hexobarbital has been researched along with metyrapone in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (88.89) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Klinger, W; Muller, D | 1 |
| Lyakhovich, V; Mishin, V; Pokrovsky, A | 1 |
| Capdevila, J; Moldéus, P; Orrenius, S; Vadi, H | 1 |
| Cooper, DY; Rosenthal, O; Schleyer, H; Thomas, JH; Vars, HM | 1 |
| Daniel, W; Netter, KJ | 1 |
| Franklin, MR | 1 |
| Rösen, P; Stier, A | 1 |
| Illing, HP; Netter, KJ | 1 |
| Leibman, KC | 1 |
| Brauser, B; Sies, H | 1 |
| Archakov, AI; Kretovich, WL; Melik-Sarkissian, SS; Raikchinstein, MV | 1 |
| Archakov, AI; Kretovich, VL; Melik-Sarkisian, SS; Raĭkhinshteĭn, MV | 2 |
| Feuer, G; Lumb, G; Moddel, G; Sosa-Lucero, JC | 1 |
| Hildebrandt, AG | 1 |
| Casida, JE; Engel, JL; Matthews, HB; Skrinjarić-Spoljar, M | 1 |
| Estabrook, RW; Hildebrandt, AG; Leibman, KC | 1 |
18 other study(ies) available for hexobarbital and metyrapone
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developmental aspects of xenobiotic transformation.
Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Ethylmorphine; Female; Glucosephosphates; Hexobarbital; Hydrogen-Ion Concentration; Metyrapone; Microsomes, Liver; NAD; NADP; Niacinamide; Oxidoreductases, N-Demethylating; Oxidoreductases, O-Demethylating; Phenobarbital; Pregnancy; Rats; Semicarbazides | 1976 |
Relationship between the reduction of oxygen, artificial acceptors and cytochrome P-450 by NADPH--cytochrome c reductase.
Topics: 2,6-Dichloroindophenol; Animals; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Epinephrine; Hexobarbital; Hydroxybenzoates; In Vitro Techniques; Kinetics; Male; Metyrapone; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxygen Consumption; Rats | 1977 |
The metabolism of benzo(alpha)pyrene in isolated rat liver cells.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Binding Sites; Cells, Cultured; Flavonoids; Hexobarbital; Kinetics; Liver; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Proadifen; Rats; Rotenone; Solubility; Stimulation, Chemical | 1975 |
Comparison of the induction course, biophysical chemical interactions and photochemical action spectra of phenobarbital and 3-methylcholanthrene induce hepatic microsomal P-450.
Topics: Aniline Compounds; Animals; Biotransformation; Body Weight; Carbon Monoxide; Codeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Hexobarbital; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital; Photochemistry; Polycyclic Compounds; Proadifen; Rats; Spectrum Analysis; Time Factors | 1975 |
Alteration of cytochrome P-450 by prolonged administration of imipramine and/or lithium to rats.
Topics: Animals; Carbamazepine; Cytochrome P-450 Enzyme System; Desipramine; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Hexobarbital; Imipramine; Isoenzymes; Lithium; Liver; Male; Metyrapone; Rats; Rats, Inbred Strains | 1990 |
Piperonyl butoxide metabolism by cytochrome P-450: factors affecting the formation and disappearance of the metabolite-cytochrome P-450 complex.
Topics: Animals; Cysteamine; Cytochrome P-450 Enzyme System; Dioxoles; Glucuronates; Hexobarbital; Kinetics; Male; Metyrapone; Mice; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Pesticide Synergists; Piperonyl Butoxide; Protein Binding; Rats; S-Adenosylmethionine; Spectrophotometry; Uridine Diphosphate Sugars | 1972 |
Proceedings: Kinetics of the binding of carbon monoxide and oxygen to microsomal cytochrome P450 and the influence of substrates.
Topics: Animals; Binding Sites; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Halothane; Hexobarbital; In Vitro Techniques; Kinetics; Ligands; Metyrapone; Microsomes, Liver; Oxygen Consumption; Phenobarbital; Photolysis; Rats; Spectrophotometry; Temperature; Tetrachloroethylene; Trichloroethylene | 1974 |
Kinetic experiments on the synergistic effect of NADH on microsomal drug oxidation.
