JE; Molton, E; Wade, AE1
Cram, RL; Fouts, JR; Juchau, MR1
Fouts, JR; Gram, TE; Juchau, MR1
Kupfer, D; Peets, L2
Kato, R1
Estabrook, RW; Remmer, H; Schenkman, JB1
Fouts, JR; Gram, TE1
Gigon, PL; Gillette, JR; Gram, TE2
Coper, H; Veit, J; von Herrath, D1
Kato, R; Takanaka, A1
Kato, R; Takanaka, A; Takayanagi, M1
Gillette, JR; Sasame, HA1
Degkwitz, E; Staudinger, H; Ullrich, V1
Kato, R; Oshima, T; Takanaka, A1
Kato, R; Onoda, K; Takahashi, A; Takanaka, A1
Fouts, JR; Peters, MA2
Coon, MJ; Lu, AY; Strobel, HW1
Gillette, JR; Greene, FE; Stripp, B1
Leibman, KC1
Kupfer, D; Orrenius, S1
Donahue, JD; Johnson, RK; Jondorf, WR; Miller, HH1
Cohen, JL; Jao, JY1
Brauser, B; Sies, H1
Kato, R; Onoda, K; Sasajima, M1
Boréus, LO; Orrenius, S; Rane, A; Sjöqvist, F; Yaffe, SJ1
Fuller, GC; Lal, H; Olshan, A; Puri, SK1
Gillette, JR1
Baron, J; Estabrook, RW; Hildebrandt, AG; Leibman, K; Netter, KJ1
Darby, FJ; Newnes, W; Price Evans, DA1
Kato, R; Onoda, K1
Grosse, W; Wade, AE1
Arvela, P; Vorne, M1
Bousquet, WF; Leber, P1
Gillette, JR; Hamrick, M; Sasame, H; Stripp, B; Zampaglione, N1
Orrenius, S1
Feller, DR; Gerald, MC1
Peters, MA; Strother, A1
Gillette, JR; Hamrick, M; Stripp, B; Zampaglione, N1
Ernster, L; Jansson, I; Orrenius, S; Schenkman, JB1
Lazarus, G; Otterbein, A; Rietbrock, I1
Bousquet, WF; Fuller, GC; Miya, TS1
Becker, S; Brachtel, D; Richter, E; Zilly, W1
Stohs, SJ; Talcott, RE1
Cinti, DL; Moldeus, P; Schenkman, JB1
Gillette, JR; Hamrick, ME; Stripp, B; Zampaglione, NG1
Iyanagi, T; Kobayashi, S; Suzaki, T2
Heinemeyer, G; Hildebrandt, AG; Roots, I1
Sachan, DS1
Nakazawa, T; Yukawa, O1
BACQ, ZM; LIEBECQ, C; THOMOU, A1
TOKI, K; TSUKAMOTO, H1
DIXON, RL; FOUTS, JR; ROGERS, LA1
MANNERING, GJ; RUBIN, A; TEPHLY, TR1
CHIESARA, E; FRONTINO, G; KATO, R; VASSANELLI, P1
Arai, Y; Bunai, Y; El-Kabbani, O; Endo, S; Hara, A; Kitade, Y; Matsumoto, A; Matsunaga, T; Ohno, S; Tajima, K; Yamano, S1

Reviews

3 review(s) available for hexobarbital and nadp

ArticleYear
On the significance of drug-induced spectral changes in liver microsomes.
    Biochemical Society symposium, 1972, Volume: 34

    Topics: Alkaloids; Amphetamine; Aniline Compounds; Animals; Binding Sites; Cytochrome P-450 Enzyme System; Desipramine; Hexobarbital; Hydroxylation; Microsomes, Liver; NADP; Nortriptyline; Oxidoreductases; Phenacetin; Rats; Spectrum Analysis; Testosterone; Tryptophan

1972
Factors influencing steroid hydroxylases in liver microsomes.
    Advances in enzyme regulation, 1966, Volume: 4

    Topics: Age Factors; Animals; Carbon Isotopes; Chlordan; DDT; Dogs; Estradiol; Guinea Pigs; Hexobarbital; In Vitro Techniques; Insecticides; Liver; Mice; Microsomes; Mixed Function Oxygenases; NADP; Oxygen Consumption; Phenobarbital; Phenylbutazone; Phosphates; Polycyclic Compounds; Proadifen; Progesterone; Rabbits; Rats; Sex Factors; Steroids; Testosterone

1966
Current trends in hepatic response tests.
    Food and cosmetics toxicology, 1969, Volume: 7, Issue:4

    Topics: Aminopyrine; Animals; Ascorbic Acid; Circadian Rhythm; Cold Temperature; Cytochromes; DDT; Dietary Carbohydrates; Dietary Proteins; Dogs; Enzyme Induction; Guinea Pigs; Hepatomegaly; Hexobarbital; Humans; Hydrocarbons; Liver; Mice; Microsomes, Liver; NADP; Organ Size; Phenobarbital; Rabbits; Rats

1969

Other Studies

92 other study(ies) available for hexobarbital and nadp

ArticleYear
Mixed function oxidation of hexobarbital and generation of NADPH by the hexose monophosphate shunt in isolated rat liver cells.
    Archives of biochemistry and biophysics, 1975, Volume: 171, Issue:2

    Topics: Animals; Gluconeogenesis; Hexobarbital; Hexosephosphates; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Mixed Function Oxygenases; NADP; Oxidoreductases; Rats

1975
Proceedings: Monooxygenase activity and nicotinamide nucleotide systems in perfused rat liver.
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1975, Volume: 13, Issue:8

    Topics: Animals; Cytochrome P-450 Enzyme System; Hexobarbital; Liver; NADP; Nicotinamide Mononucleotide; Oxidation-Reduction; Phenobarbital; Rats

