hesperidin has been researched along with neohesperidin in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (3.13) | 29.6817 |
| 2010's | 33 (51.56) | 24.3611 |
| 2020's | 29 (45.31) | 2.80 |
| Authors | Studies |
|---|---|
| Jeong, CS; Kim, YS; Lee, JH; Lee, SH | 1 |
| Chen, JC; He, YC; Li, LJ; Liu, HX; Wen, SM; Zheng, QS | 1 |
| Caccamese, S; Chillemi, R | 1 |
| Chen, K; Huang, J; Li, X; Luo, F; Sun, C; Zhang, J; Zhu, X | 1 |
| Duan, JA; Lu, LL; Qian, DW; Qian, YF; Shu, Y; Su, SL; Xue, CF | 1 |
| Jenwitheesuk, E; Puchadapirom, P; Suthiyotha, N; Toniti, W | 1 |
| Chen, K; Chen, Q; Li, X; Luo, F; Sun, C; Yan, Y; Zhang, J; Zhu, X | 1 |
| Balasubramaniam, VM; Jayaprakasha, GK; Patil, BS; Uckoo, RM | 1 |
| Lu, YH; Shen, W; Xu, Y | 1 |
| Chen, D; Lu, M; Xu, F; Zang, J; Zhan, H; Zhang, T; Zhuge, H | 1 |
| Chen, J; Jiang, P; Qiao, L; Shen, Y; Sun, Y; Ye, X | 1 |
| Cui, P; Wang, JJ | 1 |
| Nam, HK; Oh, DK; Shin, KC | 1 |
| El-Shazly, AM; Hamdan, DI; Mahmoud, MF; Wink, M | 1 |
| Ge, SB; Hou, ZS; Pan, JH; Yan, GJ | 1 |
| Du, G; Gao, Z; Gong, N; Lu, Y; Yang, D; Zhang, B | 1 |
| Chen, K; Chen, Y; Hu, Y; Jia, S; Li, X; Sun, C; Zhang, W; Zhao, X | 1 |
| Chang, YS; Chen, P; Zhao, Y | 1 |
| Bian, Z; Ho, SL; Kwong, DW; Li, HW; Lin, C; Poon, CY; Wong, MS; Yan, T; Yung, KK | 1 |
| Banjerdpongchai, R; Duangnil, N; Khaw-On, P; Kongtawelert, P; Rachakhom, W; Wudtiwai, B | 1 |
| Goscinny, S; Janvier, S; Le Donne, C; Van Loco, J | 1 |
| Cao, J; Cao, W; Hu, SS; Peng, LQ; Xu, JJ; Yang, R; Ye, LH | 1 |
| Dai, TY; Jiang, JP; Lin, SY; Qian, WB; Wang, B; Wu, LQ | 1 |
| Jia, H; Li, X; Wu, S; Xi, M; Xu, L; Zhu, Y | 1 |
| Cheng, J; Hong, G; Kenny, J; Lin, X; Liu, Q; Qin, A; Quinn, JMW; Tan, Z; Tickner, J; Wang, T; Xu, J; Yuan, J; Zhao, J; Zhou, L | 1 |
| Chen, K; Chen, X; He, Q; Li, X; Liu, Y; Ma, J; Si, M; Sun, C; Wu, H; Yan, Y; Yang, B; Zhu, D | 1 |
| Gao, W; Li, P; Liu, X; Luo, F; She, Y | 1 |
| Bai, Y; Cheng, J; Deng, W; Li, P; Pang, W; Peng, W; Su, W; Wu, H; Yao, H; Zheng, Y | 1 |
| Liu, X; Wang, J; Yuan, Y; Zhang, H; Zhang, P; Zhang, Y | 1 |
| Chen, D; Guo, S; Liu, Y; Yu, H; Zhang, H | 1 |
| An, H; Che, D; Ding, Y; Fu, J; Gao, Z; Hu, S; Li, C; Liu, R; Ma, P; Wang, J; Zhang, T; Zhang, Y; Zhao, T | 1 |
| Cao, J; Cui, S; Dong, R; Gao, X; Gong, Y; He, Q; Jiang, L; Li, J; Yang, B; Ying, M; Zheng, J | 1 |
| Fang, Y; Guo, J; Jiang, F; Li, L; Ning, W; Xu, X; Zhou, H | 1 |
| Guan, X; Guo, C; Zhang, H; Zhou, Z | 1 |
