hesperidin has been researched along with naringin in 122 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.64) | 18.7374 |
| 1990's | 7 (5.74) | 18.2507 |
| 2000's | 36 (29.51) | 29.6817 |
| 2010's | 62 (50.82) | 24.3611 |
| 2020's | 15 (12.30) | 2.80 |
| Authors | Studies |
|---|---|
| Ash, K; Grohmann, K; Manthey, CL; Manthey, JA; Montanari, A | 1 |
| Bailey, DG; Dawson, PA; Dresser, GK; Freeman, DJ; Kim, RB; Leake, BF; Schwarz, UI | 1 |
| Backleh-Sohrt, M; Ekici, P; Leupold, G; Parlar, H | 1 |
| Bronze, MR; Mendes, T; Serra, H; Simplício, AL | 1 |
| Amić, D; Lucić, B | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Carbajo, RJ; Gozalbes, R; Melnyk, P; Mosulén, S; Ortí, L; Pineda-Lucena, A; Rodríguez-Díaz, J | 1 |
| Bijak, M; Krotkiewski, H; Nowak, P; Pawlaczyk, I; Ponczek, M; Saluk, J; Wachowicz, B; Ziewiecki, R | 1 |
| Kroyer, G | 1 |
| Estienne, J; Gaydou, EM; Mouly, P | 1 |
| Ameer, B; Johnson, JV; Rouseff, RL; Weintraub, RA; Yost, RA | 1 |
| Calomme, M; Pieters, L; Vanden Berghe, D; Vlietinck, A | 1 |
| Kometani, T; Nakae, T; Nishimura, T; Okada, S; Takii, H | 1 |
| Aida, K; Kawaguchi, K; Mizuno, T; Uchino, K | 1 |
| de Graaff, LH; Manzanares, P; Visser, J | 1 |
| Bronnenmeier, K; Hertel, C; Hroch, A; Kellermann, J; Schwarz, WH; Zverlov, VV | 1 |
| Carrillo, L; Cuevas, C; Ellenrieder, G; Scaroni, E | 1 |
| Li, L; Li, XL; Liang, XM; Xiao, HB | 1 |
| Gabrieli, C; Georgarakis, M; Kanaze, FI; Kokkalou, E; Niopas, I | 1 |
| FREEDMAN, L; MERRITT, AJ | 1 |
| Chen, YC; Lin, HY; Shen, SC | 1 |
| Li, X; Liang, X; Liu, J; Shi, D; Xiao, H | 1 |
| Arcas, MC; Baidez, AG; Botía, JM; del Río, JA; Gómez, P; Ortuño, A | 1 |
| Kurowska, EM; Manthey, JA | 1 |
| Georgarakis, M; Kanaze, FI; Kokkalou, E; Niopas, I | 1 |
| Hwang, IK; Lee, HJ; Lee, KW; Park, JB; Yoo, KM | 1 |
| Choi, MS; Jeong, KS; Jung, UJ; Lee, MK | 1 |
| Cheng, YY; Huang, ZF; Luan, LJ; Shao, Q | 1 |
| De Rossi, A; Desiderio, C; Sinibaldi, M | 1 |
| Liu, F; Peng, Y; Ye, J | 1 |
| Choi, MS; Jung, UJ; Kang, MA; Lee, MK; Park, YB | 1 |
| Clowers, BH; Hill, HH | 1 |
| Liang, XM; Xu, Q; Xue, XY; Zhang, FF; Zhou, DY | 1 |
| Asztemborska, M; Zukowski, J | 1 |
| Li, K; Su, W; Yuan, J | 1 |
| Li, LF; Liu, ZL; Song, ZQ; Wang, YS; Zhang, L | 1 |
| Bailey, DG; Dresser, GK; Kim, RB; Leake, BF | 1 |
| Goda, Y; Kawahara, N; Kikura-Hanajiri, R; Kim, IH; Konishi, T; Uchiyama, N | 1 |
| Ding, L; Liu, Q; Luo, X; Tang, F; Yao, S; Yuan, J | 1 |
| Go, YH; Kim, TK; Lee, KW; Lee, YH | 1 |
| Bourland, TC; Miller, EG; Patil, BS; Peacock, JJ; Taylor, SE; Wright, JM | 1 |
| Fujii, T; Handa, T; Iefuji, H; Koseki, T; Masaki, K; Mese, Y; Murayama, T; Nishibori, N; Shiono, Y; Yamane, Y | 1 |
| Ignatowicz, E; Zielińska-Przyjemska, M | 1 |
| Gabrieli, C; Georgarakis, M; Kanaze, FI; Kokkalou, E; Niopas, I; Termentzi, A | 1 |
| Chen, S; Gu, X; Huang, X; Qin, F; Ren, P; Zhang, H | 1 |
| Iqbal, MF; Zhu, WY | 1 |
| Chen, JC; He, YC; Li, LJ; Liu, HX; Wen, SM; Zheng, QS | 1 |
| Itoh, K; Masuda, M; Matsuda, H; Murata, K; Naruto, S | 1 |
| Kumar, A; Kumar, P | 1 |
| Caccamese, S; Chillemi, R | 1 |
| Chen, GY; Gong, HL; Huang, X; Liang, MZ; Tang, WF; Xia, Q; Xiang, J; Yu, Q | 1 |
| Belboukhari, N; Cheriti, A; Roussel, C; Vanthuyne, N | 1 |
| Demonty, I; Jäkel, M; Lin, Y; Trautwein, EA; van der Knaap, HC; Vermeer, MA; Zebregs, YE | 1 |
| Fu, H; Fujii, K; Hata, K; Katsumura, Y; Lin, M; Muroya, Y; Shikazono, N; Yokoya, A | 1 |
| Di, L; Guo, Q; Wang, J; Wang, S; Wu, X; Zhang, X; Zhao, X | 1 |
| Jain, M; Parmar, HS | 1 |
| Cavalitto, SF; Hours, RA; Rojas, NL; Voget, CE | 1 |
| Cheng, K; Xu, D | 1 |
| Kaats, GR; Keith, PL; Keith, SC; Miller, H; Preuss, HG; Stohs, SJ | 1 |
| Breadmore, MC; Li, Y; Lu, Y; Yao, Q; Zhong, H | 1 |
| Dejaegher, B; Fan, G; Frédérich, M; Szandrach, A; Thierry, L; Tistaert, C; Vander Heyden, Y | 1 |
| Chung, IM; Jung, YS; Park, SW; Yu, HY | 1 |
| Freuchet, B; Jeusette, I; Le Bloc'h, J; Leray, V; Nguyen, P; Torre, C | 1 |
| Bi, K; Gao, J; Sun, H; Tong, L; Zhou, D; Zhu, Y | 1 |
| Kim, CE; Kim, MH; Kim, SW | 1 |
| Abubakar, S; Mustafa, MR; Sam, SS; Teoh, BT; Wong, PF; Zandi, K | 1 |
| Giddings, JC; Ikemura, M; Sasaki, Y; Yamamoto, J | 1 |
| Duan, JA; Lu, LL; Qian, DW; Qian, YF; Shu, Y; Su, SL; Xue, CF | 1 |
