heptakis(2,6-o-dimethyl)beta-cyclodextrin has been researched along with tacrolimus in 1 studies
| Studies (heptakis(2,6-o-dimethyl)beta-cyclodextrin) | Trials (heptakis(2,6-o-dimethyl)beta-cyclodextrin) | Recent Studies (post-2010) (heptakis(2,6-o-dimethyl)beta-cyclodextrin) | Studies (tacrolimus) | Trials (tacrolimus) | Recent Studies (post-2010) (tacrolimus) |
|---|---|---|---|---|---|
| 148 | 0 | 45 | 17,757 | 2,319 | 6,661 |
| Protein | Taxonomy | heptakis(2,6-o-dimethyl)beta-cyclodextrin (IC50) | tacrolimus (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 7.18 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.58 | |
| Cytochrome P450 3A5 | Homo sapiens (human) | 0.385 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.0021 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | 0.2547 | |
| Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Homo sapiens (human) | 0.0148 | |
| Splicing factor 3B subunit 3 | Homo sapiens (human) | 0.0123 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 3.3 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 3.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arima, H; Hirayama, F; Uekama, K; Yunomae, K | 1 |
1 other study(ies) available for heptakis(2,6-o-dimethyl)beta-cyclodextrin and tacrolimus
| Article | Year |
|---|---|
Contribution of P-glycoprotein to the enhancing effects of dimethyl-beta-cyclodextrin on oral bioavailability of tacrolimus.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; beta-Cyclodextrins; Biological Availability; Blotting, Western; Caco-2 Cells; Cyclodextrins; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Immunosuppressive Agents; Intestinal Absorption; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Silver Staining; Solubility; Tacrolimus; Vinblastine | 2001 |