hexobarbital has been researched along with aminopyrine in 201 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 196 (97.51) | 18.7374 |
| 1990's | 3 (1.49) | 18.2507 |
| 2000's | 1 (0.50) | 29.6817 |
| 2010's | 1 (0.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asai, H; Izumi, K; Kato, K; Kitamikado, T; Ohno, S; Ohtani, O; Sugiura, S | 1 |
| Caron, G; Ermondi, G | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Klinger, W; Muller, D | 1 |
| Akashi, Y; Chiba, T; Horiuchi, M | 1 |
| Jansson, I; Schenkman, JB | 1 |
| Gillette, JR; Mitchell, JR; Sasame, HA; Thorgeirsson, SS | 1 |
| Ishiwata, H; Ohno, Y; Omori, Y; Takahashi, A; Tanimura, A | 1 |
| Pelkonen, O; Puurunen, J | 2 |
| Braun, R; Greeff, U; Netter, KJ | 1 |
| Bien, E; Kündiger, R; Müller, R; Skorka, G | 2 |
| Chanachai, W; Suriyachan, D; Thithapandha, A | 1 |
| Bartoli, GM; Burk, RF; Sies, H; Waydhas, C | 1 |
| Borchert, HH; Pfeifer, S; Szołomicka-Orfinger, I | 1 |
| Branch, RA; Rogers, L; Shand, DG; Villeneuve, JP; Wood, AJ | 1 |
| Ankermann, H; Klinger, W; Müller, D | 1 |
| Fukuyama, M; Miyake, Y; Nonaka, Y; Takayama, N | 1 |
| Canfield, RE; Kappas, A; Rifkind, AB | 1 |
| Becker, BA; Gut, I; Gutová, M | 1 |
| Chistiakov, VV; Lavretskaia, EF; Libinzon, RE; Mal'dov, DG; Ratnikov, LA | 1 |
| Catz, C; Ericksson, M; Yaffe, SJ | 1 |
| Lieber, CS; Pirola, RC | 1 |
| Becher, H; Klinger, W; Schnupp, P | 1 |
| Becker, BA; Gut, I | 1 |
| Gammans, RE; Sternson, LA | 1 |
| Ishikawa, M; Ozaki, M; Sasaki, K; Takayanagi, Y | 1 |
| Arvela, P; Lammintausta, R; Pelkonen, O; Puurunen, J | 1 |
| Bosio, A; Nebbia, C; Soffietti, MG; Ugazio, G | 1 |
| Leshchinskiĭ, AF | 1 |
| Ha, JR; Kim, HM; Park, SK; Yang, KH | 1 |
| Dennhardt, R; Gramm, HJ; Heinemeyer, G; Roots, I; Simgen, W | 1 |
| Breimer, DD; de Bree, H; Heij, P; van der Graaff, M; Vermeulen, NP | 1 |
| Antoni, F; Bánhegyi, G; Garzó, T; Mandl, J | 1 |
| Bien, E; Gebert, I; Skorka, G | 1 |
| Goto, S; Hirakawa, S; Inoue, K; Kanke, Y; Mizokami, K; Sunouchi, M; Suzuki, K; Takanaka, A | 1 |
| Baranova, NA; Danilov, VS; Ismailov, AD | 1 |
| Dewhurst, F; Kitchen, DA | 1 |
| Carlson, GP; DeFeo, JJ; Springfield, AC | 1 |
| Pelkonen, O | 1 |
| Whitehouse, MW | 1 |
| Bickel, MH; Gigon, PL | 1 |
| Gillette, JR; Kato, R | 1 |
| Cammer, W; Estabrook, RW; Schenkman, JB | 1 |
| Greengard, P; Quinn, GP; Reid, MB | 1 |
| Wilson, JT | 9 |
| Coon, MJ; Lu, AY; Strobel, HW | 2 |
| Abraham, R; Gangolli, SD; Gilbert, D; Goldberg, L; Martin, AD | 1 |
| Heni, N; Remmer, H | 1 |
| Commerford, SL; Hamilton, LD; Morahan, PS; Munson, AE; Regelson, W | 1 |
| Ahonen, J; Auranen, A; Hvitfelt, J | 1 |
| Ahonen, J; Auranen, A; Hvitfelt, KJ | 1 |
| Frohman, LA; Wilson, JT | 1 |
| Cram, RL; Fouts, JR; Juchau, MR | 2 |
| Fouts, JR; Gram, TE; Juchau, MR | 1 |
| Kato, R | 4 |
| Fouts, JR; Gram, TE | 2 |
| Gigon, PL; Gillette, JR; Gram, TE | 2 |
| Kato, R; Takanaka, A | 1 |
| Kato, R; Takanaka, A; Takayanagi, M | 1 |
| Gillette, JR; Sasame, HA | 1 |
| Kato, R; Oshima, T; Takanaka, A | 1 |
| Kato, R; Onoda, K; Takahashi, A; Takanaka, A | 1 |
| Fouts, JR; Peters, MA | 2 |
| Kato, R; Onoda, K; Takayanagi, M | 1 |
| Leibman, KC | 1 |
| Kupfer, D; Orrenius, S | 2 |
| Donahue, JD; Johnson, RK; Jondorf, WR; Miller, HH | 1 |
| Kato, R; Onoda, K; Sasajima, M | 1 |
| Boréus, LO; Orrenius, S; Rane, A; Sjöqvist, F; Yaffe, SJ | 1 |
| Fuller, GC; Lal, H; Olshan, A; Puri, SK | 1 |
| Banci, F; Tubaro, E | 1 |
| Kato, R; Onoda, K | 2 |
| Topham, JC | 1 |
| Grosse, W; Wade, AE | 1 |
| Bousquet, WF; Leber, P | 1 |
| Gillette, JR; Hamrick, M; Sasame, H; Stripp, B; Zampaglione, N | 1 |
| Orrenius, S | 1 |
| Gillette, JR; Hamrick, M; Stripp, B; Zampaglione, N | 1 |
| Bousquet, WF; Fuller, GC; Miya, TS | 1 |
| Cinti, DL; Moldeus, P; Schenkman, JB | 1 |
| Heikkinen, ER; Vainionpää, V; Vapaatalo, H | 1 |
| Kinoshita, G; Nakanishi, S; Shioara, E; Tsukada, M | 1 |
| Beck, FJ; Whitehouse, MW | 1 |
| Bresnick, E; Grogan, DE; Lane, M; Smith, FE; Stone, K | 1 |
| Dingell, JV; Heath, EC; Klausner, HA; Miller, KW | 1 |
| Gmyrek, D; Grübner, I; Klinger, W | 1 |
| Bradley, SG; Munson, AE; Rose, WC | 1 |
| Century, B | 1 |
| Kamataki, T; Kitada, M; Kitagawa, H | 2 |
| Klinger, W; Peter, EM; Schirrmeister, M | 1 |
| Bacci, MC; Bianchi, C; Bonardi, G; Coppi, G; Molino, C; Tomasi, L; Vidi, A | 1 |
| Kröner, H | 1 |
| Fischer, E; Szily, T; Varga, F | 1 |
| Feller, DR; Lewis, NJ; Witiak, DT | 1 |
| Bousquet, WF; Hadley, WM; Miya, TS | 1 |
| Oppermann, JA; Radzialowski, FM | 1 |
| Dean, ME; Stock, BH | 1 |
| Fouts, JR | 3 |
| Bousquet, WF; Radzialowski, FM | 2 |
| Endo, Y; Uchiyama, M | 1 |
| Neal, RA; Roth, JA | 1 |
| Neal, RA; Schulert, AR; Siami, G | 1 |
| Ewenike, HK; Farber, T; Sperling, F | 1 |
| Glaumann, H; Hietanen, E; von Bahr, C | 1 |
| Cinti, DL; Kraschnitz, R; Moldeus, P; Orrenius, S; Schenkman, JB | 1 |
| Brown, BR | 1 |
| Murai, S; Oizumi, Y; Ozawa, H; Seto, S | 1 |
| Remmer, H | 2 |
| Jori, A; Pescador, R; Pugliatti, C | 1 |
| Kato, R; Onoda, KI; Takanaka, A | 1 |
| Feuer, G; Lumb, G; Moddel, G; Sosa-Lucero, JC | 1 |
| Di Salle, E; Jori, A; Santini, V | 1 |
| Gerken, D; Yeary, RA | 1 |
| Hildebrandt, AG | 1 |
| Bär, H; Behrend, U; Fermum, R; Grisk, A; Möritz, KU | 1 |
| Kato, R; Onoda, K; Takanaka, A | 4 |
| Klinger, W; Reinicke, C | 1 |
| Kappas, A; Poland, A | 1 |
| Kato, R; Oshima, T; Takayanagi, M | 1 |
| Becker, BA; Eling, TE; Fouts, JR; Harbison, RD | 1 |
| Berman, ML; Bochantin, JF | 1 |
| Catz, CS; Juchau, MR; Yaffe, SJ | 1 |
| Kato, R; Takahashi, A; Takanaka, A | 2 |
| Jaffe, H; Neumeyer, JL | 1 |
| Classen, HG; Solymoss, B; Varga, S | 1 |
| Davis, DC; Gillette, JR; Gram, TE; Guarino, AM; Reagan, RL; Schroeder, DH | 1 |
| Kato, R; Takanaka, A; Takayanaghi, M | 1 |
| Ankermann, H; Elger, J; Franke, H; Klinger, W; Reinicke, C; Traeger, A; Volkmann, H; Wahrenberg, I | 1 |
| Jung, F; Kästner, D; Lange, P | 1 |
| Beuthin, PK; Bousquet, WF | 1 |
| Graham, PS; Hellyer, RO; Ryan, AJ | 1 |
| Ankermann, H; Grübner, I; Klinger, W | 1 |
| Fermum, R; Greiner-Leben, H; Hüller, H; Marx, E; Peters, R; Scheler, W | 1 |
| Kato, R; Takahashi, A | 1 |
| Dingell, JV; Heimberg, M | 1 |
| Calderoni, FJ; Mitoma, C; Neubauer, SE; Tagg, JS; Tanabe, M; Yasuda, D | 1 |
| Greene, FE; Wade, AE | 1 |
| Epstein, SS; Fujii, K; Guerin, H; Jaffe, H; Sengupta, M | 1 |
| Fouts, JR; Hansen, AR | 1 |
| Culp, HW; Gibson, WR; Marshall, FJ; McMahon, RE; Miller, WM; Mills, J | 1 |
| Bass, AD; Dingell, JV | 1 |
| Dreher, W; Freundt, KJ | 1 |
| Fouts, JR; Wilson, JT | 1 |
| Avnimelech, M; Jondorf, WR; Simon, DC | 1 |
| Dingell, JV; Hurwitz, L; Joiner, PD | 1 |
| Ackermann, E | 1 |
| Fouts, JR; Gram, TE; Rogers, LA | 2 |
| Badger, NL; Mitoma, C; Neubauer, SE; Sorich, TJ | 1 |
| Estabrook, RW; Frey, I; Remmer, H; Schenkman, JB | 1 |
| Jacob, V; Kästner, D; Rex, H; Schade, R; Sprang, C | 1 |
| Fujimori, K; Inoue, K; Kasuya, Y; Mizokami, K; Omori, Y; Sunouchi, M; Takanaka, A | 1 |
| Furusawa, S; Sasaki, K; Takayanagi, G | 1 |
| Bast, A; Noordhoek, J | 1 |
| Baranova, NA; Danilov, VS; Egorov, NS; Ismanlov, AD | 1 |
| Iyanagi, T; Kobayashi, S; Suzaki, T | 1 |
| Chodera, A; Mazurek, K | 1 |
| ADAMSON, RH; DIXON, RL; FOUTS, JR; HART, LG | 1 |
| FOUTS, JR; HART, LG; SHULTICE, RW | 1 |
| HOFFMEISTER, F | 1 |
| ENDROECZI, E; KORANYI, L; LISSAK, K | 1 |
| ALCANTARA, GA; FOUTS, JR; ROGERS, LA | 1 |
| DIXON, RL; FOUTS, JR; HART, LG; ROGERS, LA | 1 |
| FOUTS, JR; HART, LG | 1 |
| DIXON, RL; FOUTS, JR; ROGERS, LA | 1 |
| FOUTS, JR; ROGERS, LA | 1 |
| ALSLEBEN, B; LIEBENSCHUETZ, W; REMMER, H; SIEGERT, M | 1 |
| REMMER, H; SIEGERT, M | 1 |
| FOUTS, JR; JOHANNESSON, T; ROGERS, LA; WOODS, LA | 1 |
| FOUTS, JR; MULLEN, JO | 1 |
| ADAMSON, RH; FOUTS, JR; HART, LG; MORRIS, HP | 1 |
1 review(s) available for hexobarbital and aminopyrine
| Article | Year |
|---|---|
Current trends in hepatic response tests.
