hexobarbital has been researched along with diazepam in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (63.64) | 18.7374 |
| 1990's | 9 (16.36) | 18.2507 |
| 2000's | 8 (14.55) | 29.6817 |
| 2010's | 3 (5.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Caron, G; Ermondi, G | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| de Angelis, L; Traversa, U; Vertua, R | 2 |
| Lehmann, K; Schmidt, J | 1 |
| Garibova, TL; Klygul', TA; Vikhliaev, IuI | 1 |
| Akatsu, M; Asami, Y; Inaba, S; Kitagawa, S; Otsuka, M; Yamamoto, H | 1 |
| Wenzl, H | 1 |
| Kästner, I | 1 |
| Bjertnaes, LJ | 1 |
| Ghoneim, MT; Mahfouz, M; Makar, AB | 1 |
| Lapin, AA | 1 |
| Beloiartsev, FF; Vladimirov, PV | 1 |
| Holme, I; Lund, I; Thorud, T | 1 |
| Idänpään-Heikkilä, J; Vorne, M | 1 |
| Kästner, I; Ke, HH; Liebmann, H; Wiezorek, WD | 1 |
| Arushanian, EB; Botvev Orkhiĭ, P | 1 |
| Becker, A; Grecksch, G; Matthies, H; Ruethrich, HL; Schneider, R | 1 |
| Böke-Kuhn, K; Knappen, F | 1 |
| Kimishima, K; Ogura, C | 1 |
| Asami, Y; Hirohashi, T; Inaba, S; Otsuka, M; Yamamoto, H | 1 |
| Gogolák, G; Liebeswar, G; Stumpf, C | 1 |
| Haefely, W; Jalfre, M; Monachon, MA | 1 |
| Gillette, JR; Stripp, B | 1 |
| De Souza, NJ; Desai, PD; Dohadwalla, AN; Kohl, H | 1 |
| Boczán, G; Halász, P; Hidasi, J; Velok, G | 1 |
| Moriya, R; Nagawa, Y; Nakajima, R; Saji, Y; Take, Y; Yui, T | 1 |
| Dzhagatspanian, IA; Klygul', TA; Vikhliaev, IuI | 1 |
| Inoki, R; Iwatsubo, K; Shigenaga, Y | 1 |
| Babbini, M; De Marchi, F; Montanaro, N; Strocchi, P; Torrielli, MV | 1 |
| Kuschinsky, G | 1 |
| Katz, MH; Krop, S; Yen, HC | 1 |
| Adronati, SA; Klygul', TA; Prokudin, VN; Vikhliaev, IuI | 1 |
| Clark, R; Lynes, TE; Marvel, JP; Price, WA; Smith, DH; Vernier, VG; Woodward, JK | 1 |
| Klinger, W; Müller, D; Richter, K; Wierzba, W | 1 |
| Zetler, G | 1 |
| Cebula, TA; El-Hage, AN; Ferrans, VJ | 1 |
| Bollkämper, A; Siegers, CP; Younes, M | 1 |
| Bluth, R | 1 |
| Boido, A; Marzano, C; Peana, A; Satta, M; Savelli, F | 1 |
| Carlsson, S; Korkmaz, S; Wahlström, G | 1 |
| Carlsson, S; Wahlström, G | 1 |
| Helton, DR; Kallman, MJ; Monn, JA; Schoepp, DD; Tizzano, JP | 1 |
| Kuribara, H; Maruyama, Y; Stavinoha, WB | 1 |
| Chaki, S; Nagamine, M; Nakazato, A; Ogawa, S; Okubo, T; Okuyama, S; Suzuki, Y; Tomisawa, K; Yoshikawa, R | 1 |
| Korkmaz, S; Wahlström, G | 1 |
| Kishi, E; Kuribara, H; Maruyama, Y | 1 |
| Aota, M; Harada, K; Inoue, T; Ishibashi, K; Matsuda, R; Matsuoka, N; Mihara, T; Yamaji, T | 1 |
| Ben-Attia, M; Ben-Cherif, W; Boughattas, NA; Dridi, D; Gharbi, R; Sebai, H | 1 |
| Can, OD; Ozkay, UD | 1 |
55 other study(ies) available for hexobarbital and diazepam
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
On the hypnogenic and anticonvulsant activities of demethyldiazepam and chlordemethyldiazepam: time-effect relations.
