hexobarbital and codeine

hexobarbital has been researched along with codeine in 34 studies

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	29 (85.29)	18.7374
1990's	1 (2.94)	18.2507
2000's	3 (8.82)	29.6817
2010's	1 (2.94)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Gillette, JR; Mitchell, JR; Sasame, HA; Thorgeirsson, SS	1
Ishii, Y; Kasuya, Y; Miyasaka, K; Watanabe, M	1
Borchert, HH; Pfeifer, S; Szołomicka-Orfinger, I	1
Cooper, DY; Rosenthal, O; Schleyer, H; Thomas, JH; Vars, HM	1
Chen, XH; de Zeeuw, RA; Ensing, K; Franke, JP; Temmink, A	1
Kasé, Y; Kito, G; Miyano, S; Miyata, T; Tachibana, K; Yuizono, T	1
Darby, FJ; Newnes, W; Price Evans, DA	1
Bacci, MC; Bianchi, C; Bonardi, G; Coppi, G; Molino, C; Tomasi, L; Vidi, A	1
Burke, DH; Mann, DE	1
Knabe, J; Strauss, D	1
Hansch, C; Martin, YC	1
Hildebrandt, AG	1
Bär, H; Behrend, U; Fermum, R; Grisk, A; Möritz, KU	1
Friedman, L; Quaife, ML	1
Mannering, GJ; Stitzel, RE; Tephly, TR	1
Wilson, JT	1
Fouts, JR; Gram, TE	1
Fouts, JR; Wilson, JT	1
Ackermann, E	1
Fouts, JR; Gram, TE; Rogers, LA	2
DIXON, RL; FOUTS, JR; ROGERS, LA	1
ALCANTARA, GA; FOUTS, JR; ROGERS, LA	1
DIXON, RL; FOUTS, JR; HART, LG; ROGERS, LA	1
FOUTS, JR	1
MANNERING, GJ; RUBIN, A; TEPHYL, TR	1
FOUTS, JR; ROGERS, LA	1
CRAM, RL; FOUTS, JR; JUCHAU, MR	1
FOUTS, JR; JOHANNESSON, T; ROGERS, LA; WOODS, LA	1
FOUTS, JR; MULLEN, JO	1

Other Studies

34 other study(ies) available for hexobarbital and codeine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
The role of cytochrome b5 in cytochrome P-450 enzymes. Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00 Topics: Aminopyrine; Animals; Benzphetamine; Codeine; Cytochrome P-450 Enzyme System; Cytochromes; Electron Transport; Ethylmorphine-N-Demethylase; Hexobarbital; Hydroxylation; Kidney; Lauric Acids; Microsomes; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Pharmaceutical Preparations; Rats; Sheep	1975
Potentiation of antitussive effect of codeine by some 1-dimethoxyphenyl-3-alkylaminobutanols in guinea pigs. Arzneimittel-Forschung, 1977, Volume: 27, Issue:7 Topics: Amino Alcohols; Analgesics; Anesthesia; Animals; Antitussive Agents; Codeine; Dogs; Drug Synergism; Female; Guinea Pigs; Hemodynamics; Hexobarbital; In Vitro Techniques; Lethal Dose 50; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Pulmonary Stretch Receptors; Respiration; Trachea	1977
[Metabolic drug interactions of trapidil (Rocornal)]. Die Pharmazie, 1978, Volume: 33, Issue:10 Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Codeine; Cytochrome P-450 Enzyme System; Depression, Chemical; Drug Interactions; Female; Glucosephosphate Dehydrogenase; Hexobarbital; Kinetics; Liver; Pyrimidines; Rats; Trapidil	1978
Comparison of the induction course, biophysical chemical interactions and photochemical action spectra of phenobarbital and 3-methylcholanthrene induce hepatic microsomal P-450. Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00 Topics: Aniline Compounds; Animals; Biotransformation; Body Weight; Carbon Monoxide; Codeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Hexobarbital; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital; Photochemistry; Polycyclic Compounds; Proadifen; Rats; Spectrum Analysis; Time Factors	1975
