hexamethonium has been researched along with substance p in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (44.59) | 18.7374 |
| 1990's | 32 (43.24) | 18.2507 |
| 2000's | 8 (10.81) | 29.6817 |
| 2010's | 1 (1.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berggren, A; Rubenson, A; Sillén, U | 1 |
| Koelbel, CB; Leduc, L; Mayer, EA; Snape, WJ; Vandeventer, G | 1 |
| Matsuo, S; Nakayama, S; Neya, T | 1 |
| Jin, JG; Nakayama, S; Takaki, M | 1 |
| Brown, DR; Hildebrand, KR | 1 |
| Ennes, H; Eysselein, V; Kodner, A; Koelbel, CB; Mayer, EA; Snape, WJ | 1 |
| Nakayama, S; Watanabe, Y; Yamasato, T | 1 |
| Nakayama, S; Takaki, M | 1 |
| Livett, BG; Zhou, XF | 1 |
| Chu, YH; Li, J | 1 |
| Ahlman, H; Dahlström, A; Lidberg, P | 1 |
| Delbro, D; Fändriks, L; Jönson, C | 1 |
| Hellström, PM | 1 |
| Costa, M; Furness, JB; Keast, JR | 1 |
| Elashoff, J; Khawaja, S; Mayer, EA; van Deventer, G; Walsh, JH | 1 |
| Burks, TF; Galligan, JJ | 1 |
| Buccafusco, JJ; Glisson, WC; Thomson, WM; Trimarchi, GR; VanLingen, J | 1 |
| Ahlman, J; Dahlstrom, A; Florence, L; Gronstad, K; Jaffe, BM; Zinner, MJ | 1 |
| Conte, B; Fanciullacci, M; Frilli, S; Furio, M; Geppetti, P; Giuliani, S; Maggi, CA; Meli, A; Santicioli, P | 1 |
| Isogaya, M; Ito, S; Nakazato, Y; Ohga, A; Sekine, H | 1 |
| Chahl, LA; Lynch, AM | 1 |
| Rozsa, Z; Varro, V | 1 |
| Mihara, S; Nishi, S; North, RA; Surprenant, A | 1 |
| Ahlman, H; Björck, S; Dahlstrand, C; Dahlström, A; Edin, R | 1 |
| Bornstein, JC; Costa, M; Furness, JB; Smith, TK | 1 |
| Jin, JG; Neya, T; Takaki, M | 1 |
| Koelbel, CB; Mayer, EA; Patel, A; Snape, WJ; van Deventer, G | 1 |
| Ahlman, H; Berggren, A; Dahlström, A; Rubenson, A; Sillén, U | 1 |
| Ho, FJ; Koelbel, CB; Mayer, EA; Patel, A; Reeve, JR; Snape, WJ | 1 |
| Jacobson, ED; Rozsa, Z | 1 |
| Holzer, P | 1 |
| Hou, JY; Otterson, MF; Sarna, SK | 1 |
| Barthó, L; Holzer, P; Leander, S; Lembeck, F | 1 |
| Daniel, EE; Fox, JE; Kostolanska, F; Manaka, H; Manaka, Y | 1 |
| Mizutani, M; Nakayama, S; Neya, T | 1 |
| Grider, JR | 1 |
| Booth, AM; de Groat, WC; Kawatani, M; Whitney, T | 1 |
| Brown, JC; Kwok, YN; McIntosh, CH; Pederson, RA | 1 |
| Grunstein, MM; Tanaka, DT | 1 |
| Gintzler, AR; Scalisi, JA | 1 |
| Collins, SM; Daniel, EE; Fox, AE; Fox, JE; Jury, J | 1 |
| Ahlman, H; Dahlström, A; Lidberg, P; Lundberg, JM | 1 |
| Hellström, PM; Jodal, M; Lundgren, O; Sjöqvist, A | 1 |
| Andersson, KE; Igawa, Y; Ishizuka, O; Mattiasson, A | 1 |
| Lin, KW; Liu, X | 1 |
| Drack, E; Halter, F; Scheurer, U | 1 |
| Barthó, L; Lefebvre, R | 1 |
| Cho, CH; Ko, JK; Tang, XL | 1 |
| Brunsson, I; Fahrenkrug, J; Jodal, M; Lundgren, O; Sjöqvist, A | 1 |
| Haga, N; Inatomi, N; Itoh, Z; Mizumoto, A; Shiba, Y; Yamamoto, O | 1 |
| Coupar, IM; Kerr, KP; Mitchelson, F | 1 |
| Kojima, S; Shimo, Y | 1 |
| Holzer, P; Maggi, CA; Schluet, W | 1 |
| Honda, H; Ito, S; Nakazato, Y; Ohga, A; Ohta, T | 1 |
| DeSautel, MG; Maher, JW; Sandler, AD; Schlegel, JF | 1 |
| Shinkai, M; Takayanagi, I | 1 |