| Feng, F; Zhang, Q | 1 |
| Abdul, Q; Chen, W; Hou, J; Jiang, Z; Li, T; Ma, L; Tian, B; Yu, H | 1 |
| Ding, Y; Fu, X; Liu, F; Lou, Y; Wen, H; Yang, L; Yang, Q; Zhang, J; Zhang, L | 1 |
| Chai, X; Wang, D; Wang, Y; Yang, J; Zhang, J; Zhang, X | 1 |
| Liu, H; Lu, JF; Peng, L; Shi, X; Wang, YL; Wu, JW; Xia, B; Zhang, H; Zhu, MQ | 1 |
| Li, S; Liu, C; Shi, D; Tsao, R; Zhang, Y | 1 |
| Bai, YF; Fan, XY; Lou, LJ; Sheng, H; Wang, SW; Weng, YY; Zhang, F | 1 |
| Liu, Q; Wan, W; Xia, N; Zhu, S | 1 |
| Chen, W; Karim, N; Shishir, MRI | 1 |
| Antony, PJ; Gan, RY; Gandhi, GR; Geng, F; Gurgel, RQ; Li, H; Li, HB; Narain, N; Vasconcelos, ABS; Wu, DT | 1 |
| Wang, B; Yuan, S; Zhang, C; Zhu, Y | 1 |
| Bandyopadhyay, J; Basu, S; Chakraborty, S; Rakshit, J | 1 |
| Li, A; Luo, Q; Zhang, X | 1 |
| Dai, MY; Li, F; Liu, HN; Ma, XF; Wang, YK; Xiao, XR; Zhang, SW; Zhou, ZM | 1 |
| Cui, SS; Li, M; Li, RM; Qiu, ZC; Tan, X; Yuan, YL; Zhang, FX | 1 |
| Chen, W; Karim, N; Ke, H; Rashwan, AK; Shishir, MRI | 1 |
| Chang, YW; Gu, W; Li, ZQ; Sun, J; Wei, XE; Zhu, WJ | 1 |
| Arai, R; Hakamatsuka, T; Ozeki, Y; Tsujimoto, T; Uchiyama, N; Yamamoto, Y; Yoshitomi, T | 1 |
| Abo-Youssef, AM; Hassan, MIA; Hemeida, RAM; Osman, AT; Sharkawi, SMZ | 2 |
| Ji, G; Li, Z; Liu, W; Wang, S; Wei, G; Yu, N | 1 |
| Chen, Y; Wang, B; Yuan, S; Zhang, C | 1 |
| Dai, C; Li, L; Liu, R; Wang, J; Wang, XH; Yin, ZS | 1 |
| Wang, B; Yuan, S; Zhang, C | 1 |
| Wang, C; Xia, N; Zhu, S | 1 |
| Bellini, MZ; Buchaim, DV; Buchaim, RL; de Marchi, MÂ; Detregiachi, CRP; Fideles, SOM; Flato, UAP; Gardizani, TP; Ortiz, AC; Pagani, BT; Pereira, ESBM; Pilon, JPG; Ponce, JB; Reis, CHB; Trazzi, BFM; Veronez, FS | 1 |
| Bernroider, M; Chen, L; Feng, GW; Genser, J; Hierlmeier, G; Hu, XX; Lan, YJ; Leitner, C; Li, H; Lin, DF; Lyu, KY; Meng, L; Neubauer, F; Qu, X; Shen, T; Sun, RC; Wang, C; Weng, SF; Wolf, R; Xu, QY; Yang, SX; Yao, ZM; Zhang, LZ; Zhang, M; Zhang, NX; Zhang, X; Zhu, DX; Zhu, JJ; Zhu, S | 1 |
| Bian, BL; Han, L; Li, ML; Si, N; Wang, HJ; Wu, HK; Yang, LX; Zhang, Y; Zhao, HY; Zhou, YY; Zhu, HY | 1 |
| Dubey, S; Siddiqi, MI; Singh, JK; Srivastava, G; Srivastava, SK | 1 |
| He, Z; Kong, X; Sun, C; Tian, J; Yang, W; Ye, X; Zuo, Y | 1 |
2 review(s) available for hesperidin and neohesperidin
| Article | Year |
|---|---|
Citrus Flavonoids as Promising Phytochemicals Targeting Diabetes and Related Complications: A Systematic Review of In Vitro and In Vivo Studies.