Application of Empore C-8 extraction disks for screening urine in systematic toxicological analysis. Journal of forensic sciences, 1992, Volume: 37, Issue:2 Topics: Barbiturates; Codeine; Dexetimide; Filtration; Hexobarbital; Humans; Imipramine; Methamphetamine; Molecular Structure; Nitrazepam; Prazepam; Pyrilamine	1992
Pharmacology of N-(2-picolyl)-N-phenyl-N-(2-piperidinoethyl)amine (TAT-3), a new antitussive agent. Arzneimittel-Forschung, 1969, Volume: 19, Issue:12 Topics: Analgesics; Anesthetics, Local; Animals; Anticonvulsants; Antiemetics; Antitussive Agents; Anura; Blood Pressure; Cats; Central Nervous System; Codeine; Constipation; Depression, Chemical; Dogs; Drug Synergism; Electroencephalography; Ethylamines; Guinea Pigs; Heart; Heart Rate; Hexobarbital; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Intestines; Male; Mice; Muscle Contraction; Mydriatics; Rabbits; Rats; Respiration; Stimulation, Chemical; Tremorine	1969
Human liver microsomal drug metabolism. Biochemical pharmacology, 1970, Volume: 19, Issue:4 Topics: Aged; Aniline Compounds; Codeine; Cytochromes; Enzyme Induction; Female; Hexobarbital; Humans; Male; Microsomes, Liver; Middle Aged; NADP; Oxidation-Reduction; Oxidoreductases; Spectrophotometry; Sulfites	1970
Experimental models for the in vivo evaluation of enzyme induction properties of drugs. Arzneimittel-Forschung, 1973, Volume: 23, Issue:12 Topics: Acetanilides; Amides; Aminopyrine; Amphetamine; Aniline Compounds; Animals; Central Nervous System; Codeine; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Hexobarbital; Male; Meperidine; Mice; Oxotremorine; Pentobarbital; Phenacetin; Phenytoin; Rabbits; Rats; Strychnine; Tolbutamide; Tremorine; Zoxazolamine	1973
Thiazine dye antagonism of opioid lethality in mice. Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:3 Topics: Animals; Codeine; Dextropropoxyphene; Drug Synergism; Hexobarbital; Lethal Dose 50; Levorphanol; Male; Meperidine; Methadone; Methylene Blue; Mice; Morphinans; Morphine; Sleep; Thiazines; Time Factors; Tolonium Chloride	1974
[Synthesis of optically active N-methylbarbiturates. 12. Barbituric acid derivatives]. Archiv der Pharmazie, 1972, Volume: 305, Issue:1 Topics: Acetates; Barbiturates; Codeine; Cyanides; Hexobarbital; Methylation; Optical Rotation; Phenobarbital; Quinine	1972
Influence of hydrophobic character on the relative rate of oxidation of drugs by rat liver microsomes. Journal of medicinal chemistry, 1971, Volume: 14, Issue:9 Topics: Aniline Compounds; Animals; Barbiturates; Caffeine; Chemical Phenomena; Chemistry, Physical; Chlorine; Codeine; Ephedrine; Fatty Alcohols; Hexobarbital; Kinetics; Male; Mathematics; Microsomes, Liver; Mixed Function Oxygenases; Naphthalenes; Oxidoreductases; Phenobarbital; Physostigmine; Rats; Solubility; Structure-Activity Relationship	1971
The binding of metyrapone to cytochrome P-450 and its inhibitory action on liver microsomal mixed-function oxidase reactions. The Biochemical journal, 1971, Volume: 125, Issue:2 Topics: Acetanilides; Aminopyrine; Animals; Binding Sites; Codeine; Cytochromes; Hexobarbital; Metyrapone; Microsomes, Liver; Morphinans; Nitrophenols; Oxidation-Reduction; Rats; Spectrum Analysis	1971
