hexobarbital and hydantoins

hexobarbital has been researched along with hydantoins in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Francis, KT; Hamrick, ME1
Kato, R; Murayama, N; Yamazoe, Y; Yasumori, T1
Dubey, RK; Guengerich, FP; Knodell, RG; Wilkinson, GR1
Jenner, P; Testa, B1
Mandel, HG; Riis, M1
Carpenter, JE; Castellion, AW; Ellis, KO; Halliday, RP; Honkomp, LJ; Wessels, FL1
Krimsley, V; Shaffer, JW; Steinberg, E; Winstead, WB1
CASHIN, CH; OLDFIELD, W1

Reviews

1 review(s) available for hexobarbital and hydantoins

ArticleYear
The influence of stereochemical factors on drug disposition.
    Drug metabolism reviews, 1973, Volume: 2, Issue:2

    Topics: Alcohols; Amphetamine; Analgesics; Animals; Barbiturates; Dealkylation; Deamination; Dextroamphetamine; Dihydroxyphenylalanine; Ephedrine; Guinea Pigs; Haplorhini; Hexobarbital; Humans; Hydantoins; Hydroxylation; Ketones; Male; Methamphetamine; Mice; Oxidation-Reduction; Pharmaceutical Preparations; Rabbits; Rats; Species Specificity; Stereoisomerism; Structure-Activity Relationship; Succinimides; Warfarin

1973

Other Studies

7 other study(ies) available for hexobarbital and hydantoins

ArticleYear
Dantrolene inhibition of the hepatic mixed function oxidase system.
    Research communications in chemical pathology and pharmacology, 1979, Volume: 23, Issue:1

    Topics: Aminopyrine N-Demethylase; Animals; Cytochrome P-450 Enzyme System; Dantrolene; Ethylmorphine-N-Demethylase; Hexobarbital; Hydantoins; Kinetics; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Time Factors

1979
Polymorphism in hydroxylation of mephenytoin and hexobarbital stereoisomers in relation to hepatic P-450 human-2.
    Clinical pharmacology and therapeutics, 1990, Volume: 47, Issue:3

    Topics: Cytochrome P-450 Enzyme System; Hexobarbital; Humans; Hydantoins; Hydroxylation; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; Phenotype; Polymorphism, Genetic; Stereoisomerism

1990
Oxidative metabolism of hexobarbital in human liver: relationship to polymorphic S-mephenytoin 4-hydroxylation.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:3

    Topics: Cytochrome P-450 Enzyme System; Hexobarbital; Humans; Hydantoins; Hydroxylation; In Vitro Techniques; Liver; Male; Mephenytoin; Oxidation-Reduction; Polymorphism, Genetic

1988
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea

1970
Dantrolene, a direct acting skeletal muscle relaxant.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:6

    Topics: Animals; Blood Pressure; Cats; Cholinesterase Inhibitors; Dantrolene; Decamethonium Compounds; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hexobarbital; Hydantoins; Male; Mice; Muscle Contraction; Muscle Relaxants, Central; Paraldehyde; Physostigmine; Rats; Reflex; Sleep; Time Factors; Tubocurarine

1973
Substitution in the hydantoin ring. VII. N-3-Propionic acid and its ethyl ester and N-3-(2-cyanoethyl) derivatives.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:3

    Topics: Alkylation; Animals; Drug Synergism; Electroshock; Hexobarbital; Hydantoins; Infrared Rays; Magnetic Resonance Spectroscopy; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Propionates; Spectrum Analysis; Ultraviolet Rays

1968
THE CHEMISTRY AND PHARMACOLOGY OF A SERIES OF CYCLOALKANESPIRO-5'-HYDANTOINS.
    Journal of medicinal chemistry, 1965, Volume: 8

    Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Anticonvulsants; Antipyretics; Chemistry, Pharmaceutical; Hexobarbital; Hydantoins; Mice; Pharmacology; Research; Spiro Compounds; Toxicology

1965