Topics: Animals; Antioxidants; Citrus; Diabetes Mellitus; Disaccharides; Flavanones; Flavones; Flavonoids; Glycosides; Hesperidin; Humans; Inflammation; Phytochemicals; Polyphenols; Propiophenones | 2020 |
Therapeutic Effects of Citrus Flavonoids Neohesperidin, Hesperidin and Its Aglycone, Hesperetin on Bone Health.
Topics: Bone Density; Citrus; Flavanones; Flavonoids; Hesperidin; Osteoporosis | 2022 |
62 other study(ies) available for hesperidin and neohesperidin
| Article | Year |
|---|---|
Protective effects of neohesperidin and poncirin isolated from the fruits of Poncirus trifoliata on potential gastric disease.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Cell Line, Tumor; Flavonoids; Fruit; Gastritis; Hesperidin; Humans; Male; Molecular Structure; Phytotherapy; Plant Extracts; Poncirus; Rats; Rats, Sprague-Dawley | 2009 |
[Anti-inflammatory effects and quantitative study of the combinations of active ingredients of Painong powder in mice].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bridged-Ring Compounds; Drug Evaluation, Preclinical; Drug Synergism; Drugs, Chinese Herbal; Female; Flavanones; Glucosides; Hesperidin; Male; Mice; Monoterpenes; Powders; Saponins | 2009 |
Racemization at C-2 of naringin in pummelo (Citrus grandis) with increasing maturity determined by chiral high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Citrus; Flavanones; Flavonoids; Fruit; Hesperidin; Plant Extracts; Stereoisomerism | 2010 |
Separation and purification of neohesperidin from the albedo of Citrus reticulata cv. Suavissima by combination of macroporous resin and high-speed counter-current chromatography.
Topics: Chromatography; Citrus; Countercurrent Distribution; Hesperidin; Molecular Structure; Plant Extracts; Resins, Synthetic | 2012 |
[Identification of the metabolites of Sinisan extract in rat plasma, urine, feces and bile after intragastric administration].
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Glucosides; Glycyrrhizic Acid; Hesperidin; Hydroxylation; Male; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2011 |
Binding capacity of ER-α ligands and SERMs: comparison of the human, dog and cat.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Breast Neoplasms; Cats; Chalcones; Dogs; Estrogen Receptor alpha; Female; Hesperidin; Humans; Indoles; Ligands; Mammary Glands, Animal; Mammary Glands, Human; Molecular Sequence Data; Protein Structure, Secondary; Selective Estrogen Receptor Modulators; Sequence Alignment; Sequence Analysis, Protein | 2011 |
Purification of naringin and neohesperidin from Huyou (Citrus changshanensis) fruit and their effects on glucose consumption in human HepG2 cells.
Topics: Citrus; Flavanones; Fruit; Glucose; Hep G2 Cells; Hesperidin; Humans; Plant Extracts | 2012 |
Grapefruit (Citrus paradisi Macfad) phytochemicals composition is modulated by household processing techniques.
Topics: Ascorbic Acid; Beverages; Chromatography, High Pressure Liquid; Citric Acid; Citrus paradisi; Disaccharides; Flavanones; Flavonoids; Food Handling; Furocoumarins; Glycosides; Hesperidin; Limonins; Plant Extracts | 2012 |
Inhibitory effects of Citrus flavonoids on starch digestion and antihyperglycemic effects in HepG2 cells.
