hexobarbital and carbon monoxide

hexobarbital has been researched along with carbon monoxide in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199024 (96.00)18.7374
1990's0 (0.00)18.2507
2000's1 (4.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abraham, MH; Acree, WE; Ibrahim, A1
Dvorchik, BH; Hartman, RD; Marietta, MP; Vesell, ES; Weisz, J1
Krauss, P; Nehls, P; Remmer, H; Synder, R; Witmer, C1
Cooper, DY; Rosenthal, O; Schleyer, H; Thomas, JH; Vars, HM1
Miyazaki, Y; Motohashi, Y; Okeda, R; Takano, T1
Rösen, P; Stier, A2
Brownie, AC; Elmamlouk, TH; Gessner, T1
Illing, HP; Netter, KJ1
Cram, RL; Fouts, JR; Juchau, MR1
Estabrook, RW; Remmer, H; Schenkman, JB1
Gigon, PL; Gillette, JR; Gram, TE1
Gillette, JR; Sasame, HA1
Kaltiala, EH; Kärki, NT; Larmi, TK; Pelkonen, O1
Montgomery, MR; Rubin, RJ2
Dean, ME; Stock, BH1
Hodgson, E; Philpot, RM1
Cinti, DL; Kraschnitz, R; Moldeus, P; Orrenius, S; Schenkman, JB1
Reiner, O; Uehleke, H1
Casida, JE; Engel, JL; Matthews, HB; Skrinjarić-Spoljar, M1
Kappas, A; Poland, A1
George, WJ; Tephly, TR1
Cervantes, P; Gil, L; Oberti, C; Olate, J; Pedemonte, J1
VONPOST-LINGEN, ML1

Other Studies

25 other study(ies) available for hexobarbital and carbon monoxide

ArticleYear
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Characterization of cytochrome P-450-dependent aminopyrine N-demethylase in rat brain: comparison with hepatic aminopyrine N-demethylation.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:2

    Topics: Aminopyrine N-Demethylase; Androstenedione; Aniline Compounds; Animals; Benzopyrenes; Brain; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hexobarbital; In Vitro Techniques; Kinetics; Male; Meperidine; Microsomes; Microsomes, Liver; NAD; NADP; Proadifen; Proteins; Rats

1979
Optical and electron paramagnetic resonance studies of partially purified rabbit liver cytochrome P-450.
    Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00

    Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Dithionite; Electron Spin Resonance Spectroscopy; Hexobarbital; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rabbits; Spectrum Analysis

1975
Comparison of the induction course, biophysical chemical interactions and photochemical action spectra of phenobarbital and 3-methylcholanthrene induce hepatic microsomal P-450.
    Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00

    Topics: Aniline Compounds; Animals; Biotransformation; Body Weight; Carbon Monoxide; Codeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Hexobarbital; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital; Photochemistry; Polycyclic Compounds; Proadifen; Rats; Spectrum Analysis; Time Factors

1975
Direct effect of carbon monoxide on hexobarbital metabolism in the isolated perfused liver in the absence of hemoglobin.
    Journal of toxicology and environmental health, 1985, Volume: 15, Issue:6

    Topics: Animals; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Fluorometry; Hexobarbital; Hypoxia; Liver; Male; NAD; Oxygen Consumption; Rats; Rats, Inbred Strains; Spectrophotometry

1985
Kinetics of CO and O 2 complexes of rabbit liver microsomal cytochrome P 450 .
    Biochemical and biophysical research communications, 1973, Apr-02, Volume: 51, Issue:3

    Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hexobarbital; In Vitro Techniques; Kinetics; Microsomes, Liver; NADP; Oxygen Consumption; Phenobarbital; Photolysis; Protein Binding; Rabbits; Time Factors

1973
Proceedings: Kinetics of the binding of carbon monoxide and oxygen to microsomal cytochrome P450 and the influence of substrates.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Animals; Binding Sites; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Halothane; Hexobarbital; In Vitro Techniques; Kinetics; Ligands; Metyrapone; Microsomes, Liver; Oxygen Consumption; Phenobarbital; Photolysis; Rats; Spectrophotometry; Temperature; Tetrachloroethylene; Trichloroethylene

