hexobarbital has been researched along with methadone in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Buchholz, J; Fraser, IM; Strother, A | 1 |
| Komthong, S; Thithapandha, A; Yoovathaworn, K | 1 |
| Burke, DH; Mann, DE | 1 |
| Alvares, AP; Kappas, A | 1 |
| JACOB, J; MICHAUD, G | 1 |
9 other study(ies) available for hexobarbital and methadone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effect of glucose administration on various rat hepatic constituents and on the spectral binding of hexobarbital and methadone to rat hepatic cytochrome P450.
Topics: Animals; Cholesterol; Cytochrome P-450 Enzyme System; Glucose; Hexobarbital; Lipid Metabolism; Liver; Liver Glycogen; Male; Methadone; Microsomes, Liver; Pentobarbital; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Rats, Inbred Strains | 1989 |
Biphasic effect of methadone on hepatic drug metabolism.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Biotransformation; Dose-Response Relationship, Drug; Enzyme Induction; Hexobarbital; Liver; Male; Metabolic Clearance Rate; Methadone; Mice; Microsomes, Liver; Mixed Function Oxygenases; Puromycin; Sleep; Time Factors; Zoxazolamine | 1987 |
Thiazine dye antagonism of opioid lethality in mice.
Topics: Animals; Codeine; Dextropropoxyphene; Drug Synergism; Hexobarbital; Lethal Dose 50; Levorphanol; Male; Meperidine; Methadone; Methylene Blue; Mice; Morphinans; Morphine; Sleep; Thiazines; Time Factors; Tolonium Chloride | 1974 |
Influence of phenobarbital on the metabolism and analgesic effect of methadone in rats.
Topics: Analgesia; Animals; Biotransformation; Estradiol; Hexobarbital; Hydrocarbons; Kinetics; Male; Methadone; Microsomes, Liver; Morphinans; Phenobarbital; Rats; Testosterone | 1972 |
[The effect of various pharmacological agents (amphetamine, cocaine, caffeine, hexobarbital, meprobamate, morphine, dextromoramide, 1-methadone, pethidine and CT 3570) on the time of exhaustion and behavior of animals swimming at 20 degrees C].
Topics: Amphetamine; Amphetamines; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior; Caffeine; Central Nervous System Stimulants; Cocaine; Dextromoramide; Hexobarbital; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine; Physical Exertion; Swimming; Tomography, X-Ray Computed | 1960 |