Topics: Amylopectin; Amylose; Animals; Citrus; Digestion; Drug Evaluation, Preclinical; Flavanones; Flavones; Flavonoids; Glucokinase; Glucose; Glycogen; Hep G2 Cells; Hesperidin; Humans; Hypoglycemic Agents; Iodine; Liver; Pancreatic alpha-Amylases; Starch | 2012 |
Neohesperidin induces cellular apoptosis in human breast adenocarcinoma MDA-MB-231 cells via activating the Bcl-2/Bax-mediated signaling pathway.
Topics: Adenocarcinoma; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; Hesperidin; Humans; Phytotherapy; Plant Extracts; Signal Transduction | 2012 |
Phytochemical profile and antioxidant activity of physiological drop of citrus fruits.
Topics: Antioxidants; China; Citrus; Coumaric Acids; Dietary Supplements; Disaccharides; Flavanones; Flavones; Fruit; Hesperidin; Hydroxybenzoates; Limonins; Plant Extracts; Synephrine | 2013 |
Neohesperidin attenuates cerebral ischemia-reperfusion injury via inhibiting the apoptotic pathway and activating the Akt/Nrf2/HO-1 pathway.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Caspase 9; Heme Oxygenase-1; Hesperidin; Infarction, Middle Cerebral Artery; Male; Molecular Structure; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Up-Regulation | 2013 |
Hydrolysis of flavanone glycosides by β-glucosidase from Pyrococcus furiosus and its application to the production of flavanone aglycones from citrus extracts.
Topics: beta-Glucosidase; Citrus; Detergents; Disaccharides; Flavanones; Flavonoids; Food Industry; Glycosides; Hesperidin; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Plant Extracts; Pyrococcus furiosus; Solvents; Substrate Specificity; Temperature | 2013 |
Effect of hesperidin and neohesperidin from bittersweet orange (Citrus aurantium var. bigaradia) peel on indomethacin-induced peptic ulcers in rats.
Topics: Animals; Citrus; Cyclooxygenase 2; Fruit; Gastric Mucosa; Glutathione; Hesperidin; Indomethacin; Male; Malondialdehyde; Peptic Ulcer; Rats, Wistar; Stomach; Tumor Necrosis Factor-alpha | 2014 |
[Study on HPLC fingerprint of Ganershu intermediate and determination of three active components].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chlorogenic Acid; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Flavanones; Hesperidin; Plants, Medicinal; Quality Control; Reproducibility of Results | 2013 |
Development of new reference material neohesperidin for quality control of dietary supplements.
Topics: Antioxidants; Calibration; Calorimetry, Differential Scanning; China; Chromatography, High Pressure Liquid; Dietary Supplements; Food Inspection; Hesperidin; Molecular Weight; Quality Control; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Time Factors; Titrimetry; Uncertainty | 2015 |
Hypoglycemic and hypolipidemic effects of neohesperidin derived from Citrus aurantium L. in diabetic KK-A(y) mice.
Topics: Adipose Tissue, White; Adiposity; Animals; Blood Proteins; Citrus; Diabetes Mellitus, Type 2; Diet, Diabetic; Dietary Supplements; Gene Expression Regulation, Enzymologic; Glycated Serum Proteins; Glycoproteins; Hesperidin; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Resistance; Lipid Metabolism; Liver; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Random Allocation; Specific Pathogen-Free Organisms | 2015 |
Differentiation of Aurantii Fructus Immaturus from Poniciri Trifoliatae Fructus Immaturus using flow-injection mass spectrometric (FIMS) metabolic fingerprinting method combined with chemometrics.
Topics: Citrus; Drugs, Chinese Herbal; Flavanones; Flow Injection Analysis; Hesperidin; Mass Spectrometry; Principal Component Analysis | 2015 |
Inhibition of β-amyloid Aggregation By Albiflorin, Aloeemodin And Neohesperidin And Their Neuroprotective Effect On Primary Hippocampal Cells Against β-amyloid Induced Toxicity.