| Feng, X; Jin, F; Liu, T; Lu, M; Ma, A; Mukai, C; Ohba, M; Piao, Y; Qin, S; Tang, M; Tsuji, A; Wang, K; Wei, S; Yu, H; Yuan, X; Zhang, C | 1 |
| Aguilar, JA; Cassani, J; Colbourne, AA; Morris, GA; Nilsson, M | 1 |
| Chen, X; Huang, W; Huang, X; Liu, WP; Ren, P; Wang, Y; Xiong, ZH | 1 |
| Chen, GY; Gong, HL; Huang, X; Tang, WF; Wang, J | 1 |
| Chen, K; Chen, Q; Li, X; Luo, F; Sun, C; Yan, Y; Zhang, J; Zhu, X | 1 |
| Balasubramaniam, VM; Jayaprakasha, GK; Patil, BS; Uckoo, RM | 1 |
| Lu, YH; Shen, W; Xu, Y | 1 |
| Mori, T; Nakanishi, T; Shichiri, M; Shirasaka, Y; Tamai, I | 1 |
| Bonzi-Coulibaly, YL; Gerbaux, P; Ilboudo, O; Tapsoba, I | 1 |
| Fujimoto, Z; Ichinose, H; Kaneko, S | 1 |
| Chen, J; Jiang, P; Qiao, L; Shen, Y; Sun, Y; Ye, X | 1 |
| Chen, G; Gong, H; Tang, W; Wang, J; Xiang, J; Zhao, J | 1 |
| Nam, HK; Oh, DK; Shin, KC | 1 |
| Buachan, P; Chularojmontri, L; Wattanapitayakul, SK | 1 |
| Ge, SB; Hou, ZS; Pan, JH; Yan, GJ | 1 |
| Du, Y; Fu, Y; Liu, H; Liu, Y; Ma, K; Song, Y; Sun, T; Sun, Y; Wang, K; Wen, X; Wu, J; Zhang, F; Zhang, L; Zhang, Y; Zhao, Z | 1 |
| Kar, A; Panda, S | 1 |
| Chang, YS; Chen, P; Zhao, Y | 1 |
| Banjerdpongchai, R; Duangnil, N; Khaw-On, P; Kongtawelert, P; Rachakhom, W; Wudtiwai, B | 1 |
| Charismiadou, MA; Deligeorgis, SG; Goliomytis, M; Kartsonas, N; Simitzis, PE; Symeon, GK | 1 |
| Cao, J; Cao, W; Hu, SS; Peng, LQ; Xu, JJ; Yang, R; Ye, LH | 1 |
| Dai, TY; Jiang, JP; Lin, SY; Qian, WB; Wang, B; Wu, LQ | 1 |
| Johnson, EJ; Köck, K; Paine, MF; Won, CS | 1 |
| Charismiadou, M; Deligeorgis, SG; Fotakis, C; Goliomytis, M; Lantzouraki, DZ; Simitzis, PE; Zoumpoulakis, P | 1 |
| LeBlanc, PJ; Sacco, SM; Saint, C; Ward, WE | 1 |
| Li, J; Li, JY; Ren, HY; Su, H; Tang, WF; Wu, FS; Zhang, YM; Zhao, XL | 1 |
| Gao, W; Li, P; Liu, X; Luo, F; She, Y | 1 |
| Dokumacioglu, E; Hayirli, A; Iskender, H; Kaya, A; Kaynar, O; Yenice, G | 1 |
| Bai, Y; Cheng, J; Deng, W; Li, P; Pang, W; Peng, W; Su, W; Wu, H; Yao, H; Zheng, Y | 1 |
| Charalambous, A; Charismiadou, MA; Deligeorgis, SG; Giamouri, E; Goliomytis, M; Ntetska, I; Simitzis, PE | 1 |
| Buszman, E; Iriti, M; Kabała-Dzik, A; Kubina, R; Rzepecka-Stojko, A; Stojko, J; Wojtyczka, RD | 1 |
| Baira, E; Dagla, I; Deligeorgis, SG; Gikas, E; Goliomytis, M; Siapi, E; Simitzis, P; Skaltsounis, AL; Zoumpoulakis, P | 1 |
| Chen, D; Guo, S; Liu, Y; Yu, H; Zhang, H | 1 |
| Adorno, MAT; Cecatti, C; Cesar, TB; Fidélix, MP; Lima, ACD; Sakamoto, IK; Sivieri, K | 1 |
| Anwar, A; Khan, NA; Masri, A; Rajendran, K; Rao, K; Shah, MR; Siddiqui, R | 1 |
| Charismiadou, MA; Deligeorgis, SG; Goliomytis, M; Hager-Theodorides, AL; Papalexi, A; Simitzis, P; Veneti, N | 1 |
| Cesar, TB; Manthey, JA; Ramos, FM; Ribeiro, CB | 1 |
| Charismiadou, M; Deligeorgis, S; Economou, C; Goliomytis, M; Lepesioti, S; Massouras, T; Moschou, K; Papadedes, V; Simitzis, P | 1 |
| Baira, E; Dagla, I; Deligeorgis, SG; Gikas, E; Goliomytis, M; Siapi, E; Simitzis, P; Skaltsounis, AL; Tsarbopoulos, A; Zoumpoulakis, P | 1 |
| Feng, F; Zhang, Q | 1 |
| Cai, X; Huang, D; Lei, Y; Lin, M; Luo, K; Sun, Z; Tan, S; Wang, Y; Xia, X; Yan, J; Zhang, Y | 1 |
| Abdul, Q; Chen, W; Hou, J; Jiang, Z; Li, T; Ma, L; Tian, B; Yu, H | 1 |
| Kaur, A; Singh, B; Singh, JP; Singh, N | 1 |
| Chai, X; Wang, D; Wang, Y; Yang, J; Zhang, J; Zhang, X | 1 |
| Li, S; Liu, C; Shi, D; Tsao, R; Zhang, Y | 1 |
| Antony, PJ; Gan, RY; Gandhi, GR; Geng, F; Gurgel, RQ; Li, H; Li, HB; Narain, N; Vasconcelos, ABS; Wu, DT | 1 |
| Dai, MY; Li, F; Liu, HN; Ma, XF; Wang, YK; Xiao, XR; Zhang, SW; Zhou, ZM | 1 |
| Jagetia, GC; Lalrinzuali, K; Vabeiryureilai, M | 1 |
| Arai, R; Hakamatsuka, T; Ozeki, Y; Tsujimoto, T; Uchiyama, N; Yamamoto, Y; Yoshitomi, T | 1 |
| Abo Sree, HT; Ahmed, OM; Al-Muzafar, HM; Amin, KA; Hassan, RA; Hozayen, WG | 1 |
| Garofalo, A; Grande, F; Ioele, G; Occhiuzzi, MA; Perri, MR; Rizzuti, B; Statti, G | 1 |
| Ahles, S; Sost, MM; Stevens, Y; Venema, K; Verbruggen, S; Verhoeven, J | 1 |
| Cao, X; Fang, X; Guo, A; Guo, X; Li, E | 1 |
| Bian, BL; Han, L; Li, ML; Si, N; Wang, HJ; Wu, HK; Yang, LX; Zhang, Y; Zhao, HY; Zhou, YY; Zhu, HY | 1 |
2 review(s) available for hesperidin and naringin
| Article | Year |
|---|---|
Phenolic composition, antioxidant potential and health benefits of citrus peel.