| Ma, RC; Parkman, HP; Stapelfeldt, WH; Szurszewski, JH | 1 |
| De Giorgio, R; Giuliani, S; Lecci, A; Maggi, CA; Meini, S; Tramontana, M | 1 |
| Franks, CM; Hardcastle, J; Hardcastle, PT | 1 |
| Bornstein, JC; Furness, JB; Johnson, PJ; Yuan, SY | 1 |
| Farzin, D; Zarrindast, MR | 1 |
| Holst, JJ; Schmidt, PT | 1 |
| Condon, RE; Sarna, SK; Tsukamoto, M | 1 |
| Kuo, HC | 1 |
| Bossone, C; Goldhill, JM; Hosseini, JM; Piñeiro-Carrero, V; Shea-Donohue, T | 1 |
| Hornby, PJ; Krowicki, ZK | 1 |
| Berggreen, P; Ersbøll, AK; Grøndahl, ML; Hansen, MB; Maltbaek, JS; Skadhauge, E; Thorbøll, JE | 1 |
| Kim, D; Moore, BA; Vanner, S | 1 |
| Gao, C; Gao, N; Hu, HZ; Lin, Z; Liu, S; Ren, J; Wood, JD; Xia, Y | 1 |
| Ekström, J; Helander, HF | 1 |
| Bergquist, J; Svensson, L; Wennerås, C | 1 |
| Hancock, JC; Hoover, DB; Zhang, L | 1 |
| Ardell, JL; Hoover, DB; Parsons, RL; Tompkins, JD | 1 |
| Andersson, DA; Bevan, S; Bodkin, JV; Brain, SD; Graepel, R; Pozsgai, G | 1 |
74 other study(ies) available for hexamethonium and substance p
| Article | Year |
|---|---|
Involvement of opioid mechanisms in peripheral motor control of detrusor muscle.
Topics: Animals; Electric Stimulation; Enkephalins; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Humans; Indoles; Male; Morphinans; Morphine; Muscle Contraction; Muscles; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Substance P; Sympatholytics | 1992 |
Neurokinin inhibition of cholinergic myenteric neurons in canine antrum.
Topics: Acetylcholine; Animals; Atropine; Dinoprostone; Dogs; Electric Stimulation; Enkephalin, Methionine; Female; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth; Myenteric Plexus; Naloxone; Neurokinin A; Neurons; Nifedipine; Phentolamine; Propranolol; Pyloric Antrum; Substance P; Tetrodotoxin; Vasoactive Intestinal Peptide | 1990 |
Intrinsic reflexes mediated via peptidergic neurons in the smooth muscle esophagus of the hen.
Topics: Animals; Atropine; Capsaicin; Chickens; Electric Stimulation; Esophagus; Female; Hexamethonium; Hexamethonium Compounds; Muscle, Smooth; Myenteric Plexus; Naloxone; Neurons; Neuropeptides; Peristalsis; Reflex; Substance P | 1990 |
Capsaicin-sensitive and hexamethonium-insensitive circular muscle responses to mesenteric nerve stimulation in the isolated guinea pig ileum.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Female; Gastrointestinal Motility; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Ileum; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Substance P | 1990 |
Intrinsic neuroregulation of ion transport in porcine distal jejunum.
Topics: Acetylcholine; Animals; Biological Transport; Electric Stimulation; Electrolytes; Female; Hexamethonium; Hexamethonium Compounds; Jejunum; Male; Mollusk Venoms; Neurons; omega-Conotoxin GVIA; Parasympatholytics; Substance P; Swine; Tetrodotoxin; Vasoactive Intestinal Peptide | 1990 |
Substance P and CGRP mediate motor response of rabbit colon to capsaicin.
