hercynine and cysteine-sulfinic-acid

hercynine has been researched along with cysteine-sulfinic-acid* in 1 studies

Other Studies

1 other study(ies) available for hercynine and cysteine-sulfinic-acid

ArticleYear
Cysteine oxidation reactions catalyzed by a mononuclear non-heme iron enzyme (OvoA) in ovothiol biosynthesis.
    Organic letters, 2014, Apr-18, Volume: 16, Issue:8

    OvoA in ovothiol biosynthesis is a mononuclear non-heme iron enzyme catalyzing the oxidative coupling between histidine and cysteine. It can also catalyze the oxidative coupling between hercynine and cysteine, yet with a different regio-selectivity. Due to the potential application of this reaction for industrial ergothioneine production, in this study, we systematically characterized OvoA by a combination of three different assays. Our studies revealed that OvoA can also catalyze the oxidation of cysteine to either cysteine sulfinic acid or cystine. Remarkably, these OvoA-catalyzed reactions can be systematically modulated by a slight modification of one of its substrates, histidine.

    Topics: Betaine; Catalysis; Cysteine; Cysteine Dioxygenase; Heme; Histidine; Humans; Methylhistidines; Models, Biological; Molecular Structure; Mycobacterium smegmatis; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction

2014