Page last updated: 2024-08-21

hesperidin and s 5682

hesperidin has been researched along with s 5682 in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's32 (60.38)18.2507
2000's13 (24.53)29.6817
2010's8 (15.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Foo, CL; Goh, HS; Ho, YH; Seow-Choen, F1
Nicolaides, AN; Struckmann, JR1
Launois, R1
Labrid, C1
Amato, C1
Guillot, B1
Geroulakos, G; Nicolaides, AN1
Bodinier, MC; Jean, T1
Cospite, M1
Godeberge, P1
Meyer, OC1
Galley, P; Thiollet, M1
Carrié, ML; Cypriani, B; Damon, M; de Paulet, AC; Le Doucen, C; Limasset, B; Roussie, M1
Friesenecker, B; Intaglietta, M; Tsai, AG1
Bouskela, E; Donyo, KA; Verbeuren, TJ1
Calinon, F; Delbarre, B; Delbarre, G1
Bollinger, A; Fischer, M; Franzeck, UK; Herrig, I; Hoffmann, U1
Belcaro, G; Cesarone, MR; De Gregoris, P; de Sanctis, MT; Février, B; Incandela, L; Laurora, G; Wargon, C1
Allegra, C; Bartolo, M; Carioti, B; Cassiani, D1
Bouskela, E; Cyrino, FZ; Lerond, L3
Geroulakos, G; Ibegbuna, V; Leon, M; Nicolaides, AN; Sowade, O1
Debure, C; Dereure, O; Dubeaux, D; Février, B; Gillet-Terver, MN; Guilhou, JJ; Guillot, B; Levesque, H; Marzin, L; Mignot, J; Ouvry, P; Pillion, G; Van Landuyt, H; Zuccarelli, F1
Février, B; Pecking, AP; Pillion, G; Wargon, C1
Bogachev, VIu; Domoradskaia, AI; Iablokov, EG1
Bouskela, E; Donyo, KA1
Andre, J; Guillot, R; Hadjiisky, P; Kassab, JP; Mozère, G; Ogneva, V; Peyroux, J; Sternberg, M1
Bellangeon, M; Chignier, E; Lerond, L; McGregor, JL; McGregor, L; Rousselle, C1
La Torre, F; Nicolai, AP; Otti, M1
Borisov, AV; Borisova, RP; Bubnova, NA1
Sirotin, BZ; Zhmerenetskĭ, KV1
Kharkevich, DA1
Kosorok, P; Mlakar, B1
Jedlicka, V; Kalac, J; Veverková, L; Wechsler, J1
Kirienko, AI; Oganov, RG; Savel'ev, VS; Shal'nova, SA; Zolotukhin, IA1
Baeshko, AA; Egorova, VV; Goretskaia, IV; Orlovskiĭ, IuN; Savitskaia, TV; Somova, OA; Ulezko, EA; Zhuk, GV1
Bogachev, VY; Burleva, EP; Katelnitsky, II; Kirienko, AI; Pokrovsky, AV; Sabelnikov, VV; Sapelkin, SV; Saveljev, VS; Shvalb, PG; Tolstikhin, VY; Voskanian, YE; Vozlubleny, SI; Zhukov, BN; Zolotukhin, IA1
Bakradze, M; Koridze, Kh; Ladashvili, L; Taboridze, I1
Aliev, ES; Aliev, SA; Ibishov, KG1