Topics: Antioxidants; Biological Availability; Citrus; Coumaric Acids; Flavanones; Flavones; Fruit; Hesperidin; Hydroxybenzoates; Phenols; Plant Extracts; Polyphenols | 2020 |
Citrus Flavonoids as Promising Phytochemicals Targeting Diabetes and Related Complications: A Systematic Review of In Vitro and In Vivo Studies.
Topics: Animals; Antioxidants; Citrus; Diabetes Mellitus; Disaccharides; Flavanones; Flavones; Flavonoids; Glycosides; Hesperidin; Humans; Inflammation; Phytochemicals; Polyphenols; Propiophenones | 2020 |
7 trial(s) available for hesperidin and naringin
| Article | Year |
|---|---|
Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.
Topics: Administration, Oral; Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Beverages; Biological Availability; Carrier Proteins; Citrus; Double-Blind Method; Female; Flavonoids; Food-Drug Interactions; Fruit; HeLa Cells; Histamine H1 Antagonists; Humans; Intestinal Absorption; Male; Malus; Membrane Transport Proteins; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Symporters; Terfenadine | 2002 |
Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice.
Topics: Adult; Anticoagulants; Beverages; Citrus paradisi; Cross-Over Studies; Data Interpretation, Statistical; Double-Blind Method; Drug Interactions; Female; Flavanones; Furocoumarins; HeLa Cells; Hesperidin; Histamine H1 Antagonists; Humans; Male; Middle Aged; Organic Anion Transporters; Reproducibility of Results; Terfenadine | 2007 |
The citrus flavonoids hesperidin and naringin do not affect serum cholesterol in moderately hypercholesterolemic men and women.
Topics: Aged; Cholesterol; Citrus; Female; Flavanones; Hesperidin; Humans; Hypercholesterolemia; Hypolipidemic Agents; Male; Middle Aged | 2010 |
Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes.
Topics: Analysis of Variance; Blood Pressure; Flavanones; Flavonoids; Heart Rate; Hesperidin; Humans; Synephrine | 2011 |
Effect of citrus polyphenol- and curcumin-supplemented diet on inflammatory state in obese cats.
Topics: Acute-Phase Proteins; Animals; Cat Diseases; Cats; Citrus; Cross-Over Studies; Curcumin; Cytokines; Female; Flavanones; Gene Expression Regulation; Hesperidin; Inflammation; Leukocytes, Mononuclear; Male; Obesity; RNA, Messenger | 2011 |
Effect of Daily Consumption of Orange Juice on the Levels of Blood Glucose, Lipids, and Gut Microbiota Metabolites: Controlled Clinical Trials.
Topics: Adult; Bifidobacterium; Biomarkers; Blood Glucose; Cholesterol, LDL; Citrus sinensis; Diet; Feeding Behavior; Female; Flavanones; Fruit; Fruit and Vegetable Juices; Gastrointestinal Microbiome; Hesperidin; Humans; Insulin; Insulin Resistance; Intestines; Lactobacillus; Lipids; Polymerase Chain Reaction; Reference Values; Young Adult | 2019 |
Effectiveness of Eriomin® in managing hyperglycemia and reversal of prediabetes condition: A double-blind, randomized, controlled study.
Topics: Adult; Blood Glucose; Citrus; Double-Blind Method; Female; Flavanones; Glycated Hemoglobin; Hesperidin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Male; Middle Aged; Prediabetic State; Treatment Outcome | 2019 |
113 other study(ies) available for hesperidin and naringin
| Article | Year |
|---|---|
Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human monocytes.
Topics: Citrus; Cyclic AMP; Flavonoids; Humans; In Vitro Techniques; Lipopolysaccharides; Monocytes; Phosphodiesterase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 1999 |
Efficiency of foam fractionation for the enrichment of nonpolar compounds from aqueous extracts of plant materials.
Topics: Carotenoids; Chemical Fractionation; Chromatography, High Pressure Liquid; Citrus; Curcuma; Curcumin; Cyclohexenes; Daucus carota; Flavanones; Hesperidin; Molecular Structure; Plant Extracts; Tea; Terpenes; Water | 2005 |
Prediction of intestinal absorption and metabolism of pharmacologically active flavones and flavanones.
Topics: Caco-2 Cells; Electrophoresis, Capillary; Flavanones; Flavones; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Molecular Structure; Molecular Weight | 2008 |
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics | 2010 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Hit identification of novel heparanase inhibitors by structure- and ligand-based approaches.
Topics: Amodiaquine; Antimalarials; Binding Sites; Catalytic Domain; Drug Design; Glucuronidase; Humans; Ligands; Molecular Docking Simulation; Nuclear Magnetic Resonance, Biomolecular; Quantitative Structure-Activity Relationship; Recombinant Proteins; Structure-Activity Relationship | 2013 |
Thrombin inhibitory activity of some polyphenolic compounds.
Topics: | 2014 |
[The antioxidant activity of citrus fruit peels].
Topics: Antioxidants; Ascorbic Acid; Citrus; Flavanones; Flavonoids; Freeze Drying; Hesperidin; Vitamin E | 1986 |
Column liquid chromatographic determination of flavanone glycosides in Citrus. Application to grapefruit and sour orange juice adulterations.
Topics: Beverages; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Citrus; Flavanones; Flavonoids; Hesperidin; Molecular Sequence Data; Quality Control | 1993 |
Flavanone absorption after naringin, hesperidin, and citrus administration.
Topics: Adult; Beverages; Citrus; Flavanones; Flavonoids; Hesperidin; Humans; Intestinal Absorption; Male; Mass Spectrometry | 1996 |
Inhibition of bacterial mutagenesis by Citrus flavonoids.
Topics: Anticarcinogenic Agents; Antimutagenic Agents; Antioxidants; Benzo(a)pyrene; Citrus; Diet; Flavanones; Flavones; Flavonoids; Hesperidin; Humans; Mutagenicity Tests; Mutagens; Salmonella typhimurium | 1996 |
Synthesis of neohesperidin glycosides and naringin glycosides by cyclodextrin glucanotransferase from an alkalophilic Bacillus species.
Topics: Alkalies; Bacillus; Carbon Isotopes; Flavanones; Flavonoids; Glucosyltransferases; Glycosides; Glycosylation; Hesperidin; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Structure; Protons; Solubility; Taste | 1996 |
Hesperidin as an inhibitor of lipases from porcine pancreas and Pseudomonas.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Citrus; Eating; Enzyme Inhibitors; Feces; Flavanones; Flavonoids; Hesperidin; Lipase; Lipid Metabolism; Lipids; Pancreas; Pseudomonas; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Triglycerides; Weight Gain | 1997 |
Purification and characterization of an alpha-L-rhamnosidase from Aspergillus niger.