Topics: Aminopyrine; Animals; Ascorbic Acid; Circadian Rhythm; Cold Temperature; Cytochromes; DDT; Dietary Carbohydrates; Dietary Proteins; Dogs; Enzyme Induction; Guinea Pigs; Hepatomegaly; Hexobarbital; Humans; Hydrocarbons; Liver; Mice; Microsomes, Liver; NADP; Organ Size; Phenobarbital; Rabbits; Rats | 1969 |
200 other study(ies) available for hexobarbital and aminopyrine
| Article | Year |
|---|---|
Synthesis and antiinflammatory and hypnotic activity of 5-alkoxy-3-(N-substituted carbamoyl)-1-phenylpyrazoles.
Topics: Animals; Anti-Inflammatory Agents; Carbamates; Hypnotics and Sedatives; Lethal Dose 50; Mice; Pyrazoles | 1977 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developmental aspects of xenobiotic transformation.
Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Ethylmorphine; Female; Glucosephosphates; Hexobarbital; Hydrogen-Ion Concentration; Metyrapone; Microsomes, Liver; NAD; NADP; Niacinamide; Oxidoreductases, N-Demethylating; Oxidoreductases, O-Demethylating; Phenobarbital; Pregnancy; Rats; Semicarbazides | 1976 |
[Effect of thiol compounds on experimental liver damage (III). Effect of tiopronin (2-mercaptopropionylglycine) and glutathione on drug metabolizing activity (author's transl)].
Topics: Amino Acids, Sulfur; Aminopyrine; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Ethionine; Female; Glutathione; Hexobarbital; Liver Diseases; Microsomes, Liver; NADH Dehydrogenase; NADPH-Ferrihemoprotein Reductase; Pentobarbital; Rats; Sleep; Tiopronin | 1979 |
Interaction between microsomal electron transfer pathways.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Cytochrome Reductases; Cytochromes; Electron Transport; Ethylmorphine-N-Demethylase; Fatty Acids; Hexobarbital; Lipid Metabolism; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Peroxidases; Phenobarbital; Rats; Spectrum Analysis; Stearoyl-CoA Desaturase | 1975 |
The role of cytochrome b5 in cytochrome P-450 enzymes.
Topics: Aminopyrine; Animals; Benzphetamine; Codeine; Cytochrome P-450 Enzyme System; Cytochromes; Electron Transport; Ethylmorphine-N-Demethylase; Hexobarbital; Hydroxylation; Kidney; Lauric Acids; Microsomes; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Pharmaceutical Preparations; Rats; Sheep | 1975 |
Drug-nitrite interactions: species and sex differences in the formation of dimethylnitrosamine and its effects on the hepatic enzyme activities.
Topics: Aminopyrine; Animals; Dimethylnitrosamine; Female; Gastric Mucosa; Guinea Pigs; Hexobarbital; Liver; Male; Nitrites; Nitrosamines; Rats; Sex Factors; Sleep; Species Specificity; Time Factors | 1979 |
Cimetidine inhibits microsomal drug metabolism in the rat.
Topics: Aminopyrine; Animals; Benzopyrenes; Cimetidine; Guanidines; Half-Life; Hexobarbital; Male; Microsomes, Liver; Pharmaceutical Preparations; Rats; Sleep; Time Factors | 1979 |
Liver injury by the false morel poison gyromitrin.
Topics: Acetaldehyde; Aminopyrine; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Hexobarbital; Hydrazones; Liver; Microsomes, Liver; Mixed Function Oxygenases; Monomethylhydrazine; Mushroom Poisoning; Mycotoxins; Nitroanisole O-Demethylase; Rats; Sleep | 1979 |
[The excretion of hippuric acid and ascorbic acid in the urine of liver-damaged rats (author's transl].
Topics: Aminopyrine; Animals; Ascorbic Acid; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Enzymes; Female; Hexobarbital; Hippurates; Liver; Liver Function Tests; Male; Rats; Sleep; Thioacetamide; Time Factors | 1979 |
Testosterone as mediator of gamma--irradiation--induced damage in hepatic drug metabolism in the rat.
Topics: Aminopyrine; Animals; Female; Gamma Rays; Hexobarbital; Liver; Male; Mice; Radiation Injuries, Experimental; Rats; Testosterone | 1978 |
Glutathione efflux from perfused rat liver after phenobarbital treatment, during drug oxidations, and in selenium deficiency.
Topics: Aminopyrine; Animals; Dose-Response Relationship, Drug; Ethylmorphine; Glutathione; Hexobarbital; L-Lactate Dehydrogenase; Liver; Male; Oxidation-Reduction; Perfusion; Phenobarbital; Rats; Selenium | 1978 |
[Metabolic drug interactions of trapidil (Rocornal)].
Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Codeine; Cytochrome P-450 Enzyme System; Depression, Chemical; Drug Interactions; Female; Glucosephosphate Dehydrogenase; Hexobarbital; Kinetics; Liver; Pyrimidines; Rats; Trapidil | 1978 |
Impaired drug metabolism in experimental cirrhosis in the rat.
Topics: Aminopyrine; Animals; Half-Life; Hexobarbital; Kinetics; Liver; Liver Cirrhosis, Experimental; Male; Pharmaceutical Preparations; Propranolol; Rats | 1978 |
[The effect of symphathicotropic substances on liver microsomes in vivo and in vitro].
Topics: Aminopyrine; Animals; Dihydroergotamine; Ephedrine; Hexobarbital; In Vitro Techniques; Male; Microsomes, Liver; p-Dimethylaminoazobenzene; Propranolol; Rats; Sympatholytics; Sympathomimetics | 1975 |
Analysis of the reactivity of microsomal cytochrome P-450 toward drugs and exogenous ligands.
Topics: Aminopyrine; Aniline Compounds; Animals; Cyanides; Cytochrome P-450 Enzyme System; Hexobarbital; Kinetics; Male; Membranes; Microsomes, Liver; Models, Biological; Polyethylene Glycols; Protein Binding; Rats | 1977 |
Inhibition of chemical induction of porphyrin synthesis in chick embryo liver cells by partially purified human chorionic gonadotropin.
Topics: 5-Aminolevulinate Synthetase; Aminopyrine; Animals; Chick Embryo; Chorionic Gonadotropin; Enzyme Induction; Etiocholanolone; Hexobarbital; Humans; Liver; Meprobamate; Molecular Weight; Pentobarbital; Porphyrins; Secobarbital | 1976 |
Effect of pregnancy on hepatic microsomal drug metabolism in rabbits and rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Cytochrome P-450 Enzyme System; Female; Hexobarbital; Microsomes, Liver; Pharmaceutical Preparations; Pregnancy; Pregnancy, Animal; Rabbits; Rats; Species Specificity | 1976 |
[Interaction of psychotropic and anticonvulsive drugs].
Topics: Aminopyrine; Animals; Chlordiazepoxide; Chlorpromazine; Cytochrome P-450 Enzyme System; DNA; Hexobarbital; Imipramine; Liver; Male; Microsomes, Liver; Phenobarbital; Proteins; Rats; RNA | 1976 |
Effect of weanling malnutrition upon hepatic drug metabolism.
Topics: Aminopyrine; Aniline Compounds; Animals; Azo Compounds; Biotransformation; Cytochrome Reductases; Cytochromes; Hexobarbital; Liver; Male; Nitrophenols; Oxidation-Reduction; Protein Deficiency; Rats; Sulfates | 1975 |
Energy wastage in rats given drugs that induce microsomal enzymes.
Topics: Aminopyrine; Animals; Barbiturates; Body Weight; Energy Metabolism; Enzyme Induction; Ethanol; Female; Hexobarbital; Male; Microsomes, Liver; Oxygen Consumption; Phenobarbital; Rats | 1975 |
Daily rhythmic variation in hepatic amidopyrine-N-demethylation, hexobarbital sleeping time and acetanilide and phenazone toxicity in rats of different age.
Topics: Acetanilides; Age Factors; Aminopyrine; Animals; Antipyrine; Biotransformation; Circadian Rhythm; Hexobarbital; Liver; Male; Rats; Sleep | 1975 |
Heredity of hexobarbital sleeping time and efficiency of drug metabolism in Wistar and Sprague-Dawley rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzene; Biotransformation; Brain; Cytochrome P-450 Enzyme System; Female; Hexobarbital; In Vitro Techniques; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Molecular Biology; Organ Size; Proteins; Rats; Sex Factors; Sleep; Species Specificity | 1975 |
Effect of aromatic nitro compounds on oxidative metabolism by cytochrome P-450 dependent enzymes.
Topics: Aminopyrine; Aniline Compounds; Aniline Hydroxylase; Animals; Cytochrome P-450 Enzyme System; Energy Metabolism; Hexobarbital; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Nitro Compounds; Oxidation-Reduction; Rabbits; Zoxazolamine | 1976 |
Inhibition of hepatic drug biotransformation by carrageenan-induced inflammation in the rat: effect of sex hormone alterations.
Topics: Aminopyrine; Animals; Biotransformation; Carrageenan; Cytochrome P-450 Enzyme System; Estradiol; Ethylmorphine; Female; Gonadal Steroid Hormones; Hexobarbital; Inflammation; Male; Meperidine; Microsomes, Liver; Mixed Function Oxygenases; Orchiectomy; Ovariectomy; Rats; Rats, Wistar; Sex Characteristics; Testosterone | 1992 |
Comparative effects of medetomidine enantiomers on in vitro and in vivo microsomal drug metabolism.
Topics: Adrenergic alpha-Agonists; Aminopyrine; Animals; Cytochrome P-450 Enzyme System; Hexobarbital; Imidazoles; Male; Medetomidine; Microsomes, Liver; Rats; Rats, Inbred Strains; Stereoisomerism; Substrate Specificity | 1991 |
Age- and sex-related effects on hepatic drug metabolism in rats chronically exposed to dietary atrazine.