1975
NADPH-cytochrome P450 reductase.
    Archives of biochemistry and biophysics, 1976, Volume: 172, Issue:2

    Topics: Animals; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Hexobarbital; Kinetics; Male; Microsomes, Liver; Morphine Derivatives; NADP; Oxidation-Reduction; Rats; Structure-Activity Relationship

1976
Developmental aspects of xenobiotic transformation.
    Environmental health perspectives, 1976, Volume: 18

    Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Ethylmorphine; Female; Glucosephosphates; Hexobarbital; Hydrogen-Ion Concentration; Metyrapone; Microsomes, Liver; NAD; NADP; Niacinamide; Oxidoreductases, N-Demethylating; Oxidoreductases, O-Demethylating; Phenobarbital; Pregnancy; Rats; Semicarbazides

1976
Characterization of cytochrome P-450-dependent aminopyrine N-demethylase in rat brain: comparison with hepatic aminopyrine N-demethylation.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:2

    Topics: Aminopyrine N-Demethylase; Androstenedione; Aniline Compounds; Animals; Benzopyrenes; Brain; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hexobarbital; In Vitro Techniques; Kinetics; Male; Meperidine; Microsomes; Microsomes, Liver; NAD; NADP; Proadifen; Proteins; Rats

1979
Oxidation-reduction state of free NADP+ during mixed-function oxidation in perfused rat livers--Evaluation of the assumptions of near equilibrium by comparisons of surface fluorescence changes and calculated NADP+:NADPH ratios.
    Biochemical pharmacology, 1979, Aug-01, Volume: 28, Issue:15

    Topics: Animals; Female; Hexobarbital; Liver; Mixed Function Oxygenases; NAD; NADP; Nitroanisole O-Demethylase; Oxidation-Reduction; Oxidoreductases; Perfusion; Rats; Spectrometry, Fluorescence; Time Factors

1979
Guinea pig liver 3-hydroxyhexobarbital dehydrogenase. Purification and properties.
    The Journal of biological chemistry, 1975, Jul-10, Volume: 250, Issue:13

    Topics: Adrenal Glands; Alcohol Oxidoreductases; Animals; Chromatography; Dogs; Electrophoresis, Disc; Guinea Pigs; Hexobarbital; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; Isoelectric Focusing; Kidney; Kinetics; Liver; Lung; Mice; Molecular Weight; NAD; NADP; Phosphates; Rabbits; Rats

1975
Drug-biomolecule interactions: drug toxicity and vitamin coenzyme depletion.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:3

    Topics: Animals; Coenzymes; Female; Hexobarbital; Lethal Dose 50; Mice; Motor Activity; NADP; Niacinamide; Nicotinic Acids; Nucleotides; Rats; Sleep; Time Factors

1975
The effects of sulphydryl reagents on the binding and mixed function oxidation of hexobarbital in rat hepatic microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1975, Volume: 5, Issue:1

    Topics: Animals; Chloromercuribenzoates; Cysteamine; Cytochrome P-450 Enzyme System; Ethylmaleimide; Hexobarbital; Iodoacetamide; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen Consumption; Rats; Spectrophotometry; Sulfhydryl Reagents

1975
Interaction between microsomal electron transfer pathways.
    Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00

    Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Cytochrome Reductases; Cytochromes; Electron Transport; Ethylmorphine-N-Demethylase; Fatty Acids; Hexobarbital; Lipid Metabolism; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Peroxidases; Phenobarbital; Rats; Spectrum Analysis; Stearoyl-CoA Desaturase

1975
The role of cytochrome b5 in cytochrome P-450 enzymes.
    Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00

    Topics: Aminopyrine; Animals; Benzphetamine; Codeine; Cytochrome P-450 Enzyme System; Cytochromes; Electron Transport; Ethylmorphine-N-Demethylase; Hexobarbital; Hydroxylation; Kidney; Lauric Acids; Microsomes; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Pharmaceutical Preparations; Rats; Sheep

1975
Measurement of substrate-induced oxygen uptake during microsomal drug oxidation using a gold micro-electrode.
    Xenobiotica; the fate of foreign compounds in biological systems, 1975, Volume: 5, Issue:3

    Topics: Animals; Biphenyl Compounds; Cell-Free System; Gold; Hexobarbital; Kinetics; Male; Microelectrodes; Microsomes, Liver; Morphine; Morphine Derivatives; NADP; Naphthalenes; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Polarography; Proadifen; Rats

1975
Inhibition of cytochrome P-450-dependent mixed function oxidation by ethanol.
    Digestive diseases and sciences, 1985, Volume: 30, Issue:4

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Ethanol; Hexobarbital; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxygenases; Rats; Rats, Inbred Strains

1985
Influence of age, hexobarbital, and aniline on NADPH/NADH dependent hydrogen peroxide production in rat hepatic microsomes.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1986, Volume: 9

    Topics: Aging; Aniline Compounds; Animals; Cytochrome P-450 Enzyme System; Hexobarbital; Hydrogen Peroxide; In Vitro Techniques; Male; Microsomes, Liver; NAD; NADP; Rats; Rats, Inbred Strains

1986
Inhibition and induction of rabbit liver microsomal cytochrome P-450 by pyridine.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1

    Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Enzyme Induction; Ethanol; Hexobarbital; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Pyridines; Rabbits; Rats; Rats, Inbred Strains; Sleep

1987
Simultaneous photometric determination of oxygen consumption and NAD(P)H formation or disappearance using a continuous flow cuvette.
    Methods in enzymology, 1986, Volume: 122