Topics: Aspergillus niger; Carbohydrate Conformation; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Flavanones; Flavonoids; Fungal Proteins; Glucosides; Glycoside Hydrolases; Hesperidin; Kinetics; Molecular Weight; Rhamnose; Rosales; Rutin; Substrate Specificity; Wine | 1997 |
The thermostable alpha-L-rhamnosidase RamA of Clostridium stercorarium: biochemical characterization and primary structure of a bacterial alpha-L-rhamnoside hydrolase, a new type of inverting glycoside hydrolase.
Topics: Amino Acid Sequence; Circular Dichroism; Cloning, Molecular; Clostridium; DNA, Recombinant; Enzyme Stability; Flavanones; Flavonoids; Glycoside Hydrolases; Glycosides; Hesperidin; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Temperature | 2000 |
Hydrolytic properties of crude alpha-L-rhamnosidases produced by several wild strains of mesophilic fungi.
Topics: Aspergillus; Flavanones; Flavonoids; Fusarium; Glycoside Hydrolases; Hesperidin; Hydrogen-Ion Concentration; Hydrolysis; Mucor; Temperature; Trichoderma | 2002 |
[Determination of hesperidin and naringin in Fructus Aurantii Immaturus and Fructus Aurantii by reversed-phase high performance liquid chromatography].
Topics: Chromatography, High Pressure Liquid; Citrus; Drugs, Chinese Herbal; Flavanones; Flavonoids; Hesperidin | 2002 |
Simultaneous reversed-phase high-performance liquid chromatographic method for the determination of diosmin, hesperidin and naringin in different citrus fruit juices and pharmaceutical formulations.
Topics: Antioxidants; Beverages; Chromatography, High Pressure Liquid; Citrus; Diosmin; Flavanones; Flavonoids; Hesperidin; Indicators and Reagents; Reference Standards; Solutions; Spectrophotometry, Ultraviolet; Tablets | 2003 |
Citrus flavonoid complex: chemical fractionation and biological activity.
Topics: Anti-Inflammatory Agents; Chemical Fractionation; Citrus; Edema; Flavanones; Flavonoids; Fruit; Hesperidin; Inflammation | 1963 |
Rutinoside at C7 attenuates the apoptosis-inducing activity of flavonoids.
Topics: Apoptosis; beta-Glucosidase; Caspase 1; Caspase 3; Caspases; Drug Interactions; Flavanones; Flavonoids; Glycoside Hydrolases; Guanine Nucleotide Dissociation Inhibitors; Hesperidin; HL-60 Cells; Humans; Multienzyme Complexes; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Neutrophils; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; rho Guanine Nucleotide Dissociation Inhibitor beta; rho-Specific Guanine Nucleotide Dissociation Inhibitors | 2003 |
LC-MS/MS determination of naringin, hesperidin and neohesperidin in rat serum after orally administrating the decoction of Bulpleurum falcatum L. and Fractus aurantii.
Topics: Administration, Oral; Animals; Chromatography, Liquid; Drugs, Chinese Herbal; Flavanones; Hesperidin; Mass Spectrometry; Rats; Rats, Wistar | 2004 |
Changes in the levels of polymethoxyflavones and flavanones as part of the defense mechanism of Citrus sinensis (cv. Valencia Late) fruits against Phytophthora citrophthora.
Topics: Citrus sinensis; Flavanones; Flavonoids; Fruit; Fungicides, Industrial; Hesperidin; Phytophthora; Plant Diseases | 2004 |
Hypolipidemic effects and absorption of citrus polymethoxylated flavones in hamsters with diet-induced hypercholesterolemia.
Topics: Absorption; Animals; Citrus; Cricetinae; Diet; Flavanones; Flavones; Flavonoids; Hesperidin; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Liver; Male; Mesocricetus | 2004 |
A validated solid-phase extraction HPLC method for the simultaneous determination of the citrus flavanone aglycones hesperetin and naringenin in urine.
Topics: Calibration; Chromatography, High Pressure Liquid; Citrus; Flavanones; Hesperidin; Humans; Molecular Structure; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling | 2004 |
Variation in major antioxidants and total antioxidant activity of Yuzu (Citrus junos Sieb ex Tanaka) during maturation and between cultivars.
Topics: Antioxidants; Ascorbic Acid; Citrus; Flavanones; Fruit; Hesperidin; Phenols | 2004 |
The hypoglycemic effects of hesperidin and naringin are partly mediated by hepatic glucose-regulating enzymes in C57BL/KsJ-db/db mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Flavanones; Glucokinase; Gluconeogenesis; Glucose-6-Phosphatase; Hesperidin; Hypoglycemic Agents; Insulin; Liver; Male; Mice; Pancreas | 2004 |
[Study on quality control of effective fraction in qixue bingzhi decoction].
Topics: Benzoates; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Flavanones; Glucosides; Hesperidin; Ligusticum; Monoterpenes; Paeonia; Plants, Medicinal; Quality Control; Reproducibility of Results | 2005 |
Analysis of flavanone-7-O-glycosides in citrus juices by short-end capillary electrochromatography.
Topics: Acetonitriles; Beverages; Chromatography, High Pressure Liquid; Citrus; Disaccharides; Electrophoresis, Capillary; Flavanones; Formates; Glycosides; Hesperidin; Reproducibility of Results | 2005 |
Quantitative and qualitative analysis of flavonoid markers in Frucus aurantii of different geographical origin by capillary electrophoresis with electrochemical detection.
Topics: Buffers; China; Citrus; Electrochemistry; Electrodes; Electrophoresis, Capillary; Flavanones; Flavonoids; Fruit; Hesperidin; Hydrogen-Ion Concentration; Reproducibility of Results; Synephrine; Time Factors | 2006 |
Effect of citrus flavonoids on lipid metabolism and glucose-regulating enzyme mRNA levels in type-2 diabetic mice.
Topics: Animals; Citrus; Diabetes Mellitus, Type 2; Flavanones; Glucokinase; Hesperidin; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Phytotherapy; RNA, Messenger | 2006 |
Influence of cation adduction on the separation characteristics of flavonoid diglycoside isomers using dual gate-ion mobility-quadrupole ion trap mass spectrometry.
Topics: Cations; Disaccharides; Flavanones; Flavonoids; Glycosides; Hesperidin; Isomerism; Potassium; Protons; Rutin; Sodium; Spectrometry, Mass, Electrospray Ionization | 2006 |
Identification of O-diglycosyl flavanones in Fructus aurantii by liquid chromatography with electrospray ionization and collision-induced dissociation mass spectrometry.
Topics: Chromatography, Liquid; Citrus; Flavanones; Fruit; Glycosides; Hesperidin; Molecular Structure; Spectrometry, Mass, Electrospray Ionization | 2006 |
Determination of diastereomerization barrier of some flavanones by high-performance liquid chromatography methods.
Topics: Chromatography, High Pressure Liquid; Disaccharides; Flavanones; Flavonoids; Hesperidin; Kinetics; Stereoisomerism | 2006 |
Determination of liquiritin, naringin, hesperidin, thymol, imperatorin, honokiol, isoimperatorin, and magnolol in the traditional Chinese medicinal preparation Huoxiang-zhengqi liquid using high-performance liquid chromatography.
Topics: Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Furocoumarins; Glucosides; Hesperidin; Lignans; Reproducibility of Results; Solutions; Thymol | 2006 |
[Determination of three chemical components in Fructus aurantii immaturus].