Rovenská, E; Rovenský, J; Stancíková, M; Stvrtinová, V; Svík, K1
Rovenská, E; Rovenský, J; Stancíková, M; Stvrtina, S; Stvrtinová, V; Svík, K1
Sapelkin, SV1
Bogachev, VIu; Golovanova, OV; Kuzhetsov, AN; Shekoian, AO1
Demidova, aK; Krivosheeva, NV; Rychkova, IV; Zubarev, AR1
Frolov, DV; Linchenko, DV; Poliantsev, AA; Shchelokova, IuV1
Anderson, LG; Azzam, EI; Bai, B; Ballent, M; Barrett, T; Beecher, C; Ben Amara, I; Ben Saad, H; Boerwinkle, E; Bonelli, F; Bouchet, P; Boudawara, O; Boudawara, T; Bressler, J; Brundha, C; Bukhari, S; Burger, R; Chang, LC; Chen, X; Cheng, Y; Coyne, DW; Crosbie, E; Cuaderes, E; de Toledo, SM; DeLuca, HF; DeShea, L; Devarakonda, K; Dias, LC; Dickerson, AS; Driss, D; Duda, TF; Dunn, AM; Dusso, A; Edoff, M; Ellouz Chaabouni, S; Fjällström, V; Flandre, D; Fujisawa, Y; Garland, RM; Giulivi, C; Groß, MA; Grove, ML; Hakim, A; Hamilton, ER; Han, L; Henry, F; Herlein, A; Hersey, SP; Hessabi, M; Huang, TQ; Iacono, WG; Jain, S; Jia, Y; Karuppuchamy, S; Kerzeli, IK; Keyes, M; Kim, MH; Klinger, S; Kostenbader, K; Kotipalli, R; Kotsianidis, I; Kózka, M; Kucharzewski, M; Lamb, WL; Lamprianidou, E; Leadlay, PF; Lee, MS; Lee, YS; Li, H; Li, T; Lifschitz, AL; Loveland, KA; Ma, J; Maté, LM; Matsui, T; McGue, MK; McLaughlin, W; Meier, RR; Meissner, G; Mereiter, K; Meyer, C; Miltiades, P; Montgomery, J; Morton, TL; Mounir Zeghal, K; Murphy, AC; Muscher-Banse, AS; Nagasaki, K; Nakou, E; Napoli, E; Nicolas, F; Ogata, T; Olivera, BM; Olson, GT; Papamichos, SI; Pasek, DA; Pietrzycka, A; Piketh, S; Podgorski, AL; Prediger, P; Puillandre, N; Rahbar, MH; Rosewarne, PJ; Rostvall, F; Samek, DR; Samms-Vaughan, M; Schnepel, N; Shakespeare-Pellington, S; Shibata, M; Shingler, T; Smucny, J; Song, G; Song, Q; Sorooshian, A; Spanoudakis, E; Stebbing, PD; Stevens, KE; Stpniewski, M; Takasu, A; Tregellas, JR; Urbanek, T; Valcour, A; Vermang, B; Vijayan, A; Virkel, G; Wall, JV; Wang, C; Wang, J; Wang, N; Wang, W; Wang, Y; Wätjen, JT; Webster, L; Weissensteiner, W; Wilkens, MR; Wong, S; Wu, C; Wu, Q; Yamada, T; Yamaguchi, R; Yue, J; Zhou, Y; Zierold, C; Zirakzadeh, A; Zou, MX1
Korzhyk, NP1
Nikolaichuk, AI; Tsukanov, YT1
Bogachev, VY; Boldin, BV; Turkin, PY1
Bogomazov, AM; Golovko, EB; Zagriadskiĭ, EA1

