hesperetin and apigenin

hesperetin has been researched along with apigenin in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (9.68)18.2507
2000's7 (22.58)29.6817
2010's19 (61.29)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Barbhuiya, TK; Jayaprakash, V; Mohd Siddique, MU; Sinha, BN1
Augereau, JM; Billon, M; Gleye, J; Herbert, JM; Lale, A; Leconte, M1
Habtemariam, S1
Ash, K; Grohmann, K; Manthey, CL; Manthey, JA; Montanari, A1
Morris, ME; Yang, X; Zhang, S1
Asada, S; Imai, Y; Sugimoto, Y; Tsukahara, S1
Domina, NG; Khlebnikov, AI; Kirpotina, LN; Quinn, MT; Schepetkin, IA1
Katavic, PL; Lamb, K; Navarro, H; Prisinzano, TE1
Kirchmair, J; Laggner, C; Langer, T; Nashev, LG; Odermatt, A; Schuster, D; Wolber, G1
Gavande, N; Hanrahan, JR; Hibbs, DE; Kim, MS; Matin, A; Roubin, RH; Salam, NK; Yang, NX1
Amić, D; Lucić, B1
Ataide Martins, JP; Borges de Melo, E; Castro Ferreira, MM; Friozi, MC; Marinho Jorge, TC1
Itoh, T; Sakakibara, H; Shimoi, K; Takemura, H; Yamamoto, K1
Goettert, M; Koch, P; Laufer, S; Merfort, I; Schattel, V1
Cai, S; Chu, L; Gao, F; Ji, B; Jia, G; Liu, J; Liu, Y; Wang, A; Wei, Y; Wu, W; Xie, L; Zhang, D; Zhou, F1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Doddareddy, MR; Gavande, N; Groundwater, PW; Hibbs, DE; Matin, A; Nammi, S; Roubin, RH1
Atrahimovich, D; Khatib, S; Vaya, J1
Bicknell, KA; Farrimond, JA; Putnam, SE; Swioklo, S; Watson, KA; Williamson, EM1
Cahlikova, L; Chlebek, J; Havrankova, J; Hofman, J; Hostalkova, A; Lundova, T; Musilek, K; Novotna, E; Wsol, V; Zemanova, L1
Akram, M; Atanasov, AG; Ateba, SB; Bachmann, F; Davis, RA; Engeli, RT; Krenn, L; Leugger, S; Njamen, D; Odermatt, A; Schuster, D; Stuppner, H; Temml, V; Vuorinen, A; Waltenberger, B1
Guo, CL; Guo, SJ; Jiang, B; Li, N; Li, XQ; Shi, DY; Wang, LJ1
Cho, YB; Han, JS; Hwang, BY; Kim, JG; Kwon, H; Le, TPL; Lee, D; Lee, JW; Lee, MK1
Liu, F; Peng, Y; Ye, J; Yuan, J1
Fang, F; Huang, Z; Wang, J; Wong, CW1
Leung, LK; Li, F; Lin, SM; Ye, L1
Bi, S; Pang, B; Wang, T; Wang, Y; Yan, L1
Abd-Alla, MH; Bagy, MK; Bashandy, SR; El-enany, AW1
Fan, G; Song, F; Wu, F; Ye, X1
Keck, CM; Müller, RH; Romero, GB1
El Daibani, AA; Liu, MC; Luo, L; Mei, X; Xi, Y; Yasuda, S; Zhou, C1

Reviews

2 review(s) available for hesperetin and apigenin

ArticleYear
Phytoestrogens and their synthetic analogues as substrate mimic inhibitors of CYP1B1.
    European journal of medicinal chemistry, 2019, Feb-01, Volume: 163

    Topics: Animals; Antineoplastic Agents, Phytogenic; Classification; Cluster Analysis; Cytochrome P-450 CYP1B1; Enzyme Inhibitors; Humans; Molecular Mimicry; Neoplasms; Phytoestrogens

2019
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.
    European journal of medicinal chemistry, 2018, May-10, Volume: 151

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypoglycemic Agents; Molecular Docking Simulation; Structure-Activity Relationship

2018

Other Studies

29 other study(ies) available for hesperetin and apigenin

ArticleYear
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.
    Journal of natural products, 1996, Volume: 59, Issue:3

    Topics: Amino Acid Sequence; Blood Coagulation; Cell Adhesion; Endotoxins; Flavonoids; Humans; In Vitro Techniques; Interleukin-1; Molecular Sequence Data; Monocytes

1996
Flavonoids as inhibitors or enhancers of the cytotoxicity of tumor necrosis factor-alpha in L-929 tumor cells.
    Journal of natural products, 1997, Volume: 60, Issue:8