Topics: China; Chromatography, High Pressure Liquid; Citrus; Ecosystem; Flavanones; Fruit; Hesperidin; Oils, Volatile; Plants, Medicinal; Quality Control; Synephrine | 2006 |
HPLC separation of naringin, neohesperidin and their C-2 epimers in commercial samples and herbal medicines.
Topics: Cellulose; Chromatography, High Pressure Liquid; Citrus; Flavanones; Hesperidin; Medicine, Kampo; Phenylcarbamates; Plant Preparations; Stereoisomerism; Technology, Pharmaceutical | 2008 |
Simultaneous determination of flavonoid and alkaloid compounds in Citrus herbs by high-performance liquid chromatography-photodiode array detection-electrospray mass spectrometry.
Topics: Alkaloids; Chromatography, High Pressure Liquid; Citrus; Drugs, Chinese Herbal; Flavanones; Flavonoids; Fluorocarbons; Hesperidin; Light; Microwaves; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Synephrine | 2007 |
Functional characteristics of cyclodextrin glucanotransferase from alkalophilic Bacillus sp. BL-31 highly specific for intermolecular transglycosylation of bioflavonoids.
Topics: Bacillus; Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Glucosyltransferases; Glycosylation; Hesperidin; Molecular Structure; Rutin | 2007 |
Inhibition of oral carcinogenesis by citrus flavonoids.
Topics: Animals; Antineoplastic Agents; Cell Division; Chromatography, High Pressure Liquid; Citrus; Cricetinae; Flavanones; Flavones; Flavonoids; Hesperidin; Mouth Neoplasms; Random Allocation | 2008 |
Characterization of an alpha-L-rhamnosidase from Aspergillus kawachii and its gene.
Topics: Aspergillus; DNA, Fungal; Enzyme Stability; Flavanones; Glycoside Hydrolases; Glycosylation; Hesperidin; Hydrogen-Ion Concentration; Molecular Sequence Data; Molecular Weight; Rhamnose; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Substrate Specificity; Temperature; Transition Temperature | 2008 |
Citrus fruit flavonoids influence on neutrophil apoptosis and oxidative metabolism.
Topics: Analysis of Variance; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Caspase 3; Cell Survival; Cells, Cultured; Citrus; Flavanones; Hesperidin; Humans; Luminescence; Luminol; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 2008 |
The phytochemical analysis and antioxidant activity assessment of orange peel (Citrus sinensis) cultivated in Greece-Crete indicates a new commercial source of hesperidin.
Topics: Antioxidants; Biphenyl Compounds; Chromatography, Liquid; Citrus sinensis; Diosmin; Flavanones; Greece; Hesperidin; Luminescent Measurements; Luminol; Methanol; Models, Chemical; Picrates; Plant Extracts; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2009 |
Simultaneous determination of 12 chemical constituents in the traditional Chinese Medicinal Prescription Xiao-Yao-San-Jia-Wei by HPLC coupled with photodiode array detection.
Topics: Acetophenones; Benzoates; Biphenyl Compounds; Bridged-Ring Compounds; Coumaric Acids; Drugs, Chinese Herbal; Flavanones; Glucosides; Glycyrrhizic Acid; Hesperidin; Iridoids; Isoflavones; Lignans; Medicine, Chinese Traditional; Molecular Structure; Monoterpenes; Quality Control; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2008 |
Bioactivation of flavonoid diglycosides by chicken cecal bacteria.
Topics: Animals; Biotransformation; Carboxylic Acids; Cecum; Chickens; Cluster Analysis; DNA, Bacterial; DNA, Ribosomal; Flavanones; Flavonoids; Hesperidin; Lactobacillus; Maltose; Molecular Sequence Data; Phylogeny; RNA, Ribosomal, 16S; Rutin; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid | 2009 |
[Anti-inflammatory effects and quantitative study of the combinations of active ingredients of Painong powder in mice].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bridged-Ring Compounds; Drug Evaluation, Preclinical; Drug Synergism; Drugs, Chinese Herbal; Female; Flavanones; Glucosides; Hesperidin; Male; Mice; Monoterpenes; Powders; Saponins | 2009 |
Antiallergic activity of unripe Citrus hassaku fruits extract and its flavanone glycosides on chemical substance-induced dermatitis in mice.
Topics: Animals; Anti-Allergic Agents; Cells, Cultured; Citrus; Dermatitis, Contact; Female; Flavanones; Hesperidin; Histamine; Mast Cells; Mice; Mice, Inbred BALB C; Picryl Chloride; Plant Extracts; Prednisolone; Rats | 2009 |
Protective effect of hesperidin and naringin against 3-nitropropionic acid induced Huntington's like symptoms in rats: possible role of nitric oxide.
Topics: Analysis of Variance; Animals; Antioxidants; Body Weight; Catalase; Corpus Striatum; Disease Models, Animal; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex IV; Flavanones; Hand Strength; Hesperidin; Huntington Disease; Lipid Peroxidation; Male; Mitochondria; Motor Activity; Nitric Oxide; Nitrites; Nitro Compounds; Propionates; Rats; Rats, Wistar; Rotarod Performance Test; Superoxide Dismutase | 2010 |
Racemization at C-2 of naringin in pummelo (Citrus grandis) with increasing maturity determined by chiral high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Citrus; Flavanones; Flavonoids; Fruit; Hesperidin; Plant Extracts; Stereoisomerism | 2010 |
Effect of severe acute pancreatitis on pharmacokinetics of Da-Cheng-Qi Decoction components.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Enzyme Inhibitors; Flavanones; Glucosides; Hesperidin; Humans; Lignans; Male; Molecular Structure; Mutagens; Pancreatitis, Acute Necrotizing; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley | 2009 |
Chiral separation of hesperidin and naringin and its analysis in a butanol extract of Launeae arborescens.
Topics: Asteraceae; Butanols; Chromatography, High Pressure Liquid; Flavanones; Hesperidin; Palmitic Acid; Plant Extracts | 2010 |
Protective effects of silybin and analogues against X-ray radiation-induced damage.
Topics: Antioxidants; DNA; DNA Breaks, Single-Stranded; DNA Damage; Dose-Response Relationship, Radiation; Electrophoresis, Agar Gel; Flavanones; Hesperidin; Models, Chemical; Molecular Structure; Plasmids; Silybin; Silymarin | 2010 |
[Simultaneous determination of chlorogenic acid, cryptochlorogenic acid, caffeic acid, naringin, hesperidin and linarin in xiao'erjinning oral liquid by an HPLC method].
Topics: Caffeic Acids; Chlorogenic Acid; Chromatography, High Pressure Liquid; Dosage Forms; Drugs, Chinese Herbal; Flavanones; Glycosides; Hesperidin | 2010 |
Evaluation of antioxidative and anti-inflammatory potential of hesperidin and naringin on the rat air pouch model of inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Catalase; Edema; Flavanones; Free Radical Scavengers; Glutathione; Hesperidin; Indomethacin; Inflammation; Leukocytes; Lipid Peroxidation; Male; Neutrophils; Oxidative Stress; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2011 |
Purification and characterization of a novel alkaline α-L-rhamnosidase produced by Acrostalagmus luteo albus.