Reviews

6 review(s) available for hesperidin and s 5682

ArticleYear
Flavonoids. A review of the pharmacology and therapeutic efficacy of Daflon 500 mg in patients with chronic venous insufficiency and related disorders.
    Angiology, 1994, Volume: 45, Issue:6

    Topics: Animals; Chronic Disease; Diosmin; Drug Combinations; Flavonoids; Hesperidin; Humans; Venous Insufficiency

1994
Cellular basis of inflammation, edema and the activity of Daflon 500 mg.
    International journal of microcirculation, clinical and experimental, 1995, Volume: 15 Suppl 1

    Topics: Animals; Diosmin; Drug Combinations; Edema; Flavonoids; Hesperidin; Inflammation; Leukocytes; Microcirculation; Reperfusion Injury; Skin

1995
Intravital capillaroscopy in patients with chronic venous insufficiency and lymphoedema: relevance to Daflon 500 mg.
    International journal of microcirculation, clinical and experimental, 1995, Volume: 15 Suppl 1

    Topics: Diosmin; Drug Combinations; Flavonoids; Hesperidin; Humans; Lymphatic System; Lymphedema; Microcirculation; Microscopy, Fluorescence; Microscopy, Video; Skin; Venous Insufficiency

1995
[Hemorrhoids and conservative treatment. Review of the literature on the use of diosmin and micronized hesperidin].
    Minerva chirurgica, 1999, Volume: 54, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Diosmin; Double-Blind Method; Drug Combinations; Female; Flavonoids; Hemorrhoids; Hesperidin; Humans; Lymphedema; Male; Middle Aged; Placebos; Platelet Aggregation Inhibitors; Pregnancy; Thrombophlebitis; Time Factors

1999
[The principles of action and use of phlebotropic agents].
    Klinicheskaia meditsina, 2004, Volume: 82, Issue:11

    Topics: Diosmin; Drug Combinations; Flavonoids; Hesperidin; Humans; Sclerotherapy; Varicose Veins; Vasodilator Agents; Venous Insufficiency; Venous Thrombosis

2004
[Edema as a measure for severity of chronic venous insufficiency and efficacy of its treatment].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2008, Volume: 14, Issue:3

    Topics: Chronic Disease; Diosmin; Drug Combinations; Edema; Hesperidin; Humans; Prognosis; Severity of Illness Index; Venous Insufficiency

2008

Trials

19 trial(s) available for hesperidin and s 5682

ArticleYear
Prospective randomized controlled trial of a micronized flavonidic fraction to reduce bleeding after haemorrhoidectomy.
    The British journal of surgery, 1995, Volume: 82, Issue:8

    Topics: Adult; Diosmin; Drug Combinations; Female; Flavonoids; Hemorrhage; Hemorrhoids; Hesperidin; Humans; Male; Postoperative Complications; Prospective Studies

1995
Advantage of a micronized flavonoidic fraction (Daflon 500 mg) in comparison with a nonmicronized diosmin.
    Angiology, 1994, Volume: 45, Issue:6 Pt 2

    Topics: Adult; Chronic Disease; Diosmin; Dosage Forms; Double-Blind Method; Drug Combinations; Female; Flavonoids; Hesperidin; Humans; Male; Middle Aged; Patient Satisfaction; Plethysmography; Venous Insufficiency

1994
Controlled studies of Daflon 500 mg in chronic venous insufficiency.
    Angiology, 1994, Volume: 45, Issue:6 Pt 2

    Topics: Diosmin; Drug Combinations; Flavonoids; Hesperidin; Humans; Plethysmography; Randomized Controlled Trials as Topic; Venous Insufficiency

1994
Double-blind, placebo-controlled evaluation of clinical activity and safety of Daflon 500 mg in the treatment of acute hemorrhoids.
    Angiology, 1994, Volume: 45, Issue:6 Pt 2

    Topics: Acute Disease; Adult; Aged; Diosmin; Double-Blind Method; Drug Combinations; Female; Flavonoids; Hemorrhoids; Hesperidin; Humans; Male; Middle Aged

1994
Daflon 500 mg in the treatment of hemorrhoidal disease: a demonstrated efficacy in comparison with placebo.
    Angiology, 1994, Volume: 45, Issue:6 Pt 2

    Topics: Acute Disease; Chronic Disease; Diosmin; Double-Blind Method; Drug Combinations; Female; Flavonoids; Hemorrhoids; Hesperidin; Humans; Male; Middle Aged

1994
A double-blind, placebo-controlled trial of a new veno-active flavonoid fraction (S 5682) in the treatment of symptomatic capillary fragility.
    International angiology : a journal of the International Union of Angiology, 1993, Volume: 12, Issue:1

    Topics: Aged; Capillary Fragility; Capillary Resistance; Diosmin; Double-Blind Method; Drug Combinations; Female; Flavonoids; Hemorrhage; Hesperidin; Humans; Male