    Topics: Animals; Apoptosis; Drug Synergism; Flavonoids; Mice; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1997
Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human monocytes.
    Journal of natural products, 1999, Volume: 62, Issue:3

    Topics: Citrus; Cyclic AMP; Flavonoids; Humans; In Vitro Techniques; Lipopolysaccharides; Monocytes; Phosphodiesterase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha

1999
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.
    Molecular pharmacology, 2004, Volume: 65, Issue:5

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Division; Chemokines, CC; Dose-Response Relationship, Drug; Drug Interactions; Flavonoids; Humans; Mitoxantrone; Neoplasm Proteins; Tumor Cells, Cultured

2004
Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance.
    Cancer research, 2004, Jun-15, Volume: 64, Issue:12

    Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavonoids; Genistein; Humans; K562 Cells; Neoplasm Proteins; Topotecan; Transduction, Genetic; Tritium

2004
Improved quantitative structure-activity relationship models to predict antioxidant activity of flavonoids in chemical, enzymatic, and cellular systems.
    Bioorganic & medicinal chemistry, 2007, Feb-15, Volume: 15, Issue:4

    Topics: Animals; Antioxidants; Drug Design; Flavonoids; Humans; Phagocytes; Phenols; Polyphenols; Quantitative Structure-Activity Relationship

2007
Flavonoids as opioid receptor ligands: identification and preliminary structure-activity relationships.
    Journal of natural products, 2007, Volume: 70, Issue:8

    Topics: Flavonoids; Humans; Hypericum; Ligands; Narcotic Antagonists; Plants, Medicinal; Receptors, Opioid; Receptors, Opioid, kappa; Structure-Activity Relationship

2007
Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: 17-Hydroxysteroid Dehydrogenases; Catalysis; Cell Line; Drug Evaluation, Preclinical; Enzyme Inhibitors; Flavonoids; Humans; Models, Chemical; Small Molecule Libraries

2008
7-Hydroxy-benzopyran-4-one derivatives: a novel pharmacophore of peroxisome proliferator-activated receptor alpha and -gamma (PPARalpha and gamma) dual agonists.
    Journal of medicinal chemistry, 2009, Nov-12, Volume: 52, Issue:21

    Topics: Benzopyrans; Cell Line; Humans; PPAR alpha; PPAR gamma; Structure-Activity Relationship

2009
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
Multivariate QSAR study on the antimutagenic activity of flavonoids against 3-NFA on Salmonella typhimurium TA98.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:10

    Topics: Algorithms; Antimutagenic Agents; Flavonoids; Fluorenes; Least-Squares Analysis; Models, Biological; Models, Molecular; Mutagens; Quantitative Structure-Activity Relationship; Salmonella typhimurium

2010
Selective inhibition of methoxyflavonoids on human CYP1B1 activity.
    Bioorganic & medicinal chemistry, 2010, Sep-01, Volume: 18, Issue:17

    Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Flavonoids; Humans; Models, Molecular; Structure-Activity Relationship

2010
Biological evaluation and structural determinants of p38α mitogen-activated-protein kinase and c-Jun-N-terminal kinase 3 inhibition by flavonoids.
    Chembiochem : a European journal of chemical biology, 2010, Dec-10, Volume: 11, Issue:18

    Topics: Animals; Flavonoids; Humans; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinase 14; Models, Molecular; Protein Kinase Inhibitors; Structure-Activity Relationship

2010
Comparative study on antioxidant capacity of flavonoids and their inhibitory effects on oleic acid-induced hepatic steatosis in vitro.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Antioxidants; Cell Line; Fatty Liver; Flavonoids; Humans; In Vitro Techniques; Oleic Acid; Reactive Oxygen Species; Triglycerides

2011
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
The discovery of novel isoflavone pan peroxisome proliferator-activated receptor agonists.
    Bioorganic & medicinal chemistry, 2013, Feb-01, Volume: 21, Issue:3

    Topics: Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Isoflavones; Models, Molecular; Molecular Structure; Peroxisome Proliferator-Activated Receptors; Structure-Activity Relationship

2013
The effects and mechanism of flavonoid-rePON1 interactions. Structure-activity relationship study.
    Bioorganic & medicinal chemistry, 2013, Jun-01, Volume: 21, Issue:11

    Topics: Allosteric Site; Aryldialkylphosphatase; Copper; Flavonoids; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Molecular Docking Simulation; Oxidation-Reduction; Protein Binding; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan

2013
Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
    Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11

    Topics: Cell Differentiation; Flavonoids; Humans; Mesenchymal Stem Cells; Molecular Structure; Osteogenesis; Signal Transduction; Structure-Activity Relationship