Topics: Age Factors; Aminopyrine; Aniline Compounds; Animals; Atrazine; Body Weight; Enzyme Induction; Female; Glutathione Transferase; Hexobarbital; Male; Maternal-Fetal Exchange; Microsomes, Liver; Pregnancy; Rats; Rats, Inbred Strains; Sleep | 1991 |
[Role of sex dimorphism in the pharmacological action of etimizol].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminopyrine; Animals; Biotransformation; Corticosterone; Creatine Kinase; Etimizol; Female; Hexobarbital; Imidazoles; Liver; Male; Mice; Myocardium; Rats; Sex Characteristics; Thyroid Hormones | 1989 |
Presence of hexobarbital in primary cultures of rat hepatocytes maintains cytochrome P-450 levels and drug metabolizing enzyme activities.
Topics: 1-Butanol; 7-Alkoxycoumarin O-Dealkylase; Aminopyrine; Aniline Compounds; Animals; Aryl Hydrocarbon Hydroxylases; Butanols; Cells, Cultured; Cyclohexanes; Cytochrome P-450 Enzyme System; Hexobarbital; Liver; Mixed Function Oxygenases; Oxygenases; Rats | 1988 |
Kinetics of hexobarbital and dipyrone in critical care patients receiving high-dose pentobarbital.
Topics: Adult; Aged; Aged, 80 and over; Aminopyrine; Critical Care; Dipyrone; Drug Interactions; Female; Glucaric Acid; Hexobarbital; Humans; Kinetics; Male; Middle Aged; Pentobarbital | 1987 |
Correlation between the metabolism of hexobarbital and aminopyrine in vivo in rats.
Topics: Administration, Oral; Aminopyrine; Animals; Aroclors; Carbon Tetrachloride; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Hexobarbital; Isoenzymes; Liver; Male; Metabolic Clearance Rate; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains | 1986 |
Interrelationship between aminopyrine oxidation and gluconeogenesis in hepatocytes prepared from fructose-pretreated mice.
Topics: Aminopyrine; Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Formaldehyde; Fructose; Gluconeogenesis; Hexobarbital; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Oxidation-Reduction; Phenobarbital | 1987 |
Biphasic effect of pyrazolone derivatives on drug-metabolizing enzyme in rat liver.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Biotransformation; Cytochrome P-450 Enzyme System; Dealkylation; Female; Hexobarbital; Liver; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Effects of oral contraceptive steroids (norethisterone/mestranol) on the activities of hepatic drug-metabolizing enzymes in iron-deficient anemic rats.
Topics: Aminopyrine; Anemia, Hypochromic; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Female; Hexobarbital; Mestranol; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Norethindrone; Rats; Rats, Inbred Strains | 1985 |
The inhibition of bacterial bioluminescence by xenobiotics.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochrome P-450 Enzyme System; Ethylmorphine; Hexobarbital; Luciferases; Luminescent Measurements; Morphine Derivatives; Vibrio | 1985 |
Effect of some 6-substituted benzo(a)pyrene derivatives upon liver enzymes and ascorbic acid excretion in mice.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Aniline Compounds; Animals; Ascorbic Acid; Benzopyrenes; Biotransformation; Diet; Enzyme Induction; Hexobarbital; In Vitro Techniques; Liver; Mice; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Oxidoreductases, N-Demethylating; Proteins; Spectrophotometry; Time Factors; Tyrosine Transaminase | 1973 |
Liver enlargement and modification of hepatic microsomal drug metabolism in rats by pyrethrum.
Topics: Aminopyrine; Animals; Anisoles; Body Weight; Chrysanthemum cinerariifolium; Colorimetry; Cytochrome Reductases; DNA; Dose-Response Relationship, Drug; Hepatomegaly; Hexobarbital; Inclusion Bodies; Liver; Male; Microsomes, Liver; NADP; Organ Size; Oxidation-Reduction; Pharmaceutical Preparations; Phytotherapy; Proteins; Rats; Spectrophotometry; Subcellular Fractions; Tryptophan Oxygenase; Water | 1973 |
Drug metabolism and drug-induced spectral interactions in human fetal liver microsomes.
Topics: Adult; Aminopyrine; Aminopyrine N-Demethylase; Aniline Compounds; Animals; Benzopyrenes; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Fetus; Hexobarbital; Humans; In Vitro Techniques; Ligands; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxygenases; Pharmaceutical Preparations; Rats; Spectrophotometry | 1973 |
Abnormal drug metabolism in rats after an inflammatory insult.
Topics: Adjuvants, Immunologic; Aminopyrine; Animals; Carrageenan; Corynebacterium; Cyclophosphamide; Hexobarbital; Inflammation; Liver; Male; Microsomes, Liver; Mycobacterium tuberculosis; Nocardia asteroides; Pharmaceutical Preparations; Rats; Rats, Inbred Strains; Sleep; Turpentine; Ultraviolet Rays | 1973 |
Drug metabolism by hepatic microsomes from phenobarbital-treated or starved male and female rats in the presence of inhibitors.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Female; Hexobarbital; Liver; Male; Methylation; Microsomes, Liver; Morphinans; Niacinamide; Organ Size; Phenobarbital; Proadifen; Rats; Starvation | 1971 |
Sex differences in the effects of abnormal physiological states on the metabolism of drugs by rat liver microsomes.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aminopyrine; Aniline Compounds; Animals; Castration; Diabetes Mellitus, Experimental; Epinephrine; Female; Formaldehyde; Hexobarbital; Hypoxia; In Vitro Techniques; Liver; Male; Microsomes; Mixed Function Oxygenases; Morphine; Rats; Sex; Thyroxine; Zoxazolamine | 1965 |
EPR measurements of substrate interaction with cytochrome P-450.
Topics: Adrenal Glands; Aminopyrine; Aniline Compounds; Animals; Cytochromes; Electron Spin Resonance Spectroscopy; Hexobarbital; In Vitro Techniques; Liver; Microsomes; Rats | 1966 |
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine | 1966 |
Decreased hepatic microsomal drug metabolism after the injection of a mixture containing somatotropin, corticotropin and prolactin.
Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Cattle; Depression, Chemical; Formaldehyde; Growth Hormone; Hexobarbital; Hot Temperature; Liver; Male; Morphinans; Prolactin; Rats; Sheep; Time Factors | 1968 |
Prevention of the normal postnatal increase in drug-metabolizing enzyme activity in rat liver by a pituitary tumor.
Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Benzoates; Biotransformation; Growth Hormone; Hexobarbital; Liver; Male; Microsomes; Neoplasm Transplantation; Neoplasms, Experimental; Pharmaceutical Preparations; Pituitary Neoplasms; Prolactin; Rats | 1968 |
Identification of somatotropin as the hormone in a mixture of somatotropin, adrenocorticotropic hormone and prolactin which decreased liver drug metabolism in the rat.
Topics: Adrenocorticotropic Hormone; Albumins; Aminopyrine; Animals; Formaldehyde; Growth Hormone; Hexobarbital; Liver; Male; Microsomes; Morphinans; Prolactin; Rats | 1969 |
Further observations on hepatic drug metabolism in rats treated with a mixture of somatotropin, corticotropin and prolactin.
Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Growth Hormone; Hexobarbital; Liver; Male; Microsomes, Liver; Morphinans; Neoplasm Transplantation; Phenobarbital; Pituitary Neoplasms; Prolactin; Rats | 1969 |
Pituitary mammotropic tumor in rats: evidence for a dosage effect on organ weight and liver drug metabolism.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminopyrine; Animals; Biotransformation; Growth Hormone; Hexobarbital; Liver; Male; Neoplasm Transplantation; Organ Size; Pituitary Neoplasms; Prolactin; Rats; Testis | 1969 |
Properties of a solubilized form of the cytochrome P-450-containing mixed-function oxidase of liver microsomes.
Topics: Alkanes; Aminopyrine; Animals; Benzphetamine; Cyclohexanes; Cytochromes; Electron Transport Complex IV; Fatty Acids; Hexobarbital; Lipid Metabolism; Microsomes, Liver; Morphinans; Phosphatidylcholines; Rabbits; Rats; Solubility; Triolein | 1970 |
The effect of substituted phenols on liver weights and liver enzymes in the rat: structure-activity relationships.
Topics: Alcohol Oxidoreductases; Aminopyrine; Animals; Antioxidants; Cresols; Enzyme Induction; Female; Glucose-6-Phosphatase; Hexobarbital; Liver; Male; Organ Size; Oxidoreductases; Phenols; Rats | 1969 |
[Effect of carbon tetrachloride on endoplasmic enzymes in rat liver].
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cholinesterases; Cytochromes; Endoplasmic Reticulum; Formaldehyde; Glucose-6-Phosphatase; Hexobarbital; Male; Membranes; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Protein Binding; Rabbits; Rats; Spectrophotometry | 1971 |
Antiviral activity and side effects of polyriboinosinic-cytidylic acid complexes as affected by molecular size.
Topics: Adjuvants, Immunologic; Aminopyrine; Animals; Antineoplastic Agents; Antiviral Agents; Centrifugation, Density Gradient; Chromium Isotopes; Encephalomyocarditis virus; Endotoxins; Erythrocytes; Hemagglutination Tests; Hexobarbital; Interferons; Liver; Mice; Mice, Inbred Strains; Oxidoreductases; Phagocytosis; Poly I-C; Polynucleotides; Sheep; Structure-Activity Relationship; Virus Diseases | 1972 |
Effect of biliary tract obstruction on liver microsomes in the rat.
Topics: Aminopyrine; Animals; Biliary Tract Diseases; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; DNA; Glucose-6-Phosphatase; Glycine; Hexobarbital; Ligation; Liver; Microsomes, Liver; Organ Size; Phospholipids; Proteins; Rats; RNA; Time Factors | 1973 |
The effect of a distant reparative process on rat liver function.
Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Cellulose; Collagen; Cytochrome P-450 Enzyme System; Glucose-6-Phosphatase; Granulation Tissue; Hexobarbital; Liver; Magnesium; Male; Methylation; Microsomes, Liver; Organ Size; Phosphates; Phospholipids; Phosphorus Radioisotopes; Proteins; Rats; RNA; Time Factors; Wounds and Injuries | 1973 |
Concomitant association between high plasma levels of growth hormone and low hepatic mixed-function oxidase activity in the young rat.
Topics: Age Factors; Aminopyrine; Aniline Compounds; Animals; Animals, Newborn; Body Weight; Cytochrome c Group; Cytochrome P-450 Enzyme System; Electron Transport; Female; Growth Hormone; Hexobarbital; Kinetics; Liver; Microsomes, Liver; Morphine; Oxidoreductases; Pharmaceutical Preparations; Pregnancy; Radioimmunoassay; Rats | 1974 |
Stimulation by chlordane of hepatic drug metabolism in the squirrel monkey.
Topics: Aminopyrine; Animals; Benzoates; Benzopyrenes; Carbon Monoxide; Chlordan; Haplorhini; Hexobarbital; In Vitro Techniques; Liver; Microsomes; NADP; Oils; Organ Size; Zoxazolamine | 1965 |
Stimulation of hepatic microsomal drug-metabolizing enyme systems in primtes byDDT.