[Influence of various choleretics on biotransformation and biliary elimination of low molecular substances]. Acta biologica et medica Germanica, 1971, Volume: 27, Issue:1 Topics: Aminopyrine; Animals; Bile; Biotransformation; Cholagogues and Choleretics; Codeine; Dehydrocholic Acid; Female; Hexobarbital; Liver; Male; Mice; Morphine; Phenols; Procaine; Rats; Salicylamides; Salicylates; Thiocyanates	1971
Failure of the vitamin E-deficient rat to show decreased liver codeine-O-demethylase activity. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 133, Issue:3 Topics: Animals; Biotransformation; Body Weight; Codeine; Enzyme Induction; Hexobarbital; Liver; Male; Morphine; Organ Size; Rats; Spectrophotometry; Testis; Time Factors; Transferases; Vitamin E Deficiency	1970
Inhibition of drug metabolism. VI. Inhibition of hexobarbital metabolism in the isolated perfused liver of the rat. Molecular pharmacology, 1968, Volume: 4, Issue:1 Topics: Animals; Chlorpromazine; Codeine; Hexobarbital; In Vitro Techniques; Liver; Male; Morphine; Narcotics; Proadifen; Rats	1968
The effect of a pituitary mammotropic tumor on hepatic microsomal drug metabolism in the rat. Biochemical pharmacology, 1968, Volume: 17, Issue:7 Topics: Adenocarcinoma; Adrenal Glands; Aminopyrine; Aniline Compounds; Animals; Benzoates; Benzopyrenes; Body Weight; Codeine; Female; Glucosephosphate Dehydrogenase; Hexobarbital; Lactation; Liver; Male; Mammary Glands, Animal; Microsomes; Neoplasms, Experimental; Organ Size; Oxidoreductases; Pharmaceutical Preparations; Pigments, Biological; Pituitary Neoplasms; Pregnancy; Prolactin; Rats; Sex Factors; Sulfonamides; Zoxazolamine	1968
Time course differences in the metabolism of drugs by hepatic microsomes from rats, rabbits and mice. The Journal of pharmacology and experimental therapeutics, 1966, Volume: 152, Issue:3 Topics: Aminopyrine; Animals; Benzoates; Benzopyrenes; Codeine; Hexobarbital; In Vitro Techniques; Liver; Mice; Microsomes; Phenobarbital; Rabbits; Rats; Species Specificity; Sulfonamides; Time; Zoxazolamine	1966
The effect of chronic phenobarbital administration on some hepatic drug-metabolizing enzyme activities in the rat. Biochemical pharmacology, 1966, Volume: 15, Issue:8 Topics: Animals; Benzopyrenes; Codeine; Hexobarbital; Liver; Male; Microsomes; Nitrobenzenes; Phenobarbital; Rats	1966
[Syndnones as inhibitors of biotransformation]. Acta biologica et medica Germanica, 1966, Volume: 17, Issue:4 Topics: Aminopyrine; Animals; Biotransformation; Codeine; Hexobarbital; In Vitro Techniques; Liver; Microsomes; Oxadiazoles; Rats	1966
Further studies on the metabolism of drugs by subfractions of hepatic microsomes. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:3 Topics: Aminopyrine; Aniline Compounds; Animals; Benzopyrenes; Codeine; Hexobarbital; In Vitro Techniques; Male; Microsomes; Mixed Function Oxygenases; Nitrobenzenes; Nitrogen; Oxidoreductases; Pigments, Biological; Rabbits; Rats; Sulfonamides; Transferases; Zoxazolamine	1967
Effect of pretreatment of rabbits with phenobarbital or 3-methylcholanthrene on the distribution of drug-metabolizing enzyme activity in subfractions of hepatic microsomes. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:2 Topics: Aminopyrine; Amphetamine; Animals; Benzopyrenes; Codeine; Hexobarbital; Liver; Male; Methylcholanthrene; Microscopy, Electron; Microsomes; Mixed Function Oxygenases; Phenobarbital; Pigments, Biological; Rabbits; Zoxazolamine	1967