Topics: Animals; Anticonvulsants; Chlorprothixene; Diazepam; Female; Hexobarbital; Hypnotics and Sedatives; Mice; Nordazepam; Pentylenetetrazole; Time Factors | 1977 |
[Effect of psychotropic drugs on somatosensory evoked cortical potentials].
Topics: Animals; Anti-Anxiety Agents; Desipramine; Diazepam; Evoked Potentials; Female; Haloperidol; Hexobarbital; Medazepam; Piperidines; Rats; Somatosensory Cortex | 1979 |
[Experimental characteristics of the spectrum of pharmacologic activity of the tranquilizer lorazepam].
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Chlordiazepoxide; Conflict, Psychological; Diazepam; Drug Synergism; Hexobarbital; Humans; Hypnotics and Sedatives; Inhibition, Psychological; Mice; Muscle Relaxants, Central; Nicotine; Nitrazepam; Pentylenetetrazole; Rats; Reaction Time | 1975 |
The synthesis and pharmacology of a novel benzodiazepine derivative, 1-(beta-methylsulfonylethyl)-5-(o-fluorophenyl)-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (ID-622).
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Bemegride; Cats; Chlorprothixene; Diazepam; Drug Synergism; Electroencephalography; Electroshock; Female; Fluorobenzenes; Hexobarbital; Male; Mice; Motor Activity; Muscle Relaxants, Central; Rats; Reflex | 1975 |
Special experiments on central nervous effects of amitriptylinoxide considering pharmacokinetic aspects.
Topics: Administration, Oral; Amitriptyline; Animals; Anticonvulsants; Catalepsy; Central Nervous System; Diazepam; Electroshock; Hexobarbital; Humans; Injections, Intravenous; Kinetics; Male; Mice; Phenobarbital; Rats; Sleep; Tetrabenazine | 1978 |
[Experimental imipramine intoxication in the albino rat].
Topics: Animals; Diazepam; Electroencephalography; Hexobarbital; Imipramine; Male; Rats; Time Factors | 1978 |
Hypoxia-induced vasoconstriction in isolated perfused lungs exposed to injectable or inhalation anesthetics.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Animals; Diazepam; Dose-Response Relationship, Drug; Droperidol; Ether; Fentanyl; Halothane; Hexobarbital; Hypoxia; Ketamine; Methoxyflurane; Nitrous Oxide; Partial Pressure; Pentazocine; Pentobarbital; Rats; Thiopental; Vasomotor System; Ventilation-Perfusion Ratio | 1977 |
Effect of some central nervous system acting drugs on rat brain and liver monoamine oxidase activity.
Topics: Alcoholic Beverages; Animals; Brain; Central Nervous System; Chloralose; Diazepam; Ethanol; Hexobarbital; Imipramine; Liver; Male; Monoamine Oxidase; Rats | 1977 |
[Use of the Soviet preparation methindione for injections in convulsive conditions].
Topics: Adult; Anticonvulsants; Diazepam; Drug Therapy, Combination; Epilepsy; Female; Hexobarbital; Humans; Indans; Indenes; Injections, Intravenous; Male | 1976 |
[Hemodynamic effects of hexenal, seduxen and morphine in patients with low cardiac output].
Topics: Cardiac Output; Diazepam; Heart Valve Diseases; Hexobarbital; Humans; Mitral Valve; Morphine; Preanesthetic Medication | 1976 |
The effect of anesthesia on intraoperative and postoperative bleeding during abdominal prostatectomies: a comparison of neurolept anesthesia, halothane anesthesia and epidural anesthesia.