    Topics: Animals; Autoanalysis; Bacteria; Cell Membrane; Hexobarbital; Kinetics; Microsomes, Liver; Mitochondria; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Oxygen Consumption; Rats; Spectrophotometry; Submitochondrial Particles

1986
On the mechanisms of glutathione depletion in hepatocytes exposed to morphine and ethylmorphine.
    Toxicology, 1986, Dec-01, Volume: 42, Issue:1

    Topics: Animals; Carmustine; Ethylmorphine; Glutathione; Glutathione Reductase; Hexobarbital; Hydrogen Peroxide; Liver; Male; Morphine; Morphine Derivatives; NADP; Rats; Rats, Inbred Strains

1986
Interaction of trichloroethane isomers with cytochrome P-450 in the perfused rat liver.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:2

    Topics: Animals; Cytochrome P-450 Enzyme System; Hemoglobins; Hexobarbital; Hydrocarbons, Chlorinated; In Vitro Techniques; Isomerism; Liver; Male; NAD; NADP; Oxygen Consumption; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Spectrophotometry; Trichloroethanes

1985
Liver enlargement and modification of hepatic microsomal drug metabolism in rats by pyrethrum.
    Toxicology and applied pharmacology, 1973, Volume: 24, Issue:2

    Topics: Aminopyrine; Animals; Anisoles; Body Weight; Chrysanthemum cinerariifolium; Colorimetry; Cytochrome Reductases; DNA; Dose-Response Relationship, Drug; Hepatomegaly; Hexobarbital; Inclusion Bodies; Liver; Male; Microsomes, Liver; NADP; Organ Size; Oxidation-Reduction; Pharmaceutical Preparations; Phytotherapy; Proteins; Rats; Spectrophotometry; Subcellular Fractions; Tryptophan Oxygenase; Water

1973
Kinetics of CO and O 2 complexes of rabbit liver microsomal cytochrome P 450 .
    Biochemical and biophysical research communications, 1973, Apr-02, Volume: 51, Issue:3

    Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hexobarbital; In Vitro Techniques; Kinetics; Microsomes, Liver; NADP; Oxygen Consumption; Phenobarbital; Photolysis; Protein Binding; Rabbits; Time Factors

1973
Piperonyl butoxide metabolism by cytochrome P-450: factors affecting the formation and disappearance of the metabolite-cytochrome P-450 complex.
    Xenobiotica; the fate of foreign compounds in biological systems, 1972, Volume: 2, Issue:6

    Topics: Animals; Cysteamine; Cytochrome P-450 Enzyme System; Dioxoles; Glucuronates; Hexobarbital; Kinetics; Male; Metyrapone; Mice; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Pesticide Synergists; Piperonyl Butoxide; Protein Binding; Rats; S-Adenosylmethionine; Spectrophotometry; Uridine Diphosphate Sugars

1972
Growth hormone modulation of liver drug metabolic enzyme activity in the rat. I. Effect of the hormone on the content and rate of reduction of microsomal cytochrome P-450.
    Biochemical pharmacology, 1973, Jul-15, Volume: 22, Issue:14

    Topics: Aniline Compounds; Animals; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Drug Stability; Growth Hormone; Hexobarbital; In Vitro Techniques; Liver; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats

1973
Drug metabolism and drug-induced spectral interactions in human fetal liver microsomes.
    Biochemical pharmacology, 1973, Oct-01, Volume: 22, Issue:19

    Topics: Adult; Aminopyrine; Aminopyrine N-Demethylase; Aniline Compounds; Animals; Benzopyrenes; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Fetus; Hexobarbital; Humans; In Vitro Techniques; Ligands; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxygenases; Pharmaceutical Preparations; Rats; Spectrophotometry

1973
Evidence for an inhibitory product-cytochrome P-450 complex generated during benzphetamine metabolism by liver microsomes.
    Life sciences, 1973, Nov-16, Volume: 13, Issue:10

    Topics: Aerobiosis; Animals; Appetite Depressants; Benzphetamine; Binding Sites; Cytochrome P-450 Enzyme System; Ethanol; Hexobarbital; Kinetics; Male; Microsomes, Liver; Morphine; NADP; Oxidoreductases, N-Demethylating; Phenethylamines; Protein Binding; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors

1973
Proceedings: The influence of steroids on microsomal NADH oxidation in rat liver and human placenta.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Androstenols; Animals; Female; Hexobarbital; Humans; In Vitro Techniques; Kinetics; Microsomes; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Placenta; Pregnancy; Rats; Steroids; Testosterone

1974
Proceedings: Comparison of the inducing effect of halothane and ethrane in rat liver.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Anesthetics; Animals; Cytochrome c Group; Cytochrome Reductases; Dealkylation; Enzyme Induction; Female; Halothane; Hexobarbital; Hydrocarbons, Halogenated; Liver; Methyl Ethers; Morphinans; NADP; Organ Size; Rats; Sleep; Time Factors

1974
Oxidation of barbiturates and the glucuronidation of 1-napthol in perfused rat liver and in microsomes.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 283, Issue:3

    Topics: Animals; Barbiturates; Biotransformation; Carbon Radioisotopes; Glucuronates; Half-Life; Hexobarbital; Hexosyltransferases; In Vitro Techniques; Kinetics; Liver; Male; Microsomes, Liver; NADP; Naphthols; Oxidation-Reduction; Perfusion; Phenobarbital; Rats

1974
Studies on the mechanism of inhibition of drug biotransformation by cyclic adenine nucleotides.
    Research communications in chemical pathology and pharmacology, 1972, Volume: 4, Issue:1

    Topics: Aniline Compounds; Animals; Biotransformation; Bucladesine; Cyclic AMP; Cytochrome P-450 Enzyme System; Depression, Chemical; Glucagon; Glucosephosphate Dehydrogenase; Glucosephosphates; Hexobarbital; In Vitro Techniques; Liver; Male; Microsomes, Liver; NADP; Rats; Theophylline; Time Factors