Topics: Acetylcholine; Adenosine Triphosphate; Afferent Pathways; Animals; Atropine; Calcitonin Gene-Related Peptide; Capsaicin; Colon; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Kinetics; Male; Muscle, Smooth; Neurons; Rabbits; Substance P; Tetrodotoxin | 1990 |
Neural regulation of the interrelation between haustral and taenial motility in the rabbit proximal colon.
Topics: Animals; Atropine; Autonomic Agents; Capsaicin; Colon; Electric Stimulation; Female; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Neurons; Peptides; Rabbits; Serotonin; Substance P | 1990 |
Electrical behavior of myenteric neurons induced by mesenteric nerve stimulation in the guinea pig ileum.
Topics: Animals; Calcium; Capsaicin; Electric Stimulation; Electrophysiology; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Ileum; Magnesium; Mesentery; Myenteric Plexus; Nervous System Physiological Phenomena; Neurons; Substance P | 1990 |
Substance P has biphasic effects on catecholamine secretion evoked by electrical stimulation of perfused rat adrenal glands in vitro.
Topics: Adrenal Glands; Animals; Atropine; Choline; Electric Stimulation; Epinephrine; Female; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Norepinephrine; Perfusion; Rats; Rats, Inbred BUF; Substance P; Time Factors | 1990 |
Drug responses in antigen-induced contractions of tracheal strips of ovalbumin-sensitized guinea pigs.
Topics: Animals; Atropine; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; Substance P; Trachea | 1990 |
On the nature of the contractile motor responses of the rat stomach elicited by serotonin or substance P in vitro.
Topics: Animals; Atropine; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Stomach; Substance P; Tachyphylaxis; Tetrodotoxin | 1985 |
Blockade of substance P receptors inhibits non-nicotinic, non-adrenergic colonic contractions induced by stimulation of the lumbar sympathetic nerves to the feline large intestine.
Topics: Acetylcholine; Animals; Cats; Colon; Electric Stimulation; Female; Gastrointestinal Motility; Guanethidine; Heparin; Hexamethonium; Hexamethonium Compounds; Hydrocortisone; Intestine, Large; Male; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Sympathetic Nervous System; Tachyphylaxis | 1985 |
Pharmacological analysis of the mechanism of action for colonic contraction induced by neurotensin, substance P and methionine-enkephalin.
Topics: Animals; Atropine; Cats; Colon; Enkephalin, Methionine; Gastrointestinal Motility; Guanethidine; Hexamethonium; Hexamethonium Compounds; Neurotensin; Phentolamine; Propranolol; Somatostatin; Substance P; Tetrodotoxin | 1985 |
Investigations of nerve populations influencing ion transport that can be stimulated electrically, by serotonin and by a nicotinic agonist.
Topics: Animals; Biological Transport; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Electrolytes; Female; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Intestinal Mucosa; Male; Neurons; Piperazines; Scopolamine; Serotonin; Substance P; Tetrodotoxin | 1985 |
Characterization of substance P effects on canine antral muscle.
Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Dogs; Dose-Response Relationship, Drug; Extracellular Space; Female; Hexamethonium; Hexamethonium Compounds; Male; Muscle Contraction; Pyloric Antrum; Substance P; Tetrodotoxin; Time Factors | 1986 |
Cholinergic neurons mediate intestinal propulsion in the rat.
Topics: Animals; Atropine; Female; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Intestines; Muscle Contraction; Neostigmine; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Substance P | 1986 |
Cholinergic neurons and the cardiovascular response produced by central injection of substance P in the normotensive rat.
Topics: Animals; Atropine; Blood Pressure; Brain; Cholinergic Fibers; Heart Rate; Hemicholinium 3; Hexamethonium; Hexamethonium Compounds; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Substance P | 1986 |
Regulatory mechanisms in endoluminal release of serotonin and substance P from feline jejunum.
Topics: Animals; Atropine; Cats; Electric Stimulation; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Isoproterenol; Jejunum; Male; Propranolol; Receptors, Adrenergic; Receptors, Cholinergic; Serotonin; Substance P; Vagus Nerve | 1987 |
The contribution of capsaicin-sensitive innervation to activation of the spinal vesico-vesical reflex in rats: relationship between substance P levels in the urinary bladder and the sensory-efferent function of capsaicin-sensitive sensory neurons.