Topics: Adult; Aged; Anesthesia, Epidural; Anesthesia, Inhalation; Blood; Bupivacaine; Diazepam; Droperidol; Halothane; Hemorrhage; Hexobarbital; Humans; Lidocaine; Male; Middle Aged; Neuroleptanalgesia; Postoperative Complications; Pressure; Prostatectomy; Time Factors | 1975 |
Inhibition of drug metabolizing enzymes by diazepam in rat liver.
Topics: Aniline Compounds; Animals; Benzopyrenes; Cytochrome P-450 Enzyme System; Depression, Chemical; Diazepam; Hexobarbital; Male; Microsomes, Liver; Nitrobenzoates; Phenobarbital; Rats | 1975 |
[The pharmacology of Amaryllidaceae alkaloid tacettin].
Topics: Alkaloids; Animals; Atropine Derivatives; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Hexobarbital; Lethal Dose 50; Male; Mice | 1975 |
[The influence of propranolol on the circadian fluctuations in the duration of the hypnogenic effect of diazepam and hexenal].
Topics: Animals; Circadian Rhythm; Diazepam; Drug Interactions; Hexobarbital; Male; Mice; Propranolol; Reaction Time; Sleep; Time Factors | 1992 |
Pharmacological effects on two inbred substrains of AB mice.
Topics: Aggression; Animals; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Haloperidol; Hexobarbital; Mice; Mice, Inbred Strains; Neurotransmitter Agents; Pentylenetetrazole; Species Specificity | 1991 |
Interactions of brotizolam and diazepam with some psychotropic drugs on motor performance in mice.
Topics: Animals; Azepines; Desipramine; Diazepam; Drug Interactions; Ethanol; Female; Hexobarbital; Hypnotics and Sedatives; Mice; Psychomotor Performance; Psychotropic Drugs; Reflex; Time Factors | 1986 |
Central nervous actions and screening methods of antidepressants.
Topics: Acetylcholine; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Biogenic Amines; Blood Pressure; Brain Chemistry; Central Nervous System; Diazepam; Electroshock; Ethanol; Hexobarbital; Hypertension; Hypothermia, Induced; Imipramine; Iproniazid; Methamphetamine; Mice; Nialamide; Physostigmine; Piperidines; Reserpine; Tremorine | 1972 |
The synthesis and pharmacology of a novel benzodiazepine derivative, 1-methyl-5-(o-fluorophenyl)-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one(ID-540).
Topics: Aggression; Animals; Anti-Anxiety Agents; Behavior, Animal; Bemegride; Benzodiazepinones; Cats; Chlorprothixene; Diazepam; Drug Synergism; Electroencephalography; Electroshock; Female; Fluorobenzenes; Hexobarbital; Humans; Lethal Dose 50; Male; Mice; Motor Activity; Muscle Tonus; Olfactory Bulb; Pentylenetetrazole; Rats; Reflex; Seizures; Septum Pellucidum; Strychnine | 1974 |
Action of drugs on the electrical activity of the red nucleus.
Topics: Animals; Barbiturates; Cerebral Cortex; Chlordiazepoxide; Diazepam; Electrodes; Electrophysiology; Ethanol; Hexobarbital; Hippocampus; Male; Mephenesin; Meprobamate; Oxazepam; Pentobarbital; Phenobarbital; Rabbits; Red Nucleus; Thiopental; Urethane | 1969 |
Effects of the amygdalo-hippocampal evoked potential in the cat of four benzodiazepines and some other psychotropic drugs.
Topics: Amitriptyline; Amygdala; Animals; Benzazepines; Cats; Chlordiazepoxide; Chlorpromazine; Diazepam; Evoked Potentials; Female; Hexobarbital; Hippocampus; Male; Meprobamate | 1971 |
Role of drug metabolism in drug research and development: factors affecting metabolism of drugs and their pharmacological and toxicological activity.