1974
Occurrence of cytochrome P-450 in hepatopancreas of Homarus americanus.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1974, Jul-15, Volume: 48, Issue:3

    Topics: Aniline Compounds; Animals; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Digestive System; Female; Hexobarbital; Microsomes; Morphinans; Nephropidae; Niacinamide; Protein Binding; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet; Thiocyanates

1974
Kinetic experiments on the synergistic effect of NADH on microsomal drug oxidation.
    Xenobiotica; the fate of foreign compounds in biological systems, 1974, Volume: 4, Issue:9

    Topics: Aniline Compounds; Animals; Anisoles; Carbon Monoxide; Chloromercuribenzoates; Drug Synergism; Hexobarbital; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NAD; Nitro Compounds; Oxidation-Reduction; Oxygen Consumption; Pharmaceutical Preparations; Pharmacology; Phenobarbital; Phenols; Proadifen; Pyridines; Rats; Spectrophotometry

1974
Stimulation by chlordane of hepatic drug metabolism in the squirrel monkey.
    The Journal of laboratory and clinical medicine, 1965, Volume: 66, Issue:6

    Topics: Aminopyrine; Animals; Benzoates; Benzopyrenes; Carbon Monoxide; Chlordan; Haplorhini; Hexobarbital; In Vitro Techniques; Liver; Microsomes; NADP; Oils; Organ Size; Zoxazolamine

1965
Spectral studies of drug interaction with hepatic microsomal cytochrome.
    Molecular pharmacology, 1967, Volume: 3, Issue:2

    Topics: Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Hexobarbital; In Vitro Techniques; Kinetics; Liver; Microsomes; NADP; Oxidoreductases; Rats; Spectrophotometry

1967
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.
    Molecular pharmacology, 1969, Volume: 5, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Sex Factors; Spectrophotometry; Time Factors; Valerates

1969
Studies on the relationship between the effects of various substances on absorption spectrum of cytochrome P-450 and the reduction of p-nitrobenzoate by mouse liver microsomes.
    Molecular pharmacology, 1969, Volume: 5, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzoates; Carbon Monoxide; Cytochromes; Ethylamines; Hexobarbital; Imidazoles; In Vitro Techniques; Kinetics; Liver; Male; Mice; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Proadifen; Pyridines; Spectrophotometry

1969
Cytochrome P-450-linked monooxygenase system and drug-induced spectral interactions in human liver microsomes.
    Chemico-biological interactions, 1974, Volume: 9, Issue:3

    Topics: Amines; Aniline Compounds; Animals; Antimetabolites; Benzene Derivatives; Butanols; Carbon Monoxide; Cholelithiasis; Cyanides; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Guinea Pigs; Hexobarbital; Humans; Liver; Microsomes, Liver; Oxygenases; Phenacetin; Proadifen; Rabbits; Rats; Smoking; Species Specificity; Spectrophotometry

1974
A study of the applicability of in vitro microsomal assays for detection of a possible carbon monoxide--P450 complex formed in vivo.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:4

    Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hexobarbital; In Vitro Techniques; Microsomes, Liver; Oxidoreductases; Oxygen; Rats

1972
Adaptation to the inhibitory effect of carbon monoxide inhalation on drug metabolism.
    Journal of applied physiology, 1973, Volume: 35, Issue:5

    Topics: Adaptation, Physiological; Animals; Atmosphere Exposure Chambers; Biotransformation; Carbon Monoxide; Environmental Exposure; Hexobarbital; Hypoxia; Liver; Male; Microsomes, Liver; Rats; Time Factors; Zoxazolamine

1973
Propylene glycol as a drug solvent in the study of hepatic microsomal enzyme metabolism in the rat.
    Toxicology and applied pharmacology, 1974, Volume: 28, Issue:1

    Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Benzoates; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dealkylation; Dose-Response Relationship, Drug; Hexobarbital; Hydroxylation; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Nitro Compounds; Pharmaceutical Preparations; Phenobarbital; Propylene Glycols; Rats; Sleep; Solvents; Time Factors