Topics: Aminopyrine; Animals; Benzoates; Benzopyrenes; DDT; Haplorhini; Hexobarbital; In Vitro Techniques; Liver; NADP; Zoxazolamine | 1966 |
Possible role of P-450 in the oxidation of drugs in liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Carisoprodol; Chlorpromazine; Cytochromes; Glutethimide; Hexobarbital; In Vitro Techniques; Liver; Microsomes; Oxidoreductases; Pentobarbital; Phenobarbital; Piperazines; Rats | 1966 |
Effects of starvation and refeeding on the oxidation of drugs by liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Diet; Electron Transport Complex IV; Female; Hexobarbital; Liver; Microsomes; NADP; Organ Size; Pigments, Biological; Rats; Starvation; Sucrose | 1967 |
Further studies on the metabolism of drugs by subfractions of hepatic microsomes. 3. Effects of the NADPH-generating system.
Topics: Aminopyrine; Aniline Compounds; Animals; Buffers; Citrates; Enzyme Induction; Glucosephosphate Dehydrogenase; Hexobarbital; Hexosephosphates; Isocitrate Dehydrogenase; Liver; Male; Microsomes; Mixed Function Oxygenases; NADP; Niacinamide; Rabbits | 1967 |
Effect of drug substrates on the reduction of hepatic microsomal cytochrome P-450 by NADPH.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; Kinetics; Liver; Male; Microsomes; Morphine; NADP; Niacinamide; Oxidation-Reduction; Pigments, Biological; Proadifen; Rats; Sex Factors; Spectrophotometry; Transferases | 1968 |
Metabolism of drugs in old rats. I. Activities of NADPH-linked electron transport and drug-metabolizing enzyme systems in liver microsomes of old rats.
Topics: Aging; Aminobenzoates; Aminopyrine; Aniline Compounds; Animals; Azo Compounds; Benzoates; Body Weight; Cytochromes; Electron Transport; Female; Hexobarbital; Liver; Male; Microsomes; NADP; Organ Size; Oxidation-Reduction; Oxidoreductases; Proteins; Rats; Sex Factors; Strychnine | 1968 |
Studies on the mechanism of sex difference in drug-oxidizing activity of liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Electron Transport; Electron Transport Complex IV; Female; Hexobarbital; Liver; Male; Mice; Microsomes; NADP; Oxidation-Reduction; Oxidoreductases; Rabbits; Rats; Sex Factors | 1968 |
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Sex Factors; Spectrophotometry; Time Factors; Valerates | 1969 |
Studies on the relationship between the effects of various substances on absorption spectrum of cytochrome P-450 and the reduction of p-nitrobenzoate by mouse liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzoates; Carbon Monoxide; Cytochromes; Ethylamines; Hexobarbital; Imidazoles; In Vitro Techniques; Kinetics; Liver; Male; Mice; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Proadifen; Pyridines; Spectrophotometry | 1969 |
Effect of vitamin C deficiency on the metabolism of drugs and NADPH-linked electron transport system in liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Diphenhydramine; Electron Transport; Guinea Pigs; Hexobarbital; Kidney; Liver; Male; Meperidine; Microsomes; NAD; NADP; Nitrobenzenes; Nitrophenols; Organ Size; p-Dimethylaminoazobenzene; Time Factors; Zoxazolamine | 1969 |
Species differences in the alteration of drug-metabolizing activities of liver microsomes by thyroxine treatment.
Topics: Aminopyrine; Aniline Compounds; Animals; Body Weight; Electron Transport; Female; Heart; Hexobarbital; In Vitro Techniques; Liver; Male; Mice; Microsomes; NADP; Nitrobenzenes; Organ Size; Oxidoreductases; Rabbits; Rats; Species Specificity; Thyroxine | 1969 |
The inhibitory effect of aureomycin (chlortetracycline) pretreatment on some rat liver microsomal enzyme activities.
Topics: Albumins; Aminopyrine; Animals; Body Weight; Chlortetracycline; Cytochromes; Depression, Chemical; Hexobarbital; Injections, Intraperitoneal; Liver; Magnesium; Male; Microsomes; NADP; Organ Size; Phenobarbital; Proteins; Rats; Sleep | 1969 |
Hydroxylation of benzphetamine and other drugs by a solubilized form of cytochrome P-450 from liver microsomes: lipid requirement for drug demethylation.
Topics: Aminopyrine; Animals; Appetite Depressants; Benzphetamine; Cytochromes; Depression, Chemical; Ethers; Fatty Acids; Formaldehyde; Hexobarbital; Lipid Metabolism; Liver; Microsomes; Mixed Function Oxygenases; Morphinans; NADP; Oxidoreductases; Phenethylamines; Phenobarbital; Propylamines; Rabbits; Spectrophotometry | 1969 |
Species difference in the inhibition of drug metabolism by liver microsomes by different inhibitors.
Topics: Aminopyrine; Aniline Compounds; Animals; Cocaine; Depression, Chemical; Drug Antagonism; Ethylamines; Hexobarbital; Histamine H1 Antagonists; Kinetics; Male; Meperidine; Mice; Microsomes, Liver; Morphine; Nitrophenols; Oxidation-Reduction; Pentobarbital; Pharmaceutical Preparations; Phenacetin; Phenylhydrazines; Piperazines; Proadifen; Rabbits; Rats; Species Specificity; Zoxazolamine | 1969 |
Effects of metyrapone on liver microsomal drug oxidations.
Topics: Acetanilides; Aminopyrine; Animals; Depression, Chemical; Hexobarbital; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Morphine; NADP; Phenobarbital; Rats; Sleep; Stimulation, Chemical; Trichloroethylene; Tyramine | 1969 |
Characteristics of guinea pig liver and adrenal monooxygenase systems.
Topics: Adrenal Glands; Aminopyrine; Aniline Compounds; Animals; Binding Sites; Cytochromes; Fatty Acids; Guinea Pigs; Hexobarbital; Hydrocortisone; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Spectrum Analysis; Succinates; Vitamin K | 1970 |
Hepatic drug-metabolizing enzyme activity in rats pretreated with (-)-emetine or (plus or minus)-2,3-dehydroemetine.
Topics: Aminopyrine; Animals; Depression, Chemical; Drug Synergism; Emetine; Female; Glucosephosphate Dehydrogenase; Hexobarbital; Liver; Microsomes, Liver; NADP; Phenobarbital; Rats; Sulfonamides | 1970 |
Effects of morphine treatment and starvation on the substrate interaction with P-450 in the oxidation of drugs by liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Blood Proteins; Castration; Chemical Phenomena; Chemistry; Depression, Chemical; Electron Transport; Female; Hexobarbital; In Vitro Techniques; Kinetics; Male; Methyltestosterone; Microsomes, Liver; Morphine; NADP; Oxidation-Reduction; Oxidoreductases; Pigments, Biological; Rats; Spectrophotometry; Starvation; Stimulation, Chemical; Testosterone; Zoxazolamine | 1970 |
The presence of a monooxygenase system in human fetal liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Carbon Isotopes; Cytochromes; Electron Transport; Fatty Acids; Fetus; Hexobarbital; Humans; In Vitro Techniques; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygenases; Spectrophotometry; Testosterone | 1970 |
Induction of hepatic drug metabolism in rats by methylchloroform inhalation.
Topics: Adrenal Glands; Adrenalectomy; Aminopyrine; Animals; Chloroform; Cycloheximide; Cytochromes; Dactinomycin; Enzyme Induction; Hexobarbital; In Vitro Techniques; Liver; Male; Meprobamate; Microsomes, Liver; Morphine; NADP; Protein Binding; Rats; Reflex; Zoxazolamine | 1970 |
Pharmacology of a nicotinamido-methylaminopyrazolone (Ra 101).
Topics: Aminopyrine; Amphetamine; Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Carrageenan; Croton Oil; Depression, Chemical; Dextrans; Drug Synergism; Edema; Female; Fever; Glutethimide; Granuloma; Hexobarbital; Histamine H1 Antagonists; Hypnotics and Sedatives; Male; Mice; Motor Activity; Pentylenetetrazole; Phenylbutazone; Polysaccharides, Bacterial; Pyrazoles; Rabbits; Rats; Seizures | 1970 |
The influence of magnesium and some other divalent cations on hepatic microsomal drug metabolism in vitro.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Calcium; Chlorides; Cobalt; Copper; Cytochromes; Edetic Acid; Hexobarbital; In Vitro Techniques; Iron; Magnesium; Male; Manganese; Microsomes, Liver; NADP; Nitrophenols; Phenobarbital; Potassium; Rats; Strontium; Sulfates; Zinc; Zoxazolamine | 1970 |
Studies on the regulation of the activity of drug oxidation in rat liver microsomes by androgen and estrogen.
Topics: Aminopyrine; Androgens; Animals; Castration; Cytochromes; Dealkylation; Diethylstilbestrol; Estradiol; Estrogens; Female; Hexobarbital; Kinetics; Male; Metabolism; Methylation; Methyltestosterone; Microsomes, Liver; Mixed Function Oxygenases; Muscles; NADP; Organ Size; Oxidoreductases; Protein Binding; Proteins; Rats; Seminal Vesicles; Spectrophotometry; Stimulation, Chemical; Testosterone; Tetrazolium Salts | 1970 |
Relationship between difference spectra and metabolism. Barbiturates, drug interaction and species difference.
Topics: Acetanilides; Acetates; Amino Alcohols; Aminopyrine; Aniline Compounds; Animals; Barbiturates; Binding Sites; Chemical Phenomena; Chemistry; Chlorpromazine; Cytochromes; Drug Antagonism; Drug Synergism; Ethanolamines; Hexobarbital; Macaca; Male; Mice; Microsomes, Liver; Pentobarbital; Phenobarbital; Proadifen; Propranolol; Protein Binding; Rats; Sleep; Species Specificity; Spectrophotometry; Thiazoles; Tremorine | 1970 |
The effect of thiamine consumption on liver microsomal drug-metabolizing pathways.
Topics: Aminopyrine; Aniline Compounds; Animals; Body Weight; Cytochromes; Diet; Esterases; Female; Glucosephosphate Dehydrogenase; Hexobarbital; Kinetics; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Organ Size; Oxidoreductases; Paralysis; Pharmaceutical Preparations; Phosphogluconate Dehydrogenase; Rats; Sex Factors; Sleep; Thiamine; Thiamine Deficiency; Zoxazolamine | 1971 |
Drug metabolism by an acetone powder from rat hepatic microsomes.
Topics: Acetone; Aminopyrine; Animals; Benzoates; Female; Glucosephosphate Dehydrogenase; Hexobarbital; Male; Methylation; Microsomes, Liver; NADP; Nitrophenols; Oxidation-Reduction; Rats; Sex Factors; Transferases | 1971 |
Studies of the stoichiometric relationships between the oxidation of drugs and the oxidation of reduced pyridine nucleotides by liver microsomal enzymes.
Topics: Adenine Nucleotides; Aminopyrine; Cytochromes; Hexobarbital; Imipramine; Microsomes, Liver; Morphinans; NADP; Nucleotides; Oxidation-Reduction; Pharmaceutical Preparations; Pyridines | 1971 |
Molecular aspects of drug metabolism.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Drug Interactions; Electron Transport; Fats; Hexobarbital; Hydroxylation; Lipids; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Pharmaceutical Preparations; Rats; Solubility; Spectrophotometry; Steroids; Testosterone; Triamcinolone | 1971 |
An approach measurement of the stoichiometric relationship between hepatic microsomal drug metabolism and the oxidation of reduced nicotinamide adenine dinucleotide phosphate.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Benzyl Compounds; Chlorine; Dealkylation; Ethylamines; Hexobarbital; Imipramine; Male; Methylamines; Microsomes, Liver; Morphine; NADP; Oxidation-Reduction; Pharmaceutical Preparations; Rats | 1972 |
Effect of cold exposure on drug action and hepatic drug metabolism in the rat.