1972
Stimulus control of hexobarbital narcosis and metabolism in mice.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 191, Issue:3

    Topics: Air Movements; Animals; Appetitive Behavior; Behavior, Animal; Body Temperature; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Extinction, Psychological; Glucosephosphate Dehydrogenase; Half-Life; Hexobarbital; Hypoxia; Male; Mice; Microsomes, Liver; NADP; Physical Stimulation; Sleep; Time Factors

1974
The enzymic formation of methylenedioxyphenyl derivative exhibiting an isocyanide-like spectrum with reduced cytochrome P-450 in hepatic microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1971, Volume: 1, Issue:6

    Topics: Animals; Cyanides; Cytochrome P-450 Enzyme System; Dioxins; Dioxoles; Dithionite; Hexobarbital; Hydrogen-Ion Concentration; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Oxygen; Piperonyl Butoxide; Protein Binding; Rats; Spectrophotometry, Atomic

1971
Drugs, alcohol and sex hormones: a molecular perspective of the receptivity of cytochrome P-450.
    Annals of the New York Academy of Sciences, 1973, Volume: 212

    Topics: Adrenal Glands; Animals; Barbiturates; Binding, Competitive; Cattle; Cytochrome P-450 Enzyme System; Electron Transport; Estradiol; Ethanol; Gonadal Steroid Hormones; Hexobarbital; Microsomes; Microsomes, Liver; Mitochondria; Morphine Derivatives; NAD; NADP; Oxidation-Reduction; Phenobarbital; Testosterone

1973
Alteration of drug metabolism in rats and mice by an environment of cedarwood.
    Pharmacology, 1968, Volume: 1, Issue:5

    Topics: Aniline Compounds; Animals; Azo Compounds; Dextroamphetamine; Dicumarol; Environment; Glucose; Hexobarbital; Indenes; Liver; Magnesium Sulfate; Male; Mice; Microsomes; NADP; Naphthalenes; Niacinamide; Rats; Sleep; Sulfanilamides; Sulfonamides; Terpenes; Wood; Zoxazolamine

1968
Stimulation by chlordane of hepatic drug metabolism in the squirrel monkey.
    The Journal of laboratory and clinical medicine, 1965, Volume: 66, Issue:6

    Topics: Aminopyrine; Animals; Benzoates; Benzopyrenes; Carbon Monoxide; Chlordan; Haplorhini; Hexobarbital; In Vitro Techniques; Liver; Microsomes; NADP; Oils; Organ Size; Zoxazolamine

1965
Stimulation of hepatic microsomal drug-metabolizing enyme systems in primtes byDDT.
    Gastroenterology, 1966, Volume: 51, Issue:2

    Topics: Aminopyrine; Animals; Benzoates; Benzopyrenes; DDT; Haplorhini; Hexobarbital; In Vitro Techniques; Liver; NADP; Zoxazolamine

1966
The effect of o,p'DDD on cortisol and hexobarbital metabolism.
    Biochemical pharmacology, 1966, Volume: 15, Issue:5

    Topics: Animals; Antineoplastic Agents; Carbon Isotopes; Chromatography; Dichlorodiphenyldichloroethane; Hexobarbital; Hydrocortisone; Liver; Male; Microsomes; NADP; Proadifen; Rats

1966
Effects of starvation and refeeding on the oxidation of drugs by liver microsomes.
    Biochemical pharmacology, 1967, Volume: 16, Issue:5

    Topics: Aminopyrine; Aniline Compounds; Animals; Diet; Electron Transport Complex IV; Female; Hexobarbital; Liver; Microsomes; NADP; Organ Size; Pigments, Biological; Rats; Starvation; Sucrose

1967
Spectral studies of drug interaction with hepatic microsomal cytochrome.
    Molecular pharmacology, 1967, Volume: 3, Issue:2

    Topics: Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Hexobarbital; In Vitro Techniques; Kinetics; Liver; Microsomes; NADP; Oxidoreductases; Rats; Spectrophotometry

1967
Further studies on the metabolism of drugs by subfractions of hepatic microsomes. 3. Effects of the NADPH-generating system.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Buffers; Citrates; Enzyme Induction; Glucosephosphate Dehydrogenase; Hexobarbital; Hexosephosphates; Isocitrate Dehydrogenase; Liver; Male; Microsomes; Mixed Function Oxygenases; NADP; Niacinamide; Rabbits

1967
Effect of drug substrates on the reduction of hepatic microsomal cytochrome P-450 by NADPH.
    Biochemical and biophysical research communications, 1968, May-23, Volume: 31, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; Kinetics; Liver; Male; Microsomes; Morphine; NADP; Niacinamide; Oxidation-Reduction; Pigments, Biological; Proadifen; Rats; Sex Factors; Spectrophotometry; Transferases

1968
On the mechanism of the sleep-prolonging effect of antimetabolites of nicotinamide.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 259, Issue:2

    Topics: Anesthesia; Animals; Antimetabolites; Brain; Central Nervous System; Glucosephosphate Dehydrogenase; Hexobarbital; Malate Dehydrogenase; NADP; Niacinamide; Paralysis; Pentosephosphates; Pyridines; Rats; Sleep

1968
Inhibition of cortisol metabolism in vitro by 2-methylnaphthoquinone (menadione): a possible interpretation of the potentiation of cortisol activity in vivo.
    Experientia, 1968, Sep-15, Volume: 24, Issue:9

    Topics: Animals; Drug Synergism; Female; Hexobarbital; Hydrocortisone; Liver; Male; Microsomes; NADP; Rats; Sleep; Vitamin K