Topics: Ascomycota; Biocatalysis; Electrophoresis, Polyacrylamide Gel; Flavanones; Glucosides; Glycoside Hydrolases; Hesperidin; Hydrolysis; Molecular Weight; Rhamnose; Substrate Specificity; Temperature | 2011 |
[Determination of liquiritin, naringin, hesperidin and glycyrrhizic acid in extractive of Wendan formula by RP-HPLC].
Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drugs, Chinese Herbal; Flavanones; Glucosides; Glycyrrhizic Acid; Hesperidin | 2011 |
Analysis of flavonoids by capillary zone electrophoresis with electrokinetic supercharging.
Topics: Clematis; Electrophoresis, Capillary; Flavanones; Flavonoids; Hesperidin; Sensitivity and Specificity; Taurine | 2011 |
Quality control of Citri reticulatae pericarpium: exploratory analysis and discrimination.
Topics: Chromatography, High Pressure Liquid; Citrus; Discriminant Analysis; Drugs, Chinese Herbal; Flavanones; Flavones; Hesperidin; Least-Squares Analysis; Polymerase Chain Reaction; Quality Control | 2011 |
Anti-platelet effects of yuzu extract and its component.
Topics: Administration, Oral; Animals; Arachidonic Acid; Bleeding Time; Blood Platelets; Citrus; Collagen; Flavanones; Fruit; Hesperidin; Male; Mice; Mice, Inbred ICR; Plant Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombin | 2011 |
Simultaneous determination of naringin, hesperidin, neohesperidin, naringenin and hesperetin of Fractus aurantii extract in rat plasma by liquid chromatography tandem mass spectrometry.
Topics: Animals; Chromatography, Liquid; Flavanones; Fruit; Glucosides; Hesperidin; Male; Rats; Rats, Wistar; Reference Standards; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2012 |
Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells.
Topics: Anthracenes; Butadienes; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Flavanones; Glucose; Hesperidin; Humans; Hyperglycemia; Imidazoles; Intercellular Adhesion Molecule-1; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Resveratrol; Stilbenes; Up-Regulation; Veins | 2011 |
Antiviral activity of four types of bioflavonoid against dengue virus type-2.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Dengue; Dengue Virus; Flavanones; Flavonoids; Flavonols; Hesperidin; Inhibitory Concentration 50; Phytotherapy; Quercetin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Vero Cells; Virus Replication | 2011 |
Preventive effects of hesperidin, glucosyl hesperidin and naringin on hypertension and cerebral thrombosis in stroke-prone spontaneously hypertensive rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Body Weight; Deoxyguanosine; Flavanones; Glucosides; Hesperidin; Hypertension; Intracranial Thrombosis; Male; Nitric Oxide; Oxidative Stress; Rats; Rats, Inbred SHR; Vasodilation | 2012 |
[Identification of the metabolites of Sinisan extract in rat plasma, urine, feces and bile after intragastric administration].
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Glucosides; Glycyrrhizic Acid; Hesperidin; Hydroxylation; Male; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2011 |
Aspergillus niger DLFCC-90 rhamnoside hydrolase, a new type of flavonoid glycoside hydrolase.
Topics: Amino Acid Sequence; Aspergillus niger; Cloning, Molecular; DNA, Fungal; Flavanones; Gene Expression; Glycoside Hydrolases; Hesperidin; Molecular Sequence Data; Pichia; Rutin; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2012 |
Decoupling two-dimensional NMR spectroscopy in both dimensions: pure shift NOESY and COSY.
Topics: Clarithromycin; Flavanones; Hesperidin; Magnetic Resonance Spectroscopy; Molecular Structure | 2012 |
Simultaneous UPLC analysis of three major flavonoids in granule decoctions of Fructus aurantii-type formulae.
Topics: Carbohydrate Sequence; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Citrus; Disaccharides; Drugs, Chinese Herbal; Flavanones; Flavonoids; Hesperidin; Indicators and Reagents; Limit of Detection; Molecular Sequence Data; Plant Extracts; Reference Standards; Regression Analysis; Reproducibility of Results; Solutions; Spectrophotometry, Ultraviolet | 2012 |
Effect of formula compatibility on the pharmacokinetics of components from Dachengqi Decoction [See Text] in rats.
Topics: Administration, Oral; Animals; Anthraquinones; Biphenyl Compounds; Drug Incompatibility; Emodin; Flavanones; Hesperidin; Lignans; Male; Plant Extracts; Rats; Rats, Sprague-Dawley | 2012 |
Purification of naringin and neohesperidin from Huyou (Citrus changshanensis) fruit and their effects on glucose consumption in human HepG2 cells.
Topics: Citrus; Flavanones; Fruit; Glucose; Hep G2 Cells; Hesperidin; Humans; Plant Extracts | 2012 |
Grapefruit (Citrus paradisi Macfad) phytochemicals composition is modulated by household processing techniques.
Topics: Ascorbic Acid; Beverages; Chromatography, High Pressure Liquid; Citric Acid; Citrus paradisi; Disaccharides; Flavanones; Flavonoids; Food Handling; Furocoumarins; Glycosides; Hesperidin; Limonins; Plant Extracts | 2012 |
Inhibitory effects of Citrus flavonoids on starch digestion and antihyperglycemic effects in HepG2 cells.
Topics: Amylopectin; Amylose; Animals; Citrus; Digestion; Drug Evaluation, Preclinical; Flavanones; Flavones; Flavonoids; Glucokinase; Glucose; Glycogen; Hep G2 Cells; Hesperidin; Humans; Hypoglycemic Agents; Iodine; Liver; Pancreatic alpha-Amylases; Starch | 2012 |
Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions.
Topics: Animals; Beverages; Citrus paradisi; Citrus sinensis; Dose-Response Relationship, Drug; Estrone; Flavanones; Flavonoids; Food-Drug Interactions; Fruit; Hesperidin; Humans; Kinetics; Least-Squares Analysis; Malus; Models, Biological; Nonlinear Dynamics; Oocytes; Organic Anion Transporters; Osmolar Concentration; Phlorhizin; Quercetin; Xenopus laevis | 2013 |
Targeting structural motifs of flavonoid diglycosides using collision-induced dissociation experiments on flavonoid/Pb2+ complexes.
Topics: Disaccharides; Flavanones; Flavones; Flavonoids; Glycosides; Hesperidin; Lead; Methanol; Molecular Structure; Rutin; Solutions; Spectrometry, Mass, Electrospray Ionization | 2012 |
Characterization of an α-L-Rhamnosidase from Streptomyces avermitilis.
Topics: Bacterial Proteins; Calcium; Cations, Divalent; Cloning, Molecular; Enzyme Assays; Escherichia coli; Flavanones; Glycoside Hydrolases; Gum Arabic; Hesperidin; Hydrogen-Ion Concentration; Kinetics; Recombinant Proteins; Rhamnose; Rutin; Streptomyces; Substrate Specificity; Temperature | 2013 |
Phytochemical profile and antioxidant activity of physiological drop of citrus fruits.