Topics: Amyloid beta-Peptides; Animals; Bridged-Ring Compounds; Calcium; Cell Death; Cell Line, Tumor; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; Emodin; Hesperidin; Hippocampus; Humans; Ions; Neurons; Neuroprotective Agents; Peptide Fragments; Protein Aggregates; Rats, Sprague-Dawley; Reactive Oxygen Species | 2015 |
Hesperidin from Citrus seed induces human hepatocellular carcinoma HepG2 cell apoptosis via both mitochondrial and death receptor pathways.
Topics: Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; BH3 Interacting Domain Death Agonist Protein; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Citrus; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hesperidin; Humans; Inhibitory Concentration 50; Liver Neoplasms; Mitochondria; Reactive Oxygen Species; Receptors, Death Domain | 2016 |
Low-calorie sweeteners in food and food supplements on the Italian market.
Topics: Aspartame; Chromatography, Liquid; Cyclamates; Diet; Dietary Supplements; Dipeptides; Energy Intake; Food Additives; Food Contamination; Hesperidin; Humans; Italy; Saccharin; Sweetening Agents; Tandem Mass Spectrometry; Thiazines | 2015 |
Application of ionic liquids for elution of bioactive flavonoid glycosides from lime fruit by miniaturized matrix solid-phase dispersion.
Topics: Chromatography, High Pressure Liquid; Citrus aurantiifolia; Flavanones; Fruit; Hesperidin; Imidazoles; Ionic Liquids; Solid Phase Extraction; Solvents | 2016 |
Pure total flavonoids from Citrus paradisi Macfad induce leukemia cell apoptosis in vitro.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Citrus paradisi; Flavanones; Flavonoids; Hesperidin; Humans; Leukemia; Lymphocytes | 2017 |
Purification and characterization of a naringinase from a newly isolated strain of Bacillus amyloliquefaciens 11568 suitable for the transformation of flavonoids.
Topics: Bacillus amyloliquefaciens; beta-Glucosidase; Flavonoids; Fruit and Vegetable Juices; Glycosides; Hesperidin; Hydrolysis; Multienzyme Complexes | 2017 |
Neohesperidin suppresses osteoclast differentiation, bone resorption and ovariectomised-induced osteoporosis in mice.
Topics: Animals; Apoptosis; Blotting, Western; Bone Marrow Cells; Bone Resorption; Calcium; Cathepsin K; Cell Differentiation; Cells, Cultured; Female; Genes, Reporter; Hesperidin; Luciferases; Macrophages; Mice, Inbred C57BL; NF-kappa B; NF-KappaB Inhibitor alpha; NFATC Transcription Factors; Osteoclasts; Osteoporosis; Ovariectomy; Proteolysis; RANK Ligand; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tartrate-Resistant Acid Phosphatase | 2017 |
Neohesperidin Exerts Lipid-Regulating Effects in vitro and in vivo via Fibroblast Growth Factor 21 and AMP-Activated Protein Kinase/Sirtuin Type 1/Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1α Signaling Axis.
Topics: AMP-Activated Protein Kinases; Animals; Body Weight; Dyslipidemias; Fibroblast Growth Factors; Hep G2 Cells; Hesperidin; Humans; Lipid Metabolism; Liver; Mice, Inbred C57BL; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; RNA, Small Interfering; Sirtuin 1 | 2017 |
Investigation of the interaction for three Citrus flavonoids and α-amylase by surface plasmon resonance.
Topics: alpha-Amylases; Biphenyl Compounds; Citrus; Enzymes, Immobilized; Flavanones; Flavonoids; Herb-Drug Interactions; Hesperidin; Kinetics; Picrates; Plant Extracts; Surface Plasmon Resonance | 2017 |
Identification and Comparison of Constituents of Aurantii Fructus and Aurantii Fructus Immaturus by UFLC-DAD-Triple TOF-MS/MS.