2015
Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment.
    Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Apigenin; Daunorubicin; Enzyme Inhibitors; Flavones; Flavonoids; HCT116 Cells; Humans; Luteolin; Molecular Conformation; Molecular Structure; Neoplasms

2015
Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.
    Journal of natural products, 2017, 04-28, Volume: 80, Issue:4

    Topics: 17-Hydroxysteroid Dehydrogenases; Biological Products; Enzyme Inhibitors; Etiocholanolone; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Testosterone

2017
Sesquiterpenoids from
    Journal of natural products, 2021, 03-26, Volume: 84, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Chrysanthemum; Flavones; Flowers; Glucosides; Lactones; Mice; Molecular Structure; Nitric Oxide; Phytochemicals; Plants, Medicinal; RAW 264.7 Cells; Republic of Korea; Sesquiterpenes

2021
Determination of active components in rosemary by capillary electrophoresis with electrochemical detection.
    Journal of pharmaceutical and biomedical analysis, 2005, Sep-15, Volume: 39, Issue:3-4

    Topics: Antioxidants; Apigenin; Buffers; Caffeic Acids; Chromatography, High Pressure Liquid; Cinnamates; Coumaric Acids; Depsides; Electrochemistry; Electrodes; Electrophoresis, Capillary; Flavonoids; Hesperidin; Hydrogen-Ion Concentration; Ions; Luteolin; Models, Chemical; Plant Extracts; Regression Analysis; Rosmarinic Acid; Rosmarinus; Temperature; Time Factors

2005
Structural activity relationship of flavonoids with estrogen-related receptor gamma.
    FEBS letters, 2010, Jan-04, Volume: 584, Issue:1

    Topics: Apigenin; Flavanones; Flavonoids; Genistein; Heat-Shock Proteins; HeLa Cells; Hesperidin; Humans; Isoflavones; Luteolin; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Receptors, Estrogen; Structure-Activity Relationship; Transcription Factors; Transcriptional Activation

2010
Dietary flavones and flavonones display differential effects on aromatase (CYP19) transcription in the breast cancer cells MCF-7.
    Molecular and cellular endocrinology, 2011, Sep-15, Volume: 344, Issue:1-2

    Topics: Apigenin; Aromatase; Aromatase Inhibitors; Breast Neoplasms; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Enzyme Assays; Female; Flavanones; Genes, Reporter; Hesperidin; Humans; Luciferases, Firefly; Luteolin; Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Transcription Factor AP-1; Transcription, Genetic

2011
An investigation on the interaction of DNA with hesperetin/apigenin in the presence of CTAB by resonance Rayleigh light scattering technique and its analytical application.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 90

    Topics: Apigenin; Cetrimonium; Cetrimonium Compounds; Detergents; DNA; Hesperidin; Hydrogen-Ion Concentration; Light; Limit of Detection; Spectrometry, Fluorescence; Vibration

2012
Rhizobium tibeticum activated with a mixture of flavonoids alleviates nickel toxicity in symbiosis with fenugreek (Trigonella foenum graecum L.).
    Ecotoxicology (London, England), 2014, Volume: 23, Issue:5

    Topics: Apigenin; Flavonoids; Glutamate-Ammonia Ligase; Hesperidin; Nickel; Nitrogen Fixation; Nod Signaling Adaptor Proteins; Phenylalanine Ammonia-Lyase; Plant Exudates; Plant Root Nodulation; Random Allocation; Rhizobium; Stress, Physiological; Symbiosis; Trigonella

2014
[Simultaneous determination of 11 constituents in Citrus reticulate 'Chachi' by high performance liquid chromatography].
    Se pu = Chinese journal of chromatography, 2015, Volume: 33, Issue:4

    Topics: Apigenin; Chromatography, High Pressure Liquid; Citrus; Flavones; Flavonoids; Furaldehyde; Glucosides; Hesperidin

2015
Simple low-cost miniaturization approach for pharmaceutical nanocrystals production.
    International journal of pharmaceutics, 2016, Mar-30, Volume: 501, Issue:1-2

    Topics: Apigenin; Ascorbic Acid; Chemistry, Pharmaceutical; Cyclosporine; Hesperidin; Miniaturization; Nanoparticles; Particle Size; Resveratrol; Stilbenes; Suspensions; Technology, Pharmaceutical

2016
Sulfation of hesperetin, naringenin and apigenin by the human cytosolic sulfotransferases: a comprehensive analysis.
    Natural product research, 2020, Volume: 34, Issue:6

    Topics: Apigenin; Cell Line, Tumor; Cytosol; Flavanones; Hesperidin; Humans; Intestinal Mucosa; Kidney; Liver; Lung; Metabolic Networks and Pathways; Sulfates; Sulfotransferases

2020