Topics: Aniline Compounds; Animals; Anisoles; Carbon Monoxide; Chloromercuribenzoates; Drug Synergism; Hexobarbital; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NAD; Nitro Compounds; Oxidation-Reduction; Oxygen Consumption; Pharmaceutical Preparations; Pharmacology; Phenobarbital; Phenols; Proadifen; Pyridines; Rats; Spectrophotometry | 1974 |
Effects of metyrapone on liver microsomal drug oxidations.
Topics: Acetanilides; Aminopyrine; Animals; Depression, Chemical; Hexobarbital; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Morphine; NADP; Phenobarbital; Rats; Sleep; Stimulation, Chemical; Trichloroethylene; Tyramine | 1969 |
Interaction of mixed function oxidase with its substrates and associated redox transitions of cytochrome P-450 and pyridine nucleotides in perfused rat liver.
Topics: Animals; Cytochromes; Endoplasmic Reticulum; Fluorescence; Hexobarbital; Lactates; Liver; Male; Metyrapone; Microsomes, Liver; NAD; NADP; Oxidoreductases; Oxygen Consumption; Perfusion; Phenobarbital; Pyruvates; Rats; Spectrophotometry | 1970 |
The binding of microsomal hydroxylation substrates to cytochrome P-450Rh and its effect on the nitrogen fixation by lupin bacteroids.
Topics: Aniline Compounds; Binding Sites; Camphor; Cytochrome P-450 Enzyme System; Hexobarbital; Hydrogen-Ion Concentration; Metyrapone; Microsomes; Nitrogen Fixation; Plants; Proadifen; Protein Binding; Rhizobium; Spectrophotometry; Spectrophotometry, Ultraviolet; Ultracentrifugation | 1974 |
[Spectral properties of cytochrome P-450 from lupin nodule bacteroids].
Topics: Aniline Compounds; Animals; Camphor; Cytochrome P-450 Enzyme System; Hexobarbital; Metyrapone; Microsomes, Liver; Proadifen; Rats; Rhizobium; Spectrophotometry | 1974 |
[Effect of substrates and microsomal hydroxylation inhibitors on the nitrogen-fixing activity of lupin bacteroids].
Topics: Aniline Compounds; Camphor; Cytochrome P-450 Enzyme Inhibitors; Hexobarbital; Metyrapone; Nitrogen Fixation; Oxygen Consumption; Proadifen; Rhizobium | 1974 |
Failure of various drugs to induce drug-metabolizing enzymes in extrahepatic tissues of the rat.
Topics: Adrenal Glands; Aminopyrine; Aniline Compounds; Animals; Brain; Chlorpromazine; Coumarins; Enzyme Induction; Female; Hexobarbital; Hydrochlorothiazide; Intestines; Kidney; Liver; Male; Methylcholanthrene; Metyrapone; Mixed Function Oxygenases; Organ Size; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors | 1971 |
The binding of metyrapone to cytochrome P-450 and its inhibitory action on liver microsomal mixed-function oxidase reactions.
Topics: Acetanilides; Aminopyrine; Animals; Binding Sites; Codeine; Cytochromes; Hexobarbital; Metyrapone; Microsomes, Liver; Morphinans; Nitrophenols; Oxidation-Reduction; Rats; Spectrum Analysis | 1971 |
Response of hepatic microsomal mixed-function oxidases to various types of insecticide chemical synergists administered to mice.
Topics: Alkynes; Aniline Compounds; Animals; Anisoles; Benzopyrans; Carbamates; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Dimethyl Sulfoxide; Dioxoles; Drug Synergism; Enzyme Induction; Ethers; Hexobarbital; Hydrocarbons, Halogenated; Hydroxylation; In Vitro Techniques; Indoles; Insecticides; Male; Metyrapone; Mice; Microsomes, Liver; Mixed Function Oxygenases; Nitro Compounds; Nitrophenols; Organophosphorus Compounds; Organothiophosphorus Compounds; Oxidoreductases; Pesticide Synergists; Pesticides; Piperonyl Butoxide; Proadifen; Pyrazoles; Rotenone; Sleep; Spectrophotometry; Sulfites; Thiadiazoles; Time Factors | 1971 |
Spectrophotometric studies of interactions between various substrates in their binding to microsomal cytochrome P-450.
Topics: Aniline Compounds; Animals; Cytochromes; Hexobarbital; Kinetics; Liver; Metyrapone; Rats; Solvents; Spectrophotometry | 1969 |