Page last updated: 2024-08-21

hesperidin and malondialdehyde

hesperidin has been researched along with malondialdehyde in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.27)18.2507
2000's4 (9.09)29.6817
2010's30 (68.18)24.3611
2020's9 (20.45)2.80

Authors

AuthorsStudies
Bonina, F; Castelli, F; Lanza, M; Marzullo, D; Saija, A; Scalese, M1
Li, QS; Lou, GY; Qian, MZ1
Li, P; Xu, L; Yang, ZL; Zhou, YQ1
Balaraman, R; Gandhi, C; Upaganalawar, A1
Abd-Ellah, MF; Aly, HA; Arafa, HM; El-Refaey, HM1
Chen, M; Deng, W; Gu, H; Lin, B; Liu, J; Sun, L; Ye, Y; Zhang, J1
Jena, GB; Kushwaha, S; Tripathi, DN; Trivedi, PP1
Guo, C; Li, F; Liao, S; Mi, H; Qi, D; Shi, X; Yang, Z; Zhang, C1
Kuncha, M; Sahu, BD; Sindhura, GJ; Sistla, R1
Akman, T; Armagan, A; Aylak, F; Bas, E; Dogan, F; Oksay, T1
El-Shazly, AM; Hamdan, DI; Mahmoud, MF; Wink, M1
Annapurna, A; Jaya Prakash, G; Krishna, KM; Madan, K; Rama Raju, GA; Ravi Krishna, CH; Sivanarayana, T; Vijaya Bharathi, B1
Liu, L; Wang, D; Wang, Y; Wu, W; Zhu, X1
Abdallah, HM; El-Khatib, AS; El-Marasy, SA; El-Shabrawy, OA; El-Shenawy, SM; Kenawy, SA1
Kar, A; Panda, S1
Khedr, NF1
Nafees, S; Rashid, S; Saidullah, B; Siddiqi, A; Sultana, S1
Arab, HH; Arafa, el-SA; El Sherbiny, GA; Elgendy, AN; Mohamed, WR; Omar, HA; Shehata, BA1
Coskun-Cevher, S; Kaltalioglu, K1
Abdel Latif, AKM; Abdel-Aziz, AM; Amin, AM; Hamdy, SM; Sayed, ON1
Cui, Z; Dong, Y; Liu, H; Ren, H; Zhu, C1
Dhingra, D; Gahalain, N; Goswami, S1
Ahmadi, K; Haidari, F; Hedayati, M; Homayouni, F; Zakerkish, M1
Grami, D; Marzouki, L; Rtibi, K; Sebai, H; Selmi, S1
Hajizadeh Moghaddam, A; Kheradmand, E; Zare, M1
Basak, N; Cetin, A; Ciftci, O; Eraslan, S; Melekoglu, R1
Charalambous, A; Charismiadou, MA; Deligeorgis, SG; Giamouri, E; Goliomytis, M; Ntetska, I; Simitzis, PE1
Caglayan, C; Kandemir, FM; Kucukler, S; Kuzu, M; Turk, E; Yildirim, S1
Erboga, Z; Güzel, S; Karaboga, I; Polat, FR; Polat, MS; Yilmaz, A1
Abudawood, M; Alaraj, ASA; Ansar, S; Hamed, SS1
Abbasi, MM; Ghorbanihaghjo, A; Kosari-Nasab, M; Salari, AA; Shokouhi, G1
Aydogmus, E; Bahadir, B; Gul, S1
Arasoglu, T; Derman, S; Duranoglu, D; Erdemir, A; Ersoz, M; Mansuroglu, B; Uzunoglu, D1
Hanchang, W; Khamchan, A; Seedadee, C; Wongmanee, N1
Abdel-Daim, MM; AlBasher, G; Aleya, L; Alfarraj, S; Almeer, R; Bahbah, EI; Bungău, SG; Elhelaly, AE; Fouda, MMA1
El-Sahar, AE; Elbaz, EM; Helmy, HS; Saad, MA; Sayed, RH; Senousy, MA1
Atabaki, R; Mehri, S; Moghimi, A; Roohbakhsh, A1
Aja, PM; Ale, BA; Aloke, C; Ani, OG; Awoke, JN; Ekpono, EU; Famurewa, AC; Igwenyi, IO; Izekwe, FI; Nwite, FE; Obasi, NA; Udeh, KU1
Akbari, G; Hassanpour, S; Khodadadeh, A1
Li, S; Luo, D; Pan, W; Qin, Q; Shang, L; Wei, Y; Xu, Y; Zhu, J1
Gelen, V; Kükürt, A; Şengül, E; Senturk, E; Tekin, S; Yıldırım, S1
Alsemeh, AE; Bendary, MA; Mandour, DA1
Abdel-Moneim, A; Ebeid, ASM; El-Shahawy, AAG; Eldin, ZE; Zanaty, MI1
Apaijit, K; Bunbupha, S; Maneesai, P; Meephat, S; Pakdeechote, P; Prasatthong, P1