Topics: Chromatography, Liquid; Citrus; Drugs, Chinese Herbal; Flavanones; Hesperidin; Mass Spectrometry; Synephrine | 2018 |
Neohesperidin Prevents Aβ
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Brain Ischemia; Hesperidin; Hippocampus; Neurons; Neuroprotective Agents; Peptide Fragments; Protein Disulfide-Isomerases; Rats, Sprague-Dawley | 2018 |
Deep eutectic solvent as a green solvent for enhanced extraction of narirutin, naringin, hesperidin and neohesperidin from Aurantii Fructus.
Topics: Chromatography, High Pressure Liquid; Disaccharides; Flavanones; Green Chemistry Technology; Hesperidin; Hydrogen Bonding; Reference Standards; Solvents; Spectrophotometry, Ultraviolet | 2019 |
Neohesperidin suppresses IgE-mediated anaphylactic reactions and mast cell activation via Lyn-PLC-Ca
Topics: Anaphylaxis; Animals; Disease Models, Animal; Hesperidin; Immunoglobulin E; Male; Mast Cells; Mice | 2019 |
Neohesperidin prevents colorectal tumorigenesis by altering the gut microbiota.
Topics: Animals; Bacteroidetes; Carcinogenesis; Colorectal Neoplasms; Fecal Microbiota Transplantation; Feces; Firmicutes; Gastrointestinal Microbiome; Hesperidin; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbiota; Proteobacteria; RNA, Ribosomal, 16S | 2019 |
Neohesperidin inhibits TGF-β1/Smad3 signaling and alleviates bleomycin-induced pulmonary fibrosis in mice.
Topics: A549 Cells; Animals; Bleomycin; Hesperidin; Humans; Lung; Mice; Myofibroblasts; NIH 3T3 Cells; Pulmonary Fibrosis; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1 | 2019 |
The Anti-Aging Potential of Neohesperidin and Its Synergistic Effects with Other Citrus Flavonoids in Extending Chronological Lifespan of
Topics: Antioxidants; Citrus; Dose-Response Relationship, Drug; Drug Synergism; Flavonoids; Hesperidin; Microbial Viability; Plant Extracts; Reactive Oxygen Species; Saccharomyces cerevisiae | 2019 |
The Effects of Different Varieties of
Topics: Animals; Chromatography, High Pressure Liquid; Depression; Disaccharides; Disease Models, Animal; Drug Synergism; Drugs, Chinese Herbal; Flavanones; Hesperidin; Intestinal Absorption; Iridoids; Male; Rats; Rats, Sprague-Dawley | 2019 |
Comparison of interaction between three similar chalconoids and α-lactalbumin: Impact on structure and functionality of α-lactalbumin.
Topics: Binding Sites; Chalcone; Chalcones; Emulsions; Flavanones; Hesperidin; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lactalbumin; Molecular Docking Simulation; Protein Binding; Protein Conformation, alpha-Helical | 2020 |
Neohesperidin inhibits cardiac remodeling induced by Ang II in vivo and in vitro.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Hesperidin; Hypertrophy, Left Ventricular; Inflammation Mediators; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Application of "spider-web" mode in discovery and identification of Q-markers from Xuefu Zhuyu capsule.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers, Pharmacological; Capsules; Chalcone; Coumaric Acids; Drug Stability; Drugs, Chinese Herbal; Flavanones; Glucosides; Hesperidin; Hydroxybenzoates; Materia Medica; Mice; Monoterpenes; Quality Control; RAW 264.7 Cells | 2020 |
Neohesperidin attenuates obesity by altering the composition of the gut microbiota in high-fat diet-fed mice.
Topics: Animals; Bacteroidetes; Diet, High-Fat; Firmicutes; Gastrointestinal Microbiome; Hesperidin; Male; Mice; Obesity | 2020 |
Application of accelerated solvent extraction coupled with online two-dimensional countercurrent chromatography for continuous extraction and separation of bioactive compounds from Citrus limon peel.