1968
Metabolism of drugs in old rats. I. Activities of NADPH-linked electron transport and drug-metabolizing enzyme systems in liver microsomes of old rats.
    Japanese journal of pharmacology, 1968, Volume: 18, Issue:4

    Topics: Aging; Aminobenzoates; Aminopyrine; Aniline Compounds; Animals; Azo Compounds; Benzoates; Body Weight; Cytochromes; Electron Transport; Female; Hexobarbital; Liver; Male; Microsomes; NADP; Organ Size; Oxidation-Reduction; Oxidoreductases; Proteins; Rats; Sex Factors; Strychnine

1968
Studies on the mechanism of sex difference in drug-oxidizing activity of liver microsomes.
    Japanese journal of pharmacology, 1968, Volume: 18, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Electron Transport; Electron Transport Complex IV; Female; Hexobarbital; Liver; Male; Mice; Microsomes; NADP; Oxidation-Reduction; Oxidoreductases; Rabbits; Rats; Sex Factors

1968
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.
    Molecular pharmacology, 1969, Volume: 5, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Sex Factors; Spectrophotometry; Time Factors; Valerates

1969
Studies on the relationship between the effects of various substances on absorption spectrum of cytochrome P-450 and the reduction of p-nitrobenzoate by mouse liver microsomes.
    Molecular pharmacology, 1969, Volume: 5, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzoates; Carbon Monoxide; Cytochromes; Ethylamines; Hexobarbital; Imidazoles; In Vitro Techniques; Kinetics; Liver; Male; Mice; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Proadifen; Pyridines; Spectrophotometry

1969
Metabolism and cytochrome P-450 binding spectra of (+)- and (-)-hexobarbital in rat liver microsomes.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1969, Volume: 350, Issue:5

    Topics: Animals; Cytochromes; Hexobarbital; Kinetics; Liver; Male; Microsomes; NADP; Phenobarbital; Rats; Spectrophotometry; Stereoisomerism

1969
Effect of vitamin C deficiency on the metabolism of drugs and NADPH-linked electron transport system in liver microsomes.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Aminopyrine; Aniline Compounds; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Diphenhydramine; Electron Transport; Guinea Pigs; Hexobarbital; Kidney; Liver; Male; Meperidine; Microsomes; NAD; NADP; Nitrobenzenes; Nitrophenols; Organ Size; p-Dimethylaminoazobenzene; Time Factors; Zoxazolamine

1969
Species differences in the alteration of drug-metabolizing activities of liver microsomes by thyroxine treatment.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Aminopyrine; Aniline Compounds; Animals; Body Weight; Electron Transport; Female; Heart; Hexobarbital; In Vitro Techniques; Liver; Male; Mice; Microsomes; NADP; Nitrobenzenes; Organ Size; Oxidoreductases; Rabbits; Rats; Species Specificity; Thyroxine

1969
The inhibitory effect of aureomycin (chlortetracycline) pretreatment on some rat liver microsomal enzyme activities.
    Biochemical pharmacology, 1969, Volume: 18, Issue:6

    Topics: Albumins; Aminopyrine; Animals; Body Weight; Chlortetracycline; Cytochromes; Depression, Chemical; Hexobarbital; Injections, Intraperitoneal; Liver; Magnesium; Male; Microsomes; NADP; Organ Size; Phenobarbital; Proteins; Rats; Sleep

1969
Hydroxylation of benzphetamine and other drugs by a solubilized form of cytochrome P-450 from liver microsomes: lipid requirement for drug demethylation.
    Biochemical and biophysical research communications, 1969, Aug-15, Volume: 36, Issue:4

    Topics: Aminopyrine; Animals; Appetite Depressants; Benzphetamine; Cytochromes; Depression, Chemical; Ethers; Fatty Acids; Formaldehyde; Hexobarbital; Lipid Metabolism; Liver; Microsomes; Mixed Function Oxygenases; Morphinans; NADP; Oxidoreductases; Phenethylamines; Phenobarbital; Propylamines; Rabbits; Spectrophotometry

1969
Disulfiram impairment of drug metabolism by rat liver microsomes.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 170, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Cytochromes; Disulfiram; Heme; Hexobarbital; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Protein Binding; Rats; Sleep; Spectrum Analysis; Thiocarbamates

1969
Effects of metyrapone on liver microsomal drug oxidations.
    Molecular pharmacology, 1969, Volume: 5, Issue:1

    Topics: Acetanilides; Aminopyrine; Animals; Depression, Chemical; Hexobarbital; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Morphine; NADP; Phenobarbital; Rats; Sleep; Stimulation, Chemical; Trichloroethylene; Tyramine

1969
Characteristics of guinea pig liver and adrenal monooxygenase systems.
    Molecular pharmacology, 1970, Volume: 6, Issue:3

    Topics: Adrenal Glands; Aminopyrine; Aniline Compounds; Animals; Binding Sites; Cytochromes; Fatty Acids; Guinea Pigs; Hexobarbital; Hydrocortisone; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Spectrum Analysis; Succinates; Vitamin K

1970
Hepatic drug-metabolizing enzyme activity in rats pretreated with (-)-emetine or (plus or minus)-2,3-dehydroemetine.
    The Biochemical journal, 1970, Volume: 117, Issue:3

    Topics: Aminopyrine; Animals; Depression, Chemical; Drug Synergism; Emetine; Female; Glucosephosphate Dehydrogenase; Hexobarbital; Liver; Microsomes, Liver; NADP; Phenobarbital; Rats; Sulfonamides

1970
Enzymatic basis of cyclophosphamide activation by hepatic microsomes of the rat.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 174, Issue:2