Topics: Animals; Blood Pressure; Capsaicin; Decerebrate State; Heart Rate; Hexamethonium; Hexamethonium Compounds; Male; Muscle Contraction; Neurons, Afferent; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Substance P; Time Factors; Urinary Bladder | 1987 |
Atropine- and hexamethonium-resistant motor response to greater splanchnic nerve stimulation in the dog stomach.
Topics: Animals; Atropine; Dogs; Female; Gastrointestinal Motility; Guanethidine; Hexamethonium; Hexamethonium Compounds; Male; Motor Neurons; Phenoxybenzamine; Pyrilamine; Splanchnic Nerves; Stomach; Substance P | 1987 |
The acute effects of capsaicin on the cardiovascular system.
Topics: Animals; Blood Pressure; Capsaicin; Cardiovascular Physiological Phenomena; Cardiovascular System; Denervation; Heart Rate; Hexamethonium; Hexamethonium Compounds; Male; Morphine; Rats; Rats, Inbred Strains; Substance P; Vagus Nerve | 1987 |
Mechanism of "substance P": on mesenteric blood flow; interactions with opioid peptides.
Topics: Acetylcholine; Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Endorphins; Female; Hexamethonium; Hexamethonium Compounds; Lactates; Lactic Acid; Male; Naloxone; Oxygen Consumption; Splanchnic Circulation; Substance P | 1987 |
A non-adrenergic, non-cholinergic slow inhibitory post-synaptic potential in neurones of the guinea-pig submucous plexus.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Dioxanes; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Idazoxan; In Vitro Techniques; Nerve Fibers; Neurons; Potassium; Receptors, Adrenergic; Receptors, Nicotinic; Submucous Plexus; Substance P; Synapses; Time Factors | 1987 |
Substance P in the control of extrahepatic biliary motility in the cat.
Topics: Animals; Atropine; Axons; Bile; Cats; Electric Stimulation; Gallbladder; Hexamethonium; Hexamethonium Compounds; Substance P; Vagus Nerve | 1988 |
An electrophysiological study of the projections of motor neurones that mediate non-cholinergic excitation in the circular muscle of the guinea-pig small intestine.
Topics: Action Potentials; Animals; Apamin; Electrophysiology; Female; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Intestine, Small; Male; Motor Neurons; Muscle, Smooth; Neuromuscular Junction; Nicardipine; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Recombinant Proteins; Substance P; Synaptic Transmission | 1988 |
Polar innervation of enteric non-cholinergic and non-adrenergic neurons in the isolated guinea-pig ileum.
Topics: Animals; Efferent Pathways; Electric Stimulation; Female; Guanethidine; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Myenteric Plexus; Neurons; Substance P | 1988 |
Characterization of the effects of neurokinins on canine antral muscle.
Topics: Acetylcholine; Animals; Atropine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dogs; Female; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Pyloric Antrum; Reference Values; Substance P; Tetrodotoxin | 1988 |
In vivo motor effects of substance P on the rat urinary bladder.
Topics: Animals; Atropine; Electric Stimulation; Hexamethonium; Hexamethonium Compounds; Injections, Intra-Arterial; Male; Motor Neurons; Muscle Contraction; Peptide Fragments; Rats; Rats, Inbred Strains; Substance P; Urinary Bladder | 1988 |
Involvement of substance P in noncholinergic excitation of rabbit colonic muscle.
Topics: Acetylcholine; Animals; Atropine; Calcium; Colon; Electric Stimulation; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Male; Muscle Contraction; Neurokinin A; Neurokinin B; Rabbits; Substance P | 1989 |
Capsaicin-sensitive nerves are involved in bile-oleate-induced intestinal hyperemia.
Topics: Animals; Atropine; Bile; Blood Pressure; Capsaicin; Female; Heart Rate; Hexamethonium; Hexamethonium Compounds; Hyperemia; Immune Sera; Jejunum; Male; Mesenteric Arteries; Oleic Acid; Oleic Acids; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow; Reserpine; Sincalide; Splanchnic Circulation; Substance P; Vasoactive Intestinal Peptide | 1989 |
Ascending enteric reflex: multiple neurotransmitter systems and interactions.
Topics: Analgesics; Animals; Atropine; Female; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Ileum; In Vitro Techniques; Jejunum; Male; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Reflex; Substance P; Tetrodotoxin | 1989 |
Local effect of substance P on colonic motor activity in different experimental states.