Topics: Animals; Benzene Derivatives; Benzopyrenes; Cortisone; Cytochrome c Group; Cytochrome P-450 Enzyme System; Dealkylation; Diazepam; Female; Guinea Pigs; Hexobarbital; Hydroxylation; Male; Methylcholanthrene; Mice; Microsomes, Liver; Morphine; Oxidoreductases; Pentylenetetrazole; Pharmaceutical Preparations; Phenobarbital; Rats; Research; Sleep; Spironolactone | 1972 |
Comparative evaluation of the central nervous system activity of diazepam and its metabolites (demethyl-diazepam, methyl-oxazepam and oxazepam).
Topics: Animals; Central Nervous System; Dealkylation; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Female; Hexobarbital; Hydroxylation; Mice; Motor Activity; Muscle Relaxants, Central; Muscles; Oxazepam; Pentylenetetrazole; Sleep; Strychnine; Time Factors | 1974 |
Synthesis and CNS activity of 3-substituted 7-chloro-5-phenyl-1,3,4-benzotriazepin-2-ones.
Topics: Alkylation; Animals; Anticonvulsants; Behavior, Animal; Benzazepines; Central Nervous System; Chlordiazepoxide; Cricetinae; Cyclization; Depression, Chemical; Diazepam; Drug Synergism; Electroshock; Exploratory Behavior; Hexobarbital; Hypnotics and Sedatives; Lethal Dose 50; Mass Spectrometry; Methamphetamine; Mice; Motor Activity; Muscle Tonus; Pentylenetetrazole; Reflex; Sleep | 1974 |
Transitional electroencephalographic manifestations between ictal generalized spike-and-wave pattern and generalized repetitive fast discharge of the grand mal type.
Topics: Adolescent; Adult; Child; Diazepam; Electroencephalography; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Hexobarbital; Humans; Male; Sleep | 1968 |
Pharmacological studies on new potent central depressants, 8-chloro-6-phenyl-4H-s-triazolo [4,3a][1,4] benzodiazepine (D-40tA) and its 1-methyl analogue (D-65MT).
Topics: Administration, Oral; Aggression; Animals; Anticonvulsants; Antiemetics; Apomorphine; Avoidance Learning; Azepines; Behavior, Animal; Benzazepines; Cats; Central Nervous System; Chlordiazepoxide; Chlorprothixene; Diazepam; Discrimination Learning; Dogs; Drug Synergism; Female; Haplorhini; Hexobarbital; Humans; Injections, Intraperitoneal; Lethal Dose 50; Male; Mescaline; Methamphetamine; Mice; Morphine; Motor Activity; Muscle Relaxants, Central; Reserpine; Sleep; Tetrabenazine; Triazoles | 1971 |
[Characteristics of the development of tolerance to tranquilizers of the benzodiazepine series according to the muscle relaxant and sedative effects].
Topics: Animals; Chlordiazepoxide; Diazepam; Drug Tolerance; Hexobarbital; Male; Mice; Muscles; Nitrazepam; Oxazepam; Rats; Sleep; Tranquilizing Agents | 1972 |
[Pharmacological studies of a new minor tranquilizer, dipotassium chlorazepate (7-chloro-1,3-dihydro-2-oxo-5-phenyl-1H-1, 4-benzodiazepine 3-carboxylic acid monopotassium salt monopotassium hydroxide). 1. Central action].
Topics: Animals; Anticonvulsants; Apomorphine; Bemegride; Benzazepines; Central Nervous System; Cerebral Cortex; Diazepam; Dogs; Electroencephalography; Evoked Potentials; Hexobarbital; Hypothalamus; Limbic System; Male; Mice; Morphine; Nicotine; Pentylenetetrazole; Rats; Strychnine; Tranquilizing Agents; Tremorine | 1972 |
Chemistry and CNS-pharmacological properties of two hydrosoluble benzodiazepine derivatives.
Topics: Animals; Avoidance Learning; Behavior, Animal; Central Nervous System; Chemical Phenomena; Chemistry, Physical; Depression, Chemical; Diazepam; Dibenzazepines; Drug Synergism; Hexobarbital; Locomotion; Male; Methamphetamine; Motor Activity; Oxazepam; Pentylenetetrazole; Rats; Stimulation, Chemical; Time Factors | 1969 |
[Continuous sleep disorders].