Trials

1 trial(s) available for hesperidin and malondialdehyde

ArticleYear
Hesperidin Supplementation Alleviates Oxidative DNA Damage and Lipid Peroxidation in Type 2 Diabetes: A Randomized Double-Blind Placebo-Controlled Clinical Trial.
    Phytotherapy research : PTR, 2017, Volume: 31, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Blood Glucose; Deoxyguanosine; Diabetes Mellitus, Type 2; Diet; Dietary Supplements; DNA Damage; Double-Blind Method; Female; Hesperidin; Humans; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Oxidative Stress

2017

Other Studies

43 other study(ies) available for hesperidin and malondialdehyde

ArticleYear
Flavonoids as antioxidant agents: importance of their interaction with biomembranes.
    Free radical biology & medicine, 1995, Volume: 19, Issue:4

    Topics: Animals; Antioxidants; Brain; Calorimetry, Differential Scanning; Cell Membrane; Ferrous Compounds; Flavanones; Flavonoids; Hesperidin; Lipid Peroxidation; Liposomes; Male; Malondialdehyde; Oxidation-Reduction; Quercetin; Rats; Rats, Sprague-Dawley; Rutin; Thermodynamics; Thiobarbituric Acid Reactive Substances

1995
[Effect of hesperidin and rutin on oxidative modification of high density lipoprotein in vitro].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2004, Volume: 2, Issue:2

    Topics: Arteriosclerosis; Copper; Hesperidin; Lipoproteins, HDL; Malondialdehyde; Oxidation-Reduction; Rutin

2004
Modulating effect of Hesperidin on experimental murine colitis induced by dextran sulfate sodium.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2009, Volume: 16, Issue:10

    Topics: Animals; Citrus; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Hesperidin; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Organ Size; Peroxidase; Phytotherapy; Plant Extracts

2009
Protection against in vivo focal myocardial ischemia/reperfusion injury-induced arrhythmias and apoptosis by hesperidin.
    Free radical research, 2009, Volume: 43, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Arrhythmias, Cardiac; Biomarkers; Blood Pressure; Catalase; Creatine Kinase, MB Form; Disease Models, Animal; Electrocardiography; Female; Glutathione; Heart Rate; Hesperidin; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitrites; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Ventricular Pressure

2009
Hesperidin attenuates benzo[alpha] pyrene-induced testicular toxicity in rats via regulation of oxidant/antioxidant balance.
    Toxicology and industrial health, 2009, Volume: 25, Issue:6

    Topics: Animals; Antioxidants; Benzo(a)pyrene; Carcinogens; Disease Models, Animal; Glutathione; Glutathione Transferase; Hesperidin; L-Lactate Dehydrogenase; Male; Malondialdehyde; Necrosis; Organ Size; Rats; Seminiferous Tubules; Sperm Count; Spermatocytes; Superoxide Dismutase; Testicular Diseases; Testis

2009
Protective effects of hesperidin against oxidative stress of tert-butyl hydroperoxide in human hepatocytes.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:10

    Topics: Antioxidants; Blotting, Western; Cell Survival; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase-1; Hepatocytes; Hesperidin; Humans; L-Lactate Dehydrogenase; Malondialdehyde; Membrane Potentials; Mitochondrial Membranes; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Protein Transport; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; tert-Butylhydroperoxide

