heptakis(2,6-o-dimethyl)beta-cyclodextrin and tadalafil

heptakis(2,6-o-dimethyl)beta-cyclodextrin has been researched along with tadalafil in 1 studies

Compound Research Comparison

Studies (heptakis(2,6-o-dimethyl)beta-cyclodextrin)	Trials (heptakis(2,6-o-dimethyl)beta-cyclodextrin)	Recent Studies (post-2010) (heptakis(2,6-o-dimethyl)beta-cyclodextrin)	Studies (tadalafil)	Trials (tadalafil)	Recent Studies (post-2010) (tadalafil)
148	0	45	1,742	392	1,089

Protein Interaction Comparison

Protein	Taxonomy	tadalafil (IC50)
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)	0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)	0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)	0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)	0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	0.0012
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	0.0012
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase	Homo sapiens (human)	0.0012
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase	Homo sapiens (human)	0.0012
cGMP-dependent 3',5'-cyclic phosphodiesterase	Homo sapiens (human)	3.0704
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	Homo sapiens (human)	2.928
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	Homo sapiens (human)	3.0704
cGMP-specific 3',5'-cyclic phosphodiesterase	Homo sapiens (human)	0.5153
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	Bos taurus (cattle)	5.1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	Bos taurus (cattle)	4.05
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	Homo sapiens (human)	2.928
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	Bos taurus (cattle)	5.1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	Homo sapiens (human)	2.928
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	Bos taurus (cattle)	5.1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	Bos taurus (cattle)	5.1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)	9.2
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	Homo sapiens (human)	2.928
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	Homo sapiens (human)	2.507
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	Homo sapiens (human)	3.0704
Synaptic vesicular amine transporter	Rattus norvegicus (Norway rat)	0.012
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	4.6028
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)	9.2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)	4.6028
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	Homo sapiens (human)	3.0704
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	Homo sapiens (human)	2.928
cGMP-specific 3',5'-cyclic phosphodiesterase	Bos taurus (cattle)	0.0075
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	Bos taurus (cattle)	5.1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	Homo sapiens (human)	0.8575
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	Homo sapiens (human)	3.0704
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	Homo sapiens (human)	3.0704

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Badr-Eldin, SM; Elkheshen, SA; Ghorab, MM	1

Other Studies

1 other study(ies) available for heptakis(2,6-o-dimethyl)beta-cyclodextrin and tadalafil

Article	Year
Inclusion complexes of tadalafil with natural and chemically modified beta-cyclodextrins. I: preparation and in-vitro evaluation. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 70, Issue:3 Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Oral; beta-Cyclodextrins; Calorimetry, Differential Scanning; Carbolines; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Compounding; Excipients; Freeze Drying; Kinetics; Phosphodiesterase Inhibitors; Solubility; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tablets; Tadalafil; Technology, Pharmaceutical	2008

Article

Year

Inclusion complexes of tadalafil with natural and chemically modified beta-cyclodextrins. I: preparation and in-vitro evaluation.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 70, Issue:3

Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Oral; beta-Cyclodextrins; Calorimetry, Differential Scanning; Carbolines; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Compounding; Excipients; Freeze Drying; Kinetics; Phosphodiesterase Inhibitors; Solubility; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tablets; Tadalafil; Technology, Pharmaceutical

2008