Topics: Animals; Atropine; Colon; Dogs; Female; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Male; Muscle, Smooth; Substance P; Tetrodotoxin | 1989 |
Evidence for an involvement of substance P, but not cholecystokinin-like peptides, in hexamethonium-resistant intestinal peristalsis.
Topics: Animals; Cholecystokinin; Drug Resistance; Female; Ganglionic Blockers; Gastrointestinal Motility; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Naloxone; Peptides; Peristalsis; Substance P; Tetrodotoxin | 1989 |
Release of VIP and substance P from isolated perfused canine ileum.
Topics: Animals; Atropine; Chromatography, Gel; Chromatography, High Pressure Liquid; Dogs; Dynorphins; Electric Stimulation; Enkephalin, Methionine; Female; Hexamethonium; Hexamethonium Compounds; Ileum; In Vitro Techniques; Kinetics; Male; Peptide Fragments; Perfusion; Radioimmunoassay; Substance P; Tetrodotoxin; Vasoactive Intestinal Peptide | 1989 |
Involvement of substance P neurons in contractions of canine small intestine produced by mesenteric nerve stimulation.
Topics: Adrenergic Fibers; Animals; Atropine; Cholinergic Fibers; Dogs; Electric Stimulation; Female; Hexamethonium; Hexamethonium Compounds; Intestine, Small; Male; Muscle Contraction; Muscle, Smooth; Substance P; Sympathectomy; Vagus Nerve | 1989 |
Identification of neurotransmitters regulating intestinal peristaltic reflex in humans.
Topics: Atropine; Ganglionic Blockers; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Humans; In Vitro Techniques; Jejunum; Motor Neurons; Neurokinin A; Neurotransmitter Agents; Peristalsis; Substance P; Tetrodotoxin; Vasoactive Intestinal Peptide | 1989 |
Excitatory effect of substance P in parasympathetic ganglia of cat urinary bladder.
Topics: Animals; Atropine; Cats; Enkephalin, Leucine; Evoked Potentials; Female; gamma-Aminobutyric Acid; Ganglia, Parasympathetic; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Substance P; Synaptic Transmission; Urinary Bladder | 1989 |
Effect of substance P on somatostatin release from the isolated perfused rat stomach.
Topics: Animals; Atropine; Gastric Mucosa; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Male; Naloxone; Perfusion; Rats; Rats, Inbred Strains; Somatostatin; Stomach; Substance P | 1985 |
Mechanisms of substance P-induced contraction of rabbit airway smooth muscle.
Topics: Animals; Atropine; Biomechanical Phenomena; Dose-Response Relationship, Drug; Ganglia, Parasympathetic; Hemicholinium 3; Hexamethonium; Hexamethonium Compounds; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Neostigmine; Nerve Block; Neural Inhibition; Rabbits; Substance P; Synaptic Transmission; Tetrodotoxin; Trachea | 1984 |
Effects of opioids on noncholinergic excitatory responses of the guinea-pig isolated ileum: inhibition of release of enteric substance P.
Topics: Animals; Electric Stimulation; Endorphins; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Substance P | 1982 |
Sites and mechanisms of action of neuropeptides on canine gastric motility differ in vivo and in vitro.
Topics: Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Gastrointestinal Hormones; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Motilin; Muscle Contraction; Pentagastrin; Stomach; Substance P; Tetrodotoxin | 1983 |
Different modes of action of substance P in the motor control of the feline stomach and pylorus.
Topics: Animals; Atropine; Blood Pressure; Cats; Electric Stimulation; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Hot Temperature; Pylorus; Stomach; Substance P; Vagus Nerve | 1983 |
Neurotransmitters involved in the colonic contraction and vasodilatation elicited by activation of the pelvic nerves in the cat.
Topics: Animals; Atropine; Cats; Colon; Enkephalin, Methionine; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Neurotransmitter Agents; Receptors, Cell Surface; Receptors, Neurokinin-1; Substance P; Vasodilation | 1984 |
Capsaicin-induced bladder hyperactivity in normal conscious rats.
Topics: Administration, Intravesical; Animals; Benzamides; Capsaicin; Consciousness; Dose-Response Relationship, Drug; Female; Hexamethonium; Hexamethonium Compounds; Indoles; Isoindoles; Morphine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Substance P; Urinary Bladder | 1994 |
[Effect and its mechanism of substance P on contractile activity of isolated antral muscle strips of rat].