2010
Cardioprotective effects of hesperetin against doxorubicin-induced oxidative stress and DNA damage in rat.
    Cardiovascular toxicology, 2011, Volume: 11, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Caspase 3; Comet Assay; Cytoprotection; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Glutathione; Heart Diseases; Hesperidin; In Situ Nick-End Labeling; Male; Malondialdehyde; Myocytes, Cardiac; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Time Factors

2011
Hesperidin prevents retinal and plasma abnormalities in streptozotocin-induced diabetic rats.
    Molecules (Basel, Switzerland), 2012, Nov-01, Volume: 17, Issue:11

    Topics: Aldehyde Reductase; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Blood-Retinal Barrier; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glycation End Products, Advanced; Hesperidin; Intercellular Adhesion Molecule-1; Interleukin-1beta; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Retina; Streptozocin; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2012
Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Mar-15, Volume: 20, Issue:5

    Topics: Acute Kidney Injury; Animals; Apoptosis; Blood Urea Nitrogen; Caspase 3; Cisplatin; Creatinine; Cytoprotection; DNA Damage; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hesperidin; Inflammation; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2013
Impact of micronised purified flavonoid fraction on increased malondialdehyde and decreased metalloproteinase-2 and metalloproteinase-9 levels in varicocele: outcome of an experimentally induced varicocele.
    Andrologia, 2014, Volume: 46, Issue:4

    Topics: Animals; Diosmin; Flavonoids; Hesperidin; Male; Malondialdehyde; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Rats; Rats, Wistar; Testis; Tissue Inhibitor of Metalloproteinase-1; Varicocele

2014
Effect of hesperidin and neohesperidin from bittersweet orange (Citrus aurantium var. bigaradia) peel on indomethacin-induced peptic ulcers in rats.
    Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:3

    Topics: Animals; Citrus; Cyclooxygenase 2; Fruit; Gastric Mucosa; Glutathione; Hesperidin; Indomethacin; Male; Malondialdehyde; Peptic Ulcer; Rats, Wistar; Stomach; Tumor Necrosis Factor-alpha

2014
Protective effect of alpha glucosyl hesperidin (G-hesperidin) on chronic vanadium induced testicular toxicity and sperm nuclear DNA damage in male Sprague Dawley rats.
    Andrologia, 2015, Volume: 47, Issue:5

    Topics: Animals; Catalase; DNA Damage; Glucosides; Hesperidin; Infertility, Male; Male; Malondialdehyde; Organ Size; Rats; Rats, Sprague-Dawley; Sperm Motility; Spermatozoa; Superoxide Dismutase; Testicular Diseases; Testis; Trace Elements; Vanadium

2015
Hesperidin alleviates cognitive impairment, mitochondrial dysfunction and oxidative stress in a mouse model of Alzheimer's disease.
    Cellular and molecular neurobiology, 2014, Volume: 34, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antioxidants; Behavior, Animal; Brain; Cognition Disorders; Disease Models, Animal; Exploratory Behavior; Glutathione; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hesperidin; Hydrogen Peroxide; Malondialdehyde; Memory; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Oxidative Stress; Presenilin-1

2014
Anti-depressant effect of hesperidin in diabetic rats.
    Canadian journal of physiology and pharmacology, 2014, Volume: 92, Issue:11

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Brain-Derived Neurotrophic Factor; Depression; Diabetes Mellitus, Experimental; Fluoxetine; Glutathione; Hesperidin; Hyperglycemia; Inflammation; Interleukin-6; Male; Malondialdehyde; Oxidative Stress; Rats, Wistar; Streptozocin

2014
Antithyroid effects of naringin, hesperidin and rutin in l-T4 induced hyperthyroid rats: possible mediation through 5'DI activity.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:6

    Topics: Animals; Antioxidants; Antithyroid Agents; Electron Spin Resonance Spectroscopy; Flavanones; Free Radical Scavengers; Hesperidin; Hyperthyroidism; Iodide Peroxidase; Lipid Peroxidation; Liver; Malondialdehyde; Rats; Rutin; Thyroid Hormones; Thyroxine