The effects of SKF 525-A on hepatic glycogen and rate of hepatic drug metabolism. Biochemical pharmacology, 1963, Volume: 12 Topics: Codeine; Hexobarbital; Ligases; Liver; Liver Glycogen; Muscle Relaxants, Central	1963
P-AMINOSALICYLIC ACID INDUCED PROLONGATION OF HEXOBARBITAL SLEEPING TIME. The Journal of pharmacology and experimental therapeutics, 1963, Volume: 142 Topics: Aminopyrine; Aminosalicylic Acid; Aminosalicylic Acids; Codeine; Hexobarbital; Liver; Liver Glycogen; Metabolism; Pharmacology; Rats; Research; Sleep	1963
THE METABOLISM OF DRUGS BY LIVER MICROSOMES FROM ALLOXAN-DIABETIC RATS: LONG TERM DIABETES. The Journal of pharmacology and experimental therapeutics, 1963, Volume: 142 Topics: Alloxan; Aminopyrine; Aniline Compounds; Animals; Codeine; Diabetes Mellitus, Experimental; Hexobarbital; Insulin; Liver; Liver Glycogen; Metabolism; Microsomes, Liver; Pharmacology; Phenobarbital; Rats; Research	1963
FACTORS AFFECTING HEPATIC MICROSOMAL ENZYME SYSTEMS INVOLVED IN DRUG METABOLISM. Advances in enzyme regulation, 1963, Volume: 1 Topics: Alloxan; Aminopyrine; Carcinoma, Hepatocellular; Chlordan; Chlorpromazine; Codeine; Hexobarbital; Jaundice; Jaundice, Obstructive; Liver; Liver Glycogen; Liver Neoplasms; Liver Regeneration; Microsomes; Phenobarbital; Portal System; Research; Starvation	1963
INHIBITION OF HEXOBARBITAL METABOLISM BY ETHYLMORPHINE AND CODEINE IN THE INTACT RAT. Biochemical pharmacology, 1964, Volume: 13 Topics: Acetanilides; Antimetabolites; Antitussive Agents; Blood; Codeine; Ethylmorphine; Hexobarbital; Meprobamate; Morphine; Pharmacology; Proadifen; Rats; Research	1964
SOME OF THE INTERACTIONS OF SKF 525-A WITH HEPATIC MICROSOMES. The Journal of pharmacology and experimental therapeutics, 1964, Volume: 146 Topics: Aminopyrine; Codeine; Dialysis; Fatty Acids; Hexobarbital; Iproniazid; Liver; Liver Glycogen; Metabolism; Microsomes; Microsomes, Liver; Proadifen; Rats; Renal Dialysis; Research	1964
DIFFERENCES IN HEPATIC DRUG METABOLISM IN VARIOUS RABBIT STRAINS BEFORE AND AFTER PRETREATMENT WITH PHENOBARBITAL. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 118 Topics: Aminopyrine; Amphetamine; Amphetamines; Aniline Compounds; Animals; Benzoates; Benzopyrenes; Chlorpromazine; Codeine; Hexobarbital; Liver; Metabolism; Phenobarbital; Rabbits; Research; Species Specificity; Transferases; Zoxazolamine	1965
THE EFFECT OF CODEINE TOLERANCE ON HEPATIC MICROSOMAL DRUG METABOLISM IN THE RAT. Acta pharmacologica et toxicologica, 1965, Volume: 22 Topics: Aminopyrine; Aniline Compounds; Benzoates; Benzopyrenes; Chlorpromazine; Codeine; Drug Tolerance; Hexobarbital; Liver; Metabolism; Morphine; Rats; Research; Sulfonamides; Zoxazolamine	1965
PROLONGATION OF HEXOBARBITAL SLEEPING TIME AND INHIBITION OF HEPATIC DRUG METABOLISM BY ADRENERGIC BLOCKING AGENTS IN MICE. Biochemical pharmacology, 1965, Volume: 14 Topics: Adrenergic Antagonists; Aminopyrine; Aniline Compounds; Azepines; Body Temperature; Codeine; Hexobarbital; Hydralazine; Liver; Metabolism; Mice; Pharmacology; Phenols; Phenoxybenzamine; Phentolamine; Research; Sleep; Tolazoline; Yohimbine	1965