Topics: Animals; Cholinesterase Inhibitors; Citrus; Countercurrent Distribution; Cytochrome P-450 Enzyme System; Disaccharides; Flavanones; Flavonoids; Hesperidin; PC12 Cells; Plant Extracts; Rats; Solvents | 2020 |
Neohesperidin enhances PGC-1α-mediated mitochondrial biogenesis and alleviates hepatic steatosis in high fat diet fed mice.
Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Diet, High-Fat; Fatty Liver; Hep G2 Cells; Hesperidin; Humans; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mitochondria; Non-alcoholic Fatty Liver Disease; Obesity; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | 2020 |
Preparation of crystalline nanocellulose/hydroxypropyl β cyclodextrin/carboxymethyl cellulose polyelectrolyte complexes and their controlled release of neohesperidin-copper (II) in vitro.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Carboxymethylcellulose Sodium; Cellulose; Copper; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Hesperidin; Humans; Hydrogels; Hydrogen-Ion Concentration; MCF-7 Cells; Mechanical Phenomena; Molecular Structure; Polyelectrolytes; Spectroscopy, Fourier Transform Infrared | 2020 |
Surface decoration of neohesperidin-loaded nanoliposome using chitosan and pectin for improving stability and controlled release.
Topics: Adsorption; Chitosan; Delayed-Action Preparations; Drug Stability; Hesperidin; Liposomes; Nanoparticles; Particle Size; Pectins | 2020 |
Neohesperidin Ameliorates Steroid-Induced Osteonecrosis of the Femoral Head by Inhibiting the Histone Modification of lncRNA HOTAIR.
Topics: Animals; Femur Head; Hesperidin; Histones; Male; Mice; Mice, Inbred C57BL; Osteogenesis; RNA, Long Noncoding; Steroids | 2020 |
Multi-target inhibition ability of neohesperidin dictates its neuroprotective activity: Implication in Alzheimer's disease therapeutics.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Cell Line, Tumor; Hesperidin; Humans; Neuroprotective Agents; Peptide Fragments | 2021 |
Neohesperidin alleviated pathological damage and immunological imbalance in rat myocardial ischemia-reperfusion injury via inactivation of JNK and NF-κB p65.
Topics: Animals; Hesperidin; JNK Mitogen-Activated Protein Kinases; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Transcription Factor RelA | 2021 |
Discovery and validation of quality markers of Fructus Aurantii against acetylcholinesterase using metabolomics and bioactivity assays.
Topics: Acetylcholinesterase; Animals; Biomarkers; China; Cholinesterase Inhibitors; Citrus; Coumarins; Drug Discovery; Flavanones; Hesperidin; Male; Metabolomics; Rats; Rats, Sprague-Dawley | 2021 |
Dissection of the potential pharmacological function of neohesperidin dihydrochalcone - a food additive - by in vivo substances profiling and network pharmacology.
Topics: Animals; Chalcones; Disease Models, Animal; Dissection; Food Additives; Hesperidin; Liver; Male; Phosphatidylinositol 3-Kinases; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Suppression of palmitic acid-induced hepatic oxidative injury by neohesperidin-loaded pectin-chitosan decorated nanoliposomes.
Topics: Chitosan; Hesperidin; Humans; Liposomes; Liver; Oxidation-Reduction; Oxidative Stress; Palmitic Acid; Pectins | 2021 |
Neohesperidin promotes the osteogenic differentiation of bone mesenchymal stem cells by activating the Wnt/β-catenin signaling pathway.
Topics: Alkaline Phosphatase; beta Catenin; Bone and Bones; Calcium; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Hesperidin; Humans; Mesenchymal Stem Cells; Osteogenesis; Osteoporosis; Signal Transduction; Wnt Signaling Pathway | 2021 |
UHPLC/MS and NMR-Based Metabolomic Analysis of Dried Water Extract of Citrus-Type Crude Drugs.