Topics: Animals; Cyproheptadine; Diphenhydramine; Dose-Response Relationship, Drug; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Stomach; Substance P | 1994 |
Substance P activates rat colonic motility via excitatory and inhibitory neural pathways and direct action on muscles.
Topics: Animals; Colon; Dose-Response Relationship, Drug; Gastrointestinal Motility; Hexamethonium; In Vitro Techniques; Male; Muscle, Smooth; Neural Inhibition; Nitric Oxide; Rats; Rats, Wistar; Substance P; Tetrodotoxin; Vasoactive Intestinal Peptide | 1994 |
Nitric oxide induces acetylcholine-mediated contractions in the guinea-pig small intestine.
Topics: Acetylcholine; Animals; Atropine; Biphenyl Compounds; Dose-Response Relationship, Drug; Guinea Pigs; Hexamethonium; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Substance P; Tetrodotoxin | 1994 |
The differential mechanisms of mild irritants on adaptive cytoprotection.
Topics: Adaptation, Physiological; Animals; Arginine; Atropine; Capsaicin; Chorionic Gonadotropin; Ethanol; Gastric Mucosa; Hexamethonium; Indomethacin; Irritants; Lidocaine; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Stomach Ulcer; Substance P | 1994 |
Substance P effects on blood flow, fluid transport and vasoactive intestinal polypeptide release in the feline small intestine.
Topics: Animals; Biological Transport; Body Fluids; Cats; Electric Stimulation; Enkephalin, Methionine; Female; Hexamethonium; Indomethacin; Intestine, Small; Male; Regional Blood Flow; Splanchnic Nerves; Substance P; Vasoactive Intestinal Peptide | 1995 |
Stimulatory mechanism of EM523-induced contractions in postprandial stomach of conscious dogs.
Topics: Animals; Anti-Bacterial Agents; Atropine; Dipeptides; Dogs; Dopamine; Eating; Erythromycin; Hexamethonium; Indoles; Motilin; Muscle Contraction; Naloxone; Ondansetron; Serotonin Antagonists; Stomach; Substance P | 1995 |
Vagal nerve stimulation of the guinea-pig oesophagus.
Topics: Animals; Atropine; Calcium Channel Blockers; Capsaicin; Electric Stimulation; Esophagus; Ganglionic Blockers; Guinea Pigs; Hexamethonium; In Vitro Techniques; Male; omega-Conotoxin GVIA; Peptides; Physostigmine; Substance P; Thiorphan; Tubocurarine; Vagus Nerve | 1995 |
Calcitonin gene-related peptide (CGRP)-enhanced non-adrenergic non-cholinergic contraction of guinea-pig proximal colon.
Topics: Animals; Atropine; Calcitonin Gene-Related Peptide; Colon; Electric Stimulation; Guanethidine; Guinea Pigs; Hexamethonium; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Receptors, Adrenergic; Receptors, Cholinergic; Serotonin; Substance P | 1995 |
Ascending enteric reflex contraction: roles of acetylcholine and tachykinins in relation to distension and propagation of excitation.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Atropine; Cholinergic Antagonists; Female; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Ileum; In Vitro Techniques; Isometric Contraction; Isotonic Contraction; Jejunum; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Physalaemin; Receptors, Neurotransmitter; Receptors, Tachykinin; Reflex; Substance P; Synaptic Transmission; Tachykinins | 1993 |
Gastric vasodilator and motor responses to splanchnic stimulation and tachykinins in the dog.
Topics: Animals; Calcitonin Gene-Related Peptide; Dogs; Electric Stimulation; Female; Hexamethonium; Hexamethonium Compounds; Male; Muscle Contraction; Regional Blood Flow; Splanchnic Nerves; Stomach; Substance P; Tachykinins; Vascular Resistance; Vasodilation | 1993 |
Neuroregulation of a chemosensitive afferent system in the canine distal esophagus.
Topics: Afferent Pathways; Animals; Atropine; Blood Pressure; Capsaicin; Chemoreceptor Cells; Dogs; Esophagus; Hexamethonium; Hexamethonium Compounds; Mucous Membrane; Nociceptors; Piperidines; Pressure; Pulse; Respiration; Substance P; Tetrodotoxin; Vagotomy | 1993 |
Effect of tachykinins on the acetylcholine output stimulated by nicotine from guinea-pig bladder.