    Topics: Animals; Benzoates; Cyclophosphamide; Cytochromes; Female; Glucose-6-Phosphatase; Hexobarbital; Hydrocortisone; Male; Microsomes, Liver; NADP; Nitrophenols; Oxidoreductases; Phenobarbital; Rats; Sex Factors; Testosterone

1970
Interaction of mixed function oxidase with its substrates and associated redox transitions of cytochrome P-450 and pyridine nucleotides in perfused rat liver.
    European journal of biochemistry, 1970, Volume: 15, Issue:3

    Topics: Animals; Cytochromes; Endoplasmic Reticulum; Fluorescence; Hexobarbital; Lactates; Liver; Male; Metyrapone; Microsomes, Liver; NAD; NADP; Oxidoreductases; Oxygen Consumption; Perfusion; Phenobarbital; Pyruvates; Rats; Spectrophotometry

1970
Effects of morphine treatment and starvation on the substrate interaction with P-450 in the oxidation of drugs by liver microsomes.
    Japanese journal of pharmacology, 1970, Volume: 20, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Blood Proteins; Castration; Chemical Phenomena; Chemistry; Depression, Chemical; Electron Transport; Female; Hexobarbital; In Vitro Techniques; Kinetics; Male; Methyltestosterone; Microsomes, Liver; Morphine; NADP; Oxidation-Reduction; Oxidoreductases; Pigments, Biological; Rats; Spectrophotometry; Starvation; Stimulation, Chemical; Testosterone; Zoxazolamine

1970
The presence of a monooxygenase system in human fetal liver microsomes.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1970, Oct-22, Volume: 9, Issue:20

    Topics: Aminopyrine; Aniline Compounds; Carbon Isotopes; Cytochromes; Electron Transport; Fatty Acids; Fetus; Hexobarbital; Humans; In Vitro Techniques; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygenases; Spectrophotometry; Testosterone

1970
Induction of hepatic drug metabolism in rats by methylchloroform inhalation.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Aminopyrine; Animals; Chloroform; Cycloheximide; Cytochromes; Dactinomycin; Enzyme Induction; Hexobarbital; In Vitro Techniques; Liver; Male; Meprobamate; Microsomes, Liver; Morphine; NADP; Protein Binding; Rats; Reflex; Zoxazolamine

1970
Effect of various inducers on electron transport system associated with drug metabolism by liver microsomes.
    Metabolism: clinical and experimental, 1971, Volume: 20, Issue:2

    Topics: Animals; Cytochromes; Electron Transport; Female; Hexobarbital; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Morpholines; NADP; Oxidation-Reduction; Oxidoreductases; Pharmaceutical Preparations; Phenobarbital; Rats; Spironolactone; Stimulation, Chemical

1971
A new spectral intermediate associated with cytochrome P-450 function in liver microsomes.
    Biochemical and biophysical research communications, 1971, Jan-08, Volume: 42, Issue:1

    Topics: Animals; Cytochromes; Hexobarbital; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Rats; Spectrophotometry

1971
The influence of magnesium and some other divalent cations on hepatic microsomal drug metabolism in vitro.
    Biochemical pharmacology, 1970, Volume: 19, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Calcium; Chlorides; Cobalt; Copper; Cytochromes; Edetic Acid; Hexobarbital; In Vitro Techniques; Iron; Magnesium; Male; Manganese; Microsomes, Liver; NADP; Nitrophenols; Phenobarbital; Potassium; Rats; Strontium; Sulfates; Zinc; Zoxazolamine

1970
New aspect of guinea pig liver 17-beta-hydroxysteroid (testosterone) dehydrogenase.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Apr-22, Volume: 10, Issue:8

    Topics: Animals; Chemical Precipitation; Chromatography, DEAE-Cellulose; Electrophoresis, Disc; Guinea Pigs; Hexobarbital; Hydroxysteroid Dehydrogenases; Liver; NAD; NADP; Oxidoreductases; Quaternary Ammonium Compounds; Spectrophotometry; Sulfates; Testosterone

1971
Human liver microsomal drug metabolism.
    Biochemical pharmacology, 1970, Volume: 19, Issue:4

    Topics: Aged; Aniline Compounds; Codeine; Cytochromes; Enzyme Induction; Female; Hexobarbital; Humans; Male; Microsomes, Liver; Middle Aged; NADP; Oxidation-Reduction; Oxidoreductases; Spectrophotometry; Sulfites

1970
Studies on the regulation of the activity of drug oxidation in rat liver microsomes by androgen and estrogen.
    Biochemical pharmacology, 1970, Volume: 19, Issue:5

    Topics: Aminopyrine; Androgens; Animals; Castration; Cytochromes; Dealkylation; Diethylstilbestrol; Estradiol; Estrogens; Female; Hexobarbital; Kinetics; Male; Metabolism; Methylation; Methyltestosterone; Microsomes, Liver; Mixed Function Oxygenases; Muscles; NADP; Organ Size; Oxidoreductases; Protein Binding; Proteins; Rats; Seminal Vesicles; Spectrophotometry; Stimulation, Chemical; Testosterone; Tetrazolium Salts

1970
The effect of thiamine consumption on liver microsomal drug-metabolizing pathways.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 176, Issue:3

    Topics: Aminopyrine; Aniline Compounds; Animals; Body Weight; Cytochromes; Diet; Esterases; Female; Glucosephosphate Dehydrogenase; Hexobarbital; Kinetics; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Organ Size; Oxidoreductases; Paralysis; Pharmaceutical Preparations; Phosphogluconate Dehydrogenase; Rats; Sex Factors; Sleep; Thiamine; Thiamine Deficiency; Zoxazolamine

1971
Effect of carbon tetrachloride induced progressive liver damage on drug-metabolizing enzymes and cytochrome P-450 in rat liver.
    Acta pharmacologica et toxicologica, 1971, Volume: 29, Issue:5