Topics: Chromatography, High Pressure Liquid; Citrus; Flavanones; Fruit and Vegetable Juices; Glucose; Hesperidin; Magnetic Resonance Spectroscopy; Metabolomics; Methanol; Plant Extracts; Principal Component Analysis; Sucrose; Tandem Mass Spectrometry; Water | 2021 |
RETRACTED: Empagliflozin and neohesperidin mitigate methotrexate hepatotoxicity via Nrf2/PPARγ/HO-1 signalling initiation and suppression of NF-κB/Keap1/HSP70/caspase-3 axis in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Benzhydryl Compounds; Caspase 3; Chemical and Drug Induced Liver Injury; Glucosides; Heme Oxygenase (Decyclizing); Hesperidin; HSP72 Heat-Shock Proteins; Kelch-Like ECH-Associated Protein 1; Male; Methotrexate; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Protective Agents; Rats; Signal Transduction | 2021 |
Neohesperidin Induces Cell Cycle Arrest, Apoptosis, and Autophagy via the ROS/JNK Signaling Pathway in Human Osteosarcoma Cells.
Topics: Apoptosis; Autophagy; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Hesperidin; Humans; MAP Kinase Signaling System; Osteosarcoma; Reactive Oxygen Species | 2021 |
Empagliflozin and neohesperidin protect against methotrexate-induced renal toxicity via suppression of oxidative stress and inflammation in male rats.
Topics: Acetylcysteine; Animals; Benzhydryl Compounds; Glucosides; Hesperidin; Inflammation; Kidney; Kidney Diseases; Male; Methotrexate; Oxidative Stress; Protective Agents; Rats; Signal Transduction | 2021 |
Neohesperidin promotes the osteogenic differentiation of human bone marrow stromal cells by inhibiting the histone modifications of lncRNA SNHG1.
Topics: Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Hesperidin; Histone Code; Humans; Mesenchymal Stem Cells; Osteogenesis; RNA, Long Noncoding | 2021 |
Therapeutic effect of neohesperidin on TNF-α-stimulated human rheumatoid arthritis fibroblast-like synoviocytes.
Topics: Arthritis, Rheumatoid; Cell Movement; Cell Proliferation; Cells, Cultured; Fibroblasts; Hesperidin; Humans; Synoviocytes; Tumor Necrosis Factor-alpha | 2021 |
Neohesperidin promotes the proliferation and osteogenic differentiation of BMSCs via BMP2-Wnt/β-catenin pathway.
Topics: Animals; beta Catenin; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Proliferation; Cells, Cultured; Hesperidin; Histones; Mesenchymal Stem Cells; Mice; Osteogenesis; Wnt Signaling Pathway | 2022 |
Interaction between pH-shifted ovalbumin and insoluble neohesperidin: Experimental and binding mechanism studies.
Topics: Binding Sites; Circular Dichroism; Hesperidin; Hydrogen-Ion Concentration; Molecular Docking Simulation; Ovalbumin; Protein Binding; Spectrometry, Fluorescence; Thermodynamics | 2022 |
Topics: Accidents, Occupational; Adult; Animals; Anxiety; beta Catenin; Chromatography, High Pressure Liquid; Chronic Disease; Cities; Depression; Drugs, Chinese Herbal; Flavonoids; Heat Stroke; Hesperidin; Humans; Hyperplasia; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-10; Interleukin-6; Kruppel-Like Factor 4; Macrophages, Alveolar; Medical Staff; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Occupational Health; Occupational Injuries; Occupational Stress; Occupations; PPAR gamma; Pulmonary Fibrosis; RNA, Messenger; Sanitation; Silicon Dioxide; Sinusitis; Stress, Psychological; Surveys and Questionnaires; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; X-Box Binding Protein 1; Young Adult | 2022 |
[Determination of neohesperidin and naringin in Qingfei Paidu Granules by RP-HPLC and their transfer rates in preparation process].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Hesperidin | 2022 |
Neohesperidin and spike RBD interaction in omicron and its sub-variants: In silico, structural and simulation studies.
Topics: Computer Simulation; COVID-19; Hesperidin; Humans; SARS-CoV-2 | 2023 |
Preparation of Neohesperidin-Taro Starch Complex as a Novel Approach to Modulate the Physicochemical Properties, Structure and In Vitro Digestibility.
Topics: Colocasia; Hesperidin; Starch; Temperature | 2023 |