hexobarbital has been researched along with ascorbic acid in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (92.59) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bien, E; Kündiger, R; Müller, R; Skorka, G | 2 |
| Klinger, W; Reinicke, C | 2 |
| Dewhurst, F; Kitchen, DA | 1 |
| Kato, R; Oshima, T; Takanaka, A | 1 |
| Bousquet, WF; Fuller, GC; Miya, TS | 1 |
| Bader, M; Klinger, W; Thrum, H | 1 |
| Gmyrek, D; Grübner, I; Klinger, W | 1 |
| Klinger, W; Peter, EM; Schirrmeister, M | 1 |
| Degkwitz, E; Gundermann, K; Staudinger, H | 1 |
| Smith, PB; Wade, AE; Wu, B | 1 |
| Ankermann, H; Elger, J; Franke, H; Klinger, W; Reinicke, C; Traeger, A; Volkmann, H; Wahrenberg, I | 1 |
| Ankermann, H; Grübner, I; Klinger, W | 1 |
| Klinger, W | 3 |
| Klinger, W; Koch, M; Leibe, H | 1 |
| Klinger, W; Koch, M; Kramer, B | 1 |
| Klinger, W; Kramer, B | 1 |
| Bousquet, WF; Hoffman, DG; Miya, TS | 1 |
| Dargel, R; Karge, E; Klinger, W; Kretzschmar, M; Rein, H; Reinemann, C; Rost, M; Schulze, HP | 1 |
| BOUSQUET, WF; MIYA, TS; NEUMANN, NR | 1 |
| BOUSQUET, WF; MIYA, TS; RUPE, BD | 1 |
| CHIESARA, E; KATO, R; VASSANELLI, R | 1 |
1 review(s) available for hexobarbital and ascorbic acid
| Article | Year |
|---|---|
Current trends in hepatic response tests.
Topics: Aminopyrine; Animals; Ascorbic Acid; Circadian Rhythm; Cold Temperature; Cytochromes; DDT; Dietary Carbohydrates; Dietary Proteins; Dogs; Enzyme Induction; Guinea Pigs; Hepatomegaly; Hexobarbital; Humans; Hydrocarbons; Liver; Mice; Microsomes, Liver; NADP; Organ Size; Phenobarbital; Rabbits; Rats | 1969 |
26 other study(ies) available for hexobarbital and ascorbic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
[The excretion of hippuric acid and ascorbic acid in the urine of liver-damaged rats (author's transl].
Topics: Aminopyrine; Animals; Ascorbic Acid; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Enzymes; Female; Hexobarbital; Hippurates; Liver; Liver Function Tests; Male; Rats; Sleep; Thioacetamide; Time Factors | 1979 |
Influence of ibuprofen on drug-metabolizing enzymes in rat liver in vivo and in vitro.
Topics: Aminopyrine N-Demethylase; Animals; Ascorbic Acid; Drug Synergism; Hexobarbital; Ibuprofen; Kinetics; Liver; Male; Pharmaceutical Preparations; Phenobarbital; Propionates; Rats; Sleep; Time Factors | 1975 |
Effect of some 6-substituted benzo(a)pyrene derivatives upon liver enzymes and ascorbic acid excretion in mice.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Aniline Compounds; Animals; Ascorbic Acid; Benzopyrenes; Biotransformation; Diet; Enzyme Induction; Hexobarbital; In Vitro Techniques; Liver; Mice; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Oxidoreductases, N-Demethylating; Proteins; Spectrophotometry; Time Factors; Tyrosine Transaminase | 1973 |
Effect of vitamin C deficiency on the metabolism of drugs and NADPH-linked electron transport system in liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Diphenhydramine; Electron Transport; Guinea Pigs; Hexobarbital; Kidney; Liver; Male; Meperidine; Microsomes; NAD; NADP; Nitrobenzenes; Nitrophenols; Organ Size; p-Dimethylaminoazobenzene; Time Factors; Zoxazolamine | 1969 |
Effect of cold exposure on drug action and hepatic drug metabolism in the rat.
Topics: Adrenal Glands; Aminopyrine; Animals; Ascorbic Acid; Barbiturates; Carbon Isotopes; Cold Temperature; Cytochrome c Group; Cytochrome P-450 Enzyme System; Glycine; Hexobarbital; Kinetics; Liver; Male; Meprobamate; Microsomes, Liver; NADP; Oxidoreductases; Protein Biosynthesis; Rats | 1972 |
Actinomycin D: influence on induction of liver microsomal enzymes.