Topics: Antioxidants; China; Citrus; Coumaric Acids; Dietary Supplements; Disaccharides; Flavanones; Flavones; Fruit; Hesperidin; Hydroxybenzoates; Limonins; Plant Extracts; Synephrine | 2013 |
Pharmacokinetic and pharmacodynamic studies of four major phytochemical components of Da-Cheng-Qi decoction to treat acute pancreatitis.
Topics: Animals; Anthraquinones; Apoptosis; Biphenyl Compounds; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Flavanones; Hesperidin; Lignans; Male; Necrosis; Pancreas; Pancreatitis, Acute Necrotizing; Phytotherapy; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2013 |
Hydrolysis of flavanone glycosides by β-glucosidase from Pyrococcus furiosus and its application to the production of flavanone aglycones from citrus extracts.
Topics: beta-Glucosidase; Citrus; Detergents; Disaccharides; Flavanones; Flavonoids; Food Industry; Glycosides; Hesperidin; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Plant Extracts; Pyrococcus furiosus; Solvents; Substrate Specificity; Temperature | 2013 |
Selected activities of Citrus maxima Merr. fruits on human endothelial cells: enhancing cell migration and delaying cellular aging.
Topics: Antioxidants; Ascorbic Acid; Cell Movement; Cellular Senescence; Citrus; Flavanones; Fluoresceins; Fruit; Gallic Acid; Hesperidin; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide Synthase Type III; Plant Extracts; Reactive Oxygen Species; RNA, Messenger | 2014 |
[Study on HPLC fingerprint of Ganershu intermediate and determination of three active components].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chlorogenic Acid; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Flavanones; Hesperidin; Plants, Medicinal; Quality Control; Reproducibility of Results | 2013 |
Brain-targeted delivery of trans-activating transcriptor-conjugated magnetic PLGA/lipid nanoparticles.
Topics: Animals; Brain; Drug Delivery Systems; Flavanones; Glutathione; Hesperidin; Humans; Lactic Acid; Nanoparticles; Phosphatidylethanolamines; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2014 |
Antithyroid effects of naringin, hesperidin and rutin in l-T4 induced hyperthyroid rats: possible mediation through 5'DI activity.
Topics: Animals; Antioxidants; Antithyroid Agents; Electron Spin Resonance Spectroscopy; Flavanones; Free Radical Scavengers; Hesperidin; Hyperthyroidism; Iodide Peroxidase; Lipid Peroxidation; Liver; Malondialdehyde; Rats; Rutin; Thyroid Hormones; Thyroxine | 2014 |
Differentiation of Aurantii Fructus Immaturus from Poniciri Trifoliatae Fructus Immaturus using flow-injection mass spectrometric (FIMS) metabolic fingerprinting method combined with chemometrics.
Topics: Citrus; Drugs, Chinese Herbal; Flavanones; Flow Injection Analysis; Hesperidin; Mass Spectrometry; Principal Component Analysis | 2015 |
Hesperidin from Citrus seed induces human hepatocellular carcinoma HepG2 cell apoptosis via both mitochondrial and death receptor pathways.
Topics: Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; BH3 Interacting Domain Death Agonist Protein; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Citrus; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hesperidin; Humans; Inhibitory Concentration 50; Liver Neoplasms; Mitochondria; Reactive Oxygen Species; Receptors, Death Domain | 2016 |
The Influence of Naringin or Hesperidin Dietary Supplementation on Broiler Meat Quality and Oxidative Stability.
Topics: Animal Feed; Animals; Chickens; Dietary Supplements; Flavanones; Food Quality; Hesperidin; Meat; Oxidation-Reduction; Quantitative Trait, Heritable | 2015 |
Application of ionic liquids for elution of bioactive flavonoid glycosides from lime fruit by miniaturized matrix solid-phase dispersion.
Topics: Chromatography, High Pressure Liquid; Citrus aurantiifolia; Flavanones; Fruit; Hesperidin; Imidazoles; Ionic Liquids; Solid Phase Extraction; Solvents | 2016 |
Pure total flavonoids from Citrus paradisi Macfad induce leukemia cell apoptosis in vitro.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Citrus paradisi; Flavanones; Flavonoids; Hesperidin; Humans; Leukemia; Lymphocytes | 2017 |
Prioritizing pharmacokinetic drug interaction precipitants in natural products: application to OATP inhibitors in grapefruit juice.
Topics: Animals; Cells, Cultured; Citrus paradisi; Computer Simulation; Dogs; Estrone; Flavanones; Flavones; Food-Drug Interactions; Fruit and Vegetable Juices; Furocoumarins; Hesperidin; Humans; Inhibitory Concentration 50; Models, Biological; Organic Anion Transporters | 2017 |
NMR Metabolomics Investigates the Influence of Flavonoid-Enriched Rations on Chicken Plasma.
Topics: 3-Hydroxybutyric Acid; Acetic Acid; Alanine; Animal Feed; Animals; Anti-Inflammatory Agents; Antioxidants; Betaine; Chickens; Citric Acid; Creatine; Dietary Supplements; Flavanones; Glycine; Hesperidin; Lipoproteins; Metabolomics; Poultry; Succinic Acid; Vitamin E | 2017 |
Maternal Consumption of Hesperidin and Naringin Flavanones Exerts Transient Effects to Tibia Bone Structure in Female CD-1 Offspring.
Topics: Animals; Bone Development; Citrus; Female; Femur; Flavanones; Hesperidin; Lumbar Vertebrae; Mice; Plant Extracts; Tibia; X-Ray Microtomography | 2017 |
Pharmacokinetics and pharmacodynamics of Da-Cheng-Qi decoction in the liver of rats with severe acute pancreatitis.
Topics: Acute Disease; Alanine Transaminase; Animals; Anthraquinones; Aspartate Aminotransferases; Biphenyl Compounds; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Emodin; Flavanones; Hesperidin; Inflammation; Lignans; Liver; Male; Pancreatitis; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2017 |
Investigation of the interaction for three Citrus flavonoids and α-amylase by surface plasmon resonance.
Topics: alpha-Amylases; Biphenyl Compounds; Citrus; Enzymes, Immobilized; Flavanones; Flavonoids; Herb-Drug Interactions; Hesperidin; Kinetics; Picrates; Plant Extracts; Surface Plasmon Resonance | 2017 |
Comparison of the effects of dietary supplementation of flavonoids on laying hen performance, egg quality and egg nutrient profile.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Dietary Supplements; Egg Proteins; Egg Yolk; Female; Flavanones; Hesperidin; Lipids; Nutritional Status; Ovum; Quercetin; Random Allocation | 2017 |
Identification and Comparison of Constituents of Aurantii Fructus and Aurantii Fructus Immaturus by UFLC-DAD-Triple TOF-MS/MS.
Topics: Chromatography, Liquid; Citrus; Drugs, Chinese Herbal; Flavanones; Hesperidin; Mass Spectrometry; Synephrine | 2018 |
Antioxidant status, meat oxidative stability and quality characteristics of lambs fed with hesperidin, naringin or α-tocopheryl acetate supplemented diets.
