hexahydrodifenidol has been researched along with dicyclomine in 1 studies
*Dicyclomine: A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms. [MeSH]
*Dicyclomine: A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms. [MeSH]
| Studies (hexahydrodifenidol) | Trials (hexahydrodifenidol) | Recent Studies (post-2010) (hexahydrodifenidol) | Studies (dicyclomine) | Trials (dicyclomine) | Recent Studies (post-2010) (dicyclomine) |
|---|---|---|---|---|---|
| 11 | 0 | 0 | 398 | 41 | 74 |
| Protein | Taxonomy | hexahydrodifenidol (IC50) | dicyclomine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.468 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.046 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.0029 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.0024 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.0035 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.0044 | |
| Histamine H2 receptor | Homo sapiens (human) | 1.625 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.24 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.468 | |
| D(3) dopamine receptor | Homo sapiens (human) | 1.21 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 1.301 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 3.065 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.0049 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonner, TI; Brann, MR; Buckley, CM; Buckley, NJ | 1 |
1 other study(ies) available for hexahydrodifenidol and dicyclomine
| Article | Year |
|---|---|
Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells.
Topics: Animals; Cell Line; Cloning, Molecular; Cricetinae; Humans; Kinetics; N-Methylscopolamine; Parasympatholytics; Rats; Receptors, Muscarinic; Scopolamine Derivatives | 1989 |