2014
Protective effect of mirtazapine and hesperidin on cyclophosphamide-induced oxidative damage and infertility in rat ovaries.
    Experimental biology and medicine (Maywood, N.J.), 2015, Volume: 240, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Antioxidants; Cyclophosphamide; Female; Glutathione Peroxidase; Hesperidin; Infertility, Female; Malondialdehyde; Mianserin; Mirtazapine; Nitric Oxide; Ovary; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Superoxide Dismutase

2015
Hesperidin ameliorates trichloroethylene-induced nephrotoxicity by abrogation of oxidative stress and apoptosis in wistar rats.
    Molecular and cellular biochemistry, 2015, Volume: 406, Issue:1-2

    Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Catalase; Drug Evaluation, Preclinical; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hesperidin; Kidney; Male; Malondialdehyde; Oxidative Stress; Rats, Wistar; Renal Insufficiency; Superoxide Dismutase; Trichloroethylene

2015
Hesperidin alleviates cisplatin-induced hepatotoxicity in rats without inhibiting its antitumor activity.
    Pharmacological reports : PR, 2016, Volume: 68, Issue:2

    Topics: Alanine Transaminase; Animals; Antineoplastic Agents; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cholesterol; Cisplatin; Drug Interactions; Glutathione; Hesperidin; Liver; Male; Malondialdehyde; NF-kappa B; Nitrates; Nitrites; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Triglycerides

2016
Potential of morin and hesperidin in the prevention of cisplatin-induced nephrotoxicity.
    Renal failure, 2016, Volume: 38, Issue:8

    Topics: Animals; Antioxidants; Apoptosis; Catalase; Cisplatin; Flavonoids; Glutathione; Glutathione Peroxidase; Hesperidin; Kidney; Kidney Diseases; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Superoxide Dismutase

2016
Hesperidin and tiger nut reduced carcinogenicity of DMBA in female rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 83

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carcinogenesis; Catalase; Cyperus; Estradiol; Female; Glutathione Peroxidase; Hesperidin; Kidney; Liver; Malondialdehyde; Mammary Glands, Animal; N-Acetylneuraminic Acid; Progesterone; Protein Carbonylation; Rats, Sprague-Dawley; Superoxide Dismutase

2016
Hesperetin protects against H
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 88

    Topics: Antioxidant Response Elements; Antioxidants; Cell Death; Cell Line; Epithelial Cells; Glutathione; Heme Oxygenase-1; Hesperidin; Humans; Hydrogen Peroxide; Kelch-Like ECH-Associated Protein 1; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; RNA, Small Interfering; Signal Transduction; Superoxide Dismutase; Transfection; Up-Regulation

2017
Protective effect of hesperetin against haloperidol-induced orofacial dyskinesia and catalepsy in rats.
    Nutritional neuroscience, 2018, Volume: 21, Issue:9

    Topics: Animals; Behavior, Animal; Brain; Catalepsy; Dopamine; Dyskinesia, Drug-Induced; Dyskinesias; Glutathione; Haloperidol; Hesperidin; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Serotonin; Superoxide Dismutase

2018
Protective effects of orange (Citrus sinensis L.) peel aqueous extract and hesperidin on oxidative stress and peptic ulcer induced by alcohol in rat.
    Lipids in health and disease, 2017, Aug-14, Volume: 16, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Catalase; Citrus sinensis; Cyclooxygenase 2; Ethanol; Fruit; Gene Expression Regulation; Glutathione Peroxidase; Hesperidin; Hydrogen Peroxide; Male; Malondialdehyde; Omeprazole; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Stomach Ulcer; Sulfhydryl Compounds; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2017
Neuroprotective effect of hesperetin and nano-hesperetin on recognition memory impairment and the elevated oxygen stress in rat model of Alzheimer's disease.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Alzheimer Disease; Animals; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hesperidin; Hippocampus; Male; Malondialdehyde; Memory Disorders; Nanoparticles; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase

2018
The beneficial effects of nerolidol and hesperidin on surgically induced endometriosis in a rat model
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2018, Volume: 34, Issue:11

    Topics: Animals; Disease Models, Animal; Endometriosis; Female; Glutathione; Hesperidin; Malondialdehyde; Rats; Rats, Wistar; Sesquiterpenes; Superoxide Dismutase; Treatment Outcome; Uterus