Topics: Aminopyrine N-Demethylase; Ascorbic Acid; Dactinomycin; Drug Interactions; Enzyme Induction; Hexobarbital; Microsomes, Liver; Sleep | 1974 |
[Studies of various substances and substance classes on induction properties. 3. Chlorinated insecticides].
Topics: Aminopyrine; Animals; Ascorbic Acid; Camphanes; Chlordan; DDT; Drug Synergism; Hexobarbital; Insecticides; Liver; Male; Methylation; Rats; Sleep | 1973 |
[Effect of beta-thiamino ketones on the amidopyrine-N-demethylation in vitro and in vivo as well as on hexobarbital sleeping time and L-ascorbic acid excretion in rats].
Topics: Amines; Aminopyrine; Animals; Ascorbic Acid; Hexobarbital; Leucyl Aminopeptidase; Liver; Male; Propiophenones; Rats; Sleep; Sulfides; Time Factors | 1973 |
[Mixed function oxygenation of (plus)- and (minus)-hexobarbital and spectral changes of cytochrome P-450 in the liver of guinea pigs fed without L-ascorbic acid (author's transl)].
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Cytochrome P-450 Enzyme System; Guinea Pigs; Hexobarbital; Kinetics; Liver; Mixed Function Oxygenases; Oxidoreductases; Spectrophotometry; Spectrophotometry, Ultraviolet; Stereoisomerism; Time Factors | 1973 |
Effects of ascorbic acid deficiency on kinetics of drug hydroxylation in male guinea pigs.
Topics: Aniline Compounds; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Cytochromes; Guinea Pigs; Hexobarbital; Hydroxylation; Kinetics; Liver; Male; Microsomes, Liver; Morphinans; Organ Size; Pharmaceutical Preparations; Phenobarbital; Proteins; Time Factors | 1972 |
Effects of non-steroid antirheumatic agents on microsomal drug-metabolizing enzymes of rat liver.
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Ascorbic Acid; Aspirin; Benzyl Compounds; Enzyme Induction; Flufenamic Acid; Hexobarbital; In Vitro Techniques; Indazoles; Indomethacin; Liver; Male; Mefenamic Acid; Methylamines; Methyltransferases; Microsomes, Liver; Organ Size; Oxidoreductases; Phenobarbital; Pyrazoles; Rats; Salicylamides; Salicylates; Sleep; Sodium Salicylate | 1971 |
[Studies on the mechanism of enzyme induction. XV. Induction pattern and submicroscopic changes in the liver following application of phenylbutazone in rats of different ages].
Topics: Age Factors; Aminopyrine; Animals; Animals, Newborn; Ascorbic Acid; Cholestasis; Endoplasmic Reticulum; Enzyme Induction; Female; Fetus; Hexobarbital; Liver; Lysosomes; Male; Methylcholanthrene; Microscopy, Electron; Mitochondria, Liver; Phenylbutazone; Pregnancy; Rats | 1970 |
[Various substances and substance classes with inductive properties. I. Aminoketones and aminoalcohols].
Topics: Amino Alcohols; Aminopyrine; Animals; Ascorbic Acid; Dealkylation; Hexobarbital; Ketones; Male; Propranolol; Rats; Sleep; Triazoles | 1971 |
[Studies on the mechanism of enzyme induction. XII. Effect of liver damage by CCl-4].
Topics: Animals; Ascorbic Acid; Barbiturates; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Dogs; Enzyme Induction; Hexobarbital; Sleep | 1968 |
[Investigations on the enzyme induction mechanism in rats and mice. 3. Effect of the pituitary anterior lobe-adrenal cortex system on the increase of elimination of ascorbic acid in rats and shortening of the sleeping period following hexobarbital adminis
Topics: Adrenal Glands; Animals; Ascorbic Acid; Enzymes; Female; Hexobarbital; Hypophysectomy; Male; Mice; Pituitary Gland; Rats; Sleep | 1965 |
[Investigations on the mechanism of enzyme induction in rats and mice. V. Influence of the gonads on 1-ascorbic acid normal excretion and its increase as well as on hexobarbital sleep duration and its reduction by barbital].
