hexobarbital and cimetidine

hexobarbital has been researched along with cimetidine in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (58.33)	18.7374
1990's	1 (8.33)	18.2507
2000's	3 (25.00)	29.6817
2010's	1 (8.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Pelkonen, O; Puurunen, J	2
Gibaldi, M	1
Katz, LB; Scott, CK; Shriver, DA	1
Crouch, RK; el-Hage, A; Ferrans, VJ; Herman, EH; Yang, GC	1
Fontenelle, LJ; Garner, G; Soltani, B	1
Homann, J; Kamenisch, W; Kratz, F; Leimenstoll, G; Matthes, KJ; Paul, F	1
Drew, R; Grygiel, JJ; Rowell, J	1

Reviews

1 review(s) available for hexobarbital and cimetidine

Article	Year
Drug interactions: Part I. The Annals of pharmacotherapy, 1992, Volume: 26, Issue:5 Topics: Antidepressive Agents, Tricyclic; Caffeine; Cimetidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Fluconazole; Fluoxetine; Hexobarbital; Humans; Ketoconazole; Nimodipine; Oxidoreductases; Pharmaceutical Preparations; Rifampin; Stereoisomerism; Warfarin; Zidovudine	1992

Article

Year

Drug interactions: Part I.

The Annals of pharmacotherapy, 1992, Volume: 26, Issue:5

Topics: Antidepressive Agents, Tricyclic; Caffeine; Cimetidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Fluconazole; Fluoxetine; Hexobarbital; Humans; Ketoconazole; Nimodipine; Oxidoreductases; Pharmaceutical Preparations; Rifampin; Stereoisomerism; Warfarin; Zidovudine

1992

Other Studies

11 other study(ies) available for hexobarbital and cimetidine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Cimetidine inhibits microsomal drug metabolism in the rat. European journal of pharmacology, 1979, May-01, Volume: 55, Issue:3 Topics: Aminopyrine; Animals; Benzopyrenes; Cimetidine; Guanidines; Half-Life; Hexobarbital; Male; Microsomes, Liver; Pharmaceutical Preparations; Rats; Sleep; Time Factors	1979
Pharmacological profile of etintidine, a new histamine H2-receptor antagonist. Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 281, Issue:1 Topics: Animals; Cimetidine; Constriction; Dogs; Female; Gastric Juice; Guinea Pigs; Heart Atria; Hemagglutination Tests; Hexobarbital; Histamine; Histamine H2 Antagonists; Imidazoles; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Parietal Cells, Gastric; Pepsin A; Prolactin; Pylorus; Rabbits; Radioligand Assay; Rats; Rats, Inbred Strains; Sleep	1986
Mechanism of the protective activity of ICRF-187 against alloxan-induced diabetes in mice. Research communications in chemical pathology and pharmacology, 1986, Volume: 52, Issue:3 Topics: Alloxan; Animals; Blood Glucose; Chelating Agents; Cimetidine; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Hexobarbital; Hyperglycemia; Male; Mice; Mice, Inbred ICR; Piperazines; Proadifen; Razoxane; Sleep; Stereoisomerism; Superoxide Dismutase	1986
Selective effects of mercaptoundecahydrododecaborate (Na2B12H11SH) on the hepatic microsomal mono-oxygenase enzyme system and on hexobarbital induced sleep in mice. Proceedings of the Western Pharmacology Society, 1988, Volume: 31 Topics: Animals; Borohydrides; Cimetidine; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Hexobarbital; Male; Mice; Mice, Inbred CBA; Microsomes, Liver; Reference Values; Sleep; Sulfhydryl Compounds	1988
[Effect of cimetidine and ranitidine on drug metabolism of the liver]. Die Medizinische Welt, 1983, Mar-11, Volume: 34, Issue:10 Topics: Animals; Anti-Ulcer Agents; Cimetidine; Furans; Guanidines; Hexobarbital; Liver; Male; Metabolic Clearance Rate; Ranitidine; Rats; Rats, Inbred Lew; Sleep Stages	1983
Cimetidine: a specific inhibitor of hepatic aryl hydrocarbon hydroxylase (AHH) in the rat. Research communications in chemical pathology and pharmacology, 1981, Volume: 33, Issue:1 Topics: Aniline Hydroxylase; Animals; Aryl Hydrocarbon Hydroxylases; Cimetidine; Guanidines; Hexobarbital; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Sleep	1981
The effect of cimetidine on in vitro and in vivo microsomal drug metabolism in the rat. Biochemical pharmacology, 1980, Nov-15, Volume: 29, Issue:22 Topics: Aminopyrine; Animals; Cimetidine; Guanidines; Hexobarbital; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Pharmaceutical Preparations; Rats; Sleep; Time Factors	1980