Topics: Acetylcholine; Animals; Female; Guanethidine; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Kinetics; Muscle Contraction; Muscle, Smooth; Nicotine; Receptors, Tachykinin; Substance P; Tachykinins; Tetrodotoxin; Urinary Bladder | 1993 |
Direct and indirect mechanosensory pathways from the colon to the inferior mesenteric ganglion.
Topics: Acetylcholine; Afferent Pathways; Animals; Atropine; Colon; Electrophysiology; Ganglia, Sympathetic; Ganglionic Blockers; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Male; Mechanoreceptors; Physical Stimulation; Substance P; Tubocurarine; Vasoactive Intestinal Peptide | 1993 |
In vivo evidence for the involvement of tachykinin NK3 receptors in the hexamethonium-resistant inhibitory transmission in the rat colon.
Topics: Adrenergic Agents; Animals; Colon; Dose-Response Relationship, Drug; Guanethidine; Hexamethonium; Male; Muscle Contraction; Neurokinin A; NG-Nitroarginine Methyl Ester; Nicotinic Antagonists; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P | 1996 |
Neural involvement in 5-hydroxytryptamine-induced net electrogenic ion secretion in the rat intestine in-vivo.
Topics: Acetylcholine; Animals; Atropine; Cholinergic Antagonists; Colon; Dinoprostone; Electrophysiology; Hexamethonium; Ileum; Intestinal Mucosa; Intestines; Ion Channels; Jejunum; Male; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists; Substance P | 1996 |
Analysis of contributions of acetylcholine and tachykinins to neuro-neuronal transmission in motility reflexes in the guinea-pig ileum.
Topics: Acetylcholine; Afferent Pathways; Animals; Efferent Pathways; Female; Gastrointestinal Motility; Guinea Pigs; Hexamethonium; Ileum; Male; Membrane Potentials; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nicotinic Antagonists; Peptide Fragments; Receptors, Neurokinin-3; Reflex; Scopolamine; Substance P; Synaptic Transmission; Tachykinins | 1996 |
Nicotine attenuates naloxone-induced jumping behaviour in morphine-dependent mice.
Topics: Animals; Atropine; Behavior, Animal; Benzazepines; Hexamethonium; Male; Mecamylamine; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; Nicotine; Phenoxybenzamine; Propranolol; Substance P; Substance Withdrawal Syndrome; Sulpiride | 1996 |
Use of antagonists to define tachykininergic control of intestinal motility in pigs.
Topics: Animals; Atropine; Capsaicin; Electric Stimulation; Gastrointestinal Motility; Hexamethonium; Ileum; In Vitro Techniques; Neurokinin A; Perfusion; Phentolamine; Substance P; Swine; Tachykinins | 1997 |
A novel motility effect of tachykinins in normal and inflamed colon.
Topics: Animals; Atropine; Colon; Dogs; Female; Hexamethonium; Inflammation; Infusions, Intra-Arterial; Male; Muscle Contraction; Muscle, Smooth; Myoelectric Complex, Migrating; Receptors, Tachykinin; Substance P; Tetrodotoxin | 1997 |
Inhibitory effect of capsaicin on detrusor contractility: further study in the presence of ganglionic blocker and neurokinin receptor antagonist in the rat urinary bladder.
Topics: Administration, Intravesical; Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Ganglionic Blockers; Hexamethonium; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Substance P; Urinary Bladder | 1997 |
Progressive alterations in circular smooth muscle contractility in TNBS-induced colitis in rats.
Topics: Acetylcholine; Animals; Atropine; Colitis; Dose-Response Relationship, Drug; Gastrointestinal Motility; Hexamethonium; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Nicotinic Antagonists; Parasympatholytics; Potassium Chloride; Rats; Rats, Sprague-Dawley; Substance P; Tetrodotoxin; Trinitrobenzenesulfonic Acid; Vasodilator Agents | 1999 |
Substance P in the dorsal motor nucleus of the vagus evokes gastric motor inhibition via neurokinin 1 receptor in rat.
Topics: Animals; Ganglionic Blockers; Gastric Fundus; Gastrointestinal Motility; Hemodynamics; Hexamethonium; Male; Microinjections; Motor Neurons; Neural Pathways; Neurokinin-1 Receptor Antagonists; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Vagotomy; Vagus Nerve | 2000 |
Regional differences in neurogenic signal transduction pathway of cholera toxin-induced fluid, electrolyte and serotonin accumulation in the porcine jejunum.
