Compounds > heptakis(2,6-o-dimethyl)beta-cyclodextrin
Page last updated: 2024-09-03

heptakis(2,6-o-dimethyl)beta-cyclodextrin and nifedipine

heptakis(2,6-o-dimethyl)beta-cyclodextrin has been researched along with nifedipine in 2 studies

Compound Research Comparison

Studies
(heptakis(2,6-o-dimethyl)beta-cyclodextrin)		Trials
(heptakis(2,6-o-dimethyl)beta-cyclodextrin)		Recent Studies (post-2010)
(heptakis(2,6-o-dimethyl)beta-cyclodextrin)		Studies
(nifedipine)		Trials
(nifedipine)		Recent Studies (post-2010) (nifedipine)
14804516,0242,4961,505

Protein Interaction Comparison

ProteinTaxonomyheptakis(2,6-o-dimethyl)beta-cyclodextrin (IC50)nifedipine (IC50)
perilipin-5Homo sapiens (human)7.133
perilipin-1Homo sapiens (human)9.619
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)8.376
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.0429
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.035
Cytochrome P450 1A2Homo sapiens (human)0.3
Cytochrome P450 3A4Homo sapiens (human)10
Adenosine receptor A3Homo sapiens (human)7.214
Cytochrome P450 2C9 Homo sapiens (human)3.06
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)10
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)7.214
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.0385
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)6.1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)1.12
Adenosine receptor A1Homo sapiens (human)7.701
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)1.12
C-C chemokine receptor type 2Homo sapiens (human)2.191
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)7.214
Cytochrome P450 2J2Homo sapiens (human)3.06
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.4733
Voltage-dependent L-type calcium channel subunit alpha-1CMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.035
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0394
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.02
Potassium channel subfamily K member 2 Bos taurus (cattle)8.2
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)1.5
Voltage-dependent L-type calcium channel subunit alpha-1DMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1FMus musculus (house mouse)1.2

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abanumay, KA; Al-Angary, AA; Bayomi, MA1
Beig, A; Dahan, A; Miller, JM1

Other Studies

2 other study(ies) available for heptakis(2,6-o-dimethyl)beta-cyclodextrin and nifedipine

ArticleYear
Effect of inclusion complexation with cyclodextrins on photostability of nifedipine in solid state.
    International journal of pharmaceutics, 2002, Aug-28, Volume: 243, Issue:1-2

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrins; Calorimetry, Differential Scanning; Cyclodextrins; Drug Stability; Fluorescence; Light; Nifedipine; Photochemistry; Solubility; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction

2002
The interaction of nifedipine with selected cyclodextrins and the subsequent solubility-permeability trade-off.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2013, Volume: 85, Issue:3 Pt B

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Absorption; Alkanes; beta-Cyclodextrins; Biological Transport; Calcium Channel Blockers; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cyclodextrins; Drug Delivery Systems; Drug Interactions; Humans; Intestinal Absorption; Intestines; Nifedipine; Permeability; Solubility

2013