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hexachlorobutadiene and cysteine

hexachlorobutadiene has been researched along with cysteine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19909 (64.29)18.7374
1990's5 (35.71)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anders, MW; Dekant, W; Vamvakas, S1
Lock, EA; Schnellmann, RG1
Dekant, W; Henschler, D; Müller, DA; Vamvakas, S1
Berthold, K; Dekant, W; Henschler, D; Vamvakas, S1
Dekant, W; Henschler, D; Kordowich, FJ; Neudecker, T; Vamvakas, S1
Dekant, W; Henschler, D; Schrenk, D1
Berthold, K; Dekant, W; Henschler, D; Schmidt, S; Vamvakas, S; Wild, D1
Lock, EA; Mandel, LJ; Schnellmann, RG1
Lock, EA; Odum, J; Ormond, P1
Berndt, WO; Davis, ME; Mehendale, HM1
Ishmael, J; Lock, EA1
Bouthillier, L; Brodeur, J; Charbonneau, M1
Anders, MW; Finkelstein, MB; Lock, EA; Moore, RB; Sani, Y; Seawright, AA1
Birner, G; Dekant, W; Mehler, C; Rosner, E; Werner, M1

Reviews

1 review(s) available for hexachlorobutadiene and cysteine

ArticleYear
Bioactivation of hexachlorobutadiene by glutathione conjugation.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1990, Volume: 28, Issue:4

    Topics: Animals; Biotransformation; Butadienes; Cysteine; Glutathione; Kidney Diseases; Liver

1990

Other Studies

13 other study(ies) available for hexachlorobutadiene and cysteine

ArticleYear
The effect of haloalkene cysteine conjugates on rat renal glutathione reductase and lipoyl dehydrogenase activities.
    Toxicology and applied pharmacology, 1990, Jun-01, Volume: 104, Issue:1

    Topics: Animals; Butadienes; Cysteine; Cytosol; Dihydrolipoamide Dehydrogenase; Female; Fluorocarbons; Glutathione Reductase; Kidney; Kidney Cortex; Liver; Male; Mitochondria; Rats; Trichloroethylene

1990
DNA-binding of sulfur-containing metabolites from 35S-(pentachlorobutadienyl)-L-cysteine in bacteria and isolated renal tubular cells.
    Drug metabolism and drug interactions, 1988, Volume: 6, Issue:3-4

    Topics: Animals; Bacteria; Butadienes; Chromatography, High Pressure Liquid; Cysteine; DNA; DNA, Bacterial; In Vitro Techniques; Kidney Neoplasms; Kidney Tubules; Male; Rats; Rats, Inbred Strains; Salmonella typhimurium; Spectrophotometry, Ultraviolet; Sulfur; Sulfur Radioisotopes

1988
Thioacylating agents as ultimate intermediates in the beta-lyase catalysed metabolism of S-(pentachloro-butadienyl)-L-cysteine.
    Chemico-biological interactions, 1988, Volume: 67, Issue:1-2

    Topics: Butadienes; Carbon-Sulfur Lyases; Chromatography, High Pressure Liquid; Cysteine; Gas Chromatography-Mass Spectrometry; Lyases; Mass Spectrometry; Molecular Structure; Pyridoxal

1988
Mutagenicity of hexachloro-1,3-butadiene and its S-conjugates in the Ames test--role of activation by the mercapturic acid pathway in its nephrocarcinogenicity.
    Carcinogenesis, 1988, Volume: 9, Issue:6

    Topics: Aminooxyacetic Acid; Animals; Biotransformation; Butadienes; Cysteine; Cytosol; Fungicides, Industrial; Glutathione; Kidney; Kidney Neoplasms; Microsomes; Microsomes, Liver; Mitochondria; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium

1988
Metabolism and excretion of S-conjugates derived from hexachlorobutadiene in the isolated perfused rat kidney.
    Molecular pharmacology, 1988, Volume: 34, Issue:3

    Topics: Acetylation; Animals; Butadienes; Cysteine; Female; Glutathione; Kidney; Perfusion; Probenecid; Rats; Rats, Inbred Strains

1988
Bacterial beta-lyase mediated cleavage and mutagenicity of cysteine conjugates derived from the nephrocarcinogenic alkenes trichloroethylene, tetrachloroethylene and hexachlorobutadiene.
    Chemico-biological interactions, 1986, Oct-15, Volume: 60, Issue:1

    Topics: Animals; Biotransformation; Butadienes; Carbon-Sulfur Lyases; Cysteine; Kidney; Lyases; Male; Microsomes; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Rats; Rats, Inbred Strains; Salmonella typhimurium; Structure-Activity Relationship; Tetrachloroethylene; Trichloroethylene

1986
A mechanism of S-(1,2,3,4,4-pentachloro-1,3-butadienyl)-L-cysteine toxicity to rabbit renal proximal tubules.
    Toxicology and applied pharmacology, 1987, Sep-30, Volume: 90, Issue:3

    Topics: Animals; Butadienes; Cysteine; Dose-Response Relationship, Drug; Female; Glutathione; In Vitro Techniques; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Rabbits

1987
Transport of N-acetyl-S-pentachloro-1,3-butadienylcysteine by rat renal cortex.
    Archives of toxicology, 1986, Volume: 59, Issue:1

    Topics: Acetylcysteine; Animals; Antimetabolites; Biological Transport, Active; Butadienes; Cysteine; Female; Kidney Cortex; Kinetics; Rats; Rats, Inbred Strains; Temperature

1986
Effects of cysteine and diethylmaleate pretreatments on renal function and response to a nephrotoxicant.
    Archives of toxicology, 1986, Volume: 59, Issue:1

    Topics: Animals; Blood Urea Nitrogen; Butadienes; Cysteine; Glycosuria; Kidney Diseases; Male; Maleates; Proteinuria; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Time Factors

1986
Nephrotoxicity of hexachlorobutadiene and its glutathione-derived conjugates.
    Toxicologic pathology, 1986, Volume: 14, Issue:2

    Topics: Acetylcysteine; Animals; Butadienes; Cysteine; Female; Glutathione; Kidney Diseases; Kidney Medulla; Kidney Tubules, Proximal; Male; Necrosis; Rats; Sex Factors; Urea

1986
Assessment of the role of glutathione conjugation in the protection afforded by anethol dithiolthione against hexachloro-1,3-butadiene-induced nephrotoxicity.
    Toxicology and applied pharmacology, 1996, Volume: 139, Issue:1

    Topics: Anethole Trithione; Animals; Bile; Binding Sites; Butadienes; Cholagogues and Choleretics; Cysteine; Cytosol; Female; Fungicides, Industrial; gamma-Glutamyltransferase; Glutathione; Glycosuria; Kidney Cortex; Liver; Lyases; p-Aminohippuric Acid; Proteinuria; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds

1996
Bone marrow and renal injury associated with haloalkene cysteine conjugates in calves.
    Archives of toxicology, 1996, Volume: 70, Issue:10

    Topics: Animals; Bone Marrow; Butadienes; Cattle; Cysteine; Female; Fungicides, Industrial; Hydrocarbons, Halogenated; Kidney; Male

1996
Biotransformation, excretion, and nephrotoxicity of the hexachlorobutadiene metabolite (E)-N-acetyl-S-(1,2,3,4, 4-pentachlorobutadienyl)-L-cysteine sulfoxide.
    Chemical research in toxicology, 1998, Volume: 11, Issue:7

    Topics: Animals; Biotransformation; Butadienes; Chromatography, High Pressure Liquid; Cysteine; Female; Fungicides, Industrial; gamma-Glutamyltransferase; Glycosuria; Kidney Diseases; Male; Proteinuria; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Sulfoxides

1998