1993
Laser Doppler and transcutaneous oximetry: modern investigations to assess drug efficacy in chronic venous insufficiency.
    International journal of microcirculation, clinical and experimental, 1995, Volume: 15 Suppl 1

    Topics: Adult; Blood Gas Monitoring, Transcutaneous; Diosmin; Double-Blind Method; Drug Combinations; Female; Flavonoids; Hesperidin; Humans; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Skin; Venous Insufficiency

1995
An original microhaemorheological approach to the pharmacological effects of Daflon 500 mg in severe chronic venous insufficiency.
    International journal of microcirculation, clinical and experimental, 1995, Volume: 15 Suppl 1

    Topics: Adult; Aged; Diosmin; Drug Combinations; Female; Flavonoids; Hesperidin; Humans; Male; Microcirculation; Microscopy, Fluorescence; Microscopy, Video; Middle Aged; Rheology; Skin; Venous Insufficiency

1995
Venous elasticity after treatment with Daflon 500 mg.
    Angiology, 1997, Volume: 48, Issue:1

    Topics: Adolescent; Adult; Diosmin; Drug Combinations; Elasticity; Female; Flavonoids; Hesperidin; Humans; Varicose Veins; Veins

1997
Efficacy of Daflon 500 mg in venous leg ulcer healing: a double-blind, randomized, controlled versus placebo trial in 107 patients.
    Angiology, 1997, Volume: 48, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Diosmin; Double-Blind Method; Drug Combinations; Female; Flavonoids; Hesperidin; Humans; Leg Ulcer; Male; Middle Aged; Pressure; Treatment Outcome

1997
Efficacy of Daflon 500 mg in the treatment of lymphedema (secondary to conventional therapy of breast cancer).
    Angiology, 1997, Volume: 48, Issue:1

    Topics: Aged; Breast Neoplasms; Diosmin; Double-Blind Method; Drug Combinations; Female; Flavonoids; Hesperidin; Humans; Lymphedema; Middle Aged

1997
[The drug therapy of chronic venous insufficiency (a trial of the clinical use of the preparation Detralex)].
    Terapevticheskii arkhiv, 1996, Volume: 68, Issue:10

    Topics: Chronic Disease; Diosmin; Drug Combinations; Flavonoids; Hesperidin; Humans; Tablets; Time Factors; Venous Insufficiency

1996
[Microcirculation end effect of detralex in patients with chronic venous insufficiency of the lower extremities].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2003, Volume: 9, Issue:3

    Topics: Chronic Disease; Diosmin; Drug Combinations; Erythrocyte Aggregation; Female; Hesperidin; Humans; Male; Microcirculation; Middle Aged; Severity of Illness Index; Varicose Veins

2003
Flavonoids to reduce bleeding and pain after stapled hemorrhoidopexy: a randomized controlled trial.
    Wiener klinische Wochenschrift, 2005, Volume: 117, Issue:15-16

    Topics: Analgesics; Anti-Inflammatory Agents; Diosmin; Drug Combinations; Female; Flavonoids; Hemorrhoids; Hesperidin; Humans; Intestinal Mucosa; Male; Melena; Middle Aged; Pain, Postoperative; Pelvic Pain; Surgical Stapling; Treatment Outcome

2005
[Analysis of surgical procedures on the vena saphena magna in the Czech Republic and an effect of Detralex during its stripping].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 2005, Volume: 84, Issue:8

    Topics: Adolescent; Adult; Chronic Disease; Diosmin; Drug Combinations; Hesperidin; Humans; Middle Aged; Pain Measurement; Pain, Postoperative; Postoperative Complications; Quality of Life; Saphenous Vein; Vascular Surgical Procedures; Venous Insufficiency

2005
[Congenital anomalies of the inferior vena cava: diagnosis and medical treatment].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2007, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Diagnosis, Differential; Diosmin; Drug Combinations; Fibrinolytic Agents; Heparin; Hesperidin; Humans; Male; Ultrasonography, Doppler; Vascular Surgical Procedures; Vena Cava, Inferior; Venous Insufficiency