Topics: alpha-Tocopherol; Animal Feed; Animals; Antioxidants; Diet; Dietary Supplements; Flavanones; Hesperidin; Malondialdehyde; Meat; Muscle, Skeletal; Sheep | 2019 |
Flavonoids, bioactive components of propolis, exhibit cytotoxic activity and induce cell cycle arrest and apoptosis in human breast cancer cells MDA-MB-231 and MCF-7 - a comparative study.
Topics: Apoptosis; Breast Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Female; Flavanones; Flavonoids; Genistein; Hesperidin; Humans; MCF-7 Cells; Propolis; Quercetin | 2018 |
UHPLC-HRMS-based tissue untargeted metabolomics study of naringin and hesperidin after dietary supplementation in chickens.
Topics: Animal Feed; Animals; Chickens; Chromatography, High Pressure Liquid; Dietary Supplements; Flavanones; Hesperidin; Meat; Metabolomics | 2018 |
Deep eutectic solvent as a green solvent for enhanced extraction of narirutin, naringin, hesperidin and neohesperidin from Aurantii Fructus.
Topics: Chromatography, High Pressure Liquid; Disaccharides; Flavanones; Green Chemistry Technology; Hesperidin; Hydrogen Bonding; Reference Standards; Solvents; Spectrophotometry, Ultraviolet | 2019 |
Antimicrobial activities of green synthesized gums-stabilized nanoparticles loaded with flavonoids.
Topics: Acanthamoeba castellanii; Amebiasis; Amebicides; Anti-Bacterial Agents; Citrus; Escherichia coli; Escherichia coli Infections; Flavanones; Green Chemistry Technology; Gum Arabic; Hesperidin; Humans; Methicillin-Resistant Staphylococcus aureus; Nanoparticles; Plant Gums; Staphylococcal Infections | 2019 |
Influence of citrus flavonoids on laying hen performance, inflammatory immune response, egg quality and yolk oxidative stability.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Chickens; Cholesterol; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Egg Yolk; Female; Flavanones; Hesperidin; Immunity, Cellular; Ovum; Oxidation-Reduction; Random Allocation; Reproduction | 2019 |
The effects of hesperidin or naringin dietary supplementation on the milk properties of dairy ewes.
Topics: alpha-Tocopherol; Animal Feed; Animals; Dietary Supplements; Fatty Acids; Female; Flavanones; Hesperidin; Milk; Sheep | 2019 |
Development and Validation of a UPLC-ESI(-)-MS/MS Methodology for the Simultaneous Quantification of Hesperidin, Naringin, and their Aglycones in Chicken Tissue Samples.
Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Chromatography, Liquid; Flavanones; Hesperidin; Reproducibility of Results; Tandem Mass Spectrometry | 2020 |
The Effects of Different Varieties of
Topics: Animals; Chromatography, High Pressure Liquid; Depression; Disaccharides; Disease Models, Animal; Drug Synergism; Drugs, Chinese Herbal; Flavanones; Hesperidin; Intestinal Absorption; Iridoids; Male; Rats; Rats, Sprague-Dawley | 2019 |
Quantitative analysis of multicomponents by single marker combined with HPLC fingerprint qualitative analyses for comprehensive evaluation of Aurantii Fructus.
Topics: Chromatography, High Pressure Liquid; Citrus; Coumarins; Disaccharides; Flavanones; Flavones; Flavonoids; Fruit; Hesperidin | 2020 |
Comparison of interaction between three similar chalconoids and α-lactalbumin: Impact on structure and functionality of α-lactalbumin.
Topics: Binding Sites; Chalcone; Chalcones; Emulsions; Flavanones; Hesperidin; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lactalbumin; Molecular Docking Simulation; Protein Binding; Protein Conformation, alpha-Helical | 2020 |
Application of "spider-web" mode in discovery and identification of Q-markers from Xuefu Zhuyu capsule.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers, Pharmacological; Capsules; Chalcone; Coumaric Acids; Drug Stability; Drugs, Chinese Herbal; Flavanones; Glucosides; Hesperidin; Hydroxybenzoates; Materia Medica; Mice; Monoterpenes; Quality Control; RAW 264.7 Cells | 2020 |
Application of accelerated solvent extraction coupled with online two-dimensional countercurrent chromatography for continuous extraction and separation of bioactive compounds from Citrus limon peel.
Topics: Animals; Cholinesterase Inhibitors; Citrus; Countercurrent Distribution; Cytochrome P-450 Enzyme System; Disaccharides; Flavanones; Flavonoids; Hesperidin; PC12 Cells; Plant Extracts; Rats; Solvents | 2020 |
Discovery and validation of quality markers of Fructus Aurantii against acetylcholinesterase using metabolomics and bioactivity assays.
Topics: Acetylcholinesterase; Animals; Biomarkers; China; Cholinesterase Inhibitors; Citrus; Coumarins; Drug Discovery; Flavanones; Hesperidin; Male; Metabolomics; Rats; Rats, Sprague-Dawley | 2021 |
NF-κB and COX-2 repression with topical application of hesperidin and naringin hydrogels augments repair and regeneration of deep dermal wounds.
Topics: Animals; Burns; Cyclooxygenase 2; Flavanones; Hesperidin; Hydrogels; Mice; NF-kappa B; Regeneration; Wound Healing | 2022 |
UHPLC/MS and NMR-Based Metabolomic Analysis of Dried Water Extract of Citrus-Type Crude Drugs.
Topics: Chromatography, High Pressure Liquid; Citrus; Flavanones; Fruit and Vegetable Juices; Glucose; Hesperidin; Magnetic Resonance Spectroscopy; Metabolomics; Methanol; Plant Extracts; Principal Component Analysis; Sucrose; Tandem Mass Spectrometry; Water | 2021 |
Naringin and Hesperidin Counteract Diclofenac-Induced Hepatotoxicity in Male Wistar Rats
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Chemical and Drug Induced Liver Injury; Cytokines; Diclofenac; Flavanones; Hesperidin; Male; Oxidative Stress; Rats; Rats, Wistar | 2021 |
Polyphenols from Citrus Tacle
Topics: Citrus; Dietary Supplements; Enzyme Inhibitors; Flavanones; Flavonoids; Fruit; Hesperidin; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Models, Molecular; Molecular Docking Simulation; Plant Extracts; Polyphenols; Protein Binding; Protein Conformation | 2021 |
A Citrus Fruit Extract High in Polyphenols Beneficially Modulates the Gut Microbiota of Healthy Human Volunteers in a Validated In Vitro Model of the Colon.
Topics: Adult; Bacteroides; Butyrates; Citrus; Clostridiales; Colon; Eubacterium; Fatty Acids, Volatile; Feces; Female; Flavanones; Fruit; Gastrointestinal Microbiome; Healthy Volunteers; Hesperidin; Humans; Male; Plant Extracts; Polyphenols | 2021 |
Involvement of phase II enzymes and efflux transporters in the metabolism and absorption of naringin, hesperidin and their aglycones in rats.
Topics: Animals; Biological Availability; Biological Transport; Flavanones; Hesperidin; Liver; Rats | 2022 |
[Determination of neohesperidin and naringin in Qingfei Paidu Granules by RP-HPLC and their transfer rates in preparation process].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Hesperidin | 2022 |