Topics: Adrenal Glands; Aminopyrine; Animals; Ascorbic Acid; Barbiturates; Carbon Isotopes; Cold Temperature; Cytochrome c Group; Cytochrome P-450 Enzyme System; Glycine; Hexobarbital; Kinetics; Liver; Male; Meprobamate; Microsomes, Liver; NADP; Oxidoreductases; Protein Biosynthesis; Rats | 1972 |
Kinetic parameters of drug-metabolizing enzymes in Ca 2+ -sedimented microsomes from rat liver.
Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Calcium; Cell Fractionation; Centrifugation, Density Gradient; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Dealkylation; Hexobarbital; Kinetics; Male; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Rats; Spectrophotometry; Sucrose; Ultracentrifugation | 1972 |
Drug metabolism in spontaneously hypertensive rats.
Topics: Aminopyrine; Animals; Benzopyrenes; Blood Pressure; Cytochrome P-450 Enzyme System; Dealkylation; Female; Hexobarbital; Hydroxylation; Hypertension; Male; Microsomes, Liver; Pharmaceutical Preparations; Rats; Sleep; Time Factors | 1974 |
Effect of type I compounds on P-hydroxylation of aniline in vitro.
Topics: Aminopyrine; Aniline Compounds; Animals; Chlorpromazine; Depression, Chemical; Hexobarbital; Hydroxylation; In Vitro Techniques; Male; Microsomes, Liver; Rats | 1972 |
Impaired drug metabolism in rats associated with acute inflammation: a possible assay for anti-injury agents.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Azathioprine; Biological Assay; Cyclophosphamide; Dexamethasone; Disease Models, Animal; Drug Evaluation, Preclinical; Freund's Adjuvant; Hexobarbital; Humans; Hydroxylation; Inflammation; Irritants; Male; Mercaptopurine; Microsomes, Liver; Rats; Rats, Inbred Lew; Sleep; Time Factors | 1974 |
Interaction of flavins and chloramphenicol with microsomal enzyme systems.
Topics: Acetanilides; Aminopyrine; Animals; Anisoles; Chloramphenicol; Dealkylation; Drug Interactions; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Formaldehyde; Hexobarbital; Hydroxylation; In Vitro Techniques; Kinetics; Male; Mercaptopurine; Mice; Microsomes, Liver; Nitro Compounds; Organ Size; Proteins; Sleep; Time Factors | 1972 |
The intracellular localization of 9 -tetrahydrocannabinol in liver and its effects on drug metabolism in vitro.
Topics: Aminopyrine; Animals; Benzoates; Cannabis; Carbon Isotopes; Cell Nucleus; Dealkylation; Dronabinol; Estradiol; Glucuronates; Hexobarbital; Hexosyltransferases; In Vitro Techniques; Kinetics; Liver; Microsomes, Liver; Mitochondria, Liver; Nitrophenols; Oxidation-Reduction; Pharmaceutical Preparations; Proadifen; Rats; Tritium | 1973 |
[Studies of various substances and substance classes on induction properties. 3. Chlorinated insecticides].
Topics: Aminopyrine; Animals; Ascorbic Acid; Camphanes; Chlordan; DDT; Drug Synergism; Hexobarbital; Insecticides; Liver; Male; Methylation; Rats; Sleep | 1973 |
Acute lethality for mice following administration of cyclophosphamide with barbiturates.
Topics: Aminopyrine; Animals; Cyclophosphamide; Drug Synergism; Hexobarbital; Lethal Dose 50; Liver; Mice; Mice, Inbred BALB C; Microsomes, Liver; Mortality; Pentobarbital; Phenobarbital | 1973 |
A role of the dietary lipid in the ability of phenobarbital to stimulate drug detoxification.
Topics: Aminopyrine; Animals; Biotransformation; Chlorpromazine; Dietary Fats; Fatty Acids; Female; Glucosephosphate Dehydrogenase; Hexobarbital; In Vitro Techniques; Lipids; Liver; Mice; Mice, Inbred ICR; Microsomes, Liver; Phenobarbital; Rats; Sleep; Time Factors; Zoxazolamine | 1973 |
Some observations on the microsomal electron transport system and activities of drug oxidizing enzymes in human liver.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Aniline Compounds; Animals; Electron Transport; Hexobarbital; Humans; Hydroxylation; In Vitro Techniques; Male; Microsomes, Liver; Oxidoreductases; Rats; Spectrophotometry | 1973 |
[Effect of beta-thiamino ketones on the amidopyrine-N-demethylation in vitro and in vivo as well as on hexobarbital sleeping time and L-ascorbic acid excretion in rats].
Topics: Amines; Aminopyrine; Animals; Ascorbic Acid; Hexobarbital; Leucyl Aminopeptidase; Liver; Male; Propiophenones; Rats; Sleep; Sulfides; Time Factors | 1973 |
Experimental models for the in vivo evaluation of enzyme induction properties of drugs.
Topics: Acetanilides; Amides; Aminopyrine; Amphetamine; Aniline Compounds; Animals; Central Nervous System; Codeine; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Hexobarbital; Male; Meperidine; Mice; Oxotremorine; Pentobarbital; Phenacetin; Phenytoin; Rabbits; Rats; Strychnine; Tolbutamide; Tremorine; Zoxazolamine | 1973 |
[The relationship between the inhibition of protein synthesis and the induction of microsomal enzymes by barbital (author's transl)].
Topics: Aminopyrine; Animals; Barbiturates; Body Temperature; Enzyme Induction; Female; Hexobarbital; In Vitro Techniques; Liver; Liver Glycogen; Male; Microsomes, Liver; Organ Size; Protein Biosynthesis; Proteins; Rats; Time Factors; Zoxazolamine | 1973 |
Inhibition of microsomal drug metabolism by 2-((2-(4-pyridyl)-methyl)-thio)-benzimidazole (H-718).
Topics: Aminopyrine; Aniline Compounds; Animals; Barbital; Barbiturates; Benzimidazoles; Biotransformation; Chlorpromazine; Dose-Response Relationship, Drug; Drug Interactions; Esterases; Hexobarbital; Insecticides; Lethal Dose 50; Male; Microsomes, Liver; Oxotremorine; Parathion; Procaine; Pyridines; Rats; Sulfobromophthalein; Tremorine | 1973 |
Influence of clofibrate (ethyl-4-chlorophenoxyisobutyrate) on hepatic drug metabolism in male rats.
Topics: Age Factors; Aminopyrine; Aniline Compounds; Animals; Clofibrate; Cytochrome P-450 Enzyme System; Glucosephosphate Dehydrogenase; Hexobarbital; Hydroxylation; Liver; Male; Microsomes, Liver; Morphine; Pentobarbital; Proteins; Rats; Sleep; Zoxazolamine | 1974 |
Cadmium inhibition of hepatic drug metabolism in the rat.
Topics: Acetates; Aminopyrine; Animals; Anisoles; Body Weight; Cadmium; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Female; Glucosephosphate Dehydrogenase; Hexobarbital; Liver; Male; Mice; Microsomes, Liver; Nitro Compounds; Pharmaceutical Preparations; Progesterone; Rats; Sleep; Time Factors; Zoxazolamine | 1974 |
Effect of phencyclidine on hepatic drug metabolism in the rat.
Topics: Aminopyrine; Animals; Anisoles; Dealkylation; Hexobarbital; Hydroxylation; Liver; Male; Nitro Compounds; Oxidation-Reduction; Paralysis; Pharmaceutical Preparations; Phencyclidine; Rats; Sleep; Stimulation, Chemical; Time Factors; Zoxazolamine | 1974 |
Propylene glycol as a drug solvent in the study of hepatic microsomal enzyme metabolism in the rat.
Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Benzoates; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dealkylation; Dose-Response Relationship, Drug; Hexobarbital; Hydroxylation; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Nitro Compounds; Pharmaceutical Preparations; Phenobarbital; Propylene Glycols; Rats; Sleep; Solvents; Time Factors | 1974 |
Some in vitro assay conditions that affect detection and quantitation of phenobarbital-induced increases in hepatic microsomal drug-metabolizing enzyme activity.
Topics: Air; Aminopyrine; Aniline Compounds; Animals; Buffers; Enzyme Induction; Glass; Hexobarbital; Histological Techniques; In Vitro Techniques; Male; Medical Laboratory Science; Microsomes, Liver; Oxygen; Phenobarbital; Phosphates; Proteins; Rats; Sleep; Time Factors | 1970 |
Daily rhythmic variation in hepatic drug metabolism in the rat and mouse.
Topics: Adrenalectomy; Aminopyrine; Animals; Circadian Rhythm; Corticosterone; Female; Hexobarbital; Injections, Intramuscular; Injections, Intraperitoneal; Liver; Male; Mice; p-Dimethylaminoazobenzene; Pharmaceutical Preparations; Rats | 1968 |
Inhibition of hepatic drug-metabolizing enzymes by pyridoxine-5-disulfide 2HCl-2H 2 O(pyrithioxine).
Topics: Alcohol Oxidoreductases; Amino Acids; Aminopyrine; Animals; Carbon Isotopes; Cytochromes; Drug Synergism; Enzyme Inhibitors; Female; Glucosephosphate Dehydrogenase; Hexobarbital; Kinetics; Male; Meperidine; Methanol; Mice; Microsomes, Liver; Nitro Compounds; Picolines; Procaine; Protein Biosynthesis; Rats; Sex Factors; Sleep; Sulfides; Sulfones; Sulfoxides; Time Factors | 1970 |
Some effects of insecticides on hepatic microsomal enzymes in various animal species.
Topics: Adrenal Cortex Hormones; Aminopyrine; Animals; Chlordan; Contraceptives, Oral; DDT; Depression, Chemical; Enzyme Induction; Female; Haplorhini; Hexobarbital; Humans; Hydrocarbons; Hypnotics and Sedatives; Insecticides; Male; Mice; Microsomes, Liver; Oxidoreductases; Rats; Steroids; Zoxazolamine | 1970 |
Spectral studies of the binding of O,O-diethyl p-nitrophenylphosphorothionate (parathion) to cytochrome P-450.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Binding Sites; Cytochromes; Hexobarbital; Male; Microsomes, Liver; Morphinans; Parathion; Phenobarbital; Protein Binding; Rabbits; Spectrophotometry | 1972 |
A possible role for the mixed function oxidase enzyme system in the requirement for selenium in the rat.
Topics: Aminopyrine; Animals; Body Weight; Castration; Deficiency Diseases; Estradiol; Female; Feminization; Hexobarbital; Male; Microsomes, Liver; Nutritional Requirements; Oxidoreductases; Phenobarbital; Rats; Selenium; Sex Factors; Testosterone | 1972 |
Changes in LD 50 of parathion and hepatachlor following turpentine pretreatment.