2007
Surgical correction of varicose vein disease under micronized diosmin protection (results of the Russian multicenter controlled trial DEFANS).
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2007, Volume: 13, Issue:2

    Topics: Adult; Aged; Arteries; Combined Modality Therapy; Diosmin; Drug Combinations; Female; Hesperidin; Humans; Middle Aged; Varicose Veins; Vascular Surgical Procedures; Veins

2007
[On advisability of perioperative phleboprotection in endovascular treatment of lower in varicose disease: first initial results of the decision study].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2012, Volume: 18, Issue:2

    Topics: Administration, Oral; Adult; Compression Bandages; Diosmin; Drug Combinations; Endovascular Procedures; Female; Flavonoids; Hesperidin; Humans; Lower Extremity; Male; Middle Aged; Perioperative Care; Protective Agents; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome; Varicose Veins; Veins

2012
    Organometallics, 2015, Aug-10, Volume: 34, Issue:15

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Advanced Oxidation Protein Products; Aged; Aged, 80 and over; Analgesics, Opioid; Animals; Antibodies, Monoclonal; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Automation; Benzaldehydes; Bromates; Calcifediol; Calcitriol; Carcinoma, Squamous Cell; Catalase; Chromatography, Liquid; Coloring Agents; Cross-Over Studies; Cross-Sectional Studies; Cytochrome P-450 CYP3A; Cytokines; Diabetic Foot; Diabetic Neuropathies; Diagnostic Self Evaluation; Diosmin; DNA Damage; Double-Blind Method; Drug Combinations; Electrodes; Endothelin-1; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Exercise; Female; Follow-Up Studies; Gene Expression Regulation; Glutathione; Hesperidin; Humans; Illicit Drugs; Indians, North American; Injections, Intravenous; Interferometry; Interleukin-1beta; Interleukin-6; Interviews as Topic; Ions; Jejunum; Kidney; Leukocyte Count; Lipid Peroxidation; Lithium; Liver; Luminescent Measurements; Male; Mice; Middle Aged; Monocytes; Nanostructures; Oklahoma; Organ Specificity; Oxidative Stress; Oxycodone; Photochemistry; Predictive Value of Tests; Pregnane X Receptor; Preoperative Period; Prescription Drugs; Receptors, Steroid; Reference Values; Reproducibility of Results; Retinoid X Receptor alpha; Retrospective Studies; RNA, Messenger; Rumen; Sheep, Domestic; Shoes; Solar Energy; Superoxide Dismutase; Survival Rate; Tandem Mass Spectrometry; Titanium; Treatment Outcome; Tumor Necrosis Factor-alpha; Varicose Veins; Vitamin D; Water Pollutants, Chemical; Weight-Bearing; Young Adult

2015

Other Studies

28 other study(ies) available for hesperidin and s 5682

ArticleYear
At the Crossroads of Venous Insufficiency and Hemorrhoidal Disease: Daflon 500 mg. Proceedings of a symposium. Vienna, Austria, January 31, 1992.
    Angiology, 1994, Volume: 45, Issue:6 Pt 2

    Topics: Diosmin; Drug Combinations; Flavonoids; Hemorrhoids; Hesperidin; Humans; Venous Insufficiency

1994
At the crossroads of venous insufficiency and hemorrhoidal disease: Daflon 500 mg--repercussions of venous insufficiency on everyday life.
    Angiology, 1994, Volume: 45, Issue:6 Pt 2

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Aged, 80 and over; Diosmin; Drug Combinations; Female; Flavonoids; Hesperidin; Humans; Male; Middle Aged; Pain; Quality of Life; Varicose Veins; Venous Insufficiency