Topics: Chlordiazepoxide; Delayed-Action Preparations; Diazepam; Hexobarbital; Humans; Hypnotics and Sedatives; Sleep Wake Disorders | 1970 |
Effects of various drugs on 3,4-dihydroxyphenylalanine (DL-DOPA)-induced excitation (agressive behavior) in mice.
Topics: Aggression; Animals; Antidepressive Agents; Autonomic Agents; Behavior, Animal; Bretylium Compounds; Chlordiazepoxide; Chlorpromazine; Diazepam; Dihydroxyphenylalanine; Drug Antagonism; Haloperidol; Hexobarbital; Humans; Imipramine; Iproniazid; Male; Mice; Morphine; Oxazepam; Reserpine; Tranquilizing Agents; Tranylcypromine; Trifluoperazine | 1970 |
[Comparison of the characteristics of the effect of tranquilizing agents under experimental and clinical conditions].
Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Diseases; Chlordiazepoxide; Depression, Chemical; Diazepam; Drug Synergism; Electroshock; Emotions; Hexobarbital; Humans; Hypnotics and Sedatives; Mental Disorders; Meprobamate; Mice; Morpholines; Movement; Muscle Relaxants, Central; Neurotic Disorders; Orientation; Oxazepam; Pentylenetetrazole; Rats; Schizophrenia; Strychnine; Tranquilizing Agents | 1971 |
The pharmacology and toxicology of midaflur.
Topics: Analgesics; Animals; Appetite; Avoidance Learning; Benzimidazoles; Body Temperature; Body Weight; Carbon Isotopes; Cardiovascular System; Cats; Central Nervous System; Chlordiazepoxide; Chlorpromazine; Decerebrate State; Diazepam; Dogs; Electroencephalography; Female; Glucuronates; Guinea Pigs; Hexobarbital; Imidazoles; Lethal Dose 50; Meprobamate; Mice; Muscle Relaxants, Central; Ovulation; Pentobarbital; Rabbits; Rats; Seizures; Tetrabenazine | 1971 |
The influence of cyclobarbital and diazepam on drug metabolism in vitro and their binding to cytochrome P-450.
Topics: Animals; Barbital; Barbiturates; Cytochrome P-450 Enzyme System; Diazepam; Ethylmorphine; Hexobarbital; In Vitro Techniques; Liver; Male; Morphine Derivatives; Oxazepam; Rats; Rats, Inbred Strains | 1984 |
Effects of cholecystokinin-like peptides on rearing activity and hexobarbital-induced sleep.
Topics: Animals; Behavior, Animal; Ceruletide; Cholecystokinin; Diazepam; Drug Interactions; Hexobarbital; Male; Mice; Naloxone; Sincalide; Sleep | 1980 |
Toxic interactions of benzyl alcohol with bacterial endotoxin.
Topics: Animals; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Endotoxins; Escherichia coli; Hexobarbital; Liver Diseases; Male; Mice; Naloxone; Rats; Rats, Inbred Strains; Sleep | 1984 |
[Effect of diazepam and barbiturates on the in vivo metabolism of halothane and enflurane in rats].
Topics: Animals; Barbiturates; Diazepam; Dose-Response Relationship, Drug; Enflurane; Half-Life; Halothane; Hexobarbital; Male; Methohexital; Pentobarbital; Rats; Rats, Inbred Strains; Thiopental | 1983 |
[Pharmacological characterization of novel pyridazines. Part 1: Physicochemical parameters, acute toxicity and action on the central nervous system (author's transl)].
Topics: Animals; Central Nervous System; Chemical Phenomena; Chemistry, Physical; Diazepam; Drug Interactions; Hexobarbital; Lethal Dose 50; Mice; Motor Activity; Pentylenetetrazole; Pyridazines | 1981 |
Synthesis and CNS activities of pyridopyrazinone and pyridodiazepinone derivatives.