Topics: Animals; Ascorbic Acid; Barbiturates; Castration; Estradiol; Female; Gonadal Steroid Hormones; Gonads; Hexobarbital; Male; Mice; Rats; Sleep; Testosterone | 1965 |
[Investigations on the mechanism of enzyme induction in rats and mice. IV. Influence of age on 1-ascorbic acid excretion and its increase as well as on hexobarbital sleep duration and its reduction by barbital].
Topics: Aging; Animals; Ascorbic Acid; Barbiturates; Female; Hexobarbital; Male; Mice; Rats; Sleep | 1965 |
Lycorine inhibition of drug metabolism and ascorbic acid biosynthesis in the rat.
Topics: Alkaloids; Amines; Animals; Ascorbic Acid; Barbiturates; Hexobarbital; In Vitro Techniques; Liver; Meprobamate; Pentobarbital; Proadifen; Rats | 1966 |
[Studies on the mechanism of enzyme induction in rats and mice. VII. The effect of the thyroid gland on normal ascorbic acid excretion and its increase as well as on hexobarbital sleeping time and its reduction by barbital].
Topics: Animals; Ascorbic Acid; Barbiturates; Enzyme Induction; Female; Hexobarbital; Iodine Isotopes; Male; Methylthiouracil; Mice; Rats; Sleep; Thyroid Gland; Thyroxine | 1966 |
The excretion of ascorbic acid and hippuric acid in the urine of rats with liver injury.
Topics: Aminopyrine; Animals; Ascorbic Acid; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Female; Hexobarbital; Hippurates; Male; Rats; Sleep; Thioacetamide; Time Factors | 1980 |
Luminol-and lucigenin-amplified chemiluminescence with rat liver microsomes. Kinetics and influence of ascorbic acid, glutathione, dimethylsulfoxide, N-t-butyl-a-phenyl-nitrone, copper-ions and a copper complex, catalase, superoxide dismutase, hexobarbita
Topics: Acridines; Aniline Compounds; Animals; Ascorbic Acid; Catalase; Copper; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Glutathione; Hexobarbital; Iron; Kinetics; Luminescent Measurements; Luminol; Male; Microsomes, Liver; NADPH Dehydrogenase; Nitrogen Oxides; Proteins; Rats; Rats, Wistar; Superoxide Dismutase; Temperature; Time Factors | 1996 |
MECHANISM OF DEVELOPMENT OF TOLERANCE TO B-DIETHYLAMINOETHYL DIPHENYLPROPYLACETATE (SKF 525-A) IN THE RAT.
Topics: Adrenal Glands; Antimetabolites; Ascorbic Acid; Brain; Drug Tolerance; Ethionine; Hexobarbital; Liver; Metabolism; Pharmacology; Rats; Research; Sleep; Spleen; Urine | 1963 |
ENDOCRINE MODIFICATION OF DRUG RESPONSES IN THE RAT.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Ascorbic Acid; Barbiturates; Corticosterone; Hexobarbital; Histamine; Hypophysectomy; Injections, Intraperitoneal; Meprobamate; Pentobarbital; Pharmacology; Phenobarbital; Rats; Research; Stress, Physiological; Zoxazolamine | 1965 |
[STUDIES ON THE MECHANISM OF ENZYME INDUCTION IN RATS AND MICE. I. THE EFFECTS OF 6-MERCAPTOPURINE AND RIBOAZAURACIL ON THE INCREASE IN L-ASCORBIC ACID SECRETION AND THE REDUCTION OF HEXOBARBITAL SLEEPING TIME AFTER BARBITAL ADMINISTRATION].
Topics: Animals; Antimetabolites; Ascorbic Acid; Barbital; Body Fluids; Enzyme Induction; Fluids and Secretions; Hexobarbital; Mercaptopurine; Mice; Nucleosides; Pharmacology; Rats; Research; Sleep; Uracil; Urine | 1964 |
Stimulating effect of some inhibitors of the drug metabolisms (SKF 525 A, Lilly 18947, Lilly 32391 and MG 3062) on excretion of ascorbic acid and drug metabolisms.
Topics: Antineoplastic Agents; Ascorbic Acid; Biphenyl Compounds; Cytochrome P-450 Enzyme System; Ethylamines; Hexobarbital; Meprobamate; Muscle Relaxants, Central; Proadifen; Strophanthins | 1962 |