Topics: Administration, Oral; Aminopyrine; Aniline Compounds; Animals; Benzopyrenes; Biotransformation; Dealkylation; Ethers, Cyclic; Heptachlor; Hexobarbital; Hydrocarbons, Halogenated; Insecticides; Lethal Dose 50; Male; Methyltransferases; Microsomes, Liver; Mixed Function Oxygenases; Parathion; Phenols; Rats; Sleep; Stimulation, Chemical; Turpentine | 1972 |
Oxidation and glucuronidation of certain drugs in various subcellular fractions of rat liver: binding of desmethylimipramine and hexobarbital to cytochrome P-450 and oxidation and glucuronidation of desmethylimipramine, aminopyrine, p-nitrophenol and 1-na
Topics: Aminopyrine; Animals; Cell Membrane; Cytochromes; Desipramine; Glucuronates; Golgi Apparatus; Hexobarbital; Hydroxylation; Liver; Male; Microsomes; Naphthalenes; Naphthols; Nitrophenols; Oxidation-Reduction; Rats; Spectrophotometry; Subcellular Fractions; Time Factors; Tritium | 1972 |
The nature of the reverse type I (modified type II) spectral change in liver microsomes.
Topics: Alcohols; Aminopyrine; Aniline Compounds; Animals; Benzopyrenes; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Drug Synergism; Hexobarbital; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Phenacetin; Rabbits; Rats; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet | 1972 |
The diphasic action of halothane on the oxidative metabolism of drugs by the liver. An in-vitro study in the rat.
Topics: Acetanilides; Acetone; Aminopyrine; Amobarbital; Aniline Compounds; Animals; Biotransformation; Depression, Chemical; Enzyme Induction; Halothane; Hexobarbital; Hydroxylation; Male; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Pentobarbital; Rats; Zoxazolamine | 1971 |
[Pharmacological studies of troponoids. I. Hypothermic, analgesic and anti-inflammatory actions of troponoids].
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Antipyrine; Aspirin; Body Temperature; Capillary Permeability; Chlorpromazine; Cycloheptanes; Erythema; Hexobarbital; Ketones; Male; Mice; Motor Activity; Pentylenetetrazole; Rats; Salicylates; Sleep; Strychnine | 1971 |
[Changes of drug effects caused by their metabolism in the liver].
Topics: Aminopyrine; Animals; Cytochromes; Dogs; Drug Stability; Endoplasmic Reticulum; Female; Fetus; Hexobarbital; Humans; Liver; Male; Metabolism; Mice; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Pregnancy; Rabbits; Rats; Thiopental | 1971 |
Rat strain differences in the activity of hepatic microsomal enzymes.
Topics: Aminopyrine; Amphetamine; Animals; Anisoles; Biotransformation; Brain; Dealkylation; Ethers; Female; Hexobarbital; Imipramine; Male; Microsomes, Liver; Nitro Compounds; Phenols; Rats; Species Specificity; Zoxazolamine | 1971 |
Species differences in the effect of morphine administration or adrenalectomy on the substrate interactions with cytochrome P-450 and drug oxidations by liver microsomes.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Aminopyrine; Androgens; Aniline Compounds; Animals; Cytochromes; Dealkylation; Depression, Chemical; Female; Hexobarbital; Male; Methylation; Mice; Microsomes, Liver; Morphine; Oxidation-Reduction; Protein Binding; Proteins; Rabbits; Rats; Sex Factors; Species Specificity; Spectrophotometry | 1971 |
Substrate induced difference spectrum of microsomal P-450 in human liver.
Topics: Aminopyrine; Aniline Compounds; Hexobarbital; Humans; Microsomes, Liver; Pigments, Biological; Proadifen; Spectrophotometry | 1971 |
Failure of various drugs to induce drug-metabolizing enzymes in extrahepatic tissues of the rat.
Topics: Adrenal Glands; Aminopyrine; Aniline Compounds; Animals; Brain; Chlorpromazine; Coumarins; Enzyme Induction; Female; Hexobarbital; Hydrochlorothiazide; Intestines; Kidney; Liver; Male; Methylcholanthrene; Metyrapone; Mixed Function Oxygenases; Organ Size; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors | 1971 |
Daily rhythmic variation and liver drug metabolism in rats.
Topics: Aminopyrine; Animals; Anisoles; Circadian Rhythm; Corticosterone; Ethers; Female; Hexobarbital; Imipramine; Liver; Microsomes, Liver; Nitro Compounds; Phenols; Rats; Rats, Inbred Strains | 1971 |
Hepatic drug metabolism in vitro in the horse.
Topics: Aminopyrine; Animals; Benzoates; Dealkylation; Female; Hexobarbital; Hexosyltransferases; Horses; Hydrolysis; In Vitro Techniques; Liver; Male; Nitro Compounds; Nitrophenols; Oxidation-Reduction; Pharmaceutical Preparations; Procaine; Uracil Nucleotides; Zoxazolamine | 1971 |
The binding of metyrapone to cytochrome P-450 and its inhibitory action on liver microsomal mixed-function oxidase reactions.
Topics: Acetanilides; Aminopyrine; Animals; Binding Sites; Codeine; Cytochromes; Hexobarbital; Metyrapone; Microsomes, Liver; Morphinans; Nitrophenols; Oxidation-Reduction; Rats; Spectrum Analysis | 1971 |
[Influence of various choleretics on biotransformation and biliary elimination of low molecular substances].
Topics: Aminopyrine; Animals; Bile; Biotransformation; Cholagogues and Choleretics; Codeine; Dehydrocholic Acid; Female; Hexobarbital; Liver; Male; Mice; Morphine; Phenols; Procaine; Rats; Salicylamides; Salicylates; Thiocyanates | 1971 |
Effect of adrenalectomy or alloxan diabetes on the substrate interaction with cytochrome P-450 in the oxidation of drugs by liver microsomes.
Topics: Adrenal Glands; Adrenalectomy; Aminopyrine; Aniline Compounds; Animals; Cytochromes; Diabetes Mellitus, Experimental; Female; Hexobarbital; Kinetics; Male; Microsomes, Liver; Oxidoreductases; Proteins; Rats; Rats, Inbred Strains; Sex Factors; Spectrum Analysis; Zoxazolamine | 1971 |
Effects of non-steroid antirheumatic agents on microsomal drug-metabolizing enzymes of rat liver.
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Ascorbic Acid; Aspirin; Benzyl Compounds; Enzyme Induction; Flufenamic Acid; Hexobarbital; In Vitro Techniques; Indazoles; Indomethacin; Liver; Male; Mefenamic Acid; Methylamines; Methyltransferases; Microsomes, Liver; Organ Size; Oxidoreductases; Phenobarbital; Pyrazoles; Rats; Salicylamides; Salicylates; Sleep; Sodium Salicylate | 1971 |
Substrate interaction with P-450 in the hydroxylation of drugs under abnormal physiological states.
Topics: Adrenal Glands; Adrenalectomy; Aminopyrine; Androgens; Aniline Compounds; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Female; Hexobarbital; Hydroxylation; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Morphine; Rats; Sex Factors; Spectrophotometry; Starvation; Thyroid Gland; Thyroidectomy; Thyroxine; Zoxazolamine | 1971 |
The metabolism of aminopyrine in chick embryo hepatic cell culture: effects of competitive substrates and carbon monoxide.
Topics: Aminopyrine; Animals; Antipyrine; Carbon Monoxide; Cells, Cultured; Chick Embryo; Dealkylation; Fatty Acids; Hexobarbital; Intestinal Mucosa; Kidney; Kinetics; Liver; Oxygen Consumption; Piperonyl Butoxide; Proadifen; Testosterone | 1971 |
Effect of morphine administration on the activities of microsomal drug-metabolizing enzyme systems in liver of different species.
Topics: Aminopyrine; Aniline Compounds; Animals; Female; Guinea Pigs; Hexobarbital; Liver; Male; Mice; Microsomes; Mixed Function Oxygenases; Morphine; Rabbits; Rats | 1966 |
Effect of administration of 3-aminotriazole on the activity of microsomal drug-metabolizing enzyme systems of rat liver.
Topics: Aminopyrine; Aniline Compounds; Animals; Blood Proteins; Brain; Brain Chemistry; Cytochromes; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Nitrobenzenes; Pentobarbital; Phenobarbital; Pigments, Biological; Rats; Spectrophotometry; Triazoles; Zoxazolamine | 1967 |
Differences in the oxidative metabolism of drugs by liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Oxidation-Reduction; Oxidoreductases; Pentobarbital; Phenobarbital; Proadifen; Rats; Sex Factors; Starvation; Thyroxine; Zoxazolamine | 1969 |
Species difference in drug metabolism by liver microsomes in alloxan diabetic or fasted animals. I. The activity of drug-metabolizing enzymes and electron transport system.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Diabetes Mellitus, Experimental; Electron Transport; Fasting; Female; Hexobarbital; In Vitro Techniques; Male; Mice; Microsomes, Liver; Oxidoreductases; Rabbits; Rats; Species Specificity; Starvation | 1970 |
Strain differences in the metabolism and action of drugs in mice and rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Diphenhydramine; Female; Hexobarbital; In Vitro Techniques; Male; Mice; Microsomes, Liver; Nitrobenzenes; Rats; Sex Factors; Species Specificity; Strychnine | 1970 |
Studies on age difference in mice for the activity of drug-metabolizing enzymes of liver microsomes.
Topics: Aging; Aminopyrine; Anesthesia; Aniline Compounds; Animals; Body Weight; Cytochromes; Electron Transport; Hexobarbital; In Vitro Techniques; Mice; Microsomes, Liver; Nitrobenzenes; Oxidoreductases; Paralysis; Strychnine; Zoxazolamine | 1970 |
Diphenylhydantoin effect on neonatal and adult rat hepatic drug metabolism.
Topics: Age Factors; Aminopyrine; Aniline Compounds; Animals; Animals, Newborn; Benzoates; Benzopyrenes; Benzphetamine; Body Weight; Cytochromes; Hexobarbital; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Microsomes, Liver; Mixed Function Oxygenases; Nitrophenols; Organ Size; Phenytoin; Proteins; Rats | 1970 |
Nonspecific stimulation of drug metabolism in rats by methoxyflurane.
Topics: Aminopyrine; Animals; Drug Tolerance; Enzyme Induction; Hexobarbital; Male; Methoxyflurane; Microsomes, Liver; Oxidoreductases; Rats; Sleep; Stimulation, Chemical; Tolbutamide | 1970 |
Effects of iron, riboflavin and iodide deficiencies on hepatic drug-metabolizing enzyme systems.
Topics: Age Factors; Aminopyrine; Aniline Compounds; Animals; Benzoates; Benzopyrenes; Biotransformation; Cytochromes; Deficiency Diseases; Hexobarbital; Hypothyroidism; Iodides; Iron; Mice; Microsomes, Liver; Nitrophenols; Propylthiouracil; Riboflavin; Riboflavin Deficiency; Sleep; Time Factors | 1970 |
Decrease in the substrate interaction with cytochrome P-450 in drug hydroxylation by liver microsomes from rats bearing Walker 256 carcinosarcoma.
Topics: Aminopyrine; Aniline Compounds; Animals; Carcinoma 256, Walker; Cytochromes; Female; Hexobarbital; Male; Microsomes, Liver; Proteins; Rats; Sex Factors; Spectrum Analysis; Testosterone | 1970 |
Comparative effects of piperonyl butoxide and N-(4-pentynyl)phthalimide on mammalian microsomal enzyme functions.
Topics: Aminopyrine; Animals; Dioxoles; Drug Synergism; Hexobarbital; Imides; Insecticides; Male; Mice; Microsomes, Liver; Phthalic Acids; Zoxazolamine | 1970 |
Effect of various steroids on microsomal aliphatic hydroxylation and N-dealkylation.