Topics: Animals; Body Fluids; Cholera Toxin; Dose-Response Relationship, Drug; Electrolytes; Female; Hexamethonium; Jejunum; Nicotinic Antagonists; Ondansetron; Piperidines; Receptors, Neurokinin-1; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Signal Transduction; Substance P; Swine | 2000 |
Neural pathways regulating Brunner's gland secretion in guinea pig duodenum in vitro.
Topics: Animals; Brunner Glands; Capsaicin; Carbachol; Choline O-Acetyltransferase; Cholinergic Agonists; Cholinergic Fibers; Dimethylphenylpiperazinium Iodide; Duodenum; Electric Stimulation; Female; Ganglia, Sympathetic; Guanethidine; Guinea Pigs; Hexamethonium; In Vitro Techniques; Male; Muscarinic Antagonists; Neural Pathways; Neurotransmitter Agents; Nicotinic Agonists; Nicotinic Antagonists; Piperidines; Submucous Plexus; Substance P; Sympatholytics; Tetrodotoxin; Vagotomy; Vagus Nerve | 2000 |
Chemical coding and electrophysiology of enteric neurons expressing neurofilament 145 in guinea pig gastrointestinal tract.
Topics: Action Potentials; Animals; Axons; Calbindin 2; Calbindins; Digestive System; Enteric Nervous System; Excitatory Postsynaptic Potentials; Guinea Pigs; Hexamethonium; Immunohistochemistry; Male; Myenteric Plexus; Neurofilament Proteins; Neurons; Neuropeptide Y; Nitric Oxide Synthase; Receptors, Neurokinin-1; S100 Calcium Binding Protein G; Serotonin; Somatostatin; Submucous Plexus; Substance P; Vasoactive Intestinal Peptide | 2002 |
Secretion from submucosal salivary glands of the ferret in response to a cholinesterase inhibitor applied onto the oral mucosa.
Topics: Administration, Buccal; Animals; Atropine; Blood Pressure; Cholinesterase Inhibitors; Female; Ferrets; Ganglionic Blockers; Hexamethonium; Lip; Models, Animal; Mouth Mucosa; Muscarinic Antagonists; Neurotransmitter Agents; Parotid Gland; Pharmaceutical Vehicles; Physostigmine; Salivary Glands, Minor; Secretory Rate; Statistics as Topic; Submandibular Gland; Substance P; Time Factors | 2002 |
Neuromodulation of experimental Shigella infection reduces damage to the gut mucosa.
Topics: Animals; Calcitonin Gene-Related Peptide; Dysentery, Bacillary; Galanin; Hexamethonium; Inflammation; Intestinal Mucosa; Intestine, Small; Motilin; Neuropeptides; Neurotensin; Nicotinic Antagonists; Peptide YY; Rabbits; Shigella flexneri; Somatostatin; Substance P; Vasoactive Intestinal Peptide | 2004 |
Tachykinin agonists modulate cholinergic neurotransmission at guinea-pig intracardiac Ganglia.
Topics: Acetylcholine; Action Potentials; Animals; Electric Stimulation; Ganglia, Parasympathetic; Guinea Pigs; Hexamethonium; Male; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Synaptic Transmission | 2005 |
Neurally released pituitary adenylate cyclase-activating polypeptide enhances guinea pig intrinsic cardiac neurone excitability.
Topics: Animals; Atropine; Autonomic Fibers, Preganglionic; Electric Stimulation; Excitatory Postsynaptic Potentials; Ganglia, Parasympathetic; Guinea Pigs; Heart; Heart Atria; Hexamethonium; In Vitro Techniques; Kinetics; Muscarinic Antagonists; Neurons; Nicotinic Antagonists; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Muscarinic; Receptors, Nicotinic; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; Substance P; Synaptic Transmission | 2007 |
Evidence for the pathophysiological relevance of TRPA1 receptors in the cardiovascular system in vivo.
Topics: Acrolein; Adrenergic alpha-1 Receptor Antagonists; Animals; Atropine; Blood Pressure; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Female; Ganglionic Blockers; Heart Rate; Hemodynamics; Hexamethonium; Isothiocyanates; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Muscarinic Antagonists; Prazosin; Regional Blood Flow; Skin; Substance P; Time Factors; Transient Receptor Potential Channels; TRPA1 Cation Channel; Vasodilation | 2010 |