1994
Pharmacologic properties of Daflon 500 mg.
    Angiology, 1994, Volume: 45, Issue:6 Pt 2

    Topics: Animals; Capillary Permeability; Diabetes Mellitus, Experimental; Dinoprostone; Diosmin; Dogs; Drug Combinations; Edema; Flavonoids; Hesperidin; Inflammation; Kidney Glomerulus; Lymph; Muscles; Rats; Thoracic Duct; Thromboxane B2

1994
Techniques used to evaluate the cutaneous microcirculation: application of photoplethysmography to the assessment of a phlebotropic agent in the treatment of leg ulcers.
    Angiology, 1994, Volume: 45, Issue:6 Pt 2

    Topics: Blood Pressure; Diosmin; Drug Combinations; Flavonoids; Hesperidin; Humans; Leg Ulcer; Microcirculation; Photoplethysmography; Skin; Varicose Ulcer; Venous Insufficiency

1994
Mediators involved in inflammation: effects of Daflon 500 mg on their release.
    Angiology, 1994, Volume: 45, Issue:6 Pt 2

    Topics: Alloxan; Animals; Anti-Inflammatory Agents; Blood Glucose; Diabetes Mellitus, Experimental; Diosmin; Drug Combinations; Flavonoids; Free Radicals; Granuloma; Hesperidin; Humans; Inflammation; Kidney Glomerulus; Macrophages; Mice; Neutrophils; Permeability; Prostaglandins; Rats; Thromboxane B2

1994
Safety and security of Daflon 500 mg in venous insufficiency and in hemorrhoidal disease.
    Angiology, 1994, Volume: 45, Issue:6 Pt 2

    Topics: Animals; Clinical Trials as Topic; Diosmin; Drug Combinations; Flavonoids; Hemorrhoids; Hesperidin; Humans; Mice; Rats; Rats, Wistar; Venous Insufficiency

1994
Antioxidant activity of micronized diosmin on oxygen species from stimulated human neutrophils.
    Biochemical pharmacology, 1993, Apr-06, Volume: 45, Issue:7

    Topics: Acridines; Antioxidants; Diosmin; Drug Combinations; Free Radicals; Hesperidin; Humans; Luminescent Measurements; Luminol; Neutrophils; Peroxidase; Reactive Oxygen Species; Tetradecanoylphorbol Acetate

1993
Effects of Daflon 500 mg on increased microvascular permeability in normal hamsters.
    International journal of microcirculation, clinical and experimental, 1995, Volume: 15 Suppl 1

    Topics: Animals; Bradykinin; Capillary Permeability; Cheek; Cricetinae; Diosmin; Drug Combinations; Flavonoids; Hesperidin; Histamine; Leukotriene B4; Male

1995
Effect of Daflon 500 mg, a flavonoid drug, on neurological signs, levels of free radicals and electroretinogram in the gerbil after ischemia-reperfusion injury.
    International journal of microcirculation, clinical and experimental, 1995, Volume: 15 Suppl 1

    Topics: Animals; Behavior, Animal; Brain Ischemia; Diosmin; Drug Combinations; Electroretinography; Female; Flavonoids; Free Radicals; Gerbillinae; Hesperidin; Lipid Peroxidation; Male; Reperfusion Injury; Retina

1995
Microvascular reactivity after ischemia/reperfusion in the hamster cheek pouch: beneficial effects of different oral doses of S-5682 (Daflon 500 mg).
    Angiology, 1997, Volume: 48, Issue:1

    Topics: Animals; Arterioles; Cheek; Cricetinae; Diosmin; Dose-Response Relationship, Drug; Drug Combinations; Flavonoids; Hesperidin; Ischemia; Male; Mesocricetus; Microcirculation; Regional Blood Flow; Reperfusion; Vasomotor System; Venules

1997
Proceedings of the XII World Congress of the International Union of Phlebology--parallel session entitled medical and socioeconomic impact of venolymphatic disease: benefit of daflon 500 mg. London, 1995.
    Angiology, 1997, Volume: 48, Issue:1

    Topics: Animals; Diosmin; Drug Combinations; Hesperidin; Humans; Vascular Diseases