Topics: Alkylation; Aminopyrine; Animals; Enzyme Induction; Ethylestrenol; Female; Hexobarbital; Microsomes, Liver; Pregnanes; Progesterone; Rats; Spironolactone | 1970 |
The effect of starvation on the kinetics of drug oxidation by hepatic microsomal enzymes from male and female rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Female; Hexobarbital; Kinetics; Liver; Male; Microscopy, Electron; Microsomes, Liver; Morphinans; Oxidation-Reduction; Proteins; Rats; Sex Factors; Sleep; Starvation | 1970 |
Substrate-induced spectral change of liver microsomes in phenobarbital and methylcholanthrene-treated male and female rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Chemical Phenomena; Chemistry; Female; Hexobarbital; Male; Meperidine; Methylcholanthrene; Microsomes, Liver; Organ Size; Oxidation-Reduction; Phenobarbital; Proteins; Rats; Spectrophotometry; Spectrum Analysis; Zoxazolamine | 1970 |
Effect of thyroid hormone on the substrate interaction with P-450 in the oxidation of drugs by liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Female; Hexobarbital; Kinetics; Male; Microsomes, Liver; Oxidation-Reduction; Proteins; Rats; Spectrophotometry; Thyroidectomy; Thyroxine | 1970 |
[Studies on the mechanism of enzyme induction. XV. Induction pattern and submicroscopic changes in the liver following application of phenylbutazone in rats of different ages].
Topics: Age Factors; Aminopyrine; Animals; Animals, Newborn; Ascorbic Acid; Cholestasis; Endoplasmic Reticulum; Enzyme Induction; Female; Fetus; Hexobarbital; Liver; Lysosomes; Male; Methylcholanthrene; Microscopy, Electron; Mitochondria, Liver; Phenylbutazone; Pregnancy; Rats | 1970 |
[Influence of diethyldithiocarbamate on the CCl4-liver toxicity and the inhibition of the microsomal metabolism].
Topics: Aminopyrine; Animals; Carbon Tetrachloride; Hexobarbital; Mice; Microsomes, Liver; Rats; Thiocarbamates | 1970 |
Interaction of drugs, steroids and fatty acids with liver-microsomal cytochrome P-450.
Topics: Aminopyrine; Animals; Chemical Phenomena; Chemistry; Cytochromes; Fatty Acids; Hexobarbital; Male; Microsomes, Liver; Morphinans; Oxidation-Reduction; Oxygenases; Protein Binding; Rats; Spectrophotometry; Steroids; Testosterone; Triamcinolone Acetonide | 1970 |
Long-term variation in basal and phenobarbital-stimulated oxidative drug metabolism in the rat.
Topics: Aminopyrine; Animals; Basal Metabolism; Hexobarbital; In Vitro Techniques; Liver; Male; Nitrophenols; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Rats; Sleep; Time Factors | 1970 |
The inhibition of drug metabolism enzymes by some naturally occurring compounds.
Topics: Aminopyrine; Aniline Compounds; Animals; Azo Compounds; Biological Transport, Active; Biphenyl Compounds; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Coloring Agents; Endoplasmic Reticulum; Erythrocytes; Glucose; Golgi Apparatus; Hexobarbital; In Vitro Techniques; Lipid Metabolism; Liver; Liver Glycogen; Male; Mice; Oxidation-Reduction; Protein Binding; Rats; Sleep; Solubility; Time Factors | 1970 |
Altered rat hepatic drug metabolism after implantation of a pituitary mammotropic tumor (MtT), Walker carcinosarcoma or adenocarcinoma and after removal of the MtT.
Topics: Adenocarcinoma; Adrenal Glands; Aminopyrine; Animals; Carcinoma 256, Walker; Hexobarbital; Kidney; Liver; Male; Microsomes, Liver; Neoplasm Transplantation; Neoplasms, Experimental; Organ Size; Pituitary Neoplasms; Rats; Testis | 1971 |
[Various substances and substance classes with inductive properties. I. Aminoketones and aminoalcohols].
Topics: Amino Alcohols; Aminopyrine; Animals; Ascorbic Acid; Dealkylation; Hexobarbital; Ketones; Male; Propranolol; Rats; Sleep; Triazoles | 1971 |
[On pharmacology of a series of phenylalkylamines].
Topics: Aminopyrine; Analgesics; Animals; Appetite Depressants; Blood Pressure; Cardiovascular System; Chemical Phenomena; Chemistry; Female; Guinea Pigs; Heart; Hexobarbital; In Vitro Techniques; Male; Methamphetamine; Mice; Morphine; Movement; Phenethylamines; Propylamines; Rabbits; Rats | 1967 |
An investigation of the decrease in the metabolism of hexobarbital, aminopyrine and p-nitrobenzoic acid by liver from rats bearing a pituitary mammotropic tumor.
Topics: Adrenal Glands; Adrenalectomy; Aminopyrine; Animals; Benzoates; Castration; Hexobarbital; Liver; Male; Mammary Glands, Animal; Microsomes; Neoplasm Transplantation; Pituitary Neoplasms; Rats; Testis; Transplantation, Homologous | 1968 |
Thyroid hormone and activities of drug-metabolizing enzymes and electron transport systems of rat liver microsomes.
Topics: Alcohol Oxidoreductases; Aminopyrine; Aniline Compounds; Animals; Benzoates; Cytochromes; Depression, Chemical; Electron Transport; Female; Hexobarbital; Liver; Male; Microsomes; Nitrobenzenes; Oxidation-Reduction; Oxidoreductases; Pigments, Biological; Rats; Stimulation, Chemical; Tetrazolium Salts; Thyroid Gland; Thyroidectomy; Thyroxine; Triiodothyronine | 1968 |
The effects of aliphatic halogenated hydrocarbons on hepatic drug metabolism.
Topics: Aminopyrine; Animals; Antioxidants; Benzoates; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chloroform; Hexobarbital; Hydrocarbons, Halogenated; Liver; Male; Microsomes; Organ Size; Perfusion; Rats; Sleep; Solubility; Time Factors | 1968 |
Effects of various chemical agents on drug metabolism and cholesterol biosynthesis.
Topics: Acetanilides; Acetates; Aminopyrine; Animals; Anticholesteremic Agents; Benzopyrenes; Carbon Isotopes; Chloramphenicol; Cholesterol; Depression, Chemical; Drug Synergism; Ethers; Ethylamines; Hexobarbital; Insecticides; Iproniazid; Liver; Male; Mevalonic Acid; Microsomes; Nitrophenols; Phenobarbital; Proadifen; Rabbits; Rats; Sleep; Time Factors | 1968 |
Hepatic drug metabolism after phenobarbital or 3-methylcholanthrene pretreatment of rats bearing a pituitary tumor.
Topics: Aminopyrine; Animals; Benzopyrenes; Hexobarbital; Liver; Male; Methylcholanthrene; Phenobarbital; Pituitary Neoplasms; Rats; Zoxazolamine | 1968 |
The effect of a pituitary mammotropic tumor on hepatic microsomal drug metabolism in the rat.
Topics: Adenocarcinoma; Adrenal Glands; Aminopyrine; Aniline Compounds; Animals; Benzoates; Benzopyrenes; Body Weight; Codeine; Female; Glucosephosphate Dehydrogenase; Hexobarbital; Lactation; Liver; Male; Mammary Glands, Animal; Microsomes; Neoplasms, Experimental; Organ Size; Oxidoreductases; Pharmaceutical Preparations; Pigments, Biological; Pituitary Neoplasms; Pregnancy; Prolactin; Rats; Sex Factors; Sulfonamides; Zoxazolamine | 1968 |
The relationship of hepatic drug metabolizing activity to serum esterase activities in the albino rabbits.
Topics: Aminopyrine; Aniline Compounds; Animals; Atropine; Benzoates; Esterases; Female; Hexobarbital; Indenes; Liver; Liver Function Tests; Male; Naphthalenes; Procaine; Rabbits; Zoxazolamine | 1968 |
In vivo inhibition of mouse liver microsomal hydroxylating systems by methylenedioxyphenyl insecticidal synergists and related compounds.
Topics: Aminopyrine; Animals; Dioxoles; Drug Synergism; Eugenol; Hexobarbital; Insecticides; Liver; Mice; Microsomes; Mixed Function Oxygenases | 1968 |
Influence of 3,4-benzpyrene or gamma-chlordane on the rate of metabolism and acute toxicity of aminopyrine, hexobarbital, and zoxazolamine in the mouse.
Topics: Aminopyrine; Animals; Benzopyrenes; Chlordan; Drug Synergism; Enzyme Induction; Hexobarbital; Kinetics; Mice; Time Factors; Zoxazolamine | 1968 |
Demethylation studies. VI. The inhibition of hepatic microsomal oxygenation by 2,4-dichloro(6-phenylphenoxy)ethylamine and related compounds.
Topics: Aminopyrine; Amitriptyline; Animals; Butylamines; Carbamates; Carbon Isotopes; Dextropropoxyphene; Dogs; Ethylamines; Hexobarbital; Imipramine; In Vitro Techniques; Liver; Male; Mice; Microsomes; Morphinans; Naphthalenes; Nitriles; Phenethylamines; Phenobarbital; Propylamines; Rats | 1969 |
Inhibition of the hepatic metabolism of amphetamine by desipramine.
Topics: Aminopyrine; Amphetamine; Animals; Desipramine; Hexobarbital; In Vitro Techniques; Liver; Male; Perfusion; Rats; Tritium | 1969 |
Inhibition of drug metabolism by small concentrations of carbon disulfide.
Topics: Aminopyrine; Animals; Antipyrine; Carbon Disulfide; Depression, Chemical; Female; Hexobarbital; Liver; Procaine; Pyrazoles; Rats; Sleep | 1969 |
Time course differences in the metabolism of drugs by hepatic microsomes from rats, rabbits and mice.
Topics: Aminopyrine; Animals; Benzoates; Benzopyrenes; Codeine; Hexobarbital; In Vitro Techniques; Liver; Mice; Microsomes; Phenobarbital; Rabbits; Rats; Species Specificity; Sulfonamides; Time; Zoxazolamine | 1966 |
The effect of actinomycin D on post-phenobarbital activity of hepatic microsomal drug-metabolizing enzymes in the rat.
Topics: Aminopyrine; Animals; Dactinomycin; Hexobarbital; In Vitro Techniques; Liver; Microsomes; Phenobarbital; Rats | 1966 |
Further studies on the stimulation of L-(14C)-amino acid incorporation with cycloheximide.
Topics: Aminopyrine; Aniline Compounds; Animals; Antifungal Agents; Antipyrine; Body Weight; Carbon Isotopes; Cycloheximide; Female; Growth; Hexobarbital; In Vitro Techniques; Liver; Magnesium; Microsomes; Organ Size; Phenylalanine; Proadifen; Rats; RNA; RNA, Messenger; Sleep; Sulfonamides | 1966 |
Impairment of hepatic drug metabolism in calcium deficiency.
Topics: Aminopyrine; Animals; Barbiturates; Benzoates; Hexobarbital; Hypocalcemia; Liver; Microsomes; Organ Size; Oxidation-Reduction; Rats | 1966 |
[Syndnones as inhibitors of biotransformation].