2018
Antioxidant status, meat oxidative stability and quality characteristics of lambs fed with hesperidin, naringin or α-tocopheryl acetate supplemented diets.
    Journal of the science of food and agriculture, 2019, Jan-15, Volume: 99, Issue:1

    Topics: alpha-Tocopherol; Animal Feed; Animals; Antioxidants; Diet; Dietary Supplements; Flavanones; Hesperidin; Malondialdehyde; Meat; Muscle, Skeletal; Sheep

2019
Protective Effect of Hesperidin on Sodium Arsenite-Induced Nephrotoxicity and Hepatotoxicity in Rats.
    Biological trace element research, 2019, Volume: 189, Issue:1

    Topics: Animals; Arsenites; Glutathione; Glutathione Peroxidase; Hesperidin; Kidney; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Research Design; Sodium Compounds; Superoxide Dismutase

2019
Effect of hesperetin on inflammatory and oxidative status in trinitrobenzene sulfonic acid-induced experimental colitis model.
    Cellular and molecular biology (Noisy-le-Grand, France), 2018, Aug-30, Volume: 64, Issue:11

    Topics: Animals; Antioxidants; Colitis; Enzyme-Linked Immunosorbent Assay; Hesperidin; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-6; Lipid Peroxidation; Male; Malondialdehyde; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Superoxide Dismutase; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha

2018
Hesperidin alleviates zinc oxide nanoparticle induced hepatotoxicity and oxidative stress.
    BMC pharmacology & toxicology, 2018, Oct-19, Volume: 19, Issue:1

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutathione; Hesperidin; Liver; Male; Malondialdehyde; Nanoparticles; Oxidative Stress; Rats, Wistar; Superoxide Dismutase; Zinc Oxide

2018
Hesperidin attenuates depression-related symptoms in mice with mild traumatic brain injury.
    Life sciences, 2018, Nov-15, Volume: 213

    Topics: Animals; Antidepressive Agents; Brain Concussion; Cytokines; Depression; Depressive Disorder; Disease Models, Animal; Flavonoids; Hesperidin; Hippocampus; Inflammation; Interleukin-1beta; Male; Malondialdehyde; Mice; Nerve Growth Factors; Neuroprotective Agents; Oxidative Stress; Tumor Necrosis Factor-alpha

2018
Neuroprotective Effects of Hesperidin on Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage in Rats: Biochemical, Pathologic, and Histomorphometric Analysis.
    World neurosurgery, 2019, Volume: 122

    Topics: Animals; Antioxidants; Basilar Artery; Disease Models, Animal; Drug Administration Schedule; Hesperidin; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Random Allocation; Rats, Wistar; Subarachnoid Hemorrhage; Vasospasm, Intracranial

2019
Comparative evaluation of hesperetin loaded nanoparticles for anticancer activity against C6 glioma cancer cells.
    Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1

    Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Carriers; Glioma; Glutathione; Hesperidin; Humans; Malondialdehyde; Nanoparticles; Oxidative Stress; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Superoxide Dismutase

2019
Hesperidin ameliorates pancreatic β-cell dysfunction and apoptosis in streptozotocin-induced diabetic rat model.
    Life sciences, 2019, Oct-15, Volume: 235

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Blood Glucose; Diabetes Mellitus, Experimental; Eating; Endoplasmic Reticulum Stress; Glutathione Peroxidase; Heat-Shock Proteins; Hesperidin; Homeodomain Proteins; Inflammation; Insulin; Insulin-Secreting Cells; Male; Malondialdehyde; Oxidative Stress; Pancreas; Protective Agents; Rats; Superoxide Dismutase; Trans-Activators; Transcription Factor CHOP; Tumor Necrosis Factor-alpha; Tyrosine

2019
Protective effects of hesperidin and diosmin against acrylamide-induced liver, kidney, and brain oxidative damage in rats.
    Environmental science and pollution research international, 2019, Volume: 26, Issue:34

    Topics: Acrylamide; Animals; Antioxidants; Biomarkers; Brain; Catalase; Creatinine; Diosmin; DNA Damage; Glutathione; Glutathione Peroxidase; Hazardous Substances; Hesperidin; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase

2019
Aberrations of miR-126-3p, miR-181a and sirtuin1 network mediate Di-(2-ethylhexyl) phthalate-induced testicular damage in rats: The protective role of hesperidin.
    Toxicology, 2020, 03-30, Volume: 433-434

    Topics: Animals; Antioxidants; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Hesperidin; Male; Malondialdehyde; MicroRNAs; Oxidative Stress; Plasticizers; Rats; Rats, Wistar; Sirtuin 1; Testis; Time Factors

2020
Protective effects of maternal administration of curcumin and hesperidin in the rat offspring following repeated febrile seizure: Role of inflammation and TLR4.
    International immunopharmacology, 2020, Volume: 86

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Antioxidants; Curcumin; Cytokines; Electrophysiological Phenomena; Female; Glutathione; Hesperidin; Hippocampus; Hyperthermia; Inflammation; Male; Malondialdehyde; Maze Learning; Memory, Short-Term; Mothers; Oxidative Stress; Rats, Wistar; Seizures, Febrile; Toll-Like Receptor 4

2020
Hesperidin protects against cadmium-induced pancreatitis by modulating insulin secretion, redox imbalance and iNOS/NF-ĸB signaling in rats.
    Life sciences, 2020, Oct-15, Volume: 259

    Topics: Animals; Antioxidants; Cadmium; Catalase; Glutathione; Hesperidin; Inflammation; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Malondialdehyde; NF-kappa B; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Pancreatitis; Protective Agents; Rats; Rats, Wistar; Signal Transduction; Superoxide Dismutase

2020
Prenatal exposure to hesperidin improves reflexive motor behaviors in mice offspring.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2020, Volume: 80, Issue:7

    Topics: Animals; Female; Glutathione Peroxidase; Hand Strength; Hesperidin; Male; Malondialdehyde; Mice; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Reflex; Superoxide Dismutase

2020
Hesperidin ameliorates liver ischemia/reperfusion injury via activation of the Akt pathway.
    Molecular medicine reports, 2020, Volume: 22, Issue:6

    Topics: Alanine Transaminase; Animals; Antioxidants; Apoptosis; China; Hepatocytes; Hesperidin; Ischemia; Liver; Liver Diseases; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reperfusion Injury; Signal Transduction; Tumor Necrosis Factor-alpha

2020
The protective effects of hesperidin and curcumin on 5-fluorouracil-induced nephrotoxicity in mice.
    Environmental science and pollution research international, 2021, Volume: 28, Issue:34

    Topics: Animals; Antioxidants; Curcumin; Fluorouracil; Glutathione; Hesperidin; Humans; Kidney; Malondialdehyde; Mice; Oxidative Stress; Renal Insufficiency; Superoxide Dismutase

2021
Histological and imunohistochemical alterations of hippocampus and prefrontal cortex in a rat model of Alzheimer like-disease with a preferential role of the flavonoid "hesperidin".
    Journal of molecular histology, 2021, Volume: 52, Issue:5

    Topics: Alzheimer Disease; Animals; Behavior, Animal; Body Weight; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glutathione; Hesperidin; Hippocampus; Immunohistochemistry; Male; Malondialdehyde; Organ Size; Phosphorylation; Prefrontal Cortex; Pyramidal Cells; Rats, Sprague-Dawley; Synaptophysin; tau Proteins

2021
A novel layered double hydroxide-hesperidin nanoparticles exert antidiabetic, antioxidant and anti-inflammatory effects in rats with diabetes.
    Molecular biology reports, 2021, Volume: 48, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Hesperidin; Hydroxides; Hypoglycemic Agents; Insulin; Male; Malondialdehyde; Nanoparticles; Oxidative Stress; PPAR gamma; Rats

2021
Hesperidin alleviates vascular dysfunction and remodelling in high-fat/high-fructose diet-fed rats by modulating oxidative stress, inflammation, AdipoR1, and eNOS expression.
    Tissue & cell, 2022, Volume: 78

    Topics: Adiponectin; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Diet, High-Fat; Drinking Water; Fructose; Hesperidin; Inflammation; Interleukin-6; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Superoxides; Tumor Necrosis Factor-alpha

2022