1974
The production and modification of cytochrome P-450 difference spectra by in vivo administration of methylenedioxyphenyl compounds.
    Chemico-biological interactions, 1972, Volume: 4, Issue:3

    Topics: Animals; Benzene Derivatives; Carbon Monoxide; Cytochromes; Depression, Chemical; Dicarboxylic Acids; Dioxoles; Enzyme Induction; Hexobarbital; Hydrogen-Ion Concentration; Male; Mice; Microsomes, Liver; Nitriles; Piperonyl Butoxide; Proteins; Pyridines; Spectrophotometry; Stimulation, Chemical; Structure-Activity Relationship; Sulfoxides; Time Factors

1972
The nature of the reverse type I (modified type II) spectral change in liver microsomes.
    Biochemistry, 1972, Nov-07, Volume: 11, Issue:23

    Topics: Alcohols; Aminopyrine; Aniline Compounds; Animals; Benzopyrenes; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Drug Synergism; Hexobarbital; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Phenacetin; Rabbits; Rats; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet

1972
[Binding of carbon tetrachloride to reduced microsomal cytochrome P-450 and to heme].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1971, Volume: 352, Issue:8

    Topics: Animals; Binding Sites; Carbon Monoxide; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cytochromes; Heme; Hexobarbital; Iron; Male; Microsomes, Liver; Oxidation-Reduction; Oxygen; Protein Binding; Rabbits; Spectrophotometry

1971
Response of hepatic microsomal mixed-function oxidases to various types of insecticide chemical synergists administered to mice.
    Biochemical pharmacology, 1971, Volume: 20, Issue:7

    Topics: Alkynes; Aniline Compounds; Animals; Anisoles; Benzopyrans; Carbamates; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Dimethyl Sulfoxide; Dioxoles; Drug Synergism; Enzyme Induction; Ethers; Hexobarbital; Hydrocarbons, Halogenated; Hydroxylation; In Vitro Techniques; Indoles; Insecticides; Male; Metyrapone; Mice; Microsomes, Liver; Mixed Function Oxygenases; Nitro Compounds; Nitrophenols; Organophosphorus Compounds; Organothiophosphorus Compounds; Oxidoreductases; Pesticide Synergists; Pesticides; Piperonyl Butoxide; Proadifen; Pyrazoles; Rotenone; Sleep; Spectrophotometry; Sulfites; Thiadiazoles; Time Factors

1971
The metabolism of aminopyrine in chick embryo hepatic cell culture: effects of competitive substrates and carbon monoxide.
    Molecular pharmacology, 1971, Volume: 7, Issue:6

    Topics: Aminopyrine; Animals; Antipyrine; Carbon Monoxide; Cells, Cultured; Chick Embryo; Dealkylation; Fatty Acids; Hexobarbital; Intestinal Mucosa; Kidney; Kinetics; Liver; Oxygen Consumption; Piperonyl Butoxide; Proadifen; Testosterone

1971
Studies on hepatic microsomal N- and O-dealkylation of morphine analogues.
    Molecular pharmacology, 1968, Volume: 4, Issue:5

    Topics: Animals; Carbon Monoxide; Cytochromes; Fasting; Hexobarbital; Hot Temperature; Kinetics; Light; Liver; Male; Microsomes; Morphine; Phenobarbital; Rats

1968
Alterations in mouse liver monooxygenases by benzothiadiazoles.
    Biochemical pharmacology, 1981, Jun-15, Volume: 30, Issue:12

    Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Enzyme Induction; Female; Hexobarbital; Liver; Mice; Mice, Inbred BALB C; Mixed Function Oxygenases; Oxidoreductases; Phenylalanine; Thiadiazoles; Time Factors

1981
THE SIGNIFICANCE OF EXPOSURE TO SMALL CONCENTRATIONS OF CARBON MONOXIDE: RESULTS OF AN EXPERIMENTAL STUDY ON HEALTHY PERSONS.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Air Pollution; Biomedical Research; Blood Gas Analysis; Carbon Monoxide; Flicker Fusion; Hexobarbital; Humans; Neurologic Examination; Pharmacology; Spirometry; Toxicology

1964