Topics: Aminopyrine; Animals; Biotransformation; Codeine; Hexobarbital; In Vitro Techniques; Liver; Microsomes; Oxadiazoles; Rats | 1966 |
Further studies on the metabolism of drugs by subfractions of hepatic microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzopyrenes; Codeine; Hexobarbital; In Vitro Techniques; Male; Microsomes; Mixed Function Oxygenases; Nitrobenzenes; Nitrogen; Oxidoreductases; Pigments, Biological; Rabbits; Rats; Sulfonamides; Transferases; Zoxazolamine | 1967 |
Hepatic microsomal activities in rats with long and short sleeping times after hexobarbital: a comparison.
Topics: Acetanilides; Aminopyrine; Animals; Biological Assay; Hexobarbital; In Vitro Techniques; Liver; Microsomes; Nitrobenzenes; Rats; Sleep | 1967 |
Effect of pretreatment of rabbits with phenobarbital or 3-methylcholanthrene on the distribution of drug-metabolizing enzyme activity in subfractions of hepatic microsomes.
Topics: Aminopyrine; Amphetamine; Animals; Benzopyrenes; Codeine; Hexobarbital; Liver; Male; Methylcholanthrene; Microscopy, Electron; Microsomes; Mixed Function Oxygenases; Phenobarbital; Pigments, Biological; Rabbits; Zoxazolamine | 1967 |
Sex differences in drug metabolism by rat liver microsomes.
Topics: Aminopyrine; Animals; Castration; Cytochromes; Female; Hexobarbital; Liver; Male; Microsomes; Oxidoreductases; Rats; Sex Characteristics; Spectrophotometry | 1967 |
Circadian rhythm in hepatic drug metabolizing activity in the rat.
Topics: Adrenalectomy; Aminopyrine; Animals; Circadian Rhythm; Female; Hexobarbital; Liver; Male; Nitrobenzenes; Rats | 1967 |
[Quantitative changes of rat's alpha 2 macroglobulin concentration by influence of carbon tetrachloride (author's transl)].
Topics: Alanine Transaminase; alpha-Macroglobulins; Aminopyrine; Animals; Body Weight; Carbon Tetrachloride Poisoning; Hexobarbital; Liver; Rats; Sleep; Time Factors | 1980 |
Comparison of hepatic drug-metabolizing enzymes induced by 3-methylcholanthrene and phenobarbital between pre- and postnatal rats.
Topics: Aminopyrine; Animals; Animals, Newborn; Benzo(a)pyrene; Benzopyrenes; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Fetus; Gestational Age; Hexobarbital; Maternal-Fetal Exchange; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Pregnancy; Rats; Rats, Inbred Strains | 1984 |
The excretion of ascorbic acid and hippuric acid in the urine of rats with liver injury.
Topics: Aminopyrine; Animals; Ascorbic Acid; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Female; Hexobarbital; Hippurates; Male; Rats; Sleep; Thioacetamide; Time Factors | 1980 |
Effect of doxapram on the action of other drugs and the hepatic drug-metabolizing system in mice.
Topics: Aminopyrine; Animals; Body Temperature; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Doxapram; Drug Interactions; Hexobarbital; Liver; Male; Mice; Pentobarbital; Sleep | 1982 |
Product inhibition during the hepatic microsomal N-demethylation of aminopyrine in the rat.
Topics: Aminopyrine; Animals; Binding, Competitive; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Glucosephosphate Dehydrogenase; Hexobarbital; In Vitro Techniques; Microsomes, Liver; Rats; Scintillation Counting; Spectrophotometry, Ultraviolet | 1981 |
[Inhibition of bacterial luminescence by cytochrome P-450 substrates].
Topics: Aminopyrine; Aniline Compounds; Cytochrome P-450 Enzyme System; Ethylmorphine; Hexobarbital; Kinetics; Luminescent Measurements; Morphine Derivatives; Photobacterium | 1981 |
Oxidation-reduction states of pyridine nucleotide and cytochrome P-450 during mixed-function oxidation in perfused rat liver.
Topics: Aminopyrine; Animals; Cytochrome P-450 Enzyme System; Hexobarbital; Kinetics; Liver; Male; Mixed Function Oxygenases; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Perfusion; Phenobarbital; Rats; Rats, Inbred Strains | 1981 |
[Effect of pyralgin on pharmacodynamics and kinetics of hexobarbital].
Topics: Adipose Tissue; Aminopyrine; Animals; Biological Availability; Brain; Dipyrone; Drug Synergism; Hexobarbital; Kinetics; Male; Rats; Rats, Inbred Strains; Sleep | 1981 |
The effect of cimetidine on in vitro and in vivo microsomal drug metabolism in the rat.
Topics: Aminopyrine; Animals; Cimetidine; Guanidines; Hexobarbital; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Pharmaceutical Preparations; Rats; Sleep; Time Factors | 1980 |
Stimulation of hepatic microsomal drug metabolism in the newborn and fetal rabbit.
Topics: Aminopyrine; Animals; Benzoates; Enzymes; Fetus; Hexobarbital; Liver; Rabbits | 1962 |
Stimulatory effects of chlordane on hepatic microsomal drug metabolism in the rat.
Topics: Aminopyrine; Animals; Chlordan; Chlorpromazine; Hexobarbital; Liver; Rats | 1963 |
[On cerebral polysynaptic reflexes in dogs and their modification by drugs].
Topics: Aminopyrine; Animals; Brain; Carisoprodol; Chlorpromazine; Dogs; Glutethimide; Hexobarbital; Hypnotics and Sedatives; Mephenesin; Morphine; Muscle Relaxants, Central; Reserpine; Tranquilizing Agents; Zoxazolamine | 1962 |
HYPERMOTILITY EVOKED BY LESIONS OF THE SEPTUM AND ANTERIOR HYPOTHALAMUS.
Topics: Aminopyrine; Amygdala; Atropine; Body Temperature; Caudate Nucleus; Cerebral Ventricles; Chlorpromazine; Electrocoagulation; Ephedrine; Hexobarbital; Hippocampus; Hypothalamus; Hypothalamus, Anterior; Imipramine; Iproniazid; Metabolism; Morphine; Movement Disorders; Physostigmine; Rats; Research; Reserpine; Scopolamine | 1963 |
P-AMINOSALICYLIC ACID INDUCED PROLONGATION OF HEXOBARBITAL SLEEPING TIME.
Topics: Aminopyrine; Aminosalicylic Acid; Aminosalicylic Acids; Codeine; Hexobarbital; Liver; Liver Glycogen; Metabolism; Pharmacology; Rats; Research; Sleep | 1963 |
THE METABOLISM OF DRUGS BY LIVER MICROSOMES FROM ALLOXAN-DIABETIC RATS: LONG TERM DIABETES.
Topics: Alloxan; Aminopyrine; Aniline Compounds; Animals; Codeine; Diabetes Mellitus, Experimental; Hexobarbital; Insulin; Liver; Liver Glycogen; Metabolism; Microsomes, Liver; Pharmacology; Phenobarbital; Rats; Research | 1963 |
EFFECTS OF ACUTE AND CHRONIC DDT ADMINISTRATION ON HEPATIC MICROSOMAL DRUG METABOLISM IN THE RAT.
Topics: Aminopyrine; Aniline Compounds; Chlordan; DDT; Hexobarbital; Insecticides; Liver; Metabolism; Nitrobenzenes; Organophosphate Poisoning; Pharmacology; Phosphorus; Poisons; Rats; Research | 1963 |
FACTORS AFFECTING HEPATIC MICROSOMAL ENZYME SYSTEMS INVOLVED IN DRUG METABOLISM.
Topics: Alloxan; Aminopyrine; Carcinoma, Hepatocellular; Chlordan; Chlorpromazine; Codeine; Hexobarbital; Jaundice; Jaundice, Obstructive; Liver; Liver Glycogen; Liver Neoplasms; Liver Regeneration; Microsomes; Phenobarbital; Portal System; Research; Starvation | 1963 |
THE EFFECTS OF NOREPINEPHRINE TREATMENT ON DRUG METABOLISM BY LIVER MICROSOMES FROM RATS.
Topics: Aminopyrine; Aniline Compounds; Carbohydrate Metabolism; Ergotamine; Glucosephosphate Dehydrogenase; Hexobarbital; Isoproterenol; Liver; Liver Glycogen; Metabolism; Microsomes; Microsomes, Liver; NADP; Norepinephrine; Pharmacology; Phenoxybenzamine; Rats; Research | 1964 |
SOME OF THE INTERACTIONS OF SKF 525-A WITH HEPATIC MICROSOMES.
Topics: Aminopyrine; Codeine; Dialysis; Fatty Acids; Hexobarbital; Iproniazid; Liver; Liver Glycogen; Metabolism; Microsomes; Microsomes, Liver; Proadifen; Rats; Renal Dialysis; Research | 1964 |
[DIFFERENCES IN MICROSOMAL OXIDATION AND ACETYLATION OF DRUGS IN DIFFERENT SPECIES AND RACES].
Topics: Acetylation; Aminopyrine; Dogs; Hexobarbital; Liver; Metabolism; Microsomes; Oxidation-Reduction; Pentobarbital; Rats; Research; Species Specificity; Thiopental; Toxicology | 1964 |
[ACCELERATED DRUG DEGRADATION BY ENZYME INDUCTION IN DOGS AFTER TREATMENT WITH PHENOBARBITAL].
Topics: Aminopyrine; Dogs; Enzyme Induction; Hexobarbital; Liver; Metabolism; Microsomes; Phenobarbital; Research; Toxicology | 1964 |
DIFFERENCES IN HEPATIC DRUG METABOLISM IN VARIOUS RABBIT STRAINS BEFORE AND AFTER PRETREATMENT WITH PHENOBARBITAL.
Topics: Aminopyrine; Amphetamine; Amphetamines; Aniline Compounds; Animals; Benzoates; Benzopyrenes; Chlorpromazine; Codeine; Hexobarbital; Liver; Metabolism; Phenobarbital; Rabbits; Research; Species Specificity; Transferases; Zoxazolamine | 1965 |
THE EFFECT OF CODEINE TOLERANCE ON HEPATIC MICROSOMAL DRUG METABOLISM IN THE RAT.
Topics: Aminopyrine; Aniline Compounds; Benzoates; Benzopyrenes; Chlorpromazine; Codeine; Drug Tolerance; Hexobarbital; Liver; Metabolism; Morphine; Rats; Research; Sulfonamides; Zoxazolamine | 1965 |
PROLONGATION OF HEXOBARBITAL SLEEPING TIME AND INHIBITION OF HEPATIC DRUG METABOLISM BY ADRENERGIC BLOCKING AGENTS IN MICE.
Topics: Adrenergic Antagonists; Aminopyrine; Aniline Compounds; Azepines; Body Temperature; Codeine; Hexobarbital; Hydralazine; Liver; Metabolism; Mice; Pharmacology; Phenols; Phenoxybenzamine; Phentolamine; Research; Sleep; Tolazoline; Yohimbine | 1965 |
THE STIMULATION OF DRUG METABOLISM IN VARIOUS RAT HEPATOMAS.
Topics: Aminopyrine; Aniline Compounds; Benzoates; Blood; Carcinoma, Hepatocellular; Chlordan; Hexobarbital; Liver; Liver Neoplasms; Metabolism; Neoplasms; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Pathology; Pharmacology; Phenobarbital; Rats; Research; Sulfanilamide; Sulfanilamides; Sulfonamides; Toxicology | 1965 |
[The acceleration of evipan oxidation and the demethylation of methylaminopyrine by barbiturates].
Topics: Acceleration; Aminopyrine; Barbiturates; Hexobarbital; Methylation; Oxidation-Reduction | 1959 |