Topics: Analgesics; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Central Nervous System Agents; Diazepam; DNA, Neoplasm; Exploratory Behavior; Hexobarbital; Male; Mice; Motor Activity; Muscle Relaxants, Central; Pain Measurement; Pyrazines | 1994 |
Maturation-related changes in tolerance development to hexobarbital after short term treatment with diazepam in the rat.
Topics: Aging; Animals; Diazepam; Drug Tolerance; Electroencephalography; Hexobarbital; Male; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1993 |
Tolerance to hexobarbital induced by short-term treatments with diazepam and tested with an EEG-threshold test in male rats.
Topics: Animals; Diazepam; Drug Tolerance; Electroencephalography; Hexobarbital; Injections, Intraperitoneal; Lipids; Male; Rats; Rats, Sprague-Dawley; Solutions; Suspensions | 1993 |
Anxiolytic and side-effect profile of LY354740: a potent, highly selective, orally active agonist for group II metabotropic glutamate receptors.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Avoidance Learning; Bridged Bicyclo Compounds; Convulsants; Cyclic AMP; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Hexobarbital; Humans; Male; Mice; Motor Activity; Rats; Receptors, Metabotropic Glutamate; Reflex, Startle; Sleep | 1998 |
Honokiol, a putative anxiolytic agent extracted from magnolia bark, has no diazepam-like side-effects in mice.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Bicuculline; Biphenyl Compounds; Diazepam; Hexobarbital; Learning; Lignans; Male; Memory; Mice; Mice, Inbred BALB C; Sleep; Substance-Related Disorders | 1999 |
Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106.
Topics: Acetamides; Anesthesia; Animals; Anti-Anxiety Agents; Benzodiazepinones; Brain; Buspirone; Cell Membrane; Diazepam; Exploratory Behavior; Flunitrazepam; GABA Modulators; GABA-A Receptor Agonists; Hexobarbital; Isoquinolines; Male; Mice; Mice, Inbred ICR; Mitochondria; Motor Activity; Phenyl Ethers | 1999 |
Physical dependence after benzodiazepine treatments in rats: Comparison of short and long treatments with diazepam and lorazepam.
Topics: Animals; Anti-Anxiety Agents; Arousal; Brain; Diazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroencephalography; Hexobarbital; Lorazepam; Male; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substance-Related Disorders; Tissue Distribution | 1999 |
Does dihydrohonokiol, a potent anxiolytic compound, result in the development of benzodiazepine-like side effects?
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Biphenyl Compounds; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; GABA Modulators; Hexobarbital; Hypnotics and Sedatives; Learning; Male; Memory; Mice; Motor Activity; Sleep | 2000 |
Anxiolytic activity of a novel potent serotonin 5-HT2C receptor antagonist FR260010: a comparison with diazepam and buspirone.
Topics: Animals; Anti-Anxiety Agents; Buspirone; Calcium; Calcium Signaling; Central Nervous System Depressants; CHO Cells; Cricetinae; Diazepam; Drug Interactions; Ethanol; Exploratory Behavior; Feeding Behavior; Hexobarbital; Hypnotics and Sedatives; Interpersonal Relations; Male; Mesylates; Motor Activity; Neurotransmitter Transport Proteins; Piperazines; Postural Balance; Quinazolines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Sleep | 2006 |
Neuropharmacological screening of two 1,5-benzodiazepine compounds in mice.
Topics: Animals; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Benzopyrans; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Epilepsy, Tonic-Clonic; Flunitrazepam; GABA Agonists; Hexobarbital; Hypnotics and Sedatives; Male; Mice; Molecular Structure; Random Allocation; Receptors, GABA-A; Sleep | 2010 |
Effects of Hypericum montbretti extract on the central nervous system and involvement of GABA (A)/Benzodiazepine receptors in its pharmacological activity.
Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System; Diazepam; Exploratory Behavior; Hexobarbital; Hypericum; Hypnotics and Sedatives; Male; Mice; Motor Activity; Pentylenetetrazole; Plant Extracts; Receptors, GABA-A; Seizures; Sleep | 2012 |