    Topics: Aniline Compounds; Animals; Body Weight; Carbon Tetrachloride; Cytochromes; Glucosephosphate Dehydrogenase; Hexobarbital; Liver; Liver Cirrhosis; NADP; Nitrophenols; Oxidoreductases; Rats; Time Factors

1971
Drug metabolism by an acetone powder from rat hepatic microsomes.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, Sep-15, Volume: 10, Issue:18

    Topics: Acetone; Aminopyrine; Animals; Benzoates; Female; Glucosephosphate Dehydrogenase; Hexobarbital; Male; Methylation; Microsomes, Liver; NADP; Nitrophenols; Oxidation-Reduction; Rats; Sex Factors; Transferases

1971
Studies of the stoichiometric relationships between the oxidation of drugs and the oxidation of reduced pyridine nucleotides by liver microsomal enzymes.
    Chemico-biological interactions, 1971, Volume: 3, Issue:4

    Topics: Adenine Nucleotides; Aminopyrine; Cytochromes; Hexobarbital; Imipramine; Microsomes, Liver; Morphinans; NADP; Nucleotides; Oxidation-Reduction; Pharmaceutical Preparations; Pyridines

1971
The state of NADPH-NADP + during mixed-function oxidation of hexobarbital in hemoglobin-free perfused rat liver.
    Chemico-biological interactions, 1971, Volume: 3, Issue:4

    Topics: Animals; Fluorometry; Hemoglobins; Hexobarbital; Liver; Mitochondria, Liver; NADP; Oxidation-Reduction; Oxidoreductases; Perfusion; Phenobarbital; Rats

1971
Molecular aspects of drug metabolism.
    Acta pharmacologica et toxicologica, 1971, Volume: 29 Suppl 3

    Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Drug Interactions; Electron Transport; Fats; Hexobarbital; Hydroxylation; Lipids; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Pharmaceutical Preparations; Rats; Solubility; Spectrophotometry; Steroids; Testosterone; Triamcinolone

1971
Interactions of spironolactone with hepatic microsomal drug-metabolizing enzyme systems.
    Biochemical pharmacology, 1971, Volume: 20, Issue:8

    Topics: Animals; Cytochromes; Dealkylation; Drug Antagonism; Electron Transport; Enzyme Induction; Hexobarbital; In Vitro Techniques; Male; Mice; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Sleep; Spironolactone

1971
A study of some possible mechanisms by which glucose inhibits drug metabolism in vivo and in vitro.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 180, Issue:1

    Topics: Animals; Barbiturates; Benzphetamine; Brain Chemistry; Carbon Isotopes; Electron Transport Complex IV; Glucose; Glucosephosphate Dehydrogenase; Hexobarbital; Kinetics; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; NADP; Organ Size; Oxidoreductases; Pentobarbital; Sleep

1972
An approach measurement of the stoichiometric relationship between hepatic microsomal drug metabolism and the oxidation of reduced nicotinamide adenine dinucleotide phosphate.
    Molecular pharmacology, 1972, Volume: 8, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Benzyl Compounds; Chlorine; Dealkylation; Ethylamines; Hexobarbital; Imipramine; Male; Methylamines; Microsomes, Liver; Morphine; NADP; Oxidation-Reduction; Pharmaceutical Preparations; Rats

1972
A study of the interaction of a series of substituted barbituric acids with the hepatic microsomal monooxygenase.
    Archives of biochemistry and biophysics, 1972, Volume: 151, Issue:2

    Topics: Amobarbital; Animals; Barbiturates; Cytochromes; Hexobarbital; Hydrogen-Ion Concentration; Lipids; Male; Microsomes, Liver; NAD; NADP; Oxygenases; Pentobarbital; Phenobarbital; Rats; Secobarbital; Solubility; Spectrophotometry

1972
Effect of halothane on the hepatic drug metabolizing system.
    Naunyn-Schmiedeberg's archives of pharmacology, 1972, Volume: 273, Issue:4

    Topics: Animals; Cytochromes; Female; Halothane; Hexobarbital; Liver; NADP; Organ Size; Oxidoreductases; Oxygen; Rats; Rats, Inbred Strains; Sleep

1972
Effect of cold exposure on drug action and hepatic drug metabolism in the rat.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:1

    Topics: Adrenal Glands; Aminopyrine; Animals; Ascorbic Acid; Barbiturates; Carbon Isotopes; Cold Temperature; Cytochrome c Group; Cytochrome P-450 Enzyme System; Glycine; Hexobarbital; Kinetics; Liver; Male; Meprobamate; Microsomes, Liver; NADP; Oxidoreductases; Protein Biosynthesis; Rats

1972
[Tolerance of barbiturates in patients with viral hepatitis].
    Minerva medica, 1972, Oct-27, Volume: 63, Issue:76

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Bilirubin; Cytochrome P-450 Enzyme System; Drug Tolerance; Hepatitis A; Hexobarbital; Humans; Injections, Intravenous; Liver; Middle Aged; NADP; Oxidoreductases

1972
Interactions of digitoxigenin and digoxigenin with cytochrome P-450.
    Research communications in chemical pathology and pharmacology, 1972, Volume: 4, Issue:3

    Topics: Animals; Cardanolides; Cytochrome c Group; Drug Interactions; Hexobarbital; In Vitro Techniques; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Rats; Spectrophotometry; Testosterone

1972
Kinetic parameters of drug-metabolizing enzymes in Ca 2+ -sedimented microsomes from rat liver.
    Biochemical pharmacology, 1972, Dec-15, Volume: 21, Issue:24

    Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Calcium; Cell Fractionation; Centrifugation, Density Gradient; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Dealkylation; Hexobarbital; Kinetics; Male; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Rats; Spectrophotometry; Sucrose; Ultracentrifugation

1972
Investigation of the effects of methyltestosterone, cortisone and spironolactone on the hepatic microsomal mixed function oxidase system in male and female rats.
    Biochemical pharmacology, 1973, Feb-01, Volume: 22, Issue:3

    Topics: Animals; Cortisone; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Female; Hexobarbital; Kinetics; Male; Methyltestosterone; Microsomes, Liver; Morphinans; NADP; Organ Size; Oxidoreductases; Protein Binding; Rats; Seminal Vesicles; Sex Factors; Spironolactone; Time Factors; Uterus

1973
Effect of 2,4-dinitrophenol on the oxidative metabolism of hexobarbital by cytochrome P-450 in perfused rat liver.
    Journal of biochemistry, 1983, Volume: 94, Issue:2

    Topics: 2,4-Dinitrophenol; Animals; Cytochrome P-450 Enzyme System; Dinitrophenols; Hexobarbital; Liver; Male; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Perfusion; Rats; Rats, Inbred Strains

1983
Stoichiometric cooperation of NADPH and hexobarbital in hepatic microsomes during the catalysis of hydrogen peroxide formation.
    Archives of biochemistry and biophysics, 1982, Volume: 216, Issue:2

    Topics: Animals; Hexobarbital; Hydrogen Peroxide; Kinetics; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rabbits

1982
Modulation of drug metabolism by food restriction in male rats.
    Biochemical and biophysical research communications, 1982, Feb-11, Volume: 104, Issue:3

    Topics: Animals; Body Weight; Cytochrome P-450 Enzyme System; Food Deprivation; Guanosine Diphosphate; Hexobarbital; Malate Dehydrogenase; Male; Microsomes, Liver; NADP; Organ Size; Rats; Sleep

1982
Oxidation-reduction states of pyridine nucleotide and cytochrome P-450 during mixed-function oxidation in perfused rat liver.
    The Journal of biological chemistry, 1981, Dec-25, Volume: 256, Issue:24

    Topics: Aminopyrine; Animals; Cytochrome P-450 Enzyme System; Hexobarbital; Kinetics; Liver; Male; Mixed Function Oxygenases; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Perfusion; Phenobarbital; Rats; Rats, Inbred Strains

1981
Damages in the microsomal drug metabolizing enzyme system after partial x-irradiation of rat liver.
    Radiation research, 1974, Volume: 58, Issue:1

    Topics: Animals; Cytochrome P-450 Enzyme System; Electron Transport; Hexobarbital; Hydroxylation; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Phosphoric Monoester Hydrolases; Rats; Rats, Wistar; X-Rays

1974
[EFFECT OF SOME RADIO-PROTECTIVE AGENTS ON THE ENZYME SYSTEM OF LIVER MICROSOMES DEGRADING HEXOBARBITAL].
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Cystamine; Cysteamine; Glucosephosphate Dehydrogenase; Hexobarbital; Hexosephosphates; Histamine; Liver; Metabolism; Microsomes, Liver; NADP; Pharmacology; Radiation-Protective Agents; Rats; Research; Serotonin

1964
METABOLISM OF DRUGS. XL. ENZYMATIC OXIDATION OF METHYLHEXABITAL. 3. PURIFICATION AND PROPERTIES OF 3-HYDROXY-METHYLHEXABITAL DEHYDROGENASE.
    Journal of biochemistry, 1964, Volume: 55

    Topics: Alcohol Oxidoreductases; Animals; Chromatography; Hexobarbital; Liver; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Rabbits; Research

1964
THE EFFECTS OF NOREPINEPHRINE TREATMENT ON DRUG METABOLISM BY LIVER MICROSOMES FROM RATS.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Aminopyrine; Aniline Compounds; Carbohydrate Metabolism; Ergotamine; Glucosephosphate Dehydrogenase; Hexobarbital; Isoproterenol; Liver; Liver Glycogen; Metabolism; Microsomes; Microsomes, Liver; NADP; Norepinephrine; Pharmacology; Phenoxybenzamine; Rats; Research

1964
KINETICS OF DRUG METABOLISM BY HEPATIC MICROSOMES.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Acetanilides; Chlorpromazine; Hexobarbital; Kinetics; Liver; Metabolism; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Morphine; NADP; Oxidoreductases; Pharmacology; Phenobarbital; Phenylbutazone; Rats; Research; Zoxazolamine

1964
VARIATION IN THE ACTIVITY OF LIVER MICROSOMAL DRUG-METABOLIZING ENZYMES IN RATS IN RELATION TO THE AGE.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Aging; Animals, Newborn; Carisoprodol; Diphosphates; Hexobarbital; Insecticides; Liver; Meprobamate; Metabolism; Microsomes; NADP; Oxidoreductases; Pentobarbital; Pharmacology; Rats; Research; Seizures; Strychnine; Toxicology

1964
Rabbit 3-hydroxyhexobarbital dehydrogenase is a NADPH-preferring reductase with broad substrate specificity for ketosteroids, prostaglandin D₂, and other endogenous and xenobiotic carbonyl compounds.
    Biochemical pharmacology, 2013, Nov-01, Volume: 86, Issue:9

    Topics: 17-Ketosteroids; Alcohol Oxidoreductases; Aldehydes; Amino Acid Sequence; Animals; Cattle; Cloning, Molecular; Enzyme Inhibitors; Hexobarbital; Hydrogen-Ion Concentration; Isatin; Ketones; Ketosteroids; Molecular Sequence Data; NADP; Phenolphthalein; Prostaglandin D2; Rabbits; Substrate Specificity; Xenobiotics

2013