1997
Effects of oral administration of purified micronized flavonoid fraction on increased microvascular permeability induced by various agents and on ischemia/reperfusion in the hamster cheek pouch.
    Angiology, 1997, Volume: 48, Issue:5

    Topics: Administration, Oral; Animals; Capillary Permeability; Cell Adhesion; Cheek; Cricetinae; Diosmin; Drug Combinations; Flavonoids; Hesperidin; Leukocytes; Male; Reperfusion Injury

1997
Effects of oral administration of different doses of purified micronized flavonoid fraction on microvascular reactivity after ischaemia/reperfusion in the hamster cheek pouch.
    British journal of pharmacology, 1997, Volume: 122, Issue:8

    Topics: Administration, Oral; Animals; Arterioles; Cheek; Cricetinae; Diosmin; Drug Combinations; Hesperidin; Ischemia; Male; Regional Blood Flow; Reperfusion; Venules

1997
Effect of long-term treatment with a purified micronized flavonoid fraction on pancreatic mononuclear cell infiltration in diabetic BB rats.
    Pancreas, 1998, Volume: 17, Issue:3

    Topics: Animals; C-Peptide; Chemotaxis, Leukocyte; Diabetes Mellitus, Type 1; Diosmin; Drug Combinations; Fibrinogen; Flavonoids; Fructosamine; Hesperidin; Islets of Langerhans; Leukocytes, Mononuclear; Male; Orosomucoid; Rats; Rats, Inbred BB

1998
Effect of a micronized purified flavonoid fraction on in vivo platelet functions in the rat.
    Thrombosis research, 1999, May-15, Volume: 94, Issue:4

    Topics: Animals; Collagen; Diosmin; Drug Combinations; Flavonoids; Hesperidin; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar

1999
Leukocyte adhesion after oxidant challenge in the hamster cheek pouch microcirculation.
    Journal of vascular research, 1999, Volume: 36 Suppl 1

    Topics: Animals; Antioxidants; Cell Adhesion; Cheek; Cricetinae; Diosmin; Drug Combinations; Hesperidin; Leukocytes; Male; Mesocricetus; Microcirculation; Oxidants; tert-Butylhydroperoxide; Vitamin E

1999
[The theory of lymphangion and current approaches to the pathogenesis, diagnosis and treatment of lymphedema of the lower extremities].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2003, Volume: 9, Issue:2

    Topics: Animals; Biopsy; Diosmin; Drug Combinations; Electric Stimulation Therapy; Hesperidin; Humans; Leg; Lymphatic System; Lymphatic Vessels; Lymphedema; Lymphography

2003
[Risk factors of chronic venous insufficiency of the lower extremities and possibilities of its medication in therapeutic practice].
    Terapevticheskii arkhiv, 2006, Volume: 78, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Bandages; Chronic Disease; Constipation; Diosmin; Drug Combinations; Exercise Therapy; Female; Hesperidin; Humans; Incidence; Leg; Male; Middle Aged; Obesity; Risk Factors; Sex Factors; Treatment Outcome; Venous Insufficiency

2006
[Immunological aspects of aphthous stomatitis].
    Georgian medical news, 2007, Issue:151

    Topics: Adolescent; Adult; Antigens, CD; Diosmin; Drug Combinations; Female; Hesperidin; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Interleukin-6; Male; Middle Aged; Stomatitis, Aphthous

2007
[Certain aspects of pathogenesis of hemorheological and trophic disturbances and their pharmacological correction in patients with chronic venous insufficiency].
    Vestnik khirurgii imeni I. I. Grekova, 2008, Volume: 167, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity; Blood Viscosity; Chronic Disease; Diosmin; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Foot Ulcer; Glycosides; Hesperidin; Humans; Leg; Male; Middle Aged; Phlebography; Recurrence; Severity of Illness Index; Thrombophlebitis; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Duplex; Venous Insufficiency

2008
Effects of purified micronized flavonoid fraction (Detralex) on prophylactic treatment of adjuvant arthritis with methotrexate in rats.
    The Israel Medical Association journal : IMAJ, 2008, Volume: 10, Issue:5

    Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Bone Density; Diosmin; Drug Combinations; Edema; Hesperidin; Male; Methotrexate; Nitrates; Nitrites; Plethysmography; Rats; Serum Albumin; Severity of Illness Index

2008
Treatment of rat adjuvant arthritis with flavonoid (Detralex), methotrexate, and their combination.
    Annals of the New York Academy of Sciences, 2009, Volume: 1173

    Topics: Animals; Arthritis, Experimental; Diosmin; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Hesperidin; Hindlimb; Immunosuppressive Agents; Male; Methotrexate; Nitrates; Nitrites; Rats; Rats, Inbred Lew; Serum Albumin; Treatment Outcome

2009
[Ultrasound elastography in assessing efficacy of treatment for lower limb varicose veins with a phlebotrophic drug containing a micronized purified flavonoid fraction].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2014, Volume: 20, Issue:2

    Topics: Biological Availability; Diosmin; Drug Combinations; Drug Monitoring; Elasticity; Elasticity Imaging Techniques; Feasibility Studies; Female; Flavonoids; Hesperidin; Humans; Lower Extremity; Male; Middle Aged; Phlebitis; Saphenous Vein; Severity of Illness Index; Treatment Outcome; Varicose Veins; Venous Insufficiency

2014
[Application of rivaroxabane in patients with proteins C and S deficiency].
    Khirurgiia, 2014, Issue:9

    Topics: Adult; Anticoagulants; Blood Coagulation; Diosmin; Drug Combinations; Drug Monitoring; Female; Hesperidin; Humans; Male; Morpholines; Protein C Deficiency; Protein S Deficiency; Rivaroxaban; Thiophenes; Time; Treatment Outcome; Venous Thrombosis

2014
[VARICOSE DISEASE OF THE LOWER EXTREMITIES: CAUSES, COMPLICATIONS, CHOICE OF METHODS FOR TREATMENT AND PROPHYLAXIS].
    Klinichna khirurhiia, 2016, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angioplasty; Antioxidants; Diosmin; Disease Management; Drug Combinations; Female; Heme; Hesperidin; Humans; Lower Extremity; Male; Middle Aged; Retrospective Studies; Saphenous Vein; Sclerotherapy; Severity of Illness Index; Silicones; Sorption Detoxification; Treatment Outcome; Varicose Veins; Venous Insufficiency

2016
[Transitory (evening) venous reflux in patients with intracutaneous varicosity and medicamentous correction thereof].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2016, Volume: 22, Issue:2

    Topics: Adult; Cardiovascular Agents; Diosmin; Drug Combinations; Female; Flavonoids; Hesperidin; Humans; Lower Extremity; Quality of Life; Russia; Severity of Illness Index; Telangiectasis; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Duplex; Varicose Veins

2016
Administration of Micronized Purified Flavonoid Fraction During Sclerotherapy of Reticular Veins and Telangiectasias: Results of the National, Multicenter, Observational Program VEIN ACT PROLONGED-C1.
    Advances in therapy, 2018, Volume: 35, Issue:7

    Topics: Administration, Oral; Adult; Chronic Disease; Diosmin; Drug Combinations; Edema; Female; Flavonoids; Hesperidin; Humans; Male; Middle Aged; Pain; Pre-Exposure Prophylaxis; Quality of Life; Sclerotherapy; Surveys and Questionnaires; Telangiectasis; Treatment Outcome

2018
Conservative Treatment of Hemorrhoids: Results of an Observational Multicenter Study.
    Advances in therapy, 2018, Volume: 35, Issue:11

    Topics: Adult; Chronic Disease; Conservative Treatment; Diosmin; Drug Combinations; Female; Flavonoids; Hemorrhage; Hemorrhoids; Hesperidin; Humans; Male; Middle Aged; Russia; Secondary Prevention; Severity of Illness Index; Symptom